TY - JOUR A1 - Clahsen, Harald A1 - Hansen, Detlef T1 - Profiling linguistic disability in German-speaking children JF - Assessing Grammar : the Languages of LARSP Y1 - 2012 SN - 978-1-8476-9639-7 U6 - https://doi.org/10.21832/9781847696397-007 SP - 77 EP - 91 PB - Multilingual Matters CY - Bristol ER - TY - JOUR A1 - Mackert, Jürgen T1 - Social Closure JF - Oxford Bibliographies N2 - “Social closure” is one of the most basic terms and concepts in sociology. Basically, closure refers to processes of drawing boundaries, constructing identities, and building communities in order to monopolize scarce resources for one’s own group, thereby excluding others from using them. Society is not a homogenous entity but is instead internally structured and subdivided by processes of social closure. Some social formations, such as groups, organizations, or institutions, may be open to everybody, provided they are capable of participation, while access to most others is limited due to certain criteria that either allow people to become members or exclude them from membership. Therefore, social closure is a ubiquitous, everyday phenomenon that can be observed in almost every sphere and place in the social world. Members of societies experience closure from the very beginning of their social life. To be excluded from certain groups starts at school, where presumably homogenous classes begin to subdivide into distinct peer groups or sports teams. Here, exclusion may be rather arbitrary, but the experience of having a door slammed in one’s face proceeds in cases, where inclusion depends on formal rules or preconditions. Access to private schools follows explicit rules and depends on financial capacities; access to university depends on a certificate or diploma, eventually from certain schools only; membership in a highly prestigious club depends on economic and social capital and the respective social networks; and finally, in the case of migration, people will have to be eligible for citizenship and pass the thorny path of naturalization. However, it is not just the enormous plurality of forms that makes social closure crucial for sociology. Rather, the process of closure of social relations—of groups, organizations, institutions, and even national societies—is the fundamental process of both “communal” (Vergemeinschaftung) and “associative” relationships (Vergesellschaftung), and neither would be possible without social closure. In this broad and fundamental sense, social closure is not restricted to processes in national societies. It even allows for understanding crucial processes of the way the social world is organized at the regional or global level. Y1 - 2012 U6 - https://doi.org/10.1093/obo/9780199756384-0084 PB - Oxford University CY - Oxford ER - TY - JOUR A1 - Faber, Eike T1 - Rezension zu: Jorge Martínez-Pinna Nieto: Las leyendas de fundación de Roma. De Eneas a Rómulo, Barcelona: Publicacions. Universitat de Barcelona, 2011. - 186 S. - ISBN 978-84-475-3502-6 JF - Sehepunkte : Rezensionsjournal für die Geschichtswissenschaften Y1 - 2012 UR - http://www.sehepunkte.de /2012/03/19737.html SN - 1618-6168 VL - 12 IS - 3 PB - Ludwig-Maximilians-Univ. CY - München ER - TY - THES A1 - Müller, Gesine T1 - Die Koloniale Karibik BT - zwischen Bipolarität und Multirelationalität, Tranzferprozesse in hispanophonen und frankophonen Literaturen (in 2 Teil Bänden) N2 - Werden nicht in der Karibik des 19. Jahrhunderts Phänomene und Prozesse vorweg-genommen, die heute erst ins Bewusstsein gelangen? Der Blick auf die kaleidoskopartige Welt der Karibik über literarische und kulturelle Transprozesse in jener Epoche erlaubt völlig neue Einsichten in die frühen Prozesse der kulturellen Globalisierung. Rassistische Diskurse, etablierte Modelle „weißer“ Abolitionisten, Erinnerungspolitiken und die bisher kaum wahrgenommene Rolle der haitianischen Revolution verbinden sich zu einem Amalgam, das unser gängiges Konzept einer genuin westlichen Moderne in Frage stellt. KW - Ethnische Beziehungen KW - Französisch KW - Geschichte 1800-1900 KW - Kolonialismus KW - Karibik KW - Kulturelle Identität KW - Literatur KW - Sprache Y1 - 2012 ER - TY - JOUR A1 - Apelojg, Benjamin T1 - Recruiting - Lass den Bauch sprechen JF - Personalwirtschaft : Magazin für Human Resources N2 - Personal auszuwählen ist eine verantwortungsvolle Aufgabe. Dabei ist es eigentlich ganz einfach: Bei der Entscheidung lohnt es sich, seinen Gefühlen zu vertrauen. KW - Personalauswahl KW - Bauchentscheidungen Y1 - 2012 SN - 0341-4698 VL - 39 IS - 5 SP - 59 EP - 62 PB - F.A.Z.Buisness Media CY - Frankfurt am Main ER - TY - BOOK A1 - Thim, Christof A1 - Gronau, Norbert A1 - Röchert-Voigt, Tanja A1 - Proske, Niels A1 - Heine, Moreen T1 - Organisation des Schutzes der kritischen Infrastruktur Wasserversorgung BT - Grundlagen und praktische Anwendung für Wasserversorger N2 - Die Erfüllung sicherheitsrelevanter Aufgaben, gerade im Bereich der Wasserversorgung, erfolgt immer vor dem Hintergrund des Schutzes der Kritischen Infrastruktur selbst und eines effektiven Bevölkerungsschutzes. Daher erfordert die Organisation des Schutzes eine über die betriebsbezogene Sichtweise hinausgehende überorganisatorische Betrachtung im Gesamtkontext zunehmender Verflechtung und Abhängigkeiten der Organisationen. Die vorliegende Broschüre richtet sich daher insbesondere an kleine und mittlere Betreiber Kritischer Infrastrukturen, insbesondere im Bereich der Wasserversorgung. Diese sollen in die Lage versetzt werden, eine anforderungsgerechte, skalierbare und vor allem ressourceneffiziente Schutzkonzepterstellung durchführen zu können. Y1 - 2012 SN - 978-3-942183-78-9 PB - Gito Verlag GmbH CY - Berlin ER - TY - GEN A1 - Lin, Chiao-I A1 - Khajooei, Mina A1 - Engel, Tilman A1 - Nair, Alexandra A1 - Heikkila, Mika A1 - Kaplick, Hannes A1 - Mayer, Frank T1 - The effect of chronic ankle instability on muscle activations in lower extremities T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - Background/Purpose Muscular reflex responses of the lower extremities to sudden gait disturbances are related to postural stability and injury risk. Chronic ankle instability (CAI) has shown to affect activities related to the distal leg muscles while walking. Its effects on proximal muscle activities of the leg, both for the injured- (IN) and uninjured-side (NON), remain unclear. Therefore, the aim was to compare the difference of the motor control strategy in ipsilateral and contralateral proximal joints while unperturbed walking and perturbed walking between individuals with CAI and matched controls. Materials and methods In a cross-sectional study, 13 participants with unilateral CAI and 13 controls (CON) walked on a split-belt treadmill with and without random left- and right-sided perturbations. EMG amplitudes of muscles at lower extremities were analyzed 200 ms after perturbations, 200 ms before, and 100 ms after (Post100) heel contact while walking. Onset latencies were analyzed at heel contacts and after perturbations. Statistical significance was set at alpha≤0.05 and 95% confidence intervals were applied to determine group differences. Cohen’s d effect sizes were calculated to evaluate the extent of differences. Results Participants with CAI showed increased EMG amplitudes for NON-rectus abdominus at Post100 and shorter latencies for IN-gluteus maximus after heel contact compared to CON (p<0.05). Overall, leg muscles (rectus femoris, biceps femoris, and gluteus medius) activated earlier and less bilaterally (d = 0.30–0.88) and trunk muscles (bilateral rectus abdominus and NON-erector spinae) activated earlier and more for the CAI group than CON group (d = 0.33–1.09). Conclusion Unilateral CAI alters the pattern of the motor control strategy around proximal joints bilaterally. Neuromuscular training for the muscles, which alters motor control strategy because of CAI, could be taken into consideration when planning rehabilitation for CAI. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 712 KW - Electromyography KW - Hip KW - Skeletal joints KW - Knees KW - Legs KW - Musculoskeletal injury KW - Walking KW - Ankles Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-515632 SN - 1866-8364 ER - TY - GEN A1 - Ebert, Birgitta E. A1 - Lamprecht, Anna-Lena A1 - Steffen, Bernhard A1 - Blank, Lars M. T1 - Flux-P BT - automating metabolic flux analysis T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Quantitative knowledge of intracellular fluxes in metabolic networks is invaluable for inferring metabolic system behavior and the design principles of biological systems. However, intracellular reaction rates can not often be calculated directly but have to be estimated; for instance, via 13C-based metabolic flux analysis, a model-based interpretation of stable carbon isotope patterns in intermediates of metabolism. Existing software such as FiatFlux, OpenFLUX or 13CFLUX supports experts in this complex analysis, but requires several steps that have to be carried out manually, hence restricting the use of this software for data interpretation to a rather small number of experiments. In this paper, we present Flux-P as an approach to automate and standardize 13C-based metabolic flux analysis, using the Bio-jETI workflow framework. Exemplarily based on the FiatFlux software, it demonstrates how services can be created that carry out the different analysis steps autonomously and how these can subsequently be assembled into software workflows that perform automated, high-throughput intracellular flux analysis of high quality and reproducibility. Besides significant acceleration and standardization of the data analysis, the agile workflow-based realization supports flexible changes of the analysis workflows on the user level, making it easy to perform custom analyses. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1054 KW - 13C metabolic flux analysis KW - MFA KW - high-throughput analysis KW - scientific workflows KW - workflow management KW - Bio-jETI Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-476696 SN - 1866-8372 IS - 1054 SP - 872 EP - 890 ER - TY - JOUR A1 - Saupe, Achim T1 - Zur Kritik des Zeugen in der Konstitutionsphase der modernen Geschichtswissenschaft JF - Die Geburt des Zeitzeugen nach 1945 Y1 - 2012 SN - 978-3-8353-1036-0 SP - 71 EP - 92 PB - Wallstein CY - Göttingen ER - TY - BOOK ED - Sabrow, Martin ED - Frei, Norbert T1 - Die Geburt des Zeitzeugen nach 1945 T3 - Geschichte der Gegenwart / Beiträge zur Geschichte des 20. Jahrhunderts ; 414 Y1 - 2012 SN - 978-3-8353-1036-0 PB - Wallstein CY - Göttingen ER - TY - JOUR A1 - Sabrow, Martin ED - Sabrow, Martin ED - Frei, Norbert T1 - Der Zeitzeuge als Wanderer zwischen zwei Welten JF - Die Geburt des Zeitzeugen nach 1945 Y1 - 2012 SN - 978-3-8353-1036-0 SP - 13 EP - 32 PB - Wallstein CY - Göttingen ER - TY - GEN A1 - Caliendo, Marco A1 - Hogenacker, Jens T1 - The German labor market after the Great Recession BT - successful reforms and future challenges T2 - Postprints der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe N2 - The reaction of the German labor market to the Great Recession 2008/09 was relatively mild – especially compared to other countries. The reason lies not only in the specific type of the recession – which was favorable for the German economy structure – but also in a series of labor market reforms initiated between 2002 and 2005 altering, inter alia, labor supply incentives. However, irrespective of the mild response to the Great Recession, there are a number of substantial future challenges the German labor market will soon have to face. Female labor supply still lies well below that of other countries and a massive demographic change over the next 50 years will have substantial effects on labor supply as well as the pension system. In addition, due to a skill-biased technological change over the next decades, firms will face problems of finding employees with adequate skills. The aim of this paper is threefold. First, we outline why the German labor market reacted in such a mild fashion, describe current economic trends of the labor market in light of general trends in the European Union, and reveal some of the main associated challenges. Thereafter, the paper analyzes recent reforms of the main institutional settings of the labor market which influence labor supply. Finally, based on the status quo of these institutional settings, the paper gives a brief overview of strategies to combat adequately the challenges in terms of labor supply and to ensure economic growth in the future. T3 - Zweitveröffentlichungen der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe - 129 KW - unemployment KW - labor force participation KW - Labor supply KW - benefit systems KW - public policy Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-435195 SN - 1867-5808 IS - 129 ER - TY - GEN A1 - Krippendorff, Ben-Fillippo A1 - Oyarzún, Diego A. A1 - Huisinga, Wilhelm T1 - Predicting the F(ab)-mediated effect of monoclonal antibodies in vivo by combining cell-level kinetic and pharmacokinetic modelling T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Cell-level kinetic models for therapeutically relevant processes increasingly benefit the early stages of drug development. Later stages of the drug development processes, however, rely on pharmacokinetic compartment models while cell-level dynamics are typically neglected. We here present a systematic approach to integrate cell-level kinetic models and pharmacokinetic compartment models. Incorporating target dynamics into pharmacokinetic models is especially useful for the development of therapeutic antibodies because their effect and pharmacokinetics are inherently interdependent. The approach is illustrated by analysing the F(ab)-mediated inhibitory effect of therapeutic antibodies targeting the epidermal growth factor receptor. We build a multi-level model for anti-EGFR antibodies by combining a systems biology model with in vitro determined parameters and a pharmacokinetic model based on in vivo pharmacokinetic data. Using this model, we investigated in silico the impact of biochemical properties of anti-EGFR antibodies on their F(ab)-mediated inhibitory effect. The multi-level model suggests that the F(ab)-mediated inhibitory effect saturates with increasing drug-receptor affinity, thereby limiting the impact of increasing antibody affinity on improving the effect. This indicates that observed differences in the therapeutic effects of high affinity antibodies in the market and in clinical development may result mainly from Fc-mediated indirect mechanisms such as antibody-dependent cell cytotoxicity. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 958 KW - cell-level kinetics KW - pharmacokinetic models KW - therapeutic proteins KW - EGFR Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-431051 SN - 1866-8372 IS - 958 SP - 125 EP - 139 ER - TY - GEN A1 - Larhlimi, Abdelhalim A1 - David, Laszlo A1 - Selbig, Joachim A1 - Bockmayr, Alexander T1 - F2C2 BT - a fast tool for the computation of flux coupling in genome-scale metabolic networks T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Background: Flux coupling analysis (FCA) has become a useful tool in the constraint-based analysis of genome-scale metabolic networks. FCA allows detecting dependencies between reaction fluxes of metabolic networks at steady-state. On the one hand, this can help in the curation of reconstructed metabolic networks by verifying whether the coupling between reactions is in agreement with the experimental findings. On the other hand, FCA can aid in defining intervention strategies to knock out target reactions. Results: We present a new method F2C2 for FCA, which is orders of magnitude faster than previous approaches. As a consequence, FCA of genome-scale metabolic networks can now be performed in a routine manner. Conclusions: We propose F2C2 as a fast tool for the computation of flux coupling in genome-scale metabolic networks. F2C2 is freely available for non-commercial use at https://sourceforge.net/projects/f2c2/files/. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 921 KW - balance analysis KW - reconstruction KW - pathways KW - models KW - metabolic network KW - couple reaction KW - reversible reaction KW - linear programming problem KW - coupling relationship Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-432431 SN - 1866-8372 IS - 921 ER - TY - GEN A1 - Lenhard, Michael T1 - All's well that ends well BT - arresting cell proliferation in leaves T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - The transition from cell proliferation to cell expansion is critical for determining leaf size. Andriankaja et al. (2012) demonstrate that in leaves of dicotyledonous plants, a basal proliferation zone is maintained for several days before abruptly disappearing, and that chloroplast differentiation is required to trigger the onset of cell expansion. