TY - JOUR A1 - Gotzner, Nicole A1 - Romoli, Jacopo T1 - Meaning and alternatives JF - Annual review of linguistics N2 - Alternatives and competition in language are pervasive at all levels of linguistic analysis. More specifically, alternatives have been argued to play a prominent role in an ever-growing class of phenomena in the investigation of natural language meaning. In this article, we focus on scalar implicatures, as they are arguably the most paradigmatic case of an alternative-based phenomenon. We first review the main challenge for theories of alternatives, the so-called symmetry problem, and we briefly discuss how it has shaped the different approaches to alternatives. We then turn to two more recent challenges concerning scalar diversity and the inferences of sentences with multiple scalars. Finally, we describe several related alternative-based phenomena and recent conceptual approaches to alternatives. As we discuss, while important progress has been made, much more work is needed both on the theoretical side and on understanding the empirical landscape better. KW - alternatives KW - scalar implicatures KW - symmetry problem KW - focus KW - polarity KW - sensitivity KW - negative strengthening Y1 - 2022 U6 - https://doi.org/10.1146/annurev-linguistics-031220-012013 SN - 2333-9691 SN - 2333-9683 VL - 8 SP - 213 EP - 234 PB - Annual Reviews CY - Palo Alto ER - TY - JOUR A1 - Deusdará-Leal, Karinne A1 - Samprogna Mohor, Guilherme A1 - Cuartas, Luz Adriana A1 - Seluchi, Marcelo E. A1 - Marengo, Jose A. A1 - Zhang, Rong A1 - Broedel, Elisangela A1 - Amore, Diogo de Jesus A1 - Alvalá, Regina C. S. A1 - Cunha, Ana Paula M. A. A1 - Gonçalves, José A. C. T1 - Trends and climate elasticity of streamflow in south-eastern Brazil basins JF - Water N2 - Trends in streamflow, rainfall and potential evapotranspiration (PET) time series, from 1970 to 2017, were assessed for five important hydrological basins in Southeastern Brazil. The concept of elasticity was also used to assess the streamflow sensitivity to changes in climate variables, for annual data and 5-, 10- and 20-year moving averages. Significant negative trends in streamflow and rainfall and significant increasing trend in PET were detected. For annual analysis, elasticity revealed that 1% decrease in rainfall resulted in 1.21-2.19% decrease in streamflow, while 1% increase in PET induced different reductions percentages in streamflow, ranging from 2.45% to 9.67%. When both PET and rainfall were computed to calculate the elasticity, results were positive for some basins. Elasticity analysis considering 20-year moving averages revealed that impacts on the streamflow were cumulative: 1% decrease in rainfall resulted in 1.83-4.75% decrease in streamflow, while 1% increase in PET induced 3.47-28.3% decrease in streamflow. This different temporal response may be associated with the hydrological memory of the basins. Streamflow appears to be more sensitive in less rainy basins. This study provides useful information to support strategic government decisions, especially when the security of water resources and drought mitigation are considered in face of climate change. KW - runoff KW - precipitation KW - potential evapotranspiration KW - Pettitt test KW - sensitivity Y1 - 2022 U6 - https://doi.org/10.3390/w14142245 SN - 2073-4441 VL - 14 IS - 14 PB - MDPI CY - Basel ER - TY - GEN A1 - Aloui, Ali A1 - Tayech, Amel A1 - Arbi Mejri, Mohamed A1 - Makhlouf, Issam A1 - Clark, Cain C. T. A1 - Granacher, Urs A1 - Zouhal, Hassane A1 - Ben Abderrahman, Abderraouf T1 - Reliability and Validity of a New Taekwondo-Specific Change-of-Direction Speed Test With Striking Techniques in Elite Taekwondo Athletes: A Pilot Study T2 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe N2 - The purpose of this study was to examine the test-retest reliability, and convergent and discriminative validity of a new taekwondo-specific change-of-direction (COD) speed test with striking techniques (TST) in elite taekwondo athletes. Twenty (10 males and 10 females) elite (athletes who compete at national level) and top-elite (athletes who compete at national and international level) taekwondo athletes with an average training background of 8.9 ± 1.3 years of systematic taekwondo training participated in this study. During the two-week test-retest period, various generic performance tests measuring COD speed, balance, speed, and jump performance were carried out during the first week and as a