TY  - JOUR
A1  - Kiefer, Thomas
A1  - Krahl, Dorothea
A1  - Hirt, Carsten
A1  - Völler, Heinz
A1  - Voelkel, Lorenz
A1  - Daeschlein, Georg
T1  - Influence of treatment caused impairments on anxiety and depression in patients with cancer of the Esophagus or the Esophagogastric junction
JF  - Journal of gastrointestinal cancer
N2  - Purpose
After therapy of cancer of the esophagus or the esophagogastric junction, patients often suffer from anxiety and depression. Some risk factors for elevated anxiety and depression are reported, but the influence of steatorrhea, the frequency of which has only recently been reported, has not yet been investigated. 

Method
Using the Hospital Anxiety and Depression Scale (HADS), we analyzed the correlation of anxiety and depression with steatorrhea, appetite, and weight loss in 72 patients with cancer of the esophagus or of the esophagogastric junction, who were treated at our rehabilitation clinic between January 2011 and December 2014. In addition, effectiveness of psychological interviews was analyzed.

Results
We have evaluable anxiety questionnaires from 51 patients showing a median anxiety value of 5 (range 0-13). As for the depression, results from evaluable questionnaires of 54 patients also showed a median value of 5 (range 0-15). Increased anxiety and depression values (> 7) were observed in 25.4% and 37.0% of the patients respectively. Patients who were admitted with steatorrhea for rehabilitation showed a statistically higher anxiety value (median 6.3 vs. 4.7, p < 0.05), reduced appetite, and a weight loss above 15 kg depicting a correlation to anxiety and depression. Psychological conversations helped lowering the depression but had no influence on anxiety. 

Conclusions
Impairments after cancer treatment, such as steatorrhea, appetite loss, and weight loss, should be interpreted as an alarm signal and should necessitate screening for increased anxiety and depression. Psychological therapy can help improving the extent of the depression.
KW  - Anxiety
KW  - Depression
KW  - Esophagus carcinoma
KW  - Exocrine pancreas
KW  - insufficiency
KW  - Rehabilitation
KW  - Steatorrhea
Y1  - 2019
U6  - https://doi.org/10.1007/s12029-018-00193-7
SN  - 1941-6628
SN  - 1941-6636
VL  - 51
IS  - 1
SP  - 30
EP  - 34
PB  - Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Heissel, Andreas
A1  - Zech, Philipp
A1  - Rapp, Michael A.
A1  - Schuch, Felipe B.
A1  - Lawrence, Jimmy B.
A1  - Kangas, Maria
A1  - Heinzel, Stephan
T1  - Effects of exercise on depression and anxiety in persons living with HIV: A meta-analysis
JF  - Journal of psychosomatic research
N2  - Objective: The purpose of this systematic review and meta-analysis was to examine the effects of exercise on depression and anxiety in people living with HIV (PLWH), and to evaluate, through subgroup analysis, the effects of exercise type, frequency, supervision by exercise professionals, study quality, and control group conditions on these outcomes. Method: A literature search was conducted through four electronic databases from inception to February 2019. Considered for inclusion were randomized controlled trials (RCTs) investigating exercise interventions and depression or anxiety as outcomes in people living with HIV (>= 18 years of age). Ten studies were included (n = 479 participants, 49.67% females at baseline), and the standardized mean difference (SMD) and heterogeneity were calculated using random-effect models. An additional pre-post meta-analysis was also conducted. Results: A large effect in favor of exercise when compared to controls was found for depression (SMD = -0.84, 95%CI = [-1.57, -0.11], p = 0.02) and anxiety (SMD = -1.23, 95%CI = [-2.42, 0.04], p = -0.04). Subgroup analyses for depression revealed large effects on depression for aerobic exercise only (SMD = -0.96, 95%CI = [-1.63, -0.30], p = 0.004), a frequency of >= 3 exercise sessions per week (SMD = -1.39, 95%CI = [-2.24, -0.54], p < 0.001), professionally supervised exercise (SMD = -1.40, 95%CI = [-2.46, -0.17], p = 0.03]), and high-quality studies (SMD = -1.31, 95%CI = [-2.46, -0.17], p = 0.02). Conclusion: Exercise seems to decrease depressive symptoms and anxiety in PLWH, but other larger and high-quality studies are needed to verify these effects.
KW  - HIV
KW  - Exercise
KW  - Depression
KW  - Anxiety
KW  - Meta-analysis
KW  - Supervision
Y1  - 2019
U6  - https://doi.org/10.1016/j.jpsychores.2019.109823
SN  - 0022-3999
SN  - 1879-1360
VL  - 126
PB  - Elsevier
CY  - Oxford
ER  -