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 906 KW - arabidopsis-thaliana KW - genetic-control KW - growth KW - size KW - curvature Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-438035 SN - 1866-8372 IS - 906 SP - 9 EP - 11 ER - TY - GEN A1 - Dallmeyer, Anne A1 - Claussen, Martin A1 - Wang, Yongbo A1 - Herzschuh, Ulrike T1 - Spatial variability of Holocene changes in the annual precipitation pattern BT - a model-data synthesis for the Asian monsoon region T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - This study provides a detailed analysis of the mid-Holocene to present-day precipitation change in the Asian monsoon region. We compare for the first time results of high resolution climate model simulations with a standardised set of mid-Holocene moisture reconstructions. Changes in the simulated summer monsoon characteristics (onset, withdrawal, length and associated rainfall) and the mechanisms causing the Holocene precipitation changes are investigated. According to the model, most parts of the Indian subcontinent received more precipitation (up to 5 mm/day) at mid-Holocene than at present-day. This is related to a stronger Indian summer monsoon accompanied by an intensified vertically integrated moisture flux convergence. The East Asian monsoon region exhibits local inhomogeneities in the simulated annual precipitation signal. The sign of this signal depends on the balance of decreased pre-monsoon and increased monsoon precipitation at mid-Holocene compared to present-day. Hence, rainfall changes in the East Asian monsoon domain are not solely associated with modifications in the summer monsoon circulation but also depend on changes in the mid-latitudinal westerly wind system that dominates the circulation during the pre-monsoon season. The proxy-based climate reconstructions confirm the regional dissimilarities in the annual precipitation signal and agree well with the model results. Our results highlight the importance of including the pre-monsoon season in climate studies of the Asian monsoon system and point out the complex response of this system to the Holocene insolation forcing. The comparison with a coarse climate model simulation reveals that this complex response can only be resolved in high resolution simulations. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 905 KW - Asian monsoon KW - holocene KW - precipitation KW - climate modelling KW - moisture reconstructions Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-432771 SN - 1866-8372 IS - 905 ER - TY - GEN A1 - Cheng, Lisa Lai-Shen A1 - Vicente, Luis T1 - Verb doubling in Mandarin Chinese T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - This article examines two so-far-understudied verb doubling constructions in Mandarin Chinese, viz., verb doubling clefts and verb doubling lian…dou. We show that these constructions have the same internal syntax as regular clefts and lian…dou sentences, the doubling effect being epiphenomenal; therefore, we classify them as subtypes of the general cleft and lian…dou constructions, respectively, rather than as independent constructions. Additionally, we also show that, as in many other languages with comparable constructions, the two instances of the verb are part of a single movement chain, which has the peculiarity of allowing Spell-Out of more than one link. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 629 KW - Mandarin Chinese KW - verb doubling KW - verb movement KW - cleft KW - lian…dou Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-436880 SN - 1866-8364 IS - 629 SP - 1 EP - 37 ER - TY - GEN A1 - Powell, Anahid E. A1 - Lenhard, Michael T1 - Control of organ size in plants T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - The size of plant organs, such as leaves and flowers, is determined by an interaction of genotype and environmental influences. Organ growth occurs through the two successive processes of cell proliferation followed by cell expansion. A number of genes influencing either or both of these processes and thus contributing to the control of final organ size have been identified in the last decade. Although the overall picture of the genetic regulation of organ size remains fragmentary, two transcription factor/microRNA-based genetic pathways are emerging in the control of cell proliferation. However, despite this progress, fundamental questions remain unanswered, such as the problem of how the size of a growing organ could be monitored to determine the appropriate time for terminating growth. While genetic analysis will undoubtedly continue to advance our knowledge about size control in plants, a deeper understanding of this and other basic questions will require including advanced live-imaging and mathematical modeling, as impressively demonstrated by some recent examples. This should ultimately allow the comparison of the mechanisms underlying size control in plants and in animals to extract common principles and lineage-specific solutions. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 898 KW - BHLH transcription factor KW - genome-wide association KW - arabidopsis-thaliana KW - cell-proliferation KW - leaf development KW - developing leaves KW - petal growth KW - gene family KW - tor kinase KW - auxin Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-438029 SN - 1866-8372 IS - 898 ER - TY - GEN A1 - Wojcinski, Sebastian A1 - Dupont, Jennifer A1 - Schmidt, Werner A1 - Cassel, Michael A1 - Hillemanns, Peter T1 - Real-time ultrasound elastography in 180 axillary lymph nodes BT - elasticity distribution in healthy lymph nodes and prediction of breast cancer metastases T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - Background To determine the general appearance of normal axillary lymph nodes (LNs) in real-time tissue sonoelastography and to explore the method′s potential value in the prediction of LN metastases. Methods Axillary LNs in healthy probands (n=165) and metastatic LNs in breast cancer patients (n=15) were examined with palpation, B-mode ultrasound, Doppler and sonoelastography (assessment of the elasticity of the cortex and the medulla). The elasticity distributions were compared and sensitivity (SE) and specificity (SP) were calculated. In an exploratory analysis, positive and negative predictive values (PPV, NPV) were calculated based upon the estimated prevalence of LN metastases in different risk groups. Results In the elastogram, the LN cortex was significantly harder than the medulla in both healthy (p=0.004) and metastatic LNs (p=0.005). Comparing healthy and metastatic LNs, there was no difference in the elasticity distribution of the medulla (p=0.281), but we found a significantly harder cortex in metastatic LNs (p=0.006). The SE of clinical examination, B-mode ultrasound, Doppler ultrasound and sonoelastography was revealed to be 13.3%, 40.0%, 14.3% and 60.0%, respectively, and SP was 88.4%, 96.8%, 95.6% and 79.6%, respectively. The highest SE was achieved by the disjunctive combination of B-mode and elastographic features (cortex >3mm in B-mode or blue cortex in the elastogram, SE=73.3%). The highest SP was achieved by the conjunctive combination of B-mode ultrasound and elastography (cortex >3mm in B-mode and blue cortex in the elastogram, SP=99.3%). Conclusions Sonoelastography is a feasible method to visualize the elasticity distribution of LNs. Moreover, sonoelastography is capable of detecting elasticity differences between the cortex and medulla, and between metastatic and healthy LNs. Therefore, sonoelastography yields additional information about axillary LN status and can improve the PPV, although this method is still experimental. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 626 KW - breast ultrasound KW - axillary lymph nodes KW - sonoelastography KW - real-time tissue elastography KW - cancer detection KW - elasticity imaging KW - HI-RTE KW - lymph node metastases Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-431584 SN - 1866-8364 IS - 626 ER - TY - GEN A1 - Jing, Runchun A1 - Ambrose, Michael A. A1 - Knox, Maggie R. A1 - Smykal, Petr A1 - Hybl, Miroslav A1 - Ramos, Á. A1 - Caminero, Constantino A1 - Burstin, Judith A1 - Duc, Gerard A1 - van Soest, L. J. M. A1 - Święcicki, W. K. A1 - Pereira, M. Graca A1 - Vishnyakova, Margarita A1 - Davenport, Guy F. A1 - Flavell, Andrew J. A1 - Ellis, T. H. Noel T1 - Genetic diversity in European Pisum germplasm collections T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - The distinctness of, and overlap between, pea genotypes held in several Pisum germplasm collections has been used to determine their relatedness and to test previous ideas about the genetic diversity of Pisum. Our characterisation of genetic diversity among 4,538 Pisum accessions held in 7 European Genebanks has identified sources of novel genetic variation, and both reinforces and refines previous interpretations of the overall structure of genetic diversity in Pisum. Molecular marker analysis was based upon the presence/absence of polymorphism of retrotransposon insertions scored by a high-throughput microarray and SSAP approaches. We conclude that the diversity of Pisum constitutes a broad continuum, with graded differentiation into sub-populations which display various degrees of distinctness. The most distinct genetic groups correspond to the named taxa while the cultivars and landraces of Pisum sativum can be divided into two broad types, one of which is strongly enriched for modern cultivars. The addition of germplasm sets from six European Genebanks, chosen to represent high diversity, to a single collection previously studied with these markers resulted in modest additions to the overall diversity observed, suggesting that the great majority of the total genetic diversity collected for the Pisum genus has now been described. Two interesting sources of novel genetic variation have been identified. Finally, we have proposed reference sets of core accessions with a range of sample sizes to represent Pisum diversity for the future study and exploitation by researchers and breeders. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 871 KW - germplasm collection KW - insertion polymorphism KW - retrotransposon insertion KW - broad continuum KW - SSAP marker Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-434743 SN - 1866-8372 IS - 871 SP - 367 EP - 380 ER - TY - GEN A1 - Adam, Jos J. A1 - Bovend'Eerdt, Thamar J. H. A1 - Dooren, Fleur E. P. van A1 - Fischer, Martin H. A1 - Pratt, Jay T1 - The closer the better BT - hand proximity dynamically affects letter recognition accuracy T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - A growing literature has suggested that processing of visual information presented near the hands is facilitated. In this study, we investigated whether the near-hands superiority effect also occurs with the hands moving. In two experiments, participants performed a cyclical bimanual movement task requiring concurrent visual identification of briefly presented letters. For both the static and dynamic hand conditions, the results showed improved letter recognition performance with the hands closer to the stimuli. The finding that the encoding advantage for near-hand stimuli also occurred with the hands moving suggests that the effect is regulated in real time, in accordance with the concept of a bimodal neural system that dynamically updates hand position in external space. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 607 KW - perception and action Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-432963 SN - 1866-8364 IS - 607 SP - 1533 EP - 1538 ER - TY - GEN A1 - Krügel, André A1 - Vitu, Françoise A1 - Engbert, Ralf T1 - Fixation positions after skipping saccades BT - a single space makes a large difference T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - During reading, saccadic eye movements are generated to shift words into the center of the visual field for lexical processing. Recently, Krugel and Engbert (Vision Research 50:1532-1539, 2010) demonstrated that within-word fixation positions are largely shifted to the left after skipped words. However, explanations of the origin of this effect cannot be drawn from normal reading data alone. Here we show that the large effect of skipped words on the distribution of within-word fixation positions is primarily based on rather subtle differences in the low-level visual information acquired before saccades. Using arrangements of "x" letter strings, we reproduced the effect of skipped character strings in a highly controlled single-saccade task. Our results demonstrate that the effect of skipped words in reading is the signature of a general visuomotor phenomenon. Moreover, our findings extend beyond the scope of the widely accepted range-error model, which posits that within-word fixation positions in reading depend solely on the distances of target words. We expect that our results will provide critical boundary conditions for the development of visuomotor models of saccade planning during reading. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 856 KW - eye movements KW - reading KW - motor control KW - skipping Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-432887 SN - 1866-8372 IS - 856 SP - 1556 EP - 1561 ER - TY - GEN A1 - Kleessen, Sabrina A1 - Nikoloski, Zoran T1 - Dynamic regulatory on/off minimization for biological systems under internal temporal perturbations T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - Background: Flux balance analysis (FBA) together with its extension, dynamic FBA, have proven instrumental for analyzing the robustness and dynamics of metabolic networks by employing only the stoichiometry of the included reactions coupled with adequately chosen objective function. In addition, under the assumption of minimization of metabolic adjustment, dynamic FBA has recently been employed to analyze the transition between metabolic states. Results: Here, we propose a suite of novel methods for analyzing the dynamics of (internally perturbed) metabolic networks and for quantifying their robustness with limited knowledge of kinetic parameters. Following the biochemically meaningful premise that metabolite concentrations exhibit smooth temporal changes, the proposed methods rely on minimizing the significant fluctuations of metabolic profiles to predict the time-resolved metabolic state, characterized by both fluxes and concentrations. By conducting a comparative analysis with a kinetic model of the Calvin-Benson cycle and a model of plant carbohydrate metabolism, we demonstrate that the principle of regulatory on/off minimization coupled with dynamic FBA can accurately predict the changes in metabolic states. Conclusions: Our methods outperform the existing dynamic FBA-based modeling alternatives, and could help in revealing the mechanisms for maintaining robustness of dynamic processes in metabolic networks over time. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 852 KW - metabolic network KW - metabolite concentration KW - flux rate KW - flux balance analysis KW - qualitative comparative analysis Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-431128 SN - 1866-8372 IS - 852 ER - TY - GEN A1 - Hische, Manuela A1 - Larhlimi, Abdelhalim A1 - Schwarz, Franziska A1 - Fischer-Rosinský, Antje A1 - Bobbert, Thomas A1 - Assmann, Anke A1 - Catchpole, Gareth S. A1 - Pfeiffer, Andreas F. H. A1 - Willmitzer, Lothar A1 - Selbig, Joachim A1 - Spranger, Joachim T1 - A distinct metabolic signature predictsdevelopment of fasting plasma glucose T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - Background High blood glucose and diabetes are amongst the conditions causing the greatest losses in years of healthy life worldwide. Therefore, numerous studies aim to identify reliable risk markers for development of impaired glucose metabolism and type 2 diabetes. However, the molecular basis of impaired glucose metabolism is so far insufficiently understood. The development of so called 'omics' approaches in the recent years promises to identify molecular markers and to further understand the molecular basis of impaired glucose metabolism and type 2 diabetes. Although univariate statistical approaches are often applied, we demonstrate here that the application of multivariate statistical approaches is highly recommended to fully capture the complexity of data gained using high-throughput methods. Methods We took blood plasma samples from 172 subjects who participated in the prospective Metabolic Syndrome Berlin Potsdam follow-up study (MESY-BEPO Follow-up). We analysed these samples using Gas Chromatography coupled with Mass Spectrometry (GC-MS), and measured 286 metabolites. Furthermore, fasting glucose levels were measured using standard methods at baseline, and after an average of six years. We did correlation analysis and built linear regression models as well as Random Forest regression models to identify metabolites that predict the development of fasting glucose in our cohort. Results We found a metabolic pattern consisting of nine metabolites that predicted fasting glucose development with an accuracy of 0.47 in tenfold cross-validation using Random Forest regression. We also showed that adding established risk markers did not improve the model accuracy. However, external validation is eventually desirable. Although not all metabolites belonging to the final pattern are identified yet, the pattern directs attention to amino acid metabolism, energy metabolism and redox homeostasis. Conclusions We demonstrate that metabolites identified using a high-throughput method (GC-MS) perform well in predicting the development of fasting plasma glucose over several years. Notably, not single, but a complex pattern of metabolites propels the prediction and therefore reflects the complexity of the underlying molecular mechanisms. This result could only be captured by application of multivariate statistical approaches. Therefore, we highly recommend the usage of statistical methods that seize the complexity of the information given by high-throughput methods. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 850 KW - prediction KW - fasting glucose KW - type 2 diabetes KW - metabolomics KW - plasma KW - random forest KW - metabolite KW - regression KW - biomarker Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-427400 SN - 1866-8372 IS - 850 ER - TY - JOUR A1 - Günther, Oliver A1 - Mangelsdorf, Birgit A1 - Mitzner, Rolf A1 - Loschelder, Wolfgang A1 - Peter, Andreas A1 - Eckert, Barbara A1 - Mikelskis, Helmut A1 - Klein, Alfred A1 - Kirsch, Bärbel A1 - Edelstein, Wolfgang A1 - Thomas, Grünewald A1 - Thomas, Pösl A1 - Wagner, Dieter A1 - Winskowski, Friedrich A1 - Schad, Martina A1 - Frey, Anne A1 - Bickenbach, Wulf A1 - Madani, Roya A1 - Olaka, Lydia T1 - Portal alumni T2 - Das Ehemaligen-Magazin der Universität Potsdam N2 - Das zurückliegende Jahr stand an der Universität Potsdam auch im Zeichen des zwanzigjährigen Jubiläums der Hochschule. Am 15. Juli 1991, wurde sie gegründet und während einer Festwoche feierten Professorinnen und Professoren, Mitarbeiterinnen, Mitarbeiter und Studierende dieses Jubiläum gebührend. Seit der Gründung der größten brandenburgischen Hochschule sind wissenschaftliches Renommee, Ansehen und Attraktivität stetig gewachsen. Gerade in den letzten Jahren hat sie ihr Profil geschärft. Vor allem die Kognitions-, die Geo- und Biowissenschaften sind hier zu nennen. Aber auch die Lehrerbildung besitzt einen hohen Stellenwert. International anerkannte Forschungsbereiche, Wissenschaftspreise, eine erfolgreiche Drittmittelbilanz und nicht zuletzt die bauliche Entwicklung an allen drei Standorten sind sichtbare Indikatoren für die erfolgreiche Entwicklung, die die Universität Potsdam in den letzten zwei Jahrzehnten durchlaufen hat. Die drei ehemaligen Präsidenten sowie verschiedene andere Protagonisten werfen in dieser Ausgabe der Portal Alumni einen Blick auf unterschiedliche Aspekte der zurückliegenden Entwicklung der Universität. Vom Erfolg der Universität zeugt auch die wachsende Zahl der Absolventinnen und Absolventen, die die Universität verlassen. Portal Alumni stellt in der vorliegenden Ausgabe deshalb Absolventen und deren universitäre und berufliche Lebenswege genauer vor und lässt damit zugleich kaleidoskopartig 20 Jahre Studium an der Universität Potsdam Revue passieren. T3 - Portal alumni : das Ehemaligen-Magazin der Universität Potsdam - 9/2012 Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-444943 SN - 1613-2343 IS - 9 ER - TY - JOUR A1 - Prengel, Annedore T1 - Erkunden und erfinden BT - Praxisforschung als Grundlage professionellen pädagogischen Handelns mit Kindern JF - Methoden der Kindheitsforschung : ein Überblick über Forschungszugänge zur kindlichen Perspektive Y1 - 2012 SN - 978-3-7799-1553-9 SP - 292 EP - 305 PB - Beltz Juventa CY - Weinheim ET - 2., überarb. ER - TY - JOUR A1 - Oswald, Hans T1 - Geleitwort JF - Methoden der Kindheitsforschung : ein Überblick über Forschungszugänge zur kindlichen Perspektive Y1 - 2012 SN - 978-3-7799-1553-9 SP - 13 EP - 21 PB - Beltz Juventa CY - Weinheim ER - TY - JOUR A1 - Prengel, Annedore T1 - Respekt und Missachtung BT - Interaktionen zwischen LehrerInnen und SchülerInnen JF - Zerstörerische Vorgänge ; Missachtung und sexuelle Gewalt gegen Kinder und Jugendliche in Institutionen Y1 - 2012 SN - 978-3-7799-2818-8 SP - 178 EP - 194 PB - Beltz Juventa CY - Weinheim ER - TY - JOUR A1 - Gräf, Ralph A1 - Seckler, Robert A1 - Hagemann, Alfred A1 - D'Aprile, Iwan-Michelangelo A1 - Schulte, Christoph A1 - Zimmermann, Matthias A1 - Blom, Hans A1 - Horn-Conrad, Antje A1 - Kampe, Heike A1 - Jäger, Sophie A1 - Haase, Jana A1 - Eckardt, Barbara A1 - Priebs-Tröger, Astrid A1 - Walz, Bernd T1 - Portal Wissen = Raum BT - Das Forschungsmagazin der Universität Potsdam N2 - Mit „Portal Wissen“ laden wir Sie ein, die Forschung an der Universität Potsdam zu entdecken und in ihrer Vielfalt kennenzulernen. In der ersten Ausgabe dreht sich alles um „Räume“. Räume, in denen geforscht wird, solche, die es zu erforschen gilt, andere, die durch Wissenschaft zugänglich oder erschlossen werden, aber auch Räume, die Wissenschaft braucht, um sich entfalten zu können. Forschung vermisst Räume: „Wissenschaft wird von Menschen gemacht“, schrieb der Physiker Werner Heisenberg. Umgekehrt lässt sich sagen: Wissenschaft macht Menschen, widmet sich ihnen, beeinflusst sie. Dieser Beziehung ist „Portal Wissen“ nachgegangen. Wir haben Wissenschaftler getroffen, sie gefragt, wie aus ihren Fragen Projekte entstehen, haben sie auf dem oft verschlungenen Weg zum Ziel begleitet. Ein besonderes Augenmerk dieses Heftes gilt den „Kulturellen Begegnungsräumen“, denen ein eigener Profilbereich der Forschung an der Universität Potsdam gewidmet ist. Forschung hat Räume: Labore, Bibliotheken, Gewächshäuser oder Archive – hier ist Wissenschaft zu Liebe Leserinnen und Leser, Hause. All diese Orte sind so einzigartig wie die Wissenschaftler, die in ihnen arbeiten, oder die Untersuchungen, die hier stattfinden. Erst die Vision davon, wie ein Problem zu lösen ist, macht aus einfachen Zimmern „Laborräume“. Wir haben ihre Türen geöffnet, um zu zeigen, was – und wer – sich dahinter befindet. Forschung eröffnet Räume: Wenn Wissenschaft erfolgreich ist, bewegt sie uns, bringt uns voran. Auf dem Weg einer wissenschaftlichen Erkenntnis aus dem Labor in den Alltag stehen mitunter Hürden, die meist nicht auf den ersten Blick zu erkennen sind. Auf jeden Fall aber ist ihre Anwendung erster Ausgangspunkt von Wissenschaft, Antrieb und Motivation jedes Forschers. „Portal Wissen“ zeigt, welche „Praxisräume“ sich aus der Übersetzung von Forschungsresultaten ergeben. Dort, wo wir es unbedingt erwarten, und dort, wo vielleicht nicht. Forschung erschließt Räume: Bei Expeditionen, Feldversuchen und Exkursionen wird nahezu jede Umgebung zum mobilen Labor. So eröffnet Wissenschaft Zugänge auch zu Orten, die auf vielfach andere Weise verschlossen oder unzugänglich scheinen. Wir haben uns in Forscher- Reisetaschen gemogelt, um bei Entdeckungsreisen dabei zu sein, die weit weg – vor allem nach Afrika – führen. Zugleich haben wir beobachtet, wie „Entwicklungsräume“ sich auch von Potsdam aus erschließen lassen oder zumindest ihre Vermessung in Potsdam beginnen kann. Forschung braucht Räume: Wissenschaft hat zwei Geschlechter, endlich. Noch nie waren so viele Frauen in der Forschung tätig wie derzeit. Ein Grund zum Ausruhen ist dies gleichwohl nicht. Deutschlandweit ist aktuell nur jede fünfte Professur von einer Frau besetzt. „Portal Wissen“ schaut, welche „Entwicklungsräume“ Frauen sich in der Wissenschaft, aber auch darüber hinaus geschaffen haben. Und wo sie ihnen verwehrt werden. Wir wünschen Ihnen eine anregende Lektüre und dass auch Sie einen Raum finden, der Sie inspiriert. Prof. Dr. Robert Seckler Vizepräsident für Forschung und wissenschaftlichen Nachwuchs T3 - Portal Wissen: Das Forschungsmagazin der Universität Potsdam [Deutsche Ausgabe] - 01/2012 Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440785 SN - 2194-4237 IS - 01/2012 ER - TY - JOUR A1 - Musil, Andreas A1 - Eckardt, Barbara A1 - Jäger, Sophie A1 - Zimmermann, Matthias A1 - Pohlenz, Philipp A1 - Mauermeister, Sylvi A1 - Büstrin, Klaus A1 - Rost, Sophia A1 - Horn-Conrad, Antje A1 - Görlich, Petra T1 - Portal = Zu Hause in der Fremde: Mobilität im Wissenschaftsbetrieb BT - Das Potsdamer Universitätsmagazin N2 - Aus dem Inhalt: - Zu Hause in der Fremde: Mobilität im Wissenschaftsbetrieb - Die Kunst des Hörens - Verführerisch bunt T3 - Portal: Das Potsdamer Universitätsmagazin - 04/2012 Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440496 SN - 1618-6893 IS - 04/2012 ER - TY - JOUR A1 - Günther, Oliver A1 - Görlich, Petra A1 - Hoffmann, Florian A1 - Zimmermann, Matthias A1 - Jäger, Sophie A1 - Weise, Aileen A1 - Wiehn, Tanja A1 - Eckardt, Barbara A1 - Rost, Sophia A1 - Klein, Armin A1 - Eulenfeld, Sophie T1 - Portal = Zwischen Hörsaal und Trainingsplatz: Studium und Leistungssport BT - Das Potsdamer Universitätsmagazin N2 - Aus dem Inhalt: - Zwischen Hörsaal und Trainingsplatz: Studium und Leistungssport - Studieren sans souci - Brisante Farbenlehre T3 - Portal: Das Potsdamer Universitätsmagazin - 03/2012 Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440488 SN - 1618-6893 IS - 03/2012 ER - TY - JOUR A1 - Schründer-Lenzen, Agi A1 - Zimmermann, Matthias A1 - Görlich, Petra A1 - Horn-Conrad, Antje A1 - Geller, Katrin A1 - Eckardt, Barbara A1 - Hoffmann, Florian A1 - Pyanoe, Steffi A1 - Kampe, Heike A1 - Jäger, Sophie A1 - Reinhardt, Ragna T1 - Portal = Zwischen Freiheit und Verantwortung: Ethik in der Forschung BT - Das Potsdamer Universitätsmagazin N2 - Aus dem Inhalt: - Zwischen Freiheit und Verantwortung: Ethik in der Forschung - Die Grenzen der Grammatik - Ein Bild von einem Mann T3 - Portal: Das Potsdamer Universitätsmagazin - 02/2012 Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440475 SN - 1618-6893 IS - 02/2012 ER - TY - JOUR A1 - D'Aprile, Iwan-Michelangelo A1 - Zimmermann, Matthias A1 - Jäger, Sophie A1 - Horn-Conrad, Antje A1 - Eckardt, Barbara A1 - Voigt, Juliane A1 - Görlich, Petra T1 - Portal = Friedrich der Große: Zwischen Legende und Wirklichkeit BT - Das Potsdamer Universitätsmagazin N2 - Aus dem Inhalt: - Friedrich der Große: Zwischen Legende und Wirklichkeit - Inseln im Büchermeer - Wenn das Universum beschleunigt expandiert T3 - Portal: Das Potsdamer Universitätsmagazin - 01/2012 Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440464 SN - 1618-6893 IS - 01/2012 ER - TY - JOUR A1 - Mitsch, Wolfgang T1 - Strafrecht, Strafprozessrecht und das Recht der Ordnungswidrigkeiten in der Verfassung des Landes Brandenburg JF - 20 Jahre Landesverfassung : Festschrift des Landtages Brandenburg Y1 - 2012 SN - 978-3-428-13920-0 SP - 85 EP - 94 PB - Duncker & Humblot CY - Berlin ER - TY - JOUR A1 - Schulz, Götz T1 - Die Stellung des Sports in der Verfassung Brandenburgs JF - 20 Jahre Landesverfassung : Festschrift des Landtages Brandenburg Y1 - 2012 SN - 978-3-428-13920-0 SP - 71 EP - 84 PB - Duncker & Humblot CY - Berlin ER - TY - BOOK A1 - Kleger, Heinz T1 - Jeder nach seiner Façon BT - Toleranz als Streitfeld : ein Satz als Anstoß zum Nachdenken : aus Anlass des 300. Geburtstages des ´Philosophenkönigs´ Friedrich II. N2 - Der 300. Geburtstag Friedrich II ist 2012 im Land Brandenburg und der Stadt Potsdam allgegenwärtig. Zahlreiche Veranstaltungen beschäftigen sich mit dem Leben und Wirken des Königs auf vielfältige Art und Weise. Sein sympathischster Satz „Jeder soll nach seiner Façon selig werden“ – gemäß seiner Religion, war der Anstoß, sich im Jubiläums-Jahr mit Friedrich II abseits touristischer Erlebnisangebote auseinanderzusetzen. Dabei geht es nicht um Friedrich-Exegese, wohl aber um seine Philosophie von Sanssouci und seine politische Theorie. Den abgekürzten Satz „Jeder nach seiner Façon“ interpretieren wir inzwischen individualistisch. Insbesondere die Versprechen der Urbanität führen zu einer rasanten Verstädterung der Welt, welche noch nie gesehene Herausforderungen an die demokratische Regierbarkeit stellt. Je subjektiver Glück als Abenteuer mit Chancen und Risiken verstanden wird, desto mehr wird urbane Toleranz zu einer eminenten Leistung menschlicher Zivilisation. Die Verhaltenstugend der Toleranz wird zugleich größer, liberaler und sozialer, je mehr Menschen in großen Städten aufeinander Rücksicht nehmen müssen – Städte sozialisieren. Zugleich mehren sich die Konflikte, die zwar eskalieren, aber auch neue Lebenschancen eröffnen können. In Deutschland werden die politischen Grenzen der Toleranz vor allem im Umgang mit Fremdenfeindlichkeit und Rechtsextremismus diskutiert. Eine Politik des Hasses und der Gewalt gehört nicht mehr zur Toleranz der Demokratie, die ansonsten vieles integrieren und gleichzeitig verändern kann. Urteilsfähige Bürger halten die Demokratie einer breiten und bündnisbereiten politischen Aufklärung, die Grenzen setzen und Orientierung stiften kann, zusammen. Das vorliegende Buch von Heinz Kleger nimmt den Satz „Jeder soll nach seiner Façon selig werden“ als Anstoß zum Nachdenken über die historische Bedeutung des Preußenkönigs, seine damalige Gedankenwelt und politische Theorie. Die Selbstinszenierung Friedrich II. als der "große Kümmerer" und volksnahe König spielen dabei ebenso eine Rolle wie seine Philosophie von Sanssouci und sein Verhältnis zur Aufklärung. Kleger stellt den Satz in den Mittelpunkt unserer heutigen Betrachtungen über Toleranz und das Verhältnis von größtmöglicher individueller Freiheit einerseits und Formen Urbaner (Des)Integration andererseits. Dabei geht es um unser Verhältnis in einer liberalen Demokratie zu Herausforderungen der Zuwanderung und Fragen des politischen Extremismus. Y1 - 2012 SN - 978-3-8448-1577-1 PB - Books on Demand CY - Norderstedt ER - TY - GEN A1 - Hoppe, Sebastian A1 - Bier, Frank Fabian A1 - von Nickisch-Rosenegk, Markus T1 - Microarray-based method for screening of immunogenic proteins from bacteria T2 - Postprints der Universität Potsdam Mathematisch-Naturwissenschaftliche Reihe N2 - Background: Detection of immunogenic proteins remains an important task for life sciences as it nourishes the understanding of pathogenicity, illuminates new potential vaccine candidates and broadens the spectrum of biomarkers applicable in diagnostic tools. Traditionally, immunoscreenings of expression libraries via polyclonal sera on nitrocellulose membranes or screenings of whole proteome lysates in 2-D gel electrophoresis are performed. However, these methods feature some rather inconvenient disadvantages. Screening of expression libraries to expose novel antigens from bacteria often lead to an abundance of false positive signals owing to the high cross reactivity of polyclonal antibodies towards the proteins of the expression host. A method is presented that overcomes many disadvantages of the old procedures. Results: Four proteins that have previously been described as immunogenic have successfully been assessed immunogenic abilities with our method. One protein with no known immunogenic behaviour before suggested potential immunogenicity. We incorporated a fusion tag prior to our genes of interest and attached the expressed fusion proteins covalently on microarrays. This enhances the specific binding of the proteins compared to nitrocellulose. Thus, it helps to reduce the number of false positives significantly. It enables us to screen for immunogenic proteins in a shorter time, with more samples and statistical reliability. We validated our method by employing several known genes from Campylobacter jejuni NCTC 11168. Conclusions: The method presented offers a new approach for screening of bacterial expression libraries to illuminate novel proteins with immunogenic features. It could provide a powerful and attractive alternative to existing methods and help to detect and identify vaccine candidates, biomarkers and potential virulence-associated factors with immunogenic behaviour furthering the knowledge of virulence and pathogenicity of studied bacteria. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 726 KW - expression library KW - immunogenic protein KW - false positive signal KW - polyclonal seron KW - standard western blot Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-429815 SN - 1866-8372 IS - 726 ER - TY - CHAP A1 - Fanselow, Gisbert T1 - Scrambling as formal movement T2 - Contrasts and Positions in Information Structure Y1 - 2012 SN - 978-1-107-00198-5 SP - 267 EP - 295 PB - Cambridge University Press CY - Cambridge ER - TY - GEN A1 - Martins, Fabrice A1 - Bergemann, Maria A1 - Bestenlehner, Joachim M. A1 - Crowther, Paul A. A1 - Hamann, Wolf-Rainer A1 - Najarro, Francisco A1 - Nieva, Maria Fernanda A1 - Przybilla, Norbert A1 - Freimanis, Juris A1 - Hou, Weizhen A1 - Kaper, Lex T1 - SpS5 - II. Stellar and wind parameters T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - The development of infrared observational facilities has revealed a number of massive stars in obscured environments throughout the Milky Way and beyond. The determination of their stellar and wind properties from infrared diagnostics is thus required to take full advantage of the wealth of observations available in the near and mid infrared. However, the task is challenging. This session addressed some of the problems encountered and showed the limitations and successes of infrared studies of massive stars. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 688 KW - infrared: stars KW - stars: early-type KW - stars: late-type KW - stars: fundamental parameters KW - stars: mass loss KW - stars: abundances Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-414956 SN - 1866-8372 IS - 688 ER - TY - GEN A1 - Morris, Penelope J. A1 - Salt, Carina A1 - Raila, Jens A1 - Brenten, Thomas A1 - Kohn, Barbara A1 - Schweigert, Florian J. A1 - Zentek, Jürgen T1 - Safety evaluation of vitamin A in growing dogs T2 - Potsprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - The safe upper limit for inclusion of vitamin A in complete diets for growing dogs is uncertain, with the result that current recommendations range from 5.24 to 104.80 mu mol retinol (5000 to 100 000 IU vitamin A)/4184 kJ (1000 kcal) metabolisable energy (ME). The aim of the present study was to determine the effect of feeding four concentrations of vitamin A to puppies from weaning until 1 year of age. A total of forty-nine puppies, of two breeds, Labrador Retriever and Miniature Schnauzer, were randomly assigned to one of four treatment groups. Following weaning at 8 weeks of age, puppies were fed a complete food supplemented with retinyl acetate diluted in vegetable oil and fed at 1ml oil/100 g diet to achieve an intake of 5.24, 13.10, 78.60 and 104.80 mu mol retinol (5000, 12 500, 75 000 and 100 000 IU vitamin A)/4184 kJ (1000 kcal) ME. Fasted blood and urine samples were collected at 8, 10, 12, 14, 16, 20, 26, 36 and 52 weeks of age and analysed for markers of vitamin A metabolism and markers of safety including haematological and biochemical variables, bone-specific alkaline phosphatase, cross-linked carboxyterminal telopeptides of type I collagen and dual-energy X-ray absorptiometry. Clinical examinations were conducted every 4 weeks. Data were analysed by means of a mixed model analysis with Bonferroni corrections for multiple endpoints. There was no effect of vitamin A concentration on any of the parameters, with the exception of total serum retinyl esters, and no effect of dose on the number, type and duration of adverse events. We therefore propose that 104.80 mu mol retinol (100 000 IU vitamin A)/4184 kJ (1000 kcal) is a suitable safe upper limit for use in the formulation of diets designed for puppy growth. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 686 KW - puppies KW - dogs KW - Retinol KW - Retinyl esters KW - vitamin A Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-414929 IS - 686 ER - TY - JOUR A1 - Winst, Silke T1 - Narration im späten Mittelalter BT - Serialität und Komplexität im Prosaepos ›Loher und Maller‹ JF - Beiträge zur Geschichte der deutschen Sprache und Literatur N2 - In older research literature, the prose epics emerging from the court of Elisabeth of Lorraine and Nassau-Saarbrücken have repeatedly been accused of lacking structure and literariness. By contrast, this article shows that narrative principles of seriality generate the complex structure of the voluminous ›Loher und Maller‹: literary strategies of repetition and variation organize the text on different levels. Recurring narrative structures, thematic constellations and motivations as well as lexical stereotypes are part of this comprehensive principle of seriality. Not triviality and insufficiency, but structural and narrative complexity and lexical accumulation of significance characterize ›Loher und Maller‹. Y1 - 2012 U6 - https://doi.org/10.1515/pbb-2012-0022 SN - 1865-9373 SN - 0005-8076 VL - 134 IS - 2 SP - 220 EP - 238 ER - TY - GEN A1 - Su, Yingna A1 - Kliem, Bernhard A1 - van Ballegooijen, Adriaan A1 - Deluca, Edward T1 - Numerical simulations of the CME on 2010 April 8 T2 - Solar and Astrophysical Dynamos and Magnetic Activity N2 - We present 3D zero-beta ideal MHD simulations of the solar flare/CME event that occurred in Active Region 11060 on 2010 April 8. The initial magnetic configurations of the two simulations are stable nonlinear force-free field and unstable magnetic field models constructed by Su et al. (2011) using the flux rope insertion method. The MHD simulations confirm that the stable model relaxes to a stable equilibrium, while the unstable model erupts as a CME. Comparisons between observations and MHD simulations of the CME are also presented. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 674 KW - Sun: coronal mass ejections (CMEs) KW - Sun: flares KW - Sun: magnetic fields Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-414887 SN - 1866-8372 IS - 674 SP - 575 EP - 576 ER - TY - GEN A1 - Nishikawa, K.-I. A1 - Zhang, B. A1 - Choi, E. J. A1 - Min, K. W. A1 - Niemiec, J. A1 - Medvedev, M. A1 - Hardee, P. A1 - Mizuno, Y. A1 - Nordlund, A. A1 - Frederiksen, J. A1 - Sol, H. A1 - Pohl, Martin A1 - Hartmann, D. H. A1 - Fishman, G.J. T1 - Radiation from accelerated particles in shocks T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - Recent PIC simulations of relativistic electron-positron (electron-ion) jets injected into a stationary medium show that particle acceleration occurs in the shocked regions. Simulations show that the Weibel instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields and for particle acceleration. These magnetic fields contribute to the electron’s transverse eflection behind the shock. The “jitter” radiation from deflected electrons in turbulent magnetic fields has properties different from synchrotron radiation calculated in a uniform magnetic field. This jitter radiation may be important for understanding the complex time evolution and/or spectral structure of gamma-ray bursts, relativistic jets in general, and supernova remnants. In order to calculate radiation from first principles and go beyond the standard synchrotron model, we have used PIC simulations. We present synthetic spectra to compare with the spectra obtained from Fermi observations. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 600 KW - relativistic jets KW - Weibel instability KW - magnetic field generation KW - particle acceleration KW - radiation Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-413128 SN - 1866-8372 IS - 600 SP - 371 EP - 372 ER - TY - GEN A1 - Vink, Jorick Sandor A1 - Heger, Alexander A1 - Krumholz, Mark R. A1 - Puls, Joachim A1 - Banerjee, Shiladitya A1 - Castro, Norberto A1 - Chen, K.-J. A1 - Chenè, A.-N. A1 - Crowther, P. A. A1 - Daminelli, A. A1 - Gräfener, G. A1 - Groh, J. H. A1 - Hamann, Wolf-Rainer A1 - Heap, S. A1 - Herrero, A. A1 - Kaper, L. A1 - Najarro, F. A1 - Oskinova, Lida A1 - Roman-Lopes, A. A1 - Rosen, A. A1 - Sander, A. A1 - Shirazi, M. A1 - Sugawara, Y. A1 - Tramper, F. A1 - Vanbeveren, D. A1 - Voss, R. A1 - Wofford, A. A1 - Zhang, Y. T1 - Very massive stars in the local universe T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Recent studies have claimed the existence of very massive stars (VMS) up to 300 M⊙ in the local Universe. As this finding may represent a paradigm shift for the canonical stellar upper-mass limit of 150 M⊙, it is timely to discuss the status of the data, as well as the far-reaching implications of such objects. We held a Joint Discussion at the General Assembly in Beijing to discuss (i) the determination of the current masses of the most massive stars, (ii) the formation of VMS, (iii) their mass loss, and (iv) their evolution and final fate. The prime aim was to reach broad consensus between observers and theorists on how to identify and quantify the dominant physical processes. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 601 KW - stars: massive stars KW - stars: mass-loss KW - stars: stellar evolution Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-415220 SN - 1866-8372 IS - 601 ER - TY - GEN A1 - Willner, Arne P. A1 - Massonne, Hans-Joachim A1 - Ring, Uwe A1 - Sudo, Masafumi A1 - Thomson, Stuart N. T1 - P–T evolution and timing of a late Palaeozoic fore-arc system and its heterogeneous Mesozoic overprint in north-central Chile (latitudes 31–32° S) T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - In the late Palaeozoic fore-arc system of north-central Chile at latitudes 31-32 degrees S (from the west to the east) three lithotectonic units are telescoped within a short distance by a Mesozoic strikeslip event (derived peak P-T conditions in brackets): (1) the basally accreted Choapa Metamorphic Complex (CMC; 350-430 degrees C, 6-9 kbar), (2) the frontally accreted Arrayan Formation (AF; 280-320 degrees C, 4-6 kbar) and (3) the retrowedge basin of the Huentelauquen Formation (HF; 280-320 degrees C, 3-4 kbar). In the CMC, Ar-Ar spot ages locally date white-mica formation at peak P-T conditions and during early exhumation at 279-242 Ma. In a local garnet mica-schist intercalation (570-585 degrees C, 11-13 kbar) Ar-Ar spot ages refer to the ascent from the subduction channel at 307-274 Ma. Portions of the CMC were isobarically heated to 510-580 degrees C at 6.6-8.5 kbar. The age of peak P-T conditions in the AF can only vaguely be approximated at >= 310 Ma by relict fission-track ages consistent with the observation that frontal accretion occurred prior to basal accretion. Zircon fission-track dating indicates cooling below similar to 280 degrees C at similar to 248 Ma in the CMC and the AF, when a regional unconformity also formed. Ar-Ar white-mica spot ages in parts of the CMC and within the entire AF and HF point to heterogeneous resetting during Mesozoic extensional and shortening events at similar to 245-240 Ma, similar to 210-200 Ma, similar to 174-159 Ma and similar to 142-127 Ma. The zircon fission-track ages are locally reset at 109-96 Ma. All resetting of Ar-Ar white-mica ages is proposed to have occurred by in situ dissolution/precipitation at low temperature in the presence of locally penetrating hydrous fluids. Hence syn-and postaccretionary events in the fore-arc system can still be distinguished and dated in spite of its complex heterogeneous postaccretional overprint. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 597 KW - Ar-Ar white-mica dating KW - zircon fission-track dating KW - accretionary prism KW - frontal accretion KW - basal accretion KW - thermal overprint KW - age resetting Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-414909 SN - 1866-8372 IS - 597 ER - TY - GEN A1 - Radford, Andrew A1 - Felser, Claudia A1 - Boxell, Oliver T1 - Preposition copying and pruning in present-day English T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - This article investigates the nature of preposition copying and preposition pruning structures in present-day English. We begin by illustrating the two phenomena and consider how they might be accounted for in syntactic terms, and go on to explore the possibility that preposition copying and pruning arise for processing reasons. We then report on two acceptability judgement experiments examining the extent to which native speakers of English are sensitive to these types of 'error' in language comprehension. Our results indicate that preposition copying creates redundancy rather than ungrammaticality, whereas preposition pruning creates processing problems for comprehenders that may render it unacceptable in timed (but not necessarily in untimed) judgement tasks. Our findings furthermore illustrate the usefulness of combining corpus studies and experimentally elicited data for gaining a clearer picture of usage and acceptability, and the potential benefits of examining syntactic phenomena from both a theoretical and a processing perspective. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 527 KW - syntactic blends Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-414898 SN - 1866-8364 IS - 527 ER - TY - GEN A1 - Felser, Claudia A1 - Cunnings, Ian A1 - Batterham, Claire A1 - Clahsen, Harald T1 - The timing of island effects in nonnative sentence processing T2 - Postprints der Universität Potsdam Humanwissenschaftliche Reihe N2 - Using the eye-movement monitoring technique in two reading comprehension experiments, this study investigated the timing of constraints on wh-dependencies (so-called island constraints) in first- and second-language (L1 and L2) sentence processing. The results show that both L1 and L2 speakers of English are sensitive to extraction islands during processing, suggesting that memory storage limitations affect L1 and L2 comprehenders in essentially the same way. Furthermore, these results show that the timing of island effects in L1 compared to L2 sentence comprehension is affected differently by the type of cue (semantic fit versus filled gaps) signaling whether dependency formation is possible at a potential gap site. Even though L1 English speakers showed immediate sensitivity to filled gaps but not to lack of semantic fit, proficient German-speaking learners of English as a L2 showed the opposite sensitivity pattern. This indicates that initial wh-dependency formation in L2 processing is based on semantic feature matching rather than being structurally mediated as in L1 comprehension. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 526 KW - trace positions KW - empty categories KW - garden-paths KW - 2nd-language KW - grammar KW - dependencies KW - plausibility KW - constraints KW - english KW - comprehension Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-415179 SN - 1866-8364 EP - 526 ER - TY - GEN A1 - Oskinova, Lida A1 - Guerrero, Martín A. A1 - Hénault-Brunet, Vincent A1 - Sun, W. A1 - Chu, You-Hua A1 - Evans, Chris A1 - Gallagher, John S. A1 - Gruendl, Robert A. A1 - Reyes-Iturbide, Jorge T1 - The slow X-ray pulsar SXP 1062 and associated supernova remnant in the Wing of the Small Magellanic Cloud T2 - Postprints der Universität Potsdam Mathematisch-Naturwissenschaftliche Reihe N2 - SXP 1062 is an exceptional case of a young neutron star in a wind-fed high-mass X-ray binary associated with a supernova remnant. A unique combination of measured spin period, its derivative, luminosity and young age makes this source a key probe for the physics of accretion and neutron star evolution. Theoretical models proposed to explain the properties of SXP 1062 shall be tested with new data. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 591 KW - stars: emission-line KW - Be KW - X-rays: binaries KW - pulsars: individual (SXP 1062) Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-415135 SN - 1866-8372 IS - 591 ER - TY - GEN A1 - Gebser, Martin A1 - Kaufmann, Benjamin A1 - Schaub, Torsten H. T1 - Multi-threaded ASP solving with clasp T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - We present the new multi-threaded version of the state-of-the-art answer set solver clasp. We detail its component and communication architecture and illustrate how they support the principal functionalities of clasp. Also, we provide some insights into the data representation used for different constraint types handled by clasp. All this is accompanied by an extensive experimental analysis of the major features related to multi-threading in clasp. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 586 KW - propositional satisfiability KW - clause elimination KW - parallel execution KW - SAT KW - algorithm KW - platypus KW - systems KW - search KW - solver Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-413977 SN - 1866-8372 IS - 586 ER - TY - GEN A1 - Ostrowski, Max A1 - Schaub, Torsten H. T1 - ASP modulo CSP BT - the clingcon system T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - We present the hybrid ASP solver clingcon, combining the simple modeling language and the high performance Boolean solving capacities of Answer Set Programming (ASP) with techniques for using non-Boolean constraints from the area of Constraint Programming (CP). The new clingcon system features an extended syntax supporting global constraints and optimize statements for constraint variables. The major technical innovation improves the interaction between ASP and CP solver through elaborated learning techniques based on irreducible inconsistent sets. A broad empirical evaluation shows that these techniques yield a performance improvement of an order of magnitude. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 579 KW - answer set KW - constraints KW - logic KW - SMT Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-413908 SN - 1866-8372 IS - 579 ER - TY - GEN A1 - Saki, Adel A1 - Moazzen, Mohssen A1 - Oberhänsli, Roland T1 - Mineral chemistry and thermobarometry of the staurolite-chloritoid schists from Poshtuk, NW Iran T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - The Poshtuk metapelitic rocks in northwestern Iran underwent two main phases of regional and contact metamorphism. Microstructures, textural features and field relations indicate that these rocks underwent a polymetamorphic history. The dominant metamorphic assemblage of the metapelites is garnet, staurolite, chloritoid, chlorite, muscovite and quartz, which grew mainly syntectonically during the later contact metamorphic event. Peak metamorphic conditions of this event took place at 580 ◦ C and ∼ 3–4 kbar, indicating that this event occurred under high-temperature and low-pressure conditions (HT/LP metamorphism), which reflects the high heat flow in this part of the crust. This event is mainly controlled by advective heat input through magmatic intrusions into all levels of the crust. These extensive Eocene metamorphic and magmatic activities can be associated with the early Alpine Orogeny, which resulted in this area from the convergence between the Arabian and Eurasian plates, and the Cenozoic closure of the Tethys oceanic tract(s). T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 578 KW - thermobarometry KW - HT/LP metamorphism KW - Poshtuk metapelites KW - northwestern Iran Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-413942 SN - 1866-8372 IS - 578 SP - 1077 EP - 1088 ER - TY - GEN A1 - Diercke, Andrea A1 - Arlt, Rainer A1 - Denker, Carsten T1 - Digitization of Spörer’s sunspot drawings T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - Much of our knowledge about the solar dynamo is based on sunspot observations. It is thus desirable to extend the set of positional and morphological data of sunspots into the past. Gustav Spörer observed in Germany from Anklam (1861–1873) and Potsdam (1874–1894). He left detailed prints of sunspot groups, which we digitized and processed to mitigate artifacts left in the print by the passage of time. After careful geometrical correction, the sunspot data are now available as synoptic charts for almost 450 solar rotation periods. Individual sunspot positions can thus be precisely determined and spot areas can be accurately measured using morphological image processing techniques. These methods also allow us to determine tilt angles of active regions (Joy’s law) and to assess the complexity of an active region. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 577 KW - sun: sunspots KW - sun: photosphere KW - sun: activity KW - techniques: image processing KW - astronomical databases: miscellaneous KW - history and philosophy of astronomy Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-413922 SN - 1866-8372 IS - 577 SP - 63 EP - 64 ER - TY - GEN A1 - Oskinova, Lida A1 - Feldmeier, Achim A1 - Kretschmar, Peter T1 - Clumped stellar winds in supergiant high-mass X-ray binaries T2 - Postprint der universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - The clumping of massive star winds is an established paradigm, which is confirmed by multiple lines of evidence and is supported by stellar wind theory. We use the results from time-dependent hydrodynamical models of the instability in the line-driven wind of a massive supergiant star to derive the time-dependent accretion rate on to a compact object in the Bondi-Hoyle-Lyttleton approximation. The strong density and velocity fluctuations in the wind result in strong variability of the synthetic X-ray light curves. Photoionization of inhomogeneous winds is different from the photoinization of smooth winds. The degree of ionization is affected by the wind clumping. The wind clumping must also be taken into account when comparing the observed and model spectra of the photoionized stellar wind. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 573 KW - accretion KW - instabilities KW - stars: mass loss KW - X-rays: binaries Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-413916 SN - 1866-8372 IS - 573 SP - 287 EP - 288 ER - TY - GEN A1 - Kirkici, Bilal A1 - Clahsen, Harald T1 - Inflection and derivation in native and non-native language processing BT - masked priming experiments on Turkish T2 - Postprints der Universität Potsdam Humanwissenschaftliche Reihe N2 - Much previous experimental research on morphological processing has focused on surface and meaning-level properties of morphologically complex words, without paying much attention to the morphological differences between inflectional and derivational processes. Realization-based theories of morphology, for example, assume specific morpholexical representations for derived words that distinguish them from the products of inflectional or paradigmatic processes. The present study reports results from a series of masked priming experiments investigating the processing of inflectional and derivational phenomena in native (L1) and non-native (L2) speakers in a non-Indo-European language, Turkish. We specifically compared regular (Aorist) verb inflection with deadjectival nominalization, both of which are highly frequent, productive and transparent in Turkish. The experiments demonstrated different priming patterns for inflection and derivation, specifically within the L2 group. Implications of these findings are discussed both for accounts of L2 morphological processing and for the controversial linguistic distinction between inflection and derivation. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 512 KW - morphological processing KW - second language KW - late bilinguals Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-415664 SN - 1866-8364 IS - 512 ER - TY - GEN A1 - Rothweiler, Monika A1 - Chilla, Solveig A1 - Clahsen, Harald T1 - Subject−verb agreement in Specific Language Impairment BT - a study of monolingual and bilingual German-speaking children T2 - Postprints der Universität Potsdam Humanwissenschaftliche Reihe N2 - This study investigates phenomena that have been claimed to be indicative of Specific Language Impairment (SLI) in German, focusing on subject-verb agreement marking. Longitudinal data from fourteen German-speaking children with SLI, seven monolingual and seven Turkish-German successive bilingual children, were examined. We found similar patterns of impairment in the two participant groups. Both the monolingual and the bilingual children with SLI had correct (present vs. preterit) tense marking and produced syntactically complex sentences such as embedded clauses and wh-questions, but were limited in reliably producing correct agreement-marked verb forms. These contrasts indicate that agreement marking is impaired in German-speaking children with SLI, without any necessary concurrent deficits in either the CP-domain or in tense marking. Our results also show that it is possible to identify SLI from an early successive bilingual child's performance in one of her two languages. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 510 KW - verb morphology KW - tense deficit KW - agreement deficit KW - Turkish−German SLI Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-415122 SN - 1866-8364 IS - 510 ER - TY - GEN A1 - Berger, Frauke A1 - Höhle, Barbara T1 - Restrictions on addition BT - children’s interpretation of the focus particles auch ‘ also ’ and nur ‘ only ’ in German T2 - Postprints der Universität Potsdam Humanwissenschaftliche Reihe N2 - Children up to school age have been reported to perform poorly when interpreting sentences containing restrictive and additive focus particles by treating sentences with a focus particle in the same way as sentences without it. Careful comparisons between results of previous studies indicate that this phenomenon is less pronounced for restrictive than for additive particles. We argue that this asymmetry is an effect of the presuppositional status of the proposition triggered by the additive particle. We tested this in two experiments with German-learning three-and four-year-olds using a method that made the exploitation of the information provided by the particles highly relevant for completing the task. Three-year-olds already performed remarkably well with sentences both with auch 'also' and with nur 'only'. Thus, children can consider the presuppositional contribution of the additive particle in their sentence interpretation and can exploit the restrictive particle as a marker of exhaustivity. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 509 KW - presupposition KW - comprehension KW - implicature KW - acquisition KW - semantics KW - asymmetry KW - tolerance KW - mandarin Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-414911 SN - 1866-8364 IS - 509 ER - TY - BOOK A1 - Krivochen, Diego Gabriel T1 - The Syntax and Semantics of the Nominal Construction BT - A Radically Minimalist Perspective T3 - Potsdam Linguistic Investigations Y1 - 2012 SN - 978-3-631-62448-7 VL - 8 PB - Peter Lang CY - Frankfurt am Main ER - TY - JOUR A1 - Günther, Oliver T1 - More politics in the GI - More GI in politics JF - Informatik-Spektrum Y1 - 2012 U6 - https://doi.org/10.1007/s00287-012-0657-9 VL - 35 IS - 6 SP - 397 EP - 398 ER - TY - CHAP A1 - Schöndienst, Valentin A1 - Kulzer, Florian A1 - Günther, Oliver T1 - Like versus dislike BT - How Facebook's like-button influences people's perception of product and service quality T2 - International Conference on Information Systems : (ICIS 2012) N2 - As Facebook's Like-button has become ubiquitous, it is the purpose of this research to investigate (1) whether Likes serve as a signal of a product's or service's quality and (2) how the introduction of a Dislike-button would alter perceptions. Following a qualitative study, we conducted an experiment in which 653 participants were presented with website screenshots featuring varying levels of Likes and Dislikes. The results indicate that the theoretical framing of Likes as a Signal is valid and that people do perceive the quality of products and services as superior when they are associated with more Likes. Signaling also explains the counter-intuitive finding that Dislikes can have a positive effect on people's quality perceptions. Results are discussed with respect to theory and practical implications. Y1 - 2012 UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84886484949&partnerID=MN8TOARS SP - 439 EP - 454 PB - Curran CY - Red Hook ER - TY - JOUR A1 - Winkler, Till J. A1 - Goebel, Christoph A1 - Bidault, Francis A1 - Günther, Oliver T1 - Information technology and business practieses in Germany BT - results from the 2011 bit survey JF - The UCLA Anderson Business and Information Technologies (BIT) Project Y1 - 2012 U6 - https://doi.org/10.1142/9789814390880_0005 SP - 81 EP - 114 PB - world scientific CY - Singapore ER - TY - CHAP A1 - Günther, Oliver A1 - Winkler, Till J. T1 - Explaining the governance of software as a service applications BT - A process view T2 - Multikonferenz Wirtschaftsinformatik 2012 - Tagungsband der MKWI 2012 N2 - Defining the allocation of decision rights for enterprise applications is a crucial issue in IT governance and organization design. Today, emerging delivery models such as Software as a Service (SaaS) defy the notion of the internal IT department as the focal point of centralized governance. Recognizing the importance of this issue, we find that the phenomenon of 'SaaS governance' itself is not yet well understood. Based on two cases of SaaS adoption, we take a process-theoretic approach to investigate the complex interaction between factors that influence in the allocation of SaaS authority. The results suggest that some factors, such as the locus of initiative and the decision for SaaS, interact with absorptive capacities and determine the later mode of application governance at a very early stage. Thus, the initiative for introducing SaaS emerges as an important intermediate variable between the overall IT governance mode and the resulting SaaS governance outcome. Y1 - 2012 UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84879878424&partnerID=MN8TOARS SN - 978-3-942183-63-5 SP - 599 EP - 612 PB - Gito CY - Berlin ER - TY - JOUR A1 - Günther, Oliver A1 - Brecht, Franziska A1 - Eckhardt, Andreas A1 - Berger, Christian T1 - Corporate career presences on social network sites: an analysis of hedonic and utilitarian value JF - CHI '12 Proceedings of the SIGCHI Conference on Human Factors in Computing Systems N2 - Due to the shortage of skilled workforce and the increasing usage of social network sites, companies increasingly apply social network sites to attract potential applicants. This paper explores how corporate career presences on network sites should be realized in order to attract potential applicants. Therefore, we tested the impact of seven individual characteristics (namely Appointments, Daily Working Routine, Jobs, Corporate News, Entertainment, Media Format, and Features) of these corporate career presences that we extracted by a comprehensive pre-study on users' perceived hedonic and utilitarian value of these presences on social network sites. Based on an online survey with 470 participants, the results reveal a highly significant impact of five characteristics that corporate career presences provide both a hedonic as well as a utilitarian value to the user Y1 - 2012 SN - 978-1-4503-1015-4 U6 - https://doi.org/10.1145/2207676.2208408 SP - 2441 EP - 2450 PB - ACM CY - Texas ER - TY - GEN A1 - Festman, Julia T1 - Language control abilities of late bilinguals T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - Although all bilinguals encounter cross-language interference (CLI), some bilinguals are more susceptible to interference than others. Here, we report on language performance of late bilinguals (Russian/German) on two bilingual tasks (interview, verbal fluency), their language use and switching habits. The only between-group difference was CLI: one group consistently produced significantly more errors of CLI on both tasks than the other (thereby replicating our findings from a bilingual picture naming task). This striking group difference in language control ability can only be explained by differences in cognitive control, not in language proficiency or language mode. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 459 KW - language control KW - language proficiency KW - interference KW - error analysis KW - language mode KW - switching attitude Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-413930 IS - 459 ER - TY - JOUR A1 - Stadler, Heike T1 - Sich der Diskussion stellen BT - eine Online-Petition sorgt schnell für Aufsehen : erfolgreiche Beispiele JF - BuB : Forum für Bibliothek und Information 64 (2012) 4 N2 - Die Zukunftswerkstatt wollte wissen, ob Konzepte wie Liquid Democracy (http://liqd.net/) und Plattformen wie Adhocracy (http://code.adhocracy.de/) oder AVAAZ (www.avaaz.org/ de/) konkret für das Bibliothekswesen eingesetzt werden können. Die Beteiligung an der Internet-Enquete Kommission des Bundestages (https://enquetebeteiligung. de/) zeigte, dass die Nutzung im Sinne von gemeinschaftlicher Politikberatung möglich ist. Die »Stop SOPA/PIPA«- und die »Anti-ACTA«-Mobilisierungen belegen, dass Politik immer mehr auf die Bürger eingehen muss – und Social Media mitnichten tot sind. Heike Stadler beschäftigt sich intensiv mit dem Thema »Bürgerbeteiligungen für Bibliotheken« (siehe unter anderem BuB Heft 6/2011, Seite 450). Hier ihr Beitrag für die Zukunftswerkstatt Y1 - 2012 UR - www.b-u-b.de/pdfarchiv/Heft-BuB_04_2012.pdf VL - 64 IS - 4 SP - 248 PB - Bock + Herchen CY - Bad Honnef ER - TY - GEN A1 - Salzwedel, Annett A1 - Nosper, Manfred A1 - Röhrig, Bernd A1 - Linck-Eleftheriadis, Sigrid A1 - Strandt, Gert A1 - Völler, Heinz T1 - Outcome quality of in-patient cardiac rehabilitation in elderly patients – identification of relevant parameters T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - Background Outcome quality management requires the consecutive registration of defined variables. The aim was to identify relevant parameters in order to objectively assess the in-patient rehabilitation outcome. Methods From February 2009 to June 2010 1253 patients (70.9 ± 7.0 years, 78.1% men) at 12 rehabilitation clinics were enrolled. Items concerning sociodemographic data, the impairment group (surgery, conservative/interventional treatment), cardiovascular risk factors, structural and functional parameters and subjective health were tested in respect of their measurability, sensitivity to change and their propensity to be influenced by rehabilitation. Results The majority of patients (61.1%) were referred for rehabilitation after cardiac surgery, 38.9% after conservative or interventional treatment for an acute coronary syndrome. Functionally relevant comorbidities were seen in 49.2% (diabetes mellitus, stroke, peripheral artery disease, chronic obstructive lung disease). In three key areas 13 parameters were identified as being sensitive to change and subject to modification by rehabilitation: cardiovascular risk factors (blood pressure, low-density lipoprotein cholesterol, triglycerides), exercise capacity (resting heart rate, maximal exercise capacity, maximal walking distance, heart failure, angina pectoris) and subjective health (IRES-24 (indicators of rehabilitation status): pain, somatic health, psychological well-being and depression as well as anxiety on the Hospital Anxiety and Depression Scale). Conclusion The outcome of in-patient rehabilitation in elderly patients can be comprehensively assessed by the identification of appropriate key areas, that is, cardiovascular risk factors, exercise capacity and subjective health. This may well serve as a benchmark for internal and external quality management. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 390 KW - cardiac rehabilitation KW - quality management KW - outcome measures Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-404151 IS - 390 ER - TY - GEN A1 - Wattendorf, Elise A1 - Festman, Julia A1 - Westermann, Birgit A1 - Keil, Ursula A1 - Zappatore, Daniela A1 - Franceschini, Rita A1 - Luedi, Georges A1 - Radue, Ernst-Wilhelm A1 - Münte, Thomas F. A1 - Rager, Günter A1 - Nitsch, Cordula T1 - Early bilingualism influences early and subsequently later acquired languages in cortical regions representing control functions T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - Early acquisition of a second language influences the development of language abilities and cognitive functions. In the present study, we used functional Magnetic Resonance Imaging (fMRI) to investigate the impact of early bilingualism on the organization of the cortical language network during sentence production. Two groups of adult multilinguals, proficient in three languages, were tested on a narrative task; early multilinguals acquired the second language before the age of three years, late multilinguals after the age of nine. All participants learned a third language after nine years of age. Comparison of the two groups revealed substantial differences in language-related brain activity for early as well as late acquired languages. Most importantly, early multilinguals preferentially activated a fronto-striatal network in the left hemisphere, whereas the left posterior superior temporal gyrus (pSTG) was activated to a lesser degree than in late multilinguals. The same brain regions were highlighted in previous studies when a non-target language had to be controlled. Hence the engagement of language control in adult early multilinguals appears to be influenced by the specific learning and acquisition conditions during early childhood. Remarkably, our results reveal that the functional control of early and subsequently later acquired languages is similarly affected, suggesting that language experience has a pervasive influence into adulthood. As such, our findings extend the current understanding of control functions in multilinguals. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 384 KW - multilingual KW - language acquisition KW - narration KW - age of acquisition KW - functional magnetic resonance imaging KW - emergentist framework Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-404092 IS - 384 ER - TY - GEN A1 - Ganghof, Steffen T1 - Does public reason require super-majoritarian democracy? BT - Liberty, equality, and history in the justification of political institutions T2 - Politics, philosophy & economics N2 - The project of public-reason liberalism faces a basic problem: publicly justified principles are typically too abstract and vague to be directly applied to practical political disputes, whereas applicable specifications of these principles are not uniquely publicly justified. One solution could be a legislative procedure that selects one member from the eligible set of inconclusively justified proposals. Yet if liberal principles are too vague to select sufficiently specific legislative proposals, can they, nevertheless, select specific legislative procedures? Based on the work of Gerald Gaus, this article argues that the only candidate for a conclusively justified decision procedure is a majoritarian or otherwise ‘neutral’ democracy. If the justification of democracy requires an equality baseline in the design of political regimes and if justifications for departure from this baseline are subject to reasonable disagreement, a majoritarian design is justified by default. Gaus’s own preference for super-majoritarian procedures is based on disputable specifications of justified liberal principles. These procedures can only be defended as a sectarian preference if the equality baseline is rejected, but then it is not clear how the set of justifiable political regimes can be restricted to full democracies. T3 - Zweitveröffentlichungen der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe - 86 KW - public-reason liberalism KW - democracy KW - coercion KW - political equality KW - majority rule KW - Gerald Gaus Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-477860 VL - 12 IS - 2 ER - TY - THES A1 - Richter, Johanna T1 - Transformationen des Romans im Zeitalter der Presse BT - Paris und London: 1836-1881 Y1 - 2012 ER - TY - JOUR A1 - Röttgen, Norbert ED - Kleinwächter, Kai T1 - Regierungserklärung zu den Ergebnissen der Klimakonferenz in Durban BT - Bundesminister für Umwelt, Naturschutz und Reaktorsicherheit, Dr. Norbert Röttgen, am 16. Dezember 2011 (Auszüge) JF - Klimapolitik International KW - Klimapolitik KW - Klima KW - Durban 2011 KW - Klimakonferenz KW - NGO KW - Entwicklungspolitik KW - climate policy KW - climate KW - Climate Change Conference KW - development policy Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-81376 SN - 1868-6222 SN - 1868-6230 SP - 93 EP - 100 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Balderjahn, Ingo A1 - Peyer, Mathias T1 - Das Bewusstsein für fairen Konsum : Konzeptualisierung, Messung und Wirkung JF - Die Betriebswirtschaft : DBW N2 - Die vorliegende Arbeit fokussiert auf den fairen Konsum als Teil des ethischen Konsums. Unter fairem Konsum verstehen wir Kaufentscheidungen, die unter Berücksichtigung der Einhaltung fairer Arbeits- und Geschäftsbedingungen bei der Herstellung von Produkten erfolgen. Unter Einsatz einer neu entwickelten Skala zur Messung des fairen Konsumbewusstseins können wir empirisch nachweisen, dass Produkte mit einem Fairtrade-Siegel Konsumenten einen moralischen Zusatznutzen vermitteln können, für den sie bereit sind, einen Mehrpreis zu zahlen. N2 - The present paper focuses on fair consumption, as a part of ethical consumerism. Fair consumption means purchasing decisions made in the light of compliance with fair labor and business conditions in the manufacturing process. Using a new developed scale for the measurement of the consciousness for fair consumption, we can prove empirically that fair trade products can provide an additional moral value for consumers for which they are willingly to pay an extra charge. T2 - The consciousness for fair consumption : conceptualization, measuring, and impacts KW - Conjoint Analyse KW - Consumer Social Responsibility KW - ethischer Konsum KW - faires Konsumbewusstsein KW - Fairtrade KW - Strukturgleichungsmodelle KW - Zahlungsbereitschaft KW - Conjoint analysis KW - consciousness for fair consumption KW - consumer social responsibility KW - ethical consumerism KW - fairtrade KW - structural equation modeling KW - willingness-to-pay Y1 - 2012 SN - 0342-7064 VL - 72 IS - 4 SP - 343 EP - 364 PB - Schäffer-Poeschel CY - Stuttgart ER - TY - CHAP A1 - Balderjahn, Ingo A1 - Peyer, Mathias ED - Corsten, Hans ED - Roth, Stefan T1 - Soziales Konsumbewusstsein: Skalenentwicklung und –validierung T2 - Nachhaltigkeit – Unternehmerisches Handeln in globaler Verantwortung Y1 - 2012 SN - 978-3-8349-3179-5 SP - 93 EP - 112 PB - Springer Gabler CY - Wiesbaden ER - TY - JOUR A1 - Weiß, Norman ED - Breuer, Marten ED - Epinay, Astrid ED - Haratsch, Andreas ED - Schmahl, Stefanie ED - Weiß, Norman T1 - Der Rechtsstaat im Risiko JF - Der Staat im Recht : Festschrift für Eckart Klein zum 70. Geburtstag (Schriften zum öffentlichen Recht ; Bd. 1232) Y1 - 2012 SN - 978-3-428-13738-1 SP - 365 EP - 383 PB - Duncker & Humblot CY - Berlin ER - TY - JOUR A1 - Weiß, Norman T1 - Bedeutung und Funktion von Zivilgesellschaft und Öffentlichkeit im demokratischen Rechtsstaat am Beispiel der Bundesrepublik Deutschland JF - Jahrbuch des Öffentlichen Rechts der Gegenwart : Neue Folge ; 61 Y1 - 2012 UR - https://www.mohrsiebeck.com/buch/jahrbuch-des-oeffentlichen-rechts-der-gegenwart-neue-folge-9783161524172 SN - 978-3-16-152417-2 SN - 0075-2517 VL - 61 SP - 15 EP - 60 PB - Mohr Siebeck CY - Tübingen ER - TY - JOUR A1 - Pimpalpalle, Tukaram M. A1 - Yin, Jian A1 - Linker, Torsten T1 - Barton radical reactions of 2-C-branched carbohydrates JF - Organic & biomolecular chemistry : an international journal of synthetic, physical and biomolecular organic chemistry N2 - Barton esters have been introduced into the side chain of carbohydrates with high yields in only a few steps from easily available glycals. Their radical reactions afford 2-C-methyl and 2-C-bromomethyl hexoses, pentoses and disaccharides in good yields in analytically pure form. Since the Barton esters have been synthesized by an oxidative radical addition and their transformations by reductive radical processes, our results demonstrate the power of such reactions in carbohydrate chemistry. Y1 - 2012 U6 - https://doi.org/10.1039/c1ob06370g SN - 1477-0520 VL - 10 IS - 1 SP - 103 EP - 109 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Wang, Yongbo A1 - Liu, Xingqi A1 - Mischke, Steffen A1 - Herzschuh, Ulrike T1 - Environmental constraints on lake sediment mineral compositions from the Tibetan Plateau and implications for paleoenvironment reconstruction JF - Journal of paleolimnolog N2 - Inorganic minerals form a major component of lacustrine sediments and have the potential to reveal detailed information on previous climatic and hydrological conditions. The ability to extract such information however, has been restricted by a limited understanding of the relationships between minerals and the environment. In an attempt to fill in this gap in our knowledge, 146 surface sediment samples have been investigated from 146 lakes on the Tibetan Plateau. The mineral compositions derived from these samples by X-Ray Diffraction (XRD) were used to examine the relationships between mineral compositions and the environmental variables determined for each site. Statistical techniques including Multivariate regression trees (MRT) and Redundancy Analysis (RDA), based on the mineral spectra and environmental variables, reveal that the electrical conductivity (EC) and Mg/Ca ratios of lake water are the most important controls on the composition of endogenic minerals. No endogenic minerals precipitate under hyper-fresh water conditions (EC lower than 0.13 mS/cm), with calcite commonly forming in water with EC values above 0.13 mS/cm. Between EC values of 0.13 and 26 mS/cm the mineral composition of lake sediments can be explained in terms of variations in the Mg/Ca ratio: calcite dominates at Mg/Ca ratios of less than 33, whereas aragonite commonly forms when the ratio is greater than 33. Where EC values are between 26 and 39 mS/cm, monohydrocalcite precipitates together with calcite and aragonite; above 39 mS/cm, gypsum and halite commonly form. Information on the local geological strata indicates that allogenic (detrital) mineral compositions are primarily influenced by the bedrock compositions within the catchment area. By applying these relationships to the late glacial and Holocene mineral record from Chaka Salt Lake, five lake stages have been identified and their associated EC conditions inferred. The lake evolved from a freshwater lake during the late glacial (before 11.4 cal. ka BP) represented by the lowest EC values (< 0.13 mS/cm), to a saline lake with EC values slightly higher than 39 mS/cm during the early and mid Holocene (ca. 11.4-5.3 cal. ka BP), and finally to a salt lake (after 5.3 cal. ka BP). These results illustrate the utility of our mineral-environmental model for the quantitative reconstruction of past environmental conditions from lake sediment records. KW - Mineral composition KW - XRD KW - Multivariate regression trees KW - Electrical conductivity KW - Paleolimnology KW - Tibetan Plateau Y1 - 2012 U6 - https://doi.org/10.1007/s10933-011-9549-2 SN - 0921-2728 VL - 47 IS - 1 SP - 71 EP - 85 PB - Springer CY - Dordrecht ER - TY - CHAP A1 - Ohl, Sven A1 - Brandt, S. A1 - Kliegl, Reinhold T1 - Post-saccadic location judgments after presentation of multiple target-like objects T2 - Perception Y1 - 2012 SN - 0301-0066 SN - 1468-4233 VL - 41 IS - 1 SP - 171 EP - 171 PB - Sage Publ. CY - London ER - TY - CHAP A1 - Laubrock, Jochen A1 - Cajar, Anke A1 - Engbert, Ralf T1 - Peripheral spatial frequency processing affects timing and metrics of saccades T2 - Perception Y1 - 2012 SN - 0301-0066 SN - 1468-4233 VL - 41 SP - 170 EP - 170 PB - Sage Publ. CY - London ER - TY - CHAP A1 - Krügel, Andre A1 - Engbert, Ralf T1 - Saccade targeting of spatially extended objects a Bayesian model T2 - Perception Y1 - 2012 SN - 0301-0066 SN - 1468-4233 VL - 41 SP - 167 EP - 167 PB - Sage Publ. CY - London ER - TY - CHAP A1 - Risse, Sarah T1 - Letter crowding and the benefit of parafoveal preview during reading T2 - Perception Y1 - 2012 SN - 0301-0066 SN - 1468-4233 VL - 41 SP - 133 EP - 133 PB - Sage Publ. CY - London ER - TY - CHAP A1 - Trukenbrod, Hans Arne A1 - Barthelme, S. A1 - Wichmann, Felix A. A1 - Engbert, Ralf T1 - Color does not guide eye movements: Evidence from a gaze-contingent experiment T2 - PERCEPTION Y1 - 2012 SN - 0301-0066 SN - 1468-4233 VL - 41 SP - 88 EP - 88 PB - PION LTD CY - LONDON ER - TY - CHAP A1 - Engbert, Ralf T1 - A computational model of microsaccadic responses to shifts of covert attention T2 - Perception Y1 - 2012 SN - 0301-0066 SN - 1468-4233 VL - 41 SP - 55 EP - 55 PB - Sage Publ. CY - London ER - TY - JOUR A1 - Hildebrandt, Niko A1 - Geissler, Daniel ED - Zahavy, E ED - Ordentlich, A ED - Yitzhaki, S ED - Shafferman, A T1 - Semiconductor quantum dots as FRET acceptors for multiplexed diagnostics and molecular ruler application JF - Advances in Experimental Medicine and Biology N2 - Applications based on Forster resonance energy transfer (FRET) play an important role for the determination of concentrations and distances within nanometer-scale systems in vitro and in vivo in many fields of biotechnology. Semiconductor nanocrystals (Quantum dots - QDs) possess ideal properties for their application as FRET acceptors when the donors have long excited state lifetimes and when direct excitation of QDs can be efficiently suppressed. Therefore, luminescent terbium complexes (LTCs) with excited state lifetimes of more than 2 ms are ideal FRET donor candidates for QD-acceptors. This chapter will give a short overview of theoretical and practical background of FRET, QDs and LTCs, and present some recent applications of LTC-QD FRET pairs for multiplexed ultra-sensitive in vitro diagnostics and nanometer-resolution molecular distance measurements. KW - Diagnostics KW - FRET KW - Imaging KW - Quantum dots KW - Terbium Y1 - 2012 SN - 978-94-007-2554-6 SN - 978-94-007-2555-3 U6 - https://doi.org/10.1007/978-94-007-2555-3_8 SN - 0065-2598 VL - 733 SP - 75 EP - 86 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Wellmann, Caroline A1 - Holzgrefe-Lang, Julia A1 - Truckenbrodt, Hubert A1 - Wartenburger, Isabell A1 - Höhle, Barbara T1 - How each prosodic boundary cue matters evidence from German infants JF - Frontiers in psychology N2 - Previous studies have revealed that infants aged 6-10 months are able to use the acoustic correlates of major prosodic boundaries, that is, pitch change, preboundary lengthening, and pause, for the segmentation of the continuous speech signal. Moreover, investigations with American-English- and Dutch-learning infants suggest that processing prosodic boundary markings involves a weighting of these cues. This weighting seems to develop with increasing exposure to the native language and to underlie crosslinguistic variation. In the following, we report the results of four experiments using the headturn preference procedure to explore the perception of prosodic boundary cues in German infants. We presented 8-month-old infants with a sequence of names in two different prosodic groupings, with or without boundary markers. Infants discriminated both sequences when the boundary was marked by all three cues (Experiment 1) and when it was marked by a pitch change and preboundary lengthening in combination (Experiment 2). The presence of a pitch change (Experiment 3) or preboundary lengthening (Experiment 4) as single cues did not lead to a successful discrimination. Our results indicate that pause is not a necessary cue for German infants. Pitch change and