retest during the second week. Three TST trials were conducted with each athlete and the best trial was used for further analyses. The relevant performance measure derived from the TST was the time with striking penalty (TST-TSP). TST-TSP performances amounted to 10.57 ± 1.08 s for males and 11.74 ± 1.34 s for females. The reliability analysis of the TST performance was conducted after logarithmic transformation, in order to address the problem of heteroscedasticity. In both groups, the TST demonstrated a high relative test-retest reliability (intraclass correlation coefficients and 90% compatibility limits were 0.80 and 0.47 to 0.93, respectively). For absolute reliability, the TST’s typical error of measurement (TEM), 90% compatibility limits, and magnitudes were 4.6%, 3.4 to 7.7, for males, and 5.4%, 3.9 to 9.0, for females. The homogeneous sample of taekwondo athletes meant that the TST’s TEM exceeded the usual smallest important change (SIC) with 0.2 effect size in the two groups. The new test showed mostly very large correlations with linear sprint speed (r = 0.71 to 0.85) and dynamic balance (r = −0.71 and −0.74), large correlations with COD speed (r = 0.57 to 0.60) and vertical jump performance (r = −0.50 to −0.65), and moderate correlations with horizontal jump performance (r = −0.34 to −0.45) and static balance (r = −0.39 to −0.44). Top-elite athletes showed better TST performances than elite counterparts. Receiver operating characteristic analysis indicated that the TST effectively discriminated between top-elite and elite taekwondo athletes. In conclusion, the TST is a valid, and sensitive test to evaluate the COD speed with taekwondo specific skills, and reliable when considering ICC and TEM. Although the usefulness of the TST is questioned to detect small performance changes in the present population, the TST can detect moderate changes in taekwondo-specific COD speed. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 789 KW - taekwondo-specific testing KW - sport-specific performance KW - striking combat sports KW - sensitivity KW - taekwondo electronic scoring system Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-563192 SN - 1866-8364 SP - 1 EP - 15 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Aloui, Ali A1 - Tayech, Amel A1 - Arbi Mejri, Mohamed A1 - Makhlouf, Issam A1 - Clark, Cain C. T. A1 - Granacher, Urs A1 - Zouhal, Hassane A1 - Ben Abderrahman, Abderraouf T1 - Reliability and Validity of a New Taekwondo-Specific Change-of-Direction Speed Test With Striking Techniques in Elite Taekwondo Athletes: A Pilot Study JF - Frontiers in Physiology N2 - The purpose of this study was to examine the test-retest reliability, and convergent and discriminative validity of a new taekwondo-specific change-of-direction (COD) speed test with striking techniques (TST) in elite taekwondo athletes. Twenty (10 males and 10 females) elite (athletes who compete at national level) and top-elite (athletes who compete at national and international level) taekwondo athletes with an average training background of 8.9 ± 1.3 years of systematic taekwondo training participated in this study. During the two-week test-retest period, various generic performance tests measuring COD speed, balance, speed, and jump performance were carried out during the first week and as a retest during the second week. Three TST trials were conducted with each athlete and the best trial was used for further analyses. The relevant performance measure derived from the TST was the time with striking penalty (TST-TSP). TST-TSP performances amounted to 10.57 ± 1.08 s for males and 11.74 ± 1.34 s for females. The reliability analysis of the TST performance was conducted after logarithmic transformation, in order to address the problem of heteroscedasticity. In both groups, the TST demonstrated a high relative test-retest reliability (intraclass correlation coefficients and 90% compatibility limits were 0.80 and 0.47 to 0.93, respectively). For absolute reliability, the TST’s typical error of measurement (TEM), 90% compatibility limits, and magnitudes were 4.6%, 3.4 to 7.7, for males, and 5.4%, 3.9 to 9.0, for females. The homogeneous sample of taekwondo athletes meant that the TST’s TEM exceeded the usual smallest important change (SIC) with 0.2 effect size in the two groups. The new test showed mostly very large correlations with linear sprint speed (r = 0.71 to 0.85) and dynamic balance (r = −0.71 and −0.74), large correlations with