TY  - JOUR
A1  - Amezcua, Javier
A1  - Ide, Kayo
A1  - Kalnay, Eugenia
A1  - Reich, Sebastian
T1  - Ensemble transform Kalman-Bucy filters
JF  - Quarterly journal of the Royal Meteorological Society
N2  - Two recent works have adapted the Kalman-Bucy filter into an ensemble setting. In the first formulation, the ensemble of perturbations is updated by the solution of an ordinary differential equation (ODE) in pseudo-time, while the mean is updated as in the standard Kalman filter. In the second formulation, the full ensemble is updated in the analysis step as the solution of single set of ODEs in pseudo-time. Neither requires matrix inversions except for the frequently diagonal observation error covariance.
 We analyse the behaviour of the ODEs involved in these formulations. We demonstrate that they stiffen for large magnitudes of the ratio of background error to observational error variance, and that using the integration scheme proposed in both formulations can lead to failure. A numerical integration scheme that is both stable and is not computationally expensive is proposed. We develop transform-based alternatives for these Bucy-type approaches so that the integrations are computed in ensemble space where the variables are weights (of dimension equal to the ensemble size) rather than model variables.
 Finally, the performance of our ensemble transform Kalman-Bucy implementations is evaluated using three models: the 3-variable Lorenz 1963 model, the 40-variable Lorenz 1996 model, and a medium complexity atmospheric general circulation model known as SPEEDY. The results from all three models are encouraging and warrant further exploration of these assimilation techniques.
KW  - Kalman-Bucy Filter
KW  - Ensemble Kalman Filter
KW  - stiff ODE
KW  - weight-based formulations
Y1  - 2014
U6  - https://doi.org/10.1002/qj.2186
SN  - 0035-9009
SN  - 1477-870X
VL  - 140
IS  - 680
SP  - 995
EP  - 1004
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - CHAP
A1  - Andersson, H.
A1  - Keunecke, A.
A1  - Eser, A.
A1  - Huisinga, Wilhelm
A1  - Reinisch, W.
A1  - Kloft, Charlotte
T1  - Pharmacokinetic considerations for optimising dosing regimens of  a potsdam univ infliximab in patients with Crohn's disease
T2  - JOURNAL OF CROHNS & COLITIS
Y1  - 2014
U6  - https://doi.org/10.1016/S1873-9946(14)60086-6
SN  - 1873-9946
SN  - 1876-4479
VL  - 8
SP  - S44
EP  - S44
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Antoniewicz, Franziska
A1  - Brand, Ralf
T1  - Automatic evaluations and exercise setting preference in frequent exercisers
JF  - Journal of sport & exercise psychology
N2  - The goals of this study were to test whether exercise-related stimuli can elicit automatic evaluative responses and whether automatic evaluations reflect exercise setting preference in highly active exercisers. An adapted version of the Affect Misattribution Procedure was employed. Seventy-two highly active exercisers (26 years +/- 9.03; 43% female) were subliminally primed (7 ms) with pictures depicting typical fitness center scenarios or gray rectangles (control primes). After each prime, participants consciously evaluated the "pleasantness" of a Chinese symbol. Controlled evaluations were measured with a questionnaire and were more positive in participants who regularly visited fitness centers than in those who reported avoiding this exercise setting. Only center exercisers gave automatic positive evaluations of the fitness center setting (partial eta squared = .08). It is proposed that a subliminal Affect Misattribution Procedure paradigm can detect automatic evaluations to exercising and that, in highly active exercisers, these evaluations play a role in decisions about the exercise setting rather than the amounts of physical exercise. Findings are interpreted in terms of a dual systems theory of social information processing and behavior.
KW  - exercise
KW  - health
KW  - affect misattribution procedure
Y1  - 2014
U6  - https://doi.org/10.1123/jsep.2014-0033
SN  - 0895-2779
SN  - 1543-2904
VL  - 36
IS  - 6
SP  - 631
EP  - 636
PB  - Human Kinetics Publ.
CY  - Champaign
ER  - 
TY  - CHAP
A1  - Appiah-Dwomoh, Edem Korkor
A1  - Torlak, Firdevs
A1  - Engel, Tilman
A1  - Stoll, Josefine
A1  - Müller, Juliane
A1  - Mayer, Frank
T1  - Does perturbed treadmill walking lead to emg-changes of the lower extremity?
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2014
SN  - 0195-9131
SN  - 1530-0315
VL  - 46
IS  - 5
SP  - 827
EP  - 827
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Archambault, S.
A1  - Arlen, T.
A1  - Aune, T.
A1  - Beilicke, M.
A1  - Benbow, W.
A1  - Bird, R.
A1  - Boettcher, Markus
A1  - Bouvier, A.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Ciupik, L.
A1  - Collins-Hughes, E.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Dickherber, R.
A1  - Dumm, J.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Federici, Simone
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Gall, D.
A1  - Garson, A. III.
A1  - Gillanders, G. H.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Gusbar, C.
A1  - Gyuk, G.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Kaaret, P.
A1  - Kertzman, M.
A1  - Khassen, Y.
A1  - Kieda, D.
A1  - Krawczynski, H.
A1  - Lamerato, A.
A1  - Lang, M. J.
A1  - Li, K.
A1  - Madhavan, A. S.
A1  - Maier, G.
A1  - Majumdar, P.
A1  - McArthur, S.
A1  - McCann, A.
A1  - Millis, J.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Orr, M.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Perkins, J. S.
A1  - Pohl, Martin
A1  - Popkow, A.
A1  - Prokoph, H.
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Roustazadeh, P.
A1  - Saxon, D. B.
A1  - Sembroski, G. H.
A1  - Senturk, G. D.
A1  - Skole, C.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Tesic, G.
A1  - Theiling, M.
A1  - Varlotta, A.
A1  - Vassiliev, V. V.
A1  - Vincent, S.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Welsing, R.
A1  - Williams, D. A.
A1  - Zitzer, B.
T1  - Test of models of the cosmic infrared background with multiwavelength  observations of the blazar 1ES 1218+30.4 IN 2009
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We present the results of a multi-wavelength campaign targeting the blazar 1ES 1218+30.4 with observations with the 1.3 m McGraw-Hill optical telescope, the Rossi X-ray Timing Explorer (RXTE), the Fermi Gamma-Ray Space Telescope, and the Very Energetic Radiation Imaging Telescope Array System (VERITAS). The RXTE and VERITAS observations were spread over a 13 day period and revealed clear evidence for flux variability, and a strong X-ray and gamma-ray flare on 2009 February 26 (MJD 54888). The campaign delivered a well-sampled broadband energy spectrum with simultaneous RXTE and VERITAS very high energy (VHE, > 100 GeV) observations, as well as contemporaneous optical and Fermi observations. The 1ES 1218+30.4 broadband energy spectrum-the first with simultaneous X-ray and VHE gamma-ray energy spectra-is of particular interest as the source is located at a high cosmological redshift for a VHE source (z = 0.182), leading to strong absorption of VHE gamma rays by photons from the optical/infrared extragalactic background light (EBL) via gamma VHE +gamma EBL -> e(+) e(-)pair-creation processes. We model the data with a one-zone synchrotron self-Compton (SSC) emission model and with the extragalactic absorption predicted by several recent EBL models. We find that the observations are consistent with the SSC scenario and all the EBL models considered in this work. We discuss observational and theoretical avenues to improve on the EBL constraints.
KW  - BL Lacertae objects: general
KW  - BL Lacertae objects: individual (1ES1218+30.4)
KW  - cosmic background radiation
KW  - diffuse radiation
KW  - galaxies: jets
KW  - gamma rays: galaxies
Y1  - 2014
U6  - https://doi.org/10.1088/0004-637X/788/2/158
SN  - 0004-637X
SN  - 1538-4357
VL  - 788
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Archambault, S.
A1  - Aune, T.
A1  - Behera, B.
A1  - Beilicke, M.
A1  - Benbow, W.
A1  - Berger, K.
A1  - Bird, R.
A1  - Biteau, Jonathan
A1  - Bugaev, V.
A1  - Byrum, K.
A1  - Cardenzana, J. V.
A1  - Cerruti, M.
A1  - Chen, Xuhui
A1  - Ciupik, L.
A1  - Connolly, M. P.
A1  - Cui, Wei
A1  - Dumm, J.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Federici, Simone
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Gillanders, G. H.
A1  - Griffin, S.
A1  - Griffiths, S. T.
A1  - Grube, J.
A1  - Gyuk, G.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kertzman, M.
A1  - Khassen, Y.
A1  - Kieda, D.
A1  - Krawczynski, H.
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Madhavan, A. S.
A1  - Maier, G.
A1  - McCann, A.
A1  - Meagher, K.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nieto, Daniel
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Pohl, Martin
A1  - Popkow, A.
A1  - Prokoph, H.
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Rajotte, J.
A1  - Reyes, L. C.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Sembroski, G. H.
A1  - Shahinyan, K.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Tucci, J. V.
A1  - Tyler, J.
A1  - Varlotta, A.
A1  - Vassiliev, V. V.
A1  - Vincent, S.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Welsing, R.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Ackermann, Margit
A1  - Ajello, M.
A1  - Albert, A.
A1  - Baldini, L.
A1  - Bastieri, D.
A1  - Bellazzini, R.
A1  - Bissaldi, E.
A1  - Bregeon, Johan
A1  - Buehler, R.
A1  - Buson, S.
A1  - Caliandro, G. A.
A1  - Cameron, R. A.
A1  - Caraveo, P. A.
A1  - Cavazzuti, E.
A1  - Charles, E.
A1  - Chiang, J.
A1  - Ciprini, S.
A1  - Claus, R.
A1  - Cutini, S.
A1  - de Angelis, A.
A1  - de Palma, F.
A1  - Dermer, C. D.
A1  - Digel, S. W.
A1  - Di Venere, L.
A1  - Drell, P. S.
A1  - Favuzzi, C.
A1  - Franckowiak, A.
A1  - Fusco, P.
A1  - Gargano, F.
A1  - Gasparrini, D.
A1  - Giglietto, N.
A1  - Giordano, F.
A1  - Giroletti, M.
A1  - Grenier, I. A.
A1  - Guiriec, S.
A1  - Jogler, T.
A1  - Kuss, M.
A1  - Larsson, S.
A1  - Latronico, L.
A1  - Longo, F.
A1  - Loparco, F.
A1  - Lubrano, P.
A1  - Madejski, G. M.
A1  - Mayer, M.
A1  - Mazziotta, Mario Nicola
A1  - Michelson, P. F.
A1  - Mizuno, T.
A1  - Monzani, M. E.
A1  - Morselli, Aldo
A1  - Murgia, S.
A1  - Nuss, E.
A1  - Ohsugi, T.
A1  - Ormes, J. F.
A1  - Paneque, D.
A1  - Perkins, J. S.
A1  - Piron, F.
A1  - Pivato, G.
A1  - Raino, S.
A1  - Razzano, M.
A1  - Reimer, A.
A1  - Reimer, Olaf
A1  - Ritz, S.
A1  - Schaal, M.
A1  - Sgro, C.
A1  - Siskind, E. J.
A1  - Spinelli, P.
