TY  - JOUR
A1  - Limanowski, Jakub
A1  - Lopes, Pedro
A1  - Keck, Janis
A1  - Baudisch, Patrick
A1  - Friston, Karl
A1  - Blankenburg, Felix
T1  - Action-dependent processing of touch in the human parietal operculum and posterior insula
JF  - Cerebral Cortex
N2  - Somatosensory input generated by one's actions (i.e., self-initiated body movements) is generally attenuated. Conversely, externally caused somatosensory input is enhanced, for example, during active touch and the haptic exploration of objects. Here, we used functional magnetic resonance imaging (fMRI) to ask how the brain accomplishes this delicate weighting of self-generated versus externally caused somatosensory components. Finger movements were either self-generated by our participants or induced by functional electrical stimulation (FES) of the same muscles. During half of the trials, electrotactile impulses were administered when the (actively or passively) moving finger reached a predefined flexion threshold. fMRI revealed an interaction effect in the contralateral posterior insular cortex (pIC), which responded more strongly to touch during self-generated than during FES-induced movements. A network analysis via dynamic causal modeling revealed that connectivity from the secondary somatosensory cortex via the pIC to the supplementary motor area was generally attenuated during self-generated relative to FES-induced movements-yet specifically enhanced by touch received during self-generated, but not FES-induced movements. Together, these results suggest a crucial role of the parietal operculum and the posterior insula in differentiating self-generated from externally caused somatosensory information received from one's moving limb.
KW  - active touch
KW  - dynamic causal modeling
KW  - insula
KW  - parietal operculum
KW  - somatosensation
Y1  - 2019
U6  - https://doi.org/10.1093/cercor/bhz111
SN  - 1047-3211
SN  - 1460-2199
VL  - 30
IS  - 2
SP  - 607
EP  - 617
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Gianelli, Claudia
A1  - Kühne, Katharina
A1  - Lo Presti, Sara
A1  - Mencaraglia, Silvia
A1  - Dalla Volta, Riccardo
T1  - Action processing in the motor system
BT  - Transcranial Magnetic Stimulation (TMS) evidence of shared mechanisms in the visual and linguistic modalities
JF  - Brain and cognition : a journal of experimental and clinical research
N2  - In two experiments, we compared the dynamics of corticospinal excitability when processing visually or linguistically presented tool-oriented hand actions in native speakers and sequential bilinguals. In a third experiment we used the same procedure to test non-motor, low-level stimuli, i.e. scrambled images and pseudo-words.
Stimuli were presented in sequence: pictures (tool + tool-oriented hand action or their scrambled counterpart) and words (tool noun + tool-action verb or pseudo-words). Experiment 1 presented German linguistic stimuli to native speakers, while Experiment 2 presented English stimuli to non-natives. Experiment 3 tested Italian native speakers. Single-pulse trascranial magnetic stimulation (spTMS) was applied to the left motor cortex at five different timings: baseline, 200 ms after tool/noun onset, 150, 350 and 500 ms after hand/verb onset with motor-evoked potentials (MEPs) recorded from the first dorsal interosseous (FDI) and abductor digiti minimi (ADM) muscles. 
We report strong similarities in the dynamics of corticospinal excitability across the visual and linguistic modalities. MEPs' suppression started as early as 150 ms and lasted for the duration of stimulus presentation (500 ms). Moreover, we show that this modulation is absent for stimuli with no motor content. Overall, our study supports the notion of a core, overarching system of action semantics shared by different modalities.
KW  - TMS
KW  - motor cortex
KW  - action observation
KW  - action language
KW  - motor
KW  - inhibition
KW  - motor-evoked potentials
Y1  - 2020
U6  - https://doi.org/10.1016/j.bandc.2019.105510
SN  - 0278-2626
SN  - 1090-2147
VL  - 139
PB  - Elsevier
CY  - San Diego
ER  - 
TY  - JOUR
A1  - Omane, Paul Okyere
A1  - Höhle, Barbara
T1  - Acquiring syntactic variability
BT  - The production of Wh-questions in children and adults speaking Akan
JF  - Frontiers in communication
N2  - This paper investigates the predictions of the Derivational Complexity Hypothesis by studying the acquisition of wh-questions in 4- and 5-year-old Akan-speaking children in an experimental approach using an elicited production and an elicited imitation task. Akan has two types of wh-question structures (wh-in-situ and wh-ex-situ questions), which allows an investigation of children’s acquisition of these two question structures and their preferences for one or the other. Our results show that adults prefer to use wh-ex-situ questions over wh-in-situ questions. The results from the children show that both age groups have the two question structures in their linguistic repertoire. However, they differ in their preferences in usage in the elicited production task: while the 5-year-olds preferred the wh-in-situ structure over the wh-ex-situ structure, the 4-year-olds showed a selective preference for the wh-in-situ structure in who-questions. These findings suggest a developmental change in wh-question preferences in Akan-learning children between 4 and 5 years of age with a so far unobserved u-shaped developmental pattern. In the elicited imitation task, all groups showed a strong tendency to maintain the structure of in-situ and ex-situ questions in repeating grammatical questions. When repairing ungrammatical ex-situ questions, structural changes to grammatical in-situ questions were hardly observed but the insertion of missing morphemes while keeping the ex-situ structure. Together, our findings provide only partial support for the Derivational Complexity Hypothesis.
KW  - Akan
KW  - wh-questions
KW  - wh-in-situ
KW  - wh-ex-situ
KW  - derivational complexity
KW  - language acquisition
Y1  - 2021
U6  - https://doi.org/10.3389/fcomm.2021.604951
SN  - 2297-900X
VL  - 2021
PB  - Frontiers Media
CY  - Lausanne,  Schweiz
ER  - 
TY  - JOUR
A1  - Lang, Judith
A1  - Bohn, Patrick
A1  - Bhat, Hilal
A1  - Jastrow, Holger
A1  - Walkenfort, Bernd
A1  - Cansiz, Feyza
A1  - Fink, Julian
A1  - Bauer, Michael
A1  - Schumacher, Fabian
A1  - Kleuser, Burkhard
A1  - Lang, Karl S.
T1  - Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
JF  - Nature Communications
N2  - Macrophages have important protective functions during infection with herpes simplex virus type 1 (HSV-1). However, molecular mechanisms that restrict viral propagation and protect from severe disease are unclear. Here we show that macrophages take up HSV-1 via endocytosis and transport the virions into multivesicular bodies (MVBs). In MVBs, acid ceramidase (aCDase) converts ceramide into sphingosine and increases the formation of sphingosine-rich intraluminal vesicles (ILVs). Once HSV-1 particles reach MVBs, sphingosine-rich ILVs bind to HSV-1 particles, which restricts fusion with the limiting endosomal membrane and prevents cellular infection. Lack of aCDase in macrophage cultures or in Asah1(-/-) mice results in replication of HSV-1 and Asah1(-/-) mice die soon after systemic or intravaginal inoculation. The treatment of macrophages with sphingosine enhancing compounds blocks HSV-1 propagation, suggesting a therapeutic potential of this pathway. In conclusion, aCDase loads ILVs with sphingosine, which prevents HSV-1 capsids from penetrating into the cytosol.
KW  - immunology
KW  - infection
KW  - membrane fusion
KW  - phagocytosis
KW  - sphingolipids
Y1  - 2020
U6  - https://doi.org/10.1038/s41467-020-15072-8
SN  - 2041-1723
VL  - 11
IS  - 1
SP  - 1
EP  - 15
PB  - Nature Publishing Group UK
CY  - London
ER  - 
TY  - JOUR
A1  - Laux, Eva-Maria
A1  - Wenger, Christian
A1  - Bier, Frank Fabian
A1  - Hoelzel, Ralph
T1  - AC electrokinetic immobilization of organic dye molecules
JF  - Analytical and bioanalytical chemistry : a merger of Fresenius' journal of analytical chemistry and Analusis
N2  - The application of inhomogeneous AC electric fields for molecular immobilization is a very fast and simple method that does not require any adaptions to the molecule's functional groups or charges. Here, the method is applied to a completely new category of molecules: small organic fluorescence dyes, whose dimensions amount to only 1 nm or even less. The presented setup and the electric field parameters used allow immobilization of dye molecules on the whole electrode surface as opposed to pure dielectrophoretic applications, where molecules are attracted only to regions of high electric field gradients, i.e., to the electrode tips and edges. In addition to dielectrophoresis and AC electrokinetic flow, molecular scale interactions and electrophoresis at short time scales are discussed as further mechanisms leading to migration and immobilization of the molecules.
KW  - AC electrokinetics
KW  - AC electrophoresis
KW  - Molecular dielectrophoresis
KW  - Interdigitated electrodes
KW  - Organic dyes
Y1  - 2020
U6  - https://doi.org/10.1007/s00216-020-02480-4
SN  - 1618-2642
SN  - 1618-2650
VL  - 412
IS  - 16
SP  - 3859
EP  - 3870
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Sajedi, Maryam
A1  - Krivenkov, Maxim
A1  - Marchenko, Dmitry
A1  - Varykhalov, Andrei
A1  - Sanchez-Barriga, Jaime
A1  - Rienks, Emile D. L.
A1  - Rader, Oliver
T1  - Absence of a giant Rashba effect in the valence band of lead halide perovskites
JF  - Physical review : B, Condensed matter and materials physics
N2  - For hybrid organic-inorganic as well as all-inorganic lead halide perovskites a Rashba effect has been invoked to explain the high efficiency in energy conversion by prohibiting direct recombination. Both a bulk and surface Rashba effect have been predicted. In the valence band of methylammonium (MA) lead bromide a Rashba effect has been reported by angle-resolved photoemission and circular dichroism with giant values of 7-11 eV angstrom. We present band dispersion measurements of MAPbBr(3) and spin-resolved photoemission of CsPbBr3 to show that a large Rashba effect detectable by photoemission or circular dichroism does not exist and cannot be the origin of the high effciency.
Y1  - 2020
U6  - https://doi.org/10.1103/PhysRevB.102.081116
SN  - 2469-9950
SN  - 2469-9969
VL  - 102
IS  - 8
PB  - American Institute of Physics; American Physical Society (APS)
CY  - Woodbury, NY
ER  - 
TY  - JOUR
A1  - Boekstegers, Felix
A1  - Marcelain, Katherine
A1  - Barahona Ponce, Carol
A1  - Baez Benavides, Pablo F.
