TY - JOUR A1 - Şener, Ulaş T1 - Rodrik, Dani (2015): Economics Rules: The Rights and Wrongs of the Dismal Science / rezensiert von Ulaş Şener JF - European journal of economics and economic policies : intervention ; EJEEP Y1 - 2017 U6 - https://doi.org/10.4337/ejeep.2017.03.08 SN - 2052-7764 SN - 2195-3376 VL - 14 SP - 375 EP - 377 PB - Elgar CY - Cheltenham ER - TY - JOUR A1 - Zupok, Arkadiusz A1 - Iobbi-Nivol, Chantal A1 - Mejean, Vincent A1 - Leimkühler, Silke T1 - The regulation of Moco biosynthesis and molybdoenzyme gene expression by molybdenum and iron in bacteria JF - Metallomics : integrated biometal science N2 - Bacterial molybdoenzymes are key enzymes involved in the global sulphur, nitrogen and carbon cycles. These enzymes require the insertion of the molybdenum cofactor (Moco) into their active sites and are able to catalyse a large range of redox-reactions. Escherichia coli harbours nineteen different molybdoenzymes that require a tight regulation of their synthesis according to substrate availability, oxygen availability and the cellular concentration of molybdenum and iron. The synthesis and assembly of active molybdoenzymes are regulated at the level of transcription of the structural genes and of translation in addition to the genes involved in Moco biosynthesis. The action of global transcriptional regulators like FNR, NarXL/QP, Fur and ArcA and their roles on the expression of these genes is described in detail. In this review we focus on what is known about the molybdenum- and iron-dependent regulation of molybdoenzyme and Moco biosynthesis genes in the model organism E. coli. The gene regulation in E. coli is compared to two other well studied model organisms Rhodobacter capsulatus and Shewanella oneidensis. Y1 - 2019 U6 - https://doi.org/10.1039/c9mt00186g SN - 1756-5901 SN - 1756-591X VL - 11 IS - 10 SP - 1602 EP - 1624 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Zouhar, Jan A1 - Sauer, Michael T1 - Helping hands for budding prospects: ENTH/ANTH/VHS accessory proteins in endocytosis, vacuolar transport, and secretion JF - The plant cell N2 - Coated vesicles provide a major mechanism for the transport of proteins through the endomembrane system of plants. Transport between the endoplasmic reticulum and the Golgi involves vesicles with COPI and COPII coats, whereas clathrin is the predominant coat in endocytosis and post-Golgi trafficking. Sorting of cargo, coat assembly, budding, and fission are all complex and tightly regulated processes that involve many proteins. The mechanisms and responsible factors are largely conserved in eukaryotes, and increasing organismal complexity tends to be associated with a greater numbers of individual family members. Among the key factors is the class of ENTH/ANTH/VHS domain-containing proteins, which link membrane subdomains, clathrin, and other adapter proteins involved in early steps of clathrin coated vesicle formation. More than 30 Arabidopsis thaliana proteins contain this domain, but their generally low sequence conservation has made functional classification difficult. Reports from the last two years have greatly expanded our knowledge of these proteins and suggest that ENTH/ANTH/VHS domain proteins are involved in various instances of clathrin-related endomembrane trafficking in plants. This review aims to summarize these new findings and discuss the broader context of clathrin-dependent plant vesicular transport. Y1 - 2014 U6 - https://doi.org/10.1105/tpc.114.131680 SN - 1040-4651 SN - 1532-298X VL - 26 IS - 11 SP - 4232 EP - 4244 PB - American Society of Plant Physiologists CY - Rockville ER - TY - JOUR A1 - Zhang, Gong A1 - Ignatova, Zoya T1 - Folding at the birth of the nascent chain: coordinating translation with co-translational folding JF - Current opinion in structural biology : review of all advances ; evaluation of key references ; comprehensive listing of papers N2 - In the living cells, the folding of many proteins is largely believed to begin co-translationally, during their biosynthesis at the ribosomes. In the ribosomal tunnel, the nascent peptide may establish local interactions and stabilize alpha-helical structures. Long-range contacts are more likely outside the ribosomes after release of larger segments of the nascent chain. Examples suggest that domains can attain native-like structure on the ribosome with and without population of folding intermediates. The co-translational folding is limited by the speed of the gradual extrusion of the nascent peptide which imposes conformational restraints on its folding landscape. Recent experimental and in silico modeling studies indicate that translation kinetics fine-tunes co-translational folding by providing a time delay for sequential folding of distinct portions of the nascent chain. Y1 - 2011 U6 - https://doi.org/10.1016/j.sbi.2010.10.008 SN - 0959-440X VL - 21 IS - 1 SP - 25 EP - 31 PB - Elsevier CY - London ER - TY - JOUR A1 - Zerbian, Sabine T1 - Variation in the grammar of black south African English JF - Southern African linguistics and applied language studies Y1 - 2012 U6 - https://doi.org/10.2989/16073614.2012.693721 SN - 1607-3614 VL - 30 IS - 1 SP - 131 EP - 135 PB - NISC CY - Grahamstown ER - TY - JOUR A1 - Zakrzewski, Tanja T1 - Rezension zu: Poettering, Jorun: Migrating Merchants - Trade, Nation, and Religion in Seventeenth-Century Hamburg and Portugal . - Berlin: De Gryter, 2018. - 397 S. - ISBN: 978-3-11-047001-7 JF - Comparativ: Zeitschrift für Globalgeschichte und vergleichende Gesellschaftsforschung Y1 - 2022 UR - https://www.comparativ.net/v2/article/view/3241/2941 SN - 0940-3566 VL - 2 SP - 289 EP - 291 PB - Universitätsverlag CY - Leipzig ER - TY - JOUR A1 - Zakarias, Lilla A1 - Kelly, Helen A1 - Sails, Christos A1 - Code, Chris T1 - The methodological quality of short-term/working memory treatments in poststroke aphasia BT - a systematic review JF - Journal of speech, language, and hearing research N2 - Purpose: The aims of this systematic review are to provide a critical overview of short-term memory (STM) and working memory (WM) treatments in stroke aphasia and to systematically evaluate the internal and external validity of STM/WM treatments. Method: A systematic search was conducted in February 2014 and then updated in December 2016 using 13 electronic databases. We provided descriptive characteristics of the included studies and assessed their methodological quality using the Risk of Bias in N-of-1 Trials quantitative scale (Tate et al., 2015), which was completed by 2 independent raters. Results: The systematic search and inclusion/exclusion procedure yielded 17 single-case or case-series studies with 37 participants for inclusion. Nine studies targeted auditory STM consisting of repetition and/or recognition tasks, whereas 8 targeted attention and WM, such as attention process training including n-back tasks with shapes and clock faces as well as mental math tasks. In terms of their methodological quality, quality scores on the Risk of Bias in N-of-1 Trials scale ranged from 4 to 17 (M = 9.5) on a 0-30 scale, indicating a high risk of bias in the reviewed studies. Effects of treatment were most frequently assessed on STM, WM, and spoken language comprehension. Transfer effects on communication and memory in activities of daily living were tested in only 5 studies. Conclusions: Methodological limitations of the reviewed studies make it difficult, at present, to draw firm conclusions about the effects of STM/WM treatments in poststroke aphasia. Further studies with more rigorous methodology and stronger experimental control are needed to determine the beneficial effects of this type of intervention. To understand the underlying mechanisms of STM/WM treatment effects and how they relate to language functioning, a careful choice of outcome measures and specific hypotheses about potential improvements on these measures are required. Future studies need to include outcome measures of memory functioning in everyday life and psychosocial functioning more generally to demonstrate the ecological validity of STM and WM treatments. Y1 - 2019 U6 - https://doi.org/10.1044/2018_JSLHR-L-18-0057 SN - 1092-4388 SN - 1558-9102 VL - 62 IS - 6 SP - 1979 EP - 2001 PB - American Speech-Language-Hearing Assoc. CY - Rockville ER - TY - JOUR A1 - Yokoyama, Kenichi A1 - Leimkühler, Silke T1 - The role of FeS clusters for molybdenum cofactor biosynthesis and molybdoenzymes in bacteria JF - Biochimica et biophysica acta : Molecular cell research N2 - The biosynthesis of the molybdenum cofactor (Moco) has been intensively studied, in addition to its insertion into molybdoenzymes. In particular, a link between the assembly of molybdoenzymes and the biosynthesis of FeS clusters has been identified in the recent years: 1) the synthesis of the first intermediate in Moco biosynthesis requires an FeS-cluster containing protein, 2) the sulfurtransferase for the dithiolene group in Moco is also involved in the synthesis of FeS clusters, thiamin and thiolated tRNAs, 3) the addition of a sulfido-ligand to the molybdenum atom in the active site additionally involves a sulfurtransferase, and 4) most molybdoenzymes in bacteria require FeS clusters as redox active cofactors. In this review we will focus on the biosynthesis of the molybdenum cofactor in bacteria, its modification and insertion into molybdoenzymes, with an emphasis to its link to FeS cluster biosynthesis and sulfur transfer. (C) 2014 Elsevier B.V. All rights reserved. KW - Molybdenum-iron-iron-sulfur cluster KW - Molybdenum cofactor KW - tRNA KW - Sulfur transfer KW - L-Cysteine desulfurase Y1 - 2015 U6 - https://doi.org/10.1016/j.bbamcr.2014.09.021 SN - 0167-4889 SN - 0006-3002 VL - 1853 IS - 6 SP - 1335 EP - 1349 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Yarman, Aysu A1 - Scheller, Frieder W. T1 - How reliable is the electrochemical readout of MIP sensors? JF - Sensors N2 - Electrochemical methods offer the simple characterization of the synthesis of molecularly imprinted polymers (MIPs) and the readouts of target binding. The binding of electroinactive analytes can be detected indirectly by their modulating effect on the diffusional permeability of a redox marker through thin MIP films. However, this process generates an overall signal, which may include nonspecific interactions with the nonimprinted surface and adsorption at the electrode surface in addition to (specific) binding to the cavities. Redox-active low-molecular-weight targets and metalloproteins enable a more specific direct quantification of their binding to MIPs by measuring the faradaic current. The in situ characterization of enzymes, MIP-based mimics of redox enzymes or enzyme-labeled targets, is based on the indication of an electroactive product. This approach allows the determination of both the activity of the bio(mimetic) catalyst and of the substrate concentration. KW - molecularly imprinted polymers KW - electropolymerization KW - direct electron KW - transfer KW - catalysis KW - redox marker KW - gate effect Y1 - 2020 U6 - https://doi.org/10.3390/s20092677 SN - 1424-8220 VL - 20 IS - 9 PB - MDPI CY - Basel ER - TY - JOUR A1 - Yarman, Aysu A1 - Kurbanoglu, Sevinc A1 - Jetzschmann, Katharina J. A1 - Ozkan, Sibel A. A1 - Wollenberger, Ulla A1 - Scheller, Frieder W. T1 - Electrochemical MIP-Sensors for Drugs JF - Current Medicinal Chemistry N2 - In order to replace bio-macromolecules by stable synthetic materials in separation techniques and bioanalysis biomimetic receptors and catalysts have been developed: Functional monomers are polymerized together with the target analyte and after template removal cavities are formed in the "molecularly imprinted polymer" (MIP) which resemble the active sites of antibodies and enzymes. Starting almost 80 years ago, around 1,100 papers on MIPs were published in 2016. Electropolymerization allows to deposit MIPs directly on voltammetric electrodes or chips for quartz crystal microbalance (QCM) and surface plasmon resonance (SPR). For the readout of MIPs for drugs amperometry, differential pulse voltammetry (DPV) and impedance spectroscopy (EIS) offer higher sensitivity as compared with QCM or SPR. Application of simple electrochemical devices allows both the reproducible preparation of MIP sensors, but also the sensitive signal generation. Electrochemical MIP-sensors for the whole arsenal of drugs, e.g. the most frequently used analgesics, antibiotics and anticancer drugs have been presented in literature and tested under laboratory conditions. These biomimetic sensors typically have measuring ranges covering the lower nano-up to millimolar concentration range and they are stable under extreme pH and in organic solvents like nonaqueous extracts. KW - Biomimetic sensors KW - molecularly imprinted polymers KW - drug sensors KW - drug imprinting KW - electropolymerization KW - electrochemical sensors Y1 - 2018 U6 - https://doi.org/10.2174/0929867324666171005103712 SN - 0929-8673 SN - 1875-533X VL - 25 IS - 33 SP - 4007 EP - 4019 PB - Bentham Science Publishers LTD CY - Sharjah ER - TY - JOUR A1 - Yarman, Aysu A1 - Jetzschmann, Katharina J. A1 - Neumann, Bettina A1 - Zhang, Xiaorong A1 - Wollenberger, Ulla A1 - Cordin, Aude A1 - Haupt, Karsten A1 - Scheller, Frieder W. T1 - Enzymes as Tools in MIP-Sensors JF - Chemosensors N2 - Molecularly imprinted polymers (MIPs) have the potential to complement antibodies in bioanalysis, are more stable under harsh conditions, and are potentially cheaper to produce. However, the affinity and especially the selectivity of MIPs are in general lower than those of their biological pendants. Enzymes are useful tools for the preparation of MIPs for both low and high-molecular weight targets: As a green alternative to the well-established methods of chemical polymerization, enzyme-initiated polymerization has been introduced and the removal of protein templates by proteases has been successfully applied. Furthermore, MIPs have been coupled with enzymes in order to enhance the analytical performance of biomimetic sensors: Enzymes have been used in MIP-sensors as tracers for the generation and amplification of the measuring signal. In addition, enzymatic pretreatment of an analyte can extend the analyte spectrum and eliminate interferences. KW - enzymatic MIP synthesis KW - template digestion KW - enzyme tracer KW - enzymatic analyte conversion KW - molecularly imprinted polymers Y1 - 2017 U6 - https://doi.org/10.3390/chemosensors5020011 SN - 2227-9040 VL - 5 PB - MDPI CY - Basel ER - TY - JOUR A1 - Yarman, Aysu A1 - Dechtrirat, Decha A1 - Bosserdt, Maria A1 - Jetzschmann, Katharina J. A1 - Gajovic-Eichelmann, Nenad A1 - Scheller, Frieder W. T1 - Cytochrome c-derived hybrid systems based on moleculary imprinted