A1  - Takahashi, H.
A1  - Tibaldo, L.
A1  - Tinivella, M.
A1  - Troja, E.
A1  - Vianello, G.
A1  - Werner, M.
A1  - Wood, M.
T1  - Deep broadband observations of the distant gamma-ray blazar PKS 1424+240
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters
N2  - We present deep VERITAS observations of the blazar PKS 1424+240, along with contemporaneous Fermi Large Area Telescope, Swift X-ray Telescope, and Swift UV Optical Telescope data between 2009 February 19 and 2013 June 8. This blazar resides at a redshift of z >= 0.6035, displaying a significantly attenuated gamma-ray flux above 100 GeV due to photon absorption via pair-production with the extragalactic background light. We present more than 100 hr of VERITAS observations over three years, a multiwavelength light curve, and the contemporaneous spectral energy distributions. The source shows a higher flux of (2.1 +/- 0.3) x 10(-7) photons m(-2) s(-1) above 120 GeV in 2009 and 2011 as compared to the flux measured in 2013, corresponding to (1.02 +/- 0.08) x 10-7 photons m(-2) s(-1) above 120 GeV. The measured differential very high energy (VHE; E >= 100 GeV) spectral indices are Gamma = 3.8 +/- 0.3, 4.3 +/- 0.6 and 4.5 +/- 0.2 in 2009, 2011, and 2013, respectively. No significant spectral change across the observation epochs is detected. We find no evidence for variability at gamma-ray opacities of greater than tau = 2, where it is postulated that any variability would be small and occur on timescales longer than a year if hadronic cosmic-ray interactions with extragalactic photon fields provide a secondary VHE photon flux. The data cannot rule out such variability due to low statistics.
KW  - BL Lacertae objects: individual (PKS 1424+240)-cosmic background radiation
KW  - gamma rays: galaxies
Y1  - 2014
U6  - https://doi.org/10.1088/2041-8205/785/1/L16
SN  - 2041-8205
SN  - 2041-8213
VL  - 785
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Archer, A.
A1  - Barnacka, Anna
A1  - Beilicke, M.
A1  - Benbow, W.
A1  - Berger, K.
A1  - Bird, R.
A1  - Biteau, Jonathan
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Byrum, K.
A1  - Cardenzana, J. V.
A1  - Cerruti, M.
A1  - Chen, W.
A1  - Chen, Xiaoming
A1  - Ciupik, L.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Dickinson, H. J.
A1  - Dumm, J.
A1  - Eisch, J. D.
A1  - Falcone, A.
A1  - Federici, Simone
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Griffin, S.
A1  - Griffiths, S. T.
A1  - Grube, J.
A1  - Gyuk, G.
A1  - Hakansson, Nils
A1  - Hanna, D.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kertzman, M.
A1  - Khassen, Y.
A1  - Kieda, D.
A1  - Krawczynski, H.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Maier, G.
A1  - McArthur, S.
A1  - McCann, A.
A1  - Meagher, K.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Perkins, J. S.
A1  - Pohl, Manuela
A1  - Popkow, A.
A1  - Prokoph, H.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Rajotte, J.
A1  - Reyes, L. C.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Sembroski, G. H.
A1  - Shahinyan, K.
A1  - Smith, A. W.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Tucci, J. V.
A1  - Tyler, J.
A1  - Varlotta, A.
A1  - Vincent, S.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Welsing, R.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Zajczyk, A.
A1  - Zitzer, B.
T1  - Very-high energy observations of the galactic center region by veritas IN 2010-2012
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - The Galactic center is an interesting region for high-energy (0.1-100 GeV) and very-high-energy (E > 100 GeV) gamma-ray observations. Potential sources of GeV/TeV gamma-ray emission have been suggested, e.g., the accretion of matter onto the supermassive black hole, cosmic rays from a nearby supernova remnant (e.g., Sgr A East), particle acceleration in a plerion, or the annihilation of dark matter particles. The Galactic center has been detected by EGRET and by Fermi/LAT in the MeV/GeV energy band. At TeV energies, the Galactic center was detected with moderate significance by the CANGAROO and Whipple 10 m telescopes and with high significance by H.E.S.S., MAGIC, and VERITAS. We present the results from three years of VERITAS observations conducted at large zenith angles resulting in a detection of the Galactic center on the level of 18 standard deviations at energies above similar to 2.5 TeV. The energy spectrum is derived and is found to be compatible with hadronic, leptonic, and hybrid emission models discussed in the literature. Future, more detailed measurements of the high-energy cutoff and better constraints on the high-energy flux variability will help to refine and/or disentangle the individual models.
KW  - astroparticle physics
KW  - black hole physics
KW  - Galaxy: center
KW  - gamma rays: galaxies
KW  - methods: data analysis
KW  - radiation mechanisms: non-thermal
Y1  - 2014
U6  - https://doi.org/10.1088/0004-637X/790/2/149
SN  - 0004-637X
SN  - 1538-4357
VL  - 790
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Arlt, Olga
A1  - Schwiebs, Anja
A1  - Japtok, Lukasz
A1  - Rueger, Katja
A1  - Katzy, Elisabeth
A1  - Kleuser, Burkhard
A1  - Radeke, Heinfried H.
T1  - Sphingosine-1-Phosphate modulates dendritic cell function: focus on non-migratory effects in vitro and in vivo
JF  - Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry and pharmacology
N2  - Dendritic cells (DCs) are the cutting edge in innate and adaptive immunity. The major functions of these antigen presenting cells are the capture, endosomal processing and presentation of antigens, providing them an exclusive ability to provoke adaptive immune responses and to induce and control tolerance. Immature DCs capture and process antigens, migrate towards secondary lymphoid organs where they present antigens to naive T cells in a well synchronized sequence of procedures referred to as maturation. Indeed, recent research indicated that sphingolipids are modulators of essential steps in DC homeostasis. It has been recognized that sphingolipids not only modulate the development of DC subtypes from precursor cells but also influence functional activities of DCs such as antigen capture, and cytokine profiling. Thus, it is not astonishing that sphingolipids and sphingolipid metabolism play a substantial role in inflammatory diseases that are modulated by DCs. Here we highlight the function of sphingosine 1-phosphate (S1P) on DC homeostasis and the role of SIP and SW metabolism in inflammatory diseases.
KW  - Sphingosine-1-phosphate
KW  - Dendritic cells
KW  - Fingolimod
KW  - IL-12
KW  - Inflammation
Y1  - 2014
U6  - https://doi.org/10.1159/000362982
SN  - 1015-8987
SN  - 1421-9778
VL  - 34
IS  - 1
SP  - 27
EP  - 44
PB  - Karger
CY  - Basel
ER  - 
TY  - CHAP
A1  - Arlt, Olga
A1  - Schwiebs, Anja
A1  - Pfarr, Kathrin
A1  - Ranglack, Annika
A1  - Bouzas, Ferreiros Nerea
A1  - Schreiber, Yannick
A1  - Neuber, Corinna
A1  - Kleuser, Burkhard
A1  - Pfeilschifter, Josef M.
A1  - Radeke, Heinfried H.
T1  - Dynamic interaction between sphingolipid enzymes, S1P and inflammatory cytokine regulation in dendritic cells
T2  - NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Y1  - 2014
SN  - 0028-1298
SN  - 1432-1912
VL  - 387
SP  - S91
EP  - S91
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Arni, Patrick
A1  - Caliendo, Marco
A1  - Künn, Steffen
A1  - Zimmermann, Klaus F.
T1  - The IZA evaluation dataset survey
BT  - a scientific use file
T2  - Postprints der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe
N2  - This reference paper describes the sampling and contents of the IZA Evaluation Dataset Survey and outlines its vast potential for research in labor economics. The data have been part of a unique IZA project to connect administrative data from the German Federal Employment Agency with innovative survey data to study the out-mobility of individuals to work. This study makes the survey available to the research community as a Scientific Use File by explaining the development, structure, and access to the data. Furthermore, it also summarizes previous findings with the survey data.
T3  - Zweitveröffentlichungen der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe - 122 
KW  - survey data
KW  - scientific use file
KW  - labor market policies
KW  - evaluation
KW  - migration
KW  - ethnicity
KW  - attitudes
KW  - behavior
KW  - skills
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-435204
SN  - 1867-5808
IS  - 122
ER  - 
TY  - THES
A1  - Arnold, Anne
T1  - Modeling photosynthesis and related metabolic processes : from detailed examination to consideration of the metabolic context
T1  - Modellierung von Photosynthese und damit zusammenhängende metabolische Prozesse : von detaillierter Betrachtung hin zur Erörterung im metabolischen Kontext
N2  - Mathematical modeling of biological systems is a powerful tool to systematically investigate the functions of biological processes and their relationship with the environment. To obtain accurate and biologically interpretable predictions, a modeling framework has to be devised whose assumptions best approximate the examined scenario and which copes with the trade-off of complexity of the underlying mathematical description: with attention to detail or high coverage. Correspondingly, the system can be examined in detail on a smaller scale or in a simplified manner on a larger scale. In this thesis, the role of photosynthesis and its related biochemical processes in the context of plant metabolism was dissected by employing modeling approaches ranging from kinetic to stoichiometric models. The Calvin-Benson cycle, as primary pathway of carbon fixation in C3 plants, is the initial step for producing starch and sucrose, necessary for plant growth. Based on an integrative analysis for model ranking applied on the largest compendium of (kinetic) models for the Calvin-Benson cycle, those suitable for development of metabolic engineering strategies were identified. Driven by the question why starch rather than sucrose is the predominant transitory carbon storage in higher plants, the metabolic costs for their synthesis were examined. The incorporation of the maintenance costs for the involved enzymes provided a model-based support for the preference of starch as transitory carbon storage, by only exploiting the stoichiometry of synthesis pathways. Many photosynthetic organisms have to cope with processes which compete with carbon fixation, such as photorespiration whose impact on plant metabolism is still controversial. A systematic model-oriented review provided a detailed assessment for the role of this pathway in inhibiting the rate of carbon fixation, bridging carbon and nitrogen metabolism, shaping the C1 metabolism, and influencing redox signal transduction. The demand of understanding photosynthesis in its metabolic context calls for the examination of the related processes of the primary carbon metabolism. To this end, the Arabidopsis core model was assembled via a bottom-up approach. This large-scale model can be used to simulate photoautotrophic biomass production, as an indicator for plant growth, under so-called optimal, carbon-limiting and nitrogen-limiting growth conditions. Finally, the introduced model was employed to investigate the effects of the environment, in particular, nitrogen, carbon and energy sources, on the metabolic behavior. This resulted in a purely stoichiometry-based explanation for the experimental evidence for preferred simultaneous acquisition of nitrogen in both forms, as nitrate and ammonium, for optimal growth in various plant species. The findings presented in this thesis provide new insights into plant system's behavior, further support existing opinions for which mounting experimental evidences arise, and posit novel hypotheses for further directed large-scale experiments.
