TY - JOUR A1 - Fitzi, Gregor A1 - Marcucci, Nicola T1 - Durkheim in Germany BT - the performance of a classic JF - Journal of Classical Sociology Y1 - 2017 U6 - https://doi.org/10.1177/1468795X17735991 SN - 1468-795X SN - 1741-2897 VL - 17 IS - 4 SP - 271 EP - 275 PB - Sage Publ. CY - London ER - TY - JOUR A1 - Fitzi, Gregor T1 - Dialogue. Divergence. Veiled Reception. Criticism: Georg Simmel’s relationship with Emile Durkheim JF - Journal of Classical Sociology N2 - Simmel was the only German sociologist who directly cooperated with Durkheim. After an initial impression of convergence between the sociology of social facts and the sociology of social forms, a break between the two founders of sociology became inevitable. Yet, Durkheim and Simmel went on positioning themselves against one other in the years ahead. Durkheim’s allegation of ‘individual psychologism’ induced Simmel to a veiled reception of Durkheim’s methodological approach that permitted him to refine the sociological epistemology he eventually presented in the Soziologie published in 1908. On this basis, he was able to formulate a final criticism of the sociology of social facts as a social psychology. KW - Sociology of social facts KW - sociology of social forms KW - moral sociology KW - transnormative sociology KW - criticism of social psychology Y1 - 2017 U6 - https://doi.org/10.1177/1468795X17735994 SN - 1468-795X SN - 1741-2897 VL - 17 SP - 293 EP - 308 PB - Sage Publ. CY - London ER - TY - GEN A1 - Fitzi, Gregor A1 - Joas, Hans A1 - Marcucci, Nicola T1 - Interview by Gregor Fitzi and Nicola Marcucci with Hans Joas on the reception of Emile Durkheim in Germany. Berlin: Humboldt University of Berlin, 6 October 2014 T2 - Journal of Classical Sociology N2 - The interview offers a reconstruction of the German reception of Durkheim since the middle of the 1970s. Hans Joas, who was one of its major protagonists, discusses the backdrop that finally permitted a scholarly examination of Durkheim’s sociology in Germany. Focussing on his personal reception Joas then gives an account of the Durkheimian themes that inspire his work. KW - Durkheim KW - human rights KW - modernity Y1 - 2017 U6 - https://doi.org/10.1177/1468795X17736131 SN - 1468-795X SN - 1741-2897 VL - 17 IS - 4 SP - 382 EP - 398 PB - Sage Publ. CY - London ER - TY - GEN A1 - Fitzi, Gregor A1 - Marcucci, Nicola A1 - Müller, Hans-Peter T1 - Interview by Gregor Fitzi and Nicola Marcucci with Hans-Peter Müller on the reception of Emile Durkheim in Germany. Berlin: Humboldt University of Berlin, 25 February 2015 T2 - Journal of Classical Sociology N2 - Just after the publication of the Theory of Communicative Action in 1981, a new generation of interpreters started a different reception of Durkheim in Germany. Hans-Peter Müller, sociologist and editor of the German translation of Leçons de sociologie, reconstructs the history of the German Durkheim’s Reception and illuminates the reasons for his interest in the French sociologist. He delivers different insights into the background which permitted the post-Habermasian generation to reach a new understanding of Durkheim’s work by enlightening the scientific and political conditions from which this new sensibility emerged. KW - Durkheim’s German Reception, Max Weber, Georg Simmel, Jürgen Habermas Y1 - 2017 U6 - https://doi.org/10.1177/1468795X17736132 SN - 1468-795X SN - 1741-2897 VL - 17 IS - 4 SP - 399 EP - 422 PB - Sage Publ. CY - London ER - TY - JOUR A1 - Groop, Per-Henrik A1 - Cooper, Mark E. A1 - Perkovic, Vlado A1 - Hocher, Berthold A1 - Kanasaki, Keizo A1 - Haneda, Masakazu A1 - Schernthaner, Guntram A1 - Sharma, Kumar A1 - Stanton, Robert C. A1 - Toto, Robert A1 - Cescutti, Jessica A1 - Gordat, Maud A1 - Meinicke, Thomas A1 - Koitka-Weber, Audrey A1 - Thiemann, Sandra A1 - von Eynatten, Maximilian T1 - Linagliptin and its effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction BT - the randomized MARLINA-T2D trial JF - Diabetes obesity & metabolism : a journal of pharmacology and therapeutics N2 - Aims: The MARLINA-T2D study (ClinicalTrials. gov, NCT01792518) was designed to investigate the glycaemic and renal effects of linagliptin added to standard-of-care in individuals with type 2 diabetes and albuminuria. Methods: A total of 360 individuals with type 2 diabetes, HbA1c 6.5% to 10.0% (48-86 mmol/ mol), estimated glomerular filtration rate (eGFR) >= 30 mL/min/1.73 m(2) and urinary albumin-tocreatinine ratio (UACR) 30-3000 mg/g despite single agent renin-angiotensin-system blockade were randomized to double-blind linagliptin (n = 182) or placebo (n = 178) for 24 weeks. The primary and key secondary endpoints