polymers JF - Electroanalysis : an international journal devoted to fundamental and practical aspects of electroanalysis N2 - Hybrid architectures which combine a MIP with an immobilized affinity ligand or a biocatalyst sum up the advantages of both components. In this paper, hybrid architectures combining a layer of a molecularly imprinted electropolymer with a mini-enzyme or a self-assembled monolayer will be presented. (i) Microperoxidase-11 (MP-11) catalyzed oxidation of the drug aminopyrine on a product-imprinted sublayer: The peroxide dependent conversion of the analyte aminopyrine takes place in the MP-11 containing layer on top of a product-imprinted electropolymer on the indicator electrode. The hierarchical architecture resulted in the elimination of interfering signals for ascorbic acid and uric acid. An advantage of the new hierarchical structure is the separation of MIP formation by electropolymerization and immobilization of the catalyst. In this way it was for the first time possible to integrate an enzyme with a MIP layer in a sensor configuration. This combination has the potential to be transferred to other enzymes, e.g. P450, opening the way to clinically important analytes. (ii) Epitope-imprinted poly-scopoletin layer for binding of the C-terminal peptide and cytochrome c (Cyt c): The MIP binds both the target peptide and the parent protein almost eight times stronger than the non-imprinted polymer with affinities in the lower micromolar range. Exchange of only one amino acid in the peptide decreases the binding by a factor of five. (iii) MUA-poly-scopoletin MIP for cytochrome c: Cyt c bound to the MIP covered gold electrode exhibits direct electron transfer with a redox potential and rate constant typical for the native protein. The MIP cover layer suppresses the displacement of the target protein by BSA or myoglobin. The combination of protein imprinted polymers with an efficient electron transfer is a new concept for characterizing electroactive proteins such as Cyt c. The competition with other proteins shows that the MIP binds its target Cyt c preferentially and that molecular shape and the charge of protein determine the binding of interfering proteins. KW - Molecularly imprinted polymers KW - Microperoxidase-11 KW - Cytochrome c KW - Catalytically active MIPs KW - Epitope imprinting KW - Monoclonal MIPs Y1 - 2015 U6 - https://doi.org/10.1002/elan.201400592 SN - 1040-0397 SN - 1521-4109 VL - 27 IS - 3 SP - 573 EP - 586 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Yang, Ziyin A1 - Baldermann, Susanne A1 - Watanabe, Naoharu T1 - Recent studies of the volatile compounds in tea JF - FOOD RESEARCH INTERNATIONAL N2 - Tea aroma is one of the most important factors affecting the character and quality of tea. Recent advances in methods and instruments for separating and identifying volatile compounds have led to intensive investigations of volatile compounds in tea. These studies have resulted in a number of insightful and useful discoveries. Here we summarize the recent investigations into tea volatile compounds: the volatile compounds in tea products; the metabolic pathways of volatile formation in tea plants and the glycosidically-bound volatile compounds in tea; and the techniques used for studying such compounds. Finally, we discuss practical applications for the improvement of aroma and flavor quality in teas. (C) 2013 Elsevier Ltd. All rights reserved. KW - Biosynthesis KW - Precursor KW - Stress KW - Tea KW - Volatile Y1 - 2013 U6 - https://doi.org/10.1016/j.foodres.2013.02.011 SN - 0963-9969 VL - 53 IS - 2 SP - 585 EP - 599 PB - ELSEVIER SCIENCE BV CY - AMSTERDAM ER - TY - JOUR A1 - Yang, Xiaoping A1 - Darko, Kwame Oteng A1 - Huang, Yanjun A1 - He, Caimei A1 - Yang, Huansheng A1 - He, Shanping A1 - Li, Jianzhong A1 - Li, Jian A1 - Hocher, Berthold A1 - Yin, Yulong T1 - Resistant starch regulates gut microbiota BT - structure, biochemistry and cell signalling JF - Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry and pharmacology N2 - Starch is one of the most popular nutritional sources for both human and animals. Due to the variation of its nutritional traits and biochemical specificities, starch has been classified into rapidly digestible, slowly digestible and resistant starch. Resistant starch has its own unique chemical structure, and various forms of resistant starch are commercially available. It has been found being a multiple-functional regulator for treating metabolic dysfunction. Different functions of resistant starch such as modulation of the gut microbiota, gut peptides, circulating growth factors, circulating inflammatory mediators have been characterized by animal studies and clinical trials. In this mini-review, recent remarkable progress in resistant starch on gut microbiota, particularly the effect of structure, biochemistry and cell signaling on nutrition has been summarized, with highlights on its regulatory effect on gut microbiota. KW - Resistant starch KW - Gut microbiota KW - Nutrition Y1 - 2017 U6 - https://doi.org/10.1159/000477386 SN - 1015-8987 SN - 1421-9778 VL - 42 IS - 1 SP - 306 EP - 318 PB - Karger CY - Basel ER - TY - JOUR A1 - Yan, Wenhao A1 - Chen, Dijun A1 - Kaufmann, Kerstin T1 - Molecular mechanisms of floral organ specification by MADS domain proteins JF - Current opinion in plant biology N2 - Flower development is a model system to understand organ specification in plants. The identities of different types of floral organs are specified by homeotic MADS transcription factors that interact in a combinatorial fashion. Systematic identification of DNA-binding sites and target genes of these key regulators show that they have shared and unique sets of target genes. DNA binding by MADS proteins is not based on ‘simple’ recognition of a specific DNA sequence, but depends on DNA structure and combinatorial interactions. Homeotic MADS proteins regulate gene expression via alternative mechanisms, one of which may be to modulate chromatin structure and accessibility in their target gene promoters. Y1 - 2016 U6 - https://doi.org/10.1016/j.pbi.2015.12.004 SN - 1369-5266 SN - 1879-0356 VL - 29 SP - 154 EP - 162 PB - Elsevier CY - London ER - TY - JOUR A1 - Yamamichi, Masato A1 - Klauschies, Toni A1 - Miner, Brooks E. A1 - van Velzen, Ellen T1 - Modelling inducible defences in predator-prey interactions BT - assumptions and dynamical consequences of three distinct approaches JF - Ecology letters N2 - Inducible defences against predation are widespread in the natural world, allowing prey to economise on the costs of defence when predation risk varies over time or is spatially structured. Through interspecific interactions, inducible defences have major impacts on ecological dynamics, particularly predator-prey stability and phase lag. Researchers have developed multiple distinct approaches, each reflecting assumptions appropriate for particular ecological communities. Yet, the impact of inducible defences on ecological dynamics can be highly sensitive to the modelling approach used, making the choice of model a critical decision that affects interpretation of the dynamical consequences of inducible defences. Here, we review three existing approaches to modelling inducible defences: Switching Function, Fitness Gradient and Optimal Trait. We assess when and how the dynamical outcomes of these approaches differ from each other, from classic predator-prey dynamics and from commonly observed eco-evolutionary dynamics with evolving, but non-inducible, prey defences. We point out that the Switching Function models tend to stabilise population dynamics, and the Fitness Gradient models should be carefully used, as the difference with evolutionary dynamics is important. We discuss advantages of each approach for applications to ecological systems with particular features, with the goal of providing guidelines for future researchers to build on. KW - Adaptive dynamics KW - fitness gradient KW - inducible defence KW - optimal trait KW - phenotypic plasticity KW - predator-prey dynamics KW - reaction norm KW - switching function Y1 - 2019 U6 - https://doi.org/10.1111/ele.13183 SN - 1461-023X SN - 1461-0248 VL - 22 IS - 2 SP - 390 EP - 404 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Wyrwa, Ulrich T1 - Rezension zu: D’Antonio, Emanuele: Il sangue di Giuditta. Antisemitismo e voci ebraiche nell’Italia di metà Ottocento. - Roma: Carocci editore, 2020. - 157 S. - ISBN 978-88-290-0329-7 JF - Quest : Issues in Contemporary Jewish History ; journal of Fondazione CDEC T2 - The blood of Judith. Anti-Semitism and Jewish voices in Italy in the mid-nineteenth century Y1 - 2021 U6 - https://doi.org/10.48248/issn.2037-741X/13161 SN - 2037-741X IS - 20 SP - 207 EP - 210 PB - Fondazione Centro di Documentazione Ebraica Contemporanea CY - Milano ER - TY - JOUR A1 - Wyrwa, Ulrich T1 - Rezension zu: Brenner, Michael: Der lange Schatten der Revolution : Juden und Antisemiten in Hitlers München 1918 bis 1923. - Berlin: Jüdischer Verlag im Suhrkamp Verlag, 2019. - 300 S. - ISBN 978-3-633-54295-6 JF - Quest : Issues in Contemporary Jewish History ; journal of Fondazione CDEC Y1 - 2020 U6 - https://doi.org/10.48248/issn.2037-741X/1842 SN - 2037-741X IS - 17 SP - 222 EP - 225 PB - Fondazione Centro di Documentazione Ebraica Contemporanea CY - Milano ER - TY - JOUR A1 - Wyrwa, Ulrich T1 - Rezension zu: Grady,Tim: A Deadly Legacy: German Jews and the Great War.New Haven, Conn.: Yale University Press, 2017. Pp. xii, 291. - ISBN 978-0-300-19204-9 JF - The American historical review Y1 - 2019 U6 - https://doi.org/10.1093/ahr/rhz191 SN - 0002-8762 SN - 1937-5239 VL - 124 IS - 2 SP - 761 EP - 763 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Wyrwa, Ulrich T1 - Rezension zu: Tim Grady. A Deadly Legacy: German Jews and the Great War. - New Haven: Yale University Press, 2017. - Xii, 291 S. -ISBN: 978-0-300-19204-9 Tracy Hayes Norrell. For the Honor of Our Fatherland: German Jews on the Eastern Front during the Great War. - Lanham: Lexington Books, 2017. - XiX,187 S. - ISBN: 978-1-4985-6487-8 JF - The American historical review Y1 - 2019 U6 - https://doi.org/10.1093/ahr/rhz191 SN - 0002-8762 SN - 1937-5239 VL - 124 IS - 2 SP - 761 EP - 763 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Wyrwa, Ulrich T1 - Rezension zu: Enzyklopädie jüdischer Geschichte und Kultur, ed. Dan Diner, Sächsische Akademie der Wissenschaften zu Leipzig, (Stuttgart –Weimar: Metzler, 2011-2017), 7 Vol T1 - Encyclopedia of Jewish History and Culture JF - Quest-Issues in Contemporary Jewish History Y1 - 2018 U6 - https://doi.org/10.48248/issn.2037-741X/682 SN - 2037-741X VL - 2018 IS - 14 SP - 123 EP - 131 PB - Fondazione Centro Documentazione Ebraica Contemporanea CY - Milano ER - TY - JOUR A1 - Wulff, Dirk U. A1 - De Deyne, Simon A1 - Jones, Michael N. A1 - Mata, Rui A1 - Austerweil, Joseph L. A1 - Baayen, R. Harald A1 - Balota, David A. A1 - Baronchelli, Andrea A1 - Brysbaert, Marc A1 - Cai, Qing A1 - Dennis, Simon A1 - Hills, Thomas T. A1 - Kenett, Yoed N. A1 - Keuleers, Emmanuel A1 - Marelli, Marco A1 - Pakhomov, Serguei A1 - Ramscar, Michael A1 - Schooler, Lael J. A1 - Shing, Yee Lee A1 - da Souza, Alessandra S. A1 - Siew, Cynthia S. Q. A1 - Storms, Gert A1 - Veríssimo, Joao Marques T1 - New Perspectives on the Aging Lexicon JF - Trends in cognitive science N2 - The field of cognitive aging has seen considerable advances in describing the linguistic and semantic changes that happen during the adult life span to uncover the structure of the mental lexicon (i.e., the mental repository of lexical and conceptual representations). Nevertheless, there is still debate concerning the sources of these changes, including the role of environmental exposure and several cognitive mechanisms associated with learning, representation, and retrieval of information. We review the current status of research in this field and outline a framework that promises to assess the contribution of both ecological and psychological aspects to the aging lexicon. Y1 - 2019 U6 - https://doi.org/10.1016/j.tics.2019.05.003 SN - 1364-6613 SN - 1879-307X VL - 23 IS - 8 SP - 686 EP - 698 PB - Elsevier CY - London ER - TY - JOUR A1 - Wu, Lei A1 - Glebe, Ulrich A1 - Böker, Alexander T1 - Surface-initiated controlled radical polymerizations from silica nanoparticles, gold nanocrystals, and bionanoparticles JF - Polymer Chemistry N2 - In recent years, core/shell nanohybrids containing a nanoparticle core and a distinct surrounding shell of polymer brushes have received extensive attention in nanoelectronics, nanophotonics, catalysis, nanopatterning, drug delivery, biosensing, and many others. From the large variety of existing polymerization methods on the one hand and strategies for grafting onto nanoparticle surfaces on the other hand, the combination of grafting-from with controlled radical polymerization (CRP) techniques has turned out to be the best suited for synthesizing these well-defined core/shell nanohybrids and is known as surface-initiated CRP. Most common among these are surface-initiated atom transfer radical polymerization (ATRP), surface-initiated reversible addition-fragmentation chain transfer (RAFT) polymerization, and surface-initiated nitroxide-mediated polymerization (NMP). This review highlights the state of the art of growing polymers from nanoparticles using surface-initiated CRP techniques. We focus on mechanistic aspects, synthetic procedures, and the formation of complex architectures as well as novel properties. From the vast number of examples of nanoparticle/polymer hybrids formed by surface-initiated CRP techniques, we present nanohybrid formation from the particularly important and most studied silica nanoparticles, gold nanocrystals, and proteins which can be regarded as bionanoparticles. Y1 - 2015 U6 - https://doi.org/10.1039/c5py00525f SN - 1759-9954 SN - 1759-9962 VL - 6 IS - 29 SP - 5143 EP - 5184 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Wozniak, Natalia Joanna A1 - Sicard, Adrien T1 - Evolvability of flower geometry BT - Convergence in pollinator-driven morphological evolution of flowers JF - Seminars in cell & developmental biology N2 - Flowers represent a key innovation during plant evolution. Driven by reproductive optimization, evolution of flower morphology has been central in boosting species diversification. In most cases, this has happened through specialized interactions with animal pollinators and subsequent reduction of gene flow between specialized morphs. While radiation has led to an enormous variability in flower forms and sizes, recurrent evolutionary patterns can be observed. Here, we discuss the targets of selection involved in major trends of pollinator-driven flower evolution. We review recent findings on their