TY - JOUR A1 - Schmitz, Andreas A1 - Schmidt-Wellenburg, Christian A1 - Witte, Daniel A1 - Keil, Maria T1 - In welcher Gesellschaft forschen wir eigentlich? BT - Struktur und Dynamik des Feldes der deutschen Soziologie JF - Zeitschrift für theoretische Soziologie Y1 - 2020 U6 - https://doi.org/10.3262/ZTS1902245 SN - 2195-0695 SN - 2751-4552 VL - 8 IS - 2 SP - 245 EP - 281 PB - Beltz Juventa CY - Weinheim ER - TY - JOUR A1 - Stage, Diana A1 - Hellmann, Uwe T1 - Strafbarkeit eines Arztes bei einem freiverantwortlichen Suizid des Patienten JF - Juris-PraxisReport. Strafrecht N2 - Angesichts der gewachsenen Bedeutung der Selbstbestimmung des Einzelnen auch bei Entscheidungen über sein Leben kann in Fällen des freiverantwortlichen Suizids der Arzt, der die Umstände kennt, nicht mit strafrechtlichen Konsequenzen verpflichtet werden, gegen den Willen des Suizidenten zu handeln. Y1 - 2020 UR - https://www.juris.de/r3/document/jpr-NLSF000001620 SN - 1865-8334 IS - 04 PB - Juris GmbH CY - Saarbrücken ER - TY - JOUR A1 - Schmidt, Max Oliver T1 - Kirchenasyl als Solidarisierung BT - umkämpftes soziales Gut JF - Pax Zeit : Zeitschrift der Deutschen Sektion von Pax Christi Y1 - 2020 UR - https://www.paxchristi.de/file/download/AMIfv952MjWMWXF-eVYzdtrIjuo8hyDLrWsf5NBFQUsAQw3zfj810BcAFgK2by2QzIVlFyqpsGHeZgNuUZCcIWE38BZNJZcARf3aHRxCzVwJHx8fpKChqCsuTh85-vPie_7LkDR8bJ0Fj9esgQYS7uwlyuja-WmR4sBlc5d478j-3PVLAybx17jAuROPcPta3t1E4OSHeV6YpNlWYSNhTZaUJdIDeqZrXCEPNVDDtq9Kt55SUxPceAkUx9u2zwYvM9NUwqd1tWp0wtu-rzv2nm6TpR55u9wghouR583U4pTPoB3M9k_ayBM/pax_zeit%201_2020.pdf IS - 1 SP - 16 EP - 17 PB - Pax Christi-Bewegung, Dt. Sektion CY - Berlin ER - TY - JOUR A1 - Esfahani, Reza Dokht Dolatabadi A1 - Gholami, Ali A1 - Ohrnberger, Matthias T1 - An inexact augmented Lagrangian method for nonlinear dispersion-curve inversion using Dix-type global linear approximation JF - Geophysics : a journal of general and applied geophysics N2 - Dispersion-curve inversion of Rayleigh waves to infer subsurface shear-wave velocity is a long-standing problem in seismology. Due to nonlinearity and ill-posedness, sophisticated regularization techniques are required to solve the problem for a stable velocity model. We have formulated the problem as a minimization problem with nonlinear operator constraint and then solve it by using an inexact augmented Lagrangian method, taking advantage of the Haney-Tsai Dix-type relation (a global linear approximation of the nonlinear forward operator). This replaces the original regularized nonlinear problem with iterative minimization of a more tractable regularized linear problem followed by a nonlinear update of the phase velocity (data) in which the update can be performed accurately with any forward modeling engine, for example, the finite-element method. The algorithm allows discretizing the medium with thin layers (for the finite-element method) and thus omitting the layer thicknesses from the unknowns and also allows incorporating arbitrary regularizations to shape the desired velocity model. In this research, we use total variation regularization to retrieve the shear-wave velocity model. We use two synthetic and two real data examples to illustrate the performance of the inversion algorithm with total variation regularization. We find that the method is fast and stable, and it converges to the solution of the original nonlinear problem. KW - surface wave KW - nonlinear KW - inversion KW - modeling KW - finite element Y1 - 2020 U6 - https://doi.org/10.1190/geo2019-0717.1 SN - 0016-8033 SN - 1942-2156 VL - 85 IS - 3 SP - EN77 EP - EN85 PB - GeoScienceWorld CY - Tulsa, Okla. ER - TY - JOUR A1 - Ohlert, Clemens A1 - Boos, Pauline T1 - Auswirkungen der Digitalisierung auf Geschlechterungleichheiten T1 - Digital transformation and gender inequality BT - eine empirische Untersuchung auf Branchenebene BT - an empirical analysis at the sector level JF - Arbeit N2 - Ausgehend von der Debatte um die Genderaspekte der Digitalisierung der Arbeit untersuchen wir den Zusammenhang zwischen der Nutzung digitaler Technologien und der Entwicklung von Geschlechterungleichheiten empirisch. Die Ergebnisse zeigen, dass Frauen in