TY  - THES
A1  - Maier, Natalia
T1  - Aufbau eines Testsystems zum Nachweis von Ethylglucuronid (EtG) in Haaren
Y1  - 2016
ER  - 
TY  - JOUR
A1  - Kaba, Hani E. J.
A1  - Maier, Natalia
A1  - Schliebe-Ohler, Nicole
A1  - Mayer, Yvonne
A1  - Mueller, Peter P.
A1  - van den Heuvel, Joop
A1  - Schuchhardt, Johannes
A1  - Hanack, Katja
A1  - Bilitewski, Ursula
T1  - Identification of whole pathogenic cells by monoclonal antibodies generated against a specific peptide from an immunogenic cell wall protein
JF  - Journal of microbiological methods
N2  - We selected the immunogenic cell wall beta-(1,3)-glucosyltransferase Bgl2p from Candida albicans as a target protein for the production of antibodies. We identified a unique peptide sequence in the protein and generated monoclonal anti- C. albicans Bgl2p antibodies, which bound in particular to whole C. albicans cells.
KW  - Candida
KW  - Diagnostics
KW  - Flow cytometry
KW  - Peptides
KW  - Bgl2p
Y1  - 2015
U6  - https://doi.org/10.1016/j.mimet.2014.11.003
SN  - 0167-7012
SN  - 1872-8359
VL  - 108
SP  - 61
EP  - 69
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Holzlöhner, Pamela
A1  - Schliebs, Erik
A1  - Maier, Natalia
A1  - Füner, Jonas
A1  - Micheel, Burkhard
A1  - Heilmann, Katja
T1  - Production of monoclonal camelid antibodies by means of hybridoma technology
T2  - The journal of immunology
Y1  - 2013
SN  - 0022-1767
VL  - 190
PB  - American Assoc. of Immunologists
CY  - Bethesda
ER  - 
TY  - JOUR
A1  - Holzlöhner, Pamela
A1  - Butze, Monique
A1  - Maier, Natalia
A1  - Hebel, Nicole
A1  - Schliebs, Erik
A1  - Micheel, Burkhard
A1  - Fuener, Jonas
A1  - Heidicke, Gabriele
A1  - Hanack, Katja
T1  - Generation of murine monoclonal antibodies with specificity against conventional camelid IgG1 and heavy-chain only IgG2/3
JF  - Veterinary Immunology and Immunopathology
N2  - Camelids possess antibodies with a conventional four-chain structure consisting of two heavy and two light chains (of subclass IgG1) but further they also generate heavy-chain only antibodies (of subclass IgG2 and 3) which are fully functional in antigen binding. In this study subclass-specific murine monoclonal antibodies specific to conventional camelid IgG1 and heavy-chain only IgG2/3 were generated and validated for the use as potent secondary detection reagents. The monoclonal antibodies are able to differentiate between all camelid IgGs, conventional four-chain camelid antibodies (of subclass IgG1) and exclusively heavy chain-only antibodies (of subclasses IgG2 and IgG3). Further these antibodies were used to detect specific immune responses after vaccination of Camelids against bovine corona- and rotavirus strains and different E.coli. and Clostridia - antigens and to identify Erysipelothrix rhusiopathiae infected animals within a herd. The described antibodies are suitable as new secondary agents for the detection of different camelid subclasses and the validation of camelid immune reactions.
KW  - Camelid antibodies
KW  - Heavy-chain only antibodies
KW  - Monoclonal antibodies
KW  - Secondary antibodies
KW  - Vaccination
KW  - Disease monitoring
Y1  - 2018
U6  - https://doi.org/10.1016/j.vetimm.2018.01.006
SN  - 0165-2427
SN  - 1873-2534
VL  - 197
SP  - 1
EP  - 6
PB  - Elsevier
CY  - Amsterdam
ER  -