N2  - Mathematische Modellierung biologischer Systeme eröffnet die Möglichkeit systematisch die Funktionsweise biologischer Prozesse und ihrer Wechselwirkungen mit der Umgebung zu untersuchen. Um präzise und biologisch relevante Vorhersagen treffen zu können, muss eine Modellierungsstrategie konzipiert werden, deren Annahmen das untersuchte Szenario bestmöglichst widerspiegelt und die dem Trade-off der Komplexität der zugrunde liegenden mathematischen Beschreibung gerecht wird: Detailtreue gegenüber Größe. Dementsprechend kann das System detailliert, in kleinerem Umfang oder in vereinfachter Darstellung im größeren Maßstab untersucht werden. In dieser Arbeit wird mittels verschiedener Modellierungsansätze, wie kinetischen und stöchiometrischen Modellen, die Rolle der Photosynthese und damit zusammenhängender biochemischer Prozesse im Rahmen des Pflanzenstoffwechsels analysiert. Der Calvin-Benson-Zyklus, als primärer Stoffwechselweg der Kohlenstofffixierung in C3-Pflanzen, ist der erste Schritt der Stärke- und Saccharoseproduktion, welche maßgeblich für das Wachstum von Pflanzen sind. Basierend auf einer integrativen Analyse zur Modellklassifizierung wurden aus der größten bekannten Sammlung von (kinetischen) Modellen des Calvin-Benson-Zyklus diejenigen ermittelt, die für die Entwicklung von Metabolic-Engineering-Strategien geeignet sind. Angeregt von der Fragestellung warum Kohlenstoff transitorisch vorwiegend in Form von Stärke anstatt Saccharose gespeichert wird, wurden die metabolischen Kosten beider Syntheseprozesse genauer betrachtet. Die Einbeziehung der Bereitstellungskosten der beteiligten Enzyme stützt die Tatsache, dass bevorzugt Stärke als temporärer Kohlenstoffspeicher dient. Die entprechende Untersuchung erfolgte einzig auf Grundlage der Stöchiometrie der Synthesewege. In vielen photosynthetisch-aktiven Organismen findet zudem Photorespiration statt, die der Kohlenstofffixierung entgegenwirkt. Die genaue Bedeutung der Photorespiration für den Pflanzenmetabolismus ist noch umstritten. Eine detaillierte Einschätzung der Rolle dieses Stoffwechselweges bezüglich der Inhibierung der Kohlenstofffixierungsrate, der Verknüpfung von Kohlenstoff- und Stickstoffmetabolismus, der Ausprägung des C1-Stoffwechsels sowie die Einflussnahme auf die Signaltransduktion wurde in einer modell-basierten, kritischen Analyse vorgenommen. Um die Photosynthese in ihrem metabolischen Kontext verstehen zu können, ist die Betrachtung der angrenzenden Prozesse des primären Kohlenstoffmetabolismus unverzichtbar. Hierzu wurde in einem Bottom-up Ansatz das Arabidopsis core Modell entworfen, mittels dessen die Biomasseproduktion, als Indikator für Pflanzenwachtum, unter photoautotrophen Bedingungen simuliert werden kann. Neben sogenannten optimalen Wachstumsbedingungen kann dieses großangelegte Modell auch kohlenstoff- und stickstofflimitierende Umweltbedingungen simulieren. Abschließend wurde das vorgestellte Modell zur Untersuchung von Umwelteinflüssen auf das Stoffwechselverhalten herangezogen, im speziellen verschiedene Stickstoff-, Kohlenstoff- und Energiequellen. Diese auschließlich auf der Stöchiometrie basierende Analyse bietet eine Erklärung für die bevorzugte, gleichzeitige Aufnahme von Nitrat und Ammonium, wie sie in verschiedenen Spezies für optimales Wachstum experimentell beobachtet wurde. Die Resultate dieser Arbeit liefern neue Einsichten in das Verhalten von pflanzlichen Systemen, stützen existierende Ansichten, für die zunehmend experimentelle Hinweise vorhanden sind, und postulieren neue Hypothesen für weiterführende großangelegte Experimente.
KW  - stöchiometrische Modellierung
KW  - kinetische Modellierung
KW  - metabolische Netzwerke
KW  - metabolische Kosten
KW  - Photosynthese
KW  - stoichiometric modeling
KW  - kinetic modeling
KW  - metabolic networks
KW  - metabolic costs
KW  - photosynthesis
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-72277
ER  - 
TY  - JOUR
A1  - Arnold, Anne
A1  - Nikoloski, Zoran
T1  - In search for an accurate model of the photosynthetic carbon metabolism
JF  - Mathematics and computers in simulation : transactions of IMACS
N2  - The photosynthetic carbon metabolism, including the Calvin-Benson cycle, is the primary pathway in C-3-plants, producing starch and sucrose from CO2. Understanding the interplay between regulation and efficiency of this pathway requires the development of mathematical models which would explain the observed dynamics of metabolic transformations. Here, we address this question by casting the existing models of Calvin-Benson cycle and the end-product processes into an analysis framework which not only facilitates the comparison of the different models, but also allows for their ranking with respect to chosen criteria, including stability, sensitivity, robustness and/or compliance with experimental data. The importance of the photosynthetic carbon metabolism for the increase of plant biomass has resulted in many models with various levels of detail. We provide the largest compendium of 15 existing, well-investigated models together with a comprehensive classification as well as a ranking framework to determine the best-performing models for metabolic engineering and planning of in silica experiments. The classification can be additionally used, based on the model structure, as a tool to identify the models which match best the experimental design. The provided ranking is just one alternative to score models and, by changing the weighting factor, this framework also could be applied for selection of other criteria of interest.
KW  - Calvin-Benson cycle
KW  - Carbon metabolism
KW  - Model ranking
KW  - Differential and algebraic equations
Y1  - 2014
U6  - https://doi.org/10.1016/j.matcom.2012.03.011
SN  - 0378-4754
SN  - 1872-7166
VL  - 96
SP  - 171
EP  - 194
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Arridge, Christopher S.
A1  - Achilleos, N.
A1  - Agarwal, Jessica
A1  - Agnor, C. B.
A1  - Ambrosi, R.
A1  - Andre, N.
A1  - Badman, S. V.
A1  - Baines, K.
A1  - Banfield, D.
A1  - Barthelemy, M.
A1  - Bisi, M. M.
A1  - Blum, J.
A1  - Bocanegra-Bahamon, T.
A1  - Bonfond, B.
A1  - Bracken, C.
A1  - Brandt, P.
A1  - Briand, C.
A1  - Briois, C.
A1  - Brooks, S.
A1  - Castillo-Rogez, J.
A1  - Cavalie, T.
A1  - Christophe, B.
A1  - Coates, Andrew J.
A1  - Collinson, G.
A1  - Cooper, John F.
A1  - Costa-Sitja, M.
A1  - Courtin, R.
A1  - Daglis, I. A.
A1  - De Pater, Imke
A1  - Desai, M.
A1  - Dirkx, D.
A1  - Dougherty, M. K.
A1  - Ebert, R. W.
A1  - Filacchione, Gianrico
A1  - Fletcher, Leigh N.
A1  - Fortney, J.
A1  - Gerth, I.
A1  - Grassi, D.
A1  - Grodent, D.
A1  - Grün, Eberhard
A1  - Gustin, J.
A1  - Hedman, M.
A1  - Helled, R.
A1  - Henri, P.
A1  - Hess, Sebastien
A1  - Hillier, J. K.
A1  - Hofstadter, M. H.
A1  - Holme, R.
A1  - Horanyi, M.
A1  - Hospodarsky, George B.
A1  - Hsu, S.
A1  - Irwin, P.
A1  - Jackman, C. M.
A1  - Karatekin, O.
A1  - Kempf, Sascha
A1  - Khalisi, E.
A1  - Konstantinidis, K.
A1  - Kruger, H.
A1  - Kurth, William S.
A1  - Labrianidis, C.
A1  - Lainey, V.
A1  - Lamy, L. L.
A1  - Laneuville, Matthieu
A1  - Lucchesi, D.
A1  - Luntzer, A.
A1  - MacArthur, J.
A1  - Maier, A.
A1  - Masters, A.
A1  - McKenna-Lawlor, S.
A1  - Melin, H.
A1  - Milillo, A.
A1  - Moragas-Klostermeyer, Georg
A1  - Morschhauser, Achim
A1  - Moses, J. I.
A1  - Mousis, O.
A1  - Nettelmann, N.
A1  - Neubauer, F. M.
A1  - Nordheim, T.
A1  - Noyelles, B.
A1  - Orton, G. S.
A1  - Owens, Mathew
A1  - Peron, R.
A1  - Plainaki, C.
A1  - Postberg, F.
A1  - Rambaux, N.
A1  - Retherford, K.
A1  - Reynaud, Serge
A1  - Roussos, Elias
A1  - Russell, C. T.
A1  - Rymer, Am.
A1  - Sallantin, R.
A1  - Sanchez-Lavega, A.
A1  - Santolik, O.
A1  - Saur, J.
A1  - Sayanagi, Km.
A1  - Schenk, P.
A1  - Schubert, J.
A1  - Sergis, N.
A1  - Sittler, E. C.
A1  - Smith, A.
A1  - Spahn, Frank
A1  - Srama, Ralf
A1  - Stallard, T.
A1  - Sterken, V.
A1  - Sternovsky, Zoltan
A1  - Tiscareno, M.
A1  - Tobie, G.
A1  - Tosi, F.
A1  - Trieloff, M.
A1  - Turrini, D.
A1  - Turtle, E. P.
A1  - Vinatier, S.
A1  - Wilson, R.
A1  - Zarkat, P.
T1  - The science case for an orbital mission to Uranus: Exploring the origins and evolution of ice giant planets
JF  - Planetary and space science
N2  - Giant planets helped to shape the conditions we see in the Solar System today and they account for more than 99% of the mass of the Sun's planetary system. They can be subdivided into the Ice Giants (Uranus and Neptune) and the Gas Giants (Jupiter and Saturn), which differ from each other in a number of fundamental ways. Uranus, in particular is the most challenging to our understanding of planetary formation and evolution, with its large obliquity, low self-luminosity, highly asymmetrical internal field, and puzzling internal structure. Uranus also has a rich planetary system consisting of a system of inner natural satellites and complex ring system, five major natural icy satellites, a system of irregular moons with varied dynamical histories, and a highly asymmetrical magnetosphere. Voyager 2 is the only spacecraft to have explored Uranus, with a flyby in 1986, and no mission is currently planned to this enigmatic system. However, a mission to the uranian system would open a new window on the origin and evolution of the Solar System and would provide crucial information on a wide variety of physicochemical processes in our Solar System. These have clear implications for understanding exoplanetary systems. In this paper we describe the science case for an orbital mission to Uranus with an atmospheric entry probe to sample the composition and atmospheric physics in Uranus' atmosphere. The characteristics of such an orbiter and a strawman scientific payload are described and we discuss the technical challenges for such a mission. This paper is based on a white paper submitted to the European Space Agency's call for science themes for its large-class mission programme in 2013.