COD speed (r = 0.57 to 0.60) and vertical jump performance (r = −0.50 to −0.65), and moderate correlations with horizontal jump performance (r = −0.34 to −0.45) and static balance (r = −0.39 to −0.44). Top-elite athletes showed better TST performances than elite counterparts. Receiver operating characteristic analysis indicated that the TST effectively discriminated between top-elite and elite taekwondo athletes. In conclusion, the TST is a valid, and sensitive test to evaluate the COD speed with taekwondo specific skills, and reliable when considering ICC and TEM. Although the usefulness of the TST is questioned to detect small performance changes in the present population, the TST can detect moderate changes in taekwondo-specific COD speed. KW - taekwondo-specific testing KW - sport-specific performance KW - striking combat sports KW - sensitivity KW - taekwondo electronic scoring system Y1 - 2022 U6 - https://doi.org/10.3389/fphys.2022.774546 SN - 1664-042X VL - 13 SP - 1 EP - 15 PB - Frontiers CY - Lausanne, Schweiz ER - TY - JOUR A1 - Tawfik, Ahmed Y. A1 - Ondrak, Robert A1 - Winterleitner, Gerd A1 - Mutti, Maria T1 - Source rock evaluation and petroleum system modeling of the East Beni Suef Basin, north Eastern Desert, Egypt JF - Journal of African earth sciences N2 - This study deals with the East Beni Suef Basin (Eastern Desert, Egypt) and aims to evaluate the source-generative potential, reconstruct the burial and thermal history, examine the most influential parameters on thermal maturity modeling, and improve on the models already published for the West Beni Suef to ultimately formulate a complete picture of the whole basin evolution. Source rock evaluation was carried out based on TOC, Rock-Eval pyrolysis, and visual kerogen petrography analyses. Three kerogen types (II, II/III, and III) are distinguished in the East Beni Suef Basin, where the Abu Roash "F" Member acts as the main source rock with good to excellent source potential, oil-prone mainly type II kerogen, and immature to marginal maturity levels. The burial history shows four depositional and erosional phases linked with the tectonic evolution of the basin. A hiatus (due to erosion or non-deposition) has occurred during the Late Eocene-Oligocene in the East Beni Suef Basin, while the West Beni Suef Basin has continued subsiding. Sedimentation began later (Middle to Late Albian) with lower rates in the East Beni Suef Basin compared with the West Beni Suef Basin (Early Albian). The Abu Roash "F" source rock exists in the early oil window with a present-day transformation ratio of about 19% and 21% in the East and West Beni Suef Basin, respectively, while the Lower Kharita source rock, which is only recorded in the West Beni Suef Basin, has reached the late oil window with a present-day transformation ratio of about 70%. The magnitude of erosion and heat flow have proportional and mutual effects on thermal maturity. We present three possible scenarios of basin modeling in the East Beni Suef Basin concerning the erosion from the Apollonia and Dabaa formations. Results of this work can serve as a basis for subsequent 2D and/or 3D basin modeling, which are highly recommended to further investigate the petroleum system evolution of the Beni Suef Basin. KW - source rock evaluation KW - Kerogen petrography KW - basin modeling KW - sensitivity KW - analysis KW - Beni Suef Basin KW - Egypt Y1 - 2022 U6 - https://doi.org/10.1016/j.jafrearsci.2022.104575 SN - 1464-343X SN - 1879-1956 VL - 193 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Bondü, Rebecca A1 - Bilgin, Ayten A1 - Warschburger, Petra T1 - Justice sensitivity and rejection sensitivity as predictors and outcomes of eating disorder pathology BT - a 5-year longitudinal study JF - The international journal of eating disorders N2 - Objective: Rejection sensitivity and justice sensitivity are personality traits that are characterized by frequent perceptions and intense adverse responses to negative social cues. Whereas there is good evidence for associations between rejection sensitivity, justice sensitivity, and internalizing problems, no longitudinal studies have investigated their association with eating disorder (ED) pathology so far. Thus, the present study examined longitudinal relations between rejection sensitivity, justice sensitivity, and ED pathology. Method: Participants (N = 769) reported on their rejection sensitivity, justice sensitivity, and ED pathology at 9-19 (T1), 11-21 (T2), and 