TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Adam, R.
A1  - Aharonian, Felix A.
A1  - Benkhali, F. Ait
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arcaro, C.
A1  - Armand, C.
A1  - Ashkar, H.
A1  - Backes, M.
A1  - Martins, V. Barbosa
A1  - Barnard, M.
A1  - Becherini, Y.
A1  - Berge, D.
A1  - Bernloehr, K.
A1  - Bissaldi, E.
A1  - Blackwell, R.
A1  - Boettcher, M.
A1  - Boisson, C.
A1  - Bolmont, J.
A1  - Bonnefoy, S.
A1  - Bregeon, J.
A1  - Breuhaus, M.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Buechele, M.
A1  - Bulik, T.
A1  - Bylund, T.
A1  - Capasso, M.
A1  - Caroff, S.
A1  - Carosi, A.
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chand, T.
A1  - Chandra, S.
A1  - Chen, A.
A1  - Colafrancesco, S.
A1  - Curylo, M.
A1  - Davids, I. D.
A1  - Deil, C.
A1  - Devin, J.
A1  - deWilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Dmytriiev, A.
A1  - Donath, A.
A1  - Doroshenko, V
A1  - Dyks, J.
A1  - Egberts, Kathrin
A1  - Emery, G.
A1  - Ernenwein, J-P
A1  - Eschbach, S.
A1  - Feijen, K.
A1  - Fegan, S.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Funk, S.
A1  - Fussling, Matthias
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Gate, F.
A1  - Giavitto, G.
A1  - Giunti, L.
A1  - Glawion, D.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M-H
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, J. A.
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holch, T. L.
A1  - Holler, M.
A1  - Horns, D.
A1  - Huber, D.
A1  - Iwasaki, H.
A1  - Jamrozy, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jardin-Blicq, A.
A1  - Jung-Richardt, I
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Kluzniak, W.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kostunin, D.
A1  - Kreter, M.
A1  - Lamanna, G.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J-P
A1  - Leser, Eva
A1  - Levy, C.
A1  - Lohse, T.
A1  - Lypova, I
A1  - Mackey, J.
A1  - Majumdar, J.
A1  - Malyshev, D.
A1  - Marandon, V
A1  - Marcowith, Alexandre
A1  - Mares, A.
A1  - Mariaud, C.
A1  - Marti-Devesa, G.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Meintjes, P. J.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Moore, C.
A1  - Moulin, Emmanuel
A1  - Muller, J.
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Ndiyavala, H.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Ostrowski, M.
A1  - Oya, I
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Perennes, C.
A1  - Petrucci, P-O
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poireau, V
A1  - Noel, A. Priyana
A1  - Prokhorov, D. A.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Remy, Q.
A1  - Renaud, M.
A1  - Rieger, F.
A1  - Rinchiuso, L.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Ruiz-Velasco, E.
A1  - Sahakian, V
A1  - Sailer, S.
A1  - Saito, S.
A1  - Sanchez, D. A.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schussler, F.
A1  - Schulz, A.
A1  - Schutte, H. M.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Senniappan, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shiningayamwe, K.
A1  - Simoni, R.
A1  - Sinha, A.
A1  - Sol, H.
A1  - Specovius, A.
A1  - Spir-Jacob, M.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steppa, Constantin Beverly
A1  - Takahashi, T.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsirou, M.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Yang, R.
A1  - Yoneda, H.
A1  - Zacharias, M.
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Ziegler, A.
A1  - Zorn, J.
A1  - Zywucka, N.
A1  - de Palma, F.
A1  - Axelsson, M.
A1  - Roberts, O. J.
T1  - A very-high-energy component deep in the gamma-ray burst afterglow
JF  - Nature : the international weekly journal of science
N2  - Gamma-ray bursts (GRBs) are brief flashes of gamma-rays and are considered to be the most energetic explosive phenomena in the Universe(1). The emission from GRBs comprises a short (typically tens of seconds) and bright prompt emission, followed by a much longer afterglow phase. During the afterglow phase, the shocked outflow-produced by the interaction between the ejected matter and the circumburst medium-slows down, and a gradual decrease in brightness is observed(2). GRBs typically emit most of their energy via.-rays with energies in the kiloelectronvolt-to-megaelectronvolt range, but a few photons with energies of tens of gigaelectronvolts have been detected by space-based instruments(3). However, the origins of such high-energy (above one gigaelectronvolt) photons and the presence of very-high-energy (more than 100 gigaelectronvolts) emission have remained elusive(4). Here we report observations of very-high-energy emission in the bright GRB 180720B deep in the GRB afterglow-ten hours after the end of the prompt emission phase, when the X-ray flux had already decayed by four orders of magnitude. Two possible explanations exist for the observed radiation: inverse Compton emission and synchrotron emission of ultrarelativistic electrons. Our observations show that the energy fluxes in the X-ray and gamma-ray range and their photon indices remain comparable to each other throughout the afterglow. This discovery places distinct constraints on the GRB environment for both emission mechanisms, with the inverse Compton explanation alleviating the particle energy requirements for the emission observed at late times. The late timing of this detection has consequences for the future observations of GRBs at the highest energies.
Y1  - 2019
U6  - https://doi.org/10.1038/s41586-019-1743-9
SN  - 0028-0836
SN  - 1476-4687
VL  - 575
IS  - 7783
SP  - 464
EP  - +
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Adam, R.
A1  - Aharonian, Felix A.
A1  - Benkhali, F. Ait
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arcaro, C.
A1  - Armand, C.
A1  - Ashkar, H.
A1  - Backes, M.
A1  - Martins, V. Barbosa
A1  - Barnard, M.
A1  - Becherini, Y.
A1  - Berge, D.
A1  - Bernloehr, K.
A1  - Blackwell, R.
A1  - Böttcher, M.
A1  - Boisson, C.
A1  - Bolmont, J.
A1  - Bonnefoy, S.
A1  - Bregeon, J.
A1  - Breuhaus, M.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Büchele, M.
A1  - Bulik, T.
A1  - Bylund, T.
A1  - Capasso, M.
A1  - Caroff, S.
A1  - Carosi, A.
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chand, T.
A1  - Chandra, S.
A1  - Chen, A.
A1  - Colafrancesco, S.
A1  - Curylo, M.
A1  - Davids, I. D.
A1  - Deil, C.
A1  - Devin, J.
A1  - DeWilt, P.
A1  - Dirson, L.
A1  - Djannati-Ata, A.
A1  - Dmytriiev, A.
A1  - Donath, A.
A1  - Doroshenko, V
A1  - Dyks, J.
A1  - Egberts, Kathrin
A1  - Emery, G.
A1  - Ernenwein, J-P
A1  - Eschbach, S.
A1  - Feijen, K.
A1  - Fegan, S.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Funk, S.
A1  - Füßling, Matthias
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Gate, F.
A1  - Giavitto, G.
A1  - Glawion, D.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M-H
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holch, Tim Lukas
A1  - Holler, M.
A1  - Horns, D.
A1  - Huber, D.
A1  - Iwasaki, H.
A1  - Jamrozy, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jardin-Blicq, A.
A1  - Jung-Richardt, I
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Kluzniak, W.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kostunin, D.
A1  - Kraus, M.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J-P
A1  - Leser, Eva
A1  - Levy, C.
A1  - Lohse, T.
A1  - Lypova, I
A1  - Mackey, J.
A1  - Majumdar, J.
A1  - Malyshev, D.
A1  - Marandon, V
A1  - Marcowith, Alexandre
A1  - Mares, A.
A1  - Mariaud, C.
A1  - Marti-Devesa, G.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Meintjes, P. J.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Moore, C.
A1  - Moulin, Emmanuel
A1  - Muller, J.
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Ndiyavala, H.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Ostrowski, M.
A1  - Oya, I
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Perennes, C.
A1  - Petrucci, P-O
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poireau, V
A1  - Priyana Noel, A.
A1  - Prokhorov, D. A.
A1  - Prokoph, H.
A1  - Pühlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Remy, Q.
A1  - Renaud, M.
A1  - Rieger, F.
A1  - Rinchiuso, L.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Ruiz-Velasco, E.
A1  - Sahakian, V
A1  - Saito, S.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schüssler, F.
A1  - Schulz, A.
A1  - Schutte, H.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Senniappan, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shiningayamwe, K.
A1  - Simoni, R.
A1  - Sinha, A.
A1  - Sol, H.
A1  - Specovius, A.
A1  - Spir-Jacob, M.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steppa, Constantin Beverly
A1  - Takahashi, T.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsirou, M.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van Der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Yang, R.
A1  - Yoneda, H.
A1  - Zacharias, Michael
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Ziegler, A.
A1  - Zorn, J.
A1  - Zywucka, N.
A1  - Meyer, M.
T1  - Constraints on the emission region of 3C 279 during strong flares in 2014 and 2015 through VHE gamma-ray observations with HESS
JF  - Astronomy and astrophysics : an international weekly journal
N2  - The flat spectrum radio quasar 3C 279 is known to exhibit pronounced variability in the high-energy (100MeV < E < 100 GeV) gamma-ray band, which is continuously monitored with Fermi-LAT. During two periods of high activity in April 2014 and June 2015 target-of-opportunity observations were undertaken with the High Energy Stereoscopic System (H.E.S.S.) in the very-high-energy (VHE, E > 100 GeV) gamma-ray domain. While the observation in 2014 provides an upper limit, the observation in 2015 results in a signal with 8 : 7 sigma significance above an energy threshold of 66 GeV. No VHE variability was detected during the 2015 observations. The VHE photon spectrum is soft and described by a power-law index of 4.2 +/- 0.3. The H.E.S.S. data along with a detailed and contemporaneous multiwavelength data set provide constraints on the physical parameters of the emission region. The minimum distance of the emission region from the central black hole was estimated using two plausible geometries of the broad-line region and three potential intrinsic spectra. The emission region is confidently placed at r greater than or similar to 1 : 7 X 1017 cm from the black hole, that is beyond the assumed distance of the broad-line region. Time-dependent leptonic and lepto-hadronic one-zone models were used to describe the evolution of the 2015 flare. Neither model can fully reproduce the observations, despite testing various parameter sets. Furthermore, the H.E.S.S. data were used to derive constraints on Lorentz invariance violation given the large redshift of 3C 279.
KW  - radiation mechanisms: non-thermal
KW  - quasars: individual: 3C 279
KW  - galaxies: active
KW  - relativistic processes
Y1  - 2019
U6  - https://doi.org/10.1051/0004-6361/201935704
SN  - 1432-0746
VL  - 627
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Aharonian, Felix A.
A1  - Benkhali, F. Ait
A1  - Anguener, E. O.
A1  - Arakawa, M.
A1  - Arcaro, C.
A1  - Armand, C.
A1  - Ashkar, H.
A1  - Backes, M.
A1  - Martins, V. Barbosa
A1  - Barnard, M.
A1  - Becherini, Y.
A1  - Berge, D.
A1  - Bernloehr, K.
A1  - Blackwell, R.
A1  - Boettcher, M.
A1  - Boisson, C.
A1  - Bolmont, J.
A1  - Bonnefoy, S.
A1  - Bregeon, J.
A1  - Breuhaus, M.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Buechele, M.
A1  - Bulik, T.
A1  - Bylund, T.
A1  - Capasso, M.
A1  - Caroff, S.
A1  - Carosi, A.
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chakraborty, N.
A1  - Chand, T.
A1  - Chandra, S.
A1  - Chaves, R. C. G.
A1  - Chen, A.
A1  - Colafrancesco, S.
A1  - Curylo, M.
A1  - Davids, I. D.
A1  - Deil, C.
A1  - Devin, J.
A1  - de Wilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Dmytriiev, A.
A1  - Donath, A.
A1  - Doroshenko, V
A1  - Dyks, J.
A1  - Egberts, Kathrin
A1  - Emery, G.
A1  - Ernenwein, J-p
A1  - Eschbach, S.
A1  - Feijen, K.
A1  - Fegan, S.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Funk, S.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Gate, F.
A1  - Giavitto, G.
A1  - Glawion, D.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M-H
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holch, Tim Lukas
A1  - Holler, M.
A1  - Horns, D.
A1  - Huber, D.
A1  - Iwasaki, H.
