TY - GEN A1 - Esguerra, Alejandro ED - Esguerra, Alejandro ED - Helmerich, Nicole ED - Risse, Thomas T1 - Conclusion T2 - Sustainability Politics and Limited Statehood: Contesting the New Modes of Governance N2 - This chapter revisits the role of the new modes of governance in areas of limited statehood. First, it states that there is no linear relationship between degrees of statehood and the overall effectiveness of new modes of sustainability governance. Second, the chapter states that, in most of the cases, national governments are hesitant or even actively hamper the development of new modes of governance. Third, it shows that the absence of the shadow of hierarchy can indeed lead to ineffective new modes of governance. However, the shadow of hierarchy does not necessarily need to be cast by states. Finally, the author reviews the complexities involved in participatory practices, stressing the importance of institutional structures and knowledgeable brokers. The chapter concludes by outlining fields for future research. Y1 - 2016 SN - 978-3-319-39871-6 SN - 978-3-319-39870-9 U6 - https://doi.org/10.1007/978-3-319-39871-6_9 SP - 211 EP - 224 PB - Cham CY - Basingstoke ER - TY - GEN A1 - Esguerra, Alejandro A1 - Helmerich, Nicole A1 - Risse, Thomas T1 - Introduction T2 - Sustainability Politics and Limited Statehood: Contesting the New Modes of Governance N2 - The Paris Agreement for Climate Change or the Sustainable Development Goals (SDGs) rely on new modes of governance for implementation. Indeed, new modes of governance such as market-based instruments, public-private partnerships or multi-stakeholder initiatives have been praised for playing a pivotal role in effective and legitimate sustainability governance. Yet, do they also deliver in areas of limited statehood? States such as Malaysia or the Dominican Republic partly lack the ability to implement and enforce rules; their statehood is limited. This introduction provides the analytical framework of this volume and critically examines the performance of new modes of governance in areas of limited statehood, drawing on the book’s in-depth case studies on issues of climate change, biodiversity, and health. Y1 - 2016 SN - 978-3-319-39871-6 SN - 978-3-319-39870-9 U6 - https://doi.org/10.1007/978-3-319-39871-6_1 SP - 1 EP - 22 PB - Palgrave Macmillan, Cham CY - Basingstoke ER - TY - GEN A1 - Esguerra, Alejandro T1 - "A Comment That Might Help Us to Move Along" BT - Brokers in Negotiation Systems T2 - Sustainability Politics and Limited Statehood : Contesting the New Modes of Governance N2 - This chapter investigates the trajectory of establishing the Forest Stewardship Council (FSC) in the early 1990s as the first private transnational certification organization with an antagonistic stakeholder body. Its main contribution is a micro-analysis of the founding assembly in 1993. By investigating the role of brokers within the negotiation as one institutional scope condition for ‘arguing’ having occurred, the chapter adopts a dramaturgical approach. It contends that the authority of brokers is not necessarily institutionally given, but needs to be gained: brokers have to prove situationally that their knowledge is relevant and that they are speaking impartially in the interest of progress rather than their own. The chapter stresses the importance of procedural knowledge which brokers provide in contrast to policy knowledge. Y1 - 2016 SN - 978-3-319-39871-6 SN - 978-3-319-39870-9 U6 - https://doi.org/10.1007/978-3-319-39871-6_2 SP - 25 EP - 46 PB - Cham CY - Basingstoke ER - TY - GEN A1 - Puschmann, Anne-Katrin A1 - Wippert, Pia-Maria T1 - A LONGITUDINAL INTERDISCIPLINARY APPROACH TO STRESS AND ITS IMPACT ON THE DEVELOPMENT OF CHRONIC PAIN T2 - Psychosomatic medicine