14-22 years of age (T3). Results: Latent cross-lagged models showed longitudinal associations between ED pathology and anxious rejection sensitivity, observer and victim justice sensitivity. T1 and T2 ED pathology predicted higher T2 and T3 anxious rejection sensitivity, respectively. In turn, T2 anxious rejection sensitivity predicted more T3 ED pathology. T1 observer justice sensitivity predicted more T2 ED pathology, which predicted higher T3 observer justice sensitivity. Furthermore, T1 ED pathology predicted higher T2 victim justice sensitivity. Discussion: Rejection sensitivity-particularly anxious rejection sensitivity-and justice sensitivity may be involved in the maintenance or worsening of ED pathology and should be considered by future research and in prevention and treatment of ED pathology. Also, mental health problems may increase rejection sensitivity and justice sensitivity traits in the long term. KW - eating disorder pathology KW - justice sensitivity KW - longitudinal KW - rejection KW - sensitivity Y1 - 2020 U6 - https://doi.org/10.1002/eat.23273 SN - 0276-3478 SN - 1098-108X VL - 53 IS - 6 SP - 926 EP - 936 PB - Wiley CY - New York, NY ER - TY - JOUR A1 - Stegenwallner-Schütz, Maja A1 - Adani, Flavia T1 - Production of referring expressions by children with ASD BT - effects of referent accessibility and working memory capacity JF - Language acquisition : a journal of developmental linguistics N2 - This study examines the discourse basis for referent accessibility and its relation to the choice of referring expressions by children with Autism Spectrum Disorder (ASD) and typically developing children. The aim is to delineate how the linguistic and extra-linguistic context affects referent accessibility to the speaker. The study also examines the degree to which accessibility effects are modulated by cognitive factors such as working memory capacity. In the study, the contrast levels between the referent and a competitor (one contrast/two contrasts) and the syntactic prominence of the referent (subject/object position in the preceding question) were manipulated in an elicited production task. The results provide evidence that the referring expressions of children with ASD correlate with the discourse status of referents to a similar extent as in typically developing controls. All children were more likely to refer with lexical NPs to referents that contrasted on two levels with a highly prominent competitor, compared to referents that contrasted on one level. They were also more likely to produce pronouns for referents previously mentioned in the subject than the object position. The effect of both discourse factors was modulated by the age and working memory capacity of the children with and without ASD. Accordingly, the study suggests that children with ASD do not generally differ from children with typical development in their referential choices when the discourse status of a referent allows them to model the referent's accessibility from their own discourse perspective in a way that is modulated by working memory capacity. KW - attention KW - autism spektrum disorders KW - choice KW - communication KW - discourse KW - information KW - language KW - pronouns KW - sensitivity KW - speakers Y1 - 2020 U6 - https://doi.org/10.1080/10489223.2020.1769625 SN - 1048-9223 SN - 1532-7817 VL - 27 IS - 3 SP - 276 EP - 305 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - GEN A1 - Chaabene, Helmi A1 - Negra, Yassine A1 - Bouguezzi, Raja A1 - Capranica, Laura A1 - Franchini, Emerson A1 - Prieske, Olaf A1 - Hbacha, Hamdi A1 - Granacher, Urs T1 - Tests for the Assessment of Sport-Specific Performance in Olympic Combat Sports BT - A Systematic Review With Practical Recommendations T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - The regular monitoring of physical fitness and sport-specific performance is important in elite sports to increase the likelihood of success in competition. This study aimed to systematically review and to critically appraise the methodological quality, validation data, and feasibility of the sport-specific performance assessment in Olympic combat sports like amateur boxing, fencing, judo, karate, taekwondo, and wrestling. A systematic search was conducted in the electronic databases PubMed, Google-Scholar, and Science-Direct up to October 2017. Studies in combat sports were included that reported validation data (e.g., reliability, validity, sensitivity) of sport-specific