were change from baseline in HbA1c at week 24 and time-weighted average of percentage change from baseline in UACR over 24 weeks, respectively. Results: Baseline mean HbA1c and geometric mean (gMean) UACR were 7.8% +/- 0.9% (62.2 +/- 9.6 mmol/mol) and 126 mg/g, respectively; 73.7% and 20.3% of participants had microalbuminuria or macroalbuminuria, respectively. After 24 weeks, the placebo-adjusted mean change in HbA1c from baseline was -0.60% (-6.6 mmol/mol) (95% confidence interval [CI], -0.78 to -0.43 [-8.5 to -4.7 mmol/mol]; P <.0001). The placebo-adjusted gMean for time-weighted average of percentage change in UACR from baseline was -6.0% (95% CI, -15.0 to 3.0; P =.1954). The adverse-event profile, including renal safety and change in eGFR, was similar between the linagliptin and placebo groups. Conclusions: In individuals at early stages of diabetic kidney disease, linagliptin significantly improved glycaemic control but did not significantly lower albuminuria. There was no significant change in placebo-adjusted eGFR. Detection of clinically relevant renal effects of linagliptin may require longer treatment, as its main experimental effects in animal studies have been to reduce interstitial fibrosis rather than alter glomerular haemodynamics. KW - antidiabetic drug KW - clinical trial KW - diabetic nephropathy KW - DPP-IV inhibitor KW - glycaemic control KW - linagliptin Y1 - 2017 U6 - https://doi.org/10.1111/dom.13041 SN - 1462-8902 SN - 1463-1326 VL - 19 IS - 11 SP - 1610 EP - 1619 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Morandi, Bertrand A1 - Kail, Jochem A1 - Tödter, Anne A1 - Wolter, Christian A1 - Piegay, Herve T1 - Diverse Approaches to Implement and Monitor River Restoration BT - a Comparative Perspective in France and Germany JF - Environmental Management N2 - River restoration is a main emphasis of river management in European countries. Cross-national comparisons of its implementation are still rare in scientific literature. Based on French and German national censuses, this study compares river restoration practices and monitoring by analysing 102 French and 270 German projects. This comparison aims to draw a spatial and temporal framework of restoration practices in both countries to identify potential drivers of cross-national similarities and differences. The results underline four major trends: (1) a lag of almost 15 years in river restoration implementation between France and Germany, with a consequently higher share of projects in Germany than in France, (2) substantial similarities in restored reach characteristics, short reach length, small rivers, and in "agricultural" areas, (3) good correspondences between stressors identified and restoration measures implemented. Morphological alterations were the most important highlighted stressors. River morphology enhancement, especially instream enhancements, were the most frequently implemented restoration measures. Some differences exist in specific restoration practices, as river continuity restoration were most frequently implemented in French projects, while large wood introduction or channel re-braiding were most frequently implemented in German projects, and (4) some quantitative and qualitative differences in monitoring practices and a significant lack of project monitoring, especially in Germany compared to France. These similarities and differences between Germany and France in restoration application and monitoring possibly result from a complex set of drivers that might be difficult to untangle (e.g., environmental, technical, political, cultural). KW - River restoration KW - Project monitoring KW - Hydromorphologic alteration KW - Mitigation measures KW - France KW - Germany Y1 - 2017 U6 - https://doi.org/10.1007/s00267-017-0923-3 SN - 0364-152X SN - 1432-1009 VL - 60 SP - 931 EP - 946 PB - Springer CY - New York ER - TY - JOUR A1 - Ferrer-Maestro, Juan José A1 - Kunst, Christiane A1 - Hernández de la Fuente, David A1 - Faber, Eike T1 - Prólogo JF - Entre los mundos: homenaje a Pedro Barceló = Zwischen den Welten : Festschrift für Pedro Barceló Y1 - 2017 SN - 978-2-84867-578-7 SP - 13 EP - 17 PB - Presses universitaires de Franche-Comté CY - Besançon ER - TY - JOUR A1 - Ferrer-Maestro, Juan José A1 - Kunst, Christiane A1 - Hernández de la Fuente, David A1 - Faber, Eike T1 - Vorwort JF - Entre los mundos: homenaje a Pedro Barceló = Zwischen den Welten : Festschrift für Pedro Barceló Y1 - 2017 SN - 978-2-84867-578-7 SP - 19 EP - 24 PB - Presses universitaires de Franche-Comté CY - Besançon ER - TY - JOUR A1 - Faber, Eike T1 - Augustus und die Provinzialen im Reichsdienst JF - Entre los mundos : homenaje a