Branchen mit hohem Digitalisierungsgrad unterrepräsentiert sind und dass sich diese Dimension der Geschlechtersegregation in den letzten Jahren verstärkte. Die Unterrepräsentation von Frauen in Branchen mit hohem Digitalisierungsgrad geht mit Nachteilen bei den Verdiensten einher. Die Ergebnisse zeigen zudem, dass der Gender Pay Gap in Branchen mit hohem Digitalisierungsgrad tendenziell größer ist und über die Zeit weniger zurückging als in Branchen, in denen weniger digitale Technologien genutzt werden. N2 - Departing from previously discussed gender aspects of digitalization, we empirically investigate the relation between the use of digital technologies and the evolution of gender inequalities. The results show that women are underrepresented in sectors which apply more digital technologies and that this segregation has increased in the past years. The underrepresentation of women in sectors with a higher degree of digital technology usage goes along with lower wages. The results further show that the Gender Pay Gap is larger and more persistent in sectors with a higher degree of digital technology usage than in sectors with less intense technology application. KW - Digitalisierung KW - Geschlechtersegregation KW - Gender Pay Gap KW - digital transformation KW - gender segregation KW - gender pay gap Y1 - 2020 U6 - https://doi.org/10.1515/arbeit-2020-0015 SN - 0941-5025 SN - 2365-984X VL - 29 IS - 3-4 SP - 195 EP - 218 PB - De Gruyter Oldenbourg CY - Berlin ER - TY - JOUR A1 - Reith, Florian A1 - Seyfried, Markus T1 - Qualitätsmanagement und das Puffern externer und interner Anforderungen JF - Qualität in der Wissenschaft N2 - The following article deals with the new-institutionalist concept of buffering. The concept describes in short, how organizations cope with external and internal demands in order to gain or maintain legitimacy. The article applies this approach to quality management in higher education. We argue, that the introduction of quality management is a reaction to external demands to achieve more quality in teaching and learning. Simultaneously, it functions as a buffer for other organizational subunits within the higher education institution and tries to prevent them from becoming overloaded with external demands. Based on interviews from a research project, the article shows, that both quality managers and higher education managers partly perceive quality management as service unit, which prevents the departments from exaggerating external demands. Y1 - 2020 UR - https://www.universitaetsverlagwebler.de/_files/ugd/7bac3c_cf5f33dc80604269b9d71dccde06d8bf.pdf SN - 1860-3041 VL - 14 IS - 2 SP - 44 EP - 49 PB - UVW Univ.-Verl. Webler CY - Bielefeld ER - TY - JOUR A1 - Ansmann, Moritz A1 - Seyfried, Markus T1 - Zwischen Anspruch und Realität BT - evidenzbasierte Qualitätsentwicklung durch Integration von Qualitätsmanagement und Hochschuldidaktik JF - HDS.Journal N2 - Eine evidenzbasierte Gestaltung von Studium und Lehre, wie sie heute normativ eingefordert wird, bedarf des integrierten Zusammenwirkens von Qualitätsmanagement und Hochschuldidaktik – aber gibt es dieses in der Praxis? Mit Blick auf die allgemeine Befundlage, aber auch anhand einer eigenen empirischen Untersuchung zeigt der Beitrag diesbezüglich auf, dass Qualitätsmanagement und Hochschuldidaktik als weitgehend desintegrierte Funktionsbereiche wahrgenommen werden und Evidenzbasierung in der Praxis folglich keinen sehr hohen Stellenwert genießt. Ausgehend von einer Ursachenanalyse wird auf die dysfunktionalen, aber auch auf die funktionalen Auswirkungen dieser Separierung aufmerksam gemacht. KW - Qualitätsmanagement KW - Qualitätssicherung KW - Evidenzbasierung KW - Organisationsforschung KW - Zusammenarbeit KW - quality management KW - quality assurance KW - evidence-based research KW - organizational research KW - collaboration Y1 - 2020 UR - https://nbn-resolving.org/urn:nbn:de:bsz:15-qucosa2-725827 SN - 2195-0334 VL - 2020 IS - 1 SP - 6 EP - 11 PB - Hochschuldidaktisches Zentrum Sachsen (HDS) CY - Leipzig ER - TY - JOUR A1 - Franzke, Jochen T1 - Deutschlands Krisenmanagement in der CORONA-Pandemie. BT - Herausforderungen