adaptive values, developmental grounds and genetic bases, in an attempt to better understand the repeated nature of pollinator-driven flower evolution. This analysis highlights how structural innovation can provide flexibility in phenotypic evolution, adaptation and speciation. (C) 2017 Elsevier Ltd. All rights reserved. KW - Flower KW - Developmental evolution KW - Morphogenesis KW - Angiosperms KW - Co-evolution KW - Plant-pollinator interactions Y1 - 2018 U6 - https://doi.org/10.1016/j.semcdb.2017.09.028 SN - 1084-9521 VL - 79 SP - 3 EP - 15 PB - Elsevier CY - London ER - TY - JOUR A1 - Woodhouse, Jason Nicholas A1 - Makower, A. Katharina A1 - Yeung, Anna C. Y. A1 - Ongley, Sarah E. A1 - Micallef, Melinda L. A1 - Moffitt, Michelle C. A1 - Neilan, Brett A. T1 - Advances in genomics, transcriptomics and proteomics of toxin-producing cyanobacteria JF - Environmental microbiology reports N2 - A common misconception persists that the genomes of toxic and non-toxic cyanobacterial strains are largely conserved with the exception of the presence or absence of the genes responsible for toxin production. Implementation of -omics era technologies has challenged this paradigm, with comparative analyses providing increased insight into the differences between strains of the same species. The implementation of genomic, transcriptomic and proteomic approaches has revealed distinct profiles between toxin-producing and non-toxic strains. Further, metagenomics and metaproteomics highlight the genomic potential and functional state of toxic bloom events over time. In this review, we highlight how these technologies have shaped our understanding of the complex relationship between these molecules, their producers and the environment at large within which they persist. Y1 - 2016 U6 - https://doi.org/10.1111/1758-2229.12366 SN - 1758-2229 VL - 8 SP - 3 EP - 13 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Wong, Kevin A1 - Mason, Emily A1 - Brune, Sascha A1 - East, Madison A1 - Edmonds, Marie A1 - Zahirovic, Sabin T1 - Deep Carbon Cycling Over the Past 200 Million Years: A Review of Fluxes in Different Tectonic Settings JF - Frontiers in Earth Science KW - deep carbon cycle KW - carbonate assimilation KW - solid Earth degassing KW - plate reconstructions KW - carbon dioxide KW - subduction zone Y1 - 2019 U6 - https://doi.org/10.3389/feart.2019.00263 SN - 2296-6463 VL - 7 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Wolff, Christian Michael A1 - Caprioglio, Pietro A1 - Stolterfoht, Martin A1 - Neher, Dieter T1 - Nonradiative Recombination in Perovskite Solar Cells BT - the Role of Interfaces JF - Advanced materials N2 - Perovskite solar cells combine high carrier mobilities with long carrier lifetimes and high radiative efficiencies. Despite this, full devices suffer from significant nonradiative recombination losses, limiting their V-OC to values well below the Shockley-Queisser limit. Here, recent advances in understanding nonradiative recombination in perovskite solar cells from picoseconds to steady state are presented, with an emphasis on the interfaces between the perovskite absorber and the charge transport layers. Quantification of the quasi-Fermi level splitting in perovskite films with and without attached transport layers allows to identify the origin of nonradiative recombination, and to explain the V-OC of operational devices. These measurements prove that in state-of-the-art solar cells, nonradiative recombination at the interfaces between the perovskite and the transport layers is more important than processes in the bulk or at grain boundaries. Optical pump-probe techniques give complementary access to the interfacial recombination pathways and provide quantitative information on transfer rates and recombination velocities. Promising optimization strategies are also highlighted, in particular in view of the role of energy level alignment and the importance of surface passivation. Recent record perovskite solar cells with low nonradiative losses are presented where interfacial recombination is effectively overcome-paving the way to the thermodynamic efficiency limit. KW - interfacial recombination KW - open-circuit voltage KW - perovskite solar cells KW - photoluminescence Y1 - 2019 U6 - https://doi.org/10.1002/adma.201902762 SN - 0935-9648 SN - 1521-4095 VL - 31 IS - 52 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Wolf, Hans-Georg T1 - Omoniyi, T., The sociolinguistics of borderlands: two nations, one community; Trento, Africa World Press, 2004 BT - The sociolinguistics of borderlands: two nations, one community Y1 - 2005 SN - 1466-4208 ER - TY - JOUR A1 - Woith, Heiko A1 - Petersen, Gesa Maria A1 - Hainzl, Sebastian A1 - Dahm, Torsten T1 - Review: Can Animals Predict Earthquakes? JF - Bulletin of the Seismological Society of America N2 - In public perception, abnormal animal behavior is widely assumed to be a potential earthquake precursor, in strong contrast to the viewpoint in natural sciences. Proponents of earthquake prediction via animals claim that animals feel and react abnormally to small changes in environmental and physico-chemical parameters related to the earthquake preparation process. In seismology, however, observational evidence for changes of physical parameters before earthquakes is very weak. In this study, we reviewed 180 publications regarding abnormal animal behavior before earthquakes and analyze and discuss them with respect to (1) magnitude-distance relations, (2) foreshock activity, and (3) the quality and length of the published observations. More than 700 records of claimed animal precursors related to 160 earthquakes are reviewed with unusual behavior of more than 130 species. The precursor time ranges from months to seconds prior to the earthquakes, and the distances from a few to hundreds of kilometers. However, only 14 time series were published, whereas all other records are single observations. The time series are often short (the longest is 1 yr), or only small excerpts of the full data set are shown. The probability density of foreshocks and the occurrence of animal precursors are strikingly similar, suggesting that at least parts of the reported animal precursors are in fact related to foreshocks. Another major difficulty for a systematic and statistical analysis is the high diversity of data, which are often only anecdotal and retrospective. The study clearly demonstrates strong weaknesses or even deficits in many of the published reports on possible abnormal animal behavior. To improve the research on precursors, we suggest a scheme of yes and no questions to be assessed to ensure the quality of such claims. Y1 - 2018 U6 - https://doi.org/10.1785/0120170313 SN - 0037-1106 SN - 1943-3573 VL - 108 IS - 3A SP - 1031 EP - 1045 PB - Seismological Society of America CY - Albany ER - TY - JOUR A1 - Witzel, Katja A1 - Neugart, Susanne A1 - Ruppel, Silke A1 - Schreiner, Monika A1 - Wiesner, Melanie A1 - Baldermann, Susanne T1 - Recent progress in the use of 'omics technologies in brassicaceous vegetables JF - Frontiers in plant science N2 - Continuing advances in 'omics methodologies and instrumentation is enhancing the understanding of how plants cope with the dynamic nature of their growing environment. 'Omics platforms have been only recently extended to cover horticultural crop species. Many of the most widely cultivated vegetable crops belong to the genus Brassica: these include plants grown for their root (turnip, rutabaga/swede), their swollen stem base (kohlrabi), their leaves (cabbage, kale, pak choi) and their inflorescence (cauliflower, broccoli). Characterization at the genome, transcript, protein and metabolite levels has illustrated the complexity of the cellular response to a whole series of environmental stresses, including nutrient deficiency, pathogen attack, heavy metal toxicity, cold acclimation, and excessive and sub optimal irradiation. This review covers recent applications of omics technologies to the brassicaceous vegetables, and discusses future scenarios in achieving improvements in crop end-use quality. KW - genomics KW - transcriptomics KW - metabolomics KW - proteomics KW - crop KW - microbiomics Y1 - 2015 U6 - https://doi.org/10.3389/fpls.2015.00244 SN - 1664-462X VL - 6 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Wischerhoff, Erik A1 - Badi, Nezha A1 - Laschewsky, André A1 - Lutz, Jean-Francois ED - Börner, Hans Gerhard ED - Lutz, JF T1 - Smart polymer surfaces concepts and applications in biosciences JF - Advances in polymer science = Fortschritte der Hochpolymeren-Forschung JF - Advances in Polymer Science N2 - Stimuli-responsive macromolecules (i.e., pH-, thermo-, photo-, chemo-, and bioresponsive polymers) have gained exponential importance in materials science, nanotechnology, and biotechnology during the last two decades. This chapter describes the usefulness of this class of polymer for preparing smart surfaces (e.g., modified planar surfaces, particles surfaces, and surfaces of three-dimensional scaffolds). Some efficient pathways for connecting these macromolecules to inorganic, polymer, or biological substrates are described. In addition, some emerging bioapplications of smart polymer surfaces (e.g., antifouling surfaces, cell engineering, protein chromatography, tissue engineering, biochips, and bioassays) are critically discussed. KW - Antifouling surfaces KW - Bioactive surfaces KW - Biocompatible polymers KW - Bioseparation KW - Cell engineering KW - Polymer-modified surfaces KW - Stimuli-responsive polymers Y1 - 2011 SN - 978-3-642-20154-7 U6 - https://doi.org/10.1007/12_2010_88 SN - 0065-3195 VL - 240 IS - 1 SP - 1 EP - 33 PB - Springer CY - Berlin ER - TY - JOUR A1 - Wischer, Ilse T1 - Simone E. Pfenninger: Grammaticalization paths of english and high german existential constructions : a corpus-based study / rezensiert von Ilse Wischer JF - Zeitschrift für Dialektologie und Linguistik : ZDL N2 - Rezensiertes Werk: Simone E. Pfenninger: Grammaticalization paths of english and high german existential constructions : a corpus-based study / Bern: Lang, 2009. - XI, 369 S. - (European University Studies: Series 21, Linguistics Vol. 345) Y1 - 2010 SN - 0044-1449 SN - 2366-2395 VL - 77 IS - 3 SP - 372 EP - 375 ER - TY - JOUR A1 - Wischer, Ilse T1 - Facchinetti, R., (Hrsg.), Krug, M. (Hrsg.), Palmer, F. (Hrsg.), Modality in Contemporary English; Berlin, de Gruyter, 2006 BT - Modality in Contemporary English Y1 - 2006 ER - TY - JOUR A1 - Wischer, Ilse T1 - Miyawaki, M., James Harris's Theory of Universal Grammar: a Synthesis of the Aristotelian and Platonic Conceptions of Language; Münster, Nodus-Publ., 2005 BT - James Harris's Theory of Universal Grammar: a Synthesis of the Aristotelian and Platonic Conceptions of Language Y1 - 2006 ER - TY - JOUR A1 - Wischer, Ilse T1 - Brinton, L. J., Traugott, E. C., Lexicalization and Language Change; Cambridge, Univ.-Press, 2006 BT - Lexicalization and Language Change Y1 - 2006 ER - TY - JOUR A1 - Wischer, Ilse T1 - López-Couso, M. J. (Hrsg.) , Seoane, E. (Hrsg.), Rethinking Grammaticalization; Theoretical and Empirical Issues in Grammaticalization, Amsterdam, Benjamins, 2008 BT - Rethinking Grammaticalization; Theoretical and Empirical Issues in Grammaticalization T2 - Theoretical and Empirical Issues in Grammaticalization Y1 - 2010 ER - TY - JOUR A1 - Wischer, Ilse T1 - Tieken-Boon van Ostade, I. (Hrsg.), Two Hundred Years of Lindley Murray; Münster, Nodus, 1996 BT - Two Hundred Years of Lindley Murray Y1 - 1998 ER - TY - JOUR A1 - Wischer, Ilse T1 - Rissanen, M. (Hrsg.), Hintikka, M. (Hrsg.), Kahlas-Tarkka, L. (Hrsg.), McConchie, R. (Hrsg.), Change in Meaning and the Meaning of Change; Helsinki, Société Néophilologique, 2007 BT - Change in Meaning and the Meaning of Change Y1 - 2009 ER - TY - JOUR A1 - Wischer, Ilse T1 - Ziegeler, D., Interfaces with English Aspect. Diachronic and empirical studies; Amsterdam, Benjamins Publ. Company, 2006 BT - Interfaces with English Aspect. Diachronic and empirical studies Y1 - 2010 ER - TY - JOUR A1 - Winzer, Lylla A1 - Krahé, Barbara A1 - Guest, Philip Michael T1 - The Scale of Sexual Aggression in Southeast Asia: A Review JF - Trauma, violence & abuse N2 - Southeast Asia is one of the most dynamic regions in the world. It is experiencing rapid socioeconomic change that may influence the level of sexual aggression, but data on the scale of sexual aggression in the region remain sparse. The aim of the present article was to systematically review the findings of studies available in English on the prevalence of self-reported sexual aggression and victimization among women and men above the age of 12 years in the 11 countries of Southeast Asia (Brunei, Cambodia, East Timor, Indonesia, Laos, Malaysia, Myanmar, the Philippines, Singapore, Thailand, and Vietnam). Based on four scientific databases, the search engine Google, Opengrey database, and reference checking, 49 studies were found on sexual victimization. Of those, 32 included only women. Self-reported perpetration was assessed by only three studies and included all-male samples. Prevalence rates varied widely across studies but showed that sexual victimization was widespread among different social groups, irrespective of sex and sexual orientation. Methodological heterogeneity, lack of representativeness of samples, imbalance of information available by country, missing information within studies, and cultural differences hampered the comparability between and within countries. There is a need for operationalizations that specifically address sexual aggression occurring after the age of consent, based on detailed behavioral descriptions of unwanted sexual experiences and allied to a qualitative approach with cultural sensitivity. Data on sexual aggression in conflict settings and in human trafficking are also limited. Recommendations for future research are presented in the discussion. KW - rape KW - sexual victimization KW - sexual aggression KW - sexual violence KW - Southeast Asia Y1 - 2019 U6 - https://doi.org/10.1177/1524838017725312 SN - 1524-8380 SN - 1552-8324 VL - 20 IS - 5 SP - 595 EP - 612 PB - Sage Publ. CY - Thousand Oaks ER - TY - JOUR A1 - Winter, Bodo A1 - Matlock, Teenie A1 - Shaki, Samuel A1 - Fischer, Martin H. T1 - Mental number space in three dimensions JF - Neuroscience & biobehavioral reviews : official journal of the International Behavioral Neuroscience Society N2 - A large number of experimental findings from neuroscience and experimental psychology demonstrated interactions between spatial cognition and numerical cognition. In particular, many researchers posited a horizontal mental number line, where small numbers are thought of as being to the left of larger numbers. This review synthesizes