KW  - Uranus
KW  - Magnetosphere
KW  - Atmosphere
KW  - Natural satellites
KW  - Rings
KW  - Planetary interior
Y1  - 2014
U6  - https://doi.org/10.1016/j.pss.2014.08.009
SN  - 0032-0633
VL  - 104
SP  - 122
EP  - 140
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Arslan, Seçkin
A1  - Aksu-Koc, Ayhan
A1  - Mavis, Ilknur
A1  - Bastiaanse, Roelien
T1  - Finite verb inflections for evidential categories and source
JF  - Journal of pragmatics : an interdisciplinary journal of language studies
KW  - Agrammatic aphasia
KW  - Evidentiality
KW  - Source identification
KW  - Discourse-linking
KW  - Time reference
KW  - Tense and aspect
Y1  - 2014
U6  - https://doi.org/10.1016/j.pragma.2014.07.002
SN  - 0378-2166
SN  - 1879-1387
VL  - 70
SP  - 165
EP  - 181
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Atilaw, Yoseph
A1  - Heydenreich, Matthias
A1  - Ndakala, Albert
A1  - Akala, Hoseah M.
A1  - Kamau, Edwin
A1  - Yenesew, Abiy
T1  - 3-Oxo-14 alpha, 15 alpha-epoxyschizozygine: A new schizozygane indoline alkaloid from Schizozygia coffaeoides
JF  - Phytochemistry letters
N2  - The stem bark extract of Schizozygia coffaeoides (Apocynaceae) showed moderate antiplasmodial activity (IC50 = 8-12 mu g/mL) against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the extract led to the isolation of a new schizozygane indoline alkaloid, named 3-oxo-14 alpha, 15 alpha-epoxyschizozygine. In addition, two dimeric anthraquinones, cassiamin A and cassiamin B, were identified for the first time in the family Apocynaceae. The structures of the isolated compounds were deduced on the basis of spectroscopic evidence. The schizozygane indole alkaloids showed good to moderate antiplasmodial activities (IC50 = 13-52 mu m). (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
KW  - Schizozygia coffaeoides
KW  - Schizozygane indoline alkaloid
KW  - 3-Oxo-14 alpha, 15 alpha-epoxyschizozygine
KW  - Dimeric anthraquinone
KW  - Cassiamin A
KW  - Cassiamin B
Y1  - 2014
U6  - https://doi.org/10.1016/j.phytol.2014.07.003
SN  - 1874-3900
SN  - 1876-7486
VL  - 10
SP  - 28
EP  - 31
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Attermeyer, Katrin
A1  - Hornick, T.
A1  - Kayler, Zachary
A1  - Bahr, A.
A1  - Zwirnmann, E.
A1  - Grossart, Hans-Peter
A1  - Premke, K.
T1  - Enhanced bacterial decomposition with increasing addition of autochthonous to allochthonous carbon without any effect on bacterial community composition
JF  - Biogeosciences
N2  - Dissolved organic carbon (DOC) concentrations - mainly of terrestrial origin - are increasing worldwide in inland waters. Heterotrophic bacteria are the main consumers of DOC and thus determine DOC temporal dynamics and availability for higher trophic levels. Our aim was to study bacterial carbon (C) turnover with respect to DOC quantity and chemical quality using both allochthonous and autochthonous DOC sources. We incubated a natural bacterial community with allochthonous C (C-13-labeled beech leachate) and increased concentrations and pulses (intermittent occurrence of organic matter input) of autochthonous C (phytoplankton lysate). We then determined bacterial C consumption, activities, and community composition together with the C flow through bacteria using stable C isotopes. The chemical analysis of single sources revealed differences in aromaticity and low-and high-molecular-weight substance fractions (LMWS and HMWS, respectively) between allochthonous and autochthonous C sources. Both DOC sources (allochthonous and autochthonous DOC) were metabolized at a high bacterial growth efficiency (BGE) around 50%. In treatments with mixed sources, rising concentrations of added autochthonous DOC resulted in a further, significant increase in bacterial DOC consumption of up to 68% when nutrients were not limiting. This rise was accompanied by a decrease in the humic substance (HS) fraction and an increase in bacterial biomass. Changes in DOC concentration and consumption in mixed treatments did not affect bacterial community composition (BCC), but BCC differed in single vs. mixed incubations. Our study highlights that DOC quantity affects bacterial C consumption but not BCC in nutrient-rich aquatic systems. BCC shifted when a mixture of allochthonous and autochthonous C was provided simultaneously to the bacterial community. Our results indicate that chemical quality rather than source of DOC per se (allochthonous vs. autochthonous) determines bacterial DOC turnover.
Y1  - 2014
U6  - https://doi.org/10.5194/bg-11-1479-2014
SN  - 1726-4170
SN  - 1726-4189
VL  - 11
IS  - 6
SP  - 1479
EP  - 1489
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Audisio, Paolo
A1  - Cline, Andrew R.
A1  - Solano, Emanuela
A1  - Mancini, Emiliano
A1  - Lamanna, Francesco
A1  - Antonini, Gloria
A1  - Trizzino, Marco
T1  - A peculiar new genus and species of pollen-beetle (Coleoptera, Nitidulidae) from eastern Africa, with a molecular phylogeny of related Meligethinae
JF  - Systematics and biodiversity
KW  - new species
KW  - new genus
KW  - molecular analysis
KW  - pollen-beetles
KW  - host-plants
KW  - Asteraceae
KW  - Kenya
KW  - Tarchonanthopria freidbergi
Y1  - 2014
U6  - https://doi.org/10.1080/14772000.2013.877539
SN  - 1477-2000
SN  - 1478-0933
VL  - 12
IS  - 1
SP  - 77
EP  - 91
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Augusiak, Jacqueline
A1  - Van den Brink, Paul J.
A1  - Grimm, Volker
T1  - Merging validation and evaluation of ecological models to 'evaludation': A review of terminology and a practical approach
JF  - Ecological modelling : international journal on ecological modelling and engineering and systems ecolog
N2  - Confusion about model validation is one of the main challenges in using ecological models for decision support, such as the regulation of pesticides. Decision makers need to know whether a model is a sufficiently good representation of its real counterpart and what criteria can be used to answer this question. Unclear terminology is one of the main obstacles to a good understanding of what model validation is, how it works, and what it can deliver. Therefore, we performed a literature review and derived a standard set of terms. 'Validation' was identified as a catch-all term, which is thus useless for any practical purpose. We introduce the term 'evaludation', a fusion of 'evaluation' and 'validation', to describe the entire process of assessing a model's quality and reliability. Considering the iterative nature of model development, the modelling cycle, we identified six essential elements of evaludation: (i) 'data evaluation' for scrutinising the quality of numerical and qualitative data used for model development and testing; (ii) 'conceptual model evaluation' for examining the simplifying assumptions underlying a model's design; (iii) 'implementation verification' for testing the model's implementation in equations and as a computer programme; (iv) 'model output verification' for comparing model output to data and patterns that guided model design and were possibly used for calibration; (v) 'model analysis' for exploring the model's sensitivity to changes in parameters and process formulations to make sure that the mechanistic basis of main behaviours of the model has been well understood; and (vi) 'model output corroboration' for comparing model output to new data and patterns that were not used for model development and parameterisation. Currently, most decision makers require 'validating' a model by testing its predictions with new experiments or data. Despite being desirable, this is neither sufficient nor necessary for a model to be useful for decision support. We believe that the proposed set of terms and its relation to the modelling cycle can help to make quality assessments and reality checks of ecological models more comprehensive and transparent. (C) 2013 Elsevier B.V. All rights reserved.
KW  - Model validation
KW  - Terminology
KW  - Decision support
KW  - Documentation
KW  - Ecological models
KW  - Risk assessment
Y1  - 2014
U6  - https://doi.org/10.1016/j.ecolmodel.2013.11.009
SN  - 0304-3800
SN  - 1872-7026
VL  - 280
SP  - 117
EP  - 128
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Austin, Gina
A1  - Groppe, Karoline
A1  - Elsner, Birgit
T1  - The reciprocal relationship between executive function and theory of mind in middle childhood: a 1-year longitudinal perspective
JF  - Frontiers in psychology
N2  - There is robust evidence showing a link between executive function (EF) and theory of mind (ToM) in 3-to 5-year-olds. However, it is unclear whether this relationship extends to middle childhood. In addition, there has been much discussion about the nature of this relationship. Whereas some authors claim that ToM is needed for EF, others argue that ToM requires EF. To date, however, studies examining the longitudinal relationship between distinct sub components of EF [i.e., attention shifting, working memory (WM) updating, inhibition] and ToM in middle childhood are rare. The present study examined (1) the relationship between three EF subcomponents (attention shifting, WM updating, inhibition) and ToM in middle childhood, and (2) the longitudinal reciprocal relationships between the EF subcomponents and ToM across a 1-year period. EF and ToM measures were assessed experimentally in a sample of 1,657 children (aged 6-11 years) at time point one (t1) and 1 year later at time point two (t2). Results showed that the concurrent relationships between all three EF subcomponents and ToM pertained in middle childhood at t1 and t2, respectively, even when age, gender, and fluid intelligence were partialle dout. Moreover, cross-lagged structural equation modeling (again, controlling for age, gender, and fluid intelligence, as well as for the earlier levels of the target variables), revealed partial support for the view that early ToM predictslater EF, but stronger evidence for the assumption that early EF predictslater ToM. The latter was found for attention shifting and WM updating, but not for inhibition. This reveals the importance of studying the exact interplay of ToM and EF across childhood development, especially with regard to different EF subcomponents. Most likely, understanding others' mental states at different levels of perspective-taking requires specific EF subcomponents, suggesting developmental change in the relations between EF and ToM across childhood.
KW  - executive function
KW  - theory of mind
KW  - longitudinal
KW  - middle childhood
KW  - attention shifting
KW  - inhibition
KW  - working memory updating
Y1  - 2014
U6  - https://doi.org/10.3389/fpsyg.2014.00655
SN  - 1664-1078
VL  - 5
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Azuma, Yusuke
A1  - Kuekenshoener, Tim
A1  - Ma, Guangyong
A1  - Yasunaga, Jun-ichiro
A1  - Imanishi, Miki
A1  - Tanaka, Gen
A1  - Nakase, Ikuhiko
A1  - Maruno, Takahiro
A1  - Kobayashi, Yuji
A1  - Arndt, Katja Maren
A1  - Matsuoka, Masao
A1  - Futaki, Shiroh
T1  - Controlling leucine-zipper partner recognition in cells through modification of a-g interactions
JF  - Chemical communications
N2  - By focusing on the a-g interactions, successful design and selection were accomplished to obtain a leucine-zipper segment that discriminates the appropriate partner over another that provides very similar patterns of electrostatic interactions.
