TY - JOUR A1 - Krasnova, Hanna A1 - Veltri, Natasha F. A1 - Spengler, Klaus A1 - Günther, Oliver T1 - "Deal of the Day" Platforms what drives Consumer loyalty? JF - Business & information systems engineering : the international journal of Wirtschaftsinformatik N2 - "Deal of the Day" (DoD) platforms have quickly become popular by offering savings on local services, products and vacations. For merchants, these platforms represent a new marketing channel to advertise their products and services and attract new customers. DoD platform providers, however, struggle to maintaining a stable market share and profitability, because entry and switching costs are low. To sustain a competitive market position, DoD providers are looking for ways to build a loyal customer base. However, research examining the determinants of user loyalty in this novel context is scarce. To fill this gap, this study employs Grounded Theory methodology to develop a conceptual model of customer loyalty to a DoD provider. In the next step, qualitative insights are enriched and validated using quantitative data from a survey of 202 DoD users. The authors find that customer loyalty is in large part driven by monetary incentives, but can be eroded if impressions from merchant encounters are below expectations. In addition, enhancing the share of deals relevant for consumers, i.e. signal-to-noise ratio, and mitigating perceived risks of a transaction emerge as challenges. Beyond theoretical value, the results offer practical insights into how customer loyalty to a DoD provider can be promoted. KW - Deal of the Day KW - Loyalty KW - Grounded theory KW - Structural equation modeling Y1 - 2013 U6 - https://doi.org/10.1007/s12599-013-0268-2 SN - 1867-0202 VL - 5 IS - 3 SP - 165 EP - 177 PB - Springer CY - Heidelberg ER - TY - THES A1 - Wolfram, Jaqueline T1 - "Ich schreibe, solange ich lebe" : Schreiben über die Shoah - der Holocaustüberlebende und Autor Noah Klieger N2 - Der israelische Autor und Journalist Noah Klieger ist in der deutschsprachigen Forschung zur Holocaustliteratur, in deren Kontext theoretische Konzepte und Interpretationen zahlreicher Autoren (u.a. Ruth Klüger, Primo Levi) dieser Gattung vorliegen, bisher kaum beachtet worden. In der vorliegenden Arbeit steht seine 2010 erschienene Autobiographie „Zwölf Brötchen zum Frühstück“ im Zentrum. Innerhalb der Textanalyse wird der Frage nachgegangen, welche Bedeutung das Schreiben für Klieger hat und inwieweit seine als Reportage angelegte Autobiographie, die den sehr faktenbezogenen und dokumentarischen Stil des Journalisten widerspiegelt, den Rezipienten in der Interpretation lenkt und Authentizität erzeugt. Ausgehend von dieser Fragestellung werden für die Arbeit geführte Interviews mit Noah Klieger (oral history) einbezogen und der Erlebnisbericht „Ich habe den Todesengel überlebt“ von Eva Mozes-Kor, die das Konzept des Erlebnisberichtes mit all seinen Eigenschaften konstant bewahrt, zum Vergleich hinzugezogen. Im Fokus der Arbeit steht die Analyse der Autobiographie Kliegers, wobei auf das Genre Reportage, relevante Stilmittel, zentrale Begrifflichkeiten und Veröffentlichungskontexte sowie auf die Gedächtnistheorie von Maurice Halbwachs eingegangen werden. Abschließend wird die Thematik des Vergebens bei Klieger und Mozes-Kor erörtert. Die Forschungsergebnisse stellen den israelischen Holocaustüberlebenden Noah Klieger als Autor vor und verdeutlichen, dass die innerhalb der Gattung Holocaustliteratur gewählten Darstellungsweisen unterschiedliche Formen von Authentizität evozieren. N2 - Israeli author and journalist Noah Klieger has been ignored by German scientists of Holocaust literature though there are many theoretical concepts and interpretations of other writers such as Ruth Klüger and Primo Levi. In this paper we will focus on his autobiography published in 2010 named “Zwölf Brötchen zum Frühstück”. In the text analysis we will discuss what the act of writing means to Klieger and to what extent his autobiography reflects relation to facts, documentary pen and influences recipients. In accordance with this leading question we will integrate interviews with Noah Klieger (oral history) and a report from Eva Mozes-Kor titled “Ich habe den Todesengel überlebt”. This report constantly maintains the characteristics of a report. The centre of attention is the analysis of Noah Klieger’s autobiography, the characteristics of a report, rhetorical devices, defining key terminology, the context of publishing as well as Maurice Halbwach’s memory research theories. Finally, we discuss forgiving based on texts by Klieger and Mozes-Kor is discussed. The results of the research introduce Israeli holocaust survivor Noah Klieger as an author and clarify that within holocaust literature the different forms of expression evoke many different facets of authenticity. KW - Konzentrationslager Auschwitz KW - Holocaust KW - autobiographische Literatur KW - Überlebender KW - Erinnerungskultur KW - holocaust KW - holocaust in literature KW - Jewish KW - biography KW - concentration camp Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-67327 ER - TY - THES A1 - Koppermann, Ulrike T1 - "Indem wir die Dichtung zur Angelegenheit existentieller Entschlüsse der Dichter machen..." BT - Zu Engagement und Vergangenheitsverdrängung in Alfred Anderschs Roman "Die Rote" N2 - Von einer kritischen Analyse des Artikels "Deutsche Literatur in der Entscheidung" (1947) von Alfred Andersch ausgehend, fragt die Untersuchung nach dem Spannungsverhältnis von literarischem Engagement im Sinne Sartres und konzeptuellen Leerstellen in der Auseinandersetzung mit der deutschen NS-Vergangenheit, welches sich in dem programmatischen Aufsatz und Anderschs Roman "Die Rote" (1972) nachweisen lässt. KW - Alfred Andersch KW - Jean-Paul Sartre KW - Die Rote KW - Vergangenheitsverdrängung KW - deutsche Existentialismus-Rezeption Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-70485 ER - TY - JOUR A1 - Müller, Gesine T1 - "La litterature jaune" : Gustave d'Alaux und die frühen Zeugnisse haitianischer Literaturgeschichtsschreibung Y1 - 2013 SN - 978-3-7705-5407-2 ER - TY - JOUR A1 - Ette, Ottmar T1 - "Mobile mappings" y las literaturas sin residencia fija : Perspectivas de una poética del movimiento Y1 - 2013 SN - 978-3-938944-69-1 ER - TY - JOUR A1 - Dolya, Natalya A1 - Rojas, Oscar A1 - Kosmella, Sabine A1 - Tiersch, Brigitte A1 - Koetz, Joachim A1 - Kudaibergenov, Sarkyt T1 - "One-Pot" in situ frmation of Gold Nanoparticles within Poly(acrylamide) Hydrogels JF - Macromolecular chemistry and physics N2 - This paper focuses on two different strategies to incorporate gold nanoparticles (AuNPs) into the matrix of polyacrylamide (PAAm) hydrogels. Poly(ethyleneimine) (PEI) is used as both reducing and stabilizing agent for the formation of AuNPs. In addition, the influence of an ionic liquid (IL) (i.e., 1-ethyl-3-methylimidazolium ethylsulfate) on the stability of the nanoparticles and their immobilization in the hydrogel is investigated The results show that AuNPs surrounded by a shell containing PEI and IL, synthesized according to the one-pot approach, are much better immobilized within the PAAm hydrogel. Hereby, the IL is responsible for structural changes in the hydrogel as well as the improved stabilization and embedding of the AuNPs into the polymer gel matrix. KW - gold nanoparticles KW - immobilization KW - ionic liquids KW - poly(acrylamide) hydrogels Y1 - 2013 U6 - https://doi.org/10.1002/macp.201200727 SN - 1022-1352 VL - 214 IS - 10 SP - 1114 EP - 1121 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Schwarz, Anja T1 - "Parallel Societies" of the Past? - Articulations of citizenship's commemorative dimension in Berlin's cityscape JF - Space and Culture N2 - Historical narratives play an important role in constructing contemporary notions of citizenship. They are sites on which ideas of the nation are not only reaffirmed but also contested and reframed. In contemporary Germany, dominant narratives of the country's modern history habitually focus on the legacy of the Third Reich and tend to marginalize the country's rich and highly complex histories of immigration. The article addresses this commemorative void in relation to Berlin's urban landscape. It explores how the city's multilayered architecture provides locations for the articulation of marginal memoriesand hence sites of urban citizenshipthat are often denied to immigrant communities on a national scale. Through a detailed examination of a small celebration in 1965 that marked the anniversary of the founding of the modern Turkish republic, the article engages with the layers of history that coalesce around such sites in Berlin. KW - Berlin KW - commemorative acts of citizenship KW - migration KW - multidirectional memory Y1 - 2013 U6 - https://doi.org/10.1177/1206331213487051 SN - 1206-3312 VL - 16 IS - 3 SP - 261 EP - 273 PB - Sage Publ. CY - Thousand Oaks ER - TY - JOUR A1 - Peitsch, Helmut T1 - "Rec [...] bleibt [...] lieber bey dem stehen, wo Hr. Forster in seinem eigentlichen Fache ist" : Forsters Reisebeschreibungen und Übersetzungen in der Allgemeinen deutschen Bibliothek Y1 - 2013 SN - 978-3-89971-909-3 ER - TY - BOOK A1 - Engel, Felix T1 - "Revoluzzer" oder "Leisetretter?" : der Weg zum Theologentag von Jüterborg 1548 Y1 - 2013 SN - 978-3-00-043185-2 PB - Kulturquartier Mönchenkloster CY - Jüterbog ER - TY - JOUR A1 - Fröhlich, Paul A1 - Kranz, Alexander T1 - "Ämterchaos" in der Wehrmachtbürokratie? Das Allgemeine Heeresamt, das Wehrwirtschafts- und Rüstungsamt und die deutsche Rüstungspolitik 1938 - 1940 Y1 - 2013 SN - 978-3-506-77657-0 ER - TY - JOUR A1 - Kleinpeter, Erich A1 - Koch, Andreas T1 - (Anti)aromaticity of dehydroannulenes of various ring size proved by the ring current effect in H-1 NMR spectra JF - Tetrahedron N2 - The spatial magnetic properties (Through-Space NMR Shieldings-TSNMRS) of already synthesized dehydro[n]annulenes of various ring size (from C-12 to C-20) have been computed, visualized as Isochemical Shielding Surfaces (ICSS) of various size and direction, and were examined subject to present (anti)aromaticity. For this purpose the thus quantified ring current effect of the macro cycles on proximate protons in proton NMR spectra was employed. KW - Dehydro[n]annulenes KW - (Anti)aromaticity KW - TSNMRS KW - H-1 NMR spectroscopy KW - Anisotropic effect KW - Theoretical calculations KW - ICSS Y1 - 2013 U6 - https://doi.org/10.1016/j.tet.2012.12.019 SN - 0040-4020 VL - 69 IS - 5 SP - 1481 EP - 1488 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Zimmermann, Andreas T1 - (Internationale) Strafverfolgung von Menschenrechtsverbrechen versus Friedenswahrung Y1 - 2013 SN - 978- 3-428-13933-0 ER - TY - THES A1 - Bucher, Leon T1 - (Re-)Kommunalisierung der Energieversorgung in Deutschland und