work on the mental association between space and number, indicating the existence of multiple spatial mappings: recent research has found associations between number and vertical space, as well as associations between number and near/far space. We discuss number space in three dimensions with an eye on potential origins of the different number mappings, and how these number mappings fit in with our current knowledge of brain organization and brain-culture interactions. We derive novel predictions and show how this research fits into a general view of cognition as embodied, grounded and situated. (C) 2015 Elsevier Ltd. All rights reserved. KW - Embodiment KW - Intra-parietal sulcus KW - Mental number line KW - Metaphor KW - Neglect KW - Spatial cognition KW - SNARC Y1 - 2015 U6 - https://doi.org/10.1016/j.neubiorev.2015.09.005 SN - 0149-7634 SN - 1873-7528 VL - 57 SP - 209 EP - 219 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Winkler, Roland G. A1 - Cherstvy, Andrey G. ED - Muller, M. T1 - Strong and weak polyelectrolyte adsorption onto oppositely charged curved surfaces JF - Advances in polymer science JF - Advances in Polymer Science N2 - Polyelectrolytes are macromolecules composed of charged monomers and exhibit unique properties due to the interplay of their flexibility and electrostatic interactions. In solution, they are attracted to oppositely charged surfaces and interfaces and exhibit a transition to an adsorbed state when certain conditions are met concerning the charge densities of the polymer and surface and the properties of the solution. In this review, we discuss two limiting cases for adsorption of flexible polyelectrolytes on curved surfaces: weak and strong adsorption. In the first case, adsorption is strongly influenced by the entropic degrees of freedom of a flexible polyelectrolyte. By contrast, in the strong adsorption limit, electrostatic interactions dominate, which leads to particular adsorption patterns, specifically on spherical surfaces. We discuss the corresponding theoretical approaches, applying a mean-field description for the polymer and the polymer-surface interaction. For weak adsorption, we discuss the critical adsorption behavior by exactly solvable models for planar and spherical geometries and a generic approximation scheme, which is additionally applied to cylindrical surfaces. For strong adsorption, we investigate various polyelectrolyte patterns on cylinders and spheres and evaluate their stability. The results are discussed in the light of experimental results, mostly of DNA adsorption experiments. Y1 - 2014 SN - 978-3-642-40734-5; 978-3-642-40733-8 U6 - https://doi.org/10.1007/12_2012_183 SN - 0065-3195 VL - 255 SP - 1 EP - 56 PB - Springer CY - Berlin ER - TY - JOUR A1 - Wiesner-Reinhold, Melanie A1 - Schreiner, Monika A1 - Baldermann, Susanne A1 - Schwarz, Dietmar A1 - Hanschen, Franziska S. A1 - Kipp, Anna Patricia A1 - Rowan, Daryl D. A1 - Bentley-Hewitt, Kerry L. A1 - McKenzie, Marian J. T1 - Mechanisms of Selenium Enrichment and Measurement in Brassicaceous Vegetables, and Their Application to Human Health JF - Frontiers in plant science N2 - Selenium (Se) is an essential micronutrient for human health. Se deficiency affects hundreds of millions of people worldwide, particularly in developing countries, and there is increasing awareness that suboptimal supply of Se can also negatively affect human health. Selenium enters the diet primarily through the ingestion of plant and animal products. Although, plants are not dependent on Se they take it up from the soil through the sulphur (S) uptake and assimilation pathways. Therefore, geographic differences in the availability of soil Se and agricultural practices have a profound influence on the Se content of many foods, and there are increasing efforts to biofortify crop plants with Se. Plants from the Brassicales are of particular interest as they accumulate and synthesize Se into forms with additional health benefits, such as methylselenocysteine (MeSeCys). The Brassicaceae are also well-known to produce the glucosinolates; S-containing compounds with demonstrated human health value. Furthermore, the recent discovery of the selenoglucosinolates in the Brassicaceae raises questions regarding their potential bioefficacy. In this review we focus on Se uptake and metabolism in the Brassicaceae in the context of human health, particularly cancer prevention and immunity. We investigate the close relationship between Se and S metabolism in this plant family, with particular emphasis on the selenoglucosinolates, and consider the methodologies available for identifying and quantifying further novel Se-containing compounds in plants. Finally, we summarize the research of multiple groups investigating biofortification of the Brassicaceae and discuss which approaches might be most successful for supplying Se deficient populations in the future. KW - Brassica vegetables KW - selenium KW - biofortification KW - glucosinolates KW - human health KW - immune system KW - cancer KW - analytical methods Y1 - 2017 U6 - https://doi.org/10.3389/fpls.2017.01365 SN - 1664-462X VL - 8 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Wiemann, Dirk T1 - Chanan, M.; The Politics of Documentary; London, BFI, 2007 BT - The Politics of Documentary Y1 - 2010 SN - 0944-9094 ER - TY - JOUR A1 - Wiemann, Dirk T1 - George, Rosemary Marangoly, Indian English and the Fiction of National Literature / [rezensiert von] Dirk Wiemann JF - Zeitschrift für Anglistik und Amerikanistik : ZAA ; a quarterly of language, literature and culture N2 - Rezensiertes Werk George, Rosemary Marangoly, Indian English and the Fiction of National Literature - Cambridge: Cambridge University Press, 2013. - Hb. viii, 285 pp. - (Zeitschrift für Anglistik und Amerikanistik ; 62(4)) ISBN 978-1-107-04000-7. Y1 - 2014 U6 - https://doi.org/10.1515/zaa-2014-0039 SN - 0044-2305 SN - 2196-4726 VL - 62 IS - 4 SP - 385 EP - 388 PB - DeGruyter CY - Tübingen ER - TY - JOUR A1 - Wick, Kristin A1 - Leeger-Aschmann, Claudia S. A1 - Monn, Nico D. A1 - Radtke, Thomas A1 - Ott, Laura V. A1 - Rebholz, Cornelia E. A1 - Cruz, Sergio A1 - Gerber, Natalie A1 - Schmutz, Einat A. A1 - Puder, Jardena J. A1 - Munsch, Simone A1 - Kakebeeke, Tanja H. A1 - Jenni, Oskar G. A1 - Granacher, Urs A1 - Kriemler, Susi T1 - Interventions to Promote Fundamental Movement Skills in Childcare and Kindergarten: A Systematic Review and Meta-Analysis JF - Sports medicine N2 - Background Proficiency in fundamental movement skills (FMS) lays the foundation for being physically active and developing more complex motor skills. Improving these motor skills may provide enhanced opportunities for the development of a variety of perceptual, social, and cognitive skills. Objective The objective of this systematic review and meta-analysis was to assess the effects of FMS interventions on actual FMS, targeting typically developing young children. Method Searches in seven databases (CINAHL, Embase, MEDLINE, PsycINFO, PubMed, Scopus, Web of Science) up to August 2015 were completed. Trials with children (aged 2-6 years) in childcare or kindergarten settings that applied FMS-enhancing intervention programs of at least 4 weeks and meeting the inclusion criteria were included. Standardized data extraction forms were used. Risk of bias was assessed using a standard scoring scheme (Effective Public Health Practice Project-Quality Assessment Tool for Quantitative Studies [EPHPP]). We calculated effects on overall FMS, object control and locomotor subscales (OCS and LMS) by weighted standardized mean differences (SMDbetween) using random-effects models. Certainty in training effects was evaluated using GRADE (Grading of Recommendations Assessment, Development, and Evaluation System). Results Thirty trials (15 randomized controlled trials and 15 controlled trials) involving 6126 preschoolers (aged 3.3-5.5 years) revealed significant differences among groups in favor of the intervention group (INT) with small-to-large effects on overall FMS (SMDbetween 0.46), OCS (SMDbetween 1.36), and LMS (SMDbetween 0.94). Our certainty in the treatment estimates based on GRADE is very low. Conclusions Although there is relevant effectiveness of programs to improve FMS proficiency in healthy young children, they need to be interpreted with care as they are based on low-quality evidence and immediate post-intervention effects without long-term follow-up. Y1 - 2017 U6 - https://doi.org/10.1007/s40279-017-0723-1 SN - 0112-1642 SN - 1179-2035 VL - 47 SP - 2045 EP - 2068 PB - Springer CY - Northcote ER - TY - JOUR A1 - Wesselmann, Katharina ED - Ambühl, Annemarie T1 - Review of Rachel Bryant Davies: Victorian Epic Burlesques. A Critical Anthology of Nineteenth-Century Theatrical Entertainments after Homer BT - Bloomsbury (London & New York 2019) (= Bloomsbury Studies in Classical Reception), xi & 284 p., 12 illustrations. ISBN: 9781350027176, £ 26.09 (pb)/£ 81.00 (hb) JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien = Transformative Translations in Jewish History and Culture Y1 - 2020 U6 - https://doi.org/10.34679/thersites.vol11.181 SN - 2364-7612 VL - 2020 IS - 11 SP - 379 EP - 384 ER - TY - JOUR A1 - Wenzel, Bertolt T1 - Organizing coordination in fisheries and marine environmental management: Patterns of organizational change in Europe JF - Bulletin of the Seismological Society of America N2 - Over the past decade, an increasing number of public organizations involved in marine governance in Europe have adapted their formal coordination structures for fisheries and marine environmental management. This study examines why the International Council for the Exploration of the Sea (ICES), DG FISH of the European Commission, the Norwegian Institute of Marine Research (IMR), and the Swedish Agency for Marine and Water Management (SwAM) have changed their sectoral structures into organizations with a geographical focus on marine ecosystems. The study finds that the gradual convergence of formal coordination structures for fisheries and marine environmental management is driven by coercive, normative and mimetic processes of isomorphism. The structural changes reflect an organizational adaptation to a changing institutional environment and an Ecosystem Approach to Management (EAM) focusing on regional marine areas, cross-sector integration and coordination. (C) 2016 Elsevier Ltd. All rights reserved. KW - Public organizations KW - Coordination KW - Fisheries management KW - Marine environmental management KW - Isomorphism Y1 - 2016 U6 - https://doi.org/10.1016/j.ocecoaman.2016.10.012 SN - 0964-5691 SN - 1873-524X VL - 134 SP - 194 EP - 206 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Wendehorst, Stephan T1 - Jay Berkowitz, Law’s Dominion: Jewish Community, Religion, and Family in Early Modern Metz (Leiden: Brill, 2019), 404 p., $ 76. JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien = Transformative Translations in Jewish History and Culture Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-486154 SN - 978-3-86956-493-7 SN - 1614-6492 SN - 1862-7684 VL - 2020 IS - 26 SP - 146 EP - 149 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Welker, Martin A1 - Dittmann-Thünemann, Elke A1 - von Doehren, Hans ED - Hopwood, DA T1 - Cyanobacteria as a source of natural products JF - Methods in enzymology JF - Methods in Enzymology N2 - Cyanobacteria or blue-green algae from various environments have been recognized as sources of a variety of bioactive metabolites. Strategies of strain isolation from aquatic habitats, and cultivation and harvesting for metabolite production are described. Strategies for screening of compounds are discussed, including their direct MALDI-TOF mass spectrometric detection in whole cells. Genetic approaches including genomic mining, mutagenesis including transcriptional activation, heterologous expression, and in vitro. reconstitution of pathways are presented. Y1 - 2012 SN - 978-0-12-404634-4 U6 - https://doi.org/10.1016/B978-0-12-404634-4.00002-4 SN - 0076-6879 VL - 517 IS - 1 SP - 23 EP - 46 PB - Elsevier CY - San Diego ER - TY - JOUR A1 - Weisshuhn, Peter A1 - Mueller, Felix A1 - Wiggering, Hubert T1 - Ecosystem Vulnerability Review BT - proposal of an interdisciplinary ecosystem assessment approach JF - Environmental Management N2 - To safeguard the sustainable use of ecosystems and their services, early detection of potentially damaging changes in functional capabilities is needed. To support a proper ecosystem management, the analysis of an ecosystem’s vulnerability provide information on its weaknesses as well as on its capacity to recover after suffering an impact. However, the application of the vulnerability concept to ecosystems is still an emerging topic. After providing background on the vulnerability concept, we summarize existing ecosystem vulnerability research on the basis of a systematic literature review with a special focus on ecosystem type, disciplinary background, and more detailed definition of the ecosystem vulnerability components. Using the Web of ScienceTM Core Collection, we overviewed the literature from 1991 onwards but used the 5 years from 2011 to 2015 for an in-depth analysis, including 129 articles. We found that ecosystem vulnerability analysis has been applied most notably in conservation biology, climate change research, and ecological risk assessments, pinpointing a limited spreading across the environmental sciences. It occurred primarily within marine and freshwater ecosystems. To avoid confusion, we recommend using the unambiguous term ecosystem vulnerability rather than ecological, environmental, population, or community vulnerability. Further, common ground has been identified, on which to define the ecosystem vulnerability components exposure, sensitivity, and adaptive capacity. We propose a framework for ecosystem assessments that coherently connects the concepts of vulnerability, resilience, and adaptability as different ecosystem responses. A short outlook on the possible operationalization of the concept by ecosystem vulnerabilty indices, and a conclusion section complete the review. KW - Environmental vulnerability KW - Ecological vulnerability KW - Ecosystem response KW - Interdisciplinarity KW - Resilience KW - Adaptability Y1 - 2018 U6 - https://doi.org/10.1007/s00267-018-1023-8 SN - 0364-152X SN - 1432-1009 VL - 61 IS - 6 SP - 904 EP - 915 PB - Springer CY - New York ER - TY - JOUR A1 - Wegmann, Simone T1 - Sven Siefken und Hilmar Rommetvedt (Hrsg.). 