A1  - Müller, Bettina
A1  - de Toro, Gonzalo
A1  - Retamales, Javier
A1  - Barajas, Olga
A1  - Ahumada, Monica
A1  - Aleksandrova, Krasimira
A1  - Bermejo, Justo Lorenzo
T1  - ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans
JF  - Cancer Epidemiology
N2  - Background: The first large-scale genome-wide association study of gallbladder cancer (GBC) recently identified and validated three susceptibility variants in the ABCB1 and ABCB4 genes for individuals of Indian descent. We investigated whether these variants were also associated with GBC risk in Chileans, who show the highest incidence of GBC worldwide, and in Europeans with a low GBC incidence.
Methods: This population-based study analysed genotype data from retrospective Chilean case-control (255 cases, 2042 controls) and prospective European cohort (108 cases, 181 controls) samples consistently with the original publication.
Results: Our results confirmed the reported associations for Chileans with similar risk effects. Particularly strong associations (per-allele odds ratios close to 2) were observed for Chileans with high Native American (=Mapuche) ancestry. No associations were noticed for Europeans, but the statistical power was low.
Conclusion: Taking full advantage of genetic and ethnic differences in GBC risk may improve the efficiency of current prevention programs.
KW  - cancer epidemiology
KW  - gallbladder cancer
KW  - native American ancestry
KW  - population-specific risk marker
Y1  - 2020
VL  - 65
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Durand, Virginie
A1  - Bentz, Stephan
A1  - Kwiatek, Grzegorz
A1  - Dresen, Georg
A1  - Wollin, Christopher
A1  - Heidbach, Oliver
A1  - Martinez-Garzon, Patricia
A1  - Cotton, Fabrice
A1  - Nurlu, Murat
A1  - Bohnhoff, Marco
T1  - A two-scale preparation phase preceded an M-w 5.8 earthquake in the sea of marmara offshore Istanbul, Turkey
JF  - Seismological research letters
N2  - We analyze the spatiotemporal evolution of seismicity during a sequence of moderate (an M-w 4.7 foreshock and M-w 5.8 mainshock) earthquakes occurring in September 2019 at the transition between a creeping and a locked segment of the North Anatolian fault in the central Sea of Marmara, northwest Turkey. To investigate in detail the seismicity evolution, we apply a matched-filter technique to continuous waveforms, thus reducing the magnitude threshold for detection. Sequences of foreshocks preceding the two largest events are clearly seen, exhibiting two different behaviors: a long-term activation of the seismicity along the entire fault segment and a short-term concentration around the epicenters of the large events. We suggest a two-scale preparation phase, with aseismic slip preparing the mainshock final rupture a few days before, and a cascade mechanism leading to the nucleation of the mainshock. Thus, our study shows a combination of seismic and aseismic slip during the foreshock sequence changing the strength of the fault, bringing it closer to failure.
Y1  - 2020
U6  - https://doi.org/10.1785/0220200110
SN  - 0895-0695
SN  - 1938-2057
VL  - 91
IS  - 6
SP  - 3139
EP  - 3147
CY  - Boulder
ER  - 
TY  - JOUR
A1  - Scheller, Frieder W.
A1  - Schmid, Rolf
T1  - A tribute to Isao Karube (1942-2020) and his influence on sensor science
JF  - Analytical and bioanalytical chemistry : a merger of Fresenius' journal of analytical chemistry, Analusis and Quimica analitica
KW  - Karube
KW  - Japan
KW  - biosensors
KW  - lifetime achievements
Y1  - 2020
U6  - https://doi.org/10.1007/s00216-020-02946-5
SN  - 1618-2642
SN  - 1618-2650
VL  - 412
IS  - 28
SP  - 7709
EP  - 7711
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Jacobs, Ingo
A1  - Wollny, Anna
A1  - Seidler, Juliana
A1  - Wochatz, Germar
T1  - A trait emotional intelligence perspective on schema modes
JF  - Scandinavian Journal of Psychology
N2  - Schema modes (ormodes) are a key concept in the theory underlying schema therapy. Modes have rarely been related to established models of personality traits. The present study thus investigates the associations between trait emotional intelligence (TEI) and 14 modes, and tests a global TEI-mode factors-general psychological distress mediation model. The study draws on self-report data from 173 inpatients from a German clinic for psychosomatic medicine. Global TEI correlated positively with both healthy modes (happy child and healthy adult) and negatively with 10 maladaptive modes. When modes were regressed on the four TEI factors, six (emotionality), five (well-being), four (sociability), and four (self-control) significant partial effects on 10 modes emerged. In the parallel mediation model, the mode factors internalization and compulsivity fully mediated the global TEI-general psychological distress link. Implications of the results for the integration of modes with traits in general and with TEI in particular as well as implications of low TEI as a transdiagnostic feature of personality malfunctioning are discussed.
KW  - externalization
KW  - internalization
KW  - level of personality functioning
KW  - mentalization
KW  - psychological distress
KW  - schema modes
KW  - trait emotional
KW  - intelligence
Y1  - 2020
U6  - https://doi.org/10.1111/sjop.12670
SN  - 0036-5564
SN  - 1467-9450
VL  - 62
IS  - 2
SP  - 227
EP  - 236
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Scheibel, Willy
A1  - Trapp, Matthias
A1  - Limberger, Daniel
A1  - Döllner, Jürgen Roland Friedrich
T1  - A taxonomy of treemap visualization techniques
JF  - Science and Technology Publications
N2  - A treemap is a visualization that has been specifically designed to facilitate the exploration of tree-structured data and, more general, hierarchically structured data. The family of visualization techniques that use a visual metaphor for parent-child relationships based “on the property of containment” (Johnson, 1993) is commonly referred to as treemaps. However, as the number of variations of treemaps grows, it becomes increasingly important to distinguish clearly between techniques and their specific characteristics. This paper proposes to discern between Space-filling Treemap TS, Containment Treemap TC, Implicit Edge Representation Tree TIE, and Mapped Tree TMT for classification of hierarchy visualization techniques and highlights their respective properties. This taxonomy is created as a hyponymy, i.e., its classes have an is-a relationship to one another: TS TC TIE TMT. With this proposal, we intend to stimulate a discussion on a more unambiguous classification of treemaps and, furthermore, broaden what is understood by the concept of treemap itself.
KW  - Treemaps
KW  - Taxonomy
Y1  - 2020
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Cao, Xianyong
A1  - Tian, Fang
A1  - Andreev, Andrei
A1  - Anderson, Patricia M.
A1  - Lozhkin, Anatoly V.
A1  - Bezrukova, Elena
A1  - Ni, Jian
A1  - Rudaya, Natalia
A1  - Stobbe, Astrid
A1  - Wieczorek, Mareike
A1  - Herzschuh, Ulrike
T1  - A taxonomically harmonized and temporally standardized fossil pollen dataset from Siberia covering the last 40 kyr
JF  - Earth System Science Data
N2  - Pollen records from Siberia are mostly absent in global or Northern Hemisphere synthesis works. Here we present a taxonomically harmonized and temporally standardized pollen dataset that was synthesized using 173 palynological records from Siberia and adjacent areas (northeastern Asia, 42-75 degrees N, 50-180 degrees E). Pollen data were taxonomically harmonized, i.e. the original 437 taxa were assigned to 106 combined pollen taxa. Age-depth models for all records were revised by applying a constant Bayesian age-depth modelling routine. The pollen dataset is available as count data and percentage data in a table format (taxa vs. samples), with age information for each sample. The dataset has relatively few sites covering the last glacial period between 40 and 11.5 ka (calibrated thousands of years before 1950 CE) particularly from the central and western part of the study area. In the Holocene period, the dataset has many sites from most of the area, with the exception of the central part of Siberia. Of the 173 pollen records, 81 % of pollen counts were downloaded from open databases (GPD, EPD, PANGAEA) and 10 % were contributions by the original data gatherers, while a few were digitized from publications. Most of the pollen records originate from peatlands (48 %) and lake sediments (33 %). Most of the records (83 %) have >= 3 dates, allowing the establishment of reliable chronologies. The dataset can be used for various purposes, including pollen data mapping (example maps for Larix at selected time slices are shown) as well as quantitative climate and vegetation reconstructions. The datasets for pollen counts and pollen percentages are available at https://doi.org/10.1594/PANGAEA.898616 (Cao et al., 2019a), also including the site information, data source, original publication, dating data, and the plant functional type for each pollen taxa.
KW  - Late Quaternary vegetation
KW  - Holocene environmental history
KW  - eastern continental Asia
KW  - plant macrofossil data
KW  - late pleistocene
KW  - paleoenvironmental records
KW  - Verkhoyansk mountains
KW  - climate dynamics
KW  - glacial maximum
KW  - Northern Asia
Y1  - 2020
U6  - https://doi.org/10.5194/essd-12-119-2020
SN  - 1866-3508
SN  - 1866-3516
VL  - 12
IS  - 1
SP  - 119
EP  - 135
PB  - Copernics Publications
CY  - Katlenburg-Lindau
ER  - 
TY  - JOUR
A1  - Putra, Muhammad Panji Islam Fajar
A1  - Pradhan, Prajal
A1  - Kropp, Jürgen
T1  - A systematic analysis of Water-Energy-Food security nexus
BT  - a South Asian case study
JF  - The science of the total environment : an international journal for scientific research into the environment and its relationship with man
N2  - Most South Asian countries have challenges in ensuring water, energy, and food (WEF) security, which are often interacting positively or negatively. To address these challenges, the nexus approach provides a framework to identify the interactions of the WEF sectors as an integrated system. However, most nexus studies only qualitatively discuss the interactions between these sectors. This study conducts a systematic analysis of the WEF security nexus in South Asia by using open data sources at the country scale. We analyze interactions between the WEF sectors statistically, defining positive and negative correlations between the WEF security indicators as synergies and trade-offs, respectively. By creating networks of the synergies and trade-offs, we further identify most positively and negatively influencing indicators in the WEF security nexus. We observe a larger share of trade-offs than synergies within the water and energy sectors and a larger share of synergies than trade-offs among the WEF sectors for South Asia. However, these observations vary across the South Asian countries. Our analysis highlights that strategies on promoting sustainable energy and discouraging fossil fuel use could have overall positive effects on the WEF security nexus in the countries. This study provides evidence for considering the WEF security nexus as an integrated system rather than just a combination of three different sectors or securities.