eines föderalen politisch-administrativen Systems JF - Rocznik Integracji Europejskiej JF - Yearbook of European integration KW - CORONA-Krise KW - Deutschland KW - Föderalismus KW - Krisenmanagement KW - Öffentliche Verwaltung Y1 - 2020 U6 - https://doi.org/10.14746/rie.2020.14.21 SN - 1899-6256 VL - 14 SP - 325 EP - 342 PB - Uniwersytet im. Adama Mickiewicza w Poznaniu CY - Poznań ER - TY - JOUR A1 - Raoufi, Meysam A1 - Hörmann, Ulrich A1 - Ligorio, Giovanni A1 - Hildebrandt, Jana A1 - Pätzel, Michael A1 - Schultz, Thorsten A1 - Perdigon-Toro, Lorena A1 - Koch, Norbert A1 - List-Kratochvil, Emil A1 - Hecht, Stefan A1 - Neher, Dieter T1 - Simultaneous effect of ultraviolet radiation and surface modification on the work function and hole injection properties of ZnO thin films JF - Physica Status Solidi. A , Applications and materials science N2 - The combined effect of ultraviolet (UV) light soaking and self-assembled monolayer deposition on the work function (WF) of thin ZnO layers and on the efficiency of hole injection into the prototypical conjugated polymer poly(3-hexylthiophen-2,5-diyl) (P3HT) is systematically investigated. It is shown that the WF and injection efficiency depend strongly on the history of UV light exposure. Proper treatment of the ZnO layer enables ohmic hole injection into P3HT, demonstrating ZnO as a potential anode material for organic optoelectronic devices. The results also suggest that valid conclusions on the energy-level alignment at the ZnO/organic interfaces may only be drawn if the illumination history is precisely known and controlled. This is inherently problematic when comparing electronic data from ultraviolet photoelectron spectroscopy (UPS) measurements carried out under different or ill-defined illumination conditions. KW - charge injection across hybrid interfaces KW - energy-level alignments KW - hybrid metal oxides KW - organic interfaces Y1 - 2020 U6 - https://doi.org/10.1002/pssa.201900876 SN - 1862-6300 SN - 1862-6319 VL - 217 IS - 5 SP - 1 EP - 6 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Jarecki, Jana B. A1 - Tan, Jolene H. A1 - Jenny, Mirjam T1 - A framework for building cognitive process models JF - Psychonomic bulletin & review : a journal of the Psychonomic Society N2 - The termprocess modelis widely used, but rarely agreed upon. This paper proposes a framework for characterizing and building cognitive process models. Process models model not only inputs and outputs but also model the ongoing information transformations at a given level of abstraction. We argue that the following dimensions characterize process models: They have a scope that includes different levels of abstraction. They specify a hypothesized mental information transformation. They make predictions not only for the behavior of interest but also for processes. The models' predictions for the processes can be derived from the input, without reverse inference from the output data. Moreover, the presumed information transformation steps are not contradicting current knowledge of human cognitive capacities. Lastly, process models require a conceptual scope specifying levels of abstraction for the information entering the mind, the proposed mental events, and the behavior of interest. This framework can be used for refining models before testing them or after testing them empirically, and it does not rely on specific modeling paradigms. It can be a guideline for developing cognitive process models. Moreover, the framework can advance currently unresolved debates about which models belong to the category of process models. KW - cognitive process model KW - cognitive model KW - computational model KW - definitions KW - Marr's levels Y1 - 2020 U6 - https://doi.org/10.3758/s13423-020-01747-2 SN - 1069-9384 SN - 1531-5320 VL - 27 IS - 6 SP - 1218 EP - 1229 PB - Springer CY - New York, NY ER - TY - JOUR A1 - Ben Dor, Yoav A1 - Neugebauer, Ina A1 - Enzel, Yehouda A1 - Schwab, Markus J. A1 - Tjallingii, Rik A1 - Erel, Yigal A1 - Brauer, Achim T1 - Reply to comment on: Ben Dor, Yoav et al. : Varves of the Dead Sea sedimentary record. - In: Quaternary science reviews : the international