Y1 - 2016 SN - 0033-3174 SN - 1534-7796 VL - 78 SP - A91 EP - A91 PB - Routledge, Taylor & Francis Group CY - Philadelphia ER - TY - GEN A1 - Anderson, Christopher J. A1 - Bahnik, Stepan A1 - Barnett-Cowan, Michael A1 - Bosco, Frank A. A1 - Chandler, Jesse A1 - Chartier, Christopher R. A1 - Cheung, Felix A1 - Christopherson, Cody D. A1 - Cordes, Andreas A1 - Cremata, Edward J. A1 - Della Penna, Nicolas A1 - Estel, Vivien A1 - Fedor, Anna A1 - Fitneva, Stanka A. A1 - Frank, Michael C. A1 - Grange, James A. A1 - Hartshorne, Joshua K. A1 - Hasselman, Fred A1 - Henninger, Felix A1 - van der Hulst, Marije A1 - Jonas, Kai J. A1 - Lai, Calvin K. A1 - Levitan, Carmel A. A1 - Miller, Jeremy K. A1 - Moore, Katherine S. A1 - Meixner, Johannes M. A1 - Munafo, Marcus R. A1 - Neijenhuijs, Koen I. A1 - Nilsonne, Gustav A1 - Nosek, Brian A. A1 - Plessow, Franziska A1 - Prenoveau, Jason M. A1 - Ricker, Ashley A. A1 - Schmidt, Kathleen A1 - Spies, Jeffrey R. A1 - Stieger, Stefan A1 - Strohminger, Nina A1 - Sullivan, Gavin B. A1 - van Aert, Robbie C. M. A1 - van Assen, Marcel A. L. M. A1 - Vanpaemel, Wolf A1 - Vianello, Michelangelo A1 - Voracek, Martin A1 - Zuni, Kellylynn T1 - Response to Comment on "Estimating the reproducibility of psychological science" T2 - Science N2 - Gilbert et al. conclude that evidence from the Open Science Collaboration’s Reproducibility Project: Psychology indicates high reproducibility, given the study methodology. Their very optimistic assessment is limited by statistical misconceptions and by causal inferences from selectively interpreted, correlational data. Using the Reproducibility Project: Psychology data, both optimistic and pessimistic conclusions about reproducibility are possible, and neither are yet warranted. Y1 - 2016 U6 - https://doi.org/10.1126/science.aad9163 SN - 0036-8075 SN - 1095-9203 VL - 351 SP - 1162 EP - 1165 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - GEN A1 - Keck, Wolfgang A1 - Kohler, Ulrich A1 - Nauenburg, Ricarda T1 - Quality of life in the european union and the candidate countries BT - harmonized eurobarometer datafile 1998-2002 N2 - Harmonized data file as the basis for comparative analysis of quality of life in the Candidate Countries and the European Union member states, based on seven different data sets, one Eurobarometer survey covering 13 Candidate Countries with an identical set of variables conducted in April 2002, the other six Standard Eurobarometer of different subjects and fielded in different years, each with another set of questions identical with the CC Eurobarometer. Selected aggregate indicators of quality of life ... describing the social situation in the EU15 and Candidate Countries. Y1 - 2016 U6 - https://doi.org/10.7802/1209 PB - WZB - Wissenschaftszentrum Berlin für Sozialforschung ER - TY - GEN A1 - Wischke, Christian A1 - Lendlein, Andreas T1 - Functional nanocarriers by miniaturization of polymeric materials T2 - Nanomedicine KW - function KW - microscale KW - morphology KW - nanoscale KW - polymer Y1 - 2016 U6 - https://doi.org/10.2217/nnm.16.45 SN - 1743-5889 SN - 1748-6963 VL - 11 SP - 1507 EP - 1509 PB - Future Medicine CY - London ER - TY - GEN A1 - Meere, Patrick A. A1 - Mulchrone, Kieran F. A1 - McCarthy, David J. A1 - Timmerman, Martin Jan A1 - Dewey, John F. T1 - Prelithification and synlithification tectonic foliation development in a clastic sedimentary sequence T2 - Geology Y1 - 2016 U6 - https://doi.org/10.1130/G38103Y.1 SN - 0091-7613 SN - 1943-2682 VL - 44 SP - E397 EP - E397 PB - American Institute of Physics CY - Boulder ER - TY - GEN A1 - Bubeck, Philip A1 - Aerts, Jeroen C. J. H. A1 - de Moel, Hans A1 - Kreibich, Heidi T1 - Preface: Flood-risk analysis and integrated management T2 - Natural hazards and earth system