Y1  - 2014
U6  - https://doi.org/10.1039/c4cc00555d
SN  - 1359-7345
SN  - 1364-548X
VL  - 50
IS  - 48
SP  - 6364
EP  - 6367
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Azuma, Yusuke
A1  - Kükenshöner, Tim
A1  - Ma, Guangyong
A1  - Yasunaga, Jun-ichiro
A1  - Imanishi, Miki
A1  - Tanaka, Gen
A1  - Nakase, Ikuhiko
A1  - Maruno, Takahiro
A1  - Kobayashi, Yuji
A1  - Arndt, Katja Maren
A1  - Matsuoka, Masao
A1  - Futaki, Shiroh
T1  - Controlling leucine-zipper partner recognition in cells through modification of a–g interactions
N2  - By focusing on the a–g interactions, successful design and selection were accomplished to obtain a leucine-zipper segment that discriminates the appropriate partner over another that provides very similar patterns of electrostatic interactions.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 276 
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-98758
ER  - 
TY  - JOUR
A1  - Bacskai-Atkari, Julia
T1  - Cyclical change in Hungarian comparatives
JF  - Diachronica
N2  - This paper examines cyclical changes in comparative subclauses, showing how operators are reanalysed as complementisers via the general mechanism of the relative cycle, and how this is related to whether certain lexical elements have to be deleted at the left periphery. I also show that only operators appearing without a lexical XP can be grammaticalised, which follows from the nature of the formal features associated with the various operator elements. Though the main focus is on Hungarian historical data, the framework can be applied to other languages too, such as German and Italian, since the changes stem from general principles of economy.
KW  - Comparative Deletion
KW  - comparative subclause
KW  - complementiser combinations
KW  - economy
KW  - left periphery
KW  - reanalysis
KW  - relative cycle
KW  - reinforcement
Y1  - 2014
U6  - https://doi.org/10.1075/dia.31.4.01bac
SN  - 0176-4225
SN  - 1569-9714
VL  - 31
IS  - 4
SP  - 465
EP  - 505
PB  - Benjamins
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Bacskai-Atkari, Julia
T1  - Structural case and ambiguity in reduced comparative subclauses in English and German
JF  - Acta linguistica Hungarica : an international journal of linguistics
N2  - The paper argues that structural case assignment properties of English and German reduced comparative subclauses arise from syntactic requirements as well as processes holding at the syntax-phonology interface. I show that constructions involving both an adjectival and a verbal predicate require the subject remnant of the adjectival predicate to be marked for the accusative case both in English and German, which cannot be explained by the notion of default accusative case, especially because German has no default accusative case. I argue that a phonologically defective subclause is reanalysed as part of the matrix clausal object, and hence receives accusative morphological case.
KW  - case syncretism
KW  - comparative subclause
KW  - ellipsis
KW  - structural ambiguity
KW  - structural case
Y1  - 2014
U6  - https://doi.org/10.1556/ALing.61.2014.4.1
SN  - 1216-8076
SN  - 1588-2624
VL  - 61
IS  - 4
SP  - 363
EP  - 378
PB  - Akadémiai Kiadó
CY  - Budapest
ER  - 
TY  - THES
A1  - Bacskai-Atkari, Julia
T1  - The syntax of comparative constructions : operators, ellipsis phenomena and functional left peripheries
T1  - Die Syntax von Vergleichskonstruktionen : Operatoren, Ellipsenphänomene und funktionale linke Peripherien
N2  - Adopting a minimalist framework, the dissertation provides an analysis for the syntactic structure of comparatives, with special attention paid to the derivation of the subclause. The proposed account explains how the comparative subclause is connected to the matrix clause, how the subclause is formed in the syntax and what additional processes contribute to its final structure. In addition, it casts light upon these problems in cross-linguistic terms and provides a model that allows for synchronic and diachronic differences. This also enables one to give a more adequate explanation for the phenomena found in English comparatives since the properties of English structures can then be linked to general settings of the language and hence need no longer be considered as idiosyncratic features of the grammar of English. First, the dissertation provides a unified analysis of degree expressions, relating the structure of comparatives to that of other degrees. It is shown that gradable adjectives are located within a degree phrase (DegP), which in turn projects a quantifier phrase (QP) and that these two functional layers are always present, irrespectively of whether there is a phonologically visible element in these layers. Second, the dissertation presents a novel analysis of Comparative Deletion by reducing it to an overtness constraint holding on operators: in this way, it is reduced to morphological differences and cross-linguistic variation is not conditioned by way of postulating an arbitrary parameter. Cross-linguistic differences are ultimately dependent on whether a language has overt operators equipped with the relevant – [+compr] and [+rel] – features. Third, the dissertation provides an adequate explanation for the phenomenon of Attributive Comparative Deletion, as attested in English, by way of relating it to the regular mechanism of Comparative Deletion. I assume that Attributive Comparative Deletion is not a universal phenomenon, and its presence in English can be conditioned by independent, more general rules, while the absence of such restrictions leads to its absence in other languages. Fourth, the dissertation accounts for certain phenomena related to diachronic changes, examining how the changes in the status of comparative operators led to changes in whether Comparative Deletion is attested in a given language: I argue that only operators without a lexical XP can be grammaticalised. The underlying mechanisms underlying are essentially general economy principles and hence the processes are not language-specific or exceptional. Fifth, the dissertation accounts for optional ellipsis processes that play a crucial role in the derivation of typical comparative subclauses. These processes are not directly related to the structure of degree expressions and hence the elimination of the quantified expression from the subclause; nevertheless, they are shown to be in interaction with the mechanisms underlying Comparative Deletion or the absence thereof.
N2  - Unter Verwendung eines minimalistischen Frameworks wird in der Dissertation eine Analyse der syntaktischen Struktur von Vergleichskonstruktionen vorgestellt, mit besonderem Augenmerk auf der Ableitung des eingebetteten Satzes. Die vorgeschlagene Analyse erklärt, wie der komparative Nebensatz mit dem Matrixsatz verbunden ist, wie der Nebensatz in der Syntax gebildet wird und welche zusätzlichen Prozesse zu seiner endgültigen Struktur beitragen. Außerdem beleuchtet sie diese Probleme aus cross-linguistischer Sicht und bietet ein Modell, das synchrone und diachrone Unterschiede berücksichtigt. Dies ermöglicht auch eine adäquatere Erklärung der Phänomene in englischen Vergleichskonstruktionen, da die Eigenschaften der englischen Strukturen mit allgemeinen Eigenschaften der Sprache verknüpft werden und es daher nicht mehr nötig ist, sie als idiosynkratrische Merkmale der Grammatik der englischen Sprache zu behandeln. Die Dissertation bietet zum einen eine einheitliche Analyse von Gradphrasen, wobei die Struktur von Vergleichskonstruktionen mit der von anderen Graden verbunden wird. Es wird gezeigt, dass graduierbare Adjektive sich in einer Gradphrase (degree phrase, DegP) befinden, die wiederum eine Quantorenphrase (QP) projiziert, und dass diese beiden Funktionsschichten immer vorhanden sind, unabhängig davon, ob es ein phonologisch sichtbares Element in diesen Schichten gibt. Zweitens präsentiert die Dissertation eine neue Analyse von Komparativ-Tilgung (Comparative Deletion), die auf eine Overtheits-Bedingung für Operatoren reduziert wird: dadurch wird das Phänomen auf morphologische Unterschiede zurückgeführt, und cross-linguistische Variation wird nicht durch die Postulierung eines arbiträren Parameters begründet. Cross-linguistische Unterschiede sind letztlich davon abhängig, ob eine Sprache overte Operatoren mit den relevanten Merkmalen – [+ compr] und [+ rel] – hat. Drittens bietet die Dissertation eine adäquate Erklärung für das Phänomen der attributiven Komparativ-Tilgung (Attributive Comparative Deletion), wie man sie im Englischen findet, indem sie mit dem regulären Mechanismus der Komparativ-Tilgung in Zusammenhang gebracht wird. Ich gehe davon aus, dass attributive Komparativ-Tilgung kein universelles Phänomen ist, und dass ihr Vorhandensein im Englischen durch unabhängige, allgemeinere Regeln erfasst werden kann, während das Fehlen solcher Regeln zur Abwesenheit des Phänomens in anderen Sprachen führt. Viertens erklärt die Dissertation bestimmte Phänomene in Bezug auf diachronische Veränderungen und untersucht, wie Veränderungen im Status der Komparativoperatoren beeinflussen, ob Komparativ-Tilgung in einer Sprache vorkommt: Ich argumentiere dafür, dass nur Operatoren ohne eine lexikalische XP grammatikalisiert werden können. Die zugrunde liegenden Mechanismen sind im Wesentlichen allgemeine Prinzipien der Ökonomie, und damit sind die Prozesse nicht sprachspezifisch oder Ausnahmen. Fünftens bietet die Dissertation eine Erklärung für optionale Ellipsenprozesse, die bei der Ableitung von typischen komparativen Nebensätzen eine entscheidende Rolle spielen. Diese Prozesse haben nicht direkt mit der Struktur von Gradphrasen und somit mit der Entfernung der quantifizierten Phrase aus dem Nebensatz zu tun; aber es wird gezeigt, dass sie mit den Mechanismen, die Komparativ-Tilgung oder deren Abwesenheit zugrunde liegen, interagieren.
KW  - komparative Nebensätze
KW  - Komparativ-Tilgung
KW  - Gradphrasen
KW  - linke Peripherie
KW  - Overtheits-Bedingung
KW  - comparative subclauses
KW  - Comparative Deletion
KW  - degree phrases
KW  - left periphery
KW  - overtness requirement
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-71255
SN  - 978-3-86956-301-5
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Badalyan, Artavazd
A1  - Dierich, Marlen
A1  - Stiba, Konstanze
A1  - Schwuchow, Viola
A1  - Leimkühler, Silke
A1  - Wollenberger, Ulla
T1  - Electrical wiring of the aldehyde oxidoreductase PaoABC with a polymer containing osmium redox centers
BT  - biosensors for benzaldehyde and GABA
JF  - Biosensors
N2  - Biosensors for the detection of benzaldehyde and g-aminobutyric acid (GABA) are reported using aldehyde oxidoreductase PaoABC from Escherichia coli immobilized in a polymer containing bound low potential osmium redox complexes. The electrically connected enzyme already electrooxidizes benzaldehyde at potentials below −0.15 V (vs. Ag|AgCl, 1 M KCl). The pH-dependence of benzaldehyde oxidation can be strongly influenced by the ionic strength. The effect is similar with the soluble osmium redox complex and therefore indicates a clear electrostatic effect on the bioelectrocatalytic efficiency of PaoABC in the osmium containing redox polymer. At lower ionic strength, the pH-optimum is high and can be switched to low pH-values at high ionic strength. This offers biosensing at high and low pH-values. A “reagentless” biosensor has been formed with enzyme wired onto a screen-printed electrode in a flow cell device. The response time to addition of benzaldehyde is 30 s, and the measuring range is between 10–150 µM and the detection limit of 5 µM (signal to noise ratio 3:1) of benzaldehyde. The relative standard deviation in a series (n = 13) for 200 µM benzaldehyde is 1.9%. For the biosensor, a response to succinic semialdehyde was also identified. Based on this response and the ability to work at high pH a biosensor for GABA is proposed by coimmobilizing GABA-aminotransferase (GABA-T) and PaoABC in the osmium containing redox polymer.
