TY  - JOUR
A1  - Juerchott, Kathrin
A1  - Guo, Ke-Tai
A1  - Catchpole, Gareth
A1  - Feher, Kristen
A1  - Willmitzer, Lothar
A1  - Schichor, Christian
A1  - Selbig, Joachim
T1  - Comparison of metabolite profiles in U87 glioma cells and mesenchymal stem cells
JF  - Biosystems : journal of biological and information processing sciences
N2  - Gas chromatography-mass spectrometry (GC-MS) profiles were generated from U87 glioma cells and human mesenchymal stem cells (hMSC). 37 metabolites representing glycolysis intermediates, TCA cycle metabolites, amino acids and lipids were selected for a detailed analysis. The concentrations of these. metabolites were compared and Pearson correlation coefficients were used to calculate the relationship between pairs of metabolites. Metabolite profiles and correlation patterns differ significantly between the two cell lines. These profiles can be considered as a signature of the underlying biochemical system and provide snap-shots of the metabolism in mesenchymal stem cells and tumor cells.
KW  - Metabolite profiles
KW  - Correlation networks
KW  - U87 glioma cells
KW  - Human mesenchymal stem cells
Y1  - 2011
U6  - https://doi.org/10.1016/j.biosystems.2011.05.005
SN  - 0303-2647
VL  - 105
IS  - 2
SP  - 130
EP  - 139
PB  - Elsevier
CY  - Oxford
ER  -