KW  - water security
KW  - food security
KW  - energy security
KW  - network analysis
KW  - water-energy-food nexus
KW  - sustainable development
Y1  - 2020
U6  - https://doi.org/10.1016/j.scitotenv.2020.138451
SN  - 0048-9697
SN  - 1879-1026
VL  - 728
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Irrgang, Andreas
A1  - Geier, Stephan
A1  - Kreuzer, Simon
A1  - Pelisoli, Ingrid Domingos
A1  - Heber, Ulrich
T1  - A stripped helium star in the potential black hole binary LB-1
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Context 
The recently claimed discovery of a massive (M-BH = 68(-13)(+11) M-circle dot) black hole in the Galactic solar neighborhood has led to controversial discussions because it severely challenges our current view of stellar evolution. 

Aims
A crucial aspect for the determination of the mass of the unseen black hole is the precise nature of its visible companion, the B-type star LSV +22 25. Because stars of different mass can exhibit B-type spectra during the course of their evolution, it is essential to obtain a comprehensive picture of the star to unravel its nature and, thus, its mass. 

Methods
To this end, we study the spectral energy distribution of LSV +22 25 and perform a quantitative spectroscopic analysis that includes the determination of chemical abundances for He, C, N, O, Ne, Mg, Al, Si, S, Ar, and Fe.

Results
Our analysis clearly shows that LSV +22 25 is not an ordinary main sequence B-type star. The derived abundance pattern exhibits heavy imprints of the CNO bi-cycle of hydrogen burning, that is, He and N are strongly enriched at the expense of C and O. Moreover, the elements Mg, Al, Si, S, Ar, and Fe are systematically underabundant when compared to normal main-sequence B-type stars. We suggest that LSV +22 25 is a stripped helium star and discuss two possible formation scenarios. Combining our photometric and spectroscopic results with the Gaia parallax, we infer a stellar mass of 1.1 +/- 0.5 M-circle dot. Based on the binary system's mass function, this yields a minimum mass of 2-3 M-circle dot for the compact companion, which implies that it may not necessarily be a black hole but a massive neutron- or main sequence star. 

Conclusions
The star LSV +22 25 has become famous for possibly having a very massive black hole companion. However, a closer look reveals that the star itself is a very intriguing object. Further investigations are necessary for complete characterization of this object.
KW  - stars: abundances
KW  - stars: chemically peculiar
KW  - stars: early-type
KW  - pulsars: individual: LS V+22 25
Y1  - 2020
U6  - https://doi.org/10.1051/0004-6361/201937343
SN  - 0004-6361
SN  - 1432-0746
VL  - 633
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Forbriger, Thomas
A1  - Gao, Lingli
A1  - Malischewsky, Peter
A1  - Ohrnberger, Matthias
A1  - Pan, Yudi
T1  - A single Rayleigh mode may exist with multiple values of phase-velocity at one frequency
JF  - Geophysical journal international
N2  - Other than commonly assumed in seismology, the phase velocity of Rayleigh waves is not necessarily a single-valued function of frequency. In fact, a single Rayleigh mode can exist with three different values of phase velocity at one frequency. We demonstrate this for the first higher mode on a realistic shallow seismic structure of a homogeneous layer of unconsolidated sediments on top of a half-space of solid rock (LOH). In the case of LOH a significant contrast to the half-space is required to produce the phenomenon. In a simpler structure of a homogeneous layer with fixed (rigid) bottom (LFB) the phenomenon exists for values of Poisson's ratio between 0.19 and 0.5 and is most pronounced for P-wave velocity being three times S-wave velocity (Poisson's ratio of 0.4375). A pavement-like structure (PAV) of two layers on top of a half-space produces the multivaluedness for the fundamental mode. Programs for the computation of synthetic dispersion curves are prone to trouble in such cases. Many of them use mode-follower algorithms which loose track of the dispersion curve and miss the multivalued section. We show results for well established programs. Their inability to properly handle these cases might be one reason why the phenomenon of multivaluedness went unnoticed in seismological Rayleigh wave research for so long. For the very same reason methods of dispersion analysis must fail if they imply wave number k(l)(omega) for the lth Rayleigh mode to be a single-valued function of frequency.. This applies in particular to deconvolution methods like phase-matched filters. We demonstrate that a slant-stack analysis fails in the multivalued section, while a Fourier-Bessel transformation captures the complete Rayleigh-wave signal. Waves of finite bandwidth in the multivalued section propagate with positive group-velocity and negative phase-velocity. Their eigenfunctions appear conventional and contain no conspicuous feature.
KW  - Surface waves and free oscillations
KW  - Theoretical seismology
KW  - Wave
KW  - propagation
Y1  - 2020
U6  - https://doi.org/10.1093/gji/ggaa123
SN  - 0956-540X
SN  - 1365-246X
VL  - 222
IS  - 1
SP  - 582
EP  - 594
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Trindade, Ines
T1  - A shelter for the future
BT  - how WUSCHEL protects the shoot apical meristem from viral infection
JF  - Molecular plant
N2  - Plant development in its majority occurs post-embryonically
through the activity of local meristems that provide daughter cells
for the development of new organs. It has long been acknowledged
that the shoot apical meristem (SAM), which holds the stem cells
that will form above-ground organs, is recalcitrant to infection by
multiple pathogens, a crucial strategy to safeguard normal devel-
opment and subsequent generations. However, the molecular
mechanisms underlying SAM immunity remain largely unknown.
Y1  - 2020
U6  - https://doi.org/10.1016/j.molp.2020.11.009
SN  - 1674-2052
SN  - 1752-9867
VL  - 13
IS  - 12
SP  - 1675
EP  - 1675
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Grewing, Farouk F.
ED  - Ambühl, Annemarie
T1  - A Saturnalian poet as a literary critic
BT  - the carnivalesque poetics of Martial’s Apophoreta 183-196
JF  - thersites = tessellae – Birthday Issue for Christine Walde
N2  - This paper analyzes a specific section of Martial’s Apophoreta (Book 14), the ‘list’ of fourteen literary works that the poet-persona suggests to the reader as potentially suitable presents to give to friends on the occasion of the Saturnalia. It focuses strictly on the literary aspects of the poems and their underlying carnivalesque poetics. This includes an assessment of the logic of the poems’ arrangement and alleged inconsistencies. It is suggested that the section be read as a complex statement of Martial’s on various works and genres of Greek and Roman literature. The last couplet of the section (14.196), a certain Calvus’ work ‘On the use of cold water’ (De aquae frigidae usu), which is unidentifiable, receives particular attention, for previous scholarship has wasted a lot of ink on guessing what kind of work this may have been, thereby losing touch with the rich (meta-)poetics the couplet actually conveys.
KW  - Martial
KW  - epigram
KW  - Saturnalia
KW  - poetics
KW  - Apophoreta
Y1  - 2020
U6  - https://doi.org/10.34679/thersites.vol11.170
SN  - 2364-7612
VL  - 2020
IS  - 11
SP  - 176
EP  - 204
ER  - 
TY  - JOUR
A1  - Chelkh, W.
A1  - Ly, Ibrahim
A1  - Tarkhanov, Nikolai
T1  - A remark on the Laplace transform
JF  - Siberian Mathematical Journal
N2  - The study of the Cauchy problem for solutions of the heat equation in a cylindrical domain with data on the lateral surface by the Fourier method raises the problem of calculating the inverse Laplace transform of the entire function cos root z. This problem has no solution in the standard theory of the Laplace transform. We give an explicit formula for the inverse Laplace transform of cos root z using the theory of analytic functionals. This solution suits well to efficiently develop the regularization of solutions to Cauchy problems for parabolic equations with data on noncharacteristic surfaces.
KW  - Fourier-Laplace transform
KW  - distributions with one-sided support
KW  - holomorphic function
KW  - analytic functional
Y1  - 2020
U6  - https://doi.org/10.1134/S0037446620040151
SN  - 0037-4466
SN  - 1573-9260
VL  - 61
IS  - 4
SP  - 755
EP  - 762
PB  - Consultants Bureau, Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Powali, Debarchan
A1  - Sharma, Shubham
A1  - Mandal, Riddhi
A1  - Mitra, Supriyo
T1  - A reappraisal of the 2005 Kashmir (M-w 7.6) earthquake and its aftershocks
BT  - seismotectonics of NW Himalaya
JF  - Tectonophysics : international journal of geotectonics and the geology and physics of the interior of the earth
N2  - We study the source properties of the 2005 Kashmir earthquake and its aftershocks to unravel the seismotectonics of the NW Himalayan syntaxis. The mainshock and larger aftershocks have been simultaneously relocated using phase data. We use back-projection of high-frequency energy from multiple teleseismic arrays to model the spatio-temporal evolution of the mainshock rupture. Our analysis reveal a bilateral rupture, which initially propagated SE and then NW of the epicenter, with an average rupture velocity of similar to 2 km s(-1). The area of maximum energy release is parallel to and bound by the surface rupture. Incorporating rupture propagation and velocity, we model the mainshock as a line source using P- and SH-waveform inversion. Our result confirms that the mainshock occurred on a NE dipping (similar to 35 degrees) fault plane, with centroid depth of similar to 10 km. Integrated source time function show that majority of the energy was released in the first similar to 20 s, and was confined above the hypocenter. From waveform inverted fault dimension and seismic moment, we argue that the mainshock had an additional similar to 25 km blind rupture beyond the NW Himalayan syntaxis. Combining this with findings from previous studies, we conjecture that the blind rupture propagated NW of the syntaxis underneath a weak detachment overlain by infra-Cambrian salt layer, and terminated in a wedge thrust. All moderate-to-large aftershocks, NW of the mainshock rupture, are concentrated at the edge of the blind rupture termination. Source modeling of these aftershocks reveal thrust mechanism with centroid depths of 2-10 km, and fault planes oriented subparallel to the mainshock rupture. To study the influence of mainshock rupture on aftershock occurrence, we compute Coulomb failure stress on aftershock faults. All these aftershocks lie in the positive Coulomb stress change region. This suggest that the aftershocks have been triggered by either co-seismic or post-seismic slip on the mainshock fault.
KW  - Kashmir earthquake
KW  - Aftershocks
KW  - High frequency back-projection
KW  - Source
KW  - mechanism
KW  - Coulomb failure stress
KW  - Seismo-tectonics
Y1  - 2020
U6  - https://doi.org/10.1016/j.tecto.2020.228501
SN  - 0040-1951
SN  - 1879-3266
VL  - 789
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schaffenroth, Veronika
A1  - Casewell, Sarah L.
A1  - Schneider, D.
A1  - Kilkenny, David
A1  - Geier, Stephan
A1  - Heber, Ulrich
A1  - Irrgang, Andreas
A1  - Przybilla, Norbert
A1  - Marsh, Thomas R.
A1  - Littlefair, Stuart P.
A1  - Dhillon, Vik S.