den USA T2 - Forum Jurdicicum Y1 - 2013 SN - 978-3-86523-221-2 VL - 30 PB - Schüling CY - Münster ER - TY - THES A1 - Kneis, Philipp T1 - (S)aged by culture : Representations of old age in american indian literature and culture Y1 - 2013 SN - 978-3-631-63853-8 PB - Peter Lang Edition CY - Frankfurt am Main, New York ER - TY - JOUR A1 - Shainyan, Bagrat A. A1 - Kirpichenko, Svetlana V. A1 - Kleinpeter, Erich A1 - Shlykov, Sergey A. A1 - Osadchiy, Dmitriy Yu A1 - Chipanina, Nina N. A1 - Oznobikhina, Larisa P. T1 - 1,3-Dimethy1-3-silapiperidine - synthesis, molecular structure, and conformational analysis by gas-phase electron diffraction, low temperature NMR, IR and Raman Spectroscopy, and quantum chemical calculations JF - The journal of organic chemistry N2 - The first Si-H-containing azasilaheterocycle, 1,3-dimethyl-3-silapiperidine 1, was synthesized, and its molecular structure and conformational properties were studied by gas-phase electron diffraction (GED), low temperature NMR, IR and Raman spectroscopy and quantum chemical calculations. The compound exists as a mixture of two conformers possessing the chair conformation with the equatorial NMe group and differing by axial or equatorial position of the SiMe group. In the gas phase, the SiMeax conformer predominates (GED: ax/eq = 65(7):35(7)%,Delta G = 0.36(18) kcal/mol; IR: ax/eq = 62(5):38(5)%,Delta G = 0.16(7) kcal/mol). In solution, at 143 k the SiMeeq conformer predominates' in the frozen equilibrium (NMR: ax/eq = 31.5(1.5):68.5(1.5)%, Delta G = -0.22(2) kcal/mol). Thermodynamic parameters of the ring inversion are determined (Delta G(double dagger) = 8.9-9.0 kcal/mol, Delta H-double dagger = 9.6 kcal/mol, Delta S-double dagger = 2.1 eu). High-level quantum chemical calculations :(MP2, G2, CCSD(T)) nicely reproduce the experimental geometry and the predominance of the axial conformer in the gas phase. Y1 - 2013 U6 - https://doi.org/10.1021/jo400289g SN - 0022-3263 VL - 78 IS - 8 SP - 3939 EP - 3947 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Calo, Camilla A1 - Henne, Paul D. A1 - Eugster, Patricia A1 - van Leeuwen, Jacqueline A1 - Gilli, Adrian A1 - Hamann, Yvonne A1 - La Mantia, Tommaso A1 - Pasta, Salvatore A1 - Vescovi, Elisa A1 - Tinner, Willy T1 - 1200 years of decadal-scale variability of mediterranean vegetation and climate at Pantelleria Island, Italy JF - The Holocene : an interdisciplinary journal focusing on recent environmental change N2 - A new sedimentary sequence from Lago di Venere on Pantelleria Island, located in the Strait of Sicily between Tunisia and Sicily was recovered. The lake is located in the coastal infra-Mediterranean vegetation belt at 2 m a.s.l. Pollen, charcoal and sedimentological analyses are used to explore linkages among vegetation, fire and climate at a decadal scale over the past 1200 years. A dry period from ad 800 to 1000 that corresponds to the Medieval Warm Period' (WMP) is inferred from sedimentological analysis. The high content of carbonate recorded in this period suggests a dry phase, when the ratio of evaporation/precipitation was high. During this period the island was dominated by thermophilous and drought-tolerant taxa, such as Quercus ilex, Olea, Pistacia and Juniperus. A marked shift in the sediment properties is recorded at ad 1000, when carbonate content became very low suggesting wetter conditions until ad 1850-1900. Broadly, this period coincides with the Little Ice Age' (LIA), which was characterized by wetter and colder conditions in Europe. During this time rather mesic conifers (i.e. Pinus pinaster), shrubs and herbs (e.g. Erica arborea and Selaginella denticulata) expanded, whereas more drought-adapted species (e.g. Q. ilex) declined. Charcoal data suggest enhanced fire activity during the LIA probably as a consequence of anthropogenic burning and/or more flammable fuel (e.g. resinous Pinus biomass). The last century was characterized by a shift to high carbonate content, indicating a change towards drier conditions, and re-expansion of Q. ilex and Olea. The post-LIA warming is in agreement with historical documents and meteorological time series. Vegetation dynamics were co-determined by agricultural activities on the island. Anthropogenic indicators (e.g. Cerealia-type, Sporormiella) reveal the importance of crops and grazing on the island. Our pollen data suggest that extensive logging caused the local extinction of deciduous Quercus pubescens around ad1750. KW - central Mediterranean KW - fire history KW - "Little Ice Age' (LIA) KW - "Medieval Warm Period' (MWP) KW - Pinus pinaster KW - Quercus ilex KW - Quercus pubescens KW - vegetation history Y1 - 2013 U6 - https://doi.org/10.1177/0959683613493935 SN - 0959-6836 SN - 1477-0911 VL - 23 IS - 10 SP - 1477 EP - 1486 PB - Sage Publ. CY - London ER - TY - JOUR A1 - Schmidt, Bernd A1 - Riemer, Martin A1 - Karras, Manfred T1 - 2,2 '-Biphenols via protecting group-free thermal or microwave-accelerated suzuki-miyaura coupling in water JF - The journal of organic chemistry N2 - User-friendly protocols for the protecting group-free synthesis of 2,2'-biphenols via Suzuki-Miyaura coupling of o-halophenols and o-boronophenol are presented. The reactions proceed in water in the presence of simple additives such as K2CO3, KOH, KF, or TBAF and with commercially available Pd/C as precatalyst. Expensive or laboriously synthesized ligands or other additives are not required. In the case of bromophenols, efficient rate acceleration and short reaction times were accomplished by microwave irradiation. Y1 - 2013 U6 - https://doi.org/10.1021/jo401398n SN - 0022-3263 VL - 78 IS - 17 SP - 8680 EP - 8688 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Dzambaski, Zdravko A1 - Markovic, Rade A1 - Kleinpeter, Erich A1 - Baranac-Stojanovic, Marija T1 - 2-Alkylidene-4-oxothiazolidine S-oxides - synthesis and stereochemistry JF - Tetrahedron N2 - A series of 5-unsubstituted and 5-substituted 2-alkylidene-4-oxothiazolidine-S-oxides were synthesized by the sulfur-oxidation with m-CPBA. The stereochemistry of 5-substituted sulfoxides was determined by means of NMR spectroscopy and DFT theoretical calculations. It was found that the thermodynamically less stable anti-isomer was initially formed in the course of the oxidation, but it underwent epimerization to the mixture enriched in the more stable syn-isomer, during the work-up process. The higher stability of syn-isomers is ascribed to the stronger hyperconjugative sigma(C-H)->sigma*(S-O) interaction versus the weaker sigma(C-C)->sigma*(S-O) delocalization in their anti-counterparts and to the existence of intramolecular 1,5-CH center dot center dot center dot C hydrogen bonds. KW - 2-Alkylidene-4-oxothiazolidine KW - Sulfoxide KW - Diastereoselectivity KW - Density functional calculations KW - CH center dot center dot center dot O hydrogen bonds Y1 - 2013 U6 - https://doi.org/10.1016/j.tet.2013.05.087 SN - 0040-4020 VL - 69 IS - 31 SP - 6436 EP - 6447 PB - Elsevier CY - Oxford ER - TY - THES A1 - Amour, Frédéric T1 - 3-D modeling of shallow-water carbonate systems : a scale-dependent approach based on quantitative outcrop studies T1 - 3-D Modellierung von Flachwasser-Karbonat-Sytemen : eine skalenabhängige Herangehensweise basierend auf quantitativen Aufschlussstudien N2 - The study of outcrop modeling is located at the interface between two fields of expertise, Sedimentology and Computing Geoscience, which respectively investigates and simulates geological heterogeneity observed in the sedimentary record. During the last past years, modeling tools and techniques were constantly improved. In parallel, the study of Phanerozoic carbonate deposits emphasized the common occurrence of a random facies distribution along single depositional domain. Although both fields of expertise are intrinsically linked during outcrop simulation, their respective advances have not been combined in literature to enhance carbonate modeling studies. The present study re-examines the modeling strategy adapted to the simulation of shallow-water carbonate systems, based on a close relationship between field sedimentology and modeling capabilities. In the present study, the evaluation of three commonly used algorithms Truncated Gaussian Simulation (TGSim), Sequential Indicator Simulation (SISim), and Indicator Kriging (IK), were performed for the first time using visual and quantitative comparisons on an ideally suited carbonate outcrop. The results show that the heterogeneity of carbonate rocks cannot be fully simulated using one single algorithm. The operating mode of each algorithm involves capabilities as well as drawbacks that are not capable to match all field observations carried out across the modeling area. Two end members in the spectrum of carbonate depositional settings, a low-angle Jurassic ramp (High Atlas, Morocco) and a Triassic isolated platform (Dolomites, Italy), were investigated to obtain a complete overview of the geological heterogeneity in shallow-water carbonate systems. Field sedimentology and statistical analysis performed on the type, morphology, distribution, and association of carbonate bodies and combined with palaeodepositional reconstructions, emphasize similar results. At the basin scale (x 1 km), facies association, composed of facies recording similar depositional conditions, displays linear and ordered transitions between depositional domains. Contrarily, at the bedding scale (x 0.1 km), individual lithofacies type shows a mosaic-like distribution consisting of an arrangement of spatially independent lithofacies bodies along the depositional profile. The increase of spatial disorder from the basin to bedding scale results from the influence of autocyclic factors on the transport and deposition of carbonate sediments. Scale-dependent types of carbonate heterogeneity are linked with the evaluation of algorithms in order to establish a modeling strategy that considers both the sedimentary characteristics of the outcrop and the modeling capabilities. A surface-based modeling approach was used to model depositional sequences. Facies associations were populated using TGSim to preserve ordered trends between depositional domains. At the lithofacies scale, a fully stochastic approach with SISim was applied to simulate a mosaic-like lithofacies distribution. This new workflow is designed to improve the simulation of carbonate rocks, based on the modeling of each scale of heterogeneity individually. Contrarily to simulation methods applied in literature, the present study considers that the use of one single simulation technique is unlikely to correctly model the natural patterns and variability of carbonate rocks. The implementation of different techniques customized for each level of the stratigraphic hierarchy provides the essential computing flexibility