tests. Overall, 39 studies were eligible for inclusion in this review. The majority of studies (74%) contained sample sizes <30 subjects. Nearly, 1/3 of the reviewed studies lacked a sufficient description (e.g., anthropometrics, age, expertise level) of the included participants. Seventy-two percent of studies did not sufficiently report inclusion/exclusion criteria of their participants. In 62% of the included studies, the description and/or inclusion of a familiarization session (s) was either incomplete or not existent. Sixty-percent of studies did not report any details about the stability of testing conditions. Approximately half of the studies examined reliability measures of the included sport-specific tests (intraclass correlation coefficient [ICC] = 0.43–1.00). Content validity was addressed in all included studies, criterion validity (only the concurrent aspect of it) in approximately half of the studies with correlation coefficients ranging from r = −0.41 to 0.90. Construct validity was reported in 31% of the included studies and predictive validity in only one. Test sensitivity was addressed in 13% of the included studies. The majority of studies (64%) ignored and/or provided incomplete information on test feasibility and methodological limitations of the sport-specific test. In 28% of the included studies, insufficient information or a complete lack of information was provided in the respective field of the test application. Several methodological gaps exist in studies that used sport-specific performance tests in Olympic combat sports. Additional research should adopt more rigorous validation procedures in the application and description of sport-specific performance tests in Olympic combat sports. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 436 KW - martial arts KW - validity KW - sensitivity KW - methodological quality KW - specific assessment Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-411959 IS - 436 ER - TY - JOUR A1 - Chaabene, Helmi A1 - Negra, Yassine A1 - Bouguezzi, Raja A1 - Capranica, Laura A1 - Franchini, Emerson A1 - Prieske, Olaf A1 - Hbacha, Hamdi A1 - Granacher, Urs T1 - Tests for the Assessment of Sport-Specific Performance in Olympic Combat Sports BT - A Systematic Review With Practical Recommendations JF - Frontiers in Physiology N2 - The regular monitoring of physical fitness and sport-specific performance is important in elite sports to increase the likelihood of success in competition. This study aimed to systematically review and to critically appraise the methodological quality, validation data, and feasibility of the sport-specific performance assessment in Olympic combat sports like amateur boxing, fencing, judo, karate, taekwondo, and wrestling. A systematic search was conducted in the electronic databases PubMed, Google-Scholar, and Science-Direct up to October 2017. Studies in combat sports were included that reported validation data (e.g., reliability, validity, sensitivity) of sport-specific tests. Overall, 39 studies were eligible for inclusion in this review. The majority of studies (74%) contained sample sizes <30 subjects. Nearly, 1/3 of the reviewed studies lacked a sufficient description (e.g., anthropometrics, age, expertise level) of the included participants. Seventy-two percent of studies did not sufficiently report inclusion/exclusion criteria of their participants. In 62% of the included studies, the description and/or inclusion of a familiarization session (s) was either incomplete or not existent. Sixty-percent of studies did not report any details about the stability of testing conditions. Approximately half of the studies examined reliability measures of the included sport-specific tests (intraclass correlation coefficient [ICC] = 0.43–1.00). Content validity was addressed in all included studies, criterion validity (only the concurrent aspect of it) in approximately half of the studies with correlation coefficients ranging from r = −0.41 to 0.90. Construct validity was reported in 31% of the included studies and predictive validity in only one. Test sensitivity was addressed in 13% of the included studies. The majority of studies (64%) ignored and/or provided incomplete information on test feasibility and methodological limitations of the sport-specific test. In 28% of the included studies, insufficient information or a complete lack of information was provided in the respective field of the test application. Several methodological