TY - JOUR A1 - Jarecki, Jana B. A1 - Tan, Jolene H. A1 - Jenny, Mirjam T1 - A framework for building cognitive process models JF - Psychonomic bulletin & review : a journal of the Psychonomic Society N2 - The termprocess modelis widely used, but rarely agreed upon. This paper proposes a framework for characterizing and building cognitive process models. Process models model not only inputs and outputs but also model the ongoing information transformations at a given level of abstraction. We argue that the following dimensions characterize process models: They have a scope that includes different levels of abstraction. They specify a hypothesized mental information transformation. They make predictions not only for the behavior of interest but also for processes. The models' predictions for the processes can be derived from the input, without reverse inference from the output data. Moreover, the presumed information transformation steps are not contradicting current knowledge of human cognitive capacities. Lastly, process models require a conceptual scope specifying levels of abstraction for the information entering the mind, the proposed mental events, and the behavior of interest. This framework can be used for refining models before testing them or after testing them empirically, and it does not rely on specific modeling paradigms. It can be a guideline for developing cognitive process models. Moreover, the framework can advance currently unresolved debates about which models belong to the category of process models. KW - cognitive process model KW - cognitive model KW - computational model KW - definitions KW - Marr's levels Y1 - 2020 U6 - https://doi.org/10.3758/s13423-020-01747-2 SN - 1069-9384 SN - 1531-5320 VL - 27 IS - 6 SP - 1218 EP - 1229 PB - Springer CY - New York, NY ER - TY - JOUR A1 - Tschorn, Mira A1 - Kuhlmann, Stella Linnea A1 - Rieckmann, Nina A1 - Beer, Katja A1 - Grosse, Laura A1 - Arolt, Volker A1 - Waltenberger, Johannes A1 - Haverkamp, Wilhelm A1 - Müller-Nordhorn, Jacqueline A1 - Hellweg, Rainer A1 - Ströhle, Andreas T1 - Brain-derived neurotrophic factor, depressive symptoms and somatic comorbidity in patients with coronary heart disease JF - Acta Neuropsychiatrica N2 - Objective: Depression and coronary heart disease (CHD) are highly comorbid conditions. Brain-derived neurotrophic factor (BDNF) plays an important role in cardiovascular processes. Depressed patients typically show decreased BDNF concentrations. We analysed the relationship between BDNF and depression in a sample of patients with CHD and additionally distinguished between cognitive-affective and somatic depression symptoms. We also investigated whether BDNF was associated with somatic comorbidity burden, acute coronary syndrome (ACS) or congestive heart failure (CHF). Methods: The following variables were assessed for 225 hospitalised patients with CHD: BDNF concentrations, depression [Patient Health Questionnaire-9 (PHQ-9)], somatic comorbidity (Charlson Comorbidity Index), CHF, ACS, platelet count, smoking status and antidepressant treatment. Results: Regression models revealed that BDNF was not associated with severity of depression. Although depressed patients (PHQ-9 score >7) had significantly lower BDNF concentrations compared to non-depressed patients (p = 0.04), this was not statistically significant after controlling for confounders (p = 0.15). Cognitive-affective symptoms and somatic comorbidity burden each closely missed a statistically significant association with BDNF concentrations (p = 0.08, p = 0.06, respectively). BDNF was reduced in patients with CHF (p = 0.02). There was no covariate-adjusted, significant association between BDNF and ACS. Conclusion: Serum BDNF concentrations are associated with cardiovascular dysfunction. Somatic comorbidities should be considered when investigating the relationship between depression and BDNF. KW - depression KW - BDNF KW - coronary heart disease KW - heart failure KW - somatic comorbidity KW - acute coronary syndrome Y1 - 2020 U6 - https://doi.org/10.1017/neu.2020.31 SN - 1601-5215 SN - 0924-2708 VL - 33 IS - 1 SP - 22 EP - 30 PB - Cambridge Univ. Press CY - Cambridge ER - TY - JOUR A1 - Paoli, Antonio A1 - Moro, Tatiana A1 - Lorenzetti, Silvio A1 - Seiler, Jan A1 - Lüthy, Fabian A1 - Gross, Micah A1 - Roggio, Federico A1 - Chaabene, Helmi A1 - Musumeci, Giuseppe T1 - The “Journal of Functional Morphology and Kinesiology” Journal Club Series BT - Resistance Training JF - Journal of Functional Morphology and Kinesiology N2 - We are glad to introduce the Second Journal Club of Volume Five, Second Issue. This edition is focused on relevant studies published in the last few years in the field of resistance training, chosen by our Editorial Board members and their colleagues. We hope to stimulate your curiosity in this field and to share with you the passion for the sport, seen also from the scientific point of view. The Editorial Board members wish you an inspiring lecture. Y1 - 2020 U6 - https://doi.org/10.3390/jfmk5020025 SN - 2411-5142 VL - 5 IS - 2 SP - 1 EP - 9 PB - MDPI CY - Basel ER - TY - JOUR A1 - Özkan, Ayşegül A1 - Fikri, Figen Beken A1 - Kırkıcı, Bilal A1 - Kliegl, Reinhold A1 - Acartürk, Cengiz T1 - Eye movement control in Turkish sentence reading JF - Quarterly journal of experimental psychology : QJEP / EPS, Experimental Psychology Society N2 - Reading requires the assembly of cognitive processes across a wide spectrum from low-level visual perception to high-level discourse comprehension. One approach of unravelling the dynamics associated with these processes is to determine how eye movements are influenced by the characteristics of the text, in particular which features of the words within the perceptual span maximise the information intake due to foveal, spillover, parafoveal, and predictive processing. One way to test the generalisability of current proposals of such distributed processing is to examine them across different languages. For Turkish, an agglutinative language with a shallow orthography-phonology mapping, we replicate the well-known canonical main effects of frequency and predictability of the fixated word as well as effects of incoming saccade amplitude and fixation location within the word on single-fixation durations with data from 35 adults reading 120 nine-word sentences. Evidence for previously reported effects of the characteristics of neighbouring words and interactions was mixed. There was no evidence for the expected Turkish-specific morphological effect of the number of inflectional suffixes on single-fixation durations. To control for word-selection bias associated with single-fixation durations, we also tested effects on word skipping, single-fixation, and multiple-fixation cases with a base-line category logit model, assuming an increase of difficulty for an increase in the number of fixations. With this model, significant effects of word characteristics and number of inflectional suffixes of foveal word on probabilities of the number of fixations were observed, while the effects of the characteristics of neighbouring words and interactions were mixed. KW - Eye movements KW - reading KW - Turkish Y1 - 2020 U6 - https://doi.org/10.1177/1747021820963310 SN - 1747-0218 SN - 1747-0226 VL - 74 IS - 2 SP - 377 EP - 397 PB - Sage Publ. CY - London ER - TY - JOUR A1 - Negra, Yassine A1 - Chaabene, Helmi A1 - Fernandez-Fernandez, Jaime A1 - Sammoud, Senda A1 - Bouguezzi, Raja A1 - Prieske, Olaf A1 - Granacher, Urs T1 - Short-term plyometric Jump training improves repeated-sprint ability in prepuberal male soccer players JF - Journal of strength and conditioning research : the research journal of the NSCA N2 - This study examined the effects of a short-term (i.e., 8 weeks) combined horizontal and vertical plyometric jump training (PJT) program in combination with regular soccer-specific training as compared with soccer-specific training only on jump and change of direction (CoD) performances, speed, and repeated-sprint ability (RSA) in prepuberal male soccer players. Twenty-four players were recruited and randomly assigned to either a PJT group (PJT(G); n = 13; 12.7 +/- 0.2 years) or an active control group (CONG; n = 11; 12.7 +/- 0.2 years). The outcome measures included tests for the assessment of jump performance (drop jump from 20- to 40-cm height [DJ20 and DJ40] and 3-hop test [THT]), speed (20-m sprint), CoD (T-test), and RSA (20-m repeated shuttle sprint). Data were analyzed using magnitude-based inferences. Within-group analyses revealed large performance improvements in the T-test (d = -1.2), DJ20 (d = 3.7), DJ40 (d = 3.6), THT (d = 0.6), and the RSA(total) (d = -1.6) in the PJT(G). Between-group analyses showed greater performance improvements in the T-test (d = -2.9), 20-m sprint time (d = -2.0), DJ20 (d = 2.4), DJ40 (d = 2.0), THT (d = 1.9), RSA(best) (d = -1.9), and the RSA(total) (d = -1.9) in the PJT(G) compared with CONG. Eight weeks of an in-season PJT in addition to regular soccer-specific training induced larger increases in measures of physical fitness in prepuberal male soccer players compared with regular soccer-specific training only. More specifically, PJT was effective in improving RSA performance. KW - youth KW - stretch-shortening cycle KW - athletic performance KW - soccer Y1 - 2020 U6 - https://doi.org/10.1519/JSC.0000000000002703 SN - 1064-8011 SN - 1533-4287 VL - 34 IS - 11 SP - 3241 EP - 3249 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Engel, Christoph A1 - Timme, Sinika A1 - Glöckner, Andreas T1 - Coherence-based reasoning and order effects in legal judgments JF - Psychology, public policy and law N2 - According to coherence-based models of legal judgment, individuals form coherent mental representations to make sense of the available evidence. In this process, evidence supporting the emerging assessment is accentuated, resulting in coherence effects. Dependent on specific implementations of coherence-based models, in legal tasks both overweighting of evidence that is presented early (a primacy effect) or late (a recency effect) can be predicted. In two studies (N-1 = 221, N-2 = 332), we investigate coherence effects, order effects, and their interrelation in a mock legal case. We manipulate the order in which the evidence is presented, and whether or not individuals are induced to assess provisionally whether they deem the defendant guilty after seeing half of the evidence (leaning). This leaning manipulation should increase primacy effects. We consistently observed recency effects and no stronger influence of primacy effects when people indicate a leaning. Order and leaning did not influence the magnitude of coherence effects. In contrast to previous findings in consumer research and risky choice tasks, coherence effects did not mediate the effect of the order in which the evidence in legal judgments is presented. If our results hold more generally, coherence-based models of legal judgment might have to be revised to give more weight to recency effects as compared to the typically predicted primacy effects. This revision would have implications for the design of criminal procedure. KW - legal judgment KW - coherence effects KW - primacy and recency effects KW - order KW - effects KW - leaning Y1 - 2020 U6 - https://doi.org/10.1037/law0000257 SN - 1076-8971 SN - 1939-1528 VL - 26 IS - 3 SP - 333 EP - 352 PB - American Psychological Association CY - Washington ER - TY - JOUR A1 - Nevill, Alan M. A1 - Negra, Yassine A1 - Myers, Tony D. A1 - Sammoud, Senda A1 - Chaabene, Helmi T1 - Key somatic variables associated with, and differences between the 4 swimming strokes JF - Journal of sports sciences N2 - This study identified key somatic and demographic characteristics that benefit all swimmers and, at the same time, identified further characteristics that benefit only specific swimming strokes. Three hundred sixty-three competitive-level swimmers (male [n = 202]; female [n = 161]) participated in the study. We adopted a multiplicative, allometric regression model to identify the key characteristics associated with 100 m swimming speeds (controlling for age). The model was refined using backward elimination. Characteristics that benefited some but not all strokes were identified by introducing stroke-by-predictor variable interactions. The regression analysis revealed 7 "common" characteristics that benefited all swimmers suggesting that all swimmers benefit from having less body fat, broad shoulders and hips, a greater arm span (but shorter lower arms) and greater forearm girths with smaller relaxed arm girths. The 4 stroke-specific characteristics reveal that backstroke swimmers benefit from longer backs, a finding that can be likened to boats with longer hulls also travel faster through the water. Other stroke-by-predictor variable interactions (taken together) identified that butterfly swimmers are characterized by greater muscularity in the lower legs. These results highlight the importance of considering somatic and demographic characteristics of young swimmers for talent identification purposes (i.e., to ensure that swimmers realize their most appropriate strokes). KW - swim speed KW - talent identification KW - limb dimensions KW - ratios KW - allometric KW - models KW - log-linear regression Y1 - 2020 U6 - https://doi.org/10.1080/02640414.2020.1734311 SN - 0264-0414 SN - 1466-447X VL - 38 IS - 7 SP - 787 EP - 794 PB - Routledge, Taylor & Francis Group CY - London ER - TY - JOUR A1 - Chen, Ke A1 - Hollunder, Barbara A1 - Garbusow, Maria A1 - Sebold, Miriam Hannah A1 - Heinz, Andreas T1 - The physiological responses to acute stress in alcohol-dependent patients BT - a systematic review JF - European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology N2 - Dysregulation of physiological stress reactivity plays a key role in the development and relapse risk of alcohol dependence. This article reviews studies investigating