to model carbonate systems. Closer feedback between advances carried out in the field of Sedimentology and Computing Geoscience should be promoted during future outcrop simulations for the enhancement of 3-D geological models. N2 - Das Modellieren von geologischen Aufschlüssen liegt der Schnittstelle zwischen zwei geo-logischen Teildisziplinen, der Sedimentologie und der geologischen Modellierung. Hierbei werden geologische Heterogenitäten untersucht und simuliert, welche im Aufschluss beobachtet wurden. Während der letzten Jahre haben sich die Werkzeuge und die Technik der Modellierung stetig weiter-entwickelt. Parallel dazu hat die Untersuchung der phanerozoischen Karbonatablagerungen ihren Fokus auf gemeinsamen Vorkommen von zufälligen Faziesverteilungen in beiden Ablagerungs-gebieten. Obwohl beide Teildisziplinen durch die Aufschlussmodellierung eigentlich verbunden sind, wurden ihre jeweiligen Vorteile in der Literatur nicht miteinander verbunden, um so eine Verbesserung ähnlicher Studien zu erreichen. Die vorliegende Studie überprüft erneut die Modellierungsstrategie, angepasst an die Simulation von Flachwasser-Karbonat-Systemen und basierend auf einer engen Beziehung zwischen Sedimentologie und Modellierung. Die vorliegende Arbeit behandelt erstmals die Evaluierung der drei am häufigsten verwendeten Algorithmen „Truncated Gaussian Simulation (TGSim)“, „Sequential Indicator Simulation (SISim)“ und „Indicator Kriging (IK)“, um sie visuell und quantitativ mit dem entsprechenden Aufschluss zu vergleichen. Die Ergebnisse zeigen, dass die Heterogenität von Karbonatgesteinen nicht komplett mit nur einem Algorithmus simuliert werden kann. Die Eigenschaften jedes einzelnen Algorithmus beinhalten Vor- und Nachteile, sodass kein Algorithmus alle Beobachtungen aus dem Aufschluss widerspiegelt. Die zwei Endglieder im Spektrum der Ablagerungsbedingungen von Karbonaten, eine flachwinklige, jurassische Karbonat-Rampe (Hoher Atlas, Marokko) und eine isolierte, triassische Plattform (Dolomiten, Italien), wurden untersucht, um einen kompletten Überblick über die verschiedenen Heterogenitäten in Flachwasser-Karbonat- Systemen zu erhalten. Sedimentologische und statistische Analysen wurden für die verschiedenen Typen, Morphologien, Verteilungen und Assoziationen von Karbonatablagerungen durchgeführt und mit paläogeografischen Rekonstruktionen kombiniert und zeigen ähnliche Ergebnisse. Im Beckenmaßstab zeigen die Faziesassoziationen, bestehend aus Fazieszonen mit ähnlichen Ablagerungsbedingungen, einen linearen und kontinuierlichen Übergang zwischen den einzelnen Ablagerungsbereichen. Im Gegensatz dazu zeigt für einzelne Lithofaziestypen im Maßstab einzelner Schichten eine mosaikartige Verteilung, bestehend aus einer Anordnung räumlich unabhängiger Lithofazieszonen entlang des Ablagerungsprofils. Das Ansteigen der räumlichen Unordnung von der beckenweiten Ablagerung zur Ablagerung einzelner Schichten resultiert aus dem Einfluss autozyklischer Faktoren bei der Ablagerung von Karbonaten. Die Skalenabhängigkeit von Karbonat-Heterogenität ist mit der Auswertung der Algorithmen verknüpft um eine Modellierungsstrategie zu etablieren, welche sowohl die sedimentären Charakteristiken des Aufschlusses als auch die Modellierfähigkeit berücksichtigt. Für die Modellierung der Ablagerungssequenzen wurde ein flächenbasierter Ansatz verwendet. Die Faziesassoziationen wurden durch die Benutzung des TGSim-Algorithmus simuliert, um die regulären Trends zwischen den einzelnen Ablagerungsgebieten zu erhalten. Im Bereich der verschiedenen Lithofazien wurde mit dem SISim-Algorithmus, ein voll stochastischer Ansatz angewendet, um die mosaikartige Verteilung der Lithofazies-Typen zu simulieren. Dieser neue Arbeitsablauf wurde konzipiert, um die Simulierung von Karbonaten auf Basis der einzelnen Heterogenitäten in verschiedenen Größenordnungen zu verbessern. Im Gegensatz zu den in der Literatur angewendeten Simulationsmethoden berücksichtigt diese Studie, dass eine einzelne Modellierungstechnik die natürlichen Ablagerungsmuster und Variabilität von Karbonaten wahrscheinlich nicht korrekt abbildet. Die Einführung verschiedener Techniken, angepasst auf die verschiedenen Ebenen der stratigrafischen Hierarchie, liefert die notwendige Flexibilität um Karbonatsysteme korrekt zu modellieren. Eine enge Verknüpfung zwischen den Fortschritten auf dem Gebieten der Sedimentologie und dem Gebiet der modellierenden Geowissenschaften sollte weiterhin bestehen, um auch zukünftig bei der Simulation von geologischen Gelände-Aufschlüssen eine Verbesserung der 3-D-Modellierung zu erreichen. KW - Karbonat KW - 3-D Modellierung KW - Aufschluss-Modellierung KW - Quantitative Daten KW - Skala KW - Stochastischer Algorithmus KW - Carbonate KW - 3-D outcrop modeling KW - quantitative data KW - scale KW - stochastic algorithms Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-66621 ER - TY - JOUR A1 - Mutai, Peggoty A1 - Heydenreich, Matthias A1 - Thoithi, Grace A1 - Mugumbate, Grace A1 - Chibale, Kelly A1 - Yenesew, Abiy T1 - 3-Hydroxyisoflavanones from the stem bark of dalbergia melanoxylon - isolation, antimycobacterial evaluation and molecular docking studies JF - Phytochemistry letters N2 - Two new 3-hydroxyisoflavanones, (S)-3,4',5-trihydroxy-2',7-dimethoxy-3'-prenylisoflavanone (trivial name kenusanone F 7-methyl ether) and (S)-3,5-dihydroxy-2',7-dimethoxy-2 '',2 ''-dimethylpyrano[5 '',6 '':3',4']isoflavanone (trivial name sophoronol-7-methyl ether) along with two known compounds (dalbergin and formononetin) were isolated from the stem bark of Dalbergia melanoxylon. The structures were elucidated using spectroscopic techniques. Kenusanone F 7-methyl ether showed activity against Mycobacterium tuberculosis, whereas both of the new compounds were inactive against the malaria parasite Plasmodium falciparum at 10 mu g/ml. Docking studies showed that the new compounds kenusanone F 7-methyl ether and sophoronol-7-methyl ether have high affinity for the M. tuberculosis drug target INHA. KW - Dalbergia melanoxylon KW - 3-Hydroxyisoflavanone KW - Kenusanone F 7-methyl ether KW - Sophoronol-7-methyl ether KW - Mycobacterium tuberculosis KW - Docking Y1 - 2013 U6 - https://doi.org/10.1016/j.phytol.2013.08.018 SN - 1874-3900 SN - 1876-7486 VL - 6 IS - 4 SP - 671 EP - 675 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dölling, Irene T1 - 30 Years of feminist studies how do we deal with the feminist Heritage? JF - Feministische Studien : Zeitschrift für interdisziplinäre Frauen- und Geschlechterforschung Y1 - 2013 SN - 0723-5186 VL - 31 IS - 1 SP - 29 EP - 34 PB - Lucius & Lucius CY - Stuttgart ER - TY - JOUR A1 - Kaiser, Björn Onno A1 - Cacace, Mauro A1 - Scheck-Wenderoth, Magdalena T1 - 3D coupled fluid and heat transport simulations of the Northeast German Basin and their sensitivity to the spatial discretization - different sensitivities for different mechanisms of heat transport JF - Environmental earth sciences N2 - Based on a numerical model of the Northeast German Basin (NEGB), we investigate the sensitivity of the calculated thermal field as resulting from heat conduction, forced and free convection in response to consecutive horizontal and vertical mesh refinements. Our results suggest that computational findings are more sensitive to consecutive horizontal mesh refinements than to changes in the vertical resolution. In addition, the degree of mesh sensitivity depends strongly on the type of the process being investigated, whether heat conduction, forced convection or free thermal convection represents the active heat driver. In this regard, heat conduction exhibits to be relative robust to imposed changes in the spatial discretization. A systematic mesh sensitivity is observed in areas where forced convection promotes an effective role in shorten the background conductive thermal field. In contrast, free thermal convection is to be regarded as the most sensitive heat transport process as demonstrated by non-systematic changes in the temperature field with respect to imposed changes in the model resolution. KW - Mesh convergence KW - Conduction KW - Advection KW - Convection KW - Thermal field KW - Northeast German Basin Y1 - 2013 U6 - https://doi.org/10.1007/s12665-013-2249-7 SN - 1866-6280 SN - 1866-6299 VL - 70 IS - 8 SP - 3643 EP - 3659 PB - Springer CY - New York ER - TY - THES A1 - Holz, Christian T1 - 3D from 2D touch T1 - 3D von 2D-Berührungen N2 - While interaction with computers used to be dominated by mice and keyboards, new types of sensors now allow users to interact through touch, speech, or using their whole body in 3D space. These new interaction modalities are often referred to as "natural user interfaces" or "NUIs." While 2D NUIs have experienced major success on billions of mobile touch devices sold, 3D NUI systems have so far been unable to deliver a mobile form factor, mainly due to their use of cameras. The fact that cameras require a certain distance from the capture volume has prevented 3D NUI systems from reaching the flat form factor mobile users expect. In this dissertation, we address this issue by sensing 3D input using flat 2D sensors. The systems we present observe the input from 3D objects as 2D imprints upon physical contact. By sampling these imprints at very high resolutions, we obtain the objects' textures. In some cases, a texture uniquely identifies a biometric feature, such as the user's fingerprint. In other cases, an imprint stems from the user's clothing, such as when walking on multitouch floors. By analyzing from which part of the 3D object the 2D imprint results, we reconstruct the object's pose in 3D space. While our main contribution is a general approach to sensing 3D input on 2D sensors upon physical contact, we also demonstrate three applications of our approach. (1) We present high-accuracy touch devices that allow users to reliably touch targets that are a third of the size of those on current touch devices. We show that different users and 3D finger poses systematically affect touch sensing, which current devices perceive as random input noise. We introduce a model for touch that compensates for this systematic effect by deriving the 3D finger pose and the user's identity from each touch imprint. We then investigate this systematic effect in detail and explore how users conceptually touch targets. Our findings indicate that users aim by aligning visual features of their fingers with the target. We present a visual model for touch input that eliminates virtually all systematic effects on touch accuracy. (2) From each touch, we identify users biometrically by analyzing their fingerprints. Our prototype Fiberio integrates fingerprint scanning and a display into the same flat surface, solving a long-standing problem in human-computer interaction: secure authentication on touchscreens. Sensing 3D input and authenticating users upon touch allows Fiberio to implement a variety of applications that traditionally require the bulky setups of current 3D NUI systems. (3) To demonstrate the versatility of 3D reconstruction on larger touch surfaces, we present a high-resolution pressure-sensitive floor that resolves the texture of objects upon touch. Using the same principles as before, our system GravitySpace analyzes all imprints and identifies users based on their shoe soles, detects furniture, and enables accurate touch input using feet. By classifying all imprints, GravitySpace detects the users' body parts that are in contact with the floor and then reconstructs their 3D body poses using inverse kinematics. GravitySpace thus enables a range of applications for future 3D NUI systems based on a flat sensor, such as smart rooms in future homes. We conclude this dissertation by projecting into the future of mobile devices. Focusing on the mobility aspect of our work, we explore how NUI devices may one day augment users directly in the form of implanted devices. N2 - Die Interaktion mit Computern war in den letzten vierzig Jahren stark von Tastatur und Maus geprägt. Neue Arten von Sensoren ermöglichen Computern nun, Eingaben durch Berührungs-, Sprach- oder 3D-Gestensensoren zu erkennen. Solch neuartige Formen der Interaktion werden häufig unter dem Begriff "natürliche Benutzungsschnittstellen" bzw. "NUIs" (englisch natural user interfaces) zusammengefasst. 