A1  - Jamrozy, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jung-Richardt, I
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Kluzniak, W.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kostunin, D.
A1  - Kraus, M.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J-P
A1  - Leser, Eva
A1  - Levy, C.
A1  - Lohse, T.
A1  - Lopez-Coto, R.
A1  - Lypova, I
A1  - Mackey, J.
A1  - Majumdar, J.
A1  - Malyshev, D.
A1  - Marandon, V
A1  - Marcowith, Alexandre
A1  - Mares, A.
A1  - Mariaud, C.
A1  - Marti-Devesa, G.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Meintjes, P. J.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Muller, J.
A1  - Moore, C.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Ndiyavala, H.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Ostrowski, M.
A1  - Oya, I
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Perennes, C.
A1  - Petrucci, P-O
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poireau, V
A1  - Noel, A. Priyana
A1  - Prokhorov, D. A.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Remy, Q.
A1  - Renaud, M.
A1  - Rieger, F.
A1  - Rinchiuso, L.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Ruiz-Velasco, E.
A1  - Sahakian, V
A1  - Saito, S.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schussler, F.
A1  - Schulz, A.
A1  - Schutte, H.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Senniappan, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shiningayamwe, K.
A1  - Simoni, R.
A1  - Sinha, A.
A1  - Sol, H.
A1  - Specovius, A.
A1  - Spir-Jacob, M.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steppa, Constantin Beverly
A1  - Takahashi, T.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsirou, M.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Yang, R.
A1  - Yoneda, H.
A1  - Zacharias, M.
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Ziegler, A.
A1  - Zorn, J.
A1  - Zywucka, N.
A1  - Maxted, N.
T1  - Upper limits on very-high-energy gamma-ray emission from core-collapse supernovae observed with H.E.S.S.
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Young core-collapse supernovae with dense-wind progenitors may be able to accelerate cosmic-ray hadrons beyond the knee of the cosmic-ray spectrum, and this may result in measurable gamma-ray emission. We searched for gamma-ray emission from ten super- novae observed with the High Energy Stereoscopic System (H.E.S.S.) within a year of the supernova event. Nine supernovae were observed serendipitously in the H.E.S.S. data collected between December 2003 and December 2014, with exposure times ranging from 1.4 to 53 h. In addition we observed SN 2016adj as a target of opportunity in February 2016 for 13 h. No significant gamma-ray emission has been detected for any of the objects, and upper limits on the >1 TeV gamma-ray flux of the order of similar to 10(-13) cm(-)(2)s(-1) are established, corresponding to upper limits on the luminosities in the range similar to 2 x 10(39) to similar to 1 x 10(42) erg s(-1). These values are used to place model-dependent constraints on the mass-loss rates of the progenitor stars, implying upper limits between similar to 2 x 10(-5) and similar to 2 x 10(-3) M-circle dot yr(-1) under reasonable assumptions on the particle acceleration parameters.
KW  - gamma rays: general
KW  - supernovae: general
KW  - cosmic rays
Y1  - 2019
U6  - https://doi.org/10.1051/0004-6361/201935242
SN  - 1432-0746
VL  - 626
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Aharonian, Felix A.
A1  - Benkhali, F. Ait
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arcaro, C.
A1  - Armand, C.
A1  - Arrieta, M.
A1  - Backes, M.
A1  - Barnard, M.
A1  - Becherini, Y.
A1  - Tjus, J. Becker
A1  - Berge, D.
A1  - Bernhard, S.
A1  - Bernloehr, K.
A1  - Blackwell, R.
A1  - Bottcher, M.
A1  - Boisson, C.
A1  - Bolmont, J.
A1  - Bonnefoy, S.
A1  - Bordas, Pol
A1  - Bregeon, J.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Buechele, M.
A1  - Bulik, T.
A1  - Bylund, T.
A1  - Capasso, M.
A1  - Caroff, S.
A1  - Carosi, A.
A1  - Cerruti, M.
A1  - Chakraborty, N.
A1  - Chandra, S.
A1  - Chaves, R. C. G.
A1  - Chen, A.
A1  - Colafrancesco, S.
A1  - Condon, B.
A1  - Davids, I. D.
A1  - Deil, C.
A1  - Devin, J.
A1  - deWilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Dmytriiev, A.
A1  - Donath, A.
A1  - Doroshenko, V
A1  - Dyks, J.
A1  - Egberts, Kathrin
A1  - Emery, G.
A1  - Ernenwein, J-P
A1  - Eschbach, S.
A1  - Fegan, S.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Funk, S.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Gate, F.
A1  - Giavitto, G.
A1  - Glawion, D.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M-H
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holch, Tim Lukas
A1  - Holler, M.
A1  - Horns, D.
A1  - Huber, D.
A1  - Iwasaki, H.
A1  - Jacholkowska, A.
A1  - Jamrozy, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jouvin, L.
A1  - Jung-Richardt, I
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Kerszberg, D.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Kluzniak, W.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Kraus, M.
A1  - Kruger, P. P.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lefaucheur, J.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J-P
A1  - Leser, Eva
A1  - Lohse, T.
A1  - Lorentz, M.
A1  - Lopez-Coto, R.
A1  - Lypova, I
A1  - Malyshev, D.
A1  - Marandon, V
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marti-Devesa, G.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Meintjes, P. J.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Ndiyavala, H.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Ostrowski, M.
A1  - Oya, I
A1  - Padovani, M.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Perennes, C.
A1  - Petrucci, P-O
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poireau, V
A1  - Noel, A. Priyana
A1  - Prokhorov, D.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - Rieger, F.
A1  - Rinchiuso, L.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Ruiz-Velasco, E.
A1  - Sahakian, V
A1  - Saito, S.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schussler, F.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Senniappan, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shilon, I
A1  - Shiningayamwe, K.
A1  - Simoni, R.
A1  - Sinha, A.
A1  - Sol, H.
A1  - Spanier, F.
A1  - Specovius, A.
A1  - Spir-Jacob, M.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steppa, Constantin Beverly
A1  - Takahashi, T.
A1  - Tavernet, J-P
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tibaldo, L.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsirou, M.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - Wagner, R. M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Yang, R.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zefi, F.
A1  - Ziegler, A.
A1  - Zorn, J.
A1  - Zywucka, N.
T1  - The 2014TeV gamma-Ray Flare of Mrk 501 Seen with HESS
BT  - Temporal and Spectral Constraints on Lorentz Invariance Violation
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - The blazar Mrk 501 (z = 0.034) was observed at very-high-energy (VHE, E greater than or similar to 100 GeV) gamma-ray wavelengths during a bright flare on the night of 2014 June 23-24 (MJD 56832) with the H.E.S.S. phase-II array of Cherenkov telescopes. Data taken that night by H.E.S.S. at large zenith angle reveal an exceptional number of gamma-ray photons at multi-TeV energies, with rapid flux variability and an energy coverage extending significantly up to 20 TeV. This data set is used to constrain Lorentz invariance violation (LIV) using two independent channels: a temporal approach considers the possibility of an energy dependence in the arrival time of gamma-rays, whereas a spectral approach considers the possibility of modifications to the interaction of VHE gamma-rays with extragalactic background light (EBL) photons. The non-detection of energy-dependent time delays and the non-observation of deviations between the measured spectrum and that of a supposed power-law intrinsic spectrum with standard EBL attenuation are used independently to derive strong constraints on the energy scale of LIV (E-QG) in the subluminal scenario for linear and quadratic perturbations in the dispersion relation of photons. For the case of linear perturbations, the 95% confidence level limits obtained are E-QG,E-1 > 3.6 x 10(17) GeV using the temporal approach and E-QG,E-1 > 2.6 x 10(19) GeV using the spectral approach. For the case of quadratic perturbations, the limits obtained are E-QG,E-2 > 8.5 x 10(10) GeV using the temporal approach and E-QG,E-2 > 7.8 x 10(11) GeV using the spectral approach.
KW  - astroparticle physics
KW  - BL Lacertae objects: individual (Mrk 501)
KW  - gamma rays: galaxies
Y1  - 2019
U6  - https://doi.org/10.3847/1538-4357/aaf1c4
SN  - 0004-637X
SN  - 1538-4357
VL  - 870
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Aharonian, Felix A.
A1  - Benkhali, F. Ait
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arcaro, C.
A1  - Armand, C.
A1  - Arrieta, M.
A1  - Backes, M.
A1  - Barnard, M.
A1  - Becherini, Y.
A1  - Tjus, J. Becker
A1  - Berge, D.
A1  - Bernloehr, K.
A1  - Blackwell, R.
A1  - Bottcher, M.
A1  - Boisson, C.
A1  - Bolmont, J.
A1  - Bonnefoy, S.
A1  - Bordas, Pol
A1  - Bregeon, J.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Buchele, M.
A1  - Bulik, T.
A1  - Bylund, T.
A1  - Capasso, M.
A1  - Caroff, S.
A1  - Carosi, A.
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chakraborty, N.
A1  - Chand, T.
A1  - Chandra, S.
A1  - Chaves, R. C. G.
A1  - Chen, A.
A1  - Colafrancesco, S.
A1  - Condon, B.
A1  - Davids, I. D.
A1  - Deil, C.
A1  - Devin, J.
A1  - deWilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Dmytriiev, A.
A1  - Donath, A.
A1  - Doroshenko, V.
A1  - Dyks, J.
A1  - Egberts, Kathrin
A1  - Emery, G.
A1  - Ernenwein, J. -P.
A1  - Eschbach, S.
A1  - Fegan, S.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Funk, S.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Gate, F.
A1  - Giavitto, G.
A1  - Glawion, D.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M. -H.
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holch, Tim Lukas
A1  - Holler, M.
A1  - Horns, D.
A1  - Huber, D.
A1  - Iwasaki, H.
A1  - Jacholkowska, A.
A1  - Jamrozy, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jouvin, L.
A1  - Jung-Richardt, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Kluzniak, W.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Kraus, M.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lefaucheur, J.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Leser, Eva
A1  - Lohse, T.
A1  - Lopez-Coto, R.
A1  - Lorentz, M.
A1  - Lypova, I.
A1  - Malyshev, D.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marti-Devesa, G.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Meintjes, P. J.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Moore, C.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Ndiyavala, H.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Perennes, C.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poireau, V.
A1  - Noel, A. Priyana
A1  - Prokhorov, D. A.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - Rieger, F.
A1  - Rinchiuso, L.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Ruiz-Velasco, E.
A1  - Sahakian, V.
A1  - Saito, S.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schussler, F.
A1  - Schulz, A.
A1  - Schutte, H.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Senniappan, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shilon, I.
A1  - Shiningayamwe, K.
A1  - Simoni, R.
A1  - Sinha, A.
A1  - Sol, H.
A1  - Specovius, A.
A1  - Spir-Jacob, M.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steppa, Constantin Beverly
A1  - Takahashi, T.
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsirou, M.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - Wagner, R. M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Yang, R.
A1  - Yoneda, H.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Ziegler, A.
A1  - Zorn, J.
A1  - Zywucka, N.
T1  - H.E.S.S. observations of the flaring gravitationally lensed galaxy PKS 1830-211
JF  - Monthly notices of the Royal Astronomical Society
N2  - PKS 1830-211 is a known macrolensed quasar located at a redshift of z = 2.5. Its highenergy gamma-ray emission has been detected with the Fermi-Large Area Telescope (LAT) instrument and evidence for lensing was obtained by several authors from its high-energy data. Observations of PKS 1830-211 were taken with the High Energy Stereoscopic System (H.E.S.S.) array of Imaging Atmospheric Cherenkov Telescopes in 2014 August, following a flare alert by the Fermi-LAT Collaboration. The H.E.S.S observations were aimed at detecting a gamma-ray flare delayed by 20-27 d from the alert flare, as expected from observations at other wavelengths. More than 12 h of good-quality data were taken with an analysis threshold of similar to 67 GeV. The significance of a potential signal is computed as a function of the date and the average significance over the whole period. Data are compared to simultaneous observations by Fermi-LAT. No photon excess or significant signal is detected. An upper limit on PKS 1830-211 flux above 67 GeV is computed and compared to the extrapolation of the Fermi-LAT flare spectrum.
