TY - JOUR A1 - Yamazaki, Yosuke A1 - Stolle, Claudia A1 - Matzka, Jürgen A1 - Liu, Huixin A1 - Tao, Chihiro T1 - Interannual variability of the daytime equatorial ionospheric electric field JF - Journal of geophysical research : Space physics N2 - Understanding the variability of the ionosphere is important for the prediction of space weather and climate. Recent studies have shown that forcing from the lower atmosphere plays a significant role for the short-term (day-to-day) variability of the low-latitude ionosphere. The present study aims to assess the importance of atmospheric forcing for the variability of the daytime equatorial ionospheric electric field on the interannual (year-to-year) time scale. Magnetic field measurements from Huancayo (12.05 degrees S, 75.33 degrees W) are used to augment the equatorial vertical plasma drift velocity (V-Z) measurements from the Jicamarca Unattended Long-term Investigations of the Ionosphere and Atmosphere radar during 2001-2016. V-Z can be regarded as a measure of the zonal electric field. After removing the seasonal variation of similar to 10m/s, midday values of V-Z show an interannual variation of similar to 2m/s with an oscillation period of 2-3years. No evidence of solar cycle influence is found. The Ground-to-topside Atmosphere-Ionosphere model for Aeronomy, which takes into account realistic atmospheric variability below 30km, reproduces the pattern of the observed interannual variation without having to include variable forcing from the magnetosphere. The results indicate that lower atmospheric forcing plays a dominant role for the observed interannual variability of V-Z at 1200 local time. KW - interannual variability KW - plasma drifts KW - equatorial electrojet (EEJ) KW - vertical coupling KW - JULIA KW - GAIA Y1 - 2018 U6 - https://doi.org/10.1029/2017JA025165 SN - 2169-9380 SN - 2169-9402 VL - 123 IS - 5 SP - 4241 EP - 4256 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Yan, Wan A1 - Fang, Liang A1 - Nöchel, Ulrich A1 - Gould, Oliver E. C. A1 - Behl, Marc A1 - Kratz, Karl A1 - Lendlein, Andreas T1 - Investigating the roles of crystallizable and glassy switching segments within multiblock copolymer shape-memory materials JF - MRS Advances N2 - The variation of the molecular architecture of multiblock copolymers has enabled the introduction of functional behaviour and the control of key mechanical properties. In the current study, we explore the synergistic relationship of two structural components in a shape-memory material formed of a multiblock copolymer with crystallizable poly(epsilon-caprolactone) and crystallizable polyfoligo(3S-iso-butylmorpholine-2,5-dione) segments (PCL-PIBMD). The thermal and structural properties of PCL-PIBMD films were compared with PCI.-PU and PMMD-PU investigated by means of DSC, SAXS and WARS measurements. The shape-memory properties were quantified by cyclic, thermomechanical tensile tests, where deformation strains up to 900% were applied for programming PCL-PIBMD films at 50 degrees C. Toluene vapor treatment experiments demonstrated that the temporary shape was fixed mainly by glassy PIBMD domains at strains lower than 600% with the PCL contribution to fixation increasing to 42 +/- 2% at programming strains of 900% This study into the shape-memory mechanism of PCL-PIBMD provides insight into the structure function relation in multiblock copolymers with both crystallizable and glassy switching segments. Y1 - 2018 U6 - https://doi.org/10.1557/adv.2018.590 SN - 2059-8521 VL - 3 IS - 63 SP - 3741 EP - 3749 PB - Cambridge Univ. Press CY - New York ER - TY - JOUR A1 - Yan, Wan A1 - Rudolph, Tobias A1 - Nöchel, Ulrich A1 - Gould, Oliver E. C. A1 - Behl, Marc A1 - Kratz, Karl A1 - Lendlein, Andreas T1 - Reversible actuation of thermoplastic multiblock copolymers with overlapping thermal transitions of crystalline and glassy domains JF - Macromolecules : a publication of the American Chemical Society N2 - Polymeric materials possessing specific features like programmability, high deformability, and easy processability are highly desirable for creating modern actuating systems. In this study, thermoplastic shape-memory polymer actuators obtained by combining crystallizable poly(epsilon-caprolactone) (PCL) and poly(3S-isobutylmorpholin-2,5-dione) (PIBMD) segments in multiblock copolymers are described. We designed these materials according to our hypothesis that the confinement of glassy PIBMD domains present at the upper actuation temperature contribute to the stability of the actuator skeleton, especially at large programming strains. The copolymers have a phase-segregated morphology, indicated