2D-NUIs ist vor allem auf Mobilgeräten ein Durchbruch gelungen; über eine Milliarde solcher Geräte lassen sich durch Berührungseingaben bedienen. 3D-NUIs haben sich jedoch bisher nicht auf mobilen Plattformen durchsetzen können, da sie Nutzereingaben vorrangig mit Kameras aufzeichnen. Da Kameras Bilder jedoch erst ab einem gewissen Abstand auflösen können, eignen sie sich nicht als Sensor in einer mobilen Plattform. In dieser Arbeit lösen wir dieses Problem mit Hilfe von 2D-Sensoren, von deren Eingaben wir 3D-Informationen rekonstruieren. Unsere Prototypen zeichnen dabei die 2D-Abdrücke der Objekte, die den Sensor berühren, mit hoher Auflösung auf. Aus diesen Abdrücken leiten sie dann die Textur der Objekte ab. Anhand der Stelle der Objektoberfläche, die den Sensor berührt, rekonstruieren unsere Prototypen schließlich die 3D-Ausrichtung des jeweiligen Objektes. Neben unserem Hauptbeitrag der 3D-Rekonstruktion stellen wir drei Anwendungen unserer Methode vor. (1) Wir präsentieren Geräte, die Berührungseingaben dreimal genauer als existierende Geräte messen und damit Nutzern ermöglichen, dreimal kleinere Ziele zuverlässig mit dem Finger auszuwählen. Wir zeigen dabei, dass sowohl die Haltung des Fingers als auch der Benutzer selbst einen systematischen Einfluss auf die vom Sensor gemessene Position ausübt. Da existierende Geräte weder die Haltung des Fingers noch den Benutzer erkennen, nehmen sie solche Variationen als Eingabeungenauigkeit wahr. Wir stellen ein Modell für Berührungseingabe vor, das diese beiden Faktoren integriert, um damit die gemessenen Eingabepositionen zu präzisieren. Anschließend untersuchen wir, welches mentale Modell Nutzer beim Berühren kleiner Ziele mit dem Finger anwenden. Unsere Ergebnisse deuten auf ein visuelles Modell hin, demzufolge Benutzer Merkmale auf der Oberfläche ihres Fingers an einem Ziel ausrichten. Bei der Analyse von Berührungseingaben mit diesem Modell verschwinden nahezu alle zuvor von uns beobachteten systematischen Effekte. (2) Unsere Prototypen identifizieren Nutzer anhand der biometrischen Merkmale von Fingerabdrücken. Unser Prototyp Fiberio integriert dabei einen Fingerabdruckscanner und einen Bildschirm in die selbe Oberfläche und löst somit das seit Langem bestehende Problem der sicheren Authentifizierung auf Berührungsbildschirmen. Gemeinsam mit der 3D-Rekonstruktion von Eingaben ermöglicht diese Fähigkeit Fiberio, eine Reihe von Anwendungen zu implementieren, die bisher den sperrigen Aufbau aktueller 3D-NUI-Systeme voraussetzten. (3) Um die Flexibilität unserer Methode zu zeigen, implementieren wir sie auf einem großen, berührungsempfindlichen Fußboden, der Objekttexturen bei der Eingabe ebenfalls mit hoher Auflösung aufzeichnet. Ähnlich wie zuvor analysiert unser System GravitySpace diese Abdrücke, um Nutzer anhand ihrer Schuhsolen zu identifizieren, Möbelstücke auf dem Boden zu erkennen und Nutzern präzise Eingaben mittels ihrer Schuhe zu ermöglichen. Indem GravitySpace alle Abdrücke klassifiziert, erkennt das System die Körperteile der Benutzer, die sich in Kontakt mit dem Boden befinden. Aus der Anordnung dieser Kontakte schließt GravitySpace dann auf die Körperhaltungen aller Benutzer in 3D. GravitySpace hat daher das Potenzial, Anwendungen für zukünftige 3D-NUI-Systeme auf einer flachen Oberfläche zu implementieren, wie zum Beispiel in zukünftigen intelligenten Wohnungen. Wie schließen diese Arbeit mit einem Ausblick auf zukünftige interaktive Geräte. Dabei konzentrieren wir uns auf den Mobilitätsaspekt aktueller Entwicklungen und beleuchten, wie zukünftige mobile NUI-Geräte Nutzer in Form implantierter Geräte direkt unterstützen können. KW - HCI KW - Berührungseingaben KW - Eingabegenauigkeit KW - Modell KW - Mobilgeräte KW - HCI KW - touch input KW - input accuracy KW - model KW - mobile devices Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-67796 ER - TY - JOUR A1 - Ruzanski, Christian A1 - Smirnova, Julia A1 - Rejzek, Martin A1 - Cockburn, Darrell A1 - Pedersen, Henriette L. A1 - Pike, Marilyn A1 - Willats, William G. T. A1 - Svensson, Birte A1 - Steup, Martin A1 - Ebenhöh, Oliver A1 - Smith, Alison M. A1 - Field, Robert A. T1 - A bacterial glucanotransferase can replace the complex maltose metabolism required for starch to sucrose conversion in leaves at night JF - The journal of biological chemistry N2 - Controlled conversion of leaf starch to sucrose at night is essential for the normal growth of Arabidopsis. The conversion involves the cytosolic metabolism of maltose to hexose phosphates via an unusual, multidomain protein with 4-glucanotransferase activity, DPE2, believed to transfer glucosyl moieties to a complex heteroglycan prior to their conversion to hexose phosphate via a cytosolic phosphorylase. The significance of this complex pathway is unclear; conversion of maltose to hexose phosphate in bacteria proceeds via a more typical 4-glucanotransferase that does not require a heteroglycan acceptor. It has recently been suggested that DPE2 generates a heterogeneous series of terminal glucan chains on the heteroglycan that acts as a glucosyl buffer to ensure a constant rate of sucrose synthesis in the leaf at night. Alternatively, DPE2 and/or the heteroglycan may have specific properties important for their function in the plant. To distinguish between these ideas, we compared the properties of DPE2 with those of the Escherichia coli glucanotransferase MalQ. We found that MalQ cannot use the plant heteroglycan as an acceptor for glucosyl transfer. However, experimental and modeling approaches suggested that it can potentially generate a glucosyl buffer between maltose and hexose phosphate because, unlike DPE2, it can generate polydisperse malto-oligosaccharides from maltose. Consistent with this suggestion, MalQ is capable of restoring an essentially wild-type phenotype when expressed in mutant Arabidopsis plants lacking DPE2. In light of these findings, we discuss the possible evolutionary origins of the complex DPE2-heteroglycan pathway. KW - Carbohydrate Metabolism KW - Computer Modeling KW - Metabolic Regulation KW - Oligosaccharide KW - Plant Biochemistry KW - Glucanotransferase KW - Leaf Cell KW - Maltose Metabolism KW - Starch Degradation Y1 - 2013 U6 - https://doi.org/10.1074/jbc.M113.497867 SN - 0021-9258 SN - 1083-351X VL - 288 IS - 40 SP - 28581 EP - 28598 PB - American Society for Biochemistry and Molecular Biology CY - Bethesda ER - TY - JOUR A1 - Theves, Matthias A1 - Taktikos, Johannes A1 - Zaburdaev, Vasily A1 - Stark, Holger A1 - Beta, Carsten T1 - A bacterial swimmer with two alternating speeds of propagation JF - Biophysical journal N2 - We recorded large data sets of swimming trajectories of the soil bacterium Pseudomonas putida. Like other prokaryotic swimmers, P. putida exhibits a motion pattern dominated by persistent runs that are interrupted by turning events. An in-depth analysis of their swimming trajectories revealed that the majority of the turning events is characterized by an angle of phi(1) = 180 degrees (reversals). To a lesser extent, turning angles of phi(2 Sigma Sigma Sigma Sigma) = 00 are also found. Remarkably, we observed that, upon a reversal, the swimming speed changes by a factor of two on average a prominent feature of the motion pattern that, to our knowledge, has not been reported before. A theoretical model, based on the experimental values for the average run time and the rotational diffusion, recovers the mean-square displacement of P. putida if the two distinct swimming speeds are taken into account. Compared to a swimmer that moves with a constant intermediate speed, the mean-square displacement is strongly enhanced. We furthermore observed a negative dip in the directional autocorrelation at intermediate times, a feature that is only recovered in an extended model, where the nonexponential shape of the run-time distribution is taken into account. Y1 - 2013 U6 - https://doi.org/10.1016/j.bpj.2013.08.047 SN - 0006-3495 SN - 1542-0086 VL - 105 IS - 8 SP - 1915 EP - 1924 PB - Cell Press CY - Cambridge ER - TY - GEN A1 - Gschwind, Yves J. A1 - Kressig, Reto W. A1 - Lacroix, Andre A1 - Mühlbauer, Thomas A1 - Pfenninger, Barbara A1 - Granacher, Urs T1 - A best practice fall prevention exercise program to improve balance, strength/power, and psychosocial health in older adults BT - study protocol for a randomized controlled trial T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - Background: With increasing age neuromuscular deficits (e.g., sarcopenia) may result in impaired physical performance and an increased risk for falls. Prominent intrinsic fall-risk factors are age-related decreases in balance and strength / power performance as well as cognitive decline. Additional studies are needed to develop specifically tailored exercise programs for older adults that can easily be implemented into clinical practice. Thus, the objective of the present trial is to assess the effects of a fall prevention program that was developed by an interdisciplinary expert panel on measures of balance, strength / power, body composition, cognition, psychosocial well-being, and falls self-efficacy in healthy older adults. Additionally, the time-related effects of detraining are tested. Methods/Design: Healthy old people (n = 54) between the age of 65 to 80 years will participate in this