physiological responses to experimentally induced acute stress in patients with alcohol dependence. A systematic search from electronic databases resulted in 3641 articles found and after screening 62 articles were included in our review. Studies are analyzed based on stress types (i.e., social stress tasks and nonsocial stress tasks) and physiological markers (i.e., the nervous system, the endocrine system, somatic responses and the immune system). In studies applying nonsocial stress tasks, alcohol-dependent patients were reported to show a blunted stress response compared with healthy controls in the majority of studies applying markers of adrenocorticotropic hormone and cortisol. In studies applying social stress tasks, findings are inconsistent, with less than half of the studies reporting altered physiological stress responses in patients. We discuss the impact of duration of abstinence, comorbidities, baseline physiological arousal and intervention on the discrepancy of study findings. Furthermore, we review evidence for an associationbetween blunted physiological stress responses and the relapse risk among patients with alcohol dependence. (c) 2020 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) KW - acute stress KW - alcohol dependence KW - hypothalamic- pituitary-adrenal axis KW - physiological reactivity Y1 - 2020 U6 - https://doi.org/10.1016/j.euroneuro.2020.09.003 SN - 0924-977X SN - 1873-7862 VL - 41 SP - 1 EP - 15 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Prieske, Olaf A1 - Chaabene, Helmi A1 - Gäbler, Martijn A1 - Herz, Michael A1 - Helm, Norman A1 - Markov, Adrian A1 - Granacher, Urs T1 - Seasonal changes in anthropometry, body composition, and physical fitness and the relationships with sporting success in young sub-elite judo athletes BT - an exploratory study JF - International journal of environmental research and public health : IJERPH N2 - This exploratory study aimed to monitor long-term seasonal developments in measures of anthropometry, body composition, and physical fitness in young judo athletes, and to compute associations between these measures and sporting success. Forty-four young judoka (20 females, 24 males) volunteered to participate. Tests for the assessment of anthropometry (e.g., body height/mass), body-composition (e.g., lean body mass), muscle strength (isometric handgrip strength), vertical jumping (e.g., countermovement-jump (CMJ) height), and dynamic balance (Y-balance test) were conducted at the beginning and end of a 10-month training season. Additionally, sporting success at the end of the season was recorded for each athlete. Analyses revealed significant time x sex interaction effects for lean-body-mass, isometric handgrip strength, and CMJ height (0.7 <= d <= 1.6). Post-hoc analyses showed larger gains for all measures in young males (1.9 <= d <= 6.0) compared with females (d = 2.4) across the season. Additionally, significant increases in body height and mass as well as Y-balance test scores were found from pre-to-post-test (1.2 <= d <= 4.3), irrespective of sex. Further, non-significant small-to-moderate-sized correlations were identified between changes in anthropometry/body composition/physical fitness and sporting success (p > 0.05; -0.34 <= rho <= 0.32). Regression analysis confirmed that no model significantly predicted sporting success. Ten months of judo training and/or growth/maturation contributed to significant changes in anthropometry, body composition, and physical fitness, particularly in young male judo athletes. KW - combat sports KW - periodization KW - somatic variables KW - training load KW - training KW - monitoring KW - young athletes Y1 - 2020 U6 - https://doi.org/10.3390/ijerph17197169 SN - 1660-4601 VL - 17 IS - 19 PB - MDPI AG CY - Basel ER - TY - JOUR A1 - Negra, Yassine A1 - Chaabene, Helmi A1 - Sammoud, Senda A1 - Prieske, Olaf A1 - Moran, Jason A1 - Ramirez-Campillo, Rodrigo A1 - Nejmaoui, Ali A1 - Granacher, Urs T1 - The increased effectiveness of loaded versus unloaded plyometric jump training in improving muscle power, speed, change of direction, and kicking-distance performance in prepubertal male soccer players JF - International journal of sports physiology and performance : IJSSP N2 - Purpose: To examine the effects of loaded (LPJT) versus unloaded plyometric jump training (UPJT) programs on measures of muscle power, speed, change of direction (CoD), and kicking-distance performance in prepubertal male soccer players. Methods: Participants (N = 29) were randomly assigned to a LPJT group (n = 13; age = 13.0 [0.7] y) using weighted vests or UPJT group (n = 16; age = 13.0 [0.5] y) using body mass only. Before and after the intervention, tests for the assessment of proxies of muscle power (ie, countermovement jump, standing long jump); speed (ie, 5-, 10-, and 20-m sprint); CoD (ie, Illinois CoD test, modified 505 agility test); and kicking-distance were conducted. Data were analyzed using magnitude-based inferences. Results: Within-group analyses for the LPJT group showed large and very large improvements for 10-m sprint time (effect size [ES] = 2.00) and modified 505 CoD (ES = 2.83) tests, respectively. For the same group, moderate improvements were observed for the Illinois CoD test (ES = 0.61), 5- and 20-m sprint time test (ES = 1.00 for both the tests), countermovement jump test (ES = 1.00), and the maximal kicking-distance test (ES = 0.90). Small enhancements in the standing long jump test (ES = 0.50) were apparent. Regarding the UPJT group, small improvements were observed for all tests (ES = 0.33-0.57), except 5- and 10-m sprint time (ES = 1.00 and 0.63, respectively). Between-group analyses favored the LPJT group for the modified 505 CoD (ES = 0.61), standing long jump (ES = 0.50), and maximal kicking-distance tests (ES = 0.57), but not for the 5-m sprint time test (ES = 1.00). Only trivial between-group differences were shown for the remaining tests (ES = 0.00-0.09). Conclusion: Overall, LPJT appears to be more effective than UPJT in improving measures of muscle power, speed, CoD, and kicking-distance performance in prepubertal male soccer players. KW - young KW - football KW - stretch-shortening cycle KW - maturity KW - athletic KW - performance Y1 - 2020 U6 - https://doi.org/10.1123/ijspp.2018-0866 SN - 1555-0265 SN - 1555-0273 VL - 15 IS - 2 SP - 189 EP - 195 PB - Human Kinetics CY - Champaign, Ill. ER - TY - JOUR A1 - Moran, Jason A1 - Paxton, Kevin A1 - Jones, Ben A1 - Granacher, Urs A1 - Sandercock, Gavin Rh A1 - Hope, Edward A1 - Ramirez-Campillo, Rodrigo T1 - Variable long-term developmental trajectories of short sprint speed and jumping height in English Premier League academy soccer players: an applied case study JF - Journal of sports sciences N2 - Growth and maturation affect long term physical performance, making the appraisal of athletic ability difficult. We sought to longitudinally track youth soccer players to assess the developmental trajectory of athletic performance over a 6-year period in an English Premier League academy. Age-specific z-scores were calculated for sprint and jump performance from a sample of male youth soccer players (n = 140). A case study approach was used to analyse the longitudinal curves of the six players with the longest tenure. The trajectories of the sprint times of players 1 and 3 were characterised by a marked difference in respective performance levels up until peak height velocity (PHV) when player 1 achieved a substantial increase in sprint speed and player 3 experienced a large decrease. Player 5 was consistently a better performer than player 2 until PHV when the sprint and jump performance of the former markedly decreased and he was overtaken by the latter. Fluctuations in players' physical performance can occur quickly and in drastic fashion. Coaches must be aware that suppressed, or inflated, performance could be temporary and selection and deselection decisions should not be made based on information gathered over a short time period. KW - youth KW - football KW - talent KW - running velocity KW - muscular power Y1 - 2020 U6 - https://doi.org/10.1080/02640414.2020.1792689 SN - 0264-0414 SN - 1466-447X VL - 38 IS - 22 SP - 2525 EP - 2531 PB - Routledge, Taylor & Francis Group CY - London ER - TY - JOUR A1 - Chaabene, Helmi A1 - Prieske, Olaf A1 - Moran, Jason A1 - Negra, Yassine A1 - Attia, Ahmed A1 - Granacher, Urs T1 - Effects of resistance training on Change-of-Direction speed in youth and young physically active and athletic adults: a systematic review with meta-analysis JF - Sports medicine : the world's premier sports medicine preview journal N2 - Background Change-of-direction (CoD) speed is a physical fitness attribute in many field-based team and individual sports. To date, no systematic review with meta-analysis available has examined the effects of resistance training (RT) on CoD speed in youth and adults. Objective To aggregate the effects of RT on CoD speed in youth and young physically active and athletic adults, and to identify the key RT programme variables for training prescription. Data sources A systematic literature search was conducted with PubMed, Web of Science, and Google Scholar, with no date restrictions, up to October 2019, to identify studies related to the effects of RT on CoD speed. Study Eligibility Criteria Only controlled studies with baseline and follow-up measures were included if they examined the effects of RT (i.e., muscle actions against external resistances) on CoD speed in healthy youth (8-18 years) and young physically active/athletic male or female adults (19-28 years). Study Appraisal and Synthesis Methods A random-effects model was used to calculate weighted standardised mean differences (SMD) between intervention and control groups. In addition, an independent single training factor analysis (i.e., RT frequency, intensity, volume) was undertaken. Further, to verify if any RT variable moderated effects on CoD speed, a multivariate random-effects meta-regression was conducted. The methodological quality of the included studies was assessed using the physiotherapy evidence database (PEDro) scale. Results Fifteen studies, comprising 19 experimental groups, were included. The methodological quality of the studies was acceptable with a median PEDro score of 6. There was a significant large effect size of RT on CoD speed across all studies (SMD = - 0.82 [- 1.14 to - 0.49]). Subgroup analyses showed large effect sizes on CoD speed in males (SMD = - 0.95) contrasting with moderate improvements in females (SMD = - 0.60). There were large effect sizes on CoD speed in children (SMD = - 1.28) and adolescents (SMD = - 1.21) contrasting with moderate effects in adults (SMD = - 0.63). There was a moderate effect in elite athletes (SMD = - 0.69) contrasting with a large effect in subelite athletes (SMD = - 0.86). Differences between subgroups were not statistically significant. Similar improvements were observed regarding the effects of independently computed training variables. In terms of RT frequency, our results indicated that two sessions per week induced large effects on CoD speed (SMD = - 1.07) while programmes with three sessions resulted in moderate effects (SMD = - 0.53). For total training intervention duration, we observed large effects for <= 8 weeks (SMD = - 0.81) and > 8 weeks (SMD = - 0.85). For single session duration, we found large effects for <= 30 min and >= 45 min (both SMD = - 1.00). In terms of number of training sessions, we identified large effects for <= 16 sessions (SMD = - 0.83) and > 16 sessions (SMD = - 0.81). For training intensity, we found moderate effects for light-to-moderate (SMD = - 0.76) and vigorous-to-near maximal intensities (SMD = - 0.77). With regards to RT type, we observed large effects for free weights (SMD = - 0.99) and machine-based training (SMD = - 0.80). For combined free weights and machine-based training, moderate effects were identified (SMD = - 0.77). The meta-regression outcomes showed that none of the included training variables significantly predicted the effects of RT on CoD speed (R-2 = 0.00). Conclusions RT seems to be an effective means to improve CoD speed in youth and young physically active and athletic adults. Our findings indicate that the impact of RT on CoD speed may be more prominent in males than in females and in youth than in adults. Additionally, independently computed single factor analyses for different training variables showed that higher compared with lower RT intensities, frequencies, and volumes appear not to have an advantage on the magnitude of CoD speed improvements. In terms of RT type, similar improvements were observed following machine-based and free weights training. Y1 - 2020 U6 - https://doi.org/10.1007/s40279-020-01293-w SN - 0112-1642 SN - 1179-2035 VL - 50 IS - 8 SP - 1483 EP - 1499 PB - Springer CY - Berlin [u.a.] ER - TY - JOUR A1 - Georgiou, Iakovos A1 - Kruppa, Philipp A1 - Schmidt, Jeremias A1 - Ghods, Mojtaba T1 - Liposuction for Lipoedema BT - functional therapy or aesthetic procedure? JF - Aesthetic plastic surgery : official journal of the International Society of Aesthetic Plastic Surgery ; official publication of the Lipoplasty Society of North America N2 - Liposuction is one of the most common procedures undertaken in plastic surgery with a steadily increasing trend over the years. Although usually performed as an aesthetic procedure for body contouring, it can also be utilized in specific patient groups for disease symptom reduction. One such disease entity is lipedema. The goal of this video to present the authors' technique in the surgical treatment of lipedema, and to offer the viewer a better understanding of the differences between an aesthetic liposuction and a functional liposuction as performed on a lipedema patient. Between July 2009 and July 2019, 106 lipedema patients have been treated in the authors' specialized lipedema clinic, with