TY  - JOUR
A1  - Yang, Guang
A1  - Hu, Rongting
A1  - Ding, Hong-ming
A1  - Kochovski, Zdravko
A1  - Mei, Shilin
A1  - Lu, Yan
A1  - Ma, Yu-qiang
A1  - Chen, Guosong
A1  - Jiang, Ming
T1  - CO2-switchable response of protein microtubules
BT  - behaviour and mechanism
JF  - Materials chemistry frontiers
N2  - Recently, we proposed a small molecular inducing ligand strategy to assemble proteins into highly-ordered structures via dual non-covalent interactions, i.e. carbohydrate-protein interaction and dimerization of Rhodamine B. Using this approach, artificial protein microtubules were successfully constructed. In this study, we find that these microtubules exhibit a perfect CO2 responsiveness; assembly and disassembly of these microtubules were nicely controlled by the alternative passage of CO2 and N-2. Upon the injection of CO2, a negative net-charged SBA turns into a neutral or positive net-charged SBA, which elongated, to some extent, the effective distance between SBA and Rhodamine B, resulting in the disassociation of the Rhodamine B dimer. Further experimental and simulation results reveal that the CO2-responsive mechanism differs from that of solubility change of the previously reported CO2-responsive synthetic materials.
Y1  - 2018
U6  - https://doi.org/10.1039/c8qm00245b
SN  - 2052-1537
VL  - 2
IS  - 9
SP  - 1642
EP  - 1646
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  -