T1  - A quantitative in-depth analysis of the prototype sdB plus BD system SDSS J08205+0008 revisited in the Gaia era
JF  - Monthly notices of the Royal Astronomical Society
N2  - Subdwarf B stars are core-helium-burning stars located on the extreme horizontal branch (EHB). Extensive mass loss on the red giant branch is necessary to form them. It has been proposed that substellar companions could lead to the required mass loss when they are engulfed in the envelope of the red giant star. J08205+0008 was the first example of a hot subdwarf star with a close, substellar companion candidate to be found. Here, we perform an in-depth re-analysis of this important system with much higher quality data allowing additional analysis methods. From the higher resolution spectra obtained with ESO-VLT/XSHOOTER, we derive the chemical abundances of the hot subdwarf as well as its rotational velocity. Using the Gaia parallax and a fit to the spectral energy distribution in the secondary eclipse, tight constraints to the radius of the hot subdwarf are derived. From a long-term photometric campaign, we detected a significant period decrease of -3.2(8) x 10(-12) dd(-1). This can be explained by the non-synchronized hot subdwarf star being spun up by tidal interactions forcing it to become synchronized. From the rate of period decrease we could derive the synchronization time-scale to be 4 Myr, much smaller than the lifetime on EHB. By combining all different methods, we could constrain the hot subdwarf to a mass of 0.39-0.50 M-circle dot and a radius of R-sdB = 0.194 +/- 0.008 R-circle dot, and the companion to 0.061-0.071 M-circle dot with a radius of R-comp = 0.092 +/- 0.005 R-circle dot, below the hydrogen-burning limit. We therefore confirm that the companion is most likely a massive brown dwarf.
KW  - stars: abundances
KW  - stars: atmospheres
KW  - stars: fundamental parameters
KW  - stars: horizontal branch
KW  - stars: low-mass
KW  - subdwarfs
Y1  - 2020
U6  - https://doi.org/10.1093/mnras/staa3661
SN  - 0035-8711
SN  - 1365-2966
VL  - 501
IS  - 3
SP  - 3847
EP  - 3870
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Lenz, Markus Alexander
ED  - Islam, Dayeh
T1  - A Prophet of Divine Wisdom?
BT  - Giambattista Vico and the Construction of the Pythagorean Myth
JF  - Philological Encounters
Special Issus: Early Modern 'New Sciences': Inquiries into Ibn Khaldun and Giambattista Vico
N2  - In the nineteenth century, the reception of Giambattista Vico’s writings came along with nationalist interpretations of his Scienza Nuova as an ‘Italian Science’. This tendency was based upon an increased examination of the role that the philosopher Pythagoras and his Italian school of Croton played in Vico’s hierarchical conception of the ancient Greek and Italian civilizations. Writers, archaeologists and historians used the New Science as a metonymic reference work for their own nationalist concepts by updating the Pythagorean myth in accordance with relevant narratives of exclusive genealogies concerning an ancient Italian wisdom. These narratives follow tendencies in Vico’s own writings that were quoted strategically and mixed with further interpretations of the Scienza Nuova as reliable testimonial for a glorious Italian history. A theological poet characterized by deeper insight into the secrets of nature and some parts of the divine providence, Pythagoras gains his special position in Vico’s general conception of knowledge.
KW  - Pythagoras
KW  - Cuoco
KW  - Mazzoldi;
KW  - prophet
KW  - Pythagorean myth
KW  - Italian nationalism
Y1  - 2020
UR  - https://brill.com/view/journals/phen/5/1/article-p50_4.xml
SN  - 2451-9189
SN  - 2451-9197
VL  - 5
IS  - 1
SP  - 50
EP  - 75
PB  - Brill
CY  - Leiden
ER  - 
TY  - JOUR
A1  - Paprotny, Dominik
A1  - Kreibich, Heidi
A1  - Morales-Napoles, Oswaldo
A1  - Wagenaar, Dennis
A1  - Castellarin, Attilio
A1  - Carisi, Francesca
A1  - Bertin, Xavier
A1  - Merz, Bruno
A1  - Schröter, Kai
T1  - A probabilistic approach to estimating residential losses from different flood types
JF  - Natural hazards : journal of the International Society for the Prevention and Mitigation of Natural Hazards
N2  - Residential assets, comprising buildings and household contents, are a major source of direct flood losses. Existing damage models are mostly deterministic and limited to particular countries or flood types. Here, we compile building-level losses from Germany, Italy and the Netherlands covering a wide range of fluvial and pluvial flood events. Utilizing a Bayesian network (BN) for continuous variables, we find that relative losses (i.e. loss relative to exposure) to building structure and its contents could be estimated with five variables: water depth, flow velocity, event return period, building usable floor space area and regional disposable income per capita. The model's ability to predict flood losses is validated for the 11 flood events contained in the sample. Predictions for the German and Italian fluvial floods were better than for pluvial floods or the 1993 Meuse river flood. Further, a case study of a 2010 coastal flood in France is used to test the BN model's performance for a type of flood not included in the survey dataset. Overall, the BN model achieved better results than any of 10 alternative damage models for reproducing average losses for the 2010 flood. An additional case study of a 2013 fluvial flood has also shown good performance of the model. The study shows that data from many flood events can be combined to derive most important factors driving flood losses across regions and time, and that resulting damage models could be applied in an open data framework.
KW  - fluvial floods
KW  - coastal floods
KW  - pluvial floods
KW  - Bayesian networks
KW  - flood
KW  - damage surveys
Y1  - 2020
U6  - https://doi.org/10.1007/s11069-020-04413-x
SN  - 0921-030X
SN  - 1573-0840
VL  - 105
IS  - 3
SP  - 2569
EP  - 2601
PB  - Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Smith, Garrett
A1  - Vasishth, Shravan
T1  - A principled approach to feature selection in models of sentence processing
JF  - Cognitive science : a multidisciplinary journal of anthropology, artificial intelligence, education, linguistics, neuroscience, philosophy, psychology ; journal of the Cognitive Science Society
N2  - Among theories of human language comprehension, cue-based memory retrieval has proven to be a useful framework for understanding when and how processing difficulty arises in the resolution of long-distance dependencies. Most previous work in this area has assumed that very general retrieval cues like [+subject] or [+singular] do the work of identifying (and sometimes misidentifying) a retrieval target in order to establish a dependency between words. However, recent work suggests that general, handpicked retrieval cues like these may not be enough to explain illusions of plausibility (Cunnings & Sturt, 2018), which can arise in sentences like The letter next to the porcelain plate shattered. Capturing such retrieval interference effects requires lexically specific features and retrieval cues, but handpicking the features is hard to do in a principled way and greatly increases modeler degrees of freedom. To remedy this, we use well-established word embedding methods for creating distributed lexical feature representations that encode information relevant for retrieval using distributed retrieval cue vectors. We show that the similarity between the feature and cue vectors (a measure of plausibility) predicts total reading times in Cunnings and Sturt's eye-tracking data. The features can easily be plugged into existing parsing models (including cue-based retrieval and self-organized parsing), putting very different models on more equal footing and facilitating future quantitative comparisons.
KW  - Cue‐based retrieval
KW  - plausibility
KW  - word embeddings
KW  - linguistic
KW  - features
Y1  - 2020
U6  - https://doi.org/10.1111/cogs.12918
SN  - 0364-0213
SN  - 1551-6709
VL  - 44
IS  - 12
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Malass, Ihsane
A1  - Tarkhanov, Nikolaj Nikolaevič
T1  - A perturbation of the de Rham complex
T1  - Возмущение комплекса де Рама
JF  - Journal of Siberian Federal University : Mathematics & Physics
JF  - Žurnal Sibirskogo Federalʹnogo Universiteta : Matematika i fizika
N2  - We consider a perturbation of the de Rham complex on a compact manifold with boundary. This perturbation goes beyond the framework of complexes, and so cohomology does not apply to it. On the other hand, its curvature is "small", hence there is a natural way to introduce an Euler characteristic and develop a Lefschetz theory for the perturbation. This work is intended as an attempt to develop a cohomology theory for arbitrary sequences of linear mappings.
N2  - Рассмотрим возмущение комплекса де Рама на компактном многообразии с краем. Это возмущение выходит за рамки комплексов, и поэтому когомологии к нему не относятся. С другой стороны, его кривизна "мала", поэтому существует естественный способ ввести характеристику Эйлера и разработать теорию Лефшеца для возмущения. Данная работа предназначена для попытки разработать теорию когомологий для произвольных последовательностей линейных отображений.
KW  - de Rham complex
KW  - cohomology
KW  - Hodge theory
KW  - Neumann problem
KW  - комплекс де Рама
KW  - когомологии
KW  - теория Ходжа
KW  - проблема Неймана
Y1  - 2020
U6  - https://doi.org/10.17516/1997-1397-2020-13-5-519-532
SN  - 1997-1397
SN  - 2313-6022
VL  - 13
IS  - 5
SP  - 519
EP  - 532
PB  - Siberian Federal University
CY  - Krasnojarsk
ER  - 
TY  - JOUR
A1  - Czapka, Sophia
A1  - Wotschack, Christiane
A1  - Klassert, Annegret
A1  - Festman, Julia
T1  - A path to the bilingual advantage
BT  - pairwise matching of individuals
JF  - Bilingualism : language and cognition
N2  - Matching participants (as suggested by Hope, 2015) may be one promising option for research on a potential bilingual advantage in executive functions (EF). In this study we first compared performances in three EF-tasks of a naturally heterogeneous sample of monolingual (n = 69, age = 9.0 y) and multilingual children (n = 57, age = 9.3 y). Secondly, we meticulously matched participants pairwise to obtain two highly homogeneous groups to rerun our analysis and investigate a potential bilingual advantage. The initally disadvantaged multilinguals (regarding socioeconomic status and German lexicon size) performed worse in updating and response inhibition, but similarly in interference inhibition. This indicates that superior EF compensate for the detrimental effects of the background variables. After matching children pairwise on age, gender, intelligence, socioeconomic status and German lexicon size, performances became similar except for interference inhibition. Here, an advantage for multilinguals in the form of globally reduced reaction times emerged, indicating a bilingual executive processing advantage.
KW  - executive functions
KW  - bilingualism
KW  - interference inhibition
KW  - pairwise
KW  - matching
KW  - primary school children
KW  - background variables
KW  - lexicon size
Y1  - 2019
U6  - https://doi.org/10.1017/S1366728919000166
SN  - 1366-7289
SN  - 1469-1841
VL  - 23
IS  - 2
SP  - 344
EP  - 354
PB  - Cambridge Univ. Press
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Großmann, Robert
A1  - Aranson, Igor S.