a total of 298 liposuction procedures and a median follow-up of 20 months. The mean amount of lipoaspirate was 6354.73 ml (+/- 2796.72 ml). The patients reported a significant reduction in lipedema-associated complaints and improvement in quality of life. The need for conservative therapy was significantly reduced. No serious complications were reported. The authors also present before and after photographs of three patients. KW - Lipedema KW - Lipoedema KW - Liposuction KW - Megaliposuction Y1 - 2020 U6 - https://doi.org/10.1007/s00266-020-01910-z SN - 0364-216X SN - 1432-5241 VL - 45 SP - 212 EP - 213 PB - Springer CY - New York ER - TY - JOUR A1 - Prieske, Olaf A1 - Behrens, Martin A1 - Chaabene, Helmi A1 - Granacher, Urs A1 - Maffiuletti, Nicola A. T1 - Time to differentiate postactivation "potentiation" from "performance enhancement" in the strength and conditioning community JF - Sports medicine : the world's premier sports medicine preview journal N2 - Coaches and athletes in elite sports are constantly seeking to use innovative and advanced training strategies to efficiently improve strength/power performance in already highly-trained individuals. In this regard, high-intensity conditioning contractions have become a popular means to induce acute improvements primarily in muscle contractile properties, which are supposed to translate to subsequent power performances. This performance-enhancing physiological mechanism has previously been called postactivation potentiation (PAP). However, in contrast to the traditional mechanistic understanding of PAP that is based on electrically-evoked twitch properties, an increasing number of studies used the term PAP while referring to acute performance enhancements, even if physiological measures of PAP were not directly assessed. In this current opinion article, we compare the two main approaches (i.e., mechanistic vs. performance) used in the literature to describe PAP effects. We additionally discuss potential misconceptions in the general use of the term PAP. Studies showed that mechanistic and performance-related PAP approaches have different characteristics in terms of the applied research field (basic vs. applied), effective conditioning contractions (e.g., stimulated vs. voluntary), verification (lab-based vs. field tests), effects (twitch peak force vs. maximal voluntary strength), occurrence (consistent vs. inconsistent), and time course (largest effect immediately after vs. similar to 7 min after the conditioning contraction). Moreover, cross-sectional studies revealed inconsistent and trivial-to-large-sized associations between selected measures of mechanistic (e.g., twitch peak force) vs. performance-related PAP approaches (e.g., jump height). In an attempt to avoid misconceptions related to the two different PAP approaches, we propose to use two different terms. Postactivation potentiation should only be used to indicate the increase in muscular force/torque production during an electrically-evoked twitch. In contrast, postactivation performance enhancement (PAPE) should be used to refer to the enhancement of measures of maximal strength, power, and speed following conditioning contractions. The implementation of this terminology would help to better differentiate between mechanistic and performance-related PAP approaches. This is important from a physiological point of view, but also when it comes to aggregating findings from PAP studies, e.g., in the form of meta-analyses, and translating these findings to the field of strength and conditioning. Y1 - 2020 U6 - https://doi.org/10.1007/s40279-020-01300-0 SN - 0112-1642 SN - 1179-2035 VL - 50 IS - 9 SP - 1559 EP - 1565 PB - Springer CY - Berlin [u.a.] ER - TY - JOUR A1 - Azadian, Elaheh A1 - Majlesi, Mahdi A1 - Jafarnezhadgero, Amir Ali A1 - Granacher, Urs T1 - The impact of hearing loss on three-dimensional lower limb joint torques during walking in prepubertal boys JF - Journal of bodywork and movement therapies N2 - Introduction: In children, the impact of hearing loss on biomechanical gait parameters is not well understood. Thus, the objectives of this study were to examine three-dimensional lower limb joint torques in deaf compared to age-matched healthy (hearing) children while walking at preferred gait speed. Methods: Thirty prepubertal boys aged 8-14 were enrolled in this study and divided into a group with hearing loss (deaf group) and an age-matched healthy control. Three-dimensional joint torques were analyzed during barefoot walking at preferred speed using Kistler force plates and a Vicon motion capture system. Results: Findings revealed that boys with hearing loss showed lower joint torques in ankle evertors, knee flexors, abductors and internal rotators as well as in hip internal rotators in both, the dominant and non-dominant lower limbs (all p < 0.05; d = 1.23-7.00; 14-79%). Further, in the dominant limb, larger peak ankle dorsiflexor (p < 0.001; d = 1.83; 129%), knee adductor (p < 0.001; d = 3.20; 800%), and hip adductor torques (p < 0.001; d = 2.62; 350%) were found in deaf participants compared with controls. Conclusion: The observed altered lower limb torques during walking are indicative of unstable gait in children with hearing loss. More research is needed to elucidate whether physical training (e.g., balance and/or gait training) has the potential to improve walking performance in this patient group. (C) 2019 Elsevier Ltd. All rights reserved. KW - torque KW - hearing loss KW - gait KW - dominant limb KW - non-dominant limb Y1 - 2020 U6 - https://doi.org/10.1016/j.jbmt.2019.10.013 SN - 1360-8592 SN - 1532-9283 VL - 24 IS - 2 SP - 123 EP - 129 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Sallen, Jeffrey A1 - Andrä, Christian A1 - Ludyga, Sebastian A1 - Mücke, Manuel A1 - Herrmann, Christian T1 - School children's physical activity, motor competence, and corresponding self-perception BT - a longitudinal analysis of reciprocal relationships JF - Journal of physical activity and health N2 - Background: The relationship between engagement in physical activity and the development of motor competence (MC) is considered to be reciprocal and dynamic throughout childhood and adolescence. The 10-month follow-up study aimed to explore this reciprocal relationship and investigated whether the relationship is mediated by the corresponding self-perception of MC (PMC). Methods: A total of 51 children aged between 10 and 11 years (M = 10.27 [0.45]) participated in the study (52.9% boys, 47.1% girls). As an indicator for physical activity, the average vigorous physical activity (VPA) per day was measured by ActiGraph accelerometers. Two aspects of MC and PMC were recorded: self-movement and object movement. Saturated pathway models in a cross-lagged panel design with 2 measurement points were analyzed. Results: Reciprocal and direct relationships between VPA and MC object movement respectively MC self-movement were not found in longitudinal analyses with PMC as a mediator. Indirect effects of MC at t1 on VPA at t2 via PMC were identified (self-movement: beta = 0.13, 95% confidence interval, 0.04 to 0.26; object movement: beta = 0.14, 95% confidence interval, 0.01 to 0.49). Conclusion: The results highlight the importance of MC and PMC in promoting children's VPA. However, VPA does not drive the development of MC. KW - MOBAK KW - SEMOK KW - fundamental movement skills KW - motor proficiency Y1 - 2020 U6 - https://doi.org/10.1123/jpah.2019-0507 SN - 1543-3080 SN - 1543-5474 VL - 17 IS - 11 SP - 1083 EP - 1090 PB - Human Kinetics Publ. CY - Champaign ER - TY - JOUR A1 - Herzog, Stefan M. A1 - Jenny, Mirjam A. A1 - Nickel, Christian A1 - Ortega, Ricardo Nieves A1 - Bingisser, Roland T1 - Emergency department patients with weakness or fatigue BT - can physicians predict their outcomes at the front door? A prospective observational study JF - PLOS ONE N2 - Background Generalized weakness and fatigue are underexplored symptoms in emergency medicine. Triage tools often underestimate patients presenting to the emergency department (ED) with these nonspecific symptoms (Nemec et al., 2010). At the same time, physicians' disease severity rating (DSR) on a scale from 0 (not sick at all) to 10 (extremely sick) predicts key outcomes in ED patients (Beglinger et al., 2015; Rohacek et al., 2015). Our goals were (1) to characterize ED patients with weakness and/or fatigue (W|F); to explore (2) to what extent physicians' DSR at triage can predict five key outcomes in ED patients with W|F; (3) how well DSR performs relative to two commonly used benchmark methods, the Emergency Severity Index (ESI) and the Charlson Comorbidity Index (CCI); (4) to what extent DSR provides predictive information beyond ESI, CCI, or their linear combination, i.e., whether ESI and CCI should be used alone or in combination with DSR; and (5) to what extent ESI, CCI, or their linear combination provide predictive information beyond DSR alone, i.e., whether DSR should be used alone or in combination with ESI and / or CCI. Methods Prospective observational study between 2013-2015 (analysis in 2018-2020, study team blinded to hypothesis) conducted at a single center. We study an all-comer cohort of 3,960 patients (48% female patients, median age = 51 years, 94% completed 1-year follow-up). We looked at two primary outcomes (acute morbidity (Bingisser et al., 2017; Weigel et al., 2017) and all-cause 1- year mortality) and three secondary outcomes (in-hospital mortality, hospitalization and transfer to ICU). We assessed the predictive power (i.e., resolution, measured as the Area under the ROC Curve, AUC) of the scores and, using logistic regression, their linear combinations. Findings Compared to patients without W|F (n = 3,227), patients with W|F (n = 733) showed higher prevalences for all five outcomes, reported more symptoms across both genders, and received higher DSRs (median = 4; interquartile range (IQR) = 3-6 vs. median = 3; IQR = 2-5). DSR predicted all five outcomes well above chance (i.e., AUCs > similar to 0.70), similarly well for both patients with and without W|F, and as good as or better than ESI and CCI in patients with and without W|F (except for 1-year mortality where CCI performs better). For acute morbidity, hospitalization, and transfer to ICU there is clear evidence that adding DSR to ESI and/or CCI improves predictions for both patient groups; for 1-year mortality and in-hospital mortality this holds for most, but not all comparisons. Adding ESI and/or CCI to DSR generally did not improve performance or even decreased it. Conclusions The use of physicians' disease severity rating has never been investigated in patients with generalized weakness and fatigue. We show that physicians' prediction of acute morbidity, mortality, hospitalization, and transfer to ICU through their DSR is also accurate in these patients. Across all patients, DSR is less predictive of acute morbidity for female than male patients, however. Future research should investigate how emergency physicians judge their patients' clinical state at triage and how this can be improved and used in simple decision aids. Y1 - 2020 U6 - https://doi.org/10.1371/journal.pone.0239902 SN - 1932-6203 VL - 15 IS - 11 PB - Public Library of Science CY - San Francisco, California, US ER - TY - JOUR A1 - Schwaab, Bernhard A1 - Rauch, Bernhard A1 - Völler, Heinz A1 - Benzer, Werner A1 - Schmid, Jean-Paul T1 - Beyond randomised studies BT - recommendations for cardiac rehabilitation following repair of thoracic aortic aneurysm or dissection JF - European journal of preventive cardiology : the official ESC journal for primary & secondary cardiovascular prevention, rehabilitation and sports cardiology Y1 - 2020 U6 - https://doi.org/10.1177/2047487320936782 SN - 2047-4873 SN - 2047-4881 VL - 28 IS - 17 SP - E17 EP - E19 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Dondapati, Srujan Kumar A1 - Stech, Marlitt A1 - Zemella, Anne A1 - Kubick, Stefan T1 - Cell-free protein synthesis BT - a promising option for future drug development JF - BioDrugs N2 - Proteins are the main source of drug targets and some of them possess therapeutic potential themselves. Among them, membrane proteins constitute approximately 50% of the major drug targets. In the drug discovery pipeline, rapid methods for producing different classes of proteins in a simple manner with high quality are important for structural and functional analysis. Cell-free systems are emerging as an attractive alternative for the production of proteins due to their flexible nature without any cell membrane constraints. In a bioproduction context, open systems based on cell lysates derived from different sources, and with batch-to-batch consistency, have acted as a catalyst for cell-free synthesis of target proteins. Most importantly, proteins can be processed for downstream applications like purification and functional analysis without the necessity of transfection, selection, and expansion of clones. In the last 5 years, there has been an increased availability of new cell-free lysates derived from multiple organisms, and their use for the synthesis of a diverse range of proteins. Despite this progress, major challenges still exist in terms of scalability, cost effectiveness, protein folding, and functionality. In this review, we present an overview of different cell-free systems derived from diverse sources and their application in the production of a wide spectrum of proteins. Further, this article discusses some recent progress in cell-free systems derived from Chinese hamster ovary and Sf21 lysates containing endogenous translocationally active microsomes for the synthesis of membrane proteins. We particularly highlight the usage of internal ribosomal entry site sequences for more efficient protein production, and also the significance of site-specific incorporation of non-canonical amino acids for labeling applications and creation of