trial. The testing protocol comprises tests for the assessment of static / dynamic steady-state balance (i.e., Sharpened Romberg Test, instrumented gait analysis), proactive balance (i.e., Functional Reach Test; Timed Up and Go Test), reactive balance (i.e., perturbation test during bipedal stance; Push and Release Test), strength (i.e., hand grip strength test; Chair Stand Test), and power (i.e., Stair Climb Power Test; countermovement jump). Further, body composition will be analysed using a bioelectrical impedance analysis system. In addition, questionnaires for the assessment of psychosocial (i.e., World Health Organisation Quality of Life Assessment-Bref), cognitive (i.e., Mini Mental State Examination), and fall risk determinants (i.e., Fall Efficacy Scale -International) will be included in the study protocol. Participants will be randomized into two intervention groups or the control / waiting group. After baseline measures, participants in the intervention groups will conduct a 12-week balance and strength / power exercise intervention 3 times per week, with each training session lasting 30 min. (actual training time). One intervention group will complete an extensive supervised training program, while the other intervention group will complete a short version (` 3 times 3') that is home-based and controlled by weekly phone calls. Post-tests will be conducted right after the intervention period. Additionally, detraining effects will be measured 12 weeks after program cessation. The control group / waiting group will not participate in any specific intervention during the experimental period, but will receive the extensive supervised program after the experimental period. Discussion: It is expected that particularly the supervised combination of balance and strength / power training will improve performance in variables of balance, strength / power, body composition, cognitive function, psychosocial well-being, and falls self-efficacy of older adults. In addition, information regarding fall risk assessment, dose-response-relations, detraining effects, and supervision of training will be provided. Further, training-induced health-relevant changes, such as improved performance in activities of daily living, cognitive function, and quality of life, as well as a reduced risk for falls may help to lower costs in the health care system. Finally, practitioners, therapists, and instructors will be provided with a scientifically evaluated feasible, safe, and easy-to-administer exercise program for fall prevention. KW - seniors KW - fall risk assessment KW - resistance training KW - postural stability Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-427104 SN - 1866-8364 IS - 604 ER - TY - JOUR A1 - Gschwind, Yves J. A1 - Kressig, Reto W. A1 - Lacroix, Andre A1 - Mühlbauer, Thomas A1 - Pfenninger, Barbara A1 - Granacher, Urs T1 - A best practice fall prevention exercise program to improve balance, strength/power, and psychosocial health in older adults - study protocol for a randomized controlled trial JF - BMC geriatrics N2 - Background: With increasing age neuromuscular deficits (e.g., sarcopenia) may result in impaired physical performance and an increased risk for falls. Prominent intrinsic fall-risk factors are age-related decreases in balance and strength / power performance as well as cognitive decline. Additional studies are needed to develop specifically tailored exercise programs for older adults that can easily be implemented into clinical practice. Thus, the objective of the present trial is to assess the effects of a fall prevention program that was developed by an interdisciplinary expert panel on measures of balance, strength / power, body composition, cognition, psychosocial well-being, and falls self-efficacy in healthy older adults. Additionally, the time-related effects of detraining are tested. Methods/Design: Healthy old people (n = 54) between the age of 65 to 80 years will participate in this trial. The testing protocol comprises tests for the assessment of static / dynamic steady-state balance (i.e., Sharpened Romberg Test, instrumented gait analysis), proactive balance (i.e., Functional Reach Test; Timed Up and Go Test), reactive balance (i.e., perturbation test during bipedal stance; Push and Release Test), strength (i.e., hand grip strength test; Chair Stand Test), and power (i.e., Stair Climb Power Test; countermovement jump). Further, body composition will be analysed using a bioelectrical impedance analysis system. In addition, questionnaires for the assessment of psychosocial (i.e., World Health Organisation Quality of Life Assessment-Bref), cognitive (i.e., Mini Mental State Examination), and fall risk determinants (i.e., Fall Efficacy Scale -International) will be included in the study protocol. Participants will be randomized into two intervention groups or the control / waiting group. After baseline measures, participants in the intervention groups will conduct a 12-week balance and strength / power exercise intervention 3 times per week, with each training session lasting 30 min. (actual training time). One intervention group will complete an extensive supervised training program, while the other intervention group will complete a short version (` 3 times 3') that is home-based and controlled by weekly phone calls. Post-tests will be conducted right after the intervention period. Additionally, detraining effects will be measured 12 weeks after program cessation. The control group / waiting group will not participate in any specific intervention during the experimental period, but will receive the extensive supervised program after the experimental period. Discussion: It is expected that particularly the supervised combination of balance and strength / power training will improve performance in variables of balance, strength / power, body composition, cognitive function, psychosocial well-being, and falls self-efficacy of older adults. In addition, information regarding fall risk assessment, dose-response-relations, detraining effects, and supervision of training will be provided. Further, training-induced health-relevant changes, such as improved performance in activities of daily living, cognitive function, and quality of life, as well as a reduced risk for falls may help to lower costs in the health care system. Finally, practitioners, therapists, and instructors will be provided with a scientifically evaluated feasible, safe, and easy-to-administer exercise program for fall prevention. KW - Seniors KW - Fall risk assessment KW - Resistance training KW - Postural stability Y1 - 2013 U6 - https://doi.org/10.1186/1471-2318-13-105 SN - 1471-2318 VL - 13 IS - 4 PB - BioMed Central CY - London ER - TY - JOUR A1 - Badalyan, Artavazd A1 - Neumann-Schaal, Meina A1 - Leimkühler, Silke A1 - Wollenberger, Ursula T1 - A Biosensor for aromatic aldehydes comprising the mediator dependent PaoABC-Aldehyde oxidoreductase JF - Electroanalysis : an international journal devoted to fundamental and practical aspects of electroanalysis N2 - A novel aldehyde oxidoreductase (PaoABC) from Escherichia coli was utilized for the development of an oxygen insensitive biosensor for benzaldehyde. The enzyme was immobilized in polyvinyl alcohol and currents were measured for aldehyde oxidation with different one and two electron mediators with the highest sensitivity for benzaldehyde in the presence of hexacyanoferrate(III). The benzaldehyde biosensor was optimized with respect to mediator concentration, enzyme loading and pH using potassium hexacyanoferrate(III). The linear measuring range is between 0.5200 mu M benzaldehyde. In correspondence with the substrate selectivity of the enzyme in solution the biosensor revealed a preference for aromatic aldehydes and less effective conversion of aliphatic aldehydes. The biosensor is oxygen independent, which is a particularly attractive feature for application. The biosensor can be applied to detect contaminations with benzaldehyde in solvents such as benzyl alcohol, where traces of benzaldehyde in benzyl alcohol down to 0.0042?% can be detected. KW - Aldehyde oxidoreductase KW - Benzaldehyde KW - Biosensor KW - Aromatic aldehydes KW - Molybdenum cofactor Y1 - 2013 U6 - https://doi.org/10.1002/elan.201200362 SN - 1040-0397 VL - 25 IS - 1 SP - 101 EP - 108 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Ulm, Lena A1 - Wohlrapp, Dorota A1 - Meinzer, Marcus A1 - Steinicke, Robert A1 - Schatz, Alexej A1 - Denzler, Petra A1 - Klehmet, Juliane A1 - Dohle, Christian A1 - Niedeggen, Michael A1 - Meisel, Andreas A1 - Winter, York T1 - A circle-monitor for computerised assessment of visual neglect in peripersonal space JF - PLoS one N2 - Current assessment of visual neglect involves paper-and-pencil tests or computer-based tasks. Both have been criticised because of their lack of ecological validity as target stimuli can only be presented in a restricted visual range. This study examined the user-friendliness and diagnostic strength of a new "Circle-Monitor" (CM), which enlarges the range of the peripersonal space, in comparison to a standard paper-and-pencil test (Neglect-Test, NET). Methods: Ten stroke patients with neglect and ten age-matched healthy controls were examined by the NET and the CM test comprising of four subtests (Star Cancellation, Line Bisection, Dice Task, and Puzzle Test). Results: The acceptance of the CM in elderly controls and neglect patients was high. Participants rated the examination by CM as clear, safe and more enjoyable than NET. Healthy controls performed at ceiling on all subtests, without any systematic differences between the visual fields. Both NET and CM revealed significant differences between controls and patients in Line Bisection, Star Cancellation and visuo-constructive tasks (NET: Figure Copying, CM: Puzzle Test). Discriminant analyses revealed cross-validated assignment of patients and controls to groups was more precise when based on the CM (hit rate 90%) as compared to the NET (hit rate 70%). Conclusion: The CM proved to be a sensitive novel tool to diagnose visual neglect symptoms quickly and accurately with superior diagnostic validity compared to a standard neglect test while being well accepted by patients. Due to its upgradable functions the system may also be a valuable tool not only to test for non-visual neglect symptoms, but also to provide treatment and assess its outcome. Y1 - 2013 U6 - https://doi.org/10.1371/journal.pone.0082892 SN - 1932-6203 VL - 8 IS - 12 PB - PLoS CY - San Fransisco ER - TY - INPR A1 - Fedchenko, Dmitry A1 - Tarkhanov, Nikolai Nikolaevich T1 - A Class of Toeplitz Operators in Several Variables N2 - We introduce the concept of Toeplitz operator associated with the Laplace-Beltrami operator on a compact Riemannian manifold with boundary. We