KW  - redox polymer
KW  - aldehyde oxidoreductase
KW  - ionic strength
KW  - benzaldehyde
KW  - GABA
KW  - biosensor
Y1  - 2014
U6  - https://doi.org/10.3390/bios4040403
VL  - 4
IS  - 4
SP  - 403
EP  - 421
PB  - MDPI
CY  - Basel
ER  - 
TY  - GEN
A1  - Badalyan, Artavazd
A1  - Dierich, Marlen
A1  - Stiba, Konstanze
A1  - Schwuchow, Viola
A1  - Leimkühler, Silke
A1  - Wollenberger, Ulla
T1  - Electrical wiring of the aldehyde oxidoreductase PaoABC with a polymer containing osmium redox centers
BT  - biosensors for benzaldehyde and GABA
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Biosensors for the detection of benzaldehyde and g-aminobutyric acid (GABA) are reported using aldehyde oxidoreductase PaoABC from Escherichia coli immobilized in a polymer containing bound low potential osmium redox complexes. The electrically connected enzyme already electrooxidizes benzaldehyde at potentials below −0.15 V (vs. Ag|AgCl, 1 M KCl). The pH-dependence of benzaldehyde oxidation can be strongly influenced by the ionic strength. The effect is similar with the soluble osmium redox complex and therefore indicates a clear electrostatic effect on the bioelectrocatalytic efficiency of PaoABC in the osmium containing redox polymer. At lower ionic strength, the pH-optimum is high and can be switched to low pH-values at high ionic strength. This offers biosensing at high and low pH-values. A “reagentless” biosensor has been formed with enzyme wired onto a screen-printed electrode in a flow cell device. The response time to addition of benzaldehyde is 30 s, and the measuring range is between 10–150 µM and the detection limit of 5 µM (signal to noise ratio 3:1) of benzaldehyde. The relative standard deviation in a series (n = 13) for 200 µM benzaldehyde is 1.9%. For the biosensor, a response to succinic semialdehyde was also identified. Based on this response and the ability to work at high pH a biosensor for GABA is proposed by coimmobilizing GABA-aminotransferase (GABA-T) and PaoABC in the osmium containing redox polymer.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1082 
KW  - redox polymer
KW  - aldehyde oxidoreductase
KW  - ionic strength
KW  - benzaldehyde
KW  - GABA
KW  - biosensor
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-475070
SN  - 1866-8372
IS  - 1082
ER  - 
TY  - JOUR
A1  - Baerenzung, Julien
A1  - Holschneider, Matthias
A1  - Lesur, Vincent
T1  - Bayesian inversion for the filtered flow at the Earth's core-mantle boundary
JF  - Journal of geophysical research : Solid earth
N2  - The inverse problem of determining the flow at the Earth's core-mantle boundary according to an outer core magnetic field and secular variation model has been investigated through a Bayesian formalism. To circumvent the issue arising from the truncated nature of the available fields, we combined two modeling methods. In the first step, we applied a filter on the magnetic field to isolate its large scales by reducing the energy contained in its small scales, we then derived the dynamical equation, referred as filtered frozen flux equation, describing the spatiotemporal evolution of the filtered part of the field. In the second step, we proposed a statistical parametrization of the filtered magnetic field in order to account for both its remaining unresolved scales and its large-scale uncertainties. These two modeling techniques were then included in the Bayesian formulation of the inverse problem. To explore the complex posterior distribution of the velocity field resulting from this development, we numerically implemented an algorithm based on Markov chain Monte Carlo methods. After evaluating our approach on synthetic data and comparing it to previously introduced methods, we applied it to a magnetic field model derived from satellite data for the single epoch 2005.0. We could confirm the existence of specific features already observed in previous studies. In particular, we retrieved the planetary scale eccentric gyre characteristic of flow evaluated under the compressible quasi-geostrophy assumption although this hypothesis was not considered in our study. In addition, through the sampling of the velocity field posterior distribution, we could evaluate the reliability, at any spatial location and at any scale, of the flow we calculated. The flow uncertainties we determined are nevertheless conditioned by the choice of the prior constraints we applied to the velocity field.
Y1  - 2014
U6  - https://doi.org/10.1002/2013JB010358
SN  - 2169-9313
SN  - 2169-9356
VL  - 119
IS  - 4
SP  - 2695
EP  - 2720
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Baeten, Lander
A1  - Warton, David I.
A1  - Van Calster, Hans
A1  - De Frenne, Pieter
A1  - Verstraeten, Gorik
A1  - Bonte, Dries
A1  - Bernhardt-Römermann, Markus
A1  - Cornelis, Johnny
A1  - Decocq, Guillaume
A1  - Eriksson, Ove
A1  - Hedl, Radim
A1  - Heinken, Thilo
A1  - Hermy, Martin
A1  - Hommel, Patrick
A1  - Kirby, Keith J.
A1  - Naaf, Tobias
A1  - Petrik, Petr
A1  - Walther, Gian-Reto
A1  - Wulf, Monica
A1  - Verheyen, Kris
T1  - A model-based approach to studying changes in compositional heterogeneity
JF  - Methods in ecology and evolution : an official journal of the British Ecological Society
Y1  - 2014
SN  - 2041-210X
SN  - 2041-2096
VL  - 5
IS  - 2
SP  - 156
EP  - 164
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Bagderina, Yulia Yu.
A1  - Tarkhanov, Nikolai Nikolaevich
T1  - Differential invariants of a class of Lagrangian systems with two degrees of freedom
JF  - Journal of mathematical analysis and applications
KW  - Equivalence
KW  - Differential invariant
KW  - Euler-Lagrange equations
Y1  - 2014
U6  - https://doi.org/10.1016/j.jmaa.2013.08.015
SN  - 0022-247X
SN  - 1096-0813
VL  - 410
IS  - 2
SP  - 733
EP  - 749
PB  - Elsevier
CY  - San Diego
ER  - 
TY  - JOUR
A1  - Bahro, Berno
T1  - Can sport form a National-Socialist elite? The example of SS Sports
JF  - The international journal of the history of sport
KW  - Germany
KW  - National Socialism
KW  - Schutzstaffel (SS, Protection Squadron)
KW  - sport and race
KW  - elite sports
Y1  - 2014
U6  - https://doi.org/10.1080/09523367.2014.922546
SN  - 0952-3367
SN  - 1743-9035
VL  - 31
IS  - 12
SP  - 1462
EP  - 1477
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Baier, Heiko
A1  - Metzner, Philipp
A1  - Körzdörfer, Thomas
A1  - Kelling, Alexandra
A1  - Holdt, Hans-Jürgen
T1  - Efficient palladium(II) precatalysts bearing 4,5-dicyanoimidazol-2-ylidene for the Mizoroki-Heck reaction
JF  - European journal of inorganic chemistry : a journal of ChemPubSoc Europe
N2  - The new N-heterocyclic carbene (NHC) complex [PdCl2{(CN)(2)IMes}(PPh3)] (2) ({(CN)(2)IMes}: 4,5-dicyano-1,3-dimesitylimidazol-2-ylidene) and the NHC palladacycle [PdCl(dmba){(CN)(2)IMes}] (3) (dmba: N,N-dimethylbenzylamine) have been synthesized by thermolysis of 4,5-dicyano-1,3-dimesityl-2-(pentafluorophenyl) imidazoline (1) in the presence of suitable palladium(II) precursors. The acyclic complex 2 was formed by ligand exchange using the mononuclear precursor [PdCl2(PPh3)(2)] and the palladacycle 3 was formed by cleavage of the dinuclear chloro-bridged precursor [Pd(mu-Cl)(dmba)](2). The new NHC precursor 1-benzyl-4,5-dicyano-2-(pentafluorophenyl)-3-picolylimidazoline (5) was formed by condensation of pentafluorobenzaldehyde with N-benzyl-N'-picolyldiaminomaleonitrile (4). The NHC palladacycle [PdCl2{(CN)(2)IBzPic}] (6) ({(CN)(2)IBzPic}: 1-benzyl-4,5-dicyano-3-picolylimidazol-2-ylidene) was prepared by in situ thermolysis of 5 in the presence of [PdCl2(PhCN)(2)]. The three palladium(II) complexes were characterized by NMR and IR spectroscopy, mass spectrometry and elemental analysis. In addition, the molecular structures of 2 and 3 were determined by X-ray diffraction. The pi-acidity of (CN)(2)IBzPic was compared with (CN)(2)IMes and perviously reported pi-acidic imidazol-2-ylidenes by NBO analysis. The Mizoroki-Heck (MH) reactions of various aryl halides with n-butyl acrylate were performed in the presence of complexes 2, 3 and 6. The new precatalysts showed high activity in the MH reactions giving good-to-excellent product yields with 0.1 mol-% pre-catalyst. The nature of the catalytically active species of 2, 3 and 6 was investigated by poisoning experiments with mercury and transmission electron microscopy. It was found that palladium nanoparticles formed from the precatalysts were involved in the catalytic process.
KW  - Homogeneous catalysis
KW  - Palladium
KW  - Cross coupling
KW  - Carbene ligands
Y1  - 2014
U6  - https://doi.org/10.1002/ejic.201402040
SN  - 1434-1948
SN  - 1099-0682
IS  - 18
SP  - 2952
EP  - 2960
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Baier, Thomas
A1  - Mendling, Jan
A1  - Weske, Mathias
T1  - Bridging abstraction layers in process mining
JF  - Information systems
N2  - While the maturity of process mining algorithms increases and more process mining tools enter the market, process mining projects still face the problem of different levels of abstraction when comparing events with modeled business activities. Current approaches for event log abstraction try to abstract from the events in an automated way that does not capture the required domain knowledge to fit business activities. This can lead to misinterpretation of discovered process models. We developed an approach that aims to abstract an event log to the same abstraction level that is needed by the business. We use domain knowledge extracted from existing process documentation to semi-automatically match events and activities. Our abstraction approach is able to deal with n:m relations between events and activities and also supports concurrency. We evaluated our approach in two case studies with a German IT outsourcing company. (C) 2014 Elsevier Ltd. All rights reserved.
KW  - Process mining
KW  - Abstraction
KW  - Event mapping
Y1  - 2014
U6  - https://doi.org/10.1016/j.is.2014.04.004
SN  - 0306-4379
SN  - 1873-6076
VL  - 46
SP  - 123
EP  - 139
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - INPR
A1  - Balazadeh, Salma
T1  - Stay-green not always stays green
T2  - Molecular plant
Y1  - 2014
U6  - https://doi.org/10.1093/mp/ssu076
SN  - 1674-2052
SN  - 1752-9867
VL  - 7
IS  - 8
SP  - 1264
EP  - 1266
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Balazadeh, Salma
A1  - Schildhauer, Joerg
A1  - Araujo, Wagner L.
A1  - Munne-Bosch, Sergi
A1  - Fernie, Alisdair R.
A1  - Proost, Sebastian
A1  - Humbeck, Klaus
A1  - Müller-Röber, Bernd
T1  - Reversal of senescence by N resupply to N-starved Arabidopsis thaliana: transcriptomic and metabolomic consequences
JF  - Journal of experimental botany
N2  - Leaf senescence is a developmentally controlled process, which is additionally modulated by a number of adverse environmental conditions. Nitrogen shortage is a well-known trigger of precocious senescence in many plant species including crops, generally limiting biomass and seed yield. However, leaf senescence induced by nitrogen starvation may be reversed when nitrogen is resupplied at the onset of senescence. Here, the transcriptomic, hormonal, and global metabolic rearrangements occurring during nitrogen resupply-induced reversal of senescence in Arabidopsis thaliana were analysed. The changes induced by senescence were essentially in keeping with those previously described; however, these could, by and large, be reversed. The data thus indicate that plants undergoing senescence retain the capacity to sense and respond to the availability of nitrogen nutrition. The combined data are discussed in the context of the reversibility of the senescence programme and the evolutionary benefit afforded thereby. Future prospects for understanding and manipulating this process in both Arabidopsis and crop plants are postulated.