antibody drug conjugates using cell-free systems. We also discuss strategies to overcome the major challenges involved in commercializing cell-free platforms from a laboratory level for future drug development. Y1 - 2020 U6 - https://doi.org/10.1007/s40259-020-00417-y SN - 1173-8804 SN - 1179-190X VL - 34 IS - 3 SP - 327 EP - 348 PB - Springer CY - Northcote ER - TY - JOUR A1 - Trounson, Karl M. A1 - Busch, Aglaja A1 - Collier, Neil French A1 - Robertson, Samuel T1 - Effects of acute wearable resistance loading on overground running lower body kinematics JF - PLoS one N2 - Field-based sports require athletes to run sub-maximally over significant distances, often while contending with dynamic perturbations to preferred coordination patterns. The ability to adapt movement to maintain performance under such perturbations appears to be trainable through exposure to task variability, which encourages movement variability. The aim of the present study was to investigate the extent to which various wearable resistance loading magnitudes alter coordination and induce movement variability during running. To investigate this, 14 participants (three female and 11 male) performed 10 sub-maximal velocity shuttle runs with either no weight, 1%, 3%, or 5% of body weight attached to the lower limbs. Sagittal plane lower limb joint kinematics from one complete stride cycle in each run were assessed using functional data analysis techniques, both across the participant group and within-individuals. At the group-level, decreases in ankle plantarflexion following toe-off were evident in the 3% and 5% conditions, while increased knee flexion occurred during weight acceptance in the 5% condition compared with unloaded running. At the individual-level, between-run joint angle profiles varied, with six participants exhibiting increased joint angle variability in one or more loading conditions compared with unloaded running. Loading of 5% decreased between-run ankle joint variability among two individuals, likely in accordance with the need to manage increased system load or the novelty of the task. In terms of joint coordination, the most considerable alterations to coordination occurred in the 5% loading condition at the hip-knee joint pair, however, only a minority of participants exhibited this tendency. Coaches should prescribe wearable resistance individually to perturb preferred coordination patterns and encourage movement variability without loading to the extent that movement options become limited. KW - movement patterns KW - external perturbations KW - australian football KW - performance KW - variability KW - coordination KW - freedom KW - leg KW - identification KW - adaptations Y1 - 2020 U6 - https://doi.org/10.1371/journal.pone.0244361 SN - 1932-6203 VL - 15 IS - 12 PB - PLoS CY - San Francisco, California, US ER - TY - JOUR A1 - Reibis, Rona K. A1 - Völler, Heinz T1 - Non pharmacological secondary prevention and rehabilitation T1 - Nicht pharmakologische Sekundärprävention und Rehabilitation BT - current evidence BT - aktuelle Evidenz JF - Aktuelle Kardiologie N2 - Die Sekundärprävention der koronaren Herzkrankheit umfasst einerseits eine pharmakologische, andererseits eine lebensstilbasierte Säule, die idealerweise interagieren und sich potenzieren. Neben der medikamentösen Blutdruck- und Lipideinstellung auf leitlinienorientierte Zielwerte ermöglichen moderne Antidiabetika eine Optimierung des glukometabolischen Kontinuums und eine Prognosebesserung. Die Lebensstiloptimierung setzt sich aus koronarprotektiver Ernährung, einer individualisierten Trainingstherapie, einer konsequenten Nikotinkarenz und stressreduzierenden Maßnahmen zusammen. Die kardiologische Rehabilitation (Phase II) schließt sich idealerweise unmittelbar einem stationären Aufenthalt wegen eines akuten Koronarereignisses an, kann aber auch im Rahmen einer stabilen Koronarsituation im Rahmen eines allgemeinen Antragsverfahrens durchgeführt werden. Randomisierte und prospektiv angelegte Interventionsstudien belegen die prognostische Wertigkeit der kardiologischen Rehabilitation auch im Zeitalter akuter Revaskularisationstherapie mit 24-h-PCI und moderner Pharmakotherapie. N2 - Secondary prevention of coronary artery disease includes pharmacological and lifestyle-based therapy that ideally interact and potentiate. In addition to blood pressure and lipid adjustment to guideline-oriented target values, modern antidiabetic agents enable an optimization of the glucometabolic continuum and improve prognosis. Lifestyle optimization consists of coronary protective nutrition, individualized training therapy, consistent nicotine withdrawal and stress-reducing measures. Cardiological rehabilitation (phase II) ideally immediately follows an inpatient stay due to an acute coronary event, but can also be carried out in the context of a stable coronary situation. Randomized and prospective intervention studies prove the prognostic value of cardiological rehabilitation even in the age of acute revascularization therapy with 24-hour PCI and modern pharmacotherapy. KW - cardiac rehabilitation KW - physical activity KW - nutrition KW - professional KW - reintegration KW - secondary prevention KW - Sekundärprävention KW - kardiologische Rehabilitation KW - Trainingstherapie KW - Ernährung KW - berufliche Wiedereingliederung Y1 - 2020 U6 - https://doi.org/10.1055/a-1185-8460 SN - 2193-5203 SN - 2193-5211 VL - 9 IS - 03 SP - 297 EP - 302 PB - Thieme CY - Stuttgart ER - TY - JOUR A1 - Kellis, Eleftherios A1 - Ellinoudis, Athanasios A1 - Intziegianni, Konstantina A1 - Kofotolis, Nikolaos T1 - Muscle thickness during core stability exercises in children and adults JF - Journal of human kinetics N2 - Core stability exercises are regular part of exercise programs for asymptomatic individuals across ages. The purpose of this study was to examine deep abdominal and multifidus muscle thickness in children and adults and to determine reliability of the rehabilitative ultrasound (RUSI) imaging. Transversus abdominis and lumbar multifidus thickness at rest and during core stability exercise were examined in pre-pubertal children (N = 23), adolescents (N = 20), young adults (N = 21) and middle-aged adults (N = 22). Thirty-nine participants were re-tested one week after to establish reliability. Muscle thickness at rest was lower in children and adolescents compared with young and middle-aged adults (p < 0.008). Young adults displayed the highest relative transversus abdominis thickness upon contraction (p < 0.008). Lumbar multfidus contraction thickness was greater in young-adults than middle-aged adults and prepubertal children (p < 0.008), but it was similar between young-adults and adolescents (p > 0.008). Reliability was high for both muscles (ICC3,3 = 0.76 - 0.99). The age-related differences in muscle thickness indicate that core stability exercises may be beneficial for children and middle-aged adults. KW - childhood KW - musculoskeletal ultrasound KW - repeatability KW - core exercise KW - core stability Y1 - 2020 U6 - https://doi.org/10.2478/hukin-2019-0079 SN - 1640-5544 SN - 1899-7562 VL - 71 IS - 1 SP - 131 EP - 144 PB - Academy of Physical Education CY - Katowice ER - TY - JOUR A1 - Helm, Norman A1 - Prieske, Olaf A1 - Mühlbauer, Thomas A1 - Krüger, Tom A1 - Retzlaff, Matthias A1 - Granacher, Urs T1 - Associations between trunk muscle strength and judo-specific pulling performances in judo athletes T1 - Assoziationen zwischen der Rumpfkraft und judospezifischen Anriss-Leistungen von Judoka JF - Sportverletzung, Sportschaden : Grundlagen, Prävention, Rehabilitation N2 - Background: Good trunk stability is an important prerequisite for the mobility of the upper and lower limbs during sport-specific movements. Therefore, trunk muscle strength may represent an important performance determinant for judo-specific movements. This study aimed at evaluating statistical correlations between trunk muscle strength and kinetic parameters during judo-specific pulling movements in judo players. Method: Twenty-one male sub-elite judo players aged 22 +/- 4 years with a mean training volume of 15 +/- 4 hours per week participated in this study. Peak isokinetic torque (PIT) of the trunk flexors (PITFlex), extensors (PITEx) and rotators (PITRot) was tested using an isokinetic dynamometer (IsoMed 2000). In addition, two kinetic parameters (mechanical work [W], maximal force [F-max]) were analysed using the judo-specific measurement and information system JERGo (c). For this purpose, athletes were asked to do their judo-specific pulling movements while standing and with a dynamic change of position (i.e. Morote-seoi-nage). Results: Regarding pulling movements while standing, significant correlations (0.62 <= r(P) <= 0.72) were found between isokinetic tests (PITFlex, PITEx, PITRot) and mechanical work during judo-specific movement. Further, significant correlations (0.59 <= r(P) <= 0.65) were detected between isokinetic tests (PITEx, PITRot) and judo-specific pulling movements (Fmax). Regarding pulling movements with a change of position, significant correlations (0.47 <= r(P) <= 0.88) were observed between isokinetics (PITFlex, PITEx, PITRot) and the kinetic pulling parameters (W, Fmax), irrespective of the examined arm. No significant differences in magnitude of correlation coefficients were found between PIT of the trunk flexors, extensors, and rotators and judo-specific movements. Further, the regression analysis indicated that PIT of the trunk extensors is the single best predictor for mechanical work during pulling movements while standing (46.9 %). Trunk rotator PIT is the single best predictor for mechanical work during pulling movements with a change of position (69.4 %). Conclusions: Findings from this study indicate that trunk muscle strength, particularly trunk rotator PIT is associated with kinetic pulling variables during pulling movements with a change of position. This implies that the development of trunk rotator strength could have an impact on pulling movements with a change of position (i.e. Morote-seoi-nage) in judo athletes. N2 - Hintergrund: Eine gut ausgeprägte Rumpfstabilität ist eine wichtige Voraussetzung für die Mobilität der oberen und unteren Extremitäten während des sportlichen Bewegungsvollzugs. Vor diesem Hintergrund könnte die Rumpfkraft ein leistungsdeterminierender Faktor bei der Ausführung judospezifischer Bewegungen darstellen. Das Ziel der vorliegenden Studie war es, statistische Zusammenhänge zwischen der Rumpfkraft und kinetischen Parametern bei Anriss-Bewegungen von Judoka zu untersuchen. Methode: An der Untersuchung nahmen 21 leistungsorientierte Judoka mit einem mittleren Alter von 22 ± 4 Jahre und einem Trainingsumfang von 15 ± 4 Stunden pro Woche teil. Das maximale isokinetische Drehmoment (PIT) der Rumpfflexoren (PITFlex), -extensoren (PITEx) und -rotatoren (PITRot) wurde unter Verwendung eines isokinetischen Dynamometers (IsoMed 2000) erfasst. Zusätzlich wurden kinetische Parameter (mechanische Arbeit [W], dynamisch-realisierte Maximalkraft [Fmax]) bei Anriss-Bewegung im Stand und bei Anriss- mit Eindrehbewegung (d. h. Morote-seoi-nage) mithilfe eines judospezifischen Mess- und Informationssystems (JERGo©) erhoben. Ergebnisse: Die statistische Analyse zeigte signifikante Korrelationen (0,62 ≤ r P ≤ 0,72) zwischen den maximalen isokinetischen Drehmomenten (PITFlex, PITEx, PITRot) und der Anriss-Bewegung im Stand (W). Zudem konnten signifikante Zusammenhänge (0,59 ≤ r P ≤ 0,65) zwischen den isokinetischen Tests (PITEx, PITRot) und Fmax auf der Hubarmseite bei der Anriss-Bewegung im Stand gefunden werden. Für die Anriss- mit Eindrehbewegung ergaben sich signifikante Korrelationen (0,47 ≤ r P ≤ 0,88) zwischen den isokinetischen Tests (PITFlex, PITEx, PITRot) und Leistungskennwerten der judospezifischen Bewegung (W und Fmax), unabhängig von der untersuchten Armseite. Es wurden vergleichbare Korrelationskoeffizienten zwischen PIT der Rumpfflexoren, -extensoren und -rotatoren und judospezifischen Leistungskennwerten festgestellt. Weiterhin identifizierte die Regressionsanalyse den Kennwert PIT bei Rumpfextension als besten Prädiktor für die mechanische Arbeit bei Anriss-Bewegung im Stand (46,9 %). Bei der Anriss- mit Eindrehbewegung konnte PIT der Rumpfrotatoren auf die Hubarmseite als bester Prädiktor für die mechanische Arbeit (69,4 %) ermittelt werden. Schlussfolgerung: Die Ergebnisse zeigen, dass die Rumpfkraft, insbesondere bei der Rumpfrotationsbewegung, mit Variablen der judospezifischen Leistungskennwerte bei der Anriss- mit Eindrehbewegung assoziiert ist. Dies impliziert, dass vor allem durch rumpfrotationskräftigende Übungen Einfluss auf die Anriss- mit Eindrehbewegung (d. h. Morote-seoi-nage) genommen werden könnte. KW - combat sport KW - athletic performance KW - Morote-seoi-nage KW - Kampfsport KW - sportliche Leistung Y1 - 2020 U6 - https://doi.org/10.1055/a-0677-9608 SN - 0932-0555 SN - 1439-1236 VL - 34 IS - 1 SP - 18 EP - 27 PB - Thieme CY - Stuttgart ER - TY - JOUR A1 - Kather, Fritz A1 - Hadzic, Miralem A1 - Hehle, Teresa A1 - Eichler, Sarah A1 - Klein, Julia A1 - Völler, Heinz A1 - Salzwedel, Annett T1 - Test-retest reliability of the Mini Nutritional Assessment- Short Form (MNA-SF) in older patients undergoing cardiac rehabilitation JF - Journal of geriatric cardiology KW - Cardiac rehabilitation KW - Malnutrition KW - Octogenarians KW - Test-retest KW - reliability Y1 - 2020 U6 - https://doi.org/10.11909/j.issn.1671-5411.2020.09.007 SN - 1671-5411 VL - 17 IS - 9 SP - 574 EP - 579 PB - English China Online Journals, ECOJ CY - Windsor [u.a.] ER - TY - JOUR A1 - Völler, Heinz A1 - Schwaab, Bernhard T1 - Kardiologische Rehabilitation JF - Der Kardiologe : die Fortbildungszeitschrift der Deutschen Gesellschaft für Kardiologie, Herz- und Kreislaufforschung N2 - Hintergrund Eine Verlängerung der Lebens- und Arbeitszeit erfordert einen aktiven Lebensstil, eine Optimierung von