sciences Y1 - 2016 U6 - https://doi.org/10.5194/nhess-16-1005-2016 SN - 1561-8633 VL - 16 SP - 1005 EP - 1010 PB - Copernicus CY - Göttingen ER - TY - GEN A1 - Radosavljevic, Boris A1 - Lantuit, Hugues A1 - Pollard, Wayne A1 - Overduin, Pier Paul A1 - Couture, Nicole A1 - Sachs, Torsten A1 - Helm, Veit A1 - Fritz, Michael T1 - Erosion and Flooding - Threats to Coastal Infrastructure in the Arctic: A Case Study from Herschel Island, Yukon Territory, Canada (vol 39, pg 900, 2016) T2 - Estuaries and coasts : journal of the Estuarine Research Federation Y1 - 2016 U6 - https://doi.org/10.1007/s12237-016-0115-z SN - 1559-2723 SN - 1559-2731 VL - 39 SP - 1294 EP - 1295 PB - Springer CY - New York ER - TY - GEN A1 - Cajar, Anke A1 - Engbert, Ralf A1 - Laubrock, Jochen T1 - Eye movements during gaze-contingent spatial-frequency filtering of real-world scenes: Effects of filter location, cutoff, and size T2 - Perception Y1 - 2016 SN - 0301-0066 SN - 1468-4233 VL - 45 SP - 126 EP - 126 PB - Sage Publ. CY - London ER - TY - GEN A1 - Kruegel, Andre A1 - Engbert, Ralf T1 - Statistics of microsaccades indicate early frequency effects during visual word recognition T2 - Perception Y1 - 2016 SN - 0301-0066 SN - 1468-4233 VL - 45 SP - 127 EP - 127 PB - Sage Publ. CY - London ER - TY - GEN A1 - Hanack, Katja A1 - Schloer, Anja A1 - Holzloehner, Pamela A1 - Listek, Martin A1 - Bauer, Cindy A1 - Butze, Monique A1 - Micheel, Burkhard A1 - Hentschel, Christian A1 - Sowa, Mandy A1 - Roggenbuck, Dirk A1 - Schierack, Peter A1 - Fuener, Jonas A1 - Schliebs, Erik A1 - Goihl, Alexander A1 - Reinhold, Dirk T1 - Camelid nanobodies specific to human pancreatic glycoprotein 2 T2 - The journal of immunology N2 - Pancreatic secretory zymogen-granule membrane glycoprotein 2 (GP2) has been identified to be a major autoantigenic target in Crohn’s disease patients. It was discussed recently that a long and a short isoform of GP2 exists whereas the short isoform is often detected by GP2-specific autoantibodies. In the outcome of inflammatory bowel diseases, these GP2-specific autoantibodies are discussed as new serological markers for diagnosis and therapeutic monitoring. To investigate this further, camelid nanobodies were generated by phage display and selected against the short isoform of GP2 in order to isolate specific tools for the discrimination of both isoforms. Nanobodies are single domain antibodies derived from camelid heavy chain only antibodies and characterized by a high stability and solubility. The selected candidates were expressed, purified and validated regarding their binding properties in different enzyme-linked immunosorbent assays formats, immunofluorescence, immunohistochemistry and surface plasmon resonance spectroscopy. Four different nanobodies could be selected whereof three recognize the short isoform of GP2 very specifically and one nanobody showed a high binding capacity for both isoforms. The KD values measured for all nanobodies were between 1.3 nM and 2.3 pM indicating highly specific binders suitable for the application as diagnostic tool in inflammatory bowel disease. Y1 - 2016 SN - 0022-1767 SN - 1550-6606 VL - 196 SP - 313 EP - 328 PB - American Assoc. of Immunologists CY - Bethesda ER - TY - GEN A1 - Maier, Natalia A1 - Holzlöhner, Pamela A1 - Hoenow, Anja A1 - Scheunemann, Astrid A1 - Weschke, Daniel A1 - Hanack, Katja T1 - Characterization of monoclonal antibodies generated by in vitro immunization T2 - The journal of immunology N2 - Monoclonal antibodies are highly valuable tools in biomedicine but the generation by hybridoma technology is very time-consuming and elaborate. In order to circumvent the consisting drawbacks an in vitro immunization approach was established by which murine as well as human monoclonal