characterise those Toeplitz operators which are Fredholm, thus initiating the index theory. T3 - Preprints des Instituts für Mathematik der Universität Potsdam - 2(2013)17 KW - Cauchy data spaces KW - Laplace-Beltrami operator KW - Toeplitz operators KW - Fredholm property Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-68932 SN - 2193-6943 ER - TY - JOUR A1 - Wang, Jing A1 - Fritzsch, Claire A1 - Bernarding, Johannes A1 - Holtze, Susanne A1 - Mauritz, Karl-Heinz A1 - Brunetti, Maddalena A1 - Dohle, Christian T1 - A comparison of neural mechanisms in mirror therapy and movement observation therapy JF - Journal of rehabilitation medicine : official journal of the UEMS European Board of Physical and Rehabilitation Medicine N2 - Objective: To compare lateralized cerebral activations elicited during self-initiated movement mirroring and observation of movements. Subjects: A total of 15 right-handed healthy subjects, age range 22-56 years. Methods: Functional imaging study comparing movement mirroring with movement observation, in both hands, in an otherwise identical setting. Imaging data were analysed using statistical parametric mapping software, with significance threshold set at p<0.01 (false discovery rate) and a minimum cluster size of 20 voxels. Results: Movement mirroring induced additional activation in primary and higher-order visual areas strictly contralateral to the limb seen by the subject. There was no significant difference of brain activity when comparing movement observation of somebody else's right hand with left hand. Conclusion: Lateralized cerebral activations are elicited by inversion of visual feedback (movement mirroring), but not by movement observation. KW - fMRI KW - mirror KW - movement KW - observation KW - precuneus Y1 - 2013 U6 - https://doi.org/10.2340/16501977-1127 SN - 1650-1977 VL - 45 IS - 4 SP - 410 EP - 413 PB - Foundation for Rehabilitation Information CY - Uppsala ER - TY - JOUR A1 - Allan, Eric A1 - Weisser, Wolfgang W. A1 - Fischer, Markus A1 - Schulze, Ernst-Detlef A1 - Weigelt, Alexandra A1 - Roscher, Christiane A1 - Baade, Jussi A1 - Barnard, Romain L. A1 - Bessler, Holger A1 - Buchmann, Nina A1 - Ebeling, Anne A1 - Eisenhauer, Nico A1 - Engels, Christof A1 - Fergus, Alexander J. F. A1 - Gleixner, Gerd A1 - Gubsch, Marlen A1 - Halle, Stefan A1 - Klein, Alexandra-Maria A1 - Kertscher, Ilona A1 - Kuu, Annely A1 - Lange, Markus A1 - Le Roux, Xavier A1 - Meyer, Sebastian T. A1 - Migunova, Varvara D. A1 - Milcu, Alexandru A1 - Niklaus, Pascal A. A1 - Oelmann, Yvonne A1 - Pasalic, Esther A1 - Petermann, Jana S. A1 - Poly, Franck A1 - Rottstock, Tanja A1 - Sabais, Alexander C. W. A1 - Scherber, Christoph A1 - Scherer-Lorenzen, Michael A1 - Scheu, Stefan A1 - Steinbeiss, Sibylle A1 - Schwichtenberg, Guido A1 - Temperton, Vicky A1 - Tscharntke, Teja A1 - Voigt, Winfried A1 - Wilcke, Wolfgang A1 - Wirth, Christian A1 - Schmid, Bernhard T1 - A comparison of the strength of biodiversity effects across multiple functions JF - Oecologia N2 - In order to predict which ecosystem functions are most at risk from biodiversity loss, meta-analyses have generalised results from biodiversity experiments over different sites and ecosystem types. In contrast, comparing the strength of biodiversity effects across a large number of ecosystem processes measured in a single experiment permits more direct comparisons. Here, we present an analysis of 418 separate measures of 38 ecosystem processes. Overall, 45 % of processes were significantly affected by plant species richness, suggesting that, while diversity affects a large number of processes not all respond to biodiversity. We therefore compared the strength of plant diversity effects between different categories of ecosystem processes, grouping processes according to the year of measurement, their biogeochemical cycle, trophic level and compartment (above- or belowground) and according to whether they were measures of biodiversity or other ecosystem processes, biotic or abiotic and static or dynamic. Overall, and for several individual processes, we found that biodiversity effects became stronger over time. Measures of the carbon cycle were also affected more strongly by plant species richness than were the measures associated with the nitrogen cycle. Further, we found greater plant species richness effects on measures of biodiversity than on other processes. The differential effects of plant diversity on the various types of ecosystem processes indicate that future research and political effort should shift from a general debate about whether biodiversity loss impairs ecosystem functions to focussing on the specific functions of interest and ways to preserve them individually or in combination. KW - Bottom-up effects KW - Carbon cycling KW - Ecological synthesis KW - Ecosystem processes KW - Grasslands KW - Jena experiment KW - Nitrogen cycling Y1 - 2013 U6 - https://doi.org/10.1007/s00442-012-2589-0 SN - 0029-8549 VL - 173 IS - 1 SP - 223 EP - 237 PB - Springer CY - New York ER - TY - JOUR A1 - Mietzner, Dana A1 - Kamprath, Martin T1 - A competence portfolio for professionals in the creative industries JF - Creativity and innovation management N2 - Within the last decade, the role of the Creative Industries has grown to become an important part of the economic system. The increasing acceleration of new developments in media and ICT technologies greatly affected the Creative Industries' dynamic with a direct impact on the people working in this sector. Since only a few studies focus on competences needs, more or less isolated from the trends within the industry, we address the topic of individual competence shifts in the turbulent environment of the Creative Industries. We investigated the trends regarding competence shifts and their implications as well as the competences which are essential for creative professionals. We conducted a broad literature review as well as a qualitative study, which includes interviews and workshops with industry experts on trends within the Creative Industries and corresponding dimensions and demands for competences. We present four requirements that call for shifts in the education of competences. Based on the discussion of requirements, we present a competence portfolio for the Creative Industries along the dimensions of professional, methodological and personal-social competences. The portfolio clearly indicates which competences should be taken into consideration for the development of curricula and study programmes in the education of creative professionals. A generalization of these findings suggests new challenges for companies relying on creative professionals. Y1 - 2013 U6 - https://doi.org/10.1111/caim.12026 SN - 0963-1690 VL - 22 IS - 3 SP - 280 EP - 294 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Kramer, Markus A1 - Kleinpeter, Erich T1 - A conformational study of N-acetyl glucosamine derivatives utilizing residual dipolar couplings Y1 - 2013 SN - 1090-7807 ER - TY - JOUR A1 - Schmidt, Bernd A1 - Berger, René T1 - A deacetylation-diazotation-coupling sequence - palladium-catalyzed CC bond formation with acetanilides as formal leaving groups JF - Advanced synthesis & catalysis N2 - Acetanilides can be deacetylated and diazotized in situ, and subsequently used in Pd-catalyzed coupling reactions without isolation of the diazonium intermediate. Heck reactions, Suzuki cross-coupling reactions, and a Pd-catalyzed [2+2+1]cycloaddition have been investigated as terminating CC bond-forming steps of this one-flask sequence. The sequence does not require the exchange of solvents or removal of by-products between the individual steps, but proceeds by addition of reagents and catalysts in due course. KW - diazo compounds KW - Heck reaction KW - homogeneous catalysis KW - palladium KW - Suzuki coupling Y1 - 2013 U6 - https://doi.org/10.1002/adsc.201200929 SN - 1615-4150 VL - 355 IS - 2-3 SP - 463 EP - 476 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Naze, Yael A1 - Oskinova, Lida A1 - Gosset, Eric T1 - A detailed x-ray investigation of zeta puppis - II. the variability on short and long timescales JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - Stellar winds are a crucial component of massive stars, but their exact properties still remain uncertain. To shed some light on this subject, we have analyzed an exceptional set of X-ray observations of zeta Puppis, one of the closest and brightest massive stars. The sensitive light curves that were derived reveal two major results. On the one hand, a slow modulation of the X-ray flux (with a relative amplitude of up to 15% over 16 hr in the 0.3-4.0 keV band) is detected. Its characteristic timescale cannot be determined with precision, but amounts from one to several days. It could be related to corotating interaction regions, known to exist in zeta Puppis from UV observations. Hour-long changes, linked to flares or to the pulsation activity, are not observed in the last decade covered by the XMM observations; the 17 hr tentative period, previously reported in a ROSAT analysis, is not confirmed either and is thus transient, at best. On the other hand, short-term changes are surprisingly small (<1% relative amplitude for the total energy band). In fact, they are compatible solely with the presence of Poisson noise in the data. This surprisingly low level of short-term variability, in view of the embedded wind-shock origin, requires a very high fragmentation of the stellar wind, for both absorbing and emitting features (>10(5) parcels, comparing with a two-dimensional wind model). This is the first time that constraints have been placed on the number of clumps in an O-type star wind and from X-ray observations. KW - stars: early-type KW - stars: individual (zeta Pup) KW - X-rays: stars Y1 - 2013 U6 - https://doi.org/10.1088/0004-637X/763/2/143 SN - 0004-637X VL - 763 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Bukovinszky, Tibor A1 - Helmsing, Nico R. A1 - Grau, R. A. A1 - Bakker, Elisabeth S. A1 - Bezemer, T. Martijn A1 - Vos, Matthijs A1 - Uittenhout, H. A1 - Verschoor, A. M. T1 - A device to study the behavioral responses of zooplankton to food quality and quantity JF - Journal of insect behavior N2 - In order to explore the behavioral mechanisms underlying aggregation of foragers on local resource patches, it is necessary to manipulate the location, quality and quantity of food patches. This requires careful control over the conditions in the foraging arena, which may be a challenging task in the case of aquatic resource-consumer systems, like that of freshwater zooplankton feeding on suspended algal cells. We present an experimental tool designed to aid behavioral ecologists in exploring the consequences of resource characteristics for zooplankton aggregation behavior and movement