preboundary lengthening in combination, but not as single cues, are sufficient. Hence, by 8 months infants only rely on a convergence of boundary markers. Comparisons with adults' performance on the same stimulus materials suggest that the pattern observed with the 8-month-olds is already consistent with that of adults. We discuss our findings with respect to crosslinguistic variation and the development of a language-specific prosodic cue weighting. KW - infants KW - language acquisition KW - speech perception KW - prosodic bootstrapping KW - prosodic boundary cues KW - cue weighting KW - intonation phrase boundary KW - headturn preference procedure Y1 - 2012 U6 - https://doi.org/10.3389/fpsyg.2012.00580 SN - 1664-1078 VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Henrichs, Ivanina A1 - Elsner, Claudia A1 - Elsner, Birgit A1 - Gredeback, Gustaf T1 - Goal salience affects infants' goal-directed gaze shifts JF - Frontiers in psychology N2 - Around their first year of life, infants are able to anticipate the goal of others' ongoing actions. For instance, 12-month-olds anticipate the goal of everyday feeding actions and manual actions such as reaching and grasping. However, little is known whether the salience of the goal influences infants' online assessment of others' actions. The aim of the current eye-tracking study was to elucidate infants' ability to anticipate reaching actions depending on the visual salience of the goal object. In Experiment 1, 12-month-old infants' goal-directed gaze shifts were recorded as they observed a hand reaching for and grasping either a large (high-salience condition) or a small (low-salience condition) goal object. Infants exhibited predictive gaze shifts significantly earlier when the observed hand reached for the large goal object compared to when it reached for the small goal object. In addition, findings revealed rapid learning over the course of trials in the high-salience condition and no learning in the low-salience condition. Experiment 2 demonstrated that the results could not be simply attributed to the different grip aperture of the hand used when reaching for small and large objects. Together, our data indicate that by the end of their first year of life, infants rely on information about the goal salience to make inferences about the action goal. KW - anticipation KW - eye movement KW - salience KW - infant KW - action understanding Y1 - 2012 U6 - https://doi.org/10.3389/fpsyg.2012.00391 SN - 1664-1078 VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - INPR A1 - Fischer, Martin H. A1 - Kaufmann, Liane A1 - Domahs, Frank T1 - Finger counting and numerical cognition T2 - Frontiers in psychology Y1 - 2012 U6 - https://doi.org/10.3389/fpsyg.2012.00108 SN - 1664-1078 VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Festman, Julia A1 - Muente, Thomas F. T1 - Cognitive control in Russian-German bilinguals JF - Frontiers in psychology N2 - Bilingual speakers are faced with the problem to keep their languages apart, but do so with interindividually varying success. Cognitive control abilities might be an important factor to explain such interindividual differences. Here we compare two late, balanced and highly proficient bilingual groups (mean age 24 years, L1 Russian, L2 German) which were established according to their language control abilities on a bilingual picture-naming task. One group had difficulties to remain in the instructed target language and switched unintentionally to the non-target language ("switchers"), whereas the other group rarely switched unintentionally ("non-switchers"). This group-specific behavior could not be explained by language background, socio-cultural, or demographic variables. Rather, the non-switchers also demonstrated a faster and better performance on four cognitive control tests (Tower of Hanoi, Ruff Figural Fluency Test, Divided Attention, Go/Nogo). Here, we focus on two additional executive function tasks, theWisconsin Card SortingTest (WCST) and the Flanker task requiring conflict monitoring and conflict resolution. Non-switchers outperformed switchers with regard to speed and accuracy, and were better at finding and applying the correct rules in the WCST. Similarly, in the Flanker task non-switchers performed faster and better on conflict trials and had a higher correction rate following an error. Event-related potential recordings furthermore revealed a smaller error-related negativity in the non-switchers, taken as evidence for a more efficient self-monitoring system. We conclude that bilingual language performance, in particular switching behavior, is related to performance on cognitive control tasks. Better cognitive control, including conflict monitoring, results in decreased unintentional switching. KW - Flanker task KW - ERN KW - Wisconsin Card Sorting Test KW - conflict monitoring KW - inhibition KW - late bilinguals KW - cognitive control KW - executive function Y1 - 2012 U6 - https://doi.org/10.3389/fpsyg.2012.00115 SN - 1664-1078 VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Domahs, Ulrike A1 - Knaus, Johannes A1 - Orzechowska, Paula A1 - Wiese, Richard T1 - Stress "deafness" in a language with fixed word stress an ERR study on Polish JF - Frontiers in psychology N2 - The aim of the present contribution was to examine the factors influencing the prosodic processing in a language with predictable word stress. For Polish, a language with fixed penultimate stress but several well-defined exceptions, difficulties in the processing and representation of prosodic information have been reported (e.g., Peperkamp and Dupoux, 2002). The present study utilized event-related potentials (ERPs) to investigate the factors influencing prosodic processing in Polish. These factors are (i) the predictability of stress and (ii) the prosodic structure in terms of metrical feet. Polish native speakers were presented with correctly and incorrectly stressed Polish words and instructed to judge the correctness of the perceived stress patterns. For some stress violations, an early negativity was found which was interpreted as a reflection of an error-detection mechanism. In addition, exceptional stress patterns (=antepenultimate stress) and post-lexical (=initial) stress evoked a task-related positivity effect (P300) whose amplitude and latency is correlated with the degree of anomaly and deviation from an expectation. In contrast, violations involving the default (=penultimate stress) did not produce such an effect. This asymmetrical result is interpreted to reflect that Polish native speakers are less sensitive to the default pattern than to the exceptional or post-lexical patterns. Behavioral results are orthogonal to the electrophysiological results showing that Polish speakers had difficulties to reject any kind of stress violation. Thus, on a meta-linguistic level Polish speakers appeared to be stress-"deaf" for any kind of stress manipulation, whereas the neural reactions differentiate between the default and lexicalized patterns. KW - stress "deafness" KW - fixed stress system KW - prosodic representation KW - P300 KW - generalized error-detection mechanism Y1 - 2012 U6 - https://doi.org/10.3389/fpsyg.2012.00439 SN - 1664-1078 VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Rocchetti, Alessandra A1 - Sharma, Tripti A1 - Wulfetange, Camilla A1 - Scholz-Starke, Joachim A1 - Grippa, Alexandra A1 - Carpaneto, Armando A1 - Dreyer, Ingo A1 - Vitale, Alessandro A1 - Czempinski, Katrin A1 - Pedrazzini, Emanuela T1 - The putative K+ channel subunit AtKCO3 forms stable dimers in arabidopsis JF - Frontiers in plant science N2 - The permeation pore of K+ channels is formed by four copies of the pore domain. AtKCO3 is the only putative voltage-independent K+ channel subunit of Arabidopsis thaliana with a single pore domain. KCO3-like proteins recently emerged in evolution and, to date, have been found only in the genus Arabidopsis (A. thaliana and A. lyrata). We show that the absence of KCO3 does not cause marked changes in growth under various conditions. Only under osmotic stress we observed reduced root growth of the kco3-1 null-allele line. This phenotype was complemented by expressing a KCO3 mutant with an inactive pore, indicating that the function of KCO3 under osmotic stress does not depend on its direct ability to transport ions. Constitutively overexpressed AtKCO3 or AtKCO3::G FP are efficiently sorted to the tonoplast indicating that the protein is approved by the endoplasmic reticulum quality control. However, vacuoles isolated from transgenic plants do not have significant alterations in current density. Consistently, both AtKCO3 and AtKCO3::GFP are detected as homodimers upon velocity gradient centrifugation, an assembly state that would not allow for activity. We conclude that if AtKCO3 ever functions as a K+ channel, active tetramers are held by particularly weak interactions, are formed only in unknown specific conditions and may require partner proteins. KW - Arabidopsis KW - membrane proteins KW - potassium channels KW - protein assembly KW - tonoplast Y1 - 2012 U6 - https://doi.org/10.3389/fpls.2012.00251 SN - 1664-462X VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Lucia Gomez-Porras, Judith A1 - Mauricio Riano-Pachon, Diego A1 - Benito, Begona A1 - Haro, Rosario A1 - Sklodowski, Kamil A1 - Rodriguez-Navarro, Alonso A1 - Dreyer, Ingo T1 - Phylogenetic analysis of K+ transporters in bryophytes, lycophytes, and flowering plants indicates a specialization of vascular plants JF - Frontiers in plant science N2 - As heritage from early evolution, potassium (K+) is absolutely necessary for all living cells. It plays significant roles as stabilizer in metabolism and is important for enzyme activation, stabilization of protein synthesis, and neutralization of negative charges on cellular molecules as proteins and nucleic acids. Land plants even enlarged this spectrum of K+ utilization after having gone ashore, despite the fact that K+ is far less available in their new oligotrophic habitats than in sea water. Inevitably, plant cells had to improve and to develop unique transport systems for K+ accumulation and distribution. In the past two decades a manifold of K+ transporters from flowering plants has been identified at the molecular level. The recently published genome of the fern ally Selaginella moellendorffii now helps in providing a better understanding on the molecular changes involved in the colonization of land and the development of the vasculature and the seeds. In this article we present an inventory of K+ transporters of this lycophyte and pigeonhole them together with their relatives from the moss Physcomitrella patens, the monocotyledon Oryza sativa, and two dicotyledonous species, the herbaceous plant Arabidopsis thaliana, and the tree Populus trichocarpa. Interestingly, the transition of green plants from an aqueous to a dry environment coincides with a dramatic reduction in the diversity of voltage-gated potassium channels followed by a diversification on the basis of one surviving K+ channel class. The first appearance of K+ release (K-out) channels in S. moellendorffii that were shown in Arabidopsis to be involved in xylem loading and guard cell closure coincides with the specialization of vascular plants and may indicate an important adaptive step. KW - potassium KW - transport KW - channel KW - voltage-dependent KW - voltage-independent KW - high-affinity KW - Selaginella Y1 - 2012 U6 - https://doi.org/10.3389/fpls.2012.00167 SN - 1664-462X VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Christian, Jan-Ole A1 - Braginets, Rostyslav A1 - Schulze, Waltraud X. A1 - Walther, Dirk T1 - Characterization and prediction of protein phosphorylation hotspots in Arabidopsis thaliana JF - Frontiers in plant science N2 - The regulation of protein function by modulating the surface charge status via sequence-locally enriched phosphorylation sites (P-sites) in so called phosphorylation "hotspots" has gained increased attention in recent years. We set out to identify P-hotspots in the model plant Arabidopsis thaliana. We analyzed the spacing of experimentally detected P-sites within peptide-covered regions along Arabidopsis protein sequences as available from the PhosPhAt database. Confirming earlier reports (Schweiger and Lanial, 2010), we found that, indeed, P-sites tend to cluster and that distributions between serine and threonine P-sites to their respected closest next P-site differ significantly from those for tyrosine P-sites. The ability to predict P-hotspots by applying available computational P-site prediction programs that focus on identifying single P-sites was observed to be severely compromised by the inevitable interference of nearby P-sites. We devised a new approach, named HotSPotter, for the prediction of phosphorylation hotspots. HotSPotter is based primarily on local amino acid compositional preferences rather than sequence position-specific motifs and uses support vector machines as the underlying classification engine. HotSPotter correctly identified experimentally determined phosphorylation hotspots in A. thaliana with high accuracy. Applied to the Arabidopsis proteome, HotSPotter-predicted 13,677 candidate P-hotspots in 9,599 proteins corresponding to 7,847 unique genes. Hotspot containing proteins are involved predominantly in signaling processes confirming the surmised modulating role of hotspots in signaling and interaction events. Our study provides new bioinformatics means to identify phosphorylation hotspots and lays the basis for further investigating novel candidate P-hotspots. All phosphorylation hotspot annotations and predictions have been made available as part of the PhosPhAt database at http://phosphat.mpimp-golm.mpg.de. KW - protein phosphorylation KW - hotspots KW - Arabidopsis thaliana KW - support vector machines KW - regulation Y1 - 2012 U6 - https://doi.org/10.3389/fpls.2012.00207 SN - 1664-462X VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Balazadeh, Salma A1 - Jaspert, Nils A1 - Arif, Muhammad A1 - Müller-Röber, Bernd A1 - Maurino, Veronica G. T1 - Expression of ROS-responsive genes and transcription factors after metabolic formation of H2O2 in chloroplasts JF - Frontiers in plant science N2 - Glycolate oxidase (GO) catalyses the oxidation of glycolate to glyoxylate, thereby consuming O-2 and producing H2O2. In this work, Arabidopsis thaliana plants expressing GO in the chloroplasts (GO plants) were used to assess the expressional behavior of reactive oxygen species (ROS)-responsive genes and transcription factors (TFs) after metabolic induction of H2O2 formation in chloroplasts. In this organelle, GO uses the glycolate derived from the oxygenase activity of RubisCO. Here, to identify genes responding to an abrupt production of H2O2 in chloroplasts we used quantitative real-time PCR (qRT-PCR) to test the expression of 187 ROS-responsive genes and 1880 TFs after transferring GO and wild-type (WT) plants grown at high CO2 levels to ambient CO2 concentration. Our data revealed coordinated expression changes of genes of specific functional networks 0.5 h after metabolic induction of H2O2 production in GO plants, including the induction of indole glucosinolate and camalexin biosynthesis genes. Comparative analysis using available microarray data suggests that signals for the induction of these genes through H2O2 may originate in the chloroplast. The TF profiling indicated an up-regulation in GO plants of a group of genes involved in the regulation of proanthocyanidin and anthocyanin biosynthesis. Moreover, the upregulation of expression of IF and IF interacting proteins affecting development (e.g., cell division, stem branching, flowering time, flower development) would impact growth and reproductive capacity, resulting in altered development under conditions that promote the formation of H2O2. KW - glycolate oxidase KW - H2O2 KW - ROS-responsive genes KW - transcription factors Y1 - 2012 U6 - https://doi.org/10.3389/fpls.2012.00234 SN - 1664-462X VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Spijkerman, Elly A1 - Wacker, Alexander A1 - Weithoff, Guntram A1 - Leya, Thomas T1 - Elemental and fatty acid composition of snow algae in Arctic habitats JF - Frontiers in microbiology N2 - Red, orange or green snow is the macroscopic phenomenon comprising different eukaryotic algae. Little is known about the ecology and nutrient regimes in these algal communities. Therefore, eight snow algal communities from five intensively tinted snow fields in western Spitsbergen were analysed for nutrient concentrations and fatty acid (FA) composition. To evaluate the importance of a shift from green to red forms on the FA-variability of the field samples, four snow algal strains were grown under nitrogen replete and moderate light (+N+ML) or N-limited and high light (-N+HL) conditions. All eight field algal communities were dominated by red and orange