by the well-separated melting and glass transition temperatures for PIBMD and PCL, but possess a partially overlapping T-m of PCL and T-g of PIBMD in the temperature interval from 40 to 60 degrees C. Crystalline PIBMD hard domains act as strong physical netpoints in the PIBMD-PCL bulk material enabling high deformability (up to 2000%) and good elastic recoverability (up to 80% at 50 degrees C above T-m,T-PCL). In the programmed thermoplastic actuators a high content of crystallizable PCL actuation domains ensures pronounced thermoreversible shape changes upon repetitive cooling and heating. The programmed actuator skeleton, composed of PCL crystals present at the upper actuation temperature T-high and the remaining glassy PIBMD domains, enabled oriented crystallization upon cooling. The actuation performance of PIBMD-PCL could be tailored by balancing the interplay between actuation and skeleton, but also by varying the quantity of crystalline PIBMD hard domains via the copolymer composition, the applied programming strain, and the choice of T-high. The actuator with 17 mol% PIBMD showed the highest reversible elongation of 11.4% when programmed to a strain of 900% at 50 degrees C. It is anticipated that the presented thermoplastic actuator materials can be applied as modern compression textiles. Y1 - 2018 U6 - https://doi.org/10.1021/acs.macromol.8b00322 SN - 0024-9297 SN - 1520-5835 VL - 51 IS - 12 SP - 4624 EP - 4632 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Yang, Guang A1 - Hu, Rongting A1 - Ding, Hong-ming A1 - Kochovski, Zdravko A1 - Mei, Shilin A1 - Lu, Yan A1 - Ma, Yu-qiang A1 - Chen, Guosong A1 - Jiang, Ming T1 - CO2-switchable response of protein microtubules BT - behaviour and mechanism JF - Materials chemistry frontiers N2 - Recently, we proposed a small molecular inducing ligand strategy to assemble proteins into highly-ordered structures via dual non-covalent interactions, i.e. carbohydrate-protein interaction and dimerization of Rhodamine B. Using this approach, artificial protein microtubules were successfully constructed. In this study, we find that these microtubules exhibit a perfect CO2 responsiveness; assembly and disassembly of these microtubules were nicely controlled by the alternative passage of CO2 and N-2. Upon the injection of CO2, a negative net-charged SBA turns into a neutral or positive net-charged SBA, which elongated, to some extent, the effective distance between SBA and Rhodamine B, resulting in the disassociation of the Rhodamine B dimer. Further experimental and simulation results reveal that the CO2-responsive mechanism differs from that of solubility change of the previously reported CO2-responsive synthetic materials. Y1 - 2018 U6 - https://doi.org/10.1039/c8qm00245b SN - 2052-1537 VL - 2 IS - 9 SP - 1642 EP - 1646 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Yang, Jie A1 - Zhu, Xiaolei A1 - Wolf, Thomas J. A. A1 - Li, Zheng A1 - Nunes, João Pedro Figueira A1 - Coffee, Ryan A1 - Cryan, James P. A1 - Gühr, Markus A1 - Hegazy, Kareem A1 - Heinz, Tony F. A1 - Jobe, Keith A1 - Li, Renkai A1 - Shen, Xiaozhe A1 - Veccione, Theodore A1 - Weathersby, Stephen A1 - Wilkin, Kyle J. A1 - Yoneda, Charles A1 - Zheng, Qiang A1 - Martinez, Todd J. A1 - Centurion, Martin A1 - Wang, Xijie T1 - Imaging CF3I conical intersection and photodissociation dynamics with ultrafast electron diffraction JF - Science N2 - Conical intersections play a critical role in excited-state dynamics of polyatomic molecules because they govern the reaction pathways of many nonadiabatic processes. However, ultrafast probes have lacked sufficient spatial resolution to image wave-packet trajectories through these intersections directly. Here, we present the simultaneous experimental characterization of one-photon and two-photon excitation channels in isolated CF3I molecules using ultrafast gas-phase electron diffraction. In the two-photon channel, we have mapped out the real-space trajectories of a coherent nuclear wave packet, which bifurcates onto two potential energy surfaces when passing through a conical intersection. In the one-photon channel, we have resolved excitation of both the umbrella and the breathing vibrational modes in the CF3 fragment in multiple nuclear dimensions. These findings benchmark and validate ab initio nonadiabatic dynamics calculations. Y1 - 2018 U6 - https://doi.org/10.1126/science.aat0049 SN - 0036-8075 SN - 1095-9203 VL - 361 IS - 6397 SP - 64 EP - 67 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Yannelli, Florencia A. A1 - Karrer, Gerhard A1 - Hall, Rea A1 - Kollmann, Johannes A1 - Heger, Tina T1 - Seed density is more effective