multidisciplinary research and review journal. - 215 (2019), S. 173 - 184. - (ISSN: 0277-3791). - https://doi.org/10.1016/j.quascirev.2019.04.011 JF - Quaternary science reviews : the international multidisciplinary research and review journal N2 - In the comment on "Varves of the Dead Sea sedimentary record." Quaternary Science Reviews 215 (Ben Dor et al., 2019): 173-184. by R. Bookman, two recently published papers are suggested to prove that the interpretation of the laminated sedimentary sequence of the Dead Sea, deposited mostly during MIS2 and Holocene pluvials, as annual deposits (i.e., varves) is wrong. In the following response, we delineate several lines of evidence which coalesce to demonstrate that based on the vast majority of evidence, including some of the evidence provided in the comment itself, the interpretation of these sediments as varves is the more likely scientific conclusion. We further discuss the evidence brought up in the comment and its irrelevance and lack of robustness for addressing the question under discussion. Y1 - 2020 U6 - https://doi.org/10.1016/j.quascirev.2019.106063 SN - 0277-3791 VL - 231 PB - Elsevier CY - Amsterdam [u.a.] ER - TY - JOUR A1 - Terao, Mineko A1 - Garattini, Enrico A1 - Romão, Maria João A1 - Leimkühler, Silke T1 - Evolution, expression, and substrate specificities of aldehyde oxidase enzymes in eukaryotes JF - The journal of biological chemistry N2 - Aldehyde oxidases (AOXs) are a small group of enzymes belonging to the larger family of molybdo-flavoenzymes, along with the well-characterized xanthine oxidoreductase. The two major types of reactions that are catalyzed by AOXs are the hydroxylation of heterocycles and the oxidation of aldehydes to their corresponding carboxylic acids. Different animal species have different complements of AOX genes. The two extremes are represented in humans and rodents; whereas the human genome contains a single active gene (AOX1), those of rodents, such as mice, are endowed with four genes (Aox1-4), clustering on the same chromosome, each encoding a functionally distinct AOX enzyme. It still remains enigmatic why some species have numerous AOX enzymes, whereas others harbor only one functional enzyme. At present, little is known about the physiological relevance of AOX enzymes in humans and their additional forms in other mammals. These enzymes are expressed in the liver and play an important role in the metabolisms of drugs and other xenobiotics. In this review, we discuss the expression, tissue-specific roles, and substrate specificities of the different mammalian AOX enzymes and highlight insights into their physiological roles. KW - metalloenzyme KW - molybdenum KW - mouse KW - drug metabolism KW - flavoprotein KW - xenobiotic KW - oxidase KW - oxygen radicals KW - iron-sulfur protein KW - aldehyde oxidase (AOX) KW - enzyme evolution KW - metal-containing enzyme KW - molybdenum cofactor (Moco) KW - molybdo-flavoenzyme KW - 2Fe-2S cluster KW - flavin adenine dinucleotide (FAD) Y1 - 2020 U6 - https://doi.org/10.1074/jbc.REV119.007741 SN - 0021-9258 SN - 1083-351X VL - 295 IS - 16 SP - 5377 EP - 5389 PB - American Society for Biochemistry and Molecular Biology CY - Rockville ER - TY - JOUR A1 - Kunstmann, Ruth Sonja A1 - Engström, Olof A1 - Wehle, Marko A1 - Widmalm, Göran A1 - Santer, Mark A1 - Barbirz, Stefanie T1 - Increasing the affinity of an O-Antigen polysaccharide binding site in Shigella flexneri bacteriophage Sf6 tailspike protein JF - Chemistry – A European Journal N2 - Broad and unspecific use of antibiotics accelerates spread of resistances. Sensitive and robust pathogen detection is thus important for a more targeted application. Bacteriophages contain a large repertoire of pathogen-binding proteins. These tailspike proteins (TSP) often bind surface glycans and represent a promising design platform for specific pathogen sensors. We analysed bacteriophage Sf6 TSP that recognizes the O-polysaccharide of dysentery-causing Shigella flexneri to develop variants with increased sensitivity for sensor applications. Ligand polyrhamnose backbone conformations were obtained from 2D H-1,H-1-trNOESY NMR