KW  - Arabidopsis
KW  - gene expression
KW  - metabolomics
KW  - nitrogen limitation
KW  - senescence
KW  - transcriptome
Y1  - 2014
U6  - https://doi.org/10.1093/jxb/eru119
SN  - 0022-0957
SN  - 1460-2431
VL  - 65
IS  - 14
SP  - 3975
EP  - 3992
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - GEN
A1  - Bald, Ilko
A1  - Keller, Adrian
T1  - Molecular processes studied at a single-molecule level using DNA origami nanostructures and atomic force microscopy
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - DNA origami nanostructures allow for the arrangement of different functionalities such as proteins, specific DNA structures, nanoparticles, and various chemical modifications with unprecedented precision. The arranged functional entities can be visualized by atomic force microscopy (AFM) which enables the study of molecular processes at a single-molecular level. Examples comprise the investigation of chemical reactions, electron-induced bond breaking, enzymatic binding and cleavage events, and conformational transitions in DNA. In this paper, we provide an overview of the advances achieved in the field of single-molecule investigations by applying atomic force microscopy to functionalized DNA origami substrates.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1146 
KW  - DNA origami
KW  - atomic force microscopy
KW  - single-molecule analysis
KW  - DNA radiation damage
KW  - protein binding
KW  - enzyme reactions
KW  - G quadruplexes
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-475843
SN  - 1866-8372
IS  - 9
SP  - 13803
EP  - 13823
ER  - 
TY  - JOUR
A1  - Bald, Ilko
A1  - Keller, Adrian
T1  - Molecular processes studied at a single-molecule level using DNA origami nanostructures and atomic force microscopy
JF  - Molecules
N2  - DNA origami nanostructures allow for the arrangement of different functionalities such as proteins, specific DNA structures, nanoparticles, and various chemical modifications with unprecedented precision. The arranged functional entities can be visualized by atomic force microscopy (AFM) which enables the study of molecular processes at a single-molecular level. Examples comprise the investigation of chemical reactions, electron-induced bond breaking, enzymatic binding and cleavage events, and conformational transitions in DNA. In this paper, we provide an overview of the advances achieved in the field of single-molecule investigations by applying atomic force microscopy to functionalized DNA origami substrates.
KW  - DNA origami
KW  - atomic force microscopy
KW  - single-molecule analysis
KW  - DNA radiation damage
KW  - protein binding
KW  - enzyme reactions
KW  - G quadruplexes
Y1  - 2014
U6  - https://doi.org/10.3390/molecules190913803
SN  - 1420-3049
VL  - 19
IS  - 9
SP  - 13803
EP  - 13823
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Bald, Ilko
A1  - Keller, Adrian
A1  - Kopyra, Janina
T1  - On the role of fluoro-substituted nucleosides in DNA radiosensitization for tumor radiation therapy
JF  - RSC Advances : an international journal to further the chemical sciences
N2  - Gemcitabine (2′,2′-difluorocytidine) is a well-known radiosensitizer routinely applied in concomitant chemoradiotherapy. During irradiation of biological media with high-energy radiation secondary low-energy (<10 eV) electrons are produced that can directly induce chemical bond breakage in DNA by dissociative electron attachment (DEA). Here, we investigate and compare DEA to the three molecules 2′-deoxycytidine, 2′-deoxy-5-fluorocytidine, and gemcitabine. Fluorination at specific molecular sites, i.e., nucleobase or sugar moiety, is found to control electron attachment and subsequent dissociation pathways. The presence of two fluorine atoms at the sugar ring results in more efficient electron attachment to the sugar moiety and subsequent bond cleavage. For the formation of the dehydrogenated nucleobase anion, we obtain an enhancement factor of 2.8 upon fluorination of the sugar, whereas the enhancement factor is 5.5 when the nucleobase is fluorinated. The observed fragmentation reactions suggest enhanced DNA strand breakage induced by secondary electrons when gemcitabine is incorporated into DNA.
KW  - low-energy electrons
KW  - single-strand breaks
KW  - gas-phase
KW  - chemoradiation therapy
KW  - molecular-mechanisms
KW  - resonant formation
KW  - damage
KW  - attachment
KW  - drugs
Y1  - 2014
U6  - https://doi.org/10.1039/C3RA46735J
SN  - 2046-2069
VL  - 4
IS  - 13
SP  - 6825
EP  - 6829
PB  - Royal Society of Chemistry
ER  - 
TY  - GEN
A1  - Bald, Ilko
A1  - Kopyra, Janina
A1  - Keller, Adrian
T1  - On the role of fluoro-substituted nucleosides in DNA radiosensitization for tumor radiation therapy
N2  - Gemcitabine (2′,2′-difluorocytidine) is a well-known radiosensitizer routinely applied in concomitant chemoradiotherapy. During irradiation of biological media with high-energy radiation secondary low-energy (<10 eV) electrons are produced that can directly induce chemical bond breakage in DNA by dissociative electron attachment (DEA). Here, we investigate and compare DEA to the three molecules 2′-deoxycytidine, 2′-deoxy-5-fluorocytidine, and gemcitabine. Fluorination at specific molecular sites, i.e., nucleobase or sugar moiety, is found to control electron attachment and subsequent dissociation pathways. The presence of two fluorine atoms at the sugar ring results in more efficient electron attachment to the sugar moiety and subsequent bond cleavage. For the formation of the dehydrogenated nucleobase anion, we obtain an enhancement factor of 2.8 upon fluorination of the sugar, whereas the enhancement factor is 5.5 when the nucleobase is fluorinated. The observed fragmentation reactions suggest enhanced DNA strand breakage induced by secondary electrons when gemcitabine is incorporated into DNA.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 167 
KW  - low-energy electrons
KW  - single-strand breaks
KW  - gas-phase
KW  - chemoradiation therapy
KW  - molecular-mechanisms
KW  - resonant formation
KW  - damage
KW  - attachment
KW  - drugs
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-73412
SP  - 6825
EP  - 6829
ER  - 
TY  - JOUR
A1  - Ballato, Paolo
A1  - Strecker, Manfred
T1  - Assessing tectonic and climatic causal mechanisms in foreland-basin stratal architecture: insights from the Alborz Mountains, northern Iran
JF  - Earth surface processes and landforms : the journal of the British Geomorphological Research Group
N2  - The southern foreland basin of the Alborz Mountains of northern Iran is characterized by an approximately 7.3-km-thick sequence of Miocene sedimentary rocks, constituting three basin-wde coarsening-upward units spanning a period of 10(6)years. We assess available magnetostratigraphy, paleoclimatic reconstructions, stratal architecture, records of depositional environments, and sediment-provenance data to characterize the relationships between tectonically-generated accommodation space (A) and sediment supply (S). Our analysis allows an inversion of the stratigraphy for particular forcing mechanisms, documenting causal relationships, and providing a basis to decipher the relative contributions of tectonics and climate (inferred changes in precipitation) in controlling sediment supply to the foreland basin. Specifically, A/S>1, typical of each basal unit (17.5-16.0, 13.8-13.1 and 10.3-9.6Ma), is associated with sharp facies retrogradation and reflects substantial tectonic subsidence. Within these time intervals, arid climatic conditions, changes in sediment provenance, and accelerated exhumation in the orogen suggest that sediment supply was most likely driven by high uplift rates. Conversely, A/S<1 (13.8 and 13.8-11Ma, units 1, and 2) reflects facies progradation during a sharp decline in tectonic subsidence caused by localized intra-basinal uplift. During these time intervals, climate continued to be arid and exhumation active, suggesting that sediment supply was again controlled by tectonics. A/S<1, at 11-10.3Ma and 9-6-7.6Ma (and possibly 6.2; top of units 2 and 3), is also associated with two episodes of extensive progradation, but during wetter phases. The first episode appears to have been linked to a pulse in sediment supply driven by an increase in precipitation. The second episode reflects a balance between a climatically-induced increase in sediment supply and a reduction of subsidence through the incorporation of the proximal foreland into the orogenic wedge. This in turn caused an expansion of the catchment and a consequent further increase in sediment supply.
KW  - sediment supply
KW  - climatic and tectonic forcing
KW  - accommodation-space
KW  - sediment-supply ratio (A /S)
KW  - foreland-basin stratigraphy
KW  - Alborz Mountains
Y1  - 2014
U6  - https://doi.org/10.1002/esp.3480
SN  - 0197-9337
SN  - 1096-9837
VL  - 39
IS  - 1
SP  - 110
EP  - 125
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - THES
A1  - Balzer, Arnim
T1  - Crab flare observations with H.E.S.S. phase II
T1  - Crab Flare Observations with H.E.S.S. Phase II
N2  - The H.E.S.S. array is a third generation Imaging Atmospheric Cherenkov Telescope (IACT) array. It is located in the Khomas Highland in Namibia, and measures very high energy (VHE) gamma-rays. In Phase I, the array started data taking in 2004 with its four identical 13 m telescopes. Since then, H.E.S.S. has emerged as the most successful IACT experiment to date. Among the almost 150 sources of VHE gamma-ray radiation found so far, even the oldest detection, the Crab Nebula, keeps surprising the scientific community with unexplained phenomena such as the recently discovered very energetic flares of high energy gamma-ray radiation. During its most recent flare, which was detected by the Fermi satellite in March 2013, the Crab Nebula was simultaneously observed with the H.E.S.S. array for six nights. The results of the observations will be discussed in detail during the course of this work. During the nights of the flare, the new 24 m × 32 m H.E.S.S. II telescope was still being commissioned, but participated in the data taking for one night. To be able to reconstruct and analyze the data of the H.E.S.S. Phase II array, the algorithms and software used by the H.E.S.S. Phase I array had to be adapted. The most prominent advanced shower reconstruction technique developed by de Naurois and Rolland, the template-based model analysis, compares real shower images taken by the Cherenkov telescope cameras with shower templates obtained using a semi-analytical model. To find the best fitting image, and, therefore, the relevant parameters that describe the air shower best, a pixel-wise log-likelihood fit is done. The adaptation of this advanced shower reconstruction technique to the heterogeneous H.E.S.S. Phase II array for stereo events (i.e. air showers seen by at least two telescopes of any kind), its performance using MonteCarlo simulations as well as its application to real data will be described.