than multi-trait limiting similarity in controlling grassland resistance against plant invasions in mesocosms JF - Applied vegetation science : official organ of the International Association for Vegetation Science N2 - QuestionDisturbed areas offer great opportunities for restoring native biodiversity, but they are also prone to invasion by alien plants. Following the limiting similarity hypothesis, we address the question of whether or not similarity of plant functional traits helps developing seed mixtures of native communities with high resistance to invasive species at an early stage of restoration. LocationCentre of Greenhouses and Laboratories Durnast, Technische Universitat Munchen, Freising, Germany. MethodsUsing a system of linear equations, we designed native communities maximizing the similarity between the native and two invasive species according to ten functional traits. We used native grassland plants, two invasive alien species that are often problematic in disturbed areas (i.e., Ambrosia artemisiifolia and Solidago gigantea) and trait information obtained from databases. The two communities were then tested for resistance against establishment of the two invaders separately in a greenhouse experiment. We measured height of the invasive species and above-ground biomass, along with leaf area index, 4 and 8months after sowing respectively. ResultsBoth invasive species were successfully reduced by the native community designed to suppress S. gigantea dominated by small-seeded species. These results could be considered as partial support for the limiting similarity hypothesis. However, given the success of this mixture against both invasive species, suppression was better explained by a seed density effect resulting from the smaller seed mass of the native species included in this mixture. Further, the dominance of a fast-developing competitive species could also contribute to its success. ConclusionsThere was no unequivocal support for the limiting similarity hypothesis in terms of the traits selected. Instead we found that increasing seeding density of native species and selecting species with a fast vegetative development is an effective way to suppress invasive plants during early stages of restoration. If limiting similarity is used to design communities for restoration, early life-history traits should be taken into account. KW - Achillea millefolium KW - Ambrosia artemisiifolia KW - biotic resistance KW - competition KW - density-driven suppression KW - disturbed areas KW - restoration KW - seed mixtures KW - Solidago gigantea Y1 - 2018 U6 - https://doi.org/10.1111/avsc.12373 SN - 1402-2001 SN - 1654-109X VL - 21 IS - 3 SP - 411 EP - 418 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Yaouba, Souaibou A1 - Koch, Andreas A1 - Guantai, Eric M. A1 - Derese, Solomon A1 - Irungu, Beatrice A1 - Heydenreich, Matthias A1 - Yenesew, Abiy T1 - Alkenyl cyclohexanone derivatives from Lannea rivae and Lannea schweinfurthii JF - Phytochemistry letters / Phytochemical Society of Europe N2 - Phytochemical investigation of the CH2Cl2/MeOH (1:1) extract of the roots of Lannea rivae (Chiov) Sacleux (Anacardiaceae) led to the isolation of a new alkenyl cyclohexenone derivative: (4R,6S)-4,6-dihydroxy-6-((Z)-nonadec-14′-en-1-yl)cyclohex-2-en-1-one (1), and a new alkenyl cyclohexanol derivative: (2S*,4R*,5S*)-2,4,5-trihydroxy-2-((Z)-nonadec-14′-en-1-yl)cyclohexanone (2) along with four known compounds, namely epicatechin gallate, taraxerol, taraxerone and β-sitosterol; while the stem bark afforded two known compounds, daucosterol and lupeol. Similar investigation of the roots of Lannea schweinfurthii (Engl.) Engl. led to the isolation of four known compounds: 3-((E)-nonadec-16′-enyl)phenol, 1-((E)-heptadec-14′-enyl)cyclohex-4-ene-1,3-diol, catechin, and 1-((E)-pentadec-12′-enyl)cyclohex-4-ene-1,3-diol. The structures of the isolated compounds were determined by NMR spectroscopy and mass spectrometry. The absolute configuration of compound 1 was established by quantum chemical ECD calculations. In an antibacterial activity assay using the microbroth kinetic method, compound 1 showed moderate activity against Escherichia coli while compound 2 exhibited moderate activity against Staphylococcus aureus. Compound 1 also showed moderate activity against E. coli using the disc diffusion method. The roots extract of L. rivae was notably cytotoxic against both the DU-145 prostate cancer cell line and the Vero mammalian cell line (CC50 = 5.24 and 5.20 μg/mL, respectively). Compound 1 was also strongly cytotoxic against the DU-145 cell line (CC50 = 0.55 μg/mL) but showed no observable