2021. Parliamentary committees in the policy process JF - Zeitschrift für vergleichende Politikwissenschaft Y1 - 2023 U6 - https://doi.org/10.1007/s12286-022-00553-5 SN - 1865-2646 SN - 1865-2654 VL - 16 IS - 4 SP - 769 EP - 772 PB - VS Verl. für Sozialwissenschaften CY - Wiesbaden ER - TY - JOUR A1 - Warren, Ben H. A1 - Simberloff, Daniel A1 - Ricklefs, Robert E. A1 - Aguilee, Robin A1 - Condamine, Fabien L. A1 - Gravel, Dominique A1 - Morlon, Helene A1 - Mouquet, Nicolas A1 - Rosindell, James A1 - Casquet, Juliane A1 - Conti, Elena A1 - Cornuault, Josselin A1 - Maria Fernandez-Palacios, Jose A1 - Hengl, Tomislav A1 - Norder, Sietze J. A1 - Rijsdijk, Kenneth F. A1 - Sanmartin, Isabel A1 - Strasberg, Dominique A1 - Triantis, Kostas A. A1 - Valente, Luis M. A1 - Whittaker, Robert J. A1 - Gillespie, Rosemary G. A1 - Emerson, Brent C. A1 - Thebaud, Christophe T1 - Islands as model systems in ecology and evolution: prospects fifty years after MacArthur-Wilson JF - Ecology letters N2 - The study of islands as model systems has played an important role in the development of evolutionary and ecological theory. The 50th anniversary of MacArthur and Wilson's (December 1963) article, An equilibrium theory of insular zoogeography', was a recent milestone for this theme. Since 1963, island systems have provided new insights into the formation of ecological communities. Here, building on such developments, we highlight prospects for research on islands to improve our understanding of the ecology and evolution of communities in general. Throughout, we emphasise how attributes of islands combine to provide unusual research opportunities, the implications of which stretch far beyond islands. Molecular tools and increasing data acquisition now permit re-assessment of some fundamental issues that interested MacArthur and Wilson. These include the formation of ecological networks, species abundance distributions, and the contribution of evolution to community assembly. We also extend our prospects to other fields of ecology and evolution - understanding ecosystem functioning, speciation and diversification - frequently employing assets of oceanic islands in inferring the geographic area within which evolution has occurred, and potential barriers to gene flow. Although island-based theory is continually being enriched, incorporating non-equilibrium dynamics is identified as a major challenge for the future. KW - Community assembly KW - diversification KW - ecosystem functioning KW - genomics KW - island biogeography KW - islands as model systems KW - speciation Y1 - 2015 U6 - https://doi.org/10.1111/ele.12398 SN - 1461-023X SN - 1461-0248 VL - 18 IS - 2 SP - 200 EP - 217 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Wallach, Kerry T1 - Isabella Gartner: Menorah : Jüdisches Familienblatt für Wissenschaft, Kunst und Literatur (1923–1932) ; Materialien zur Geschichte einer Wiener zionistischen Zeitschrift / [rezensiert von] Kerry Wallach JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. N2 - rezensiertes Werk: Gartner, Isabella: Menorah : Jüdisches Familienblatt für Wissenschaft, Kunst und Literatur (1923–1932) ; Materialien zur Geschichte einer Wiener zionistischen Zeitschrift. - Würzburg : Königshausen & Neumann, 2009. - 356 S. ISBN 978-3-8260-3864-8 Y1 - 2010 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-43715 SN - 1614-6492 SN - 1862-7684 IS - 16 SP - 226 EP - 229 ER - TY - JOUR A1 - Wagner, Nicole D. A1 - Hillebrand, Helmut A1 - Wacker, Alexander A1 - Frost, Paul C. T1 - Nutritional indicators and their uses in ecology JF - Ecology letters N2 - The nutrition of animal consumers is an important regulator of ecological processes due to its effects on their physiology, life-history and behaviour. Understanding the ecological effects of poor nutrition depends on correctly diagnosing the nature and strength of nutritional limitation. Despite the need to assess nutritional limitation, current approaches to delineating nutritional constraints can be non-specific and imprecise. Here, we consider the need and potential to develop new complementary approaches to the study of nutritional constraints on animal consumers by studying and using a suite of established and emerging biochemical and molecular responses. These nutritional indicators include gene expression, transcript regulators, protein profiling and activity, and gross biochemical and elemental composition. The potential applications of nutritional indicators to ecological studies are highlighted to demonstrate the value that this approach would have to future studies in community and ecosystem ecology. KW - Ecological stoichiometry KW - lipid profiling KW - metabolism KW - nutrient-stress KW - nutrition KW - proteomics KW - transcriptomics Y1 - 2013 U6 - https://doi.org/10.1111/ele.12067 SN - 1461-023X VL - 16 IS - 4 SP - 535 EP - 544 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - von Websky, Karoline A1 - Reichetzeder, Christoph A1 - Hocher, Berthold T1 - Physiology and pathophysiology of incretins in the kidney JF - Current opinion in nephrology and hypertension : reviews of all advances, evaluations of key references, comprehensive listing of papers N2 - Purpose of reviewIncretin-based therapy with glucagon-like peptide-1 receptor (GLP-1R) agonists and dipeptidyl peptidase-4 (DPP-4) inhibitors is considered a promising therapeutic option for type 2 diabetes mellitus. Cumulative evidence, mainly from preclinical animal studies, reveals that incretin-based therapies also may elicit beneficial effects on kidney function. This review gives an overview of the physiology, pathophysiology, and pharmacology of the renal incretin system.Recent findingsActivation of GLP-1R in the kidney leads to diuretic and natriuretic effects, possibly through direct actions on renal tubular cells and sodium transporters. Moreover, there is evidence that incretin-based therapy reduces albuminuria, glomerulosclerosis, oxidative stress, and fibrosis in the kidney, partially through GLP-1R-independent pathways. Molecular mechanisms by which incretins exert their renal effects are understood incompletely, thus further studies are needed.SummaryThe GLP-1R and DPP-4 are expressed in the kidney in various species. The kidney plays an important role in the excretion of incretin metabolites and most GLP-1R agonists and DPP-4 inhibitors, thus special attention is required when applying incretin-based therapy in renal impairment. Preclinical observations suggest direct renoprotective effects of incretin-based therapies in the setting of hypertension and other disorders of sodium retention, as well as in diabetic and nondiabetic nephropathy. Clinical studies are needed in order to confirm translational relevance from preclinical findings for treatment options of renal diseases. KW - DDP-4 inhibition KW - diabetes KW - diabetic nephropathy KW - GLP-1 receptor KW - hypertension KW - incretins KW - kidney KW - renal impairment Y1 - 2014 U6 - https://doi.org/10.1097/01.mnh.0000437542.77175.a0 SN - 1062-4821 SN - 1473-6543 VL - 23 IS - 1 SP - 54 EP - 60 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Volkert, Dorothee A1 - Beck, Anne Marie A1 - Cederholm, Tommy A1 - Cereda, Emanuele A1 - Cruz-Jentoft, Alfonso J. A1 - Goisser, Sabine A1 - de Groot, Lisette A1 - Grosshauser, Franz A1 - Kiesswetter, Eva A1 - Norman, Kristina A1 - Pourhassan, Maryam A1 - Reinders, Ilse A1 - Roberts, Helen C. A1 - Rolland, Yves A1 - Schneider, Stéphane M. A1 - Sieber, Cornel A1 - Thiem, Ulrich A1 - Visser, Marjolein A1 - Wijnhoven, Hanneke A1 - Wirth, Rainer T1 - Management of malnutrition in older patients BT - Current approaches, evidence and open questions JF - Journal of Clinical Medicine : open access journal N2 - Malnutrition is widespread in older people and represents a major geriatric syndrome with multifactorial etiology and severe consequences for health outcomes and quality of life. The aim of the present paper is to describe current approaches and evidence regarding malnutrition treatment and to highlight relevant knowledge gaps that need to be addressed. Recently published guidelines of the European Society for Clinical Nutrition and Metabolism (ESPEN) provide a summary of the available evidence and highlight the wide range of different measures that can be taken—from the identification and elimination of potential causes to enteral and parenteral nutrition—depending on the patient’s abilities and needs. However, more than half of the recommendations therein are based on expert consensus because of a lack of evidence, and only three are concern patient-centred outcomes. Future research should further clarify the etiology of malnutrition and identify the most relevant causes in order to prevent malnutrition. Based on limited and partly conflicting evidence and the limitations of existing studies, it remains unclear which interventions are most effective in which patient groups, and if specific situations, diseases or etiologies of malnutrition require specific approaches. Patient-relevant outcomes such as functionality and quality of life need more attention, and research methodology should be harmonised to allow for the comparability of studies. KW - Geriatric patients KW - older persons KW - malnutrition KW - therapy KW - interventions Y1 - 2019 U6 - https://doi.org/10.3390/jcm8070974 SN - 2077-0383 VL - 8 IS - 7 PB - MDPI CY - Basel ER - TY - JOUR A1 - Vogt, Julia H. M. A1 - Schippers, Jos H. M. T1 - Setting the PAS, the role of circadian PAS domain proteins during environmental adaptation in plants JF - Frontiers in plant science N2 - The per-ARNT-sim (PAS) domain represents an ancient protein module that can be found across all kingdoms of life. The domain functions as a sensing unit for a diverse array of signals, including molecular oxygen, small metabolites, and light. In plants, several PAS domain-containing proteins form an integral part of the circadian clock and regulate responses to environmental change. Moreover, these proteins function in pathways that control development and plant stress adaptation responses. Here, we discuss the role of PAS domain-containing proteins in anticipation, and adaptation to environmental changes in plants. KW - PAS domain KW - circadian clock KW - signal transduction KW - environmental stress response KW - growth adaptation Y1 - 2015 U6 - https://doi.org/10.3389/fpls.2015.00513 SN - 1664-462X VL - 6 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Vitello, Eugenia ED - Ambühl, Annemarie ED - Carlà-Uhink, Filippo ED - Rollinger, Christian ED - Walde, Christine T1 - Review of Emilio Zucchetti & Anna Maria Cimino (eds.): Antonio Gramsci and the Ancient World BT - London/New York: Routledge, Taylor & Francis Group, 2021 (= Routledge Monographs in Classical Studies), xiv + 387 pp., ISBN: 978-0-36-719314-0, £ 96.00 (hb.) JF - thersites 14 Y1 - 2022 U6 - https://doi.org/10.34679/thersites.vol14.203 SN - 2364-7612 VL - 2022 IS - 14 SP - 188 EP - 196 ER - TY - JOUR A1 - Vicente, Luis T1 - Sluicing - Cross-linguistic perspectives JF - Language : journal of the Linguistic Society of America Y1 - 2013 SN - 0097-8507 SN - 1535-0665 VL - 89 IS - 3 SP - 653 EP - 655 PB - Linguistic Society of America CY - Washington ER - TY - JOUR A1 - Vicente, Luis T1 - Phase theory JF - Journal of linguistics Y1 - 2011 U6 - https://doi.org/10.1017/S0022226711000193 SN - 0022-2267 VL - 47 IS - 3 SP - 719 EP - 724 PB - Cambridge Univ. Press CY - New York ER - TY - JOUR A1 - Vasishth, Shravan A1 - von der Malsburg, Titus Raban A1 - Engelmann, Felix T1 - What eye movements can tell us about sentence comprehension JF - Wiley interdisciplinary reviews : Cognitive Science N2 - Eye movement data have proven to be very useful for investigating human sentence processing. Eyetracking research has addressed a wide range of questions, such as recovery mechanisms following garden-pathing, the timing of processes driving comprehension, the role of anticipation and expectation in parsing, the role of semantic, pragmatic, and prosodic information, and so on. However, there are some limitations regarding the inferences that can be made on the basis of eye movements. One relates to the nontrivial interaction between parsing and the eye movement control system which complicates the interpretation of eye movement data. Detailed computational models that integrate parsing with eye movement control theories have the potential to unpack the complexity of eye movement data and can therefore aid in the interpretation of eye movements. Another limitation is the difficulty of capturing spatiotemporal patterns in eye movements using the traditional word-based eyetracking measures. Recent research has demonstrated the relevance of these patterns and has shown how they can be analyzed. In this review, we focus on reading, and present examples demonstrating how eye movement data reveal what events unfold when the parser runs into difficulty, and how the parsing system interacts with eye movement control. WIREs Cogn Sci 2013, 4:125134. doi: 10.1002/wcs.1209 For further resources related to this article, please visit the WIREs website. Y1 - 2013 U6 - https://doi.org/10.1002/wcs.1209 SN - 1939-5078 VL - 4 IS - 2 SP - 125 EP - 134 PB - Wiley CY - San Fransisco ER - TY - JOUR A1 - Vasishth, Shravan A1 - Nicenboim, Bruno A1 - Engelmann, Felix A1 - Burchert, Frank T1 - Computational Models of Retrieval Processes in Sentence Processing JF - Trends in Cognitive Sciences N2 - Sentence comprehension requires that the comprehender work out who did what to whom. This process has been characterized as retrieval from memory. This review summarizes the quantitative predictions and empirical coverage of the two existing computational models of retrieval and shows how the predictive performance of these two competing models can be tested against a benchmark data-set. We also show how computational modeling can help us better understand sources of variability in both unimpaired and impaired sentence comprehension. Y1 - 2019 U6 - https://doi.org/10.1016/j.tics.2019.09.003 SN - 1364-6613 SN - 1879-307X VL - 23 IS - 11 SP - 968 EP - 982 PB - Elsevier CY - London ER - TY - JOUR A1 - Vankar, Yashwant D. A1 - Linker, Torsten T1 - Recent Developments in the Synthesis of 2-C-Branched and 1,2-Annulated Carbohydrates JF - European journal of organic chemistry N2 - The importance of carbohydrate chemistry in biological and medicinal chemistry has led to enormous developments in the synthesis of carbohydrate mimics. In this context, the synthesis of branched sugars in general and of 2-C-branched carbohydrates in particular, as well as the synthesis of 1,2-annulated sugars, have received immense attention. They serve not only as carbohydrate mimics in the form of stand-alone molecules, but also as useful intermediates in the synthesis of many natural products, their analogues, and glycosidase inhibitors. This microreview covers the recent synthetic efforts in this area and puts the subject matter into proper perspective