kardiovaskulären Risikofaktoren und psychosoziale Unterstützung chronisch Herzkranker. Fragestellung Können die Prognose und Lebensqualität sowie die soziale oder berufliche Teilhabe kardiovaskulär Erkrankter durch kardiologische Rehabilitation (KardReha) verbessert werden? Material und Methode Auf der Grundlage neuer Metaanalysen und aktueller Positionspapiere gibt die S3-Leitlinie zur kardiologischen Rehabilitation evidenzbasierte Empfehlungen. Ergebnisse Eine KardReha reduziert bei Patienten nach akutem Koronarsyndrom, nach PCI („percutaneous coronary interventions“) oder nach aortokoronarer Koronarbypassoperation (ACB-Op.) sowie nach Klappenkorrektur die Gesamtsterblichkeit. Bei Patienten mit systolischer Herzinsuffizienz (HFrEF [„heart failure with reduced ejection fraction“]) werden Belastbarkeit und Lebensqualität durch eine KardReha verbessert. Psychosozialer Distress kann verringert und die berufliche Wiedereingliederung besser strukturiert werden. Schlussfolgerung Im Jahr 2019 liegen aktuelle, evidenzbasierte Leitlinien vor, die aufgrund verbesserter Prognose, Belastbarkeit und Lebensqualität eine multimodale kardiologische Rehabilitation bei Patienten nach akutem kardialem Ereignis auch bei technischem Fortschritt (z. B. katheterbasierter Klappenkorrektur) und unter Aspekten der sozialen und beruflichen Teilhabe empfehlen. N2 - Background Prolonging the life span and working life requires an active lifestyle, optimization of cardiovascular risk factors and psychosocial support for patients suffering from chronic heart disease. Objective Is it possible to improve the prognosis and quality of life as well as social and occupational participation of patients with cardiovascular diseases by cardiac rehabilitation? Material and methods The S3 guidelines on cardiac rehabilitation in German-speaking countries provide evidence-based recommendations based on recent meta-analyses and current position papers. Results Cardiac rehabilitation is able to reduce overall mortality in patients with acute coronary syndrome, after percutaneous coronary interventions or surgical revascularization as well as after heart valve correction. In patients with systolic heart failure (heart failure with reduced ejection fraction, HFrEF) exercise capacity and quality of life are improved by cardiac rehabilitation. Psychosocial distress can be reduced and occupational reintegration can be adequately planned. Conclusion In 2019 current evidence-based guidelines are available that recommend a multimodal cardiac rehabilitation in patients after an acute cardiac event, due to improvement of prognosis, exercise capacity and quality of life as well as due to technical progress (e.g. catheter-based valve correction) and with respect to social and professional participation. T2 - Cardiac rehabilitation KW - Koronare Herzerkrankung KW - Herzinsuffizienz KW - Herzklappenkorrektur KW - Psychosozialer Distress KW - Lebensqualität KW - Coronary artery disease KW - Heart failure KW - Heart valve correction KW - Psychosocial distress KW - Quality of life Y1 - 2020 U6 - https://doi.org/10.1007/s12181-020-00384-2 SN - 1864-9718 SN - 1864-9726 VL - 14 IS - 2 SP - 106 EP - 112 PB - Springer CY - Berlin ER - TY - JOUR A1 - Brand, Ralf A1 - Voelcker-Rehage, Claudia T1 - DEAL und eine Zwischenbilanz über die Entwicklung der Zeitschrift T1 - DEAL and an interim report on the journal’s development JF - German journal of exercise and sport research JF - Sportwissenschaft Y1 - 2020 U6 - https://doi.org/10.1007/s12662-020-00645-y SN - 2509-3142 SN - 2509-3150 VL - 50 IS - 1 SP - 1 EP - 4 PB - Springer CY - New York ER - TY - JOUR A1 - Rebitschek, Felix G. A1 - Gigerenzer, Gerd T1 - Assessing the quality of digital health services T1 - Einschätzung der Qualität digitaler Gesundheitsangebote BT - how can informed decisions be promoted? BT - wie können informierte Entscheidungen gefördert werden? JF - Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz N2 - Eine wichtige Voraussetzung für das Gelingen der Digitalisierung des Gesundheitswesens ist die digitale Risikokompetenz der Nutzer, also ihre Fähigkeit, Nutzen und Schaden von digitalen Technologien und Informationen zu beurteilen, digitale Angebote kritisch zu nutzen und sich auch mit statistischer Evidenz auseinanderzusetzen. Wie finden Menschen qualitätsgesicherte Gesundheitsinformationen und wie können sie die Qualität von algorithmischen Entscheidungssystemen besser beurteilen? In diesem narrativen Beitrag sollen zwei Ansätze aufgezeigt werden, wie die Fähigkeit zum informierten Entscheiden gefördert werden kann. Evidenzbasierte und verlässliche Gesundheitsinformationen existieren im Internet, müssen aber von einer Vielzahl unzuverlässiger Informationen unterschieden werden. Verschiedene Institutionen im deutschen Sprachraum haben deshalb Anleitungen bereitgestellt, um Laien eine informierte Entscheidung zu erleichtern. Beispielsweise hat das Harding-Zentrum für Risikokompetenz in Potsdam für diese Zwecke einen Entscheidungsbaum („fast-and-frugal tree“) entwickelt. Im Umgang mit Algorithmen können natürliche Häufigkeitsbäume (NFTs) helfen, die Güte und Fairness eines algorithmischen Entscheidungssystems zu beurteilen. Neben zuverlässigen und verständlichen digitalen Angeboten sollten weitere Werkzeuge für Laien zur Beurteilung von Informationen und Algorithmen entwickelt und bereitgestellt werden. Diese können auch in Schulungsprogramme zur digitalen Kompetenzförderung aufgenommen werden. Damit wäre ein wichtiger Schritt zum Gelingen der Digitalisierung in der Prävention und Gesundheitsförderung getan. N2 - An important prerequisite for the success of the digitisation of the healthcare system are risk-literate users. Risk literacy means the ability to weigh potential benefits and harms of digital technologies and information, to use digital services critically, and to understand statistical evidence. How do people find reliable and comprehensible health information on the Internet? How can they better assess the quality of algorithmic decision systems? This narrative contribution describes two approaches that show how the competence to make informed decisions can be promoted. Evidence-based and reliable health information exists on the Internet but must be distinguished from a large amount of unreliable information. Various institutions in the German-speaking world have therefore provided guidance to help laypersons make informed decisions. The Harding Center for Risk Literacy in Potsdam, for example, has developed a decision tree ("fast-and-frugal tree"). When dealing with algorithms, natural frequency trees (NFTs) can help to assess the quality and fairness of an algorithmic decision system. Independent of reliable and comprehensible digital health services, further tools for laypersons to assess information and algorithms should be developed and provided. These tools can also be included in institutional training programmes for the promotion of digital literacy. This would be an important step towards the success of digitisation in prevention and health promotion. KW - risk literacy KW - informed decision-making KW - digital health information KW - algorithmic decision systems KW - algorithm performance KW - Risikokompetenz KW - Informiertes Entscheiden KW - Digitale Gesundheitsinformationen KW - Algorithmische Entscheidungssysteme KW - Algorithmengüte Y1 - 2020 U6 - https://doi.org/10.1007/s00103-020-03146-3 SN - 1436-9990 SN - 1437-1588 VL - 63 IS - 6 SP - 665 EP - 673 PB - Springer CY - New York ER - TY - JOUR A1 - Baritello, Omar A1 - Khajooei, Mina A1 - Engel, Tilman A1 - Kopinski, Stephan A1 - Quarmby, Andrew James A1 - Müller, Steffen A1 - Mayer, Frank T1 - Neuromuscular shoulder activity during exercises with different combinations of stable and unstable weight mass JF - BMC sports science, medicine and rehabilitation N2 - Background Recent shoulder injury prevention programs have utilized resistance exercises combined with different forms of instability, with the goal of eliciting functional adaptations and thereby reducing the risk of injury. However, it is still unknown how an unstable weight mass (UWM) affects the muscular activity of the shoulder stabilizers. Aim of the study was to assess neuromuscular activity of dynamic shoulder stabilizers under four conditions of stable and UWM during three shoulder exercises. It was hypothesized that a combined condition of weight with UWM would elicit greater activation due to the increased stabilization demand. Methods Sixteen participants (7 m/9 f) were included in this cross-sectional study and prepared with an EMG-setup for the: Mm. upper/lower trapezius (U.TA/L.TA), lateral deltoid (DE), latissimus dorsi (LD), serratus anterior (SA) and pectoralis major (PE). A maximal voluntary isometric contraction test (MVIC; 5 s.) was performed on an isokinetic dynamometer. Next, internal/external rotation (In/Ex), abduction/adduction (Ab/Ad) and diagonal flexion/extension (F/E) exercises (5 reps.) were performed with four custom-made-pipes representing different exercise conditions. First, the empty-pipe (P; 0.5 kg) and then, randomly ordered, water-filled-pipe (PW; 1 kg), weight-pipe (PG; 4.5 kg) and weight + water-filled-pipe (PWG; 4.5 kg), while EMG was recorded. Raw root-mean-square values (RMS) were normalized to MVIC (%MVIC). Differences between conditions for RMS%MVIC, scapular stabilizer (SR: U.TA/L.TA; U.TA/SA) and contraction (CR: concentric/eccentric) ratios were analyzed (paired t-test; p <= 0.05; Bonferroni adjusted alpha = 0.008). Results PWG showed significantly greater muscle activity for all exercises and all muscles except for PE compared to P and PW. Condition PG elicited muscular activity comparable to PWG (p > 0.008) with significantly lower activation of L.TA and SA in the In/Ex rotation. The SR ratio was significantly higher in PWG compared to P and PW. No significant differences were found for the CR ratio in all exercises and for all muscles. Conclusion Higher weight generated greater muscle activation whereas an UWM raised the neuromuscular activity, increasing the stabilization demands. Especially in the In/Ex rotation, an UWM increased the RMS%MVIC and SR ratio. This might improve training effects in shoulder prevention and rehabilitation programs. KW - EMG KW - instability KW - overhead athlete KW - unstable resistance training KW - water KW - pipe KW - rotator cuff Y1 - 2020 U6 - https://doi.org/10.1186/s13102-020-00168-x SN - 2052-1847 VL - 12 IS - 1 PB - BioMed Central CY - London ER - TY - JOUR A1 - Sandau, Ingo A1 - Granacher, Urs T1 - Effects of the barbell load on the acceleration phase during the snatch in elite Olympic weightlifting JF - Sports N2 - The load-depended loss of vertical barbell velocity at the end of the acceleration phase limits the maximum weight that can be lifted. Thus, the purpose of this study was to analyze how increased barbell loads affect the vertical barbell velocity in the sub-phases of the acceleration phase during the snatch. It was hypothesized that the load-dependent velocity loss at the end of the acceleration phase is primarily associated with a velocity loss during the 1st pull. For this purpose, 14 male elite weightlifters lifted seven load-stages from 70-100% of their personal best in the snatch. The load-velocity relationship was calculated using linear regression analysis to determine the velocity loss at 1st pull, transition, and 2nd pull. A group mean data contrast analysis revealed the highest load-dependent velocity loss for the 1st pull (t = 1.85, p = 0.044, g = 0.49 [-0.05, 1.04]) which confirmed our study hypothesis. In contrast to the group mean data, the individual athlete showed a unique response to increased loads during the acceleration sub-phases of the snatch. With the proposed method, individualized training recommendations on exercise selection and loading schemes can be derived to specifically improve the sub-phases of the snatch acceleration phase. Furthermore, the results highlight the importance of single-subject assessment when working with elite athletes in Olympic weightlifting. KW - biomechanics KW - barbell velocity KW - performance KW - training KW - load-velocity KW - relationship Y1 - 2020 U6 - https://doi.org/10.3390/sports8050059 SN - 2075-4663 VL - 8 IS - 5 PB - MDPI CY - Basel ER - TY - JOUR A1 - Jafarnezhadgero, Amir Ali A1 - Anvari, Maryam A1 - Granacher, Urs T1 - Long-term effects of shoe mileage on ground reaction forces and lower limb muscle activities during walking in individuals with genu varus JF - Clinical biomechanics N2 - Background: Shoe mileage is an important factor that may influence the risk of sustaining injuries during walking. The aims of this study were to examine the effects of shoe mileage on ground reaction forces and activity of lower limb muscles during walking in genu varus individuals compared with controls. Methods: Fifteen healthy and 15 genu varus females received a new pair of running shoes. They were asked to wear these shoes over 6 months. Pre and post intervention, mechanical shoe testing was conducted and ground reaction forces and muscle activities of the right leg were recorded during walking at preferred gait speed. Findings: Significant group-by-time interactions were found for shoe stiffness, antero-posterior and vertical impact peak. We observed higher shoe stiffness and lower impact peaks after intervention in both groups with larger effect sizes in genu varus. Significant group-by-time interactions were identified for vastus medialis (loading phase) and rectus femoris (loading and push-off). For vastus medialis, significant decreases were found from pre-to-post during the loading phase in the control group. Rectus femoris activity was higher post intervention during the loading and push-off phases in both groups with larger effect sizes in genu varus. Interpretation: Our findings indicate that the observed changes in ground reaction