KW  - gravitational lensing: strong
KW  - diffuse radiation
KW  - gamma-rays: galaxies
Y1  - 2019
U6  - https://doi.org/10.1093/mnras/stz1031
SN  - 0035-8711
SN  - 1365-2966
VL  - 486
IS  - 3
SP  - 3886
EP  - 3891
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Aharonian, Felix A.
A1  - Benkhali, F. Ait
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arcaro, C.
A1  - Armand, C.
A1  - Arrieta, M.
A1  - Backes, M.
A1  - Barnard, M.
A1  - Becherini, Y.
A1  - Tjus, J. Becker
A1  - Berge, D.
A1  - Bernloehr, K.
A1  - Blackwell, R.
A1  - Bottcher, M.
A1  - Boisson, C.
A1  - Bolmont, J.
A1  - Bonnefoy, S.
A1  - Bordas, Pol
A1  - Bregeon, J.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Buechele, M.
A1  - Bulik, T.
A1  - Bylund, T.
A1  - Capasso, M.
A1  - Caroff, S.
A1  - Carosi, A.
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chakraborty, N.
A1  - Chand, T.
A1  - Chandra, S.
A1  - Chaves, R. C. G.
A1  - Chen, A.
A1  - Colafrancesco, S.
A1  - Condon, B.
A1  - Davids, I. D.
A1  - Deil, C.
A1  - Devin, J.
A1  - deWilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Dmytriiev, A.
A1  - Donath, A.
A1  - Doroshenko, V
A1  - Dyks, J.
A1  - Egberts, Kathrin
A1  - Emery, G.
A1  - Ernenwein, J-P
A1  - Eschbach, S.
A1  - Fegan, S.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Funk, S.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Gate, F.
A1  - Giavitto, G.
A1  - Glawion, D.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M-H
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holch, Tim Lukas
A1  - Holler, M.
A1  - Horns, D.
A1  - Huber, D.
A1  - Iwasaki, H.
A1  - Jacholkowska, A.
A1  - Jamrozy, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jouvin, L.
A1  - Jung-Richardt, I
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Kerszberg, D.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Kluzniak, W.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kraus, M.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lefaucheur, J.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J-P
A1  - Leser, Eva
A1  - Lohse, T.
A1  - Lopez-Coto, R.
A1  - Lypova, I
A1  - Malyshev, D.
A1  - Marandon, V
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marti-Devesa, G.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Meintjes, P. J.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Moore, C.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Ndiyavala, H.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Ostrowski, M.
A1  - Oya, I
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Perennes, C.
A1  - Petrucci, P-O
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poireau, V
A1  - Noel, A. Priyana
A1  - Prokhorov, D. A.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - Rieger, F.
A1  - Rinchiuso, L.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Ruiz-Velasco, E.
A1  - Sahakian, V
A1  - Saito, S.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schussler, F.
A1  - Schulz, A.
A1  - Schutte, H.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Senniappan, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shilon, I
A1  - Shiningayamwe, K.
A1  - Simoni, R.
A1  - Sinha, A.
A1  - Sol, H.
A1  - Specovius, A.
A1  - Spir-Jacob, M.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steppa, Constantin Beverly
A1  - Takahashi, T.
A1  - Tavernet, J-P
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tibaldo, L.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsirou, M.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - Wagner, R. M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Yang, R.
A1  - Yoneda, H.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zefi, F.
A1  - Ziegler, A.
A1  - Zorn, J.
A1  - Zywucka, N.
T1  - Particle transport within the pulsar wind nebula HESS J1825-137
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Context. We present a detailed view of the pulsar wind nebula (PWN) HESS J1825-137. We aim to constrain the mechanisms dominating the particle transport within the nebula, accounting for its anomalously large size and spectral characteristics. Aims. The nebula was studied using a deep exposure from over 12 years of H.E.S.S. I operation, together with data from H.E.S.S. II that improve the low-energy sensitivity. Enhanced energy-dependent morphological and spatially resolved spectral analyses probe the very high energy (VHE, E > 0.1 TeV) gamma-ray properties of the nebula. Methods. The nebula emission is revealed to extend out to 1.5 degrees from the pulsar, similar to 1.5 times farther than previously seen, making HESS J1825-137, with an intrinsic diameter of similar to 100 pc, potentially the largest gamma-ray PWN currently known. Characterising the strongly energy-dependent morphology of the nebula enables us to constrain the particle transport mechanisms. A dependence of the nebula extent with energy of R proportional to E alpha with alpha = -0.29 +/- 0.04(stat) +/- 0.05(sys) disfavours a pure diffusion scenario for particle transport within the nebula. The total gamma-ray flux of the nebula above 1 TeV is found to be (1.12 +/- 0.03(stat) +/- 0.25(sys)) +/- 10(-11) cm(-2) s(-1), corresponding to similar to 64% of the flux of the Crab nebula. Results. HESS J1825-137 is a PWN with clearly energy-dependent morphology at VHE gamma-ray energies. This source is used as a laboratory to investigate particle transport within intermediate-age PWNe. Based on deep observations of this highly spatially extended PWN, we produce a spectral map of the region that provides insights into the spectral variation within the nebula.
KW  - gamma rays: general
KW  - acceleration of particles
KW  - convection
KW  - diffusion
KW  - pulsars: general
Y1  - 2019
U6  - https://doi.org/10.1051/0004-6361/201834335
SN  - 1432-0746
VL  - 621
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Aharonian, Felix A.
A1  - Benkhali, F. Ait
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arcaro, C.
A1  - Armand, C.
A1  - Backes, M.
A1  - Barnard, M.
A1  - Becherini, Y.
A1  - Berge, D.
A1  - Bernloehr, K.
A1  - Blackwell, R.
A1  - Bottcher, M.
A1  - Boisson, C.
A1  - Bolmont, J.
A1  - Bonnefoy, S.
A1  - Bregeon, J.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Buechele, M.
A1  - Bulik, T.
A1  - Bylund, T.
A1  - Capasso, M.
A1  - Caroff, S.
A1  - Carosi, A.
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chakraborty, N.
A1  - Chand, T.
A1  - Chandra, S.
A1  - Chaves, R. C. G.
A1  - Chen, A.
A1  - Colafrancesco, S.
A1  - Condon, B.
A1  - Davids, I. D.
A1  - Deil, C.
A1  - Devin, J.
A1  - deWilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Dmytriiev, A.
A1  - Donath, A.
A1  - Doroshenko, V
A1  - Dyks, J.
A1  - Egberts, Kathrin
A1  - Emery, G.
A1  - Ernenwein, J-P
A1  - Eschbach, S.
A1  - Feijen, K.
A1  - Fegan, S.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Funk, S.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Gate, F.
A1  - Giavitto, G.
A1  - Glawion, D.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M-H
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holch, Tim Lukas
A1  - Holler, M.
A1  - Horns, D.
A1  - Huber, D.
A1  - Iwasaki, H.
A1  - Jacholkowska, A.
A1  - Jamrozy, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jouvin, L.
A1  - Jung-Richardt, I
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Kluzniak, W.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kostunin, D.
A1  - Kraus, M.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J-P
A1  - Leser, Eva
A1  - Lohse, T.
A1  - Lopez-Coto, R.
A1  - Lypova, I
A1  - Malyshev, D.
A1  - Marandon, V
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marti-Devesa, G.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Meintjes, P. J.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Moore, C.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Ndiyavala, H.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Ostrowski, M.
A1  - Oya, I
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Perennes, C.
A1  - Petrucci, P-O
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poireau, V
A1  - Noel, A. Priyana
A1  - Prokhorov, D. A.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - Rieger, F.
A1  - Rinchiuso, L.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Ruiz-Velasco, E.
A1  - Sahakian, V
A1  - Saito, S.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schussler, F.
A1  - Schulz, A.
A1  - Schutte, H.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Senniappan, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shilon, I
A1  - Shiningayamwe, K.
A1  - Simoni, R.
A1  - Sinha, A.
A1  - Sol, H.
A1  - Specovius, A.
A1  - Spir-Jacob, M.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steppa, Constantin Beverly
A1  - Takahashi, T.
A1  - Tavernet, J-P
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tibaldo, Luigi
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsirou, M.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Yang, R.
A1  - Yoneda, H.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Ziegler, A.
A1  - Zorn, J.
A1  - Zywucka, N.
T1  - H.E.S.S. and Suzaku observations of the Vela X pulsar wind nebula
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Context. Pulsar wind nebulae (PWNe) represent the most prominent population of Galactic very-high-energy gamma-ray sources and are thought to be an efficient source of leptonic cosmic rays. Vela X is a nearby middle-aged PWN, which shows bright X-ray and TeV gamma-ray emission towards an elongated structure called the cocoon. Aims. Since TeV emission is likely inverse-Compton emission of electrons, predominantly from interactions with the cosmic microwave background, while X-ray emission is synchrotron radiation of the same electrons, we aim to derive the properties of the relativistic particles and of magnetic fields with minimal modelling. Methods. We used data from the Suzaku XIS to derive the spectra from three compact regions in Vela X covering distances from 0.3 to 4 pc from the pulsar along the cocoon. We obtained gamma-ray spectra of the same regions from H.E.S.S. observations and fitted a radiative model to the multi-wavelength spectra. Results. The TeV electron spectra and magnetic field strengths are consistent within the uncertainties for the three regions, with energy densities of the order 10(-12) erg cm(-3). The data indicate the presence of a cutoff in the electron spectrum at energies of similar to 100 TeV and a magnetic field strength of similar to 6 mu G. Constraints on the presence of turbulent magnetic fields are weak. Conclusions. The pressure of TeV electrons and magnetic fields in the cocoon is dynamically negligible, requiring the presence of another dominant pressure component to balance the pulsar wind at the termination shock. Sub-TeV electrons cannot completely account for the missing pressure, which may be provided either by relativistic ions or from mixing of the ejecta with the pulsar wind. The electron spectra are consistent with expectations from transport scenarios dominated either by advection via the reverse shock or by diffusion, but for the latter the role of radiative losses near the termination shock needs to be further investigated in the light of the measured cutoff energies. Constraints on turbulent magnetic fields and the shape of the electron cutoff can be improved by spectral measurements in the energy range greater than or similar to 10 keV.
KW  - stars: winds, outflows
KW  - gamma rays: stars
KW  - radiation mechanisms: non-thermal
KW  - acceleration of particles
KW  - pulsars: individual: PSR B0833-45
Y1  - 2019
U6  - https://doi.org/10.1051/0004-6361/201935458
SN  - 1432-0746
VL  - 627
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Abebe, Zeweter
A1  - Haki, Gulelat Desse
A1  - Schweigert, Florian J.
A1  - Henkel, Ina M.
A1  - Baye, Kaleab
T1  - Low breastmilk vitamin A concentration is prevalent in rural Ethiopia
JF  - European journal of clinical nutrition
N2  - Background There is scant information on the breastmilk vitamin A (BMVA) concentration of lactating women in developing countries, partly due to lack of methods applicable in-field. Objective To assess BMVA concentrations of samples collected from lactating women of children aged 6-23 months, in Mecha district, Ethiopia. Subjects/methods Data on socio-demographic and anthropometric characteristics were collected from randomly selected lactating women (n = 104). Breast milk samples were collected and vitamin A concentrations were analyzed using HPLC and iCheck FLUORO then the two measurements were compared. Results The prevalence of underweight (BMI < 18.5 kg/m(2)) among lactating women was 17%. Seventy six percent of the BMVA values were < 1.05 mu mol/l and 81% were < 8 mu g/g fat. The mean BMVA concentration accounted to 41% of the estimated average value for mothers in developing countries. The BMVA values from HPLC and iCheck were correlated (r = 0.59, p = < 0.001), but it was not strong. Conclusions The result indicates the low vitamin A status of the lactating women and their children. It further indicates that intake assessments should not use average BMVA composition. The possibility of using iCheck for monitoring interventions designed to improve vitamin A status of lactating women with low BMVA requires further investigation.
Y1  - 2019
U6  - https://doi.org/10.1038/s41430-018-0334-4
SN  - 0954-3007
SN  - 1476-5640
VL  - 73
IS  - 8
SP  - 1110
EP  - 1116
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Abeysekara, A. U.
A1  - Archer, A.
A1  - Benbow, Wystan
A1  - Bird, Ralph
A1  - Brill, A.
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Calderon-Madera, D.
A1  - Christiansen, J. L.