for future developments. KW - Synthetic methods KW - Annulation KW - Carbohydrates KW - Carbohydrate mimics Y1 - 2015 U6 - https://doi.org/10.1002/ejoc.201501176 SN - 1434-193X SN - 1099-0690 IS - 35 SP - 7633 EP - 7642 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Vandewalle, Alexander ED - Ambühl, Annemarie ED - Carlà-Uhink, Filippo ED - Rollinger, Christian ED - Walde, Christine T1 - Review of Ross Clare: Ancient Greece and Rome in Videogames. Representation, Play, Transmedia BT - Bloomsbury Academic (London, New York 2021) (= IMAGINES – Classical Receptions in the Visual and Performing Arts), x + 230 pages, 25 illustrations. ISBN: 9781350157194 (hardback), $ 115.00, £ 85.00 hardback, also available as e-book (PDF, Epub, Mobi) JF - thersites 16 Y1 - 2023 U6 - https://doi.org/10.34679/thersites.vol16.220 SN - 2364-7612 VL - 2023 IS - 16 SP - 173 EP - 177 ER - TY - JOUR A1 - van Rees, Charles B. A1 - Waylen, Kerry A. A1 - Schmidt-Kloiber, Astrid A1 - Thackeray, Stephen J. A1 - Kalinkat, Gregor A1 - Martens, Koen A1 - Domisch, Sami A1 - Lillebo, Ana A1 - Hermoso, Virgilio A1 - Grossart, Hans-Peter A1 - Schinegger, Rafaela A1 - Decleer, Kris A1 - Adriaens, Tim A1 - Denys, Luc A1 - Jaric, Ivan A1 - Janse, Jan H. A1 - Monaghan, Michael T. A1 - De Wever, Aaike A1 - Geijzendorffer, Ilse A1 - Adamescu, Mihai C. A1 - Jähnig, Sonja C. T1 - Safeguarding freshwater life beyond 2020 BT - recommendations for the new global biodiversity framework from the European experience JF - Conservation letters N2 - Plans are currently being drafted for the next decade of action on biodiversity-both the post-2020 Global Biodiversity Framework of the Convention on Biological Diversity (CBD) and Biodiversity Strategy of the European Union (EU). Freshwater biodiversity is disproportionately threatened and underprioritized relative to the marine and terrestrial biota, despite supporting a richness of species and ecosystems with their own intrinsic value and providing multiple essential ecosystem services. Future policies and strategies must have a greater focus on the unique ecology of freshwater life and its multiple threats, and now is a critical time to reflect on how this may be achieved. We identify priority topics including environmental flows, water quality, invasive species, integrated water resources management, strategic conservation planning, and emerging technologies for freshwater ecosystem monitoring. We synthesize these topics with decades of first-hand experience and recent literature into 14 special recommendations for global freshwater biodiversity conservation based on the successes and setbacks of European policy, management, and research. Applying and following these recommendations will inform and enhance the ability of global and European post-2020 biodiversity agreements to halt and reverse the rapid global decline of freshwater biodiversity. KW - climate change KW - conservation KW - ecosystem services KW - rivers KW - sustainable KW - development goals KW - water resources KW - wetlands Y1 - 2020 U6 - https://doi.org/10.1111/conl.12771 SN - 1755-263X VL - 14 IS - 1 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - van Leeuwen, Peter Jan A1 - Kunsch, Hans R. A1 - Nerger, Lars A1 - Potthast, Roland A1 - Reich, Sebastian T1 - Particle filters for high-dimensional geoscience applications: A review JF - Quarterly journal of the Royal Meteorological Society N2 - Particle filters contain the promise of fully nonlinear data assimilation. They have been applied in numerous science areas, including the geosciences, but their application to high-dimensional geoscience systems has been limited due to their inefficiency in high-dimensional systems in standard settings. However, huge progress has been made, and this limitation is disappearing fast due to recent developments in proposal densities, the use of ideas from (optimal) transportation, the use of localization and intelligent adaptive resampling strategies. Furthermore, powerful hybrids between particle filters and ensemble Kalman filters and variational methods have been developed. We present a state-of-the-art discussion of present efforts of developing particle filters for high-dimensional nonlinear geoscience state-estimation problems, with an emphasis on atmospheric and oceanic applications, including many new ideas, derivations and unifications, highlighting hidden connections, including pseudo-code, and generating a valuable tool and guide for the community. Initial experiments show that particle filters can be competitive with present-day methods for numerical weather prediction, suggesting that they will become mainstream soon. KW - hybrids KW - localization KW - nonlinear data assimilation KW - particle filters KW - proposal densities Y1 - 2019 U6 - https://doi.org/10.1002/qj.3551 SN - 0035-9009 SN - 1477-870X VL - 145 IS - 723 SP - 2335 EP - 2365 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - van Helden, Jan A1 - Reichard, Christoph T1 - Management control and public sector performance management JF - Baltic Journal of Management N2 - Purpose The purpose of this paper is to investigate whether and how evolving ideas about management control (MC) emerge in research about public sector performance management (PSPM). Design/methodology/approach This is a literature review on PSPM research through using a set of key terms derived from a review of recent developments in MC. Findings MC research, originating in the management accounting discipline, is largely disconnected from PSPM research as part of public administration and public management disciplines. Overlaps between MC and PSPM research are visible in a cybernetic control approach, control variety and contingency-based reasoning. Both academic communities share an understanding of certain issues, although under diverging labels, especially enabling controls or, in a more general sense, usable performance controls, horizontal controls and control packaging. Specific MC concepts are valuable for future PSPM research, i.e. trust as a complement of performance-based controls in complex settings, and strategy as a variable in contingency-based studies. Research limitations/implications Breaking the boundaries between two currently remote research disciplines, on the one hand, might dismantle “would-be” innovations in one of these disciplines, and, on the other hand, may provide a fertile soil for mutual transfer of knowledge. A limitation of the authors’ review of PSPM research is that it may insufficiently cover research published in the public sector accounting journals, which could be an outlet for MC-inspired PSPM research. Originality/value The paper unravels the “apparent” and “real” differences between MC and PSPM research, and, in doing so, takes the detected “real” differences as a starting point for discussing in what ways PSPM research can benefit from MC achievements. KW - Public sector KW - Performance management KW - Management control Y1 - 2018 U6 - https://doi.org/10.1108/BJM-01-2018-0021 SN - 1746-5265 SN - 1746-5273 VL - 14 IS - 1 SP - 158 EP - 176 PB - Emerald Group Publishing Limited CY - Bingley ER - TY - JOUR A1 - Van Donk, Ellen A1 - Ianora, Adrianna A1 - Vos, Matthijs T1 - Induced defences in marine and freshwater phytoplankton a review JF - Hydrobiologia : acta hydrobiologica, hydrographica, limnologica et protistologica N2 - Many organisms have developed defences to avoid predation by species at higher trophic levels. The capability of primary producers to defend themselves against herbivores affects their own survival, can modulate the strength of trophic cascades and changes rates of competitive exclusion in aquatic communities. Algal species are highly flexible in their morphology, growth form, biochemical composition and production of toxic and deterrent compounds. Several of these variable traits in phytoplankton have been interpreted as defence mechanisms against grazing. Zooplankton feed with differing success on various phytoplankton species, depending primarily on size, shape, cell wall structure and the production of toxins and deterrents. Chemical cues associated with (i) mechanical damage, (ii) herbivore presence and (iii) grazing are the main factors triggering induced defences in both marine and freshwater phytoplankton, but most studies have failed to disentangle the exact mechanism(s) governing defence induction in any particular species. Induced defences in phytoplankton include changes in morphology (e.g. the formation of spines, colonies and thicker cell walls), biochemistry (such as production of toxins, repellents) and in life history characteristics (formation of cysts, reduced recruitment rate). Our categorization of inducible defences in terms of the responsible induction mechanism provides guidance for future work, as hardly any of the available studies on marine or freshwater plankton have performed all the treatments that are required to pinpoint the actual cue(s) for induction. We discuss the ecology of inducible defences in marine and freshwater phytoplankton with a special focus on the mechanisms of induction, the types of defences, their costs and benefits, and their consequences at the community level. KW - Defenses KW - Algae KW - Review KW - Plankton community KW - Cyanobacteria KW - Toxins Y1 - 2011 U6 - https://doi.org/10.1007/s10750-010-0395-4 SN - 0018-8158 SN - 1573-5117 VL - 668 IS - 1 SP - 3 EP - 19 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - van der Lubbe, H. J. L. A1 - Krause-Nehring, J. A1 - Junginger, A. A1 - Garcin, Yannick A1 - Joordens, J. C. A. A1 - Davies, G. R. A1 - Beck, C. A1 - Feibel, C. S. A1 - Johnson, T. C. A1 - Vonhof, H. B. T1 - Gradual or abrupt? Changes in water source of Lake Turkana (Kenya) during the African Humid Period inferred from Sr isotope ratios JF - Quaternary science reviews : the international multidisciplinary research and review journal Y1 - 2017 U6 - https://doi.org/10.1016/j.quascirev.2017.08.010 SN - 0277-3791 VL - 174 SP - 1 EP - 12 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - van der Kroef, Ilona A1 - Koszinski, Sylvia A1 - Grinat, Michael A1 - van der Meij, Marijn W. A1 - Hierold, Wilfried A1 - Südekum, Wolfgang A1 - Sommer, Michael T1 - Digital mapping of buried soil horizons using 2D and pseudo-3D geoelectrical measurements in a ground moraine landscape JF - European journal of soil science : EJSS N2 - The identification of buried soil horizons in agricultural landscapes helps to quantify sediment budgets and erosion-related carbon dynamics. High-resolution mapping of buried horizons using conventional soil surveys is destructive and time consuming. Geoelectrical sensors can offer a fast and non-destructive alternative for determining horizon positions and properties. In this paper, we compare the suitability of several geoelectrical methods for measuring the depth to buried horizons (Apb, Ahb and Hab) in the hummocky ground moraine landscape of northeastern Germany. Soil profile descriptions were developed for 269 locations within a 6-ha experimental field "CarboZALF-D". A stepwise linear discriminant analysis (LDA) estimated the lateral position of the buried horizons using electromagnetic induction data and terrain attributes. To predict the depth of a buried horizon, multiple linear regression (MLR) was used for both a 120-m transect and a 0.2-ha pseudo-three-dimensional (3D) area. At these scales, apparent electrical conductivity (ECa), electrical resistivity (ER) and terrain attributes were used as independent variables. The LDA accurately predicted Apb- and Ahb-horizons (a correct classification of 93%). The LDA of the Hab-horizon had a misclassification of 24%, which was probably related to the smaller test set and the higher depth of this horizon. The MLR predicted the depth of the Apb-, Ahb- and Hab-horizons with relative root mean square errors (RMSEs) of 7, 3 and 13%, respectively, in the pseudo-3D area. MLR had a lower accuracy for the 2D transect compared to the pseudo-3D area. Overall, the use of LDA and MLR has been an efficient methodological approach for predicting buried horizon positions. Highlights The suitability of geoelectrical measurements for digital modelling of diagnostic buried soil horizons was determined. LDA and MLR were used to detect multiple horizons with geoelectrical devices and terrain attributes. Geoelectrical variables were significant predictors of the position of the target soil horizons. The use of these tested digital technologies gives an opportunity to develop high-resolution soil mapping procedures. KW - colluvium depth modelling KW - electrical conductivity KW - electrical resistivity tomography KW - electromagnetic induction KW - EM38DD KW - linear discriminant analysis KW - linear regression KW - moraine soil landscape Y1 - 2019 SN - 1351-0754 SN - 1365-2389 VL - 71 IS - 1 SP - 10 EP - 26 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - van de Vijver, Ruben T1 - Pisoni, D., Remez, R. (eds.), The handbook of speech perception; Oxford, Blackwell, 2005 BT - The handbook of speech perception Y1 - 2009 UR - http://journals.cambridge.org/jid_IPA U6 - https://doi.org/10.1017/S002510030800371x SN - 0025-1003 ER - TY - JOUR A1 - Unuabonah, Emmanuel Iyayi A1 - Taubert, Andreas T1 - Clay-polymer nanocomposites (CPNs): Adsorbents of the future for water treatment JF - Applied clay science : an international journal on the application and technology of clays and clay minerals N2 - A class of adsorbents currently receiving growing attention is the clay-polymer nanocomposite (CPN) adsorbents. CPNs effectively treat water by adsorption and flocculation of both inorganic and organic micropollutants from aqueous solutions. Some of these CPNs - when modified with biocides - also have the ability to efficiently remove microorganisms such as Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans from water. CPNs are far more easily recovered from aqueous media than neat clay. They also exhibit far better treatment times than either polymer or clay adsorbents. They have higher adsorption capacity and better life cycles compared with clay alone. CPNs therefore show an excellent potential as highly efficient water and waste treatment agents. This article reviews the various CPNs that have been prepared recently and used as adsorbents in the removal of micropollutants (inorganic, organic and biological) from aqueous solutions. A special focus is placed on CPNs that are not only interesting from an academic point of view but also effectively reduce the concentration of micropollutants in water to safe limits and also on new developments bordering on CPN use as water treatment agent that have not yet realized their full potential. (C) 2014 Elsevier B.V. All rights reserved. KW - Clay-polymer nanocomposite - CPN KW - Micropollutants KW - Adsorbent KW - Water treatment KW - Microorganism KW - Desorption Y1 - 2014 U6 - https://doi.org/10.1016/j.clay.2014.06.016 SN - 0169-1317 SN - 1872-9053 VL - 99 SP - 83 EP - 92 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Uestuen, Suayib A1 - Börnke, Frederik T1 - Interactions of Xanthomonas type-III effector proteins with the plant ubiquitin and ubiquitin-like pathways JF - Frontiers in plant science N2 - In eukaryotes, regulated protein turnover is required during many cellular processes, including defense against pathogens. Ubiquitination and degradation of ubiquitinated proteins via the ubiquitin proteasome system (UPS) is the main pathway for the turnover of intracellular proteins in eukaryotes. The extensive utilization of the UPS in host cells makes it an ideal pivot for the manipulation of cellular processes by pathogens. Like many other Gram-negative bacteria, Xanthomonas species secrete a suite of type-III effector proteins (T3Es) into their host cells to promote virulence. Some of these T3Es exploit the plant UPS to interfere with immunity. This review summarizes T3E examples from the genus Xanthomonas with a proven or suggested interaction with the host UPS or UPS-like systems and also discusses the apparent paradox that arises from the presence of T3Es that inhibit the UPS in general while others rely on its activity for their function. KW - Xanthomonas KW - type-III effector KW - ubiquitin KW - proteasome KW - plant defense Y1 - 2014 U6 - https://doi.org/10.3389/fpls.2014.00736 SN - 1664-462X VL - 5 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Turner, Bryan S. T1 - Rezension zu: DeHanas, Daniel Nilsson: London Youth, Religion, and Politics: Engagement and Activism from Brixton to Brick Lane. - Oxford : Oxford University Press, 2016. - ISBN: 978-019874367-5 JF - The British Journal of Sociology Y1 - 2018 U6 - https://doi.org/10.1111/1468-4446.12361 SN - 0007-1315 SN - 1468-4446 VL - 69 IS - 3 SP - 876 EP - 877 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Turner, Bryan S. T1 - Time, Science and the Critique of Technological Reason: Essays in Honor of Herminio Martins JF - European Journal of Social Theory Y1 - 2019 U6 - https://doi.org/10.1177/1368431018824454 SN - 1368-4310 SN - 1461-7137 VL - 22 IS - 4 SP - 571 EP - 574 PB - Sage Publ. CY - London ER - TY - JOUR A1 - Turner, Bryan S. T1 - Islam, gender, and democracy in comparative perspective JF - Journal of Religious and Political Practice Y1 - 2018 U6 - https://doi.org/10.1080/20566093.2018.1439439 SN - 2056-6093 SN - 2056-6107 VL - 4 IS - 2 SP - 195 EP - 201 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Turner, Bryan S. T1 - Book review: Populism in the civil sphere / edited: Jeffrey C. Alexander, Peter Kivisto, Giuseppe Sciortino. - Cambridge ; Medford : Polity, 2021. - ISBN 978-1-5095-4474-5 ; 978-1-5095-4473-8 JF - Journal of classical sociology : JCS Y1 - 2021 U6 - https://doi.org/10.1177/1468795X21996104 SN - 1468-795X SN - 1741-2897 VL - 21 IS - 3-4 SP - 357 EP - 360 PB - Sage Publ. CY - London ER - TY - JOUR A1 - Trukenbrod, Hans Arne A1 - Engbert, Ralf T1 - ICAT: a computational model for the adaptive control of fixation durations JF - Psychonomic bulletin & review : a journal of the Psychonomic Society N2 - Eye movements depend on cognitive processes related to visual information processing. Much has been learned about the spatial selection of fixation locations, while the principles governing the temporal control (fixation durations) are less clear. Here, we review current theories for the control of fixation durations in tasks like visual search, scanning, scene perception, and reading and propose a new model for the control of fixation durations. We distinguish two local principles from one global principle of control. First, an autonomous saccade timer initiates saccades after random time intervals (local-I). Second, foveal inhibition permits immediate prolongation of fixation durations by ongoing processing (local-II). Third, saccade timing is adaptive, so that the mean timer value depends on task requirements and fixation history (Global). We demonstrate by numerical simulations that our model qualitatively reproduces patterns of mean fixation durations and fixation duration distributions observed in typical experiments. When combined with assumptions of saccade target selection and oculomotor control, the model accounts for both temporal and spatial aspects of eye movement control in two versions of a visual search task. We conclude that the model provides a promising framework for the control of fixation durations in saccadic tasks. KW - Computational modeling KW - Eye movements KW - Adaptive control KW - Fixation duration Y1 - 2014 U6 - https://doi.org/10.3758/s13423-013-0575-0 SN - 1069-9384 SN - 1531-5320 VL - 21 IS - 4 SP - 907 EP - 934 PB - Springer CY - New York ER - TY - JOUR A1 - Troppmann, Britta A1 - Balfanz, Sabine A1 - Krach, Christian A1 - Baumann, Arnd A1 - Blenau, Wolfgang T1 - Characterization of an Invertebrate-Type Dopamine Receptor of the American Cockroach, Periplaneta americana JF - International journal of molecular sciences N2 - We have isolated a cDNA coding for a putative invertebrate-type dopamine receptor (Peadop2) from P. americana brain by using a PCR-based strategy. The mRNA is present in samples from brain and salivary glands. We analyzed the distribution of the PeaDOP2 receptor protein with specific affinity-purified polyclonal antibodies. On Western blots, PeaDOP2 was detected in protein samples from brain, subesophageal ganglion, thoracic ganglia, and salivary glands. In immunocytochemical experiments, we detected PeaDOP2 in neurons with their somata being located at the anterior edge of the medulla bilaterally innervating the optic lobes and projecting to the ventro-lateral protocerebrum. In order to determine the functional and pharmacological properties of the cloned receptor, we generated a cell line constitutively expressing PeaDOP2. Activation of PeaDOP2-expressing cells with dopamine induced an increase in intracellular cAMP. In contrast, a C-terminally truncated splice variant of this receptor did not exhibit any functional property by itself. The molecular and pharmacological characterization of the first dopamine receptor from P. americana provides the basis for forthcoming studies focusing on the significance of the dopaminergic system in cockroach behavior and physiology. KW - G-protein-coupled receptor KW - dopamine KW - insect KW - cellular signaling KW - salivary gland KW - biogenic amine Y1 - 2014 U6 - https://doi.org/10.3390/ijms15010629 SN - 1422-0067 VL - 15 IS - 1 SP - 629 EP - 653 PB - MDPI CY - Basel ER - TY - JOUR A1 - Tristram, Hildegard L. C. T1 - Thompson, R., Filipino English and Taglish : language switching from multiple perpectives; Amsterdam, John Benjamins Pub, 2003 BT - Filipino English and Taglish : language switching from multiple perpectives N2 - The language situation in the Philipines between the many different native languages and English is complex. The book under review outlines the various contact situations, focussing on the contact between Tagalog, the most important indigenous language of the Philipines on the one hand and English on the other. This serves as the basis for a detailed discussion of the sociological determinasts of the contact continuum between Tagalog on the one hand and Standard English on the other. The main asset of the book is to be found in its well informed survey character resulting from personal teaching experience. Y1 - 2005 ER - TY - JOUR A1 - Tristram, Hildegard L. C. T1 - Kortmann, B. (Hrsg.), Dialectology meets typology : dialect grammar from a cross-linguistic perspective; Berlin, Mouton de Gruyter, 2004 BT - Dialectology meets typology : dialect grammar from a cross-linguistic perspective N2 - In previous research, the methodology of typological investigations into languages was based on the analysis of standard languages (or rather standardised written languages). Prof. Kortmann's collection of essays broadens this methodological scope by directing the scholars' typological interest to the traditional dialects, most of them transmitted orally only. Undoubtedly, there is a great potential in this effort. Most of the contributions in this volume, however, show, that the attempt to unify or perhaps rather to accommodate the methodologies of typological research and traditional dialectology needs to be further harmonised in future research in order to bear sound generalisable insights to the rich data available. Y1 - 2005 ER - TY - JOUR A1 - Tillack-Graf, Anne-Kathleen T1 - Nurses and Midwives in Nazi Germany: The "Euthanasia Programs" JF - Social history of medicine : the journal of the Society for the Social History of Medicine Y1 - 2015 U6 - https://doi.org/10.1093/shm/hkv027 SN - 0951-631X SN - 1477-4666 VL - 28 IS - 2 SP - 413 EP - 415 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Tillack-Graf, Anne-Kathleen T1 - Madness and Sense BT - Patients, Doctors, Personnel and institutions of Psychiatry in Saxony from the Middle Ages until the End of the 20th Century JF - History of psychiatry Y1 - 2015 U6 - https://doi.org/10.1177/0957154X15605782d SN - 0957-154X SN - 1740-2360 VL - 26 IS - 4 SP - 498 EP - 499 PB - Sage Publ. CY - London ER - TY - JOUR A1 - Tian, Mei A1 - Reichetzeder, Christoph A1 - Li, Jian A1 - Hocher, Berthold T1 - Low birth weight, a risk factor for diseases in later life, is a surrogate of insulin resistance at birth JF - Journal of hypertension N2 - Low birth weight (LBW) is associated with diseases in adulthood. The birthweight attributed risk is independent of confounding such as gestational age, sex of the newborn but also social factors. The birthweight attributed risk for diseases in later life holds for the whole spectrum of birthweight. This raises the question what pathophysiological principle is actually behind the association. In this review, we provide evidence that LBW is a surrogate of insulin resistance. Insulin resistance has been identified as a key factor leading to type 2 diabetes, cardiovascular disease as well as kidney diseases. We first provide evidence linking LBW to insulin resistance during intrauterine life. This might be caused by both genetic (genetic variations of genes controlling glucose homeostasis) and/or environmental factors (due to alterations of macronutrition and micronutrition of the mother during pregnancy, but also effects of paternal nutrition prior to conception) leading via epigenetic modifications to early life insulin resistance and alterations of intrauterine growth, as insulin is a growth factor in early life. LBW is rather a surrogate of insulin resistance in early life - either due to inborn genetic or environmental reasons - rather than a player on its own. KW - epigenetics KW - fetal programing KW - genetics KW - insulin resistance KW - low birth weight Y1 - 2019 U6 - https://doi.org/10.1097/HJH.0000000000002156 SN - 0263-6352 SN - 1473-5598 VL - 37 IS - 11 SP - 2123 EP - 2134 PB - Kluwer CY - Philadelphia ER - TY - JOUR A1 - Thieken, Annegret A1 - Kienzler, Sarah A1 - Kreibich, Heidi A1 - Kuhlicke, Christian A1 - Kunz, Michael A1 - Muehr, Bernhard A1 - Mueller, Meike A1 - Otto, Antje A1 - Petrow, Theresia A1 - Pisi, Sebastian A1 - Schroeter, Kai T1 - Review of the flood risk management system in Germany after the major flood in 2013 JF - Ecology and society : a journal of integrative science for resilience and sustainability N2 - Widespread flooding in June 2013 caused damage costs of (sic)6 to 8 billion in Germany, and awoke many memories of the floods in August 2002, which resulted in total damage of (sic)11.6 billion and hence was the most expensive natural hazard event in Germany up to now. The event of 2002 does, however, also mark a reorientation toward an integrated flood risk management system in Germany. Therefore, the flood of 2013 offered the opportunity to review how the measures that politics, administration, and civil society have implemented since 2002 helped to cope with the flood and what still needs to be done to achieve effective and more integrated flood risk management. The review highlights considerable improvements on many levels, in particular (1) an increased consideration of flood hazards in spatial planning and urban development, (2) comprehensive property-level mitigation and preparedness measures, (3) more effective flood warnings and improved coordination of disaster response, and (4) a more targeted maintenance of flood defense systems. In 2013, this led to more effective flood management and to a reduction of damage. Nevertheless, important aspects remain unclear and need to be clarified. This particularly holds for balanced and coordinated strategies for reducing and overcoming the impacts of flooding in large catchments, cross-border and interdisciplinary cooperation, the role of the general public in the different phases of flood risk management, as well as a transparent risk transfer system. Recurring flood events reveal that flood risk management is a continuous task. Hence, risk drivers, such as climate change, land-use changes, economic developments, or demographic change and the resultant risks must be investigated at regular intervals, and risk reduction strategies and processes must be reassessed as well as adapted and implemented in a dialogue with all stakeholders. KW - August 2002 flood KW - Central Europe KW - Floods Directive KW - governance KW - June 2013 flood KW - risk management cycle Y1 - 2016 U6 - https://doi.org/10.5751/ES-08547-210251 SN - 1708-3087 VL - 21 SP - 8612 EP - 8614 PB - Resilience Alliance CY - Wolfville ER - TY - JOUR A1 - Terao, Mineko A1 - Romao, Maria Joao A1 - Leimkühler, Silke A1 - Bolis, Marco A1 - Fratelli, Maddalena A1 - Coelho, Catarina A1 - Santos-Silva, Teresa A1 - Garattini, Enrico T1 - Structure and function of mammalian aldehyde oxidases JF - Archives of toxicology : official journal of EUROTOX N2 - Mammalian aldehyde oxidases (AOXs; EC1.2.3.1) are a group of conserved proteins belonging to the family of molybdo-flavoenzymes along with the structurally related xanthine dehydrogenase enzyme. AOXs are characterized by broad substrate specificity, oxidizing not only aromatic and aliphatic aldehydes into the corresponding carboxylic acids, but also hydroxylating a series of heteroaromatic rings. The number of AOX isoenzymes expressed in different vertebrate species is variable. The two extremes are represented by humans, which express a single enzyme (AOX1) in many organs and mice or rats which are characterized by tissue-specific expression of four isoforms (AOX1, AOX2, AOX3, and AOX4). In vertebrates each