forces are more prominent in genu varus individuals. Together with our findings on shoe stiffness, it seems appropriate to change running shoes after an intense wearing time of 6 months, particularly in genu varus individuals. KW - footwear KW - electromyography KW - loading rate KW - patients Y1 - 2020 U6 - https://doi.org/10.1016/j.clinbiomech.2020.01.006 SN - 0268-0033 SN - 1879-1271 VL - 73 SP - 55 EP - 62 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Kangas, Maria A1 - Heissel, Andreas T1 - Mental health literacy, treatment preferences and the lived experience of mental health problems in an Australian cancer sample JF - Psycho-oncology N2 - Objectives: The prevalence rates for mental health (MH) problems in cancer patients is high, although reduced uptake of services may be influenced by mental health literacy (MHL). The objective of this study was to investigate the MHL for depression and panic disorder (PD), including treatment preferences in Australian adults who had been diagnosed and treated for cancer, and whether MHL and treatment preferences was influenced by sex, age, and individuals' lived MH experience. Method: A total of 421 cancer survivors (n = 378 females) completed a self-report survey. Participants were asked to specify whether they had a lived experience with anxiety and/or depression, and to indicate treatment preferences for managing cancer-related distress. Two vignettes were administered to assess MHL for depression and PD. Results: The MHL accuracy for depression was higher than PD. Accuracy rates were higher for females with a lived experience with anxiety and/or depression; although the accuracy rate for PD was significantly lower in males. A high proportion of individuals preferred exercise and in-person counselling to manage depression and PD. Internet-based therapies were not strongly preferred for managing MH problems. Conclusions: The MHL for depression and PD is moderate for adult cancer survivors, with higher levels indicated for individuals with a personal lived experience with anxiety and/or depression. Public health campaigns for enhancing MHL should broaden to include individuals experiencing comorbid physical health conditions. Health providers also need to take into account client preferences for evidence-based therapies. KW - anxiety KW - cancer KW - exercise KW - major depression KW - mental health KW - preferences KW - psycho-oncology KW - treatment Y1 - 2020 U6 - https://doi.org/10.1002/pon.5520 SN - 1057-9249 SN - 1099-1611 VL - 29 IS - 11 SP - 1883 EP - 1894 PB - Wiley CY - New York, NY ER - TY - JOUR A1 - Börnert-Ringleb, Moritz A1 - Westphal, Andrea A1 - Zaruba, Nicole A1 - Gutmann, Franziska A1 - Vock, Miriam T1 - The relationship between attitudes toward inclusion, beliefs about teaching and learning, and subsequent automatic evaluations amongst student teachers JF - Frontiers in education N2 - Teachers' attitudes toward inclusion are frequently cited as being an important predictor of how successfully a given inclusive school system is implemented. At the same time, beliefs about the nature of teaching and learning are discussed as a possible predictor of attitudes toward inclusion. However, more recent research emphasizes the need of considering implicit processes, such as automatic evaluations, when describing attitudes and beliefs. Previous evidence on the association of attitudes toward inclusion and beliefs about teaching and learning is solely based on explicit reports. Therefore, this study aims to examine the relationship between attitudes toward inclusion, beliefs about teaching and learning, and the subsequent automatic evaluations of pre-service teachers (N = 197). The results revealed differences between pre-service teachers' explicit attitudes/beliefs and their subsequent automatic evaluations. Differences in the relationship between attitudes toward inclusion and beliefs about teaching and learning occur when teachers focus either on explicit measures or automatic evaluations. These differences might be due to different facets of the same attitude object being represented. Relying solely on either explicit measures or automatic evaluations at the exclusion of the other might lead to erroneous assumptions about the relation of attitudes toward inclusion and beliefs about teaching and learning. KW - inclusion KW - attitudes KW - teaching KW - automatic evaluation KW - beliefs KW - implicit Y1 - 2020 U6 - https://doi.org/10.3389/feduc.2020.584464 SN - 2504-284X VL - 5 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Rowley, K. Michael A1 - Engel, Tilman A1 - Kulig, Kornelia T1 - Trunk and hip muscle activity during the Balance-Dexterity task in persons with and without recurrent low back pain JF - Journal of electromyography and kinesiology N2 - Coordination of the trunk and hips is crucial for successful dynamic balance in many activities of daily living. Persons with recurrent low back pain (rLBP), both while symptomatic and during periods of symptom remission, exhibit dysfunctional muscle activation patterns and coordination of these joints. In a novel dynamic balance task where persons in remission from rLBP exhibit dissociated trunk motion, it is unknown how trunk and hip musculature are coordinated. Activation of hip and trunk muscles were acquired from nineteen persons with and without rLBP during the Balance-Dexterity Task, which involves balancing on one limb while compressing an unstable spring with the other. There were no between-group differences in activation amplitude for any muscle groups tested. In back-healthy control participants, hip and trunk muscle activation amplitudes increased proportionally in response to the added instability of the spring (R = 0.837, p < 0.001). Increases in muscle activation amplitudes in the group in remission from rLBP were not proportional (R = 0.113, p = 0.655). Instead, hip muscle activation in this group was associated with task performance, i.e. dexterous control of the spring (R = 0.676, p = 0.002). These findings highlight atypical coordination of hip and trunk musculature potentially related to task demands in persons with rLBP even during remission from pain. KW - balance KW - low back pain KW - trunk and hip coordination KW - lumbopelvic Y1 - 2020 U6 - https://doi.org/10.1016/j.jelekin.2019.102378 SN - 1050-6411 SN - 1873-5711 VL - 50 PB - Elsevier Science CY - Amsterdam ER - TY - JOUR A1 - Heissel, Andreas A1 - Pietrek, Anou F. A1 - Schwefel, Melanie A1 - Abula, Kahar A1 - Wilbertz, Gregor A1 - Heinzel, Stephan A1 - Rapp, Michael A. T1 - STEP.De study BT - a multicentre cluster-randomised effectiveness trial of exercise therapy for patients with depressive symptoms in healthcare services : study protocol JF - BMJ open N2 - Introduction Although exercise therapy has widely been shown to be an efficacious treatment modality for depression, evidence for its effectiveness and cost efficiency is lacking. The Sport/Exercise Therapy for Depression study is a multicentre cluster-randomised effectiveness trial that aims to compare the effectiveness and cost efficiency of exercise therapy and psychotherapy as antidepressant treatment.
Methods and analysis 480 patients (aged 18-65) with an International Classification of Diseases diagnosis associated with depressive symptoms are recruited. Up to 30 clusters (psychotherapists) are randomly assigned to allocate patients to either an exercise or a psychotherapy treatment as usual in a 2: 1 ratio. The primary outcome (depressive symptoms) and the secondary outcomes (work and social adjustment, quality of life) will be assessed at six measurement time points (t0: baseline, t1: 8 weeks after treatment initiation, t2: 16 weeks after treatment initiation, t3/ 4/5: 2, 6, 12 months after treatment). Linear regression analyses will be used for the primary endpoint data analysis. For the secondary endpoints, mixed linear and logistic regression models with fixed and random factors will be added. For the cost efficiency analysis, expenditures in the 12 months before and after the intervention and the outcome difference will be compared between groups in a multilevel model. Recruitment start date was 1 July 2018 and the planned recruitment end date is 31 December 2020.
Ethics and dissemination The study protocol was approved by the ethics committee of the University of Potsdam (No. 17/2018) and the Freie Universitat Berlin (No. 206/2018) and registered in the ISRCTN registry. Informed written consent will be obtained from all participants. The study will be reported in accordance with the Consolidated Standards of Reporting Trials and the Recommendations for Interventional Trials statements. The results will be published in peer-reviewed academic journals and disseminated to the public. Y1 - 2020 U6 - https://doi.org/10.1136/bmjopen-2019-036287 SN - 2044-6055 VL - 10 IS - 4 PB - BMJ Publishing Group CY - London ER - TY - JOUR A1 - Hortobagyi, Tibor A1 - Granacher, Urs A1 - Fernandez-del-Olmo, Miguel A1 - Howatson, Glyn A1 - Manca, Andrea A1 - Deriu, Franca A1 - Taube, Wolfgang A1 - Gruber, Markus A1 - Marquez, Gonzalo A1 - Lundbye-Jensen, Jesper A1 - Colomer-Poveda, David T1 - Functional relevance of resistance training-induced neuroplasticity in health and disease JF - Neuroscience & biobehavioral reviews : official journal of the International Behavioral Neuroscience Society N2 - Repetitive, monotonic, and effortful voluntary muscle contractions performed for just a few weeks, i.e., resistance training, can substantially increase maximal voluntary force in the practiced task and can also increase gross motor performance. The increase in motor performance is often accompanied by neuroplastic adaptations in the central nervous system. While historical data assigned functional relevance to such adaptations induced by resistance training, this claim has not yet been systematically and critically examined in the context of motor performance across the lifespan in health and disease. A review of muscle activation, brain and peripheral nerve stimulation, and imaging data revealed that increases in motor performance and neuroplasticity tend to be uncoupled, making a mechanistic link between neuroplasticity and motor performance inconclusive. We recommend new approaches, including causal mediation analytical and hypothesis-driven models to substantiate the functional relevance of resistance training-induced neuroplasticity in the improvements of gross motor function across the lifespan in health and disease. KW - Maximal voluntary contraction (MVC) KW - strength training KW - Electromyography (EMG) KW - Transcranial magnetic brain stimulation (TMS) KW - Electroencephalography (EEG) KW - Functional magnetic resonance imaging (fMRI) KW - athletic performance KW - aging KW - Parkinson's disease KW - Multiple sclerosis KW - stroke KW - directed acyclic graphs KW - causal mediation analysis Y1 - 2020 U6 - https://doi.org/10.1016/j.neubiorev.2020.12.019 SN - 0149-7634 SN - 1873-7528 VL - 122 SP - 79 EP - 91 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Salzwedel, Annett A1 - Jensen, Katrin A1 - Rauch, Bernhard A1 - Doherty, Patrick A1 - Metzendorf, Maria-Inti A1 - Hackbusch, Matthes A1 - Völler, Heinz A1 - Schmid, Jean-Paul A1 - Davos, Constantinos H. T1 - Effectiveness of comprehensive cardiac rehabilitation in coronary artery disease patients treated according to contemporary evidence based medicine BT - update of the Cardiac Rehabilitation Outcome Study (CROS-II) JF - European journal of preventive cardiology : the official ESC journal for primary & secondary cardiovascular prevention, rehabilitation and sports cardiology N2 - Background Despite numerous studies and meta-analyses the prognostic effect of cardiac rehabilitation is still under debate. This update of the Cardiac Rehabilitation Outcome Study (CROS II) provides a contemporary and practice focused approach including only cardiac rehabilitation interventions based on published standards and core components to evaluate cardiac rehabilitation delivery and effectiveness in improving patient prognosis. Design A systematic review and meta-analysis. Methods Randomised controlled trials and retrospective and prospective controlled cohort studies evaluating patients after acute coronary syndrome, coronary artery bypass grafting or mixed populations with coronary artery disease published until September 2018 were included. Resulte Based on CROS inclusion criteria out of 7096 abstracts six additional studies including 8671 patients were identified (two randomised controlled trials, two retrospective controlled cohort studies, two prospective controlled cohort studies). In total, 31 studies including 228,337 patients were available for this meta-analysis (three randomised controlled trials, nine prospective controlled cohort studies, 19 retrospective controlled cohort studies; 50,653 patients after acute coronary syndrome 14,583, after coronary artery bypass grafting 163,101, mixed coronary artery disease populations; follow-up periods ranging from 9 months to 14 years). Heterogeneity in design, cardiac rehabilitation delivery, biometrical assessment and potential confounders was considerable. Controlled cohort studies showed a significantly reduced total mortality (primary endpoint) after cardiac rehabilitation participation in patients after acute coronary syndrome (prospective controlled cohort studies: hazard ratio (HR) 0.37, 95% confidence interval (CI) 0.20-0.69; retrospective controlled cohort studies HR 0.64, 95% CI 0.53-0.76; prospective controlled cohort studies odds ratio 0.20, 95% CI 0.08-0.48), but the single randomised controlled trial fulfilling the CROS inclusion criteria showed neutral results. Cardiac rehabilitation participation was also associated with reduced total mortality in patients after coronary artery bypass grafting (retrospective controlled cohort studies HR 0.62, 95% CI 0.54-0.70, one single randomised controlled