A1  - Peruani, Fernando
T1  - A particle-field approach bridges phase separation and collective motion in active matter
JF  - Nature Communications
N2  - Whereas self-propelled hard discs undergo motility-induced phase separation, self-propelled rods exhibit a variety of nonequilibrium phenomena, including clustering, collective motion, and spatio-temporal chaos. In this work, we present a theoretical framework representing active particles by continuum fields. This concept combines the simplicity of alignment-based models, enabling analytical studies, and realistic models that incorporate the shape of self-propelled objects explicitly. By varying particle shape from circular to ellipsoidal, we show how nonequilibrium stresses acting among self-propelled rods destabilize motility-induced phase separation and facilitate orientational ordering, thereby connecting the realms of scalar and vectorial active matter. Though the interaction potential is strictly apolar, both, polar and nematic order may emerge and even coexist. Accordingly, the symmetry of ordered states is a dynamical property in active matter. The presented framework may represent various systems including bacterial colonies, cytoskeletal extracts, or shaken granular media. Interacting self-propelled particles exhibit phase separation or collective motion depending on particle shape. A unified theory connecting these paradigms represents a major challenge in active matter, which the authors address here by modeling active particles as continuum fields.
Y1  - 2020
U6  - https://doi.org/10.1038/s41467-020-18978-5
SN  - 2041-1723
VL  - 11
IS  - 1
PB  - Nature Publishing Group
CY  - London
ER  - 
TY  - JOUR
A1  - Listek, Martin
A1  - Hönow, Anja
A1  - Gossen, Manfred
A1  - Hanack, Katja
T1  - A novel selection strategy for antibody producing hybridoma cells based on a new transgenic fusion cell line
JF  - Scientific Reports
N2  - The use of monoclonal antibodies is ubiquitous in science and biomedicine but the generation and validation process of antibodies is nevertheless complicated and time-consuming. To address these issues we developed a novel selective technology based on an artificial cell surface construct by which secreted antibodies were connected to the corresponding hybridoma cell when they possess the desired antigen-specificity. Further the system enables the selection of desired isotypes and the screening for potential cross-reactivities in the same context. For the design of the construct we combined the transmembrane domain of the EGF-receptor with a hemagglutinin epitope and a biotin acceptor peptide and performed a transposon-mediated transfection of myeloma cell lines. The stably transfected myeloma cell line was used for the generation of hybridoma cells and an antigen- and isotype-specific screening method was established. The system has been validated for globular protein antigens as well as for haptens and enables a fast and early stage selection and validation of monoclonal antibodies in one step.
KW  - Antibody generation
KW  - Assay systems
Y1  - 2019
U6  - https://doi.org/10.1038/s41598-020-58571-w
SN  - 2045-2322
VL  - 10
PB  - Macmillan Publishers Limited, part of Springer Nature
CY  - London
ER  - 
TY  - JOUR
A1  - Gostkowska-Lekner, Natalia Katarzyna
A1  - Wallacher, Dirk
A1  - Grimm, Nico
A1  - Habicht, Klaus
A1  - Hofmann, Tommy
T1  - A novel electrochemical anodization cell for the synthesis of mesoporous silicon
JF  - Review of scientific instruments : a monthly journal devoted to scientific instruments, apparatus, and techniques
N2  - A novel design of an electrochemical anodization cell dedicated to the synthesis of mesoporous, single-crystalline silicon is presented. First and foremost, the design principle follows user safety since electrochemical etching of silicon requires highly hazardous electrolytes based on hydrofluoric (HF) acid. The novel cell design allows for safe electrolyte handling prior, during, and post-etching. A peristaltic pump with HF-resistant fluoroelastomer tubing transfers electrolytes between dedicated reservoirs and the anodization cell. Due to the flexibility of the cell operation, different processing conditions can be realized providing a large parameter range for the attainable sample thickness, its porosity, and the mean pore size. Rapid etching on the order of several minutes to synthesize micrometer-thick porous silicon epilayers on bulk silicon is possible as well as long-time etching with continuous, controlled electrolyte flow for several days to prepare up to 1000 mu m thick self-supporting porous silicon membranes. A highly adaptable, LabVIEW((TM))-based control software allows for user-defined etching profiles.
Y1  - 2020
U6  - https://doi.org/10.1063/5.0008536
SN  - 0034-6748
SN  - 1089-7623
VL  - 91
IS  - 10
PB  - American Institute of Physics
CY  - Melville, NY
ER  - 
TY  - JOUR
A1  - Gómez-Nava, Luis
A1  - Grossmann, Robert
A1  - Hintsche, Marius
A1  - Beta, Carsten
A1  - Peruani, Fernando
T1  - A novel approach to chemotaxis
BT  - active particles guided by internal clocks
JF  - epl : a letters journal exploring the frontiers of physics
N2  - Motivated by the observation of non-exponential run-time distributions of bacterial swimmers, we propose a minimal phenomenological model for taxis of active particles whose motion is controlled by an internal clock. The ticking of the clock depends on an external concentration field, e.g., a chemical substance. We demonstrate that these particles can detect concentration gradients and respond to them by moving up- or down-gradient depending on the clock design, albeit measurements of these fields are purely local in space and instantaneous in time. Altogether, our results open a new route in the study of directional navigation: we show that the use of a clock to control motility actions represents a generic and versatile toolbox to engineer behavioral responses to external cues, such as light, chemical, or temperature gradients.
Y1  - 2020
U6  - https://doi.org/10.1209/0295-5075/130/68002
SN  - 0295-5075
SN  - 1286-4854
VL  - 130
IS  - 6
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Assagra, Yuri A.O.
A1  - Altafim, Ruy Alberto Pisani
A1  - do Carmo, Joao P.
A1  - Altafim, Ruy A.C.
A1  - Rychkov, Dmitry
A1  - Wirges, Werner
A1  - Gerhard, Reimund
T1  - A new route to piezo-polymer transducers: 3D printing of polypropylene ferroelectrets
JF  - IEEE transactions on dielectrics and electrical insulation
N2  - Here, a promising approach for producing piezo-polymer transducers in a one-step process is presented. Using 3D-printing technology and polypropylene (PP) filaments, we are able to print a two-layered film structure with regular cavities of precisely controlled size and shape. It is found that the 3D-printed samples exhibit piezoelectric coefficients up to 200 pC/N, similar to those of other PP ferroelectrets, and their temporal and thermal behavior is in good agreement with those known of PP ferroelectrets. The piezoelectric response strongly decreases for applied pressures above 20 kPa, as the pressure in the air-filled cavities strongly influences the overall elastic modulus of ferroelectrets.
KW  - 3D printing
KW  - polymer ferroelectrets
KW  - sensors and actuators
KW  - piezoelectrets
KW  - electret polymers
KW  - soft electro-active materials
KW  - functional materials
KW  - soft matter
Y1  - 2020
U6  - https://doi.org/10.1109/TDEI.2020.008461
SN  - 1070-9878
SN  - 1558-4135
VL  - 27
IS  - 5
SP  - 1668
EP  - 1674
PB  - Inst. of Electr. and Electronics Engineers
CY  - Piscataway
ER  - 
TY  - JOUR
A1  - Obbard, Darren J.
A1  - Shi, Mang
A1  - Roberts, Katherine E.
A1  - Longdon, Ben
A1  - Dennis, Alice B.
T1  - A new lineage of segmented RNA viruses infecting animals
JF  - Virus Evolution
N2  - Metagenomic sequencing has revolutionised our knowledge of virus diversity, with new virus sequences being reported faster than ever before. However, virus discovery from metagenomic sequencing usually depends on detectable homology: without a sufficiently close relative, so-called ‘dark’ virus sequences remain unrecognisable. An alternative approach is to use virus-identification methods that do not depend on detecting homology, such as virus recognition by host antiviral immunity. For example, virus-derived small RNAs have previously been used to propose ‘dark’ virus sequences associated with the Drosophilidae (Diptera). Here, we combine published Drosophila data with a comprehensive search of transcriptomic sequences and selected meta-transcriptomic datasets to identify a completely new lineage of segmented positive-sense single-stranded RNA viruses that we provisionally refer to as the Quenyaviruses. Each of the five segments contains a single open reading frame, with most encoding proteins showing no detectable similarity to characterised viruses, and one sharing a small number of residues with the RNA-dependent RNA polymerases of single- and double-stranded RNA viruses. Using these sequences, we identify close relatives in approximately 20 arthropods, including insects, crustaceans, spiders, and a myriapod. Using a more conserved sequence from the putative polymerase, we further identify relatives in meta-transcriptomic datasets from gut, gill, and lung tissues of vertebrates, reflecting infections of vertebrates or of their associated parasites. Our data illustrate the utility of small RNAs to detect viruses with limited sequence conservation, and provide robust evidence for a new deeply divergent and phylogenetically distinct RNA virus lineage.
KW  - metagenome
KW  - RNA virus
KW  - dark virus
KW  - arthropod
KW  - RNA interference
Y1  - 2020
U6  - https://doi.org/10.1093/ve/vez061
SN  - 2057-1577
VL  - 6
IS  - 1
SP  - 1
EP  - 10
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Schittko, Conrad
A1  - Bernard-Verdier, Maud
A1  - Heger, Tina
A1  - Buchholz, Sascha
A1  - Kowarik, Ingo
A1  - von der Lippe, Moritz
A1  - Seitz, Birgit
A1  - Joshi, Jasmin Radha
A1  - Jeschke, Jonathan M.
T1  - A multidimensional framework for measuring biotic novelty: How novel is a community?
JF  - Global Change Biology
N2  - Anthropogenic changes in climate, land use, and disturbance regimes, as well as introductions of non-native species can lead to the transformation of many ecosystems. The resulting novel ecosystems are usually characterized by species assemblages that have not occurred previously in a given area. Quantifying the ecological novelty of communities (i.e., biotic novelty) would enhance the understanding of environmental change. However, quantification remains challenging since current novelty metrics, such as the number and/or proportion of non-native species in a community, fall short of considering both functional and evolutionary aspects of biotic novelty. Here, we propose the Biotic Novelty Index (BNI), an intuitive and flexible multidimensional measure that combines (a) functional differences between native and non-native introduced species with (b) temporal dynamics of species introductions. We show that the BNI is an additive partition of Rao's quadratic entropy, capturing the novel interaction component of the community's functional diversity. Simulations show that the index varies predictably with the relative amount of functional novelty added by recently arrived species, and they illustrate the need to provide an additional standardized version of the index. We present a detailed R code and two applications of the BNI by (a) measuring changes of biotic novelty of dry grassland plant communities along an urbanization gradient in a metropolitan region and (b) determining the biotic novelty of plant species assemblages at a national scale. The results illustrate the applicability of the index across scales and its flexibility in the use of data of different quality. Both case studies revealed strong connections between biotic novelty and increasing urbanization, a measure of abiotic novelty. We conclude that the BNI framework may help building a basis for better understanding the ecological and evolutionary consequences of global change.