utilizing methine-methine and methine-methyl correlations. They agreed well with conformations obtained from molecular dynamics (MD), validating the method for further predictions. In a set of mutants, MD predicted ligand flexibilities that were in good correlation with binding strength as confirmed on immobilized S. flexneri O-polysaccharide (PS) with surface plasmon resonance. In silico approaches combined with rapid screening on PS surfaces hence provide valuable strategies for TSP-based pathogen sensor design. KW - carbohydrates KW - molecular dynamics simulations KW - NMR spectroscopy KW - protein-carbohydrate interactions KW - surface plasmon resonance Y1 - 2020 U6 - https://doi.org/10.1002/chem.202000495 SN - 0947-6539 SN - 1521-3765 VL - 26 IS - 32 SP - 7263 EP - 7273 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Köster, Antonia A1 - Matt, Christian A1 - Hess, Thomas T1 - Do all roads lead to Rome? BT - exploring the relationship between social referrals, referral propensity and stickiness to video-on-demand websites JF - Business and Information Systems Engineering N2 - Content website providers have two main goals: They seek to attract consumers and to keep them on their websites as long as possible. To reach potential consumers, they can utilize several online channels, such as paid search results or advertisements on social media, all of which usually require a substantial marketing budget. However, with rising user numbers of online communication tools, website providers increasingly integrate social sharing buttons on their websites to encourage existing consumers to facilitate referrals to their social networks. While little is known about this social form of guiding consumers to a content website, the study proposes that the way in which consumers reach a website is related to their stickiness to the website and their propensity to refer content to others. By using a unique clickstream data set of a video-on-demand website, the study compares consumers referred by their social network to those consumers arriving at the website via organic search or social media advertisements in terms of stickiness to the website (e.g., visit length, number of page views, video starts) and referral likelihood. The results show that consumers referred through social referrals spend more time on the website, view more pages, and start more videos than consumers who respond to social media advertisements, but less than those coming through organic search. Concerning referral propensity, the results indicate that consumers attracted to a website through social referrals are more likely to refer content to others than those who came through organic search or social media advertisements. The study offers direct insights to managers and recommends an increase in their efforts to promote social referrals on their websites. KW - social referrals KW - organic search KW - social media advertising KW - website stickiness KW - referral propensity Y1 - 2020 U6 - https://doi.org/10.1007/s12599-020-00660-1 SN - 1867-0202 VL - 63 SP - 349 EP - 366 PB - Springer CY - Wiesbaden ER - TY - JOUR A1 - Griscom, Bronson W. A1 - Busch, Jonah A1 - Cook-Patton, Susan C. A1 - Ellis, Peter W. A1 - Funk, Jason A1 - Leavitt, Sara M. A1 - Lomax, Guy A1 - Turner, Will R. A1 - Chapman, Melissa A1 - Streck, Charlotte T1 - National mitigation potential from natural climate solutions in the tropics JF - Biological sciences N2 - Better land stewardship is needed to achieve the Paris Agreement's temperature goal, particularly in the tropics, where greenhouse gas emissions from the destruction of ecosystems are largest, and where the potential for additional land carbon storage is greatest. As countries enhance their nationally determined contributions (NDCs) to the Paris Agreement, confusion persists about the potential contribution of better land stewardship to meeting the Agreement's goal to hold global warming below 2 degrees C. We assess cost-effective tropical country-level potential of natural climate solutions (NCS)-protection, improved management and restoration of ecosystems-to deliver climate mitigation linked with sustainable