trial without fatal events), and in mixed coronary artery disease populations (retrospective controlled cohort studies HR 0.52, 95% CI 0.36-0.77; two out of 10 controlled cohort studies with neutral results). Conclusion CROS II confirms the effectiveness of cardiac rehabilitation participation after acute coronary syndrome and after coronary artery bypass grafting in actual clinical practice by reducing total mortality under the conditions of current evidence-based coronary artery disease treatment. The data of CROS II, however, underscore the urgent need to define internationally accepted minimal standards for cardiac rehabilitation delivery as well as for scientific evaluation. KW - cardiac rehabilitation KW - cardiac rehabilitation delivery KW - acute coronary KW - syndrome KW - coronary bypass grafting KW - coronary artery disease KW - mortality Y1 - 2020 U6 - https://doi.org/10.1177/2047487320905719 SN - 2047-4873 SN - 2047-4881 VL - 27 IS - 16 SP - 1756 EP - 1774 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - McDowell, Michelle A1 - Pachur, Thorsten T1 - Availability, affect, and decisions to seek information about cancer risks JF - Medical decision making : MDM N2 - How do people decide which risks they want to get informed about? The present study examines the role of the availability and affect heuristics on these decisions. Participants (N= 100, aged 19-72 years) selected for which of 23 cancers they would like to receive an information brochure, reported the number of occurrences of each type of cancer in their social circle (availability), and rated their dread reaction to each type of cancer (affect); they also made relative judgments about which of 2 cancers was more common in Germany (judged risk). Participants tended to choose information brochures for those cancers for which they indicated a higher availability within their social networks as well as for cancers they dreaded. Mediation analyses suggested that the influence of availability and affect on information choice was only partly mediated by judged risk. The results demonstrate the operation of 2 key judgment heuristics (availability and affect), previously studied in risk perception, also in decisions about information choice. We discuss how our findings can be used to identify which risks are likely to fall from people's radar. KW - information seeking KW - risk perception Y1 - 2020 U6 - https://doi.org/10.1177/0272989X20951775 SN - 0272-989X SN - 1552-681X VL - 40 IS - 8 SP - 941 EP - 945 PB - Sage Publ. CY - Thousand Oaks ER - TY - JOUR A1 - Grahn, Patricia A1 - Bonaventura, Klaus A1 - Wippert, Pia-Maria T1 - Stress levels in cardiac catherization laboratory BT - can an MBSR intervention reduce stress of medical practitioners in a cardiac catherization laboratory? JF - Psychoneuroendocrinology Y1 - 2020 U6 - https://doi.org/10.1016/j.psyneuen.2020.104925 SN - 0306-4530 SN - 1873-3360 VL - 119 SP - S3 EP - S3 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Thier, Anne A1 - Holmberg, Christine T1 - The patients’ view BT - age-related macular degeneration and its effects : a meta-synthesis JF - Disability and rehabilitation : an international, multidisciplinary journal N2 - Aim:The aim of this meta-synthesis is to find out what it means for patients with age-related macular degeneration to live with visual impairment, how they cope with the illness and how they experience their medical care, including vascular endothelial growth factor inhibitor therapy. Method:Inclusion criteria: qualitative studies exploring patients' experiences with age-related macular degeneration in their daily lives and with medical care, published in journals in English or German. The included studies were analysed following the rules and principles of grounded theory. Results:For the analysis, twenty-four articles matching the inclusion criteria were identified. Three main analytic themes emerged from the included studies: (i) a life shaped by losses; (ii) the burden of medical treatment; and (iii) coping with vision loss. For patients, visual impairment/vision loss means living with multiple losses in various domains of life. With the introduction of vascular endothelial growth factor inhibitor therapy, patients with neovascular age-related macular degeneration have a good chance of slowing down the disease progression; therapy does, however, also represent a major burden. Conclusion:New strategies need to be conceived to reduce the burden of medical treatment and to improve the dissemination of information about age-related macular degeneration. KW - Age-related macular degeneration KW - visual impairment KW - vascular KW - endothelial growth factor inhibitor therapy KW - patients' experiences KW - meta-synthesis KW - qualitative research Y1 - 2020 U6 - https://doi.org/10.1080/09638288.2020.1775901 SN - 0963-8288 SN - 1464-5165 VL - 44 IS - 5 SP - 661 EP - 671 PB - Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Wochatz, Monique A1 - Engel, Tilman A1 - Müller, Steffen A1 - Mayer, Frank T1 - Alterations in scapular kinematics and scapular muscle activity after fatiguing shoulder flexion and extension movements JF - Medicine and science in sports and exercise : MSSE N2 - Repetitive overhead motions in combination with heavy loading were identified as risk factors for the development of shoulder pain. However, the underlying mechanism is not fully understood. Altered scapular kinematics as a result of muscle fatigue is suspected to be a contributor. PURPOSE: To determine scapular kinematics and scapular muscle activity at the beginning and end of constant shoulder flexion and extension loading in asymptomatic individuals. METHODS: Eleven asymptomatic adults (28±4yrs; 1.74±0.13m; 74±16kg) underwent maximum isokinetic loading of shoulder flexion (FLX) and extension (EXT) in the sagittal plane (ROM: 20- 180°; concentric mode; 180°/s) until individual peak torque was reduced by 50%. Simultaneously 3D scapular kinematics were assessed with a motion capture system and scapular muscle activity with a 3-lead sEMG of upper and lower trapezius (UT, LT) and serratus anterior (SA). Scapular position angles were calculated for every 20° increment between 20-120° humerothoracic positions. Muscle activity was quantified by amplitudes (RMS) of the total ROM. Descriptive analyses (mean±SD) of kinematics and muscle activity at begin (taskB) and end (taskE) of the loading task was followed by ANOVA and paired t-tests. RESULTS: At taskB activity ranged from 589±343mV to 605±250mV during FLX and from 105±41mV to 164±73mV during EXT across muscles. At taskE activity ranged from 594±304mV to 875±276mV during FLX and from 97±33mV to 147±57mV during EXT. Differences with increased muscle activity were seen for LT and UT during FLX (meandiff= 141±113mV for LT, p<0.01; 191±153mV for UT, p<0.01). Scapula position angles continuously increased in upward rotation, posterior tilt and external rotation during FLX and reversed during EXT both at taskB and taskE. At taskE scapula showed greater external rotation (meandiff= 3.6±3.7°, p<0.05) during FLX and decreased upward rotation (meandiff= 1.9±2.3°, p<0.05) and posterior tilt (meandiff= 1.0±2.1°, p<0.05) during EXT across humeral positions. CONCLUSIONS: Force reduction in consequence of fatiguing shoulder loading results in increased scapular muscle activity and minor alterations in scapula motion. Whether even small changes have a clinical impact by creating unfavorable subacromial conditions potentially initiating pain remains unclear. Y1 - 2020 U6 - https://doi.org/10.1249/01.mss.0000676540.02017.2c SN - 0195-9131 SN - 1530-0315 VL - 52 IS - 17 SP - 274 EP - 274 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Thiele, Dirk A1 - Prieske, Olaf A1 - Chaabene, Helmi A1 - Granacher, Urs T1 - Effects of strength training on physical fitness and sport-specific performance in recreational, sub-elite, and elite rowers BT - a systematic review with meta-analysis JF - Journal of sports sciences N2 - The purpose of this systematic review with meta-analysis was to examine the effects of strength training (ST) on selected components of physical fitness (e.g., lower/upper limb maximal strength, muscular endurance, jump performance, cardiorespiratory endurance) and sport-specific performance in rowers. Only studies with an active control group were included if they examined the effects of ST on at least one proxy of physical fitness and/or sport-specific performance in rowers. Weighted and averaged standardized mean differences (SMD) were calculated using random-effects models. Subgroup analyses were computed to identify effects of ST type or expertise level on sport-specific performance. Our analyses revealed significant small effects of ST on lower limb maximal strength (SMD = 0.42, p = 0.05) and on sport-specific performance (SMD = 0.32, p = 0.05). Non-significant effects were found for upper limb maximal strength, upper/lower limb muscular endurance, jump performance, and cardiorespiratory endurance. Subgroup analyses for ST type and expertise level showed non-significant differences between the respective subgroups of rowers (p >= 0.32). Our systematic review with meta-analysis indicated that ST is an effective means for improving lower limb maximal strength and sport-specific performance in rowers. However, ST-induced effects are neither modulated by ST type nor rowers' expertise level. KW - resistance training KW - plyometric training KW - on-water performance KW - race KW - time KW - oarsmen KW - athletic performance Y1 - 2020 U6 - https://doi.org/10.1080/02640414.2020.1745502 SN - 0264-0414 SN - 1466-447X VL - 38 IS - 10 SP - 1186 EP - 1195 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Henschke, Jakob A1 - Stoll, Josefine A1 - Kopinski, Stephan A1 - Lu, Yu-Hsien A1 - Mayer, Frank T1 - The effect of a low volume trunk-stabilisation exercise protocol on biomechanical function and compliance JF - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2020 U6 - https://doi.org/10.1249/01.mss.0000678760.27551.f6 SN - 0195-9131 SN - 1530-0315 VL - 52 IS - 17 SP - 446 EP - 447 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Völler, Heinz A1 - Heyne, Karen T1 - Evaluation of the Accuracy of the LumiraDx INR Test Using Patients in Receipt of Phenprocoumon Anticoagulation Therapy JF - Point of care : the journal of near-patient testing & technology N2 - Background: The LumiraDx INR Test is a new point-of-care diagnostic test designed to analyze fingerstick blood samples. The test was assessed in patients receiving phenprocoumon (NCT04074980). Methods: Venous plasma international normalized ratio (INR) was measured using the LumiraDx INR Test. LumiraDx INR Test-ascertained capillary whole blood INR was compared with venous plasma INR measured using the IL ACL Elite Pro and Sysmex CS-5100 reference instruments. Results: A total of 102 patients receiving phenprocoumon were recruited. The INR results from venous plasma and capillary whole blood that were analyzed on the LumiraDx INR Test correlated well with those measured using the IL ACL Elite Pro (plasma: n = 25, r = 0.981; capillary blood: n = 74, r = 0.949) and the Sysmex CS-5100 (n = 73, r = 0.950). Conclusions: The LumiraDx INR Test showed high accuracy in analyzing venous plasma and capillary whole blood from patients receiving phenprocoumon. KW - international normalized ratio KW - LumiraDx Platform KW - LumiraDx INR Test KW - oral anticoagulation KW - point-of-care KW - vitamin K antagonist therapy KW - phenprocoumon Y1 - 2020 U6 - https://doi.org/10.1097/POC.0000000000000207 SN - 1533-029X SN - 1533-0303 VL - 19 IS - 3 SP - 72 EP - 76 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Lesinski, Melanie A1 - Herz, Michael A1 - Schmelcher, Alina A1 - Granacher, Urs T1 - Effects of resistance training on physical fitness in healthy children and adolescents BT - an umbrella review JF - Sports medicine N2 - Background Over the past decades, an exponential growth has occurred with regards to the number of scientific publications including meta-analyses on youth resistance training (RT). Accordingly, it is timely to summarize findings from meta-analyses in the form of an umbrella review. Objectives To systematically review and summarise the findings of published meta-analyses that investigated the effects of RT on physical fitness in children and adolescents. Design Systematic umbrella review of meta-analyses. Data Sources Meta-analyses were identified using systematic literature searches in the databases PubMed, Web of Science, and Cochrane Library. Eligibility Criteria for Selecting Meta-analyses Meta-analyses that examined the effects of RT on physical fitness (e.g., muscle strength, muscle power) in healthy youth (<= 18 years). Results Fourteen meta-analyses were included in this umbrella review. Eleven of these meta-analyses reported between-subject effect sizes which are important to eliminate bias due to growth and maturation. RT produced medium-to-large effects on muscle strength, small-to-large effects on muscle power, small-to-medium effects on linear sprint, a medium effect on agility/change-of-direction speed, small-to-large effects on throwing performance, and a medium effect on sport-specific enhancement. There were few consistent moderating effects of maturation, age, sex, expertise level, or RT type on muscle strength and muscle power across the included meta-analyses. The analysed meta-analyses showed low-to-moderate methodological quality (AMSTAR2) as well as presented evidence of low-to-very low quality (GRADE). Conclusion This umbrella review proved the effectiveness of RT in youth on a high evidence level. The magnitude of effects varies according to the respective outcome measure and it appears to follow the principle of training specificity. Larger effect sizes were found for strength-related outcome measures. Future studies should consistently report data on participants' maturational