cytotoxicity (CC50 > 100 μg/mL) against the Vero cell line. The roots extract of L. rivae and L. schweinfurthii, epicatechin gallate as well as compound 1 exhibited inhibition of carageenan-induced inflammation. KW - Lannea rivae KW - Lannea schweinfurthii KW - Alkenyl cyclohexenone KW - Alkenyl cyclohexanone KW - Anti-inflammatory KW - Cytotoxicity KW - Antimicrobial Y1 - 2017 U6 - https://doi.org/10.1016/j.phytol.2017.12.001 SN - 1874-3900 SN - 1876-7486 VL - 23 SP - 141 EP - 148 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Yarman, Aysu T1 - Electrosynthesized Molecularly Imprinted Polymer for Laccase Using the Inactivated Enzyme as the Target JF - Bulletin of the Korean chemical society N2 - The first molecularly imprinted polymer (MIP) for the recognition of the copper-enzyme laccase was successfully prepared by electropolymerizing scopoletin in the presence of alkaline-inactivated enzyme. Laccase-MIP and the control polymer without laccase (nonimprinted polymer, NIP) were characterized by voltammetry using the redox marker ferricyanide. After electropolymerization, the signals for ferricyanide for both the MIP and the NIP were almost completely suppressed and increased after removal of the target from the polymer layer. Rebinding of both inactivated and active laccase decreased the ferricyanide peak currents to almost equal extent. The relative decrease of signal suppression approached saturation above 10 nM. Furthermore, the surface activity of rebound laccase toward the oxidation of catechol was investigated. The surface activity approached saturation above 10 nM, a value close to the value of the measurements with ferricyanide. Interaction of NIP with laccase brought about a six times smaller signal of catechol oxidation. KW - Molecularly imprinted polymers KW - Biomimetic sensors KW - Laccase KW - Electropolymerization KW - Scopoletin Y1 - 2018 U6 - https://doi.org/10.1002/bkcs.11413 SN - 1229-5949 VL - 39 IS - 4 SP - 483 EP - 488 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Yazmaciyan, Aren A1 - Stolterfoht, Martin A1 - Burn, Paul L. A1 - Lin, Qianqian A1 - Meredith, Paul A1 - Armin, Ardalan T1 - Recombination losses above and below the transport percolation threshold in bulk heterojunction organic solar cells JF - Advanced energy materials N2 - Achieving the highest power conversion efficiencies in bulk heterojunction organic solar cells requires a morphology that delivers electron and hole percolation pathways for optimized transport, plus sufficient donor:acceptor contact area for near unity charge transfer state formation. This is a significant structural challenge, particularly in semiconducting polymer:fullerene systems. This balancing act in the model high efficiency PTB7:PC70BM blend is studied by tuning the donor:acceptor ratio, with a view to understanding the recombination loss mechanisms above and below the fullerene transport percolation threshold. The internal quantum efficiency is found to be strongly correlated to the slower carrier mobility in agreement with other recent studies. Furthermore, second-order recombination losses dominate the shape of the current density-voltage curve in efficient blend combinations, where the fullerene phase is percolated. However, below the charge transport percolation threshold, there is an electric-field dependence of first-order losses, which includes electric-field-dependent photogeneration. In the intermediate regime, the fill factor appears to be limited by both first- and second-order losses. These findings provide additional basic understanding of the interplay between the bulk heterojunction morphology and the order of recombination in organic solar cells. They also shed light on the limitations of widely used transport models below the percolation threshold. KW - bulk heterojunctions KW - charge transport KW - organic solar cells KW - percolation threshold KW - recombination losses Y1 - 2018 U6 - https://doi.org/10.1002/aenm.201703339 SN - 1614-6832 SN - 1614-6840 VL - 8 IS - 18 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Ye, S. -Y. A1 - Kurth, William S. A1 - Hospodarsky, George B. A1 - Persoon, Ann M. A1 - Gurnett, Don A. A1 - Morooka, Michiko A1 - Wahlund, Jan-Erik A1 - Hsu, Hsiang-Wen A1 - Seiss, Martin A1 - Srama, Ralf T1 - Cassini RPWS dust observation near the Janus/Epimetheus orbit JF - Journal of geophysical research : Space physics N2 - During the Ring Grazing orbits near the end of Cassini mission, the spacecraft crossed the equatorial plane near the orbit of Janus/Epimetheus (similar to 2.5 Rs). This region is populated with dust particles that can be detected by the Radio and Plasma