KW  - alien species
KW  - biological invasions
KW  - coexistence
KW  - ecological novelty
KW  - functional diversity
KW  - novel ecosystems
KW  - novel species
KW  - standard metrics
Y1  - 2019
VL  - 26
IS  - 8
PB  - John Wiley & Sons, Inc.
CY  - New Jersey
ER  - 
TY  - JOUR
A1  - Winkelbeiner, Nicola Lisa
A1  - Wandt, Viktoria Klara Veronika
A1  - Ebert, Franziska
A1  - Lossow, Kristina
A1  - Bankoglu, Ezgi E.
A1  - Martin, Maximilian
A1  - Mangerich, Aswin
A1  - Stopper, Helga
A1  - Bornhorst, Julia
A1  - Kipp, Anna Patricia
A1  - Schwerdtle, Tanja
T1  - A Multi-Endpoint Approach to Base Excision Repair Incision Activity Augmented by PARylation and DNA Damage Levels in Mice
BT  - Impact of Sex and Age
JF  - International Journal of Molecular Sciences
N2  - Investigation of processes that contribute to the maintenance of genomic stability is one crucial factor in the attempt to understand mechanisms that facilitate ageing. The DNA damage response (DDR) and DNA repair mechanisms are crucial to safeguard the integrity of DNA and to prevent accumulation of persistent DNA damage. Among them, base excision repair (BER) plays a decisive role. BER is the major repair pathway for small oxidative base modifications and apurinic/apyrimidinic (AP) sites. We established a highly sensitive non-radioactive assay to measure BER incision activity in murine liver samples. Incision activity can be assessed towards the three DNA lesions 8-oxo-2’-deoxyguanosine (8-oxodG), 5-hydroxy-2’-deoxyuracil (5-OHdU), and an AP site analogue. We applied the established assay to murine livers of adult and old mice of both sexes. Furthermore, poly(ADP-ribosyl)ation (PARylation) was assessed, which is an important determinant in DDR and BER. Additionally, DNA damage levels were measured to examine the overall damage levels. No impact of ageing on the investigated endpoints in liver tissue were found. However, animal sex seems to be a significant impact factor, as evident by sex-dependent alterations in all endpoints investigated. Moreover, our results revealed interrelationships between the investigated endpoints indicative for the synergetic mode of action of the cellular DNA integrity maintaining machinery.
KW  - maintenance of genomic integrity
KW  - ageing
KW  - sex
KW  - DNA damage
KW  - base excision repair (incision activity)
KW  - DNA damage response
KW  - poly(ADP-ribosyl)ation
KW  - liver
Y1  - 2020
U6  - https://doi.org/10.3390/ijms21186600
SN  - 1422-0067
VL  - 21
IS  - 18
PB  - Molecular Diversity Preservation International
CY  - Basel
ER  - 
TY  - JOUR
A1  - Hartung, Niklas
A1  - Borghardt, Jens Markus
T1  - A mechanistic framework for a priori pharmacokinetic predictions of orally inhaled drugs
JF  - PLoS Computational Biology : a new community journal
N2  - Author summary <br /> The use of orally inhaled drugs for treating lung diseases is appealing since they have the potential for lung selectivity, i.e. high exposure at the site of action -the lung- without excessive side effects. However, the degree of lung selectivity depends on a large number of factors, including physiochemical properties of drug molecules, patient disease state, and inhalation devices. To predict the impact of these factors on drug exposure and thereby to understand the characteristics of an optimal drug for inhalation, we develop a predictive mathematical framework (a "pharmacokinetic model"). In contrast to previous approaches, our model allows combining knowledge from different sources appropriately and its predictions were able to adequately predict different sets of clinical data. Finally, we compare the impact of different factors and find that the most important factors are the size of the inhaled particles, the affinity of the drug to the lung tissue, as well as the rate of drug dissolution in the lung. In contrast to the common belief, the solubility of a drug in the lining fluids is not found to be relevant. These findings are important to understand how inhaled drugs should be designed to achieve best treatment results in patients. <br /> The fate of orally inhaled drugs is determined by pulmonary pharmacokinetic processes such as particle deposition, pulmonary drug dissolution, and mucociliary clearance. Even though each single process has been systematically investigated, a quantitative understanding on the interaction of processes remains limited and therefore identifying optimal drug and formulation characteristics for orally inhaled drugs is still challenging. To investigate this complex interplay, the pulmonary processes can be integrated into mathematical models. However, existing modeling attempts considerably simplify these processes or are not systematically evaluated against (clinical) data. In this work, we developed a mathematical framework based on physiologically-structured population equations to integrate all relevant pulmonary processes mechanistically. A tailored numerical resolution strategy was chosen and the mechanistic model was evaluated systematically against data from different clinical studies. Without adapting the mechanistic model or estimating kinetic parameters based on individual study data, the developed model was able to predict simultaneously (i) lung retention profiles of inhaled insoluble particles, (ii) particle size-dependent pharmacokinetics of inhaled monodisperse particles, (iii) pharmacokinetic differences between inhaled fluticasone propionate and budesonide, as well as (iv) pharmacokinetic differences between healthy volunteers and asthmatic patients. Finally, to identify the most impactful optimization criteria for orally inhaled drugs, the developed mechanistic model was applied to investigate the impact of input parameters on both the pulmonary and systemic exposure. Interestingly, the solubility of the inhaled drug did not have any relevant impact on the local and systemic pharmacokinetics. Instead, the pulmonary dissolution rate, the particle size, the tissue affinity, and the systemic clearance were the most impactful potential optimization parameters. In the future, the developed prediction framework should be considered a powerful tool for identifying optimal drug and formulation characteristics.
Y1  - 2020
U6  - https://doi.org/10.1371/journal.pcbi.1008466
SN  - 1553-734X
SN  - 1553-7358
VL  - 16
IS  - 12
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Malem-Shinitski, Noa
A1  - Opper, Manfred
A1  - Reich, Sebastian
A1  - Schwetlick, Lisa
A1  - Seelig, Stefan A.
A1  - Engbert, Ralf
T1  - A mathematical model of local and global attention in natural scene viewing
JF  - PLoS Computational Biology : a new community journal
N2  - Author summary <br /> Switching between local and global attention is a general strategy in human information processing. We investigate whether this strategy is a viable approach to model sequences of fixations generated by a human observer in a free viewing task with natural scenes. Variants of the basic model are used to predict the experimental data based on Bayesian inference. Results indicate a high predictive power for both aggregated data and individual differences across observers. The combination of a novel model with state-of-the-art Bayesian methods lends support to our two-state model using local and global internal attention states for controlling eye movements. <br /> Understanding the decision process underlying gaze control is an important question in cognitive neuroscience with applications in diverse fields ranging from psychology to computer vision. The decision for choosing an upcoming saccade target can be framed as a selection process between two states: Should the observer further inspect the information near the current gaze position (local attention) or continue with exploration of other patches of the given scene (global attention)? Here we propose and investigate a mathematical model motivated by switching between these two attentional states during scene viewing. The model is derived from a minimal set of assumptions that generates realistic eye movement behavior. We implemented a Bayesian approach for model parameter inference based on the model's likelihood function. In order to simplify the inference, we applied data augmentation methods that allowed the use of conjugate priors and the construction of an efficient Gibbs sampler. This approach turned out to be numerically efficient and permitted fitting interindividual differences in saccade statistics. Thus, the main contribution of our modeling approach is two-fold; first, we propose a new model for saccade generation in scene viewing. Second, we demonstrate the use of novel methods from Bayesian inference in the field of scan path modeling.
Y1  - 2020
U6  - https://doi.org/10.1371/journal.pcbi.1007880
SN  - 1553-734X
SN  - 1553-7358
VL  - 16
IS  - 12
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - von Specht, Sebastian
A1  - Cotton, Fabrice
T1  - A link between machine learning and optimization in ground-motion model development
BT  - weighted mixed-effects regression with data-driven probabilistic earthquake classification
JF  - Bulletin of the Seismological Society of America
N2  - The steady increase of ground-motion data not only allows new possibilities but also comes with new challenges in the development of ground-motion models (GMMs). Data classification techniques (e.g., cluster analysis) do not only produce deterministic classifications but also probabilistic classifications (e.g., probabilities for each datum to belong to a given class or cluster). One challenge is the integration of such continuous classification in regressions for GMM development such as the widely used mixed-effects model. We address this issue by introducing an extension of the mixed-effects model to incorporate data weighting. The parameter estimation of the mixed-effects model, that is, fixed-effects coefficients of the GMMs and the random-effects variances, are based on the weighted likelihood function, which also provides analytic uncertainty estimates. The data weighting permits for earthquake classification beyond the classical, expert-driven, binary classification based, for example, on event depth, distance to trench, style of faulting, and fault dip angle. We apply Angular Classification with Expectation-maximization, an algorithm to identify clusters of nodal planes from focal mechanisms to differentiate between, for example, interface- and intraslab-type events. Classification is continuous, that is, no event belongs completely to one class, which is taken into account in the ground-motion modeling. The theoretical framework described in this article allows for a fully automatic calibration of ground-motion models using large databases with automated classification and processing of earthquake and ground-motion data. As an example, we developed a GMM on the basis of the GMM by Montalva et al. (2017) with data from the strong-motion flat file of Bastias and Montalva (2016) with similar to 2400 records from 319 events in the Chilean subduction zone. Our GMM with the data-driven classification is comparable to the expert-classification-based model. Furthermore, the model shows temporal variations of the between-event residuals before and after large earthquakes in the region.
Y1  - 2020
U6  - https://doi.org/10.1785/0120190133
SN  - 0037-1106
SN  - 1943-3573
VL  - 110
IS  - 6
SP  - 2777
EP  - 2800
PB  - Seismological Society of America
CY  - Albany
ER  - 
TY  - JOUR
A1  - Tiwari, Abhishek
A1  - Prakash, Jyoti
A1  - Groß, Sascha
A1  - Hammer, Christian
T1  - A large scale analysis of Android
BT  - Web hybridization
JF  - The journal of systems and software
N2  - Many Android applications embed webpages via WebView components and execute JavaScript code within Android. Hybrid applications leverage dedicated APIs to load a resource and render it in a WebView. Furthermore, Android objects can be shared with the JavaScript world. However, bridging the interfaces of the Android and JavaScript world might also incur severe security threats: Potentially untrusted webpages and their JavaScript might interfere with the Android environment and its access to native features.