Pedro Barceló = Zwischen den Welten : Festschrift für Pedro Barceló Y1 - 2017 SN - 978-2-84867-578-7 SP - 101 EP - 119 PB - Presses universitaires de Franche-Comté CY - Besançon ER - TY - JOUR A1 - Brütt, Anna Levke A1 - Meister, Ramona A1 - Bernges, Tabea A1 - Moritz, Steffen A1 - Härter, Martin A1 - Kriston, Levente A1 - Kühne, Franziska T1 - Patient involvement in a systematic review BT - Development and pilot evaluation of a patient workshop JF - Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen N2 - Patient involvement (PI) in research is increasingly required as a means to improve relevance and meaningfulness of research results. PI has been widely promoted by the National Institute for Health Research in England in the last years. In Germany, widespread involvement of patients in research is still missing. The methods used to realize PI have been developed mainly in English research contexts, and detailed information on how to involve patients in systematic reviews is rare. Therefore, the aim of the study was that patients contribute and prioritize clinically relevant outcomes to a systematic review on meta-cognitive interventions, and to evaluate a patient workshop as well as patients’ perceptions of research involvement. Seven patients with experience in psychiatric care participated in our workshop. They focused on outcomes pre-defined in the review protocol (e.g., meta-cognitive or cognitive changes, symptomatology, quality of life), neglected other outcomes (like satisfaction with treatment, acceptability), and added relevant new ones (e.g., scope of action/autonomy, applicability). Altogether, they valued the explicit workshop participation positively. However, some suggested to involve patients at an earlier stage and to adapt the amount of information given. Further systematic reviews would benefit from the involvement of patients in the definition of other components of the review question (like patients or interventions), in the interpretation of key findings or in drafting a lay summary. N2 - Die Beteiligung von Patientinnen und Patienten in der Forschung wird zunehmend gefordert, um die Relevanz und Aussagefähigkeit von Forschungsergebnissen zu verbessern. Während das National Institute for Health Research in England die Patientenbeteiligung seit Jahren fördert, fehlt es in Deutschland noch weitgehend an flächendeckender Forschungsbeteiligung. Zudem liegen Informationen über Methoden der Patientenbeteiligung hauptsächlich für englische Forschungskontexte vor, und detaillierte Informationen zur Patientenbeteiligung in systematischen Reviews sind lückenhaft. Das Ziel der Studie war es daher, dass Patienten klinisch relevante Zielgrößen zu einem systematischen Review zu metakognitiven Interventionen beitragen und priorisieren und dass sie einen Patientenworkshop und ihre wahrgenommene Forschungsbeteiligung bewerten. Sieben psychiatrieerfahrene Patienten nahmen an unserem Workshop teil. Sie benannten Zielgrößen, die im Reviewprotokoll schon vorgesehen waren (z.B. metakognitive und kognitive Veränderungen, Symptomatik, Lebensqualität), vernachlässigten andere Endpunkte (z.B. Zufriedenheit, Akzeptanz) und fügten neue Zielgrößen hinzu (z.B. Handlungsspielräume/Autonomie, Anwendbarkeit). Die Patienten würdigten die Workshopteilnahme insgesamt. Einige empfahlen jedoch eine frühere Beteiligung und eine Anpassung der gegebenen Informationen. Zukünftige systematische Reviews können von der Beteiligung von Patienten bei der Definition weiterer Bestandteile der Fragestellung (wie Population oder Interventionen), der Interpretation zentraler Ergebnisse oder der Formulierung einer allgemeinverständlichen Zusammenfassung profitieren. T2 - Beteiligung von Patienten an einem systematischen Review: Entwicklung und Pilotevaluation eines Patientenworkshops KW - patient involvement KW - patient participation KW - consumer participation KW - systematic review KW - meta-analysis Y1 - 2017 U6 - https://doi.org/10.1016/j.zefq.2017.07.005 SN - 1865-9217 SN - 2212-0289 VL - 127-128 SP - 56 EP - 61 PB - Elsevier CY - Jena ER - TY - JOUR A1 - Miklashevsky, Alex A. T1 - О высоком и низком: пространственная семантика абстрактных и конкретных существительных JF - Tomsk state university journal N2 - Aim and material: In the present study, the data of the rating study presented earlier, where participants estimated the position of an object or phenomenon in vertical space by using the seven-point Likert scale, are used in order to systematically describe spatial information included in language units of different semantic categories. Background: The role of spatial semantics in language understanding is