N2  - Das H.E.S.S. Experiment misst sehr hochenergetische Gammastrahlung im Khomas Hochland von Namibia. Es ist ein sogenanntes abbildendes atmosphärisches Cherenkov-Teleskopsystem welches in der 1. Phase, die im Jahr 2004 mit der Datennahme begann, aus vier identischen 13 m Spiegelteleskopen bestand. Seitdem hat sich H.E.S.S. als das erfolgreichstes Experiment in der bodengebundenen Gammastrahlungsastronomie etabliert. Selbst die älteste der mittlerweile fast 150 entdeckten Quellen von sehr hochenergetischer Gammastrahlung, der Krebsnebel, fasziniert immernoch Wissenschaftler mit neuen bisher unbekannten und unerwarteten Phänomenen. Ein Beispiel dafür sind die vor kurzem entdeckten sehr energiereichen Ausbrüche von hochenergetischer Gammastrahlung. Bei dem letzten deratigen Ausbruch des Krebsnebels im März 2013 hat das H.E.S.S. Experiment für sechs Nächte simultan mit dem Fermi-Satelliten, welcher den Ausbruch entdeckte, Daten genommen. Die Analyse der Daten, deren Ergebnis und deren Interpretation werden im Detail in dieser Arbeit vorgestellt. Während dieser Beobachtungen befand sich ein neues 24 m × 32 m großes Spiegelteleskop, das H.E.S.S. II- Teleskop, noch in seiner Inbetriebnahme, trotzdem hat es für eine dieser sechs Nächte an der Datennahme des gesamten Teleskopsystems teilgenommen. Um die Daten rekonstruieren und analysieren zu können, mussten die für die 1. Phase des Experiments entwickelten Algorithmen und die Software des H.E.S.S.- Experiments angepasst werden. Die fortschrittlichste Schauerrekonstruktionsmethode, welche von de Naurois und Rolland entwickelt wurde, basiert auf dem Vergleich von echten Schauerbildern, die mit Hilfe der Cherenkov-Kameras der einzelnen Teleskope aufgenommen wurden, mit Schauerschablonen die mit Hilfe eines semianalytischen Modells erzeugt wurden. Das am besten passende Bild und damit auch alle relevanten Schauerparameter, wird mit Hilfe einer pixelweisen Loglikelihood-Anpassung ermittelt. Die nötigen Änderungen um Multiteleskopereignisse, welche vom heterogenen H.E.S.S. Phase II Detektor gemessen wurden, mit Hilfe dieser fortschrittlichen Schauerrekonstruktionsmethode analysieren zu können, sowie die resultierenden Ergebnisse von MonteCarlo-Simulationen, als auch die Anwendung auf echte Daten, werden im Rahmen dieser Arbeit präsentiert.
KW  - Gammastrahlungsastronomie
KW  - Rekonstruktionsmethoden
KW  - Datenanalyse
KW  - Krebsnebel
KW  - gamma-ray astronomy
KW  - reconstruction methods
KW  - data analysis
KW  - Crab Nebula
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-72545
ER  - 
TY  - JOUR
A1  - Balzer, Arnim
A1  - Fuessling, M.
A1  - Gajdus, M.
A1  - Goering, D.
A1  - Lopatin, A.
A1  - de Naurois, M.
A1  - Schlenker, S.
A1  - Schwanke, U.
A1  - Stegmann, Christian
T1  - The HESS central data acquisition system
JF  - Astroparticle physics
KW  - DAQ
KW  - Data acquisition
KW  - VHE
KW  - Gamma ray astronomy
KW  - HESS
Y1  - 2014
U6  - https://doi.org/10.1016/j.astropartphys.2013.11.007
SN  - 0927-6505
SN  - 1873-2852
VL  - 54
SP  - 67
EP  - 80
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - THES
A1  - Bamberg, Marlene
T1  - Planetary mapping tools applied to floor-fractured craters on Mars
T1  - Planetare Analysewerkzeuge am Anwendungsgebiet von Kratern mit zerbrochenen Boeden auf dem Mars
N2  - Planetary research is often user-based and requires considerable skill, time, and effort. Unfortunately, self-defined boundary conditions, definitions, and rules are often not documented or not easy to comprehend due to the complexity of research. This makes a comparison to other studies, or an extension of the already existing research, complicated. Comparisons are often distorted, because results rely on different, not well defined, or even unknown boundary conditions. The purpose of this research is to develop a standardized analysis method for planetary surfaces, which is adaptable to several research topics. The method provides a consistent quality of results. This also includes achieving reliable and comparable results and reducing the time and effort of conducting such studies. A standardized analysis method is provided by automated analysis tools that focus on statistical parameters. Specific key parameters and boundary conditions are defined for the tool application. The analysis relies on a database in which all key parameters are stored. These databases can be easily updated and adapted to various research questions. This increases the flexibility, reproducibility, and comparability of the research. However, the quality of the database and reliability of definitions directly influence the results. To ensure a high quality of results, the rules and definitions need to be well defined and based on previously conducted case studies. The tools then produce parameters, which are obtained by defined geostatistical techniques (measurements, calculations, classifications). The idea of an automated statistical analysis is tested to proof benefits but also potential problems of this method. In this study, I adapt automated tools for floor-fractured craters (FFCs) on Mars. These impact craters show a variety of surface features, occurring in different Martian environments, and having different fracturing origins. They provide a complex morphological and geological field of application. 433 FFCs are classified by the analysis tools due to their fracturing process. Spatial data, environmental context, and crater interior data are analyzed to distinguish between the processes involved in floor fracturing. Related geologic processes, such as glacial and fluvial activity, are too similar to be separately classified by the automated tools. Glacial and fluvial fracturing processes are merged together for the classification. The automated tools provide probability values for each origin model. To guarantee the quality and reliability of the results, classification tools need to achieve an origin probability above 50 %. This analysis method shows that 15 % of the FFCs are fractured by intrusive volcanism, 20 % by tectonic activity, and 43 % by water & ice related processes. In total, 75 % of the FFCs are classified to an origin type. This can be explained by a combination of origin models, superposition or erosion of key parameters, or an unknown fracturing model. Those features have to be manually analyzed in detail. Another possibility would be the improvement of key parameters and rules for the classification. This research shows that it is possible to conduct an automated statistical analysis of morphologic and geologic features based on analysis tools. Analysis tools provide additional information to the user and are therefore considered assistance systems.
N2  - Planetenforschung umfasst oft zeitintensive Projekte, bei denen Expertise und Erfahrung eine wesentliche Rolle spielen. Auf Grund äusserst komplexer und sich selten wiederholender Forschungsfragen sind Annahmen, Definitionen und Regeln zur Lösung dieser Fragen nicht leicht nachvollziehbar oder aber nicht eindeutig dokumentiert. Ein Vergleich der Ergebnisse unterschiedlicher Forscher zum selben Thema oder eine Erweiterung der Forschungsfrage macht dies somit nur schwer möglich. Vergleiche liefern oftmals verzerrte Ergebnisse, da die Ausgangslage und Randbedingungen unterschiedlich definiert worden sind. Das Ziel dieser Arbeit ist es eine Standardmethode zur Oberflächenanalyse zu entwickeln, die auf zahlreiche Untersuchungsfragen angewandt werden kann. Eine gleichbleibende Qualität der Ergebnisse muss durch diese Methode gewährleistet sein. Ein weiteres Ziel ist es, dass diese Methode ohne Vorwissen und Expertise angewandt werden kann und die Ergebnisse in kurzer Zeit vorliegen. Ausserdem müssen die Ergebnisse vergleichbar und nachvollziehbar sein. Automatisch operierende Analysewerkzeuge können die zahlreichen Anforderungen erfüllen und als Standardmethode dienen. Statistische Ergebnisse werden durch diese Methode erzielt. Die Werkzeuge basieren auf vordefinierten, geowissenschaftlichen Techniken und umfassen Messungen, Berechnungen und Klassifikationen der zu untersuchenden Oberflächenstrukturen. Für die Anwendung dieser Werkzeuge müssen Schlüsselstrukturen und Randbedingungen definiert werden. Des Weiteren benötigen die Werkzeuge eine Datenbank, in der alle Oberflächenstrukturen, aber auch Informationen zu den Randbedingungen gespeichert sind. Es ist mit geringem Aufwand möglich, Datenbanken zu aktualisieren und sie auf verschiedenste Fragestellungen zu adaptieren. Diese Tatsache steigert die Flexibilität, Reproduzierbarkeit und auch Vergleichbarkeit der Untersuchung. Die vordefinierten Randbedingungen und die Qualität der Datenbank haben jedoch auch direkten Einfluss auf die Qualität der Ergebnisse. Um eine gleichbleibend hohe Qualität der Untersuchung zu gewährleisten muss sichergestellt werden, dass alle vordefinierten Bedingungen eindeutig sind und auf vorheriger Forschung basieren. Die automatisch operierenden Analysewerkzeuge müssen als mögliche Standardmethode getestet werden. Hierbei geht es darum Vorteile, aber auch Nachteile zu identifizieren und zu bewerten. In dieser Arbeit werden die Analysewerkzeuge auf einen bestimmten Einschlagskratertyp auf dem Mars angewandt. Krater mit zerbrochenen Kraterböden (Floor-Fractured Craters) sind in verschiedensten Regionen auf dem Mars zu finden, sie zeigen zahlreiche Oberflächenstrukturen und wurden durch unterschiedliche Prozesse geformt. All diese Fakten machen diesen Kratertyp zu einem interessanten und im geologischen und morphologischen Sinne sehr komplexen Anwendungsgebiet. 433 Krater sind durch die Werkzeuge analysiert und je nach Entstehungsprozess klassifiziert worden. Für diese Analyse sind Position der Krater, Art des Umfeldes und Strukturen im Kraterinneren ausschlaggebend. Die kombinierten Informationen geben somit Auskunft über die Prozesse, welche zum Zerbrechen des Kraterbodens geführt haben. Die entwickelten Analysewerkzeuge können geologische Prozesse, die sehr ähnlich zueinander sind, von einander abhängig sind und zusätzlich auch dieselben Oberflächenstrukturen formen, nicht eindeutig unterscheiden. Aus diesem Grund sind fluviale und glaziale Entstehungsprozesse für den untersuchten Kratertyp zusammengefasst. Die Analysewerkzeuge liefern Wahrscheinlichkeitswerte für drei mögliche Entstehungsarten. Um die Qualität der Ergebnisse zu verbessern muss eine Wahrscheinlichkeit über 50 % erreicht werden. Die Werkzeuge zeigen, dass 15 % der Krater durch Vulkanismus, 20 % durch Tektonik und 43 % durch Wasser- und Eis-bedingte Prozesse gebildet wurden. Insgesamt kann für 75 % des untersuchten Kratertyps ein potentieller Entstehungsprozess zugeordnet werden. Für 25 % der Krater ist eine Klassifizierung nicht möglich. Dies kann durch eine Kombination von geologischen Prozessen, einer Überprägung von wichtigen Schlüsselstrukturen, oder eines bisher nicht berücksichtigten Prozesses erklärt werden. Zusammenfassend ist zu sagen, dass es möglich ist planetare Oberflächenstrukturen quantitativ durch automatisch operierende Analysewerkzeuge zu erfassen und hinsichtlich einer definierten Fragestellung zu klassifizieren. Zusätzliche Informationen können durch die entwickelten Werkzeuge erhalten werden, daher sind sie als Assistenzsystem zu betrachten.
KW  - Datenbank
KW  - Automatisierung
KW  - Klassifizierung
KW