Wave Science (RPWS) instrument via an electric field antenna signal. Analysis of the voltage waveforms recorded on the RPWS antennas provides estimations of the density and size distribution of the dust particles. Measured RPWS profiles, fitted with Lorentzian functions, are shown to be mostly consistent with the Cosmic Dust Analyzer, the dedicated dust instrument on board Cassini. The thickness of the dusty ring varies between 600 and 1,000 km. The peak location shifts north and south within 100 km of the ring plane, likely a function of the precession phase of Janus orbit. KW - Saturn KW - dust KW - ring Y1 - 2018 U6 - https://doi.org/10.1029/2017JA025112 SN - 2169-9380 SN - 2169-9402 VL - 123 IS - 6 SP - 4952 EP - 4960 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Ye, Shengyi A1 - Kurth, William S. A1 - Hospodarsky, George B. A1 - Persoon, Ann M. A1 - Sulaiman, Ali H. A1 - Gurnett, Don A. A1 - Morooka, Michiko A1 - Wahlund, Jan-Erik A1 - Hsu, Hsiang-Wen A1 - Sternovsky, Zoltan A1 - Wang, Xu A1 - Horanyi, M. A1 - Seiss, Martin A1 - Srama, Ralf T1 - Dust Observations by the Radio and Plasma Wave Science Instrument During JF - Geophysical research letters N2 - Plain Language Summary Cassini flew through the gap between Saturn and its rings for 22 times before plunging into the atmosphere of Saturn, ending its 20-year mission. The radio and plasma waves instrument on board Cassini helped quantify the dust hazard in this previously unexplored region. The measured density of large dust particles was much lower than expected, allowing high-value science observations during the subsequent Grand Finale orbits. Y1 - 2018 U6 - https://doi.org/10.1029/2018GL078059 SN - 0094-8276 SN - 1944-8007 VL - 45 IS - 19 SP - 10101 EP - 10109 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Yedidya, Asaf T1 - Enlisted History BT - Zeev Jawitz (1847–1924) and the Making of a National Orthodox Wissenschaft des Judentums JF - PaRDES : Zeitschrift der Vereinigung für Jüdische Studien e. V. N2 - Zeev Jawitz (1847–1924) was active in all spheres of culture: history, language, literature and pedagogy, all the while striving for harmonization with the Orthodox outlook. He understood that a people returning to its homeland needed a national culture, one that was both broad and deep, and that the narrow world of the Halakhah would no longer suffice. His main work was the multi-volume Toldot Israel (History of Israel, published 1895–1924) which encompasses Jewish history from its beginning – Patriarchs – until the end of the 19th century. His historical writing, with its emphasis on internal religious Jewish sources, the unity and continuity of Jewish history, and respect of Orthodox principles, comes as an alternative to the historiography of the celebrated historian Heinrich Graetz. The alternative that Jawitz tried to substitute for Wissenschaft des Judentums, was influenced not only by Orthodox ideology, which he supported, but also by his nationalist ideology. He saw himself and his disciples as the “priests of memory,” presenting the true and immanent history and character of the Jewish nation as a platform to the Jewish future in the land of Israel. Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-417808 SP - 79 EP - 101 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Yilmaz, Zafer T1 - Revising the culture of political protest after the gezi uprising in Turkey BT - radical imagination, affirmative resistance, and the new politics of desire and dignity JF - Mediterranean Quarterly N2 - The Gezi uprising can be considered a crucial turning in Turkish politics. As a response to countrywide democratic protests, the Justice and Development Party (AKP) government revived the security state, escalated authoritarian tendencies, and started to organize a nationalist, Islamist, and conservative backlash. This essay argues that the Gezi Park protests revealed both the fragility of the AKP's hegemony and the limits of the dominant political group habitus, which were promoted by the party to consolidate political polarization in favor of the party's hegemony. Moreover, it is argued that the Gezi uprising transformed the culture of political protests in the country and paved the way for the emergence of affirmative resistance, radical imagination, and a new politics of desire and dignity against authoritarian and neoliberal policies. KW - Erdogan KW - Turkish politics KW - democracy KW - authoritarianism KW - AKP Y1 - 2018 U6 - https://doi.org/10.1215/10474552-7003168 SN - 1047-4552 SN - 1527-1935 VL - 29 IS - 3 SP - 55 EP - 77 PB - Duke Univ. Press CY - Durham ER - TY - JOUR A1 - Young, Linda A1 - Ueda, Kiyoshi A1 - Gühr, Markus A1 - Bucksbaum, Philip H. A1 - Simon, Marc A1 - Mukamel, Shaul A1 - Rohringer, Nina A1 - Prince, Kevin C. A1 - Masciovecchio, Claudio A1 - Meyer, Michael A1 - Rudenko, Artem A1 - Rolles, Daniel A1 - Bostedt, Christoph A1 - Fuchs, Matthias A1 - Reis, David A. A1 - Santra, Robin A1 - Kapteyn, Henry A1 - Murnane, Margaret A1 - Ibrahim, Heide A1 - Legare, Francois A1 - Vrakking, Marc A1 - Isinger, Marcus A1 - Kroon, David A1 - Gisselbrecht, Mathieu A1 - Wörner, Hans Jakob A1 - Leone, Stephen R. T1 - Roadmap of ultrafast x-ray atomic and molecular physics JF - Journal of physics : B, Atomic, molecular and optical physics N2 - X-ray free-electron lasers (XFELs) and table-top sources of x-rays based upon high harmonic generation (HHG) have revolutionized the field of ultrafast x-ray atomic and molecular physics, largely due to an explosive growth in capabilities in the past decade. XFELs now provide unprecedented intensity (10(20) W cm(-2)) of x-rays at wavelengths down to similar to 1 Angstrom, and HHG provides unprecedented time resolution (similar to 50 attoseconds) and a correspondingly large coherent bandwidth at longer wavelengths. For context, timescales can be referenced to the Bohr orbital period in hydrogen atom of 150 attoseconds and the hydrogen-molecule vibrational period of 8 femtoseconds; wavelength scales can be referenced to the chemically significant carbon K-edge at a photon energy of similar to 280 eV (44 Angstroms) and the bond length in methane of similar to 1 Angstrom. With these modern x-ray sources one now has the ability to focus on individual atoms, even when embedded in a complex molecule, and view electronic and nuclear motion on their intrinsic scales (attoseconds and Angstroms). These sources have enabled coherent diffractive imaging, where one can image non-crystalline objects in three dimensions on ultrafast timescales, potentially with atomic resolution. The unprecedented intensity available with XFELs has opened new fields of multiphoton and nonlinear x-ray physics where behavior of matter under extreme conditions can be explored. The unprecedented time resolution and pulse synchronization provided by HHG sources has kindled fundamental investigations of time delays in photoionization, charge migration in molecules, and dynamics near conical intersections that are foundational to AMO physics and chemistry. This roadmap coincides with the year when three new XFEL facilities, operating at Angstrom wavelengths, opened for users (European XFEL, Swiss-FEL and PAL-FEL in Korea) almost doubling the present worldwide number of XFELs, and documents the remarkable progress in HHG capabilities since its discovery roughly 30 years ago, showcasing experiments in AMO physics and other applications. Here we capture the perspectives of 17 leading groups and organize the contributions into four categories: ultrafast molecular dynamics, multidimensional x-ray spectroscopies; high-intensity x-ray phenomena; attosecond x-ray science. KW - ultrafast molecular dynamics KW - x-ray spectroscopies and phenomena KW - table-top sources KW - x-ray free-electron lasers KW - attosecond phenomena Y1 - 2018 U6 - https://doi.org/10.1088/1361-6455/aa9735 SN - 0953-4075 SN - 1361-6455 VL - 51 IS - 3 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Yousfi, Alaaeddine A1 - Hewelt, Marcin A1 - Bauer, Christine A1 - Weske, Mathias T1 - Toward uBPMN-Based patterns for modeling ubiquitous business processes JF - IEEE Transactions on Industrial Informatics N2 - Ubiquitous business processes are the new generation of processes that pervade the physical space and interact with their environments using a minimum of human involvement. Although they are now widely deployed in the industry, their deployment is still ad hoc . They are implemented after an arbitrary modeling phase or no modeling phase at all. The absence of a solid modeling phase backing up the implementation generates many loopholes that are stressed in the literature. Here, we tackle the issue of modeling ubiquitous business processes. We propose patterns to represent the recent ubiquitous computing features. These patterns are the outcome of an analysis we conducted in the field of human-computer interaction to examine how the features are actually deployed. The patterns' understandability, ease-of-use, usefulness, and completeness are examined via a user experiment. The results indicate that these four indexes are on the positive track. Hence, the patterns may be the backbone of ubiquitous business process modeling in industrial applications. KW - Ubiquitous business process KW - ubiquitous business