development goals (SDGs). We identify groups of countries with distinctive NCS portfolios, and we explore factors (governance, financial capacity) influencing the feasibility of unlocking national NCS potential. Cost-effective tropical NCS offers globally significant climate mitigation in the coming decades (6.56 Pg CO(2)e yr(-1) at less than 100 US$ per Mg CO(2)e). In half of the tropical countries, cost-effective NCS could mitigate over half of national emissions. In more than a quarter of tropical countries, cost-effective NCS potential is greater than national emissions. We identify countries where, with international financing and political will, NCS can cost-effectively deliver the majority of enhanced NDCs while transforming national economies and contributing to SDGs. This article is part of the theme issue 'Climate change and ecosystems: threats, opportunities and solutions'. KW - natural climate solutions KW - climate mitigation KW - protection KW - land management KW - restoration KW - Paris Agreement Y1 - 2020 U6 - https://doi.org/10.1098/rstb.2019.0126 SN - 0962-8436 SN - 1471-2970 VL - 375 IS - 1794 SP - 1 EP - 11 PB - The Royal Society Publishing CY - London ER - TY - JOUR A1 - Thirumalaikumar, Venkatesh P. A1 - Gorka, Michal A1 - Schulz, Karina A1 - Masclaux-Daubresse, Celine A1 - Sampathkumar, Arun A1 - Skirycz, Aleksandra A1 - Vierstra, Richard D. A1 - Balazadeh, Salma T1 - Selective autophagy regulates heat stress memory in Arabidopsis by NBR1-mediated targeting of HSP90.1 and ROF1 JF - Autophagy N2 - In nature, plants are constantly exposed to many transient, but recurring, stresses. Thus, to complete their life cycles, plants require a dynamic balance between capacities to recover following cessation of stress and maintenance of stress memory. Recently, we uncovered a new functional role for macroautophagy/autophagy in regulating recovery from heat stress (HS) and resetting cellular memory of HS inArabidopsis thaliana. Here, we demonstrated that NBR1 (next to BRCA1 gene 1) plays a crucial role as a receptor for selective autophagy during recovery from HS. Immunoblot analysis and confocal microscopy revealed that levels of the NBR1 protein, NBR1-labeled puncta, and NBR1 activity are all higher during the HS recovery phase than before. Co-immunoprecipitation analysis of proteins interacting with NBR1 and comparative proteomic analysis of annbr1-null mutant and wild-type plants identified 58 proteins as potential novel targets of NBR1. Cellular, biochemical and functional genetic studies confirmed that NBR1 interacts with HSP90.1 (heat shock protein 90.1) and ROF1 (rotamase FKBP 1), a member of the FKBP family, and mediates their degradation by autophagy, which represses the response to HS by attenuating the expression ofHSPgenes regulated by the HSFA2 transcription factor. Accordingly, loss-of-function mutation ofNBR1resulted in a stronger HS memory phenotype. Together, our results provide new insights into the mechanistic principles by which autophagy regulates plant response to recurrent HS. KW - Arabidopsis thaliana KW - heat stress KW - HSFA2 KW - HSP90.1 KW - NBR1 KW - ROF1 KW - selective autophagy KW - stress memory KW - stress recovery Y1 - 2020 U6 - https://doi.org/10.1080/15548627.2020.1820778 SN - 1554-8635 VL - 17 IS - 9 SP - 2184 EP - 2199 PB - Taylor & Francis CY - Abingdon ER - TY - JOUR A1 - von Steinau-Steinrück, Robert T1 - Kurzarbeitergeld JF - Berliner Anwaltsblatt N2 - Das Kurzarbeitergeld (nachfolgend: KuG) ist eines der wichtigsten Instrumente zur Überwindung der aktuellen Corona-Krise. Der Staat übernimmt einen Teil der Lohnkosten und hilft so, gleichzeitig Arbeitsplätze zu erhalten und die Unternehmen zu entlasten. Kurzarbeit ist die vorübergehende Kürzung der betriebsüblichen normalen Arbeitszeit wegen Mangels an Arbeit bei entsprechender Minderung der Entgeltansprüche. Das KuG ersetzt den Teil des Entgelts, der in Folge des Arbeitsausfalls nicht erarbeitet und ausgezahlt werden kann. Ohne KuG läge das Wirtschaftsrisiko beim Arbeitgeber. Könnte er seine Mitarbeiter wegen der Corona-Krise nicht beschäftigen, würde er nach § 615 Satz 1 BGB den vollen