A1  - Cui, W.
A1  - Daniel, M. K.
A1  - Falcone, A.
A1  - Feng, Q.
A1  - Fernandez-Alonso, M.
A1  - Finley, J. P.
A1  - Fortson, Lucy
A1  - Furniss, Amy
A1  - Gent, A.
A1  - Giuri, C.
A1  - Gueta, O.
A1  - Hanna, David
A1  - Hassan, T.
A1  - Hervet, Oliver
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Johnson, Caitlin A.
A1  - Kaaret, P.
A1  - Kertzman, M.
A1  - Kieda, David
A1  - Krause, Maria
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Maier, Gernot
A1  - Moriarty, P.
A1  - Mukherjee, Reshmi
A1  - Nievas-Rosillo, M.
A1  - Ong, R. A.
A1  - Pfrang, Konstantin Johannes
A1  - Pohl, Martin
A1  - Prado, R. R.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Ribeiro, D.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rovero, A. C.
A1  - Sadeh, Iftach
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Shahinyan, Karlen
A1  - Sushch, Iurii
A1  - Svraka, T.
A1  - Weinstein, A.
A1  - Wells, R. M.
A1  - Wilcox, Patrick
A1  - Wilhelm, Alina
A1  - Williams, David Arnold
A1  - Williamson, T. J.
A1  - Zitzer, B.
T1  - Measurement of the Extragalactic Background Light Spectral Energy Distribution with VERITAS
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - The extragalactic background light (EBL), a diffuse photon field in the optical and infrared range, is a record of radiative processes over the universe?s history. Spectral measurements of blazars at very high energies (>100 GeV) enable the reconstruction of the spectral energy distribution (SED) of the EBL, as the blazar spectra are modified by redshift- and energy-dependent interactions of the gamma-ray photons with the EBL. The spectra of 14 VERITAS-detected blazars are included in a new measurement of the EBL SED that is independent of EBL SED models. The resulting SED covers an EBL wavelength range of 0.56?56 ?m, and is in good agreement with lower limits obtained by assuming that the EBL is entirely due to radiation from cataloged galaxies.
KW  - Extragalactic astronomy
KW  - Active galactic nuclei
KW  - Diffuse radiation
KW  - Cosmology
Y1  - 2019
U6  - https://doi.org/10.3847/1538-4357/ab4817
SN  - 0004-637X
SN  - 1538-4357
VL  - 885
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Adam, Berit
T1  - Öffentliches Rechnungswesen
JF  - Handbuch zur Verwaltungsreform
Y1  - 2019
SN  - 978-3-658-21562-0
SP  - 443
EP  - 456
PB  - Springer
CY  - Wiesbaden
ET  - 5., vollständig überarb. Aufl.
ER  - 
TY  - JOUR
A1  - Adem, Fozia A.
A1  - Kuete, Victor
A1  - Mbaveng, Armelle T.
A1  - Heydenreich, Matthias
A1  - Koch, Andreas
A1  - Ndakala, Albert
A1  - Irungu, Beatrice
A1  - Yenesew, Abiy
A1  - Efferth, Thomas
T1  - Cytotoxic flavonoids from two Lonchocarpus species
JF  - Natural Product Research
N2  - A new isoflavone, 4′-prenyloxyvigvexin A (1) and a new pterocarpan, (6aR,11aR)-3,8-dimethoxybitucarpin B (2) were isolated from the leaves of Lonchocarpus bussei and the stem bark of Lonchocarpus eriocalyx, respectively. The extract of L. bussei also gave four known isoflavones, maximaisoflavone H, 7,2′-dimethoxy-3′,4′-methylenedioxyisoflavone, 6,7,3′-trimethoxy-4′,5′-methylenedioxyisoflavone, durmillone; a chalcone, 4-hydroxylonchocarpin; a geranylated phenylpropanol, colenemol; and two known pterocarpans, (6aR,11aR)-maackiain and (6aR,11aR)-edunol. (6aR,11aR)-Edunol was also isolated from the stem bark of L. eriocalyx. The structures of the isolated compounds were elucidated by spectroscopy. The cytotoxicity of the compounds was tested by resazurin assay using drug-sensitive and multidrug-resistant cancer cell lines. Significant antiproliferative effects with IC50 values below 10 μM were observed for the isoflavones 6,7,3′-trimethoxy-4′,5′-methylenedioxyisoflavone and durmillone against leukemia CCRF-CEM cells; for the chalcone, 4-hydroxylonchocarpin and durmillone against its resistant counterpart CEM/ADR5000 cells; as well as for durmillone against the resistant breast adenocarcinoma MDA-MB231/BCRP cells and resistant gliobastoma U87MG.ΔEGFR cells.
KW  - Lonchocarpus bussei
KW  - Lonchocarpus eriocalyx
KW  - Leguminosae
KW  - isoflavone
KW  - pterocarpan
KW  - cytotoxicity
Y1  - 2019
U6  - https://doi.org/10.1080/14786419.2018.1462179
SN  - 1478-6419
SN  - 1478-6427
VL  - 33
IS  - 18
SP  - 2609
EP  - 2617
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Adem, Fozia A.
A1  - Mbaveng, Armelle T.
A1  - Kuete, Victor
A1  - Heydenreich, Matthias
A1  - Ndakala, Albert
A1  - Irungu, Beatrice
A1  - Yenesew, Abiy
A1  - Efferth, Thomas
T1  - Cytotoxicity of isoflavones and biflavonoids from Ormocarpum kirkii towards multi-factorial drug resistant cancer
JF  - Phytomedicine : international journal of phytotherapy and phytopharmacology
N2  - Background: While incidences of cancer are continuously increasing, drug resistance of malignant cells is observed towards almost all pharmaceuticals. Several isoflavonoids and flavonoids are known for their cytotoxicity towards various cancer cells. Methods: The cytotoxicity of compounds was determined based on the resazurin reduction assay. Caspases activation was evaluated using the caspase-Glo assay. Flow cytometry was used to analyze the cell cycle (propodium iodide (PI) staining), apoptosis (annexin V/PI staining), mitochondrial membrane potential (MMP) (JC-1) and reactive oxygen species (ROS) (H2DCFH-DA). CCRF-CEM leukemia cells were used as model cells for mechanistic studies. Results: Compounds 1, 2 and 4 displayed IC50 values below 20 mu M towards CCRF-CEM and CEM/ADR5000 leukemia cells, and were further tested towards a panel of 7 carcinoma cells. The IC50 values of the compounds against carcinoma cells varied from 16.90 mu M (in resistant U87MG.Delta EGFR glioblastoma cells) to 48.67 mu M (against HepG2 hepatocarcinoma cells) for 1, from 7.85 mu M (in U87MG.Delta EGFR cells) to 14.44 mu M (in resistant MDA-MB231/BCRP breast adenocarcinoma cells) for 2, from 4.96 mu M (towards U87MG.Delta EGFRcells) to 7.76 mu M (against MDA-MB231/BCRP cells) for 4, and from 0.07 mu M (against MDA-MB231 cells) to 2.15 mu M (against HepG2 cells) for doxorubicin. Compounds 2 and 4 induced apoptosis in CCRF-CEM cells mediated by MMP alteration and increased ROS production. Conclusion: The present report indicates that isoflavones and biflavonoids from Ormocarpum kirkii are cytotoxic compounds with the potential of being exploited in cancer chemotherapy. Compounds 2 and 4 deserve further studies to develop new anticancer drugs to fight sensitive and resistant cancer cell lines.
KW  - Apoptosis
KW  - Cancer
KW  - Ormocarpum kirkii
KW  - Isoflavone
KW  - Biflavonoid
KW  - Multi-drug resistance
Y1  - 2019
U6  - https://doi.org/10.1016/j.phymed.2019.152853
SN  - 0944-7113
SN  - 1618-095X
VL  - 58
PB  - Elsevier
CY  - München
ER  - 
TY  - JOUR
A1  - Agarwal, Ankit
A1  - Caesar, Levke
A1  - Marwan, Norbert
A1  - Maheswaran, Rathinasamy
A1  - Merz, Bruno
T1  - Network-based identification and characterization of teleconnections on different scales
JF  - Scientific Reports
N2  - Sea surface temperature (SST) patterns can – as surface climate forcing – affect weather and climate at large distances. One example is El Niño-Southern Oscillation (ENSO) that causes climate anomalies around the globe via teleconnections. Although several studies identified and characterized these teleconnections, our understanding of climate processes remains incomplete, since interactions and feedbacks are typically exhibited at unique or multiple temporal and spatial scales. This study characterizes the interactions between the cells of a global SST data set at different temporal and spatial scales using climate networks. These networks are constructed using wavelet multi-scale correlation that investigate the correlation between the SST time series at a range of scales allowing instantaneously deeper insights into the correlation patterns compared to traditional methods like empirical orthogonal functions or classical correlation analysis. This allows us to identify and visualise regions of – at a certain timescale – similarly evolving SSTs and distinguish them from those with long-range teleconnections to other ocean regions. Our findings re-confirm accepted knowledge about known highly linked SST patterns like ENSO and the Pacific Decadal Oscillation, but also suggest new insights into the characteristics and origins of long-range teleconnections like the connection between ENSO and Indian Ocean Dipole.
Y1  - 2019
U6  - https://doi.org/10.1038/s41598-019-45423-5
SN  - 2045-2322
VL  - 9
PB  - Macmillan Publishers Limited
CY  - London
ER  - 
TY  - JOUR
A1  - Aguado, Felicidad
A1  - Cabalar, Pedro
A1  - Fandinno, Jorge
A1  - Pearce, David
A1  - Perez, Gilberto
A1  - Vidal, Concepcion
T1  - Forgetting auxiliary atoms in forks
JF  - Artificial intelligence
N2  - In this work we tackle the problem of checking strong equivalence of logic programs that may contain local auxiliary atoms, to be removed from their stable models and to be forbidden in any external context. We call this property projective strong equivalence (PSE). It has been recently proved that not any logic program containing auxiliary atoms can be reformulated, under PSE, as another logic program or formula without them – this is known as strongly persistent forgetting. In this paper, we introduce a conservative extension of Equilibrium Logic and its monotonic basis, the logic of Here-and-There, in which we deal with a new connective ‘|’ we call fork. We provide a semantic characterisation of PSE for forks and use it to show that, in this extension, it is always possible to forget auxiliary atoms under strong persistence. We further define when the obtained fork is representable as a regular formula.
KW  - Answer set programming
KW  - Non-monotonic reasoning
KW  - Equilibrium logic
KW  - Denotational semantics
KW  - Forgetting
KW  - Strong equivalence
Y1  - 2019
U6  - https://doi.org/10.1016/j.artint.2019.07.005
SN  - 0004-3702
SN  - 1872-7921
VL  - 275
SP  - 575
EP  - 601
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Aguado, Felicidad
A1  - Cabalar, Pedro
A1  - Fandiño, Jorge
A1  - Pearce, David
A1  - Perez, Gilberto
A1  - Vidal-Peracho, Concepcion
T1  - Revisiting Explicit Negation in Answer Set Programming
JF  - Theory and practice of logic programming
KW  - Answer set programming
KW  - Non-monotonic reasoning
KW  - Equilibrium logic
KW  - Explicit negation
Y1  - 2019
U6  - https://doi.org/10.1017/S1471068419000267
SN  - 1471-0684
SN  - 1475-3081
VL  - 19
IS  - 5-6
SP  - 908
EP  - 924
PB  - Cambridge Univ. Press
CY  - New York
ER  - 
TY  - JOUR
A1  - Aichner, Bernhard
A1  - Makhmudov, Zafar
A1  - Rajabov, Iljomjon
A1  - Zhang, Qiong
A1  - Pausata, Francesco Salvatore R.
A1  - Werner, Martin
A1  - Heinecke, Liv
A1  - Kuessner, Marie L.
A1  - Feakins, Sarah J.