process model and notation (uBPMN) KW - ubiquitous business process modeling KW - ubiquitous computing (ubicomp) Y1 - 2017 U6 - https://doi.org/10.1109/TII.2017.2777847 SN - 1551-3203 SN - 1941-0050 VL - 14 IS - 8 SP - 3358 EP - 3367 PB - Inst. of Electr. and Electronics Engineers CY - Piscataway ER - TY - JOUR A1 - Zabihi, Fatemeh A1 - Graff, Patrick A1 - Schumacher, Fabian A1 - Kleuser, Burkhard A1 - Hedtrich, Sarah A1 - Haag, Rainer T1 - Synthesis of poly(lactide-co-glycerol) as a biodegradable and biocompatible polymer with high loading capacity for dermal drug delivery JF - Nanoscale N2 - Due to the low cutaneous bioavailability of tacrolimus (TAC), penetration enhancers are used to improve its penetration into the skin. However, poor loading capacity, non-biodegradability, toxicity, and in some cases inefficient skin penetration are challenging issues that hamper their applications for the dermal TAC delivery. Here we present poly(lactide-co-glycerol) (PLG) as a water soluble, biodegradable, and biocompatible TAC-carrier with high loading capacity (14.5% w/w for TAC) and high drug delivery efficiencies into the skin. PLG was synthesized by cationic ring-opening copolymerization of a mixture of glycidol and lactide and showed 35 nm and 300 nm average sizes in aqueous solutions before and after loading of TAC, respectively. Delivery experiments on human skin, quantified by fluorescence microscopy and LC-MS/MS, showed a high ability for PLG to deposit Nile red and TAC into the stratum corneum and viable epidermis of skin in comparison with Protopic (R) (0.03% w/w, TAC ointment). The cutaneous distribution profile of delivered TAC proved that 80%, 16%, and 4% of the cutaneous drug level was deposited in the stratum corneum, viable epidermis, and upper dermis, respectively. TAC delivered by PLG was able to efficiently decrease the IL-2 and TSLP expressions in human skin models. Taking advantage of the excellent physicochemical and biological properties of PLG, it can be used for efficient dermal TAC delivery and potential treatment of inflammatory skin diseases. Y1 - 2018 U6 - https://doi.org/10.1039/c8nr05536j SN - 2040-3364 SN - 2040-3372 VL - 10 IS - 35 SP - 16848 EP - 16856 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Zakarias, Lilla A1 - Salis, Christos A1 - Wartenburger, Isabell T1 - Transfer effects on spoken sentence comprehension and functional communication after working memory training in stroke aphasia JF - Journal of neurolinguistics : an international journal for the study of brain function in language behavior and experience N2 - Recent treatment protocols have been successful in improving working memory (WM) in individuals with aphasia. However, the evidence to date is small and the extent to which improvements in trained tasks of WM transfer to untrained memory tasks, spoken sentence comprehension, and functional communication is yet poorly understood. To address these issues, we conducted a multiple baseline study with three German-speaking individuals with chronic post stroke aphasia. Participants practised two computerised WM tasks (n-back with pictures and aback with spoken words) four times a week for a month, targeting two WM processes: updating WM representations and resolving interference. All participants showed improvement on at least one measure of spoken sentence comprehension and everyday memory activities. Two of them showed improvement also on measures of WM and functional communication. Our results suggest that WM can be improved through computerised training in chronic aphasia and this can transfer to spoken sentence comprehension and functional communication in some individuals. KW - Aphasia KW - Working memory KW - n-back training KW - Transfer KW - Sentence comprehension KW - Verbal communication Y1 - 2018 U6 - https://doi.org/10.1016/j.jneuroling.2017.12.002 SN - 0911-6044 VL - 48 SP - 47 EP - 63 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Zapata, Sebastian Henao A1 - Cardona, A. A1 - Jaramillo, J. S. A1 - Patino, A. A1 - Valencia, V. A1 - Leon, S. A1 - Mejia, D. A1 - Pardo-Trujillo, A. A1 - Castaneda, J. P. T1 - Cretaceous extensional and compressional tectonics in the Northwestern Andes, prior to the collision with the Caribbean oceanic plateau JF - Gondwana research : international geoscience journal ; official journal of the International Association for Gondwana Research N2 - The Cretaceous units exposed in the northwestern segment of the Colombian Andes preserve the record of extensional and compressional tectonics prior to the collision with Caribbean oceanic terranes. We integrated field, stratigraphic, sedimentary