Annahmeverzugslohn schulden. Davon entlastet ihn das Instrument der Kurzarbeit. Das KuG deckt die sog. „Nettoentgeltdifferenz“ zwischen dem bisherigen „Soll-Entgelt“ und dem nach Reduzierung von Arbeitszeit verbleibenden „Ist- Entgelt“ in Höhe von 60 % bzw. bei Arbeitnehmern mit Kindern 67 % ab. Schon in der Finanzkrise 2008/2009 hat sich das KuG hervorragend bewährt, damit Unternehmen ihre Belegschaft behalten können, um nach Ende der Krise wieder voll „durchzustarten“. Y1 - 2020 UR - https://berlineranwaltsblatt.de/ce/kurzarbeitergeld/detail.html SN - 0930-3065 SN - 2510-5116 IS - 06 SP - 223 EP - 224 PB - Erich Schmidt Verlag CY - Berlin ER - TY - JOUR A1 - Gleich, Tobias A1 - Spitta, Gianna A1 - Butler, Oisin A1 - Zacharias, Kristin A1 - Aydin, Semiha A1 - Sebold, Miriam Hannah A1 - Garbusow, Maria A1 - Rapp, Michael A. A1 - Schubert, Florian A1 - Buchert, Ralph A1 - Heinz, Andreas A1 - Gallinat, Jürgen T1 - Dopamine D2/3 receptor availability in alcohol use disorder and individuals at high risk BT - towards a dimensional approach JF - Addiction Biology N2 - Alcohol use disorder (AUD) is the most common substance use disorder worldwide. Although dopamine-related findings were often observed in AUD, associated neurobiological mechanisms are still poorly understood. Therefore, in the present study, we investigate D2/3 receptor availability in healthy participants, participants at high risk (HR) to develop addiction (not diagnosed with AUD), and AUD patients in a detoxified stage, applying F-18-fallypride positron emission tomography (F-18-PET). Specifically, D2/3 receptor availability was investigated in (1) 19 low-risk (LR) controls, (2) 19 HR participants, and (3) 20 AUD patients after alcohol detoxification. Quality and severity of addiction were assessed with clinical questionnaires and (neuro)psychological tests. PET data were corrected for age of participants and smoking status. In the dorsal striatum, we observed significant reductions of D2/3 receptor availability in AUD patients compared with LR participants. Further, receptor availability in HR participants was observed to be intermediate between LR and AUD groups (linearly decreasing). Still, in direct comparison, no group difference was observed between LR and HR groups or between HR and AUD groups. Further, the score of the Alcohol Dependence Scale (ADS) was inversely correlated with D2/3 receptor availability in the combined sample. Thus, in line with a dimensional approach, striatal D2/3 receptor availability showed a linear decrease from LR participants to HR participants to AUD patients, which was paralleled by clinical measures. Our study shows that a core neurobiological feature in AUD seems to be detectable in an early, subclinical state, allowing more individualized alcohol prevention programs in the future. KW - alcohol KW - D2/3 receptors KW - dependence KW - dopamine KW - high risk KW - PET Y1 - 2020 U6 - https://doi.org/10.1111/adb.12915 SN - 1369-1600 VL - 26 IS - 2 SP - 1 EP - 10 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Leins, Johannes A. A1 - Banitz, Thomas A1 - Grimm, Volker A1 - Drechsler, Martin T1 - High-resolution PVA along large environmental gradients to model the combined effects of climate change and land use timing BT - lessons from the large marsh grasshopper JF - Ecological modelling : international journal on ecological modelling and systems ecology N2 - Both climate change and land use regimes affect the viability of populations, but they are often studied separately. Moreover, population viability analyses (PVAs) often ignore the effects of large environmental gradients and use temporal resolutions that are too coarse to take into account that different stages of a population's life cycle may be affected differently by climate change. Here, we present the High-resolution Large Environmental Gradient (HiLEG) model and apply it in a PVA with daily resolution based on daily climate projections for Northwest Germany. We used the large marsh grasshopper (LMG) as the target species and investigated (1) the effects of climate change on the viability and spatial distribution of the species, (2) the influence