decisions under conditions where the boundaries and characteristics (quantity and quality) of food patches can be standardized. The aggregation behavior of Daphnia magna and D. galeata x hyalina was tested in relation to i) the presence or absence of food or ii) food quality, where algae of high or low nutrient (phosphorus) content were offered in distinct patches. Individuals of both Daphnia species chose tubes containing food patches and D. galeata x hyalina also showed a preference towards food patches of high nutrient content. We discuss how the described equipment complements other behavioral approaches providing a useful tool to understand animal foraging decisions in environments with heterogeneous resource distributions. KW - Foraging behavior KW - behavioral choice KW - food preference KW - Daphnia KW - flow-through vessel Y1 - 2013 U6 - https://doi.org/10.1007/s10905-012-9366-0 SN - 0892-7553 VL - 26 IS - 4 SP - 453 EP - 465 PB - Springer CY - New York ER - TY - THES A1 - Albrecht, Torsten T1 - A dynamic memory of fracture processes in ice shelves Y1 - 2013 CY - Potsdam ER - TY - JOUR A1 - Krause, Florian A1 - Bekkering, Harold A1 - Lindemann, Oliver T1 - A feeling for numbers shared metric for symbolic and tactile numerosities JF - Frontiers in psychology N2 - Evidence for an approximate analog system of numbers has been provided by the finding that the comparison of two numerals takes longer and is more error-prone if the semantic distance between the numbers becomes smaller (so-called numerical distance effect). Recent embodied theories suggest that analog number representations are based on previous sensory experiences and constitute therefore a common magnitude metric shared by multiple domains. Here we demonstrate the existence of a cross-modal semantic distance effect between symbolic and tactile numerosities. Participants received tactile stimulations of different amounts of fingers while reading Arabic digits and indicated verbally whether the amount of stimulated fingers was different from the simultaneously presented digit or not. The larger the semantic distance was between the two numerosities, the faster and more accurate participants made their judgments. This cross-modal numerosity distance effect suggests a direct connection between tactile sensations and the concept of numerical magnitude. A second experiment replicated the interaction between symbolic and tactile numerosities and showed that this effect is not modulated by the participants' finger counting habits. Taken together, our data provide novel evidence for a shared metric for symbolic and tactile numerosities as an instance of an embodied representation of numbers. KW - number cognition KW - tactile perception KW - finger counting Y1 - 2013 U6 - https://doi.org/10.3389/fpsyg.2013.00007 SN - 1664-1078 VL - 4 IS - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Engelmann, Felix A1 - Vasishth, Shravan A1 - Engbert, Ralf A1 - Kliegl, Reinhold T1 - A framework for modeling the interaction of syntactic processing and eye movement control JF - Topics in cognitive science N2 - We explore the interaction between oculomotor control and language comprehension on the sentence level using two well-tested computational accounts of parsing difficulty. Previous work (Boston, Hale, Vasishth, & Kliegl, 2011) has shown that surprisal (Hale, 2001; Levy, 2008) and cue-based memory retrieval (Lewis & Vasishth, 2005) are significant and complementary predictors of reading time in an eyetracking corpus. It remains an open question how the sentence processor interacts with oculomotor control. Using a simple linking hypothesis proposed in Reichle, Warren, and McConnell (2009), we integrated both measures with the eye movement model EMMA (Salvucci, 2001) inside the cognitive architecture ACT-R (Anderson et al., 2004). We built a reading model that could initiate short Time Out regressions (Mitchell, Shen, Green, & Hodgson, 2008) that compensate for slow postlexical processing. This simple interaction enabled the model to predict the re-reading of words based on parsing difficulty. The model was evaluated in different configurations on the prediction of frequency effects on the Potsdam Sentence Corpus. The extension of EMMA with postlexical processing improved its predictions and reproduced re-reading rates and durations with a reasonable fit to the data. This demonstration, based on simple and independently motivated assumptions, serves as a foundational step toward a precise investigation of the interaction between high-level language processing and eye movement control. KW - Sentence comprehension KW - Eye movements KW - Reading KW - Parsing difficulty KW - Working memory KW - Surprisal KW - Computational modeling Y1 - 2013 U6 - https://doi.org/10.1111/tops.12026 SN - 1756-8757 VL - 5 IS - 3 SP - 452 EP - 474 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Li, Jian A1 - Chen, You-Peng A1 - Wang, Zi-Neng A1 - Liu, Tie-Bin A1 - Chen, Dan A1 - Dong, Yun-Peng A1 - Hocher, Berthold T1 - A functional fetal HSD11B2[CA]n microsatellite polymorphism is associated with maternal serum cortisol concentrations in pregnant women JF - Kidney & blood pressure research : official organ of the Gesellschaft für Nephrologie N2 - Background/Aims: Cortisol plays an important role during pregnancy. It controls maternal glucose metabolism and fetal development. Cortisol metabolism is partially controlled by the 11b-HSD2. This enzyme is expressed in the kidney and human placenta. The activity of the enzyme is partially controlled by functional polymorphisms: the HSD11B2[CA]n microsatellite polymorphism. The impact of this functional gene polymorphism on cortisol metabolism and potential effects on the newborn's is unknown so far. Methods: In the current prospective birth cohort study in southern Asia, we analyzed the association of the HSD11B2[CA]n microsatellite polymorphisms in 187 mothers and their newborn's on maternal and newborn's serum cortisol concentrations. Results: Using multivariable regression analyses considering known confounding ( gestational age, newborn's gender, the labor uterine contraction states and the timing during the day of blood taking), we showed that the fetal HSD11B2[CA]n microsatellite polymorphisms in the first intron was related to maternal cortisol concentration ( R2=0.26, B=96.27, p=0.007), whereas as the newborn's cortisol concentrations were independent of fetal and maternal HSD11B2[CA] n microsatellite polymorphism. Conclusions: Our study showed for the first time that the fetal HSD11B2[CA]n microsatellite polymorphism of the HSD11B2 gene in healthy uncomplicated human pregnancy is associated with maternal cortisol concentration. This indicates that fetal genes controlling cortisol metabolism may affect maternal cortisol concentration and hence physiology in healthy pregnant women. KW - Pregnancy KW - Placenta KW - Cortisol vertical bar metabolism KW - 11 beta-hydroxysteroid dehydrogenase 2 KW - HSD11B2[CA]n polymorphism Y1 - 2013 U6 - https://doi.org/10.1159/000355761 SN - 1420-4096 SN - 1423-0143 VL - 38 IS - 1 SP - 132 EP - 141 PB - Karger CY - Basel ER - TY - JOUR A1 - Shojaei-Fard, Ali T1 - A GEOMETRIC PERSPECTIVE ON COUNTERTERMS RELATED TO DYSON-SCHWINGER EQUATIONS JF - INTERNATIONAL JOURNAL OF MODERN PHYSICS A N2 - We study Dyson-Schwinger equations (DSEs) in terms of some groups of diffeographisms to provide a new geometric formulation for their corresponding counterterms on the basis of systems of ordinary differential equations. KW - Dyson-Schwinger equations KW - Hopf algebra of Feynman diagrams KW - counterterms KW - Picard-Fuchs equations KW - equi-singular connections Y1 - 2013 U6 - https://doi.org/10.1142/S0217751X13501704 SN - 0217-751X SN - 1793-656X VL - 28 IS - 32 PB - WORLD SCIENTIFIC PUBL CO PTE LTD CY - SINGAPORE ER - TY - JOUR A1 - Fahle, Marcus A1 - Dietrich, Ottfried A1 - Lischeid, Gunnar T1 - A guideline for developing an initial hydrological monotoring network as a basis for water management in artificially drained wetlands JF - Irrigation and drainage N2 - Reliable hydrological monitoring is the basis for sound water management in drained wetlands. Since statistical methods cannot be employed for unobserved or sparsely monitored areas, the primary design (first set-up) may be arbitrary in most instances. The objective of this paper is therefore to provide a guideline for designing the initial hydrological monitoring network. A scheme is developed that handles different parts of monitoring and hydrometry in wetlands, focusing on the positioning of surface water and groundwater gauges. For placement of the former, control units are used which correspond to areas whose water levels can be regulated separately. The latter are arranged depending on hydrological response units, defined by combinations of soil type and land use, and the chosen surface water monitoring sites. A practical application of the approach is shown for an investigation area in the Spreewald region in north-east Germany. The presented scheme leaves a certain degree of freedom to its user, allowing the inclusion of expert knowledge or special concerns. Based on easily obtainable data, the developed hydrological network serves as a first step in the iterative procedure of monitoring network optimisation. Copyright (c) 2013 John Wiley & Sons, Ltd. KW - monitoring network KW - wetland KW - sampling locations KW - controlled drainage KW - ditch system KW - measurement frequency Y1 - 2013 U6 - https://doi.org/10.1002/ird.1744 SN - 1531-0353 SN - 1531-0361 VL - 62 IS - 4 SP - 524 EP - 536 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Ast, Sandra A1 - Schwarze, Thomas A1 - Müller, Holger A1 - Sukhanov, Aleksey A1 - Michaelis, Stefanie A1 - Wegener, Joachim A1 - Wolfbeis, Otto S. A1 - Körzdörfer, Thomas A1 - Dürkop, Axel A1 - Holdt, Hans-Jürgen T1 - A highly K+-Selective Phenylaza-[18]crown-6-Lariat-Ether-Based Fluoroionophore and its application in the sensing of K+ Ions with an optical sensor film and in cells JF - Chemistry - a European journal N2 - Herein, we report the synthesis of two phenylaza-[18]crown-6 lariat ethers with a coumarin fluorophore (1 and 2) and we reveal that compound 1 is an excellent probe for K+ ions under simulated physiological conditions. The presence of a 2-methoxyethoxy lariat group at the ortho position of the anilino moiety is crucial to the substantially increased stability of compounds 1 and 2 over their lariat-free phenylaza-[18] crown-6 ether analogues. Probe 1 shows a high K+/Na+ selectivity and a 2.5-fold fluorescence enhancement was observed in the presence of 100 mm K+ ions. A fluorescent membrane sensor, which was prepared by incorporating probe 1 into a hydrogel, showed a fully reversible response, a response time of 150 s, and a signal change