A1  - Sachse, Dirk
A1  - Mischke, Steffen
T1  - Hydroclimate in the Pamirs Was Driven by Changes in Precipitation-Evaporation Seasonality Since theLast Glacial Period
JF  - Geophysical research letters
N2  - The Central Asian Pamir Mountains (Pamirs) are a high-altitude region sensitive to climatic change, with only few paleoclimatic records available. To examine the glacial-interglacial hydrological changes in the region, we analyzed the geochemical parameters of a 31-kyr record from Lake Karakul and performed a set of experiments with climate models to interpret the results. delta D values of terrestrial biomarkers showed insolation-driven trends reflecting major shifts of water vapor sources. For aquatic biomarkers, positive delta D shifts driven by changes in precipitation seasonality were observed at ca. 31-30, 28-26, and 17-14 kyr BP. Multiproxy paleoecological data and modelling results suggest that increased water availability, induced by decreased summer evaporation, triggered higher lake levels during those episodes, possibly synchronous to northern hemispheric rapid climate events. We conclude that seasonal changes in precipitation-evaporation balance significantly influenced the hydrological state of a large waterbody such as Lake Karakul, while annual precipitation amount and inflows remained fairly constant.
KW  - climate
KW  - biomarker
KW  - geochemistry
KW  - modelling
KW  - paleoclimate
KW  - hydrology
Y1  - 2019
U6  - https://doi.org/10.1029/2019GL085202
SN  - 0094-8276
SN  - 1944-8007
VL  - 46
IS  - 23
SP  - 13972
EP  - 13983
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Al Nakeeb, Noah
A1  - Kochovski, Zdravko
A1  - Li, Tingting
A1  - Zhang, Youjia
A1  - Lu, Yan
A1  - Schmidt, Bernhard V. K. J.
T1  - Poly(ethylene glycol) brush-b-poly(N-vinylpyrrolidone)-based double hydrophilic block copolymer particles crosslinked via crystalline alpha-cyclodextrin domains
JF  - RSC Advances
N2  - Self-assembly of block copolymers is a significant area of polymer science. The self-assembly of completely water-soluble block copolymers is of particular interest, albeit a challenging task. In the present work the self-assembly of a linear-brush architecture block copolymer, namely poly(N-vinylpyrrolidone)-b-poly(oligoethylene glycol methacrylate) (PVP-b-POEGMA), in water is studied. Moreover, the assembled structures are crosslinked via alpha-CD host/guest complexation in a supramolecular way. The crosslinking shifts the equilibrium toward aggregate formation without switching off the dynamic equilibrium of double hydrophilic block copolymer (DHBC). As a consequence, the self-assembly efficiency is improved without extinguishing the unique DHBC self-assembly behavior. In addition, decrosslinking could be induced without a change in concentration by adding a competing complexation agent for alpha-CD. The self-assembly behavior was followed by DLS measurement, while the presence of the particles could be observed via cryo-TEM before and after crosslinking.
Y1  - 2019
U6  - https://doi.org/10.1039/c8ra10672j
SN  - 2046-2069
VL  - 9
IS  - 9
SP  - 4993
EP  - 5001
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Al-Halbouni, Djamil
A1  - Holohan, Eoghan P.
A1  - Taheri, Abbas
A1  - Watson, Robert A.
A1  - Polom, Ulrich
A1  - Schoepfer, Martin P. J.
A1  - Emam, Sacha
A1  - Dahm, Torsten
T1  - Distinct element geomechanical modelling of the formation of sinkhole clusters within large-scale karstic depressions
JF  - Solid earth
N2  - The 2-D distinct element method (DEM) code (PFC2D_V5) is used here to simulate the evolution of subsidence-related karst landforms, such as single and clustered sinkholes, and associated larger-scale depressions. Subsurface material in the DEM model is removed progressively to produce an array of cavities; this simulates a network of subsurface groundwater conduits growing by chemical/mechanical erosion. The growth of the cavity array is coupled mechanically to the gravitationally loaded surroundings, such that cavities can grow also in part by material failure at their margins, which in the limit can produce individual collapse sinkholes. Two end-member growth scenarios of the cavity array and their impact on surface subsidence were examined in the models: (1) cavity growth at the same depth level and growth rate; (2) cavity growth at progressively deepening levels with varying growth rates. These growth scenarios are characterised by differing stress patterns across the cavity array and its overburden, which are in turn an important factor for the formation of sinkholes and uvalalike depressions. For growth scenario (1), a stable compression arch is established around the entire cavity array, hindering sinkhole collapse into individual cavities and favouring block-wise, relatively even subsidence across the whole cavity array. In contrast, for growth scenario (2), the stress system is more heterogeneous, such that local stress concentrations exist around individual cavities, leading to stress interactions and local wall/overburden fractures. Consequently, sinkhole collapses occur in individual cavities, which results in uneven, differential subsidence within a larger-scale depression. Depending on material properties of the cavity-hosting material and the overburden, the larger-scale depression forms either by sinkhole coalescence or by widespread subsidence linked geometrically to the entire cavity array. The results from models with growth scenario (2) are in close agreement with surface morphological and subsurface geophysical observations from an evaporite karst area on the eastern shore of the Dead Sea.
Y1  - 2019
U6  - https://doi.org/10.5194/se-10-1219-2019
SN  - 1869-9510
SN  - 1869-9529
VL  - 10
IS  - 4
SP  - 1219
EP  - 1241
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Albers, Philip
A1  - Üstün, Suayib
A1  - Witzel, Katja
A1  - Kraner, Max Erdmund
A1  - Börnke, Frederik
T1  - A Remorin from Nicotiana benthamiana Interacts with the Pseudomonas Type-III Effector Protein HopZ1a and is Phosphorylated by the Immune-Related Kinase PBS1
JF  - Molecular Plant-Microbe Interactions
N2  - The plasma membrane (PM) is at the interface of plant-pathogen interactions and, thus, many bacterial type-III effector (T3E) proteins target membrane-associated processes to interfere with immunity. The Pseudomonas syringae T3E HopZ1a is a host cell PM-localized effector protein that has several immunity-associated host targets but also activates effector-triggered immunity in resistant backgrounds. Although HopZ1a has been shown to interfere with early defense signaling at the PM, no dedicated PM-associated HopZ1a target protein has been identified until now. Here, we show that HopZ1a interacts with the PM-associated remorin protein NbREM4 from Nicotiana benthamiana in several independent assays. NbREM4 relocalizes to membrane nanodomains after treatment with the bacterial elicitor flg22 and transient overexpression of NbREM4 in N. benthamiana induces the expression of a subset of defense-related genes. We can further show that NbREM4 interacts with the immune-related receptor-like cytoplasmic kinase avrPphB-susceptible 1 (PBS1) and is phosphorylated by PBS1 on several residues in vitro. Thus, we conclude that NbREM4 is associated with early defense signaling at the PM. The possible relevance of the HopZ1a-NbREM4 interaction for HopZ1a virulence and avirulence functions is discussed.
KW  - bacterial pathogenesis
KW  - defense signaling pathways
KW  - effectors
KW  - elicitors
KW  - HopZ1a
KW  - MAMPs
KW  - PAMPs
KW  - PBS1
KW  - Pseudomonas syringae
KW  - remorin
KW  - type-3 secretion
Y1  - 2019
U6  - https://doi.org/10.1094/MPMI-04-19-0105-R
SN  - 0894-0282
SN  - 1943-7706
VL  - 32
IS  - 9
SP  - 1229
EP  - 1242
PB  - Amer phytopathological  SOC
CY  - ST Paul
ER  - 
TY  - JOUR
A1  - Albrecht, Anna Helena
T1  - Schweigen ist Silber, Reden ist Gold: Ausgleichs- und Rügemöglichkeiten bei belehrungsfehlerbedingtem Unterlassen einer günstigen Beschuldigteneinlassung
JF  - Zeitschrift für die gesamte Strafrechtswissenschaft
Y1  - 2019
U6  - https://doi.org/10.1515/zstw-2019-0004
SN  - 0084-5310
SN  - 1612-703X
VL  - 131
IS  - 1
SP  - 97
EP  - 130
PB  - De Gruyter
ER  - 
TY  - JOUR
A1  - Aldrup, Marit
T1  - Well let me put it uhm the other way around maybe’
BT  - Managing students’ trouble displays in the CLIL classroom
JF  - Classroom discourse
N2  - This study is concerned with repair practices that a teacher and students employ to restore intersubjectivity when faced with interactional problems in a Content and Language Integrated Learning (CLIL) classroom. Adopting a conversation analytic (CA) approach, it examines the interactional treatment of students’ verbal and embodied trouble displays in a video-recorded, teacher-fronted geography lesson held in English at a German high school. At the same time, it explores to what extent the repair practices employed are fitted to this specific interactional context. The analysis shows that students’ verbal trouble displays often result in extensive repair sequences, whereas students’ embodied trouble displays are usually met with teacher self-repair in the transition space. In this way, the latter are resolved much earlier and more quickly. The study further reveals practices like reformulation and translation to be especially useful for repairing interactional problems in classrooms in which a foreign language is used as the medium of instruction. The findings may be of interest for prospective as well as practicing teachers in that they provide relevant insights into how interactional trouble can be successfully managed in (CLIL) classroom interaction.
KW  - Trouble displays
KW  - repair
KW  - embodiment
KW  - classroom interaction
KW  - conversation analysis
Y1  - 2019
U6  - https://doi.org/10.1080/19463014.2019.1567360
SN  - 1946-3014
SN  - 1946-3022
VL  - 10
IS  - 1
SP  - 46
EP  - 70
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Alexiadou, Artemis
T1  - A form-function mismatch?
BT  - The case of Greek deponents
JF  - Of trees and birds. A Festschrift for Gisbert Fanselow
KW  - Festschrift
KW  - Informationsstruktur
KW  - Linguistik
KW  - Morphologie
KW  - Syntax
KW  - festschrift
KW  - information structure
KW  - linguistics
KW  - morphology
KW  - syntax
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-432235
SN  - 978-3-86956-457-9
SP  - 107
EP  - 117
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Alker, Wiebke
A1  - Schwerdtle, Tanja
A1  - Schomburg, Lutz
A1  - Haase, Hajo
T1  - A Zinpyr-1-based Fluorimetric Microassay for Free Zinc in Human Serum
JF  - International journal of molecular sciences
N2  - Zinc is an essential trace element, making it crucial to have a reliable biomarker for evaluating an individual’s zinc status. The total serum zinc concentration, which is presently the most commonly used biomarker, is not ideal for this purpose, but a superior alternative is still missing. The free zinc concentration, which describes the fraction of zinc that is only loosely bound and easily exchangeable, has been proposed for this purpose, as it reflects the highly bioavailable part of serum zinc. This report presents a fluorescence-based method for determining the free zinc concentration in human serum samples, using the fluorescent probe Zinpyr-1. The assay has been applied on 154 commercially obtained human serum samples. Measured free zinc concentrations ranged from 0.09 to 0.42 nM with a mean of 0.22 ± 0.05 nM. It did not correlate with age or the total serum concentrations of zinc, manganese, iron or selenium. A negative correlation between the concentration of free zinc and total copper has been seen for sera from females. In addition, the free zinc concentration in sera from females (0.21 ± 0.05 nM) was significantly lower than in males (0.23 ± 0.06 nM). The assay uses a sample volume of less than 10 µL, is rapid and cost-effective and allows us to address questions regarding factors influencing the free serum zinc concentration, its connection with the body’s zinc status, and its suitability as a future biomarker for an individual’s zinc status.
KW  - zinc
KW  - free zinc
KW  - serum
KW  - biomarker
KW  - fluorescent probe
KW  - Zinypr-1
Y1  - 2019
U6  - https://doi.org/10.3390/ijms20164006
SN  - 1661-6596
SN  - 1422-0067
VL  - 20
IS  - 16
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Alleweldt, Ralf
T1  - Der Interlaken-Prozess, die Erklärung von Kopenhagen und die Verwirklichung der Menschenrechte in Europa
JF  - MenschenRechtsMagazin : MRM ; Informationen, Meinungen, Analysen
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-474180
SN  - 1434-2820
VL  - 24
IS  - 1/2
SP  - 53
EP  - 66
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Allroggen, Niklas Robin
A1  - Booth, Adam D.
A1  - Baker, Sandra E.
A1  - Ellwood, Stephen A.