No general analysis is currently available to assess the implications of such hybrid apps bridging the two worlds. To understand the semantics and effects of hybrid apps, we perform a large-scale study on the usage of the hybridization APIs in the wild. We analyze and categorize the parameters to hybridization APIs for 7,500 randomly selected and the 196 most popular applications from the Google Playstore as well as 1000 malware samples. Our results advance the general understanding of hybrid applications, as well as implications for potential program analyses, and the current security situation: We discovered thousands of flows of sensitive data from Android to JavaScript, the vast majority of which could flow to potentially untrustworthy code. Our analysis identified numerous web pages embedding vulnerabilities, which we exemplarily exploited. Additionally, we discovered a multitude of applications in which potentially untrusted JavaScript code may interfere with (trusted) Android objects, both in benign and malign applications.
KW  - Android hybrid apps
KW  - static analysis
KW  - information flow control
Y1  - 2020
U6  - https://doi.org/10.1016/j.jss.2020.110775
SN  - 0164-1212
SN  - 1873-1228
VL  - 170
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Zhang, Youjun
A1  - Chen, Moxian
A1  - Siemiatkowska, Beata
A1  - Toleco, Mitchell Rey
A1  - Jing, Yue
A1  - Strotmann, Vivien
A1  - Zhang, Jianghua
A1  - Stahl, Yvonne
A1  - Fernie, Alisdair
T1  - A highly efficient agrobacterium-mediated method for transient gene expression and functional studies in multiple plant species
JF  - Plant Communications
N2  - Although the use of stable transformation technology has led to great insight into gene function, its application in high-throughput studies remains arduous. Agro-infiltration have been widely used in species such as Nicotiana benthamiana for the rapid detection of gene expression and protein interaction analysis, but this technique does not work efficiently in other plant species, including Arabidopsis thaliana. As an efficient high-throughput transient expression system is currently lacking in the model plant species A. thaliana, we developed a method that is characterized by high efficiency, reproducibility, and suitability for transient expression of a variety of functional proteins in A. thaliana and 7 other plant species, including Brassica oleracea, Capsella rubella, Thellungiella salsuginea, Thellungiella halophila, Solanum tuberosum, Capsicum annuum, and N. benthamiana. Efficiency of this method was independently verified in three independent research facilities, pointing to the robustness of this technique. Furthermore, in addition to demonstrating the utility of this technique in a range of species, we also present a case study employing this method to assess protein-protein interactions in the sucrose biosynthesis pathway in Arabidopsis.
KW  - transient expression
KW  - agro-infiltration
KW  - subcellular localization
KW  - protein-protein interaction
Y1  - 2019
SN  - 2590-3462
VL  - 1
IS  - 5
PB  - Science Direct
CY  - New York
ER  - 
TY  - JOUR
A1  - Fischer, Eric W.
A1  - Werther, Michael
A1  - Bouakline, Foudhil
A1  - Saalfrank, Peter
T1  - A hierarchical effective mode approach to phonon-driven multilevel vibrational relaxation dynamics at surfaces
JF  - The journal of chemical physics : bridges a gap between journals of physics and journals of chemistry
N2  - We discuss an efficient Hierarchical Effective Mode (HEM) representation of a high-dimensional harmonic oscillator bath, which describes phonon-driven vibrational relaxation of an adsorbate-surface system, namely, deuterium adsorbed on Si(100). Starting from the original Hamiltonian of the adsorbate-surface system, the HEM representation is constructed via iterative orthogonal transformations, which are efficiently implemented with Householder matrices. The detailed description of the HEM representation and its construction are given in the second quantization representation. The hierarchical nature of this representation allows access to the exact quantum dynamics of the adsorbate-surface system over finite time intervals, controllable via the truncation order of the hierarchy. To study the convergence properties of the effective mode representation, we solve the time-dependent Schrodinger equation of the truncated system-bath HEM Hamiltonian, with the help of the multilayer extension of the Multiconfigurational Time-Dependent Hartree (ML-MCTDH) method. The results of the HEM representation are compared with those obtained with a quantum-mechanical tier-model. The convergence of the HEM representation with respect to the truncation order of the hierarchy is discussed for different initial conditions of the adsorbate-surface system. The combination of the HEM representation with the ML-MCTDH method provides information on the time evolution of the system (adsorbate) and multiple effective modes of the bath (surface). This permits insight into mechanisms of vibration-phonon coupling of the adsorbate-surface system, as well as inter-mode couplings of the effective bath.
Y1  - 2020
U6  - https://doi.org/10.1063/5.0017716
SN  - 0021-9606
SN  - 1089-7690
VL  - 153
IS  - 6
PB  - American Institute of Physics
CY  - Melville
ER  - 
TY  - JOUR
A1  - Hartlieb, Matthias
A1  - Mansfield, Edward D. H.
A1  - Perrier, Sebastien
T1  - A guide to supramolecular polymerizations
JF  - Polymer Chemistry
N2  - Supramolecular polymers or fibers are non-covalent assemblies of unimeric building blocks connected by secondary interactions such as hydrogen bonds or pi-pi interactions. Such structures hold enormous potential in the development of future materials, as their non-covalent nature makes them highly modular and adaptive. Within this review we aim to provide a broad overview over the area of linear supramolecular polymers including the different mechanisms of their polymerization as well as methods essential for their characterization. The different non-covalent interactions able to form supramolecular polymers are discussed, and key examples for each species are shown. Particular emphasis is laid on the development of living supramolecular polymerization able to produce fibers with a controlled length and low length dispersity, and even enable the production of supramolecular block copolymers. Another important and very recent field is the development of out-of-equilibrium supramolecular polymers, where the polymerization process can be temporally controlled enabling access to highly adaptive materials.
Y1  - 2020
U6  - https://doi.org/10.1039/c9py01342c
SN  - 1759-9954
SN  - 1759-9962
VL  - 11
IS  - 6
SP  - 1083
EP  - 1110
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Weatherill, Graeme
A1  - Cotton, Fabrice
T1  - A ground motion logic tree for seismic hazard analysis in the stable cratonic region of Europe
BT  - regionalisation, model selection and development of a scaled backbone approach
JF  - Bulletin of earthquake engineering : official publication of the European Association for Earthquake Engineering
N2  - Regions of low seismicity present a particular challenge for probabilistic seismic hazard analysis when identifying suitable ground motion models (GMMs) and quantifying their epistemic uncertainty. The 2020 European Seismic Hazard Model adopts a scaled backbone approach to characterise this uncertainty for shallow seismicity in Europe, incorporating region-to-region source and attenuation variability based on European strong motion data. This approach, however, may not be suited to stable cratonic region of northeastern Europe (encompassing Finland, Sweden and the Baltic countries), where exploration of various global geophysical datasets reveals that its crustal properties are distinctly different from the rest of Europe, and are instead more closely represented by those of the Central and Eastern United States. Building upon the suite of models developed by the recent NGA East project, we construct a new scaled backbone ground motion model and calibrate its corresponding epistemic uncertainties. The resulting logic tree is shown to provide comparable hazard outcomes to the epistemic uncertainty modelling strategy adopted for the Eastern United States, despite the different approaches taken. Comparison with previous GMM selections for northeastern Europe, however, highlights key differences in short period accelerations resulting from new assumptions regarding the characteristics of the reference rock and its influence on site amplification.
KW  - ground motion models
KW  - stable craton
KW  - regionalisation
KW  - epistemic
KW  - uncertainty
KW  - Europe
Y1  - 2020
U6  - https://doi.org/10.1007/s10518-020-00940-x
SN  - 1570-761X
SN  - 1573-1456
VL  - 18
IS  - 14
SP  - 6119
EP  - 6148
PB  - Springer Science + Business Media B.V.
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Reeg, Jette
A1  - Heine, Simon
A1  - Mihan, Christine
A1  - McGee, Sean
A1  - Preuss, Thomas G.
A1  - Jeltsch, Florian
T1  - A graphical user interface for the plant community model IBC-grass
JF  - Plos One
N2  - Plants located adjacent to agricultural fields are important for maintaining biodiversity in semi-natural landscapes. To avoid undesired impacts on these plants due to herbicide application on the arable fields, regulatory risk assessments are conducted prior to registration to ensure proposed uses of plant protection products do not present an unacceptable risk. The current risk assessment approach for these non-target terrestrial plants (NTTPs) examines impacts at the individual-level as a surrogate approach for protecting the plant community due to the inherent difficulties of directly assessing population or community level impacts. However, modelling approaches are suitable higher tier tools to upscale individual-level effects to community level. IBC-grass is a sophisticated plant community model, which has already been applied in several studies. However, as it is a console application software, it was not deemed sufficiently user-friendly for risk managers and assessors to be conveniently operated without prior expertise in ecological models. Here, we present a user-friendly and open source graphical user interface (GUI) for the application of IBC-grass in regulatory herbicide risk assessment. It facilitates the use of the plant community model for predicting long-term impacts of herbicide applications on NTTP communities. The GUI offers two options to integrate herbicide impacts: (1) dose responses based on current standard experiments (acc. to testing guidelines) and (2) based on specific effect intensities. Both options represent suitable higher tier options for future risk assessments of NTTPs as well as for research on the ecological relevance of effects.
Y1  - 2020
U6  - https://doi.org/10.1371/journal.pone.0230012
SN  - 1932-6203
VL  - 15
IS  - 3
PB  - Plos 1
CY  - San Francisco
ER  - 
TY  - JOUR
A1  - Zass, Alexander
T1  - A Gibbs point process of diffusions: Existence and uniqueness
JF  - Lectures in pure and applied mathematics
KW  - random point processes
KW  - statistical mechanics
KW  - stochastic analysis
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-471951
SN  - 978-3-86956-485-2
SN  - 2199-4951
SN  - 2199-496X
IS  - 6
SP  - 13
EP  - 22
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Jarecki, Jana B.
A1  - Tan, Jolene H.
