TY - JOUR A1 - Sree, K. Sowjanya A1 - Keresztes, Aron A1 - Müller-Röber, Bernd A1 - Brandt, Ronny A1 - Eberius, Matthias A1 - Fischer, Wolfgang A1 - Appenroth, Klaus-J. T1 - Phytotoxicity of cobalt ions on the duckweed Lemna minor - Morphology, ion uptake, and starch accumulation JF - Chemosphere : chemistry, biology and toxicology as related to environmental problems N2 - Cobalt (Co2+) inhibits vegetative growth of Lemna minor gradually from 1 mu M to 100 mu M. Fronds accumulated up to 21 mg Co2+ g(-1) dry weight at 10 mu M external Co2+ indicating hyperaccumulation. Interestingly, accumulation of Co2+ did not decrease the iron (Fe) content in fronds, highlighting L. minor as a suitable system for studying effects of Co2+ undisturbed by Fe deficiency symptoms unlike most other plants. Digital image analysis revealed the size distribution of fronds after Co2+ treatment and also a reduction in pigmentation of newly formed daughter fronds unlike the mother fronds during the 7-day treatment. Neither chlorophyll nor photosystem II fluorescence changed significantly during the initial 4 d, indicating effective photosynthesis. During the later phase of the 7-day treatment, however, chlorophyll content and photosynthetic efficiency decreased in the Co2+-treated daughter fronds, indicating that Co2+ inhibits the biosynthesis of chlorophyll rather than leading to the destruction of pre-existing pigment molecules. In addition, during the first 4 d of Co2+ treatment starch accumulated in the fronds and led to the transition of chloroplasts to chloro-amyloplasts and amylo-chloroplasts, while starch levels strongly decreased thereafter. (C) 2015 Elsevier Ltd. All rights reserved. KW - Chloroplast KW - Cobalt KW - Lemnaceae KW - Lemna minor KW - Phytotoxicity KW - Starch accumulation Y1 - 2015 U6 - https://doi.org/10.1016/j.chemosphere.2015.03.008 SN - 0045-6535 SN - 1879-1298 VL - 131 SP - 149 EP - 156 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Flöel, Agnes A1 - Werner, Cordula A1 - Grittner, Ulrike A1 - Hesse, Stefan A1 - Jöbges, Michael A1 - Knauss, Janet A1 - Seifert, Michael A1 - Steinhagen-Thiessen, Elisabeth A1 - Goevercin, Mehmet A1 - Dohle, Christian A1 - Fischer, Wolfgang A1 - Schlieder, Regina A1 - Nave, Alexander Heinrich A1 - Meisel, Andreas A1 - Ebinger, Martin A1 - Wellwood, Ian T1 - Physical fitness training in Subacute Stroke (PHYS-STROKE) - study protocol for a randomised controlled trial JF - Trials N2 - Background: Given the rising number of strokes worldwide, and the large number of individuals left with disabilities after stroke, novel strategies to reduce disability, increase functions in the motor and the cognitive domains, and improve quality of life are of major importance. Physical activity is a promising intervention to address these challenges but, as yet, there is no study demonstrating definite outcomes. Our objective is to assess whether additional treatment in the form of physical fitness-based training for patients early after stroke will provide benefits in terms of functional outcomes, in particular gait speed and the Barthel Index (co-primary outcome measures) reflecting activities of daily living (ADL). We will gather secondary functional outcomes as well as mechanistic parameters in an exploratory approach. Methods/Design: Our phase III randomised controlled trial will recruit 215 adults with moderate to severe limitations of walking and ADL 5 to 45 days after stroke onset. Participants will be stratified for the prognostic variables of "centre", "age", and "stroke severity", and randomly assigned to one of two groups. The interventional group receives physical fitness training delivered as supported or unsupported treadmill training (cardiovascular active aerobic training; five times per week, over 4 weeks; each session 50 minutes; total of 20 additional physical fitness training sessions) in addition to standard rehabilitation treatment. The control intervention consists of relaxation sessions (non-cardiovascular active; five times per week week, over 4 weeks; each session 50 minutes) in addition to standard rehabilitation treatment. Co-primary efficacy endpoints will be gait speed (in m/s, 10 m walk) and the Barthel Index (100 points total) at 3 months post-stroke, compared to baseline measurements. Secondary outcomes include standard measures of quality of life, sleep and mood, cognition, arm function, maximal oxygen uptake, and cardiovascular risk factors including blood pressure, pulse, waist-to-hip ratio, markers of inflammation, immunity and the insulin-glucose pathway, lipid profile, and others. Discussion: The goal of this endpoint-blinded, phase III randomised controlled trial is to provide evidence to guide post-stroke physical fitness-based rehabilitation programmes, and to elucidate the mechanisms underlying this intervention. Y1 - 2014 U6 - https://doi.org/10.1186/1745-6215-15-45 SN - 1745-6215 VL - 15 PB - BioMed Central CY - London ER - TY - JOUR A1 - Fischer, Wolfgang A1 - Ristow, Michael T1 - Bericht über die 31. Brandenburgische Botanikertagung vom 23. bis 26. Juni 2000 in Linowsee bei Rheinsberg Y1 - 2002 ER - TY - THES A1 - Fischer, Wolfgang T1 - Gesellschaftliche Öffnung des Unternehmens : Anforderungen an die gesellschaftspolitisch orientierte Führungskraft T2 - Hochschulschriften zum Personalwesen Y1 - 1999 SN - 3-87988-359-9 SN - 0179-325X VL - 24 PB - Hampp CY - München ER - TY - JOUR A1 - Burkart, Michael A1 - Kummer, Volker A1 - Fischer, Wolfgang T1 - Floristische Neu- und Wiederfunde im Gebiet der Unteren Havel Y1 - 1995 ER - TY - JOUR A1 - Fischer, Wolfgang A1 - Kummer, Volker T1 - Ein Beitrag zur Pilzflora der Höllenberge bei Langengrassau Y1 - 1995 ER - TY - JOUR A1 - Fischer, Wolfgang A1 - Kummer, Volker A1 - Pötsch, Joachim T1 - Zur Vegetation des Feuchtgebietes Internationaler Bedeutung (FIB) Untere Havel Y1 - 1994 ER - TY - JOUR A1 - Fischer, Wolfgang A1 - Kummer, Volker T1 - Zur Verbreitung und Soziologie von S colochloa festucacea L : in Nordostdeutschland und seine Unterscheidung von ähnlichen Gräsern nach vegetativen Merkmalen Y1 - 1994 ER - TY - BOOK A1 - Fischer, Wolfgang A1 - Pötsch, Joachim T1 - Berlin und Brandenburg T3 - Botanische Wanderungen in deutschen Ländern : [Die schönsten Exkursionen] Y1 - 1994 VL - 2 PB - Urania-Verl. CY - Leipzig [u.a.] ER -