status. More research is needed with prepubertal children and girls, irrespective of their maturational status. Y1 - 2020 U6 - https://doi.org/10.1007/s40279-020-01327-3 SN - 0112-1642 SN - 1179-2035 VL - 50 IS - 11 SP - 1901 EP - 1928 PB - Springer CY - Northcote ER - TY - JOUR A1 - Fühner, Thea Heidi A1 - Kliegl, Reinhold A1 - Arntz, Fabian A1 - Kriemler, Susi A1 - Granacher, Urs T1 - An update on secular trends in physical fitness of children and adolescents from 1972 to 2015 BT - a systematic review JF - Sports medicine N2 - Background There is evidence that physical fitness of children and adolescents (particularly cardiorespiratory endurance) has declined globally over the past decades. Ever since the first reports on negative trends in physical fitness, efforts have been undertaken by for instance the World Health Organization (WHO) to promote physical activity and fitness in children and adolescents. Therefore, it is timely to re-analyze the literature to examine whether previous reports on secular declines in physical fitness are still detectable or whether they need to be updated. Objectives The objective of this systematic review is to provide an 'update' on secular trends in selected components of physical fitness (i.e., cardiorespiratory endurance, relative muscle strength, proxies of muscle power, speed) in children and adolescents aged 6-18 years. Data Sources A systematic computerized literature search was conducted in the electronic databases PubMed and Web of Science to locate studies that explicitly reported secular trends in physical fitness of children and adolescents. Study Eligibility Criteria Studies were included in this systematic review if they examined secular trends between at least two time points across a minimum of 5 years. In addition, they had to document secular trends in any measure of cardiorespiratory endurance, relative muscle strength, proxies of muscle power or speed in apparently healthy children and adolescents aged 6-18 years. Study Appraisal and Synthesis Methods The included studies were coded for the following criteria: nation, physical fitness component (cardiorespiratory endurance, relative muscle strength, proxies of muscle power, speed), chronological age, sex (boys vs. girls), and year of assessment. Scores were standardized (i.e., converted to z scores) with sample-weighted means and standard deviations, pooled across sex and year of assessment within cells defined by study, test, and children's age. Results The original search identified 524 hits. In the end, 22 studies met the inclusion criteria for review. The observation period was between 1972 and 2015. Fifteen of the 22 studies used tests for cardiorespiratory endurance, eight for relative muscle strength, eleven for proxies of muscle power, and eight for speed. Measures of cardiorespiratory endurance exhibited a large initial increase and an equally large subsequent decrease, but the decrease appears to have reached a floor for all children between 2010 and 2015. Measures of relative muscle strength showed a general trend towards a small increase. Measures of proxies of muscle power indicated an overall small negative quadratic trend. For measures of speed, a small-to-medium increase was observed in recent years. Limitations Biological maturity was not considered in the analysis because biological maturity was not reported in most included studies. Conclusions Negative secular trends were particularly found for cardiorespiratory endurance between 1986 and 2010-12, irrespective of sex. Relative muscle strength and speed showed small increases while proxies of muscle power declined. Although the negative trend in cardiorespiratory endurance appears to have reached a floor in recent years, because of its association with markers of health, we recommend further initiatives in PA and fitness promotion for children and adolescents. More specifically, public health efforts should focus on exercise that increases cardiorespiratory endurance to prevent adverse health effects (i.e.
, overweight and obesity) and muscle strength to lay a foundation for motor skill learning. Y1 - 2020 U6 - https://doi.org/10.1007/s40279-020-01373-x SN - 0112-1642 SN - 1179-2035 VL - 51 IS - 2 SP - 303 EP - 320 PB - Springer CY - Northcote ER - TY - JOUR A1 - Bangeow, Petjo A1 - Rapp, Michael A. T1 - Beurteilung und Nutzung der 2016 reformierten Psychotherapierichtlinie T1 - Assessment and use of 2016 reformed psychotherapeutic guideline BT - Teil II : Ost-West- und Stadt-Land-Vergleich BT - part II : comparing Eastern and Western Germany as well as urban and rural areas JF - Psychiatrische Praxis : Sozialpsychiatrie, klinische Psychiatrie, public mental health, Versorgungsforschung N2 - Ziel der Studie Dieser Artikel untersucht, inwiefern sich die 2016 reformierte Richtlinie im Stadt-Land- sowie im Ost-West-Vergleich auf die ambulante psychotherapeutische Arbeit und Versorgung auswirkt. Methodik Eine Onlineumfrage unter vertragsärztlich tätigen TherapeutInnen wurde durchgeführt. Die Fragen bezogen sich auf verschiedene Neuerungen in der Richtlinie. Ergebnisse Unabhängig von der Region schätzten die Befragten ein, dass die Reform zu keiner verbesserten Versorgung führte. Im Westen und in der Stadt tätige TherapeutInnen verwiesen PatientInnen nach der Sprechstunde öfter an andere Psychotherapiepraxen, im Osten und auf dem Land tätige hingegen öfter auf andere Hilfeangebote. Schlussfolgerung Stärkere Anreize für die psychotherapeutische Tätigkeit auf dem Land sind zu schaffen. Abbaumaßnahmen der Ost-West-Ungleichheiten in der Versorgungsdichte scheinen nötig. N2 - Objective This article investigated whether or not the reformed psychotherapeutic guideline had different effects on outpatient psychotherapeutic work and services comparing urban and rural areas as well as eastern and western Germany. Methods An online survey of psychotherapists was conducted. The survey included questions on various innovations within the reformed guideline. Results Regardless of region, therapists stated overall that the reform has not led to improved psychotherapeutic care. Therapists in the West and in urban areas referred more patients to other psychotherapeutic practices after their consultation. Therapists in the East and in rural areas referred more patients to other institutions and services. Conclusions Psychotherapeutic work in rural areas should be better incentivized. Interventions to reduce east-west inequalities in the density of service provision seem to be necessary. KW - Psychotherapierichtlinie KW - Ostdeutschland KW - Westdeutschland KW - Stadt-Land-Vergleich KW - psychotherapy guidelines KW - Eastern-Western Germany KW - urban-rural KW - comparison Y1 - 2020 U6 - https://doi.org/10.1055/a-1045-9820 SN - 0303-4259 SN - 1439-0876 VL - 47 IS - 07 SP - 383 EP - 387 PB - Thieme CY - Stuttgart ER - TY - JOUR A1 - Brecht, Pia A1 - Beckendorf, Claudia A1 - Mayer, Frank T1 - Cardiac remodeling in child and adolescent athletes in association with sport discipline and sex JF - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine N2 - Continuous high training loads are associated with structural cardiac adaptations and development of an athletic heart in adult athletes, especially in sport disciplines with high dynamic training components. In child and adolescent athletes these effects are increasingly reported. However, study populations are still very small. Y1 - 2020 U6 - https://doi.org/10.1249/01.mss.0000679076.53908.d0 SN - 0195-9131 SN - 1530-0315 VL - 52 IS - 17 SP - 472 EP - 473 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Adnan, Hassan Sami A1 - Matthews, Sam A1 - Hackl, M. A1 - Das, P. P. A1 - Manaswini, Manisha A1 - Gadamsetti, S. A1 - Filali, Maroua A1 - Owoyele, Babajide A1 - Santuber, Joaquín A1 - Edelman, Jonathan T1 - Human centered AI design for clinical monitoring and data management JF - European journal of public health : official journal of the European Health Association N2 - In clinical settings, significant resources are spent on data collection and monitoring patients' health parameters to improve decision-making and provide better care. With increased digitization, the healthcare sector is shifting towards implementing digital technologies for data management and in administration. New technologies offer better treatment opportunities and streamline clinical workflow, but the complexity can cause ineffectiveness, frustration, and errors. To address this, we believe digital solutions alone are not sufficient. Therefore, we take a human-centred design approach for AI development, and apply systems engineering methods to identify system leverage points. We demonstrate how automation enables monitoring clinical parameters, using existing non-intrusive sensor technology, resulting in more resources toward patient care. Furthermore, we provide a framework on digitization of clinical data for integration with data management. Y1 - 2020 U6 - https://doi.org/10.1093/eurpub/ckaa165.225 SN - 1101-1262 SN - 1464-360X VL - 30 IS - 5 SP - V86 EP - V86 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Khajooei, Mina A1 - Wochatz, Monique A1 - Baritello, Omar A1 - Mayer, Frank T1 - Effects of shoes on children’s fundamental motor skills performance JF - Footwear science : official journal of the Footwear Biomechanics Group N2 - Progression or impediment of fundamental motor skills performance (FMSP) in children depends on internal and environmental factors. Shoes as an environmental constraint are believed to affect these movements as children showed to perform qualitatively better with sports shoes than flip-flop sandals. However, locomotor performance assessments based on biomechanical variables are limited. Therefore, the objective of this experiment was to assess the biomechanical effects of wearing shoes while performing fundamental motor skills in children. Barefoot and shod conditions were tested in healthy children between the age of 4 and 7 years. They were asked to perform basic and advanced motor skills including double-leg stance, horizontal jumps, walking as well as counter-movement jumps, single-leg stance and sprinting. Postural control and ground reaction data were measured with two embedded force plates. A 3D motion capture system was used to analyse the spatiotemporal parameters of walking and sprinting. Findings showed that the parameters of single- and double-leg stance, horizontal and counter-movement jump did not differ between barefoot and shod conditions. Most of the spatiotemporal variables including cadence, stride length, stride time, and contact time of walking and sprinting were statistically different between the barefoot and shod conditions. Consequently, tested shoes did not change performance and biomechanics of postural control and jumping tasks; however, the spatiotemporal gait parameters indicate changes in walking and sprinting characteristics with shoes in children. KW - Spatiotemporal KW - kinetics KW - jumping KW - stability KW - gait Y1 - 2019 U6 - https://doi.org/10.1080/19424280.2019.1696895 SN - 1942-4280 SN - 1942-4299 VL - 12 IS - 1 SP - 55 EP - 62 PB - Taylor & Francis CY - Abingdon ER - TY - JOUR A1 - Urbach, Dietmar A1 - Awiszus, Friedemann A1 - Leiß, Sven A1 - Venton, Tamsin A1 - De Specht, Alexander Vincent A1 - Apfelbacher, Christian T1 - Associations of medications with lower odds of typical COVID-19 symptoms BT - cross-sectional symptom surveillance study JF - JMIR public health and surveillance N2 - Background: As the COVID-19 pandemic continues to spread across the globe, the search for an effective medication to treat the symptoms of COVID-19 continues as well. It would be desirable to identify a medication that is already in use for another condition and whose side effect profile and safety data are already known and approved. Objective: The objective of this study was to evaluate the effect of different medications on typical COVID-19 symptoms by using data from an online surveillance survey. Methods: Between early April and late-July 2020, a total of 3654 individuals in Lower Saxony, Germany, participated in an online symptom-tracking survey conducted through the app covid-nein-danke.de. The questionnaire comprised items on typical COVID-19 symptoms, age range, gender, employment in patient-facing healthcare, housing status, postal code, previous illnesses, permanent medication, vaccination status, results of reverse transcription polymerase chain reaction (RT-PCR) and antibody tests for COVID-19 diagnosis, and consequent COVID-19 treatment if applicable. Odds ratio estimates with corresponding 95% CIs were computed for each medication and symptom by using logistic regression models. Results: Data analysis suggested a statistically significant inverse relationship between typical COVID-19 symptoms self-reported by the participants and self-reported statin therapy and, to a lesser extent, antihypertensive therapy. When COVID-19 diagnosis was based on restrictive symptom criteria (ie, presence of 4 out of 7 symptoms) or a positive RT-PCR test, a statistically significant association was found solely for statins (odds ratio 0.28, 95% CI 0.1-0.78). Conclusions: Individuals taking statin medication are more likely to have asymptomatic COVID-19, in which case they may be at an increased risk of transmitting the disease unknowingly. We suggest that the results of this study be incorporated into symptoms-based surveillance and decision-making protocols in regard to COVID-19 management. Whether statin therapy has a beneficial effect in combating COVID-19 cannot be deduced based on our findings and should be investigated by further study. KW - COVID-19 KW - SARS-CoV-2 KW - statins KW - antihypertensives KW - surveillance KW - hydroxymethyl-glutaryl-coenzyme A reductase inhibitors;online survey Y1 - 2020 U6 - https://doi.org/10.2196/22521 SN - 2369-2960 VL - 6 IS - 4 PB - JMIR Publications CY - Toronto ER -