gaps exist in studies that used sport-specific performance tests in Olympic combat sports. Additional research should adopt more rigorous validation procedures in the application and description of sport-specific performance tests in Olympic combat sports. KW - martial arts KW - validity KW - sensitivity KW - methodological quality KW - specific assessment Y1 - 2018 U6 - https://doi.org/10.3389/fphys.2018.00386 SN - 1664-042X VL - 9 SP - 1 EP - 18 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Markovic, Danijela A1 - Carrizo, Savrina F. A1 - Kaercher, Oskar A1 - Walz, Ariane A1 - David, Jonathan N. W. T1 - Vulnerability of European freshwater catchments to climate change JF - Global change biology N2 - Climate change is expected to exacerbate the current threats to freshwater ecosystems, yet multifaceted studies on the potential impacts of climate change on freshwater biodiversity at scales that inform management planning are lacking. The aim of this study was to fill this void through the development of a novel framework for assessing climate change vulnerability tailored to freshwater ecosystems. The three dimensions of climate change vulnerability are as follows: (i) exposure to climate change, (ii) sensitivity to altered environmental conditions and (iii) resilience potential. Our vulnerability framework includes 1685 freshwater species of plants, fishes, molluscs, odonates, amphibians, crayfish and turtles alongside key features within and between catchments, such as topography and connectivity. Several methodologies were used to combine these dimensions across a variety of future climate change models and scenarios. The resulting indices were overlaid to assess the vulnerability of European freshwater ecosystems at the catchment scale (18 783 catchments). The Balkan Lakes Ohrid and Prespa and Mediterranean islands emerge as most vulnerable to climate change. For the 2030s, we showed a consensus among the applied methods whereby up to 573 lake and river catchments are highly vulnerable to climate change. The anthropogenic disruption of hydrological habitat connectivity by dams is the major factor reducing climate change resilience. A gap analysis demonstrated that the current European protected area network covers <25% of the most vulnerable catchments. Practical steps need to be taken to ensure the persistence of freshwater biodiversity under climate change. Priority should be placed on enhancing stakeholder cooperation at the major basin scale towards preventing further degradation of freshwater ecosystems and maintaining connectivity among catchments. The catchments identified as most vulnerable to climate change provide preliminary targets for development of climate change conservation management and mitigation strategies. KW - catchment connectivity KW - climate change KW - exposure KW - freshwater biodiversity KW - gap analysis KW - resilience KW - sensitivity KW - vulnerability Y1 - 2017 U6 - https://doi.org/10.1111/gcb.13657 SN - 1354-1013 SN - 1365-2486 VL - 23 SP - 3567 EP - 3580 PB - Wiley CY - Hoboken ER - TY - GEN A1 - Olejko, Lydia A1 - Cywiński, P. J. A1 - Bald, Ilko T1 - An ion-controlled four-color fluorescent telomeric switch on DNA origami structures N2 - The folding of single-stranded telomeric DNA into guanine (G) quadruplexes is a conformational change that plays a major role in sensing and drug targeting. The telomeric DNA can be placed on DNA origami nanostructures to make the folding process extremely selective for K+ ions even in the presence of high Na+ concentrations. Here, we demonstrate that the K+-selective G-quadruplex formation is reversible when using a cryptand to remove K+ from the G-quadruplex. We present a full characterization of the reversible switching between single-stranded telomeric DNA and G-quadruplex structures using Förster resonance energy transfer (FRET) between the dyes fluorescein (FAM) and cyanine3 (Cy3). When attached to the DNA origami platform, the G-quadruplex switch can be incorporated into more complex photonic networks, which is demonstrated for a three-color and a four-color FRET cascade from FAM over Cy3 and Cy5 to IRDye700 with G-quadruplex-Cy3 acting as a switchable transmitter. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 254 KW - resonance energy-transfer KW - g-quadruplex KW - quantum dots KW - strand breakage KW - photonic wires KW - 3-color fret KW - nanostructures KW - recognition KW - sensitivity KW - assemblies Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-95831 SP - 10339 EP - 10347 ER - TY - JOUR A1 - Olejko, Lydia A1 - Cywiński, Piotr J. A1 - Bald, Ilko T1 - An ion-controlled four-color fluorescent telomeric switch on DNA origami structures JF - Nanoscale N2 - The folding of single-stranded telomeric DNA into guanine (G) quadruplexes is a conformational change that plays a major role in sensing and drug targeting. The telomeric DNA can be placed on DNA origami nanostructures to make the folding process extremely selective for K+ ions even in the presence of high Na+ concentrations. Here, we demonstrate that the K+-selective G-quadruplex formation is reversible when using a cryptand to remove K+ from the G-quadruplex. We present a full characterization of the reversible switching between single-stranded telomeric DNA and G-quadruplex structures using Förster resonance energy transfer (FRET) between the dyes fluorescein (FAM) and cyanine3 (Cy3). When attached to the DNA origami platform, the G-quadruplex switch can be incorporated into more complex photonic networks, which is demonstrated for a three-color and a four-color FRET cascade from FAM over Cy3 and Cy5 to IRDye700 with G-quadruplex-Cy3 acting as a switchable transmitter. KW - resonance energy-transfer KW - g-quadruplex KW - quantum dots KW - strand breakage KW - photonic wires KW - 3-color fret KW - nanostructures KW - recognition KW - sensitivity KW - assemblies Y1 - 2016 U6 - https://doi.org/10.1039/C6NR00119J SN - 2040-3372 SN - 2040-3364 VL - 8 SP - 10339 EP - 10347 PB - RSC Publ. CY - Cambridge ER - TY - GEN A1 - Feldmann, Johannes A1 - Levermann, Anders T1 - Similitude of ice dynamics against scaling of geometry and physical parameters T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - The concept of similitude is commonly employed in the fields of fluid dynamics and engineering but rarely used in cryospheric research. Here we apply this method to the problem of ice flow to examine the dynamic similitude of isothermal ice sheets in shallow-shelf approximation against the scaling of their geometry and physical parameters. Carrying out a dimensional analysis of the stress balance we obtain dimensionless numbers that characterize the flow. Requiring that these numbers remain the same under scaling we obtain conditions that relate the geometric scaling factors, the parameters for the ice softness, surface mass balance and basal friction as well as the ice-sheet intrinsic response time to each other. We demonstrate that these scaling laws are the same for both the (two-dimensional) flow-line case and the three-dimensional case. The theoretically predicted ice-sheet scaling behavior agrees with results from numerical simulations that we conduct in flow-line and three-dimensional conceptual setups. We further investigate analytically the implications of geometric scaling of ice sheets for their response time. With this study we provide a framework which, under several assumptions, allows for a fundamental comparison of the ice-dynamic behavior across different scales. It proves to be useful in the design of conceptual numerical model setups and could also be helpful for designing laboratory glacier experiments. The concept might also be applied to real-world systems, e.g., to examine the response times of glaciers, ice streams or ice sheets to climatic perturbations. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 564 KW - grounding line motion KW - full-stokes model KW - West Antarctica KW - sheet models KW - Pine Island KW - stream-B KW - shelf KW - flow KW - sensitivity KW - collapse Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-412441 SN - 1866-8372 IS - 564 SP - 1753 EP - 1769 ER - TY - GEN A1 - Krause, Helena A1 - Bosch, Sina A1 - Clahsen, Harald T1 - Morphosyntax in the bilingual mental lexicon BT - an experimental study of strong stems in German T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - Although morphosyntax has been identified as a major source of difficulty for adult (nonnative) language learners, most previous studies have examined a limited set of largely affix-based phenomena. Little is known about word-based morphosyntax in late bilinguals and of how morphosyntax is represented and processed in a nonnative speaker's lexicon. To address these questions, we report results from two behavioral experiments investigating stem variants of strong verbs in German (which encode features such as tense, person, and number) in groups of advanced adult learners as well as native speakers of German. Although the late bilinguals were highly proficient in German, the results of a lexical priming experiment revealed clear native-nonnative differences. We argue that lexical representation and processing relies less on morphosyntactic information in a nonnative than in a native language. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 520 KW - morphological structure KW - 2nd-language grammar KW - inflected nouns KW - ER-FMRI KW - representation KW - sensitivity KW - violations KW - acquisition KW - agreement KW - learners Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-414431 IS - 520 ER - TY - GEN A1 - Krause, Helena A1 - Bosch, Sina A1 - Clahsen, Harald T1 - Morphosyntax in the bilingual mental lexicon BT - an experimental study of strong stems in German T2 - Postprints der Universität Potsdam Humanwissenschaftliche Reihe N2 - Although morphosyntax has been identified as a major source of difficulty for adult (nonnative) language learners, most previous studies have examined a limited set of largely affix-based phenomena. Little is known about word-based morphosyntax in late bilinguals and of how morphosyntax is represented and processed in a nonnative speaker's lexicon. To address these questions, we report results from two behavioral experiments investigating stem variants of strong verbs in German (which encode features such as tense, person, and number) in groups of advanced adult learners as well as native speakers of German. Although the late bilinguals were highly proficient in German, the results of a lexical priming experiment revealed clear native-nonnative differences. We argue that lexical representation and processing relies less on morphosyntactic information in a nonnative than in a native language. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 528 KW - morphological structure KW - 2nd-language grammar KW - inflected nouns KW - ER-FMRI KW - representation KW - sensitivity KW - violations KW - acquisition KW - agreement KW - learners Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-415478 SN - 1866-8364 IS - 528 ER - TY - GEN A1 - Inal, Sahika A1 - Kölsch, Jonas D. A1 - Sellrie, Frank A1 - Schenk, Jörg A. A1 - Wischerhoff, Erik A1 - Laschewsky, André A1 - Neher, Dieter T1 - A water soluble fluorescent polymer as a dual colour sensor for temperature and a specific protein N2 - We present two thermoresponsive water soluble copolymers prepared via free radical statistical copolymerization of N-isopropylacrylamide (NIPAm) and of oligo(ethylene glycol) methacrylates (OEGMAs), respectively, with a solvatochromic 7-(diethylamino)-3-carboxy-coumarin (DEAC)- functionalized monomer. In aqueous solutions, the NIPAm-based copolymer exhibits characteristic changes in its fluorescence profile in response to a change in solution temperature as well as to the presence of a specific protein, namely an anti-DEAC antibody. This polymer emits only weakly at low temperatures, but exhibits a marked fluorescence enhancement accompanied by a change in its emission colour when heated above its cloud point. Such drastic changes in the fluorescence and absorbance spectra are observed also upon injection of the anti-DEAC antibody, attributed to the specific binding of the antibody to DEAC moieties. Importantly, protein binding occurs exclusively when the polymer is in the well hydrated state below the cloud point, enabling a temperature control on the molecular recognition event. On the other hand, heating of the polymer–antibody complexes releases a fraction of the bound antibody. In the presence of the DEAC-functionalized monomer in this mixture, the released antibody competitively binds to the monomer and the antibody-free chains of the polymer undergo a more effective collapse and inter-aggregation. In contrast, the emission properties of the OEGMA-based analogous copolymer are rather insensitive to the thermally induced phase transition or to antibody binding. These opposite behaviours underline the need for a carefully tailored molecular design of responsive polymers aimed at specific applications, such as biosensing. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 249 KW - intramolecular charge-transfer KW - phase-transitions KW - responsive polymers KW - sensitivity KW - thermometer KW - dyes KW - modulation KW - assemblies KW - antibodies KW - binding Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-95336 SP - 6373 EP - 6381 ER -