AOX isoenzyme is the product of a distinct gene consisting of 35 highly conserved exons. The extant species-specific complement of AOX isoenzymes is the result of a complex evolutionary process consisting of a first phase characterized by a series of asynchronous gene duplications and a second phase where the pseudogenization and gene deletion events prevail. In the last few years remarkable advances in the elucidation of the structural characteristics and the catalytic mechanisms of mammalian AOXs have been made thanks to the successful crystallization of human AOX1 and mouse AOX3. Much less is known about the physiological function and physiological substrates of human AOX1 and other mammalian AOX isoenzymes, although the importance of these proteins in xenobiotic metabolism is fairly well established and their relevance in drug development is increasing. This review article provides an overview and a discussion of the current knowledge on mammalian AOX. KW - Aldehyde oxidase KW - Molybdo-flavoenzymes KW - Xanthine oxidoreductase KW - Drug metabolism Y1 - 2016 U6 - https://doi.org/10.1007/s00204-016-1683-1 SN - 0340-5761 SN - 1432-0738 VL - 90 SP - 753 EP - 780 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Temmen, Jens T1 - The Unsettlement of America: Translation, Interpretation, and the Story of Don Luis de Velasco, 1560-1945 JF - Zeitschrift für Anglistik und Amerikanistik : a quarterly of language, literature and cultur Y1 - 2017 U6 - https://doi.org/10.1515/zaa-2017-0011 SN - 0044-2305 SN - 2196-4726 VL - 65 IS - 1 SP - 117 EP - 119 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Taubert, Andreas T1 - Electrospinning of Ionogels: Current Status and Future Perspectives JF - European journal of inorganic chemistry : a journal of ChemPubSoc Europe N2 - Ionogels (IGs), also termed ion gels, are functional hybrid materials based on an ionic liquid (IL) and a polymeric, hybrid, or inorganic matrix. IGs combine the properties of the matrix such as mechanical strength with IL properties like high ionic conductivity, high thermal stability, or catalytic activity. IGs are thus attractive for many applications, but the vast majority of IGs made and published so far are bulk materials or dense films. Applications like sensing or catalysis, however, would benefit from IGs with high surface areas or defined surface morphologies or architectures. In spite of this, only relatively few examples of high-surface-area IGs have been made so far; this has mostly been achieved by electrospinning, which has proven to be a promising strategy towards advanced IGs. The current review discusses first developments and outlines the future potential of electrospun ionogels, predominantly from a materials and inorganic chemistry perspective. KW - Ionic liquids KW - Ionogels KW - Hybrid materials KW - Electrospinning KW - Heterogeneous catalysis KW - Sensors KW - Energy KW - Health Y1 - 2015 U6 - https://doi.org/10.1002/ejic.201402490 SN - 1434-1948 SN - 1099-0682 IS - 7 SP - 1148 EP - 1159 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Tarasova, Larisa A1 - Merz, Ralf A1 - Kiss, Andrea A1 - Basso, Stefano A1 - Blöchl, Günter A1 - Merz, Bruno A1 - Viglione, Alberto A1 - Plötner, Stefan A1 - Guse, Björn A1 - Schumann, Andreas A1 - Fischer, Svenja A1 - Ahrens, Bodo A1 - Anwar, Faizan A1 - Bárdossy, András A1 - Bühler, Philipp A1 - Haberlandt, Uwe A1 - Kreibich, Heidi A1 - Krug, Amelie A1 - Lun, David A1 - Müller-Thomy, Hannes A1 - Pidoto, Ross A1 - Primo, Cristina A1 - Seidel, Jochen A1 - Vorogushyn, Sergiy A1 - Wietzke, Luzie T1 - Causative classification of river flood events JF - Wiley Interdisciplinary Reviews : Water N2 - A wide variety of processes controls the time of occurrence, duration, extent, and severity of river floods. Classifying flood events by their causative processes may assist in enhancing the accuracy of local and regional flood frequency estimates and support the detection and interpretation of any changes in flood occurrence and magnitudes. This paper provides a critical review of existing causative classifications of instrumental and preinstrumental series of flood events, discusses their validity and applications, and identifies opportunities for moving toward more comprehensive approaches. So far no unified definition of causative mechanisms of flood events exists. Existing frameworks for classification of instrumental and preinstrumental series of flood events adopt different perspectives: hydroclimatic (large-scale circulation patterns and atmospheric state at the time of the event), hydrological (catchment scale precipitation patterns and antecedent catchment state), and hydrograph-based (indirectly considering generating mechanisms through their effects on hydrograph characteristics). All of these approaches intend to capture the flood generating mechanisms and are useful for characterizing the flood processes at various spatial and temporal scales. However, uncertainty analyses with respect to indicators, classification methods, and data to assess the robustness of the classification are rarely performed which limits the transferability across different geographic regions. It is argued that more rigorous testing is needed. There are opportunities for extending classification methods to include indicators of space-time dynamics of rainfall, antecedent wetness, and routing effects, which will make the classification schemes even more useful for understanding and estimating floods. This article is categorized under: Science of Water > Water Extremes Science of Water > Hydrological Processes Science of Water > Methods KW - flood genesis KW - flood mechanisms KW - flood typology KW - historical floods KW - hydroclimatology of floods Y1 - 2019 U6 - https://doi.org/10.1002/wat2.1353 SN - 2049-1948 VL - 6 IS - 4 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Tang, Kam W. A1 - McGinnis, Daniel F. A1 - Ionescu, Danny A1 - Großart, Hans-Peter T1 - Methane Production in Oxic Lake Waters Potentially Increases Aquatic Methane Flux to Air JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - Active methane production in oxygenated lake waters challenges the long-standing paradigm that microbial methane production occurs only under anoxic conditions and forces us to rethink the ecology and environmental dynamics of this powerful greenhouse gas. Methane production in the upper oxic water layers places the methane source closer to the air water interface, where convective mixing and microbubble detrainment can lead to a methane efflux higher than that previously assumed. Microorganisms may produce methane in oxic environments by being equipped with enzymes to counteract the effects of molecular oxygen during methanogenesis or using alternative pathways that do not involve oxygen-sensitive enzymes. As this process appears to be influenced by thermal stratification, water transparency, and primary production, changes in lake ecology due to climate change will alter methane formation in oxic water layers, with far-reaching consequences for methane flux and climate feedback. Y1 - 2016 U6 - https://doi.org/10.1021/acs.estlett.6b00150 SN - 2328-8930 VL - 3 SP - 227 EP - 233 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Tang, Kam W. A1 - Gladyshev, Michail I. A1 - Dubovskaya, Olga P. A1 - Kirillin, Georgiy A1 - Grossart, Hans-Peter T1 - Zooplankton carcasses and non-predatory mortality in freshwater and inland sea environments JF - Journal of plankton research N2 - Zooplankton carcasses are ubiquitous in marine and freshwater systems, implicating the importance of non-predatory mortality, but both are often overlooked in ecological studies compared with predatory mortality. The development of several microscopic methods allows the distinction between live and dead zooplankton in field samples, and the reported percentages of dead zooplankton average 11.6 (minimum) to 59.8 (maximum) in marine environments, and 7.4 (minimum) to 47.6 (maximum) in fresh and inland waters. Common causes of non-predatory mortality among zooplankton include senescence, temperature change, physical and chemical stresses, parasitism and food-related factors. Carcasses resulting from non-predatory mortality may undergo decomposition leading to an increase in microbial production and a shift in microbial composition in the water column. Alternatively, sinking carcasses may contribute significantly to vertical carbon flux especially outside the phytoplankton growth seasons, and become a food source for the benthos. Global climate change is already altering freshwater ecosystems on multiple levels, and likely will have significant positive or negative effects on zooplankton non-predatory mortality. Better spatial and temporal studies of zooplankton carcasses and non-predatory mortality rates will improve our understanding of this important but under-appreciated topic. KW - carbon flux KW - inland waters KW - lakes KW - live KW - dead sorting KW - non-predatory mortality KW - zooplankton carcasses Y1 - 2014 U6 - https://doi.org/10.1093/plankt/fbu014 SN - 0142-7873 SN - 1464-3774 VL - 36 IS - 3 SP - 597 EP - 612 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Szaramowicz, Martin T1 - Krönert, R. (Hrsg.): Landscape Balance and Landscape Assessment; Berlin, Springer, 2001 BT - Landscape Balance and Landscape Assessment Y1 - 2002 ER - TY - JOUR A1 - Szalay, J. R. A1 - Poppe, A. R. A1 - Agarwal, J. A1 - Britt, D. A1 - Belskaya, I. A1 - Horanyi, M. A1 - Nakamura, T. A1 - Sachse, M. A1 - Spahn, Frank T1 - Dust Phenomena Relating to Airless Bodies JF - Space science reviews N2 - Airless bodies are directly exposed to ambient plasma and meteoroid fluxes, making them characteristically different from bodies whose dense atmospheres protect their surfaces from such fluxes. Direct exposure to plasma and meteoroids has important consequences for the formation and evolution of planetary surfaces, including altering chemical makeup and optical properties, generating neutral gas and/or dust exospheres, and leading to the generation of circumplanetary and interplanetary dust grain populations. In the past two decades, there have been many advancements in our understanding of airless bodies and their interaction with various dust populations. In this paper, we describe relevant dust phenomena on the surface and in the vicinity of airless bodies over a broad range of scale sizes from to , with a focus on recent developments in this field. KW - Dust KW - Airless bodies KW - Interplanetary dust Y1 - 2018 U6 - https://doi.org/10.1007/s11214-018-0527-0 SN - 0038-6308 SN - 1572-9672 VL - 214 IS - 5 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Syed, Moin A1 - Juang, Linda P. A1 - Svensson, Ylva T1 - Toward a new understanding of ethnic-racial settings for ethnic-racial identity development JF - Journal of research on adolescence : the official journal of the Society for Research on Adolescence N2 - The purpose of this conceptual article is to advance theory and research on one critical aspect of the context of ethnic–racial identity (ERI) development: ethnic–racial settings, or the objective and subjective nature of group representation within an individual's context. We present a new conceptual framework that consists of four dimensions: (1) perspective (that settings can be understood in both objective and subjective terms); (2) differentiation (how groups are defined in a setting); (3) heterogeneity (the range of groups in a setting); and (4) proximity (the distance between the individual and the setting). Clarifying this complexity is crucial for advancing a more coherent understanding of how ethnic–racial settings are related to ERI development. Y1 - 2018 U6 - https://doi.org/10.1111/jora.12387 SN - 1050-8392 SN - 1532-7795 VL - 28 IS - 2 SP - 262 EP - 276 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Suriyanarayanan, Subramanian A1 - Cywinski, Piotr J. A1 - Moro, Artur J. A1 - Mohr, Gerhard J. A1 - Kutner, Wlodzimierz ED - Haupt, K T1 - Chemosensors based on molecularly imprinted polymers JF - Topics in current chemistry JF - Topics in Current Chemistry Y1 - 2012 SN - 978-3-642-28421-2 U6 - https://doi.org/10.1007/128_2010_92 SN - 0340-1022 VL - 325 IS - 4 SP - 165 EP - 265 PB - Springer CY - Berlin ER - TY - JOUR A1 - Subetto, D. A. A1 - Nazarova, Larisa B. A1 - Pestryakova, Luidmila Agafyevna A1 - Syrykh, Liudmila A1 - Andronikov, A. V. A1 - Biskaborn, Boris A1 - Diekmann, Bernhard A1 - Kuznetsov, D. D. A1 - Sapelko, T. V. A1 - Grekov, I. M. T1 - Paleolimnological studies in Russian northern Eurasia BT - a review JF - Contemporary Problems of Ecology N2 - This article presents a review of the current data on the level of paleolimnological knowledge about lakes in the Russian part of the northern Eurasia. The results of investigation of the northwestern European part of Russia as the best paleolimnologically studied sector of the Russian north is presented in detail. The conditions of lacustrine sedimentation at the boundary between the Late Pleistocene and Holocene and the role of different external factors in formation of their chemical composition, including active volcanic activity and possible large meteorite impacts, are also discussed. The results of major paleoclimatic and paleoecological reconstructions in northern Siberia are presented. Particular attention is given to the databases of abiotic and biotic parameters of lake ecosystems as an important basis for quantitative reconstructions of climatic and ecological changes in the Late Pleistocene and Holocene. Keywords: paleolimnology, lakes, bottom sediments, northern. KW - paleolimnology KW - lakes KW - bottom sediments KW - northern Eurasia KW - Russian Arctic KW - databases Y1 - 2017 U6 - https://doi.org/10.1134/S1995425517040102 SN - 1995-4255 SN - 1995-4263 VL - 10 SP - 327 EP - 335 PB - Pleiades Publ. CY - New York ER - TY - JOUR A1 - Stölting, Erhard T1 - Jones, L. E. (Hrsg.), Reform, reaction and resistance, studies in the history of german conservatism from 1789 to 1945; Oxford, Berg, 1993 BT - Reform, reaction and resistance : studies in the history of german conservatism from 1789 to 1945 Y1 - 1996 ER - TY - JOUR A1 - Stölting, Erhard T1 - Muller, J. Z., The other god that failed, Hans Freyer and the Deradicalization of German Conservatism; Princeton, N.J., Princeton Univ. Press, 1987 BT - The other god that failed : Hans Freyer and the Deradicalization of German Conservatism Y1 - 1993 ER - TY - JOUR A1 - Stockhorst, Stefanie T1 - Taberner, S. (Hrsg.), Cooke, P. (Hrsg.), German culture, politics, and literature into the twenty-first century: beyond normalization; Rochester, Camden, 2006 BT - German culture, politics, and literature into the twenty-first century: beyond normalization Y1 - 2007 ER -