A1  - Tronicke, Jens
T1  - High-resolution imaging and monitoring of animal tunnels using 3D ground-penetrating radar
JF  - Near surface geophysics
N2  - Ground-penetrating radar is widely used to provide highly resolved images of subsurface sedimentary structures, with implications for processes active in the vadose zone. Frequently overlooked among these structures are tunnels excavated by fossorial animals (e.g., moles). We present two repeated ground-penetrating radar surveys performed a year apart in 2016 and 2017. Careful three-dimensional data processing reveals, in each data set, a pattern of elongated structures that are interpreted as a subsurface mole tunnel network. Our data demonstrate the ability of three-dimensional ground-penetrating radar imaging to non-invasively delineate the small animal tunnels (similar to 5 cm diameter) at a higher spatial and geolocation resolution than has previously been achieved. In turn, this makes repeated surveys and, therefore, long-term monitoring possible. Our results offer valuable insight into the understanding of the near-surface and showcase a potential new application for a geophysical method as well as a non-invasive method of ecological surveying.
KW  - Ground-penetrating radar
KW  - Shallow subsurface
KW  - Environmental
Y1  - 2019
U6  - https://doi.org/10.1002/nsg.12039
SN  - 1569-4445
SN  - 1873-0604
VL  - 17
IS  - 3
SP  - 291
EP  - 298
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Aloni, Sapir Shekef
A1  - Perovic, Milena
A1  - Weitman, Michal
A1  - Cohen, Reut
A1  - Oschatz, Martin
A1  - Mastai, Yitzhak
T1  - Amino acid-based ionic liquids as precursors for the synthesis of chiral nanoporous carbons
JF  - Nanoscale Advances
N2  - The synthesis of chiral nanoporous carbons based on chiral ionic liquids (CILs) of amino acids as precursors is described. Such unique precursors for the carbonization of CILs yield chiral carbonaceous materials with high surface area (approximate to 620 m(2) g(-1)). The enantioselectivities of the porous carbons are examined by advanced techniques such as selective adsorption of enantiomers using cyclic voltammetry, isothermal titration calorimetry, and mass spectrometry. These techniques demonstrate the chiral nature and high enantioselectivity of the chiral carbon materials. Overall, we believe that the novel approach presented here can contribute significantly to the development of new chiral carbon materials that will find important applications in chiral chemistry, such as in chiral catalysis and separation and in chiral sensors. From a scientific point of view, the approach and results reported here can significantly deepen our understanding of chirality at the nanoscale and of the structure and nature of chiral nonporous materials and surfaces.
Y1  - 2019
U6  - https://doi.org/10.1039/c9na00520j
SN  - 2516-0230
VL  - 1
IS  - 12
SP  - 4981
EP  - 4988
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Alrefai, Anas
A1  - Mondal, Suvendu Sekhar
A1  - Wruck, Alexander
A1  - Kelling, Alexandra
A1  - Schilde, Uwe
A1  - Brandt, Philipp
A1  - Janiak, Christoph
A1  - Schoenfeld, Sophie
A1  - Weber, Birgit
A1  - Rybakowski, Lawrence
A1  - Herrman, Carmen
A1  - Brennenstuhl, Katlen
A1  - Eidner, Sascha
A1  - Kumke, Michael Uwe
A1  - Behrens, Karsten
A1  - Günter, Christina
A1  - Müller, Holger
A1  - Holdt, Hans-Jürgen
T1  - Hydrogen-bonded supramolecular metal-imidazolate frameworks: gas sorption, magnetic and UV/Vis spectroscopic properties
JF  - Journal of Inclusion Phenomena and Macrocyclic Chemistry
N2  - By varying reaction parameters for the syntheses of the hydrogen-bonded metal-imidazolate frameworks (HIF) HIF-1 and HIF-2 (featuring 14 Zn and 14 Co atoms, respectively) to increase their yields and crystallinity, we found that HIF-1 is generated in two different frameworks, named as HIF-1a and HIF-1b. HIF-1b is isostructural to HIF-2. We determined the gas sorption and magnetic properties of HIF-2. In comparison to HIF-1a (Brunauer-Emmett-Teller (BET) surface area of 471m(2) g(-1)), HIF-2 possesses overall very low gas sorption uptake capacities [BET(CO2) surface area=85m(2) g(-1)]. Variable temperature magnetic susceptibility measurement of HIF-2 showed antiferromagnetic exchange interactions between the cobalt(II) high-spin centres at lower temperature. Theoretical analysis by density functional theory confirmed this finding. The UV/Vis-reflection spectra of HIF-1 (mixture of HIF-1a and b), HIF-2 and HIF-3 (with 14 Cd atoms) were measured and showed a characteristic absorption band centered at 340nm, which was indicative for differences in the imidazolate framework.
KW  - Gas-sorption
KW  - Ligand design
KW  - Magnetic properties
KW  - Supramolecular chemistry
KW  - Solvothermal synthesis
Y1  - 2019
U6  - https://doi.org/10.1007/s10847-019-00926-6
SN  - 1388-3127
SN  - 1573-1111
VL  - 94
IS  - 3-4
SP  - 155
EP  - 165
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Altieri, Riccardo
T1  - Luxemburg oder Lenin?
BT  - die unterschiedlichen Positionen von Rosi Wolfstein und Paul Fröhlich zur Revolution in Russland
JF  - Die Wahrnehmung der Russischen Revolutionen 1917 : Zwischen utopischen Träumen und erschütterter Ablehnung (2019)
Y1  - 2019
SN  - 978-3-86331-469-9
SP  - 31
EP  - 56
PB  - Metropol
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Altieri, Riccardo
T1  - Paul Frölichs Theorie zur Vergleichbarkeit von Revolutionen-Rekonstruktion eines Modellversuchs
JF  - Revolution : Beiträge zu einem historischen Phänomen der globalen Moderne
Y1  - 2019
SN  - 978-3-96138-158-6
SP  - 99
EP  - 118
PB  - wvb  Wissenschaftlicher Verlag
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Altieri, Riccardo
A1  - Jacob, Frank
T1  - Vorwort
JF  - Revolution : Beiträge zu einem historischen Phänomen der globalen Moderne
Y1  - 2019
SN  - 978-3-96138-158-6
SP  - 7
EP  - 10
PB  - wvb  Wissenschaftlicher Verlag
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Altintas, Zeynep
A1  - Takiden, Aref
A1  - Utesch, Tillmann
A1  - Mroginski, Maria A.
A1  - Schmid, Bianca
A1  - Scheller, Frieder W.
A1  - Süssmuth, Roderich D.
T1  - Integrated approaches toward high-affinity artificial protein binders obtained via computationally simulated epitopes for protein recognition
JF  - Advanced functional materials
N2  - Widely used diagnostic tools make use of antibodies recognizing targeted molecules, but additional techniques are required in order to alleviate the disadvantages of antibodies. Herein, molecular dynamic calculations are performed for the design of high affinity artificial protein binding surfaces for the recognition of neuron specific enolase (NSE), a known cancer biomarker. Computational simulations are employed to identify particularly stabile secondary structure elements. These epitopes are used for the subsequent molecular imprinting, where surface imprinting approach is applied. The molecular imprints generated with the calculated epitopes of greater stability (Cys-Ep1) show better binding properties than those of lower stability (Cys-Ep5). The average binding strength of imprints created with stabile epitopes is found to be around twofold and fourfold higher for the NSE derived peptide and NSE protein, respectively. The recognition of NSE is investigated in a wide concentration range, where high sensitivity (limit of detection (LOD) = 0.5 ng mL(-1)) and affinity (dissociation constant (K-d) = 5.3 x 10(-11)m) are achieved using Cys-Ep1 imprints reflecting the stable structure of the template molecules. This integrated approach employing stability calculations for the identification of stabile epitopes is expected to have a major impact on the future development of high affinity protein capturing binders.
KW  - artificial protein binders
KW  - cancer markers
KW  - computationally simulated epitopes
KW  - molecular imprinting
KW  - protein recognition
Y1  - 2019
U6  - https://doi.org/10.1002/adfm.201807332
SN  - 1616-301X
SN  - 1616-3028
VL  - 29
IS  - 15
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Alxatib, Sam
A1  - Sauerland, Ulrich
T1  - Vagueness
JF  - The Oxford Handbook of Experimental Semantics and Pragmatics
N2  - Though vague phenomena have been studied extensively for many decades, it is only in recent years that researchers sought the support of quantitative data. This chapter highlights and discusses the insights that experimental methods brought to the study of vagueness. One area focused on are ‘borderline contradictions’, that is, sentences like ‘She is neither tall nor not tall’ that are contradictory when analysed in classical logic, but are actually acceptable as descriptions of borderline cases. The flourishing of theories and experimental studies that borderline contradictions have led to are examined closely. Beyond this illustrative case, an overview of recent studies that concern the classification of types of vagueness, the use of numbers, rounding, number modification, and the general pragmatic status of vagueness is provided.
KW  - vagueness
KW  - gradability
KW  - categories
KW  - borderline cases
KW  - contradiction
KW  - valency
KW  - imprecision
KW  - hysteresis
KW  - pragmatics
KW  - semantics
Y1  - 2019
U6  - https://doi.org/10.1093/oxfordhb/9780198791768.013.24
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Amaechi, Mary Chimaobi
A1  - Georgi, Doreen
T1  - Quirks of subject (non-)extraction in Igbo
JF  - Glossa : a journal of general linguistics
N2  - In this paper we present new data on a subject/non-subject extraction asymmetry in Igbo constituent questions. We provide evidence that the superficially morphological phenomenon reflects a deeper syntactic asymmetry: Unlike wh-non-subjects, wh-subjects cannot undergo local (A) over bar -movement to the left periphery (SpecFoc); rather, they have to stay in their canonical position SpecT. The same constraint also leads to the that-trace effect (absence of the complementizer) in the embedded clause of long subject wh-movement. We argue that what is responsible for the special status of wh-subjects is their high structural position. We provide an optimality-theoretic analysis of the asymmetry that is based on anti-locality: Local subject (A) over bar -movement is excluded because it is too short. Moreover, we address the nature of apparent wh-in-situ in Igbo.
KW  - extraction asymmetries
KW  - wh-movement
KW  - wh-in-situ
KW  - focus marking
KW  - that-trace effect
Y1  - 2019
U6  - https://doi.org/10.5334/gjgl.607
SN  - 2397-1835
VL  - 4
IS  - 1
PB  - Ubiquity Press
CY  - London
ER  - 
TY  - JOUR
A1  - Andrés-Delgado, Laura
A1  - Ernst, Alexander
A1  - Galardi-Castilla, María
A1  - Bazaga, David
A1  - Peralta, Marina
A1  - Münch, Juliane
A1  - Gonzalez-Rosa, Juan M.
A1  - Marques, Inês
A1  - Tessadori, Federico
A1  - de la Pompa, José Luis
A1  - Vermot, Julien
A1  - Mercader, Nadia
T1  - Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells
JF  - Development : Company of Biologists
N2  - The epicardium, the outer mesothelial layer enclosing the myocardium, plays key roles in heart development and regeneration. During embryogenesis, the epicardium arises from the proepicardium (PE), a cell cluster that appears in the dorsal pericardium (DP) close to the venous pole of the heart. Little is known about how the PE emerges from the pericardial mesothelium. Using a zebrafish model and a combination of genetic tools, pharmacological agents and quantitative in vivo imaging, we reveal that a coordinated collective movement of DP cells drives PE formation. We found that Bmp signaling and the actomyosin cytoskeleton promote constriction of the DP, which enables PE cells to extrude apically. We provide evidence that cell extrusion, which has been described in the elimination of unfit cells from epithelia and the emergence of hematopoietic stem cells, is also a mechanism for PE cells to exit an organized mesothelium and fulfil their developmental fate to form a new tissue layer, the epicardium.
KW  - Actomyosin
KW  - Bmp
KW  - Cell extrusion
KW  - Proepicardium
KW  - Zebrafish
KW  - Heart development
Y1  - 2019
U6  - https://doi.org/10.1242/dev.174961
SN  - 0950-1991
SN  - 1477-9129
VL  - 146
IS  - 13
PB  - The Company of Biologists Ltd
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Angeleska, Angela
A1  - Nikoloski, Zoran
T1  - Coherent network partitions
JF  - Discrete applied mathematics
N2  - Graph clustering is widely applied in the analysis of cellular networks reconstructed from large-scale data or obtained from experimental evidence. Here we introduce a new type of graph clustering based on the concept of coherent partition. A coherent partition of a graph G is a partition of the vertices of G that yields only disconnected subgraphs in the complement of G. The coherence number of G is then the size of the smallest edge cut inducing a coherent partition. A coherent partition of G is optimal if the size of the inducing edge cut is the coherence number of G. Given a graph G, we study coherent partitions and the coherence number in connection to (bi)clique partitions and the (bi)clique cover number. We show that the problem of finding the coherence number is NP-hard, but is of polynomial time complexity for trees. We also discuss the relation between coherent partitions and prominent graph clustering quality measures.
