TY - GEN A1 - Köhl, Karin I. A1 - Basler, Georg A1 - Lüdemann, Alexander A1 - Selbig, Joachim A1 - Walther, Dirk T1 - A plant resource and experiment management system based on the Golm Plant Database as a basic tool for omics research T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - Background: For omics experiments, detailed characterisation of experimental material with respect to its genetic features, its cultivation history and its treatment history is a requirement for analyses by bioinformatics tools and for publication needs. Furthermore, meta-analysis of several experiments in systems biology based approaches make it necessary to store this information in a standardised manner, preferentially in relational databases. In the Golm Plant Database System, we devised a data management system based on a classical Laboratory Information Management System combined with web-based user interfaces for data entry and retrieval to collect this information in an academic environment. Results: The database system contains modules representing the genetic features of the germplasm, the experimental conditions and the sampling details. In the germplasm module, genetically identical lines of biological material are generated by defined workflows, starting with the import workflow, followed by further workflows like genetic modification (transformation), vegetative or sexual reproduction. The latter workflows link lines and thus create pedigrees. For experiments, plant objects are generated from plant lines and united in so-called cultures, to which the cultivation conditions are linked. Materials and methods for each cultivation step are stored in a separate ACCESS database of the plant cultivation unit. For all cultures and thus every plant object, each cultivation site and the culture's arrival time at a site are logged by a barcode-scanner based system. Thus, for each plant object, all site-related parameters, e. g. automatically logged climate data, are available. These life history data and genetic information for the plant objects are linked to analytical results by the sampling module, which links sample components to plant object identifiers. This workflow uses controlled vocabulary for organs and treatments. Unique names generated by the system and barcode labels facilitate identification and management of the material. Web pages are provided as user interfaces to facilitate maintaining the system in an environment with many desktop computers and a rapidly changing user community. Web based search tools are the basis for joint use of the material by all researchers of the institute. Conclusion: The Golm Plant Database system, which is based on a relational database, collects the genetic and environmental information on plant material during its production or experimental use at the Max-Planck-Institute of Molecular Plant Physiology. It thus provides information according to the MIAME standard for the component 'Sample' in a highly standardised format. The Plant Database system thus facilitates collaborative work and allows efficient queries in data analysis for systems biology research. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 830 KW - microarray data KW - arabidopsis KW - information Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-427595 IS - 830 ER - TY - GEN A1 - Höhle, Barbara A1 - Hörnig, Robin A1 - Weskott, Thomas A1 - Knauf, Selene A1 - Krüger, Agnes T1 - Effects of focus and definiteness on children's word order BT - evidence from German five-year-olds' reproductions of double object constructions T2 - Postprints der Universität Potsdam Humanwissenschaftliche Reihe N2 - Two experiments tested how faithfully German children aged 4; 5 to 5; 6 reproduce ditransitive sentences that are unmarked or marked with respect to word order and focus (Exp1) or definiteness (Exp2). Adopting an optimality theory (OT) approach, it is assumed that in the German adult grammar word order is ranked lower than focus and definiteness. Faithfulness of children's reproductions decreased as markedness of inputs increased; unmarked structures were reproduced most faithfully and unfaithful outputs had most often an unmarked form. Consistent with the OT proposal, children were more tolerant against inputs marked for word order than for focus; in conflict with the proposal, children were less tolerant against inputs marked for word order than for definiteness. Our results suggest that the linearization of objects in German double object constructions is affected by focus and definiteness, but that prosodic principles may have an impact on the position of a focused constituent. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 511 KW - indefinite articles KW - preschool-children KW - information KW - animacy KW - acquisition KW - constraints KW - sentences KW - language KW - grammar KW - stress Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-415695 SN - 1866-8364 IS - 511 ER - TY - THES A1 - Knorz, Marc Emanuel T1 - Qualitätsmanagement im organisatorischen Wandel : die Rolle von Information und Kommunikation in Qualitätsmanagement-Systemen T1 - Quality management in organizational change : the role of information and communication in quality management systems N2 - 1. Teil A – Theoretische Grundlegung der Arbeit Die wissenschaftliche Arbeit beginnt mit der Darstellung der Problemstellung und der Zielsetzung der wissenschaftlichen Arbeit. Es wird deutlich aufgezeigt werden, dass sich die Lehre des Qualitätsmanagements (QM) nur sehr unzureichend mit den sozialen Aspekten der Information & Kommunikation (I&K) und