of the timing of grassland mowing on the species and (3) the interaction between the effects of climate change and grassland mowing. The stageand cohort-based model was run for the spatially differentiated environmental conditions temperature and soil moisture across the whole study region. We implemented three climate change scenarios and analyzed the population dynamics for four consecutive 20-year periods. Climate change alone would lead to an expansion of the regions suitable for the LMG, as warming accelerates development and due to reduced drought stress. However, in combination with land use, the timing of mowing was crucial, as this disturbance causes a high mortality rate in the aboveground life stages. Assuming the same date of mowing throughout the region, the impact on viability varied greatly between regions due to the different climate conditions. The regional negative effects of the mowing date can be divided into five phases: (1) In early spring, the populations were largely unaffected in all the regions; (2) between late spring and early summer, they were severely affected only in warm regions; (3) in summer, all the populations were severely affected so that they could hardly survive; (4) between late summer and early autumn, they were severely affected in cold regions; and (5) in autumn, the populations were equally affected across all regions. The duration and start of each phase differed slightly depending on the climate change scenario and simulation period, but overall, they showed the same pattern. Our model can be used to identify regions of concern and devise management recommendations. The model can be adapted to the life cycle of different target species, climate projections and disturbance regimes. We show with our adaption of the HiLEG model that high-resolution PVAs and applications on large environmental gradients can be reconciled to develop conservation strategies capable of dealing with multiple stressors. KW - Climate change KW - Land use KW - Population viability analysis KW - Stage-based model KW - High resolution KW - Environmental gradients Y1 - 2020 U6 - https://doi.org/10.1016/j.ecolmodel.2020.109355 SN - 0304-3800 SN - 1872-7026 VL - 440 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Offrede, Tom F. A1 - Jacobi, Jidde A1 - Rebernik, Teja A1 - de Jong, Lisanne A1 - Keulen, Stefanie A1 - Veenstra, Pauline A1 - Noiray, Aude A1 - Wieling, Martijn T1 - The impact of alcohol on L1 versus L2 JF - Language and Speech N2 - Alcohol intoxication is known to affect many aspects of human behavior and cognition; one of such affected systems is articulation during speech production. Although much research has revealed that alcohol negatively impacts pronunciation in a first language (L1), there is only initial evidence suggesting a potential beneficial effect of inebriation on articulation in a non-native language (L2). The aim of this study was thus to compare the effect of alcohol consumption on pronunciation in an L1 and an L2. Participants who had ingested different amounts of alcohol provided speech samples in their L1 (Dutch) and L2 (English), and native speakers of each language subsequently rated the pronunciation of these samples on their intelligibility (for the L1) and accent nativelikeness (for the L2). These data were analyzed with generalized additive mixed modeling. Participants' blood alcohol concentration indeed negatively affected pronunciation in L1, but it produced no significant effect on the L2 accent ratings. The expected negative impact of alcohol on L1 articulation can be explained by reduction in fine motor control. We present two hypotheses to account for the absence of any effects of intoxication on L2 pronunciation: (1) there may be a reduction in L1 interference on L2 speech due to decreased motor control or (2) alcohol may produce a differential effect on each of the two linguistic subsystems. KW - acute alcohol consumption KW - articulation KW - speech KW - bilingualism Y1 - 2020 U6 - https://doi.org/10.1177/0023830920953169 SN - 1756-6053 SN - 0023-8309 VL - 64 IS - 3 SP - 681 EP - 692 PB - SAGE Publications CY - Thousand Oaks ER -