TY  - JOUR
A1  - Eichler, Sarah
A1  - Salzwedel, Annett
A1  - Reibis, Rona
A1  - Nothroff, Jörg
A1  - Harnath, Axel
A1  - Schikora, Martin
A1  - Butter, Christian
A1  - Wegscheider, Karl
A1  - Völler, Heinz
T1  - Multicomponent cardiac rehabilitation in patients after transcatheter aortic valve implantation
BT  - predictors of functional and psychocognitive recovery
JF  - European journal of preventive cardiology : the official ESC journal for primary & secondary cardiovascular prevention, rehabilitation and sports cardiology
N2  - Background: In the last decade, transcatheter aortic valve implantation has become a promising treatment modality for patients with aortic stenosis and a high surgical risk. Little is known about influencing factors of function and quality of life during multicomponent cardiac rehabilitation. Methods: From October 2013 to July 2015, patients with elective transcatheter aortic valve implantation and a subsequent inpatient cardiac rehabilitation were enrolled in the prospective cohort multicentre study. Frailty-Index (including cognition, nutrition, autonomy and mobility), Short Form-12 (SF-12), six-minute walk distance (6MWD) and maximum work load in bicycle ergometry were performed at admission and discharge of cardiac rehabilitation. The relation between patient characteristics and improvements in 6MWD, maximum work load or SF-12 scales were studied univariately and multivariately using regression models. Results: One hundred and thirty-six patients (80.6 +/- 5.0 years, 47.8% male) were enrolled. 6MWD and maximum work load increased by 56.3 +/- 65.3 m (p < 0.001) and 8.0 +/- 14.9 watts (p < 0.001), respectively. An improvement in SF-12 (physical 2.5 +/- 8.7, p = 0.001, mental 3.4 +/- 10.2, p = 0.003) could be observed. In multivariate analysis, age and higher education were significantly associated with a reduced 6MWD, whereas cognition and obesity showed a positive predictive value. Higher cognition, nutrition and autonomy positively influenced the physical scale of SF-12. Additionally, the baseline values of SF-12 had an inverse impact on the change during cardiac rehabilitation. Conclusions: Cardiac rehabilitation can improve functional capacity as well as quality of life and reduce frailty in patients after transcatheter aortic valve implantation. An individually tailored therapy with special consideration of cognition and nutrition is needed to maintain autonomy and empower octogenarians in coping with challenges of everyday life.
KW  - Cardiac rehabilitation
KW  - TAVI
KW  - frailty
KW  - quality of life
KW  - exercise capacity
Y1  - 2017
U6  - https://doi.org/10.1177/2047487316679527
SN  - 2047-4873
SN  - 2047-4881
VL  - 24
IS  - 3
SP  - 257
EP  - 264
PB  - Sage Publ.
CY  - London
ER  -