dem organisatorischen Wandel beschäftigt hat. Aus diesen beiden Unterkapiteln werden die Forschungsfragen abgeleitet und der weitere Aufbau der Arbeit konstruiert. (Kapitel 1). Aufgrund der Problemstellung startet das zweite Kapitel im Rahmen der theoretischen Grundlagen mit der sozialen Systemtheorie. Die Entscheidung für die soziale Systemtheorie wird begründet. Im Zusammenhang mit den sozialen Aspekten der I&K werden die relevanten Erkenntnisbeiträge der sozialen Systemtheorien als einzelne Komponenten vorgestellt. Diese Komponenten werden dann zu einem systemtheoretischen I&K-Modell (SEM) zusammengefügt. (Kapitel 2). Damit die beiden Disziplinen QM und soziale Systemtheorie miteinander verbunden werden können, bedarf es im dritten Kapitel der Dissertation einer Vorstellung der dafür notwendigen und relevanten Inhalte des QM. Im Zuge der Vorstellung der Inhalte des QM werden diese bereits mit der sozialen Systemtheorie verknüpft, um damit aufzuzeigen, wie QMS durch I&K existieren und operieren (Kapitel 3). Das vierte Kapitel verbindet dann die beiden Disziplinen QM und soziale Systemtheorie miteinander, wodurch ein systemtheoretisches QM-Modell (SQM) entsteht. Dieses Modell erklärt den Zusammenhang von QM, I&K und organisatorischem Wandel(Kapitel 4).   2. Teil B – Empirische Untersuchung Für die empirische Untersuchung wird in Kapitel fünf das allgemeine Forschungsdesign hergeleitet werden. Darauf folgt die Vorstellung des Aufbaus und der Abfolge von Interviews und eines Fragebogens (Kapitel 5). Das sechste Kapitel erklärt die Zielsetzung, Hintergrund und Methodik der Experteninterviews mit den Qualitätsmanagementbeauftragten (QMB) und unter-sucht die gängige Praxis des QM bzgl. der sozialen Aspekte der I&K. (Kapitel 6). Das Kapitel sieben erklärt die Zielsetzung, Hintergrund und Methodik der Interviews mit den Unternehmen der Best-Practise (BP). (Kapitel 7). Im Kapitel acht werden die Ursache und Wirkung der sozialen Aspekte der I&K über die Unternehmenskultur im Rahmen eines QMS dargestellt. (Kapitel 8). Im Kapitel neun erfolgt ein Resümee der empirischen Untersuchungen. Die Ergebnisse der empirischen Untersuchungen werden kritisch gewürdigt. Des Weiteren wird aufgezeigt, welcher weitere empirische Forschungsbedarf aufgedeckt wurde.(Kapitel 9). 3. Teil C - Abschluss Der Schlussteil der Arbeit beginnt mit dem zehnten Kapitel durch die Herleitung und Begründung von Verbesserungspotentialen und Handlungsempfehlungen für die Praxis im QM.(Kapitel 10). Im elften Kapitel erfolgt die Beantwortung der Forschungsfragen und der kritischen Würdigung der generierten Erkenntnisse.(Kapitel 11). Im zwölften Kapitel endet die Arbeit mit einem Ausblick auf weiteren Forschungsbedarf, welcher durch das Ergebnis dieser Arbeit entstanden ist (Kapitel 12). N2 - 1. Part A – Theoretical Basis The scientific work starts with the description of the problem and the objective of the scientific work. It will be clearly illustrated, that the science of quality management (QM) is still insufficient take care about the social aspects of information & communication (I&K)and the organizational change. The contents of this chapter are used for the research questions and the structure of the thesis. (Chapter 1) Due to the scientific problem the second chapter is starting with the social system theory as the theoretical basis. The decision and the reasons for the social system theory will be explained. The connection of the social aspects of I&K and the social system theory leads to a system-theoretical I&K model (SEM). (Chapter 2) The necessary contents of QM will be shown in this chapter to connect the disciplines QM and social system theory. The contents of the quality management will be analyzed with the social system theory. The result is an understanding how quality management systems (QMS) are existing and operating with I&K. (Chapter 3) The last chapter in part A is connecting the disciplines QM and social system theory. The result is a system-theoretical QM model (SQM). The SQM is explaining the connection of QM, I&K and the organizational change in QMS. (Chapter 4) 2. Part B – Empirical Investigation The general research design for the empirical investigation is explained in chapter five. Followed by the explanation for the structure and the sequence of the interviews and a questionnaire. (Chapter 5) Chapter six is explaining the objective, background and method of the expert interviews with the quality management representatives (QMB) and is analyzing the common practice of QM regarding the social aspects of I&K. (Chapter 6) Chapter seven is explaining the objective, background and method of the interviews with the best practice companies. (Chapter 7) Within the framework of the corporate culture the cause and effect of the social aspect of I&K in QMS will be explained. (Chapter 8) Chapter nine shows the result and a critical appraisal of all empirical investigations. The need for further empirical investigations will be discussed. (Chapter 9).   3. Part C - Ending The final part of the thesis starts with chapter ten. This chapter shows the potential for improvement and recommendations for actions in the practice of QM. (Chapter 10) The research questions are going to be answered in this chapter and the generated results will be critical discussed. (Chapter 11) The thesis is ending in chapter twelve with an outlook for future research requirements. (Chapter 12) KW - Qualitätsmanagement KW - Information KW - Kommunikation KW - qualitymanagement KW - information KW - communication Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-71190 ER -