TY  - JOUR
A1  - Sand, Patrick
A1  - Schmidt, Bernd
T1  - Pd-catalyzed oxidative sulfoalkenylation of acetanilides and traceless removal of the catalyst directing group
JF  - ChemistrySelect
N2  - The palladium-catalyzed oxidative Heck-reaction, also referred to as Fujiwara-Moritani-reaction, has been investigated for the synthesis of styrenylsulfonyl compounds. Acetanilides and vinylsulfonyl compounds undergo dehydrogenative coupling reactions in moderate to quantitative yields, using benzoquinone as the oxidant of choice. Potassium peroxodisulfate, which had previously been identified as a superior oxidant for the coupling with acrylates, did not provide any coupling products with these olefins. Traceless removal of the catalyst directing group through a deacetylation-diazotation-coupling (DDC) sequence was demonstrated for 2-arylethene sulfones.
KW  - arenes
KW  - C− H activation
KW  - Heck reactions
KW  - Palladium
KW  - sulfones
Y1  - 2021
U6  - https://doi.org/10.1002/slct.202101009
SN  - 2365-6549
VL  - 6
IS  - 14
SP  - 3563
EP  - 3567
PB  - Wiley-VCH
CY  - Weinheim
ER  -