KW  - Graph partitions
KW  - Network clustering
KW  - Coherence number
KW  - Coherent partition
Y1  - 2019
U6  - https://doi.org/10.1016/j.dam.2019.02.048
SN  - 0166-218X
SN  - 1872-6771
VL  - 266
SP  - 283
EP  - 290
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Angelopoulos, Michael
A1  - Westermann, Sebastian
A1  - Overduin, Pier Paul
A1  - Faguet, Alexey
A1  - Olenchenko, Vladimir
A1  - Grosse, Guido
A1  - Grigoriev, Mikhail N.
T1  - Heat and salt flow in subsea permafrost modeled with CryoGRID2
JF  - Journal of geophysical research : Earth surface
N2  - Thawing of subsea permafrost can impact offshore infrastructure, affect coastal erosion, and release permafrost organic matter. Thawing is usually modeled as the result of heat transfer, although salt diffusion may play an important role in marine settings. To better quantify nearshore subsea permafrost thawing, we applied the CryoGRID2 heat diffusion model and coupled it to a salt diffusion model. We simulated coastline retreat and subsea permafrost evolution as it develops through successive stages of a thawing sequence at the Bykovsky Peninsula, Siberia. Sensitivity analyses for seawater salinity were performed to compare the results for the Bykovsky Peninsula with those of typical Arctic seawater. For the Bykovsky Peninsula, the modeled ice-bearing permafrost table (IBPT) for ice-rich sand and an erosion rate of 0.25m/year was 16.7 m below the seabed 350m offshore. The model outputs were compared to the IBPT depth estimated from coastline retreat and electrical resistivity surveys perpendicular to and crossing the shoreline of the Bykovsky Peninsula. The interpreted geoelectric data suggest that the IBPT dipped to 15-20m below the seabed at 350m offshore. Both results suggest that cold saline water forms beneath grounded ice and floating sea ice in shallow water, causing cryotic benthic temperatures. The freezing point depression produced by salt diffusion can delay or prevent ice formation in the sediment and enhance the IBPT degradation rate. Therefore, salt diffusion may facilitate the release of greenhouse gasses to the atmosphere and considerably affect the design of offshore and coastal infrastructure in subsea permafrost areas.
KW  - subsea permafrost
KW  - salt diffusion
KW  - CryoGRID
KW  - Lena Delta
KW  - Bykovsky Peninsula
KW  - electrical resistivity
Y1  - 2019
U6  - https://doi.org/10.1029/2018JF004823
SN  - 2169-9003
SN  - 2169-9011
VL  - 124
IS  - 4
SP  - 920
EP  - 937
PB  - American Geophysical Union
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Apelojg, Benjamin
ED  - Kirchner, Vera
ED  - Wüste, Andreas
T1  - Forschendes Lernen im Praxissemester
BT  - Herausforderungen in der Unterrichtspraxis mit wissenschaftlichen Methoden begegnen
JF  - Unterricht Wirtschaft & Politik
N2  - Das Praxissemester als praxisbezogenes Studienelement zur Förderung von Professions- und Reflexionskompetenzen ist in immer mehr Bundesländern integraler Bestandteil der Lehramtsausbildung. Eine zentrale Herausforderung ist hierbei die gelingende Integration von universitärer Theorie und schulischer Praxis. Das Forschende Lernen kann hierzu einen wichtigen Beitrag leisten, indem Herausforderungen aus der unterrichtlichen Praxis einem forschenden Blick unterzogen und mit wissenschaftlichen Methoden bearbeitet werden. Dies soll nicht zuletzt die Reflexionskompetenz der angehenden Lehrerinnen und Lehrer fördern.
KW  - Praxissemester
KW  - Forschendes Lernen
KW  - Prozessorientierte Didaktik
Y1  - 2019
UR  - https://www.friedrich-verlag.de/wirtschaft-politik/beruf-orientierung/forschendes-lernen-im-praxissemester-5020
SN  - 2751-1243
SN  - 2191-6624
IS  - 2
SP  - 41
EP  - 44
PB  - Friedrich Verlag GmbH
CY  - Hannover
ER  - 
TY  - JOUR
A1  - Appiah-Dwomoh, Edem Korkor
A1  - Müller, Steffen
A1  - Mayer, Frank
T1  - Is there an association between variables of static and dynamic postural control in adolescent athletes with back pain?
T1  - Gibt es einen Zusammenhang zwischen Variablen der statischen und dynamischen posturalen Kontrolle bei Nachwuchsathleten mit Rückenschmerzen?
JF  - German Journal of Exercise and Sport Research
N2  - An association between static and dynamic postural control exists in adults with back pain. We aimed to determine whether this association also exists in adolescent athletes with the same condition. In all, 128 athletes with and without back pain performed three measurements of 15s of static (one-legged stance) and dynamic (star excursion balance test) postural control tests. All subjects and amatched subgroup of athletes with and without back pain were analyzed. The smallest center of pressure mediolateral and anterior-posterior displacements (mm) and normalized highest reach distance were the outcome measures. No association was found between variables of the static and dynamic tests for all subjects and the matched group with and without back pain. The control of static and dynamic posture in adolescent athletes with and without back pain might not be related.
N2  - Bei Erwachsenen mit Rückenschmerzen besteht ein Zusammenhang zwischen statischer und dynamischer posturaler Kontrolle. Ziel der Studie war es zu untersuchen, ob dieser Zusammenhang auch bei Nachwuchsathleten mit Rückenschmerzen nachweisbar ist. Insgesamt 128 Nachwuchsathleten mit oder ohne Rückenschmerzen führten je 3 Messungen à 15 s eines statischen (einbeiniger Standtest) bzw. dynamischen („star excursion balance test“ [SEBT]) posturalen Kontrolltests durch. In die Auswertung wurden sowohl die gesamte Stichprobe als auch eine gematchte Untergruppe einbezogen. Zielparameter waren der kleinste mediolaterale und anterior-posteriore Schwankungsweg im Einbeinstand (mm) und die normierte maximal erreichte Distanz im SEBT. Es wurden keine Zusammenhänge zwischen Variablen der statischen und dynamischen Tests für alle Studienteilnehmer und der gematchten Untergruppe mit und ohne Rückenschmerzen festgestellt. Obwohl ein Zusammenhang zwischen statischer und dynamischer posturaler Kontrolle angenommen wird, konnte dieser bei Nachwuchsathleten mit oder ohne Rückenschmerzen nicht nachgewiesen werden.
KW  - Postural control
KW  - Adolescent athletes
KW  - Back pain
KW  - One-legged stance
KW  - Star excursion balance test
KW  - Posturale Kontrolle
KW  - Nachwuchsathleten
KW  - Rückenschmerzen
KW  - Einbeiniger Standtest
Y1  - 2019
U6  - https://doi.org/10.1007/s12662-019-00573-6
SN  - 2509-3142
SN  - 2509-3150
VL  - 49
IS  - 2
SP  - 150
EP  - 155
PB  - Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Araya Vargas, Jaime Andrés
A1  - Meqbel, Naser M.
A1  - Ritter, Oliver
A1  - Brasse, H.
A1  - Weckmann, Ute
A1  - Yanez, Gonzalo
A1  - Godoy, B.
T1  - Fluid Distribution in the Central Andes Subduction Zone Imaged With Magnetotellurics
JF  - Journal of geophysical research : Solid earth
N2  - We present a model of the electrical resistivity structure of the lithosphere in the Central Andes between 20 degrees and 24 degrees S from 3-D inversion of 56 long-period magnetotelluric sites. Our model shows a complex resistivity structure with significant variability parallel and perpendicular to the trench direction. The continental forearc is characterized mainly by high electrical resistivity (>1,000m), suggesting overall low volumes of fluids. However, low resistivity zones (LRZs, <5m) were found in the continental forearc below areas where major trench-parallel faults systems intersect NW-SE transverse faults. Forearc LRZs indicate circulation and accumulation of fluids in highly permeable fault zones. The continental crust along the arc shows three distinctive resistivity domains, which coincide with segmentation in the distribution of volcanoes. The northern domain (20 degrees-20.5 degrees S) is characterized by resistivities >1,000m and the absence of active volcanism, suggesting the presence of a low-permeability block in the continental crust. The central domain (20.5 degrees-23 degrees S) exhibits a number of LRZs at varying depths, indicating different levels of a magmatic plumbing system. The southern domain (23 degrees-24 degrees S) is characterized by resistivities >1,000m, suggesting the absence of large magma reservoirs below the volcanic chain at crustal depths. Magma reservoirs located below the base of the crust or in the backarc may fed active volcanism in the southern domain. In the subcontinental mantle, the model exhibits LRZs in the forearc mantle wedge and above clusters of intermediate-depth seismicity, likely related to fluids produced by serpentinization of the mantle and eclogitization of the slab, respectively.
KW  - Subduction Zone
KW  - Central Andes
KW  - Magnetotellurics
KW  - Seismotectonic segmentation
KW  - Fluid processes
Y1  - 2019
U6  - https://doi.org/10.1029/2018JB016933
SN  - 2169-9313
SN  - 2169-9356
VL  - 124
IS  - 4
SP  - 4017
EP  - 4034
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Archer, A.
A1  - Benbow, Wystan
A1  - Bird, Ralph
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Buckley, J. H.
A1  - Chromey, A. J.
A1  - Cui, Wei
A1  - Falcone, A.
A1  - Feng, Qi
A1  - Finley, J. P.
A1  - Fortson, Lucy
A1  - Furniss, Amy
A1  - Gent, A.
A1  - Gueta, O.
A1  - Hanna, David
A1  - Hassan, T.
A1  - Hervet, Olivier
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Johnson, Caitlin A.
A1  - Kaaret, Philip
A1  - Kar, P.
A1  - Kelley-Hoskins, N.
A1  - Kertzman, M.
A1  - Kieda, David
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - McCann, A.
A1  - Moriarty, P.
A1  - Mukherjee, Reshmi
A1  - Ong, R. A.
A1  - Otte, Adam Nepomuk
A1  - Pandel, D.
A1  - Park, N.
A1  - Petrashyk, A.
A1  - Pohl, Martin
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Richards, Gregory T.
A1  - Roache, E.
A1  - Sadeh, I
A1  - Santander, Marcos
A1  - Scott, S. S.
A1  - Sembroski, G. H.
A1  - Shahinyan, Karlen
A1  - Sushch, Iurii
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Wells, R. M.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Williamson, T. J.
A1  - Zitzer, B.
T1  - A Search for Pulsed Very High-energy Gamma-Rays from 13 Young Pulsars in Archival VERITAS Data
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We conduct a search for periodic emission in the very high-energy (VHE) gamma-ray band (E > 100 GeV) from a total of 13 pulsars in an archival VERITAS data set with a total exposure of over 450 hr. The set of pulsars includes many of the brightest young gamma-ray pulsars visible in the Northern Hemisphere. The data analysis resulted in nondetections of pulsed VHE gamma-rays from each pulsar. Upper limits on a potential VHE gamma-ray flux are derived at the 95% confidence level above three energy thresholds using two methods. These are the first such searches for pulsed VHE emission from each of the pulsars, and the obtained limits constrain a possible flux component manifesting at VHEs as is seen for the Crab pulsar.
