TY  - JOUR
A1  - Pearson, Leanne A.
A1  - Dittmann, Elke
A1  - Mazmouz, Rabia
A1  - Ongley, Sarah E.
A1  - Neilan, Brett A.
T1  - The genetics, biosynthesis and regulation of toxic specialized metabolites of cyanobacteria
JF  - Harmful algae
N2  - The production of toxic metabolites by cyanobacterial blooms represents a significant threat to the health of humans and ecosystems worldwide. Here we summarize the current state of the knowledge regarding the genetics, biosynthesis and regulation of well-characterized cyanotoxins, including the microcystins, nodularin, cylindrospermopsin, saxitoxins and antitoxins, as well as the lesser-known marine toxins (e.g. lyngbyatoxin, aplysiatoxin, jamaicamides, barbamide, curacin, hectochlorin and apratoxins). (C) 2015 Elsevier B.V. All rights reserved.
KW  - Cyanobacteria
KW  - Cyanotoxins
KW  - Specialized metabolites
KW  - Genetics
KW  - Biosynthesis
KW  - Regulation
Y1  - 2016
U6  - https://doi.org/10.1016/j.hal.2015.11.002
SN  - 1568-9883
SN  - 1878-1470
VL  - 54
SP  - 98
EP  - 111
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Neilan, Brett A.
A1  - Pearson, Leanne A.
A1  - Münchhoff, Julia
A1  - Moffitt, Michelle C.
A1  - Dittmann-Thünemann, Elke
T1  - Environmental conditions that influence toxin biosynthesis in cyanobacteria
JF  - Environmental microbiology
N2  - Over the past 15 years, the genetic basis for production of many cyanobacterial bioactive compounds has been described. This knowledge has enabled investigations into the environmental factors that regulate the production of these toxins at the molecular level. Such molecular or systems level studies are also likely to reveal the physiological role of the toxin and contribute to effective water resource management. This review focuses on the environmental regulation of some of the most relevant cyanotoxins, namely the microcystins, nodularin, cylindrospermopsin, saxitoxins, anatoxins and jamaicamides.
Y1  - 2013
U6  - https://doi.org/10.1111/j.1462-2920.2012.02729.x
SN  - 1462-2912
VL  - 15
IS  - 5
SP  - 1239
EP  - 1253
PB  - Wiley-Blackwell
CY  - Hoboken
ER  -