assumed by modern cognition theories and confirmed in experimental studies. Hypotheses: Based on conceptual metaphor theory, a number of hypotheses are proposed in the present study: different semantic categories of nouns (e.g., tools vs. animals vs. emotions etc.) should significantly differ in their spatial semantics as well; different semantic categories of abstract nouns (e.g., mental states vs. emotions vs. physical sensations) should also differ in their spatial semantics, as the latter is included in their conceptual structure; mental states and phenomena (e.g., imagination, thought or memory) should have higher values (i.e., be located higher in the virtual subjective space) than any other abstract concepts; emotional concepts (e.g., love, disgust or happiness) should be located higher than physical sensations (e.g., pain or softness); positive emotions (like joy or euphoria) should be located higher than negative ones (like feeling of guilt or disappointment). Methods: Statistical methods (parametric and non-parametric ones) are used in order to test the hypotheses. As additional cross-testing methods corpora data and expert assessment are included. Results: The results of the study confirmed all the hypotheses. A number of additional regularities were revealed: in general, abstract concepts get higher values on a scale, i.e., are located higher in the virtual subjective space than concrete ones; tool concepts are related more to the lower space, unlike sound concepts that are related to higher space. No difference was found between action concepts (like attack or running) and physical sensations. Discussion: The results obtained can also be explained in terms of other theories within the embodied cognition framework, as it is discussed in the conclusion (words as social tools by A. Borghi and F. Binkofski; ideas by G. Vigliocco and neurosemantic approach by F. Pulvermuller). The need in an integrative model and larger studies with other semantic categories is underlined. N2 - Проведен анализ пространственной семантики различных категорий русских существительных, входящих в психолингви-стическую базуданных; особое внимание уделяется абстрактным концептам. Выявлены различия пространственной семантики наименований физических ощущений и действий, эмоций, ментальных процессов. Полученны ерезультаты обсуждаются с точки зрения отдельных подходов в рамках теории воплощенного познания – теории концептуальной метафоры, теории слов как социальных инструментов (WAT, Words As social Tools), нейросемантики. T2 - About the high and the low: spatial semantics of abstract and concrete nouns KW - embodied cognition KW - spatial semantics KW - conceptual metaphor KW - neurosemantics KW - words as social tools KW - psycholinguistic databases KW - abstract concepts KW - абстрактные концепты KW - психолингвистическая база данных KW - слова как социальные инструменты KW - нейросемантика KW - концептуальная метафора KW - пространственная семантика KW - воплощенное познание Y1 - 2017 U6 - https://doi.org/10.17223/15617793/424/4 SN - 1561-7793 SN - 1561-803X IS - 424 SP - 26 EP - 34 PB - Tomsk Stata Univ CY - Tomsk ER - TY - JOUR A1 - Berry, Scott A1 - Rosa, Stefanie A1 - Howard, Martin A1 - Buhler, Marc A1 - Dean, Caroline T1 - Disruption of an RNA-binding hinge region abolishes LHP1-mediated epigenetic repression JF - Genes & Development N2 - Epigenetic maintenance of gene repression is essential for development. Polycomb complexes are central to this memory, but many aspects of the underlying mechanism remain unclear. LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) binds Polycomb-deposited H3K27me3 and is required for repression of many Polycomb target genes in Arabidopsis. Here we show that LHP1 binds RNA in vitro through the intrinsically disordered hinge region. By independently perturbing the RNA-binding hinge region and H3K27me3 (trimethylation of histone H3 at Lys27) recognition, we found that both facilitate LHP1 localization and H3K27me3 maintenance. Disruption of the RNAbinding hinge region also prevented formation of subnuclear foci, structures potentially important for epigenetic repression. KW - chromatin KW - epigenetics KW - plant biology KW - Polycomb KW - RNA Y1 - 2017 U6 - https://doi.org/10.1101/gad.305227.117 SN - 0890-9369 SN - 1549-5477 VL - 31 SP - 2115 EP - 2120 PB - Cold Spring Harbor Laboratory Press CY - Cold Spring Harbor, NY ER - TY - JOUR A1 - Dimitrova, Ilinka A1 - Koppitz, Jörg T1 - On the semigroup of all partial fence-preserving injections on a finite set JF - Journal of Algebra and Its Applications N2 - For n∈N , let Xn={a1,a2,…,an} be an n-element set and let F=(Xn;