antibodies against a viral coat protein could be developed. The in vitro immunization process was performed by isolation of murine hematopoietic stem cells or human monocytes and an in vitro differentiation into immature dendritic cells. After antigen loading the cells were co-cultivated with naive T and B lymphocytes for three days in order to obtain antigen-specific B lymphocytes in culture, followed by fusion with murine myeloma cells or human/murine heteromyeloma cells. Antigen-specific hybridomas were selected and the generated antibodies were purified and characterized in this study by ELISA, western blot, gene sequencing, affinity measurements. Further the characteristics were compared to a monoclonal antibody against the same target generated by conventional hybridoma technology. Isotype detection revealed a murine IgM and a human IgG4 antibody in comparison to an IgG1 for the conventionally generated antibody. The antibodies derived from in vitro immunization showed indeed a lower affinity for the antigen as compared to the conventionally generated one, which is probably based on the significantly shorter B cell maturation (3 days) during the immunization process. Nevertheless, they were suitable for building up a sandwich based detection system. Therefore, the in vitro immunization approach seems to be a good and particularly fast alternative to conventional hybridoma technology. Y1 - 2016 SN - 0022-1767 SN - 1550-6606 VL - 196 PB - American Assoc. of Immunologists CY - Bethesda ER - TY - GEN A1 - Holzlöhner, Pamela A1 - Butze, Monique A1 - Hebel, Nicole A1 - Weschke, Daniel A1 - Schliebs, E. A1 - Naumann, F. A1 - Füner, J. A1 - Micheel, Burkhard A1 - Hanack, Katja T1 - Monoclonal mouse antibodies against PBMC subpopulations of New World camelides T2 - European journal of immunology Y1 - 2016 SN - 0014-2980 SN - 1521-4141 VL - 46 SP - 1175 EP - 1175 PB - Wiley-Blackwell CY - Hoboken ER - TY - GEN A1 - Lechon, Tamara A1 - Sanz, Luis A1 - Pollmann, Stephan A1 - Sauer, Michael A1 - Sandalio, Luisa A1 - Lorenzo, Oscar T1 - Nitric oxide modification of plant endocytosis and PIN1 localization T2 - New biotechnology Y1 - 2016 U6 - https://doi.org/10.1016/j.nbt.2015.10.028 SN - 1871-6784 SN - 1876-4347 VL - 33 SP - 424 EP - 424 PB - Elsevier CY - Amsterdam ER - TY - GEN A1 - Hartmann, Matthias A1 - Fischer, Martin H. T1 - Exploring the numerical mind by eye-tracking: a special issue T2 - Psychological research : an international journal of perception, attention, memory, and action Y1 - 2016 U6 - https://doi.org/10.1007/s00426-016-0759-0 SN - 0340-0727 SN - 1430-2772 VL - 80 SP - 325 EP - 333 PB - Springer CY - Heidelberg ER - TY - GEN A1 - Bijleveld, Catrien A1 - Zoutewelle-Terovan, Mioara A1 - Huschek, Doreen A1 - Liefbroer, Aart C. T1 - Criminal careers and demographic outcomes: An introduction to the special issue T2 - Advances in life course research Y1 - 2016 U6 - https://doi.org/10.1016/j.alcr.2016.05.001 SN - 1569-4909 SN - 1879-6974 VL - 28 SP - 1 EP - 5 PB - Elsevier CY - Oxford ER - TY - GEN A1 - Leminen, Alina A1 - Lehtonen, Minna A1 - Bozic, Mirjana A1 - Clahsen, Harald T1 - Editorial: Morphologically Complex Words in the Mind/Brain T2 - Frontiers in human neuroscienc KW - morphology KW - derivation KW - inflection KW - compound KW - L2 KW - dyslexia KW - semantics KW - decomposition Y1 - 2016 U6 - https://doi.org/10.3389/fnhum.2016.00047 SN - 1662-5161 VL - 10 SP - 150 EP - 160 PB - Frontiers Research Foundation CY - Lausanne ER - TY - GEN A1 - Weske, Mathias A1 - Sadiq, Shazia A1 - Soffer, Pnina A1 - Voelzer, Hagen T1 - Preface to BPM 2014 T2 - Information systems Y1 - 2016 U6 - https://doi.org/10.1016/j.is.2015.09.006 SN - 0306-4379 SN - 1873-6076 VL - 56 SP - 233 EP - 234 PB - Elsevier CY - Oxford ER -