A1  - Jenny, Mirjam
T1  - A framework for building cognitive process models
JF  - Psychonomic bulletin & review : a journal of the Psychonomic Society
N2  - The termprocess modelis widely used, but rarely agreed upon. This paper proposes a framework for characterizing and building cognitive process models. Process models model not only inputs and outputs but also model the ongoing information transformations at a given level of abstraction. We argue that the following dimensions characterize process models: They have a scope that includes different levels of abstraction. They specify a hypothesized mental information transformation. They make predictions not only for the behavior of interest but also for processes. The models' predictions for the processes can be derived from the input, without reverse inference from the output data. Moreover, the presumed information transformation steps are not contradicting current knowledge of human cognitive capacities. Lastly, process models require a conceptual scope specifying levels of abstraction for the information entering the mind, the proposed mental events, and the behavior of interest. This framework can be used for refining models before testing them or after testing them empirically, and it does not rely on specific modeling paradigms. It can be a guideline for developing cognitive process models. Moreover, the framework can advance currently unresolved debates about which models belong to the category of process models.
KW  - cognitive process model
KW  - cognitive model
KW  - computational model
KW  - definitions
KW  - Marr's levels
Y1  - 2020
U6  - https://doi.org/10.3758/s13423-020-01747-2
SN  - 1069-9384
SN  - 1531-5320
VL  - 27
IS  - 6
SP  - 1218
EP  - 1229
PB  - Springer
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Xiao, Shangbin
A1  - Liu, Liu
A1  - Wang, Wei
A1  - Lorke, Andreas
A1  - Woodhouse, Jason Nicholas
A1  - Grossart, Hans-Peter
T1  - A Fast-Response Automated Gas Equilibrator (FaRAGE) for continuous in situ measurement of CH4 and CO2 dissolved in water
JF  - Hydrology and earth system sciences : HESS
N2  - Biogenic greenhouse gas emissions, e.g., of methane (CH4) and carbon dioxide (CO2) from inland waters, contribute substantially to global warming. In aquatic systems, dissolved greenhouse gases are highly heterogeneous in both space and time. To better understand the biological and physical processes that affect sources and sinks of both CH4 and CO2, their dissolved concentrations need to be measured with high spatial and temporal resolution. To achieve this goal, we developed the Fast-Response Automated Gas Equilibrator (FaRAGE) for real-time in situ measurement of dissolved CH4 and CO2 concentrations at the water surface and in the water column. FaRAGE can achieve an exceptionally short response time (t(95%) = 12 s when including the response time of the gas analyzer) while retaining an equilibration ratio of 62.6% and a measurement accuracy of 0.5% for CH4. A similar performance was observed for dissolved CO2 (t(95%) = 10 s, equilibration ratio 67.1 %). An equilibration ratio as high as 91.8% can be reached at the cost of a slightly increased response time (16 s). The FaRAGE is capable of continuously measuring dissolved CO2 and CH4 concentrations in the nM-to-submM (10(-9)-10(-3) mol L-1) range with a detection limit of subnM (10(-10) mol L-1), when coupling with a cavity ring-down greenhouse gas analyzer (Picarro GasScouter). FaRAGE allows for the possibility of mapping dissolved concentration in a "quasi" three-dimensional manner in lakes and provides an inexpensive alternative to other commercial gas equilibrators. It is simple to operate and suitable for continuous monitoring with a strong tolerance for suspended particles. While the FaRAGE is developed for inland waters, it can be also applied to ocean waters by tuning the gas-water mixing ratio. The FaRAGE is easily adapted to suit other gas analyzers expanding the range of potential applications, including nitrous oxide and isotopic composition of the gases.
Y1  - 2020
U6  - https://doi.org/10.5194/hess-24-3871-2020
SN  - 1027-5606
SN  - 1607-7938
VL  - 24
IS  - 7
SP  - 3871
EP  - 3880
PB  - European Geosciences Union (EGU) ; Copernicus
CY  - Munich
ER  - 
TY  - JOUR
A1  - Lass, Sander
A1  - Gronau, Norbert
T1  - A factory operating system for extending existing factories to Industry 4.0
JF  - Computers in industry : an international, application oriented research journal
N2  - Cyber-physical systems (CPS) have shaped the discussion about Industry 4.0 (I4.0) for some time. To ensure the competitiveness of manufacturing enterprises the vision for the future figures out cyber-physical production systems (CPPS) as a core component of a modern factory. Adaptability and coping with complexity are (among others) potentials of this new generation of production management. The successful transformation of this theoretical construct into practical implementation can only take place with regard to the conditions characterizing the context of a factory. The subject of this contribution is a concept that takes up the brownfield character and describes a solution for extending existing (legacy) systems with CPS capabilities.
KW  - Factory operating system
KW  - CPPS
KW  - CPS
KW  - Decentralized production control
KW  - Industry 4.0
KW  - retrofit
Y1  - 2019
U6  - https://doi.org/10.1016/j.compind.2019.103128
SN  - 0166-3615
SN  - 1872-6194
VL  - 115
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Kaitoua, Abdulrahman
A1  - Rabl, Tilmann
A1  - Markl, Volker
T1  - A distributed data exchange engine for polystores
JF  - Information technology : methods and applications of informatics and information technology
JF  - Information technology : Methoden und innovative Anwendungen der Informatik und Informationstechnik
N2  - There is an increasing interest in fusing data from heterogeneous sources. Combining data sources increases the utility of existing datasets, generating new information and creating services of higher quality. A central issue in working with heterogeneous sources is data migration: In order to share and process data in different engines, resource intensive and complex movements and transformations between computing engines, services, and stores are necessary.
Muses is a distributed, high-performance data migration engine that is able to interconnect distributed data stores by forwarding, transforming, repartitioning, or broadcasting data among distributed engines' instances in a resource-, cost-, and performance-adaptive manner. As such, it performs seamless information sharing across all participating resources in a standard, modular manner. We show an overall improvement of 30 % for pipelining jobs across multiple engines, even when we count the overhead of Muses in the execution time. This performance gain implies that Muses can be used to optimise large pipelines that leverage multiple engines.
KW  - distributed systems
KW  - data migration
KW  - data transformation
KW  - big data
KW  - engine
KW  - data integration
Y1  - 2020
U6  - https://doi.org/10.1515/itit-2019-0037
SN  - 1611-2776
SN  - 2196-7032
VL  - 62
IS  - 3-4
SP  - 145
EP  - 156
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Al-Saedy, Ammar Jaffar Muhesin
A1  - Tarchanov, Nikolaj Nikolaevič
T1  - A degree theory for Lagrangian boundary value problems
JF  - Žurnal Sibirskogo Federalʹnogo Universiteta = Journal of Siberian Federal University; mathematics & physics
N2  - We study those nonlinear partial differential equations which appear as Euler-Lagrange equations of variational problems. On defining weak boundary values of solutions to such equations we initiate the theory of Lagrangian boundary value problems in spaces of appropriate smoothness. We also analyse if the concept of mapping degree of current importance applies to Lagrangian problems.
N2  - Мы изучаем те нелинейные уравнения с частными производными, которые возникают как уравнения Эйлера-Лагранжа вариационных задач. Определяя слабые граничные значения решений таких уравнений, мы инициируем теорию лагранжевых краевых задач в функциональных пространствах подходящей гладкости. Мы также анализируем, применяется ли современная концепция степени отображения к лагранжевым проблемам.
KW  - nonlinear equations
KW  - Lagrangian system
KW  - weak boundary values
KW  - quasilinear Fredholm operators
KW  - mapping degree
Y1  - 2020
U6  - https://doi.org/10.17516/1997-1397-2020-13-1-5-25
SN  - 1997-1397
SN  - 2313-6022
VL  - 13
IS  - 1
SP  - 5
EP  - 25
PB  - Sibirskij Federalʹnyj Universitet
CY  - Krasnojarsk
ER  - 
TY  - JOUR
A1  - Brill, Fabio Alexander
A1  - Passuni Pineda, Silvia
A1  - Espichan Cuya, Bruno
A1  - Kreibich, Heidi
T1  - A data-mining approach towards damage modelling for El Nino events in Peru
JF  - Geomatics, natural hazards and risk
N2  - Compound natural hazards likeEl Ninoevents cause high damage to society, which to manage requires reliable risk assessments. Damage modelling is a prerequisite for quantitative risk estimations, yet many procedures still rely on expert knowledge, and empirical studies investigating damage from compound natural hazards hardly exist. A nationwide building survey in Peru after theEl Ninoevent 2017 - which caused intense rainfall, ponding water, flash floods and landslides - enables us to apply data-mining methods for statistical groundwork, using explanatory features generated from remote sensing products and open data. We separate regions of different dominant characteristics through unsupervised clustering, and investigate feature importance rankings for classifying damage via supervised machine learning. Besides the expected effect of precipitation, the classification algorithms select the topographic wetness index as most important feature, especially in low elevation areas. The slope length and steepness factor ranks high for mountains and canyons. Partial dependence plots further hint at amplified vulnerability in rural areas. An example of an empirical damage probability map, developed with a random forest model, is provided to demonstrate the technical feasibility.
KW  - Natural hazard
KW  - damage model
KW  - residential buildings
KW  - data-mining
KW  - remote
KW  - sensing
KW  - open data
Y1  - 2020
U6  - https://doi.org/10.1080/19475705.2020.1818636
SN  - 1947-5705
SN  - 1947-5713
VL  - 11
IS  - 1
SP  - 1966
EP  - 1990
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Kratky, Nicole
A1  - Schröder-Abé, Michela
T1  - A court file analysis of child protection cases
BT  - what do children say?
JF  - Child & family social work
N2  - Children's participation in legal proceedings affecting them personally has been gaining importance. So far, a primary research concern has been how children experience their participation in court proceedings. However, little is known about the child's voice itself: Are children able to clearly express their wishes, and if so, what do they say in child protection cases? In this study, we extracted information about children's statements from court file data of 220 child protection cases in Germany. We found 182 children were asked about their wishes. The majority of the statements found came either from reports of the guardians ad litem or from judicial records of the child hearings. Using content analysis, three main aspects of the statements were extracted: wishes concerning main place of residence, wishes about whom to have or not contact with, and children granting decision-making authority to someone else. Children's main focus was on their parents, but others (e.g., relatives and foster care providers) were also mentioned. Intercoder agreement was substantial. Making sure that child hearings are as informative as possible is in the child's best interest. Therefore, the categories developed herein might help professionals to ask questions more precisely relevant to the child.
KW  - children's participation
KW  - child protection
KW  - child's voice
KW  - child
KW  - welfare
KW  - court files
KW  - family court
Y1  - 2020
U6  - https://doi.org/10.1111/cfs.12744
SN  - 1356-7500
SN  - 1365-2206
VL  - 25
IS  - S1
SP  - 169
EP  - 177
PB  - Wiley-Blackwell
CY  - Oxford
ER  -