of 7.8% per 1 mm K+ within the range 1-10 mm K+. The membrane was easily fabricated (only a single sensing layer on a solid polyester support), yet no leaching was observed. Moreover, compound 1 rapidly permeated into cells, was cytocompatible, and was suitable for the fluorescent imaging of K+ ions on both the extracellular and intracellular levels. KW - crown compounds KW - fluorescence KW - gels KW - potassium KW - sensors Y1 - 2013 U6 - https://doi.org/10.1002/chem.201302350 SN - 0947-6539 SN - 1521-3765 VL - 19 IS - 44 SP - 14911 EP - 14917 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Tikhonenko, Irina A1 - Magidson, Valentin A1 - Gräf, Ralph A1 - Khodjakov, Alexey A1 - Koonce, Michael P. T1 - A kinesin-mediated mechanism that couples centrosomes to nuclei JF - Cellular and molecular life sciences N2 - The M-type kinesin isoform, Kif9, has recently been implicated in maintaining a physical connection between the centrosome and nucleus in Dictyostelium discoideum. However, the mechanism by which Kif9 functions to link these two organelles remains obscure. Here we demonstrate that the Kif9 protein is localized to the nuclear envelope and is concentrated in the region underlying the centrosome point of attachment. Nuclear anchorage appears mediated through a specialized transmembrane domain located in the carboxyl terminus. Kif9 interacts with microtubules in in vitro binding assays and effects an endwise depolymerization of the polymer. These results suggest a model whereby Kif9 is anchored to the nucleus and generates a pulling force that reels the centrosome up against the nucleus. This is a novel activity for a kinesin motor, one important for progression of cells into mitosis and to ensure centrosome-nuclear parity in a multinuclear environment. KW - Centrosome KW - Kinesin KW - Microtubule KW - Dictyostelium Y1 - 2013 U6 - https://doi.org/10.1007/s00018-012-1205-0 SN - 1420-682X VL - 70 IS - 7 SP - 1285 EP - 1296 PB - Springer CY - Basel ER - TY - JOUR A1 - Cao, Xianyong A1 - Ni, Jian A1 - Herzschuh, Ulrike A1 - Wang, Yongbo A1 - Zhao, Yan T1 - A late quaternary pollen dataset from eastern continental Asia for vegetation and climate reconstructions set up and evaluation JF - Review of palaeobotany and palynology : an international journal N2 - A total of 271 pollen records were selected from a large collection of both raw and digitized pollen spectra from eastern continental Asia (70 degrees-135 degrees E and 18 degrees-55 degrees N). Following pollen percentage recalculations, taxonomic homogenization, and age-depth model revision, the pollen spectra were interpolated at a 500-year resolution and a taxonomically harmonized and temporally standardized fossil pollen dataset established with 226 pollen taxa, covering the last 22 cal lea. Of the 271 pollen records, 85% were published since 1990, with reliable chronologies and high temporal resolutions; of these, 50% have raw data with complete pollen assemblages, ensuring the quality of this dataset The pollen records available for each 500-year time slice are well distributed over all main vegetation types and climatic zones of the study area, making their pollen spectra suitable for paleovegetation and paleoclimate research. Such a dataset can be used as an example for the development of similar datasets for other regions of the world. KW - fossil pollen KW - eastern asia KW - pollen taxa KW - age-depth model KW - resampling Y1 - 2013 U6 - https://doi.org/10.1016/j.revpalbo.2013.02.003 SN - 0034-6667 VL - 194 IS - 13 SP - 21 EP - 37 PB - Elsevier CY - Amsterdam ER - TY - INPR A1 - Wallenta, Daniel T1 - A Lefschetz fixed point formula for elliptic quasicomplexes N2 - In a recent paper with N. Tarkhanov, the Lefschetz number for endomorphisms (modulo trace class operators) of sequences of trace class curvature was introduced. We show that this is a well defined, canonical extension of the classical Lefschetz number and establish the homotopy invariance of this number. Moreover, we apply the results to show that the Lefschetz fixed point formula holds for geometric quasiendomorphisms of elliptic quasicomplexes. T3 - Preprints des Instituts für Mathematik der Universität Potsdam - 2(2013)12 KW - Perturbed complexes KW - curvature KW - Lefschetz number KW - fixed point formula Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-67016 ER - TY - JOUR A1 - Krentz, Eva Maria A1 - Warschburger, Petra T1 - A longitudinal investigation of sports-related risk factors for disordered eating in aesthetic sports JF - Scandinavian journal of medicine & science in sports N2 - Previous studies have indicated a higher risk of disordered eating in certain types of elite sports such as aesthetic sports (e.g., rhythmical gymnastics, figure skating). But even though some studies on risk factors for disordered eating in sports exist, most research on this topic is based on cross-sectional data with limitations on causal inferences. We examined sports-related risk factors for disordered eating in a 1-year longitudinal study with two assessment points. The participants were 65 adolescent athletes from aesthetic sports (mean age 14.0 +/- 2.2years) who completed measures of disordered eating, social pressure from the sports environment, sports-related body dissatisfaction, desire to be leaner to improve sports performance, and emotional distress resulting from missed exercise sessions. All variables were relatively stable in the mean. Individual changes in the desire to be leaner to improve sports performance were associated with individual changes in disordered eating. Furthermore, a cross-lagged partial correlation analysis showed that the desire to be leaner to improve sports performance was predictive of disordered eating and not vice versa. The results of our study indicate that athletes are more at risk for disordered eating if they believe it is possible to enhance their sports performance through weight regulation. KW - adolescent KW - eating disorder KW - elite athlete KW - prospective KW - two-wave panel Y1 - 2013 U6 - https://doi.org/10.1111/j.1600-0838.2011.01380.x SN - 0905-7188 VL - 23 IS - 3 SP - 303 EP - 310 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Walter, Marius J. A1 - Trauth, Martin H. T1 - A MATLAB based orientation analysis of Acheulean handaxe accumulations in Olorgesailie and Kariandusi, Kenya Rift JF - Journal of human evolution N2 - The Pleistocene archeological record in East Africa has revealed unusual accumulations of Acheulean handaxes at prehistoric sites. In particular, there has been intensive debate concerning whether the artifact accumulation at the Middle Pleistocene Olorgesailie (Southern Kenya Rift) and Kariandusi (Central Kenya Rift) sites were a result of fluvial reworking or of in situ deposition by hominids. We used a two-step approach to test the hypothesis of fluvial reworking. Firstly, the behavior of handaxes in water currents was investigated in a current flume and the flow threshold required to reorientate the handaxes was determined. The results of these experiments suggested that, in relatively high energy and non-steady flow conditions, handaxes will reorientate themselves perpendicular to the current direction. Secondly, an automated image analysis routine was developed and applied to archeological plans from three Acheulean sites, two at Olorgesailie and one at Kariandusi, in order to determine the orientations of the handaxes. A Rayleigh test was then applied to the orientation data to test for a preferred orientation. The results revealed that the handaxes at the Upper Kariandusi Site and the Olorgesailie Main Site Mid Trench had a preferential orientation, suggesting reworking by a paleocurrent. The handaxes from the Olorgesailie Main Site H/6A, however, appeared to be randomly oriented and in situ deposition by the producers therefore remains a possibility. KW - Excavation plan KW - Artifact KW - Flume channel KW - Shape detection KW - Rayleigh test Y1 - 2013 U6 - https://doi.org/10.1016/j.jhevol.2013.02.011 SN - 0047-2484 VL - 64 IS - 6 SP - 569 EP - 581 PB - Elsevier CY - London ER - TY - JOUR A1 - Delgrande, James A1 - Schaub, Torsten H. A1 - Tompits, Hans A1 - Woltran, Stefan T1 - A model-theoretic approach to belief change in answer set programming JF - ACM transactions on computational logic N2 - We address the problem of belief change in (nonmonotonic) logic programming under answer set semantics. Our formal techniques are analogous to those of distance-based belief revision in propositional logic. In particular, we build upon the model theory of logic programs furnished by SE interpretations, where an SE interpretation is a model of a logic program in the same way that a classical interpretation is a model of a propositional formula. Hence we extend techniques from the area of belief revision based on distance between models to belief change in logic programs. We first consider belief revision: for logic programs P and Q, the goal is to determine a program R that corresponds to the revision of P by Q, denoted P * Q. We investigate several operators, including (logic program) expansion and two revision operators based on the distance between the SE models of logic programs. It proves to be the case that expansion is an interesting operator in its own right, unlike in classical belief revision where it is relatively uninteresting. Expansion and revision are shown to satisfy a suite of interesting properties; in particular, our revision operators satisfy all or nearly all of the AGM postulates for revision. We next consider approaches for merging a set of logic programs, P-1,...,P-n. Again, our formal techniques are based on notions of relative distance between the SE models of the logic programs. Two approaches are examined. The first informally selects for each program P-i those models of P-i that vary the least from models of the other programs. The second approach informally selects those models of a program P-0 that are closest to the models of programs P-1,...,P-n. In this case, P-0 can be thought of as a set of database integrity constraints. We examine these operators with regards to how they satisfy relevant postulate sets. Last, we present encodings for computing the revision as well as the merging of logic programs within the same logic programming framework. This gives rise to a direct implementation of our approach in terms of off-the-shelf answer set solvers. These encodings also reflect the fact that our change operators do not increase the complexity of the base formalism. KW - Theory KW - Answer set programming KW - belief revision KW - belief merging KW - program encodings KW - strong equivalence Y1 - 2013 U6 - https://doi.org/10.1145/2480759.2480766 SN - 1529-3785 VL - 14 IS - 2 PB - Association for Computing Machinery CY - New York ER -