TY  - JOUR
A1  - Wippert, Pia-Maria
A1  - Wiebking, C.
T1  - Adaptation to physical activity and mental stress in the context of pain. Psychobiological aspects
JF  - Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der Österreichischen Schmerzgesellschaft und der Deutschen Interdisziplinären Vereinigung für Schmerztherapie
N2  - The genesis of chronic pain is predominantly explained by a multidimensional pain model approach that is based on the dysfunctional influence of biological, psychological and social variables as key risk factors inducing aberrant long-term changes. Biological facets comprise adaptation processes on the neuronal, musculoskeletal and (psycho) biological level that can be influenced by physical training or psychosocial factors, such as stress. These factors can play a causative role in developing dysfunctional adaptation mechanisms, which in turn prepare the biological ground to facilitate negative long-term changes in the peripheral and central nervous systems. Hence, these processes can be assumed to be fundamentally involved in the transition from acute to chronic and persistent pain. The aim of this review article is to discuss hypotheses for the genesis of chronic pain and possible treatment strategies. Selected research results about maladaptive processes in chronic pain due to psychological stress and physical activity are presented in order to inspire discussions about the ideal dose-response relationship of physical activity and the combination of different therapeutic concepts.
KW  - Chronic pain
KW  - Neuronal plasticity
KW  - Pain management
KW  - Central nervous system
KW  - Peripheral nervous system
Y1  - 2016
U6  - https://doi.org/10.1007/s00482-016-0147-0
SN  - 0932-433X
SN  - 1432-2129
VL  - 30
SP  - 429
EP  - 436
PB  - Springer
CY  - New York
ER  -