cysts. Dissolved nutrient concentration of the snow revealed a broad range of NH4+ (<0.005-1.2 mg NI-1) and only low PO43- (< 18 mu g P I-1) levels. The external nutrient concentration did not reflect cellular nutrient ratios as C:N and C:P ratios of the communities were highest at locations containing relatively high concentrations of NH4- and PO43-. Molar N:P ratios ranged from 11 to 21 and did not suggest clear limitation of a single nutrient. On a per carbon basis, we found a 6-fold difference in total FA content between the eight snow algal communities, ranging from 50 to 300 mg FA g C-1. In multivariate analyses total FA content opposed the cellular N:C quota and a large part of the FA variability among field locations originated from the abundant FAs C181n-9, C18 2n-6, and C183n-3. Both field samples and snow algal strains grown under -N+HL conditions had high concentrations of C181n-9. FAs possibly accumulated due to the cessation of growth. Differences in color and nutritional composition between patches of snow algal communities within one snow field were not directly related to nutrient conditions. We propose that the highly patchy distribution of snow algae within and between snow fields may also result from differences in topographical and geological parameters such as slope, melting water rivulets, and rock formation. KW - Arctic snow algal bloom KW - cellular C:N:P ratio KW - ecology KW - extremophiles KW - lipids KW - nutrients KW - psychrophilic. KW - Spitsbergen Y1 - 2012 U6 - https://doi.org/10.3389/fmicb.2012.00380 SN - 1664-302X VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Sauer, Patrick A1 - Glombitza, Clemens A1 - Kallmeyer, Jens T1 - A system for incubations at high gas partial pressure JF - Frontiers in microbiology N2 - High-pressure is a key feature of deep subsurface environments. High partial pressure of dissolved gasses plays an important role in microbial metabolism, because thermodynamic feasibility of many reactions depends on the concentration of reactants. For gases, this is controlled by their partial pressure, which can exceed 1 MPa at in situ conditions. Therefore, high hydrostatic pressure alone is not sufficient to recreate true deep subsurface in situ conditions, but the partial pressure of dissolved gasses has to be controlled as well. We developed an incubation system that allows for incubations at hydrostatic pressure up to 60 MPa, temperatures up to 120 degrees C, and at high gas partial pressure. The composition and partial pressure of gasses can be manipulated during the experiment. To keep costs low, the system is mainly made from off-the-shelf components with only very few custommade parts. A flexible and inert PVDF (polyvinylidene fluoride) incubator sleeve, which is almost impermeable for gases, holds the sample and separates it from the pressure fluid. The flexibility of the incubator sleeve allows for sub-sampling of the medium without loss of pressure. Experiments can be run in both static and flow-through mode. The incubation system described here is usable for versatile purposes, not only the incubation of microorganisms and determination of growth rates, but also for chemical degradation or extraction experiments under high gas saturation, e.g., fluid-gas-rock-interactions in relation to carbon dioxide sequestration. As an application of the system we extracted organic compounds from sub-bituminous coal using H2O as well as a H2O-CO2 mixture at elevated temperature (90 degrees C) and pressure (5 MPa). Subsamples were taken at different time points during the incubation and analyzed by ion chromatography. Furthermore we demonstrated the applicability of the system for studies of microbial activity, using samples from the Isis mud volcano. We could detect an increase in sulfate reduction rate upon the addition of methane to the sample. KW - high-pressure incubation system KW - gas partial pressure KW - sub-sampling KW - carbon dioxide KW - low molecular weight organic acids Y1 - 2012 U6 - https://doi.org/10.3389/fmicb.2012.00025 SN - 1664-302X VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Kaplan, Aaron A1 - Harel, Moshe A1 - Kaplan-Levy, Ruth N. A1 - Hadas, Ora A1 - Sukenik, Assaf A1 - Dittmann-Thünemann, Elke T1 - The languages spoken in the water body (or the biological role of cyanobacterial toxins) JF - Frontiers in microbiology N2 - Although intensification of toxic cyanobacterial blooms over the last decade is a matter of growing concern due to bloom impact on water quality, the biological role of most of the toxins produced is not known. In this critical review we focus primarily on the biological role of two toxins, microcystins and cylindrospermopsin, in inter- and intra-species communication and in nutrient acquisition. We examine the experimental evidence supporting some of the dogmas in the field and raise several open questions to be dealt with in future research. We do not discuss the health and environmental implications of toxin presence in the water body. KW - aoa KW - cylindrospermopsin KW - microcystin KW - cyr KW - mcy Y1 - 2012 U6 - https://doi.org/10.3389/fmicb.2012.00138 SN - 1664-302X VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Bickel, Samantha L. A1 - Tang, Kam W. A1 - Grossart, Hans-Peter T1 - Ciliate epibionts associated with crustacean zooplankton in German lakes - distribution, motility, and bacterivory JF - Frontiers in microbiology N2 - Ciliate epibionts associated with crustacean zooplankton are widespread in aquatic systems, but their ecological roles are little known. We studied the occurrence of ciliate epibionts on crustacean zooplankton in nine German lakes with different limnological features during the summer of 2011. We also measured the detachment and re-attachment rates of the ciliates, changes in their motility, and the feeding rates of attached vs. detached ciliate epibionts. Epibionts were found in all lakes sampled except an acidic lake with large humic inputs. Epibiont prevalence was as high as 80.96% on the cladoceran Daphnia cucullata, 67.17% on the cladoceran Diaphanosoma brachyurum, and 46.67% on the calanoid copepod Eudiaptomus gracilis. Both cladoceran groups typically had less than 10 epibionts per individual, while the epibiont load on E. gracilis ranged from 1 to >30 epibionts per individual. After the death of the zooplankton host, the peritrich ciliate epibiont Epistylis sp. detached in an exponential fashion with a half-life of 5 min, and 98% detached within 30 min, leaving behind the stalks used for attachment. Immediately after detachment, the ciliates were immotile, but 62% became motile within 60 min. When a new host was present, only 27% reattached after 120 min. The average measured ingestion rate and clearance rate of Epistylis were 11,745 bacteria ciliate(-1) h(-1) and 24.33 mu l ciliate(-1) h(-1), respectively. Despite their high feeding rates, relatively low epibiont abundances were observed in the field, which suggests either diversion of energy to stalk formation, high metabolic loss by the epibionts, or high mortality among the epibiont populations. KW - ciliate epibionts KW - Epistylis KW - crustacean zooplankton KW - bacterivory KW - epibiont motility Y1 - 2012 U6 - https://doi.org/10.3389/fmicb.2012.00243 SN - 1664-302X VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Mengel, Matthias A1 - Levermann, Anders A1 - Schleussner, Carl-Friedrich A1 - Born, Andreas T1 - Enhanced Atlantic subpolar gyre variability through baroclinic threshold in a coarse resolution model JF - Earth system dynamics N2 - Direct observations, satellite measurements and paleo records reveal strong variability in the Atlantic subpolar gyre on various time scales. Here we show that variations of comparable amplitude can only be simulated in a coupled climate model in the proximity of a dynamical threshold. The threshold and the associated dynamic response is due to a positive feedback involving increased salt transport in the subpolar gyre and enhanced deep convection in its centre. A series of sensitivity experiments is performed with a coarse resolution ocean general circulation model coupled to a statistical-dynamical atmosphere model which in itself does not produce atmospheric variability. To simulate the impact of atmospheric variability, the model system is perturbed with freshwater forcing of varying, but small amplitude and multi-decadal to centennial periodicities and observational variations in wind stress. While both freshwater and wind-stress-forcing have a small direct effect on the strength of the subpolar gyre, the magnitude of the gyre's response is strongly increased in the vicinity of the threshold. Our results indicate that baroclinic self-amplification in the North Atlantic ocean can play an important role in presently observed SPG variability and thereby North Atlantic climate variability on multi-decadal scales. Y1 - 2012 U6 - https://doi.org/10.5194/esd-3-189-2012 SN - 2190-4979 SN - 2190-4987 VL - 3 IS - 2 SP - 189 EP - 197 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Lauterbach, Daniel A1 - Ristow, Michael A1 - Gemeinholzer, Birgit T1 - Population genetics and fitness in fragmented populations of the dioecious and endangered Silene otites (Caryophyllaceae) JF - Plant systematics and evolution N2 - Population fragmentation is often correlated with loss of genetic diversity and reduced fitness. Obligate out-crossing (dioecy) is expected to enhance genetic diversity, reduce genetic differentiation, and avoid inbreeding depression through frequent gene flow. However, in highly fragmented populations dioecy has only diminishing effects upon genetic structure as pollination limitations (e.g. flight distance of pollinators) most often restrict inter-population gene flow in insect pollinated species. In fragmented dry grasslands in northeastern Germany, we analysed genetic structure, fitness, and habitat quality of the endangered dioecious Silene otites (Caryophyllaceae). Using AFLP markers, a high level of differentiation among ten populations was found (F (st) = 0.36), while the intra-population genetic diversities (H (E) = 0.165-0.240) were similar as compared to hermaphroditic species. There was neither a correlation between geographic and genetic distance nor between genetic diversity and population size, which indicates reduced gene flow among populations and random genetic drift. Plant size was positively correlated with genetic diversity. Seed set and number of juveniles were positively related to population size. Higher total coverage resulted in reduced plant fitness, and the number of juveniles was negatively correlated to cryptogam cover. Additionally, we found a sex ratio bias towards more male plants in larger populations. Overall, our results indicate that on a regional geographic scale dioecy does not necessarily prevent genetic erosion in the case of habitat fragmentation, especially in the absence of long distance seed and pollen dispersal capacity. KW - AFLP KW - Population size KW - Mating system KW - Isolation by distance KW - Sex ratio Y1 - 2012 U6 - https://doi.org/10.1007/s00606-011-0533-0 SN - 0378-2697 VL - 298 IS - 1 SP - 155 EP - 164 PB - Springer CY - Wien ER - TY - JOUR A1 - Araujo, Wagner L. A1 - Nunes-Nesi, Adriano A1 - Nikoloski, Zoran A1 - Sweetlove, Lee J. A1 - Fernie, Alisdair R. T1 - Metabolic control and regulation of the tricarboxylic acid cycle in photosynthetic and heterotrophic plant tissues JF - Plant, cell & environment : cell physiology, whole-plant physiology, community physiology N2 - The tricarboxylic acid (TCA) cycle is a crucial component of respiratory metabolism in both photosynthetic and heterotrophic plant organs. All of the major genes of the tomato TCA cycle have been cloned recently, allowing the generation of a suite of transgenic plants in which the majority of the enzymes in the pathway are progressively decreased. Investigations of these plants have provided an almost complete view of the distribution of control in this important pathway. Our studies suggest that citrate synthase, aconitase, isocitrate dehydrogenase, succinyl CoA ligase, succinate dehydrogenase, fumarase and malate dehydrogenase have control coefficients flux for respiration of -0.4, 0.964, -0.123, 0.0008, 0.289, 0.601 and 1.76, respectively; while 2-oxoglutarate dehydrogenase is estimated to have a control coefficient of 0.786 in potato tubers. These results thus indicate that the control of this pathway is distributed among malate dehydrogenase, aconitase, fumarase, succinate dehydrogenase and 2-oxoglutarate dehydrogenase. The unusual distribution of control estimated here is consistent with specific non-cyclic flux mode and cytosolic bypasses that operate in illuminated leaves. These observations are discussed in the context of known regulatory properties of the enzymes and some illustrative examples of how the pathway responds to environmental change are given. KW - metabolic control analysis KW - metabolic regulation KW - respiration KW - Solanum lycopersicum (tomato) KW - TCA cycle Y1 - 2012 U6 - https://doi.org/10.1111/j.1365-3040.2011.02332.x SN - 0140-7791 VL - 35 IS - 1 SP - 1 EP - 21 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Stojanovic, Milovan A1 - Markovic, Rade A1 - Kleinpeter, Erich A1 - Baranac-Stojanovic, Marija T1 - Synthesis of thiazolidine-fused heterocycles via exo-mode cyclizations of vinylogous N-acyliminium ions JF - Organic & biomolecular chemistry : an international journal of synthetic, physical and biomolecular organic chemistry N2 - Syntheses of thiazolidine-fused heterocycles via exo-mode cyclizations of vinylogous N-acyliminium ions incorporating heteroatom-based nucleophiles have been examined and discussed. The formation of (5,6)-membered systems was feasible with all nucleophiles tried (O, S and N), while the closing of the five-membered ring was restricted to O- and S-nucleophiles. The closure of a four-membered ring failed. Instead, the bicyclic (5,6)-membered acetal derivative and the tricyclic system with an eight-membered central ring were obtained from the substrates containing O and S nucleophilic moieties, respectively. The reaction outcome and stereochemistry are rationalized using quantum chemical calculations at B3LYP/6-31G(d) level. The exclusive cis-stereoselectivity in the formation of (5,6)- and (5,5)-membered systems results from thermodynamic control, whereas the formation of the eight-membered ring was kinetically controlled. Y1 - 2012 U6 - https://doi.org/10.1039/c1ob06451g SN - 1477-0520 VL - 10 IS - 3 SP - 575 EP - 589 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Graae, Bente J. A1 - De Frenne, Pieter A1 - Kolb, Annette A1 - Brunet, Jorg A1 - Chabrerie, Olivier A1 - Verheyen, Kris A1 - Pepin, Nick A1 - Heinken, Thilo A1 - Zobel, Martin A1 - Shevtsova, Anna A1 - Nijs, Ivan A1 - Milbau, Ann T1 - On the use of weather data in ecological studies along altitudinal and latitudinal gradients JF - Oikos N2 - Global warming has created a need for studies along climatic gradients to assess the effects of temperature on ecological processes. Altitudinal and latitudinal gradients are often used as such, usually in combination with air temperature data from the closest weather station recorded at 1.52 m above the ground. However, many ecological processes occur in, at, or right above the soil surface. To evaluate how representative the commonly used weather station data are for the microclimate relevant for soil surface biota, we compared weather station temperatures for an altitudinal (500900 m a.s.l.) and a latitudinal gradient (4968 degrees N) with data obtained by temperature sensors placed right below the soil surface at five sites along these gradients. The mean annual temperatures obtained from weather stations and adjusted using a lapse rate of -5.5 degrees C km-1 were between 3.8 degrees C lower and 1.6 degrees C higher than those recorded by the temperature sensors at the soil surface, depending on the position along the gradients. The monthly mean temperatures were up to 10 degrees C warmer or 5 degrees C colder at the soil surface. The within-site variation in accumulated temperature was as high as would be expected from a 300 m change in altitude or from a 4 degrees change in latitude or a climate change scenario corresponding to warming of 1.63.8 degrees C. Thus, these differences introduced by the decoupling are significant from a climate change perspective, and the results demonstrate the need for incorporating microclimatic variation when conducting studies along altitudinal or latitudinal gradients. We emphasize the need for using relevant temperature data in climate impact studies and further call for more studies describing the soil surface microclimate, which is crucial for much of the biota. Y1 - 2012 U6 - https://doi.org/10.1111/j.1600-0706.2011.19694.x SN - 0030-1299 VL - 121 IS - 1 SP - 3 EP - 19 PB - Wiley-Blackwell CY - Hoboken ER -