KW  - gamma rays: general
KW  - pulsars: general
KW  - stars: neutron
Y1  - 2019
U6  - https://doi.org/10.3847/1538-4357/ab14f4
SN  - 0004-637X
SN  - 1538-4357
VL  - 876
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Arnold, Taylor
A1  - Ballier, Nicolas
A1  - Lisson, Paula
A1  - Tilton, Lauren
T1  - Beyond lexical frequencies: using R for text analysis in the digital humanities
JF  - Language resources and evaluation
N2  - This paper presents a combination of R packages-user contributed toolkits written in a common core programming language-to facilitate the humanistic investigation of digitised, text-based corpora.Our survey of text analysis packages includes those of our own creation (cleanNLP and fasttextM) as well as packages built by other research groups (stringi, readtext, hyphenatr, quanteda, and hunspell). By operating on generic object types, these packages unite research innovations in corpus linguistics, natural language processing, machine learning, statistics, and digital humanities. We begin by extrapolating on the theoretical benefits of R as an elaborate gluing language for bringing together several areas of expertise and compare it to linguistic concordancers and other tool-based approaches to text analysis in the digital humanities. We then showcase the practical benefits of an ecosystem by illustrating how R packages have been integrated into a digital humanities project. Throughout, the focus is on moving beyond the bag-of-words, lexical frequency model by incorporating linguistically-driven analyses in research.
KW  - Digital humanities
KW  - Text mining
KW  - R
KW  - Text interoperability
Y1  - 2019
U6  - https://doi.org/10.1007/s10579-019-09456-6
SN  - 1574-020X
SN  - 1574-0218
VL  - 53
IS  - 4
SP  - 707
EP  - 733
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Asche, Matthias
T1  - The Augsburg Religious Peace of 1555
BT  - Consequences and Problems for the Territories and Cities in the Northern Part of the Old Reich
JF  - Historisches Jahrbuch
Y1  - 2019
SN  - 0018-2621
VL  - 139
SP  - 31
EP  - 66
PB  - Herder
CY  - Freiburg Breisgau
ER  - 
TY  - JOUR
A1  - Asche, Matthias
ED  - Chihaia, Matei
ED  - Eckert, Georg
T1  - Dynastietreue und Landesidentität
BT  - zur Jubiläumskultur an südwestdeutschen Universitäten seit dem 19. Jahrhundert
JF  - Kolossale Miniaturen : Festschrift für Gerrit Walther
Y1  - 2019
SN  - 978-3-402-13411-5
SP  - 89
EP  - 97
PB  - Aschendorff
CY  - Münster
ER  - 
TY  - JOUR
A1  - Asche, Matthias
T1  - Wie tolerant waren die Hohenzollern?
BT  - Eine kritische Sicht auf das sogenannte „Toleranzedikt“ von Potsdam
JF  - Die Hugenotten in Berlin (= Berliner Geschichte. Zeitschrift für Geschichte und Kultur)
Y1  - 2019
SN  - 978-3-96201-024-9
VL  - 2019
SP  - 34
EP  - 41
PB  - Elsengold
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Asche, Matthias
ED  - Braun, Karl-Heinz
ED  - Brechenmacher, Thomas
ED  - Damberg, Wilhelm
ED  - Fößel, Amalie
ED  - Kampmann, Christoph
ED  - Körntgen, Ludger
ED  - Löffler, Bernhard
ED  - Schindling, Anton
T1  - Der Augsburger Religionsfrieden von 1555
BT  - Folgen und Probleme für die Territorien und Städte im Norden des Alten Reiches
JF  - Historisches Jahrbuch
Y1  - 2019
SN  - 978-3-451-38586-5
IS  - 139
SP  - 31
EP  - 66
PB  - Herder
CY  - Freiburg im Breisgau
ER  - 
TY  - JOUR
A1  - Aseev, Nikita
A1  - Shprits, Yuri Y.
T1  - Reanalysis of ring current electron phase space densities using van allen probe observations, convection model, and log‐normal kalman filter
JF  - Space weather : the international journal of research and applications
N2  - Models of ring current electron dynamics unavoidably contain uncertainties in boundary conditions, electric and magnetic fields, electron scattering rates, and plasmapause location. Model errors can accumulate with time and result in significant deviations of model predictions from observations. Data assimilation offers useful tools which can combine physics-based models and measurements to improve model predictions. In this study, we systematically analyze performance of the Kalman filter applied to a log-transformed convection model of ring current electrons and Van Allen Probe data. We consider long-term dynamics of mu = 2.3 MeV/G and K = 0.3 G(1/2) R-E electrons from 1 February 2013 to 16 June 2013. By using synthetic data, we show that the Kalman filter is capable of correcting errors in model predictions associated with uncertainties in electron lifetimes, boundary conditions, and convection electric fields. We demonstrate that reanalysis retains features which cannot be fully reproduced by the convection model such as storm-time earthward propagation of the electrons down to 2.5 R-E. The Kalman filter can adjust model predictions to satellite measurements even in regions where data are not available. We show that the Kalman filter can adjust model predictions in accordance with observations for mu = 0.1, 2.3, and 9.9 MeV/G and constant K = 0.3 G(1/2) R-E electrons. The results of this study demonstrate that data assimilation can improve performance of ring current models, better quantify model uncertainties, and help deeper understand the physics of the ring current particles.
Y1  - 2019
U6  - https://doi.org/10.1029/2018SW002110
SN  - 1542-7390
VL  - 17
IS  - 4
SP  - 619
EP  - 638
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Aseev, Nikita
A1  - Shprits, Yuri Y.
A1  - Wang, Dedong
A1  - Wygant, John
A1  - Drozdov, Alexander
A1  - Kellerman, Adam C.
A1  - Reeves, Geoffrey D.
T1  - Transport and loss of ring current electrons inside geosynchronous orbit during the 17 March 2013 storm
JF  - Journal of geophysical research : Space physics
N2  - Ring current electrons (1–100 keV) have received significant attention in recent decades, but many questions regarding their major transport and loss mechanisms remain open. In this study, we use the four‐dimensional Versatile Electron Radiation Belt code to model the enhancement of phase space density that occurred during the 17 March 2013 storm. Our model includes global convection, radial diffusion, and scattering into the Earth's atmosphere driven by whistler‐mode hiss and chorus waves. We study the sensitivity of the model to the boundary conditions, global electric field, the electric field associated with subauroral polarization streams, electron loss rates, and radial diffusion coefficients. The results of the code are almost insensitive to the model parameters above 4.5 RERE, which indicates that the general dynamics of the electrons between 4.5 RE and the geostationary orbit can be explained by global convection. We found that the major discrepancies between the model and data can stem from the inaccurate electric field model and uncertainties in lifetimes. We show that additional mechanisms that are responsible for radial transport are required to explain the dynamics of ≥40‐keV electrons, and the inclusion of the radial diffusion rates that are typically assumed in radiation belt studies leads to a better agreement with the data. The overall effect of subauroral polarization streams on the electron phase space density profiles seems to be smaller than the uncertainties in other input parameters. This study is an initial step toward understanding the dynamics of these particles inside the geostationary orbit.
KW  - ring current electrons
KW  - magnetospheric convection
KW  - ensemble modeling
KW  - inner magnetosphere
KW  - electron transport
KW  - wave-particle interactions
Y1  - 2019
U6  - https://doi.org/10.1029/2018JA026031
SN  - 2169-9380
SN  - 2169-9402
VL  - 124
IS  - 2
SP  - 915
EP  - 933
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Asgarimehr, Milad
A1  - Wickert, Jens
A1  - Reich, Sebastian
T1  - Evaluating impact of rain attenuation on space-borne GNSS reflectometry wind speeds
JF  - Remote Sensing
N2  - The novel space-borne Global Navigation Satellite System Reflectometry (GNSS-R) technique has recently shown promise in monitoring the ocean state and surface wind speed with high spatial coverage and unprecedented sampling rate. The L-band signals of GNSS are structurally able to provide a higher quality of observations from areas covered by dense clouds and under intense precipitation, compared to those signals at higher frequencies from conventional ocean scatterometers. As a result, studying the inner core of cyclones and improvement of severe weather forecasting and cyclone tracking have turned into the main objectives of GNSS-R satellite missions such as Cyclone Global Navigation Satellite System (CYGNSS). Nevertheless, the rain attenuation impact on GNSS-R wind speed products is not yet well documented. Evaluating the rain attenuation effects on this technique is significant since a small change in the GNSS-R can potentially cause a considerable bias in the resultant wind products at intense wind speeds. Based on both empirical evidence and theory, wind speed is inversely proportional to derived bistatic radar cross section with a natural logarithmic relation, which introduces high condition numbers (similar to ill-posed conditions) at the inversions to high wind speeds. This paper presents an evaluation of the rain signal attenuation impact on the bistatic radar cross section and the derived wind speed. This study is conducted simulating GNSS-R delay-Doppler maps at different rain rates and reflection geometries, considering that an empirical data analysis at extreme wind intensities and rain rates is impossible due to the insufficient number of observations from these severe conditions. Finally, the study demonstrates that at a wind speed of 30 m/s and incidence angle of 30 degrees, rain at rates of 10, 15, and 20 mm/h might cause overestimation as large as approximate to 0.65 m/s (2%), 1.00 m/s (3%), and 1.3 m/s (4%), respectively, which are still smaller than the CYGNSS required uncertainty threshold. The simulations are conducted in a pessimistic condition (severe continuous rainfall below the freezing height and over the entire glistening zone) and the bias is expected to be smaller in size in real environments.
KW  - GNSS Reflectometry
KW  - wind speed
KW  - rain effect
KW  - rain attenuation
KW  - DDM simulation
Y1  - 2019
U6  - https://doi.org/10.3390/rs11091048
SN  - 2072-4292
VL  - 11
IS  - 9
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Ashton, Michelle P.
A1  - Eugster, Anne
A1  - Dietz, Sevina
A1  - Loebel, Doreen
A1  - Lindner, Annett
A1  - Kuehn, Denise
A1  - Taranko, Anna E.
A1  - Heschel, Babett
A1  - Gavrisan, Anita
A1  - Ziegler, Anette-Gabriele
A1  - Aringer, Martin
A1  - Bonifacio, Ezio
T1  - Association of Dendritic Cell Signatures With Autoimmune Inflammation Revealed by Single-Cell Profiling
JF  - Arthrittis & Rheumatology
Y1  - 2018
U6  - https://doi.org/10.1002/art.40793
SN  - 2326-5191
SN  - 2326-5205
VL  - 71
IS  - 5
SP  - 817
EP  - 828
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Awan, Asad Bashir
A1  - Schiebel, Juliane
A1  - Boehm, Alexander
A1  - Nitschke, Joerg
A1  - Sarwar, Yasra
A1  - Schierack, Peter
A1  - Ali, Aamir
T1  - Association of biofilm formation and cytotoxic potential with multidrug resistance in clinical isolates of pseudomonas  aeruginosa
JF  - EXCLI Journal
N2  - Multidrug resistant (MDR) Pseudomonas aeruginosa having strong biofilm potential and virulence factors are a serious threat for hospitalized patients having compromised immunity In this study, 34 P. aeruginosa isolates of human origin (17 MDR and 17 non-MDR clinical isolates) were checked for biofilm formation potential in enriched and minimal media. The biofilms were detected using crystal violet method and a modified software package of the automated VideoScan screening method. Cytotoxic potential of the isolates was also investigated on HepG2, LoVo and T24 cell lines using automated VideoScan technology. Pulse field gel electrophoresis revealed 10 PFGE types in MDR and 8 in non-MDR isolates. Although all isolates showed biofilm formation potential, strong biofilm formation was found more in enriched media than in minimal media. Eight MDR isolates showed strong biofilm potential in both enriched and minimal media by both detection methods. Strong direct correlation between crystal violet and VideoScan methods was observed in identifying strong biofilm forming isolates. High cytotoxic effect was observed by 4 isolates in all cell lines used while 6 other isolates showed high cytotoxic effect on T24 cell line only. Strong association of multidrug resistance was found with biofilm formation as strong biofilms were observed significantly higher in MDR isolates (p-value < 0.05) than non-MDR isolates. No significant association of cytotoxic potential with multidrug resistance or biofilm formation was found (p-value > 0.05). The MDR isolates showing significant cytotoxic effects and strong biofilm formation impose a serious threat for hospitalized patients with weak immune system.
KW  - Pseudomonas aeruginosa
KW  - multidrug resistance
KW  - biofilm
KW  - cytotoxicity
KW  - VideoScan technology
Y1  - 2019
U6  - https://doi.org/10.17179/excli2018-1948
SN  - 1611-2156
VL  - 18
SP  - 79
EP  - 90
PB  - Leibniz Research Centre for Working Environment and Human Factors
CY  - Dortmund
ER  -