provenance, whole rock geochemistry, Nd isotopes and U-Pb zircon data to understand the Cretaceous tectonostratigraphic and magmatic record of the Colombian Andes. The results suggest that several sedimentary successions including the Abejorral Fm. were deposited on top of the continental basement in an Early Cretaceous backarc basin (150-100 Ma). Between 120 and 100 Ma, the appearance of basaltic and andesitic magmatism (similar to 115-100 Ma), basin deepening, and seafloor spreading were the result of advanced stages of backarc extension. A change to compressional tectonics took place during the Late Cretaceous (100-80 Ma). During this compressional phase, the extended blocks were reincorporated into the margin, closing the former Early Cretaceous backarc basin. Subsequently, a Late Cretaceous volcanic arc was built on the continental margin: as a result, the volcanic rocks of the Quebradagrande Complex were unconformably deposited on top of the faulted and folded rocks of the Abejorral Fm. Between the Late Cretaceous and the Paleocene (80-60 Ma), an arc-continent collision between the Caribbean oceanic plateau and the South-American continental margin deformed the rocks of the Quebradagrande Complex and shut-down the active volcanic arc. Our results suggest an Early Cretaceous extensional event followed by compressional tectonics prior to the collision with the Caribbean oceanic plateau. (C) 2019 International Association for Gondwana Research. Published by Elsevier B.V. All rights reserved. KW - Northern Andes KW - Paleogeography KW - Cretaceous KW - Extension KW - Convergent margins KW - Provenance Y1 - 2018 U6 - https://doi.org/10.1016/j.gr.2018.10.008 SN - 1342-937X SN - 1878-0571 VL - 66 SP - 207 EP - 226 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Zellmeier, M. A1 - Brenner, Thomas J. K. A1 - Janietz, Silvia A1 - Nickel, N. H. A1 - Rappich, J. T1 - Polythiophenes as emitter layers for crystalline silicon solar cells BT - parasitic absorption, interface passivation, and open circuit voltage JF - Journal of applied physics N2 - We investigated the influence of the emitter (amorphous-Si, a-Si, or polythiophene derivatives: poly(3-hexylthiophene), P3HT, and poly(3-[3,6-dioxaheptyl]-thiophene), P3DOT) and the interface passivation (intrinsic a-Si or SiOX and methyl groups or SiOX) on the c-Si based 1 × 1 cm2 planar hybrid heterojunction solar cell parameters. We observed higher short circuit currents for the P3HT or P3DOT/c-Si solar cells than those obtained for a-Si/c-Si devices, independent of the interface passivation. The obtained VOC of 659 mV for the P3DOT/SiOX/c-Si heterojunction solar cell with hydrophilic 3,6-dioxaheptyl side chains is among the highest reported for c-Si/polythiophene devices. The maximum power conversion efficiency, PCE, was 11% for the P3DOT/SiOX/c-Si heterojunction solar cell. Additionally, our wafer lifetime measurements reveal a field effect passivation in the wafer induced by the polythiophenes when deposited on c-Si. Y1 - 2018 U6 - https://doi.org/10.1063/1.5006625 SN - 0021-8979 SN - 1089-7550 VL - 123 IS - 3 PB - American Institute of Physics CY - Melville ER - TY - JOUR A1 - Zemella, Anne A1 - Thoring, Lena A1 - Hoffmeister, Christian A1 - Samalikova, Maria A1 - Ehren, Patricia A1 - Wüstenhagen, Doreen Anja A1 - Kubick, Stefan T1 - Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin JF - Scientific reports N2 - As one of the most complex post-translational modification, glycosylation is widely involved in cell adhesion, cell proliferation and immune response. Nevertheless glycoproteins with an identical polypeptide backbone mostly differ in their glycosylation patterns. Due to this heterogeneity, the mapping of different glycosylation patterns to their associated function is nearly impossible. In the last years, glycoengineering tools including cell line engineering, chemoenzymatic remodeling and site-specific glycosylation have attracted increasing interest. The therapeutic hormone erythropoietin (EPO) has been investigated in particular by various groups to establish a production process resulting in a defined glycosylation pattern. However commercially available recombinant human EPO shows batch-to-batch variations in its glycoforms. Therefore we present an alternative method for the synthesis of active glycosylated EPO with an engineered O-glycosylation site by combining eukaryotic cell-free protein synthesis and site-directed incorporation of non-canonical amino acids with subsequent chemoselective modifications. Y1 - 2018 U6 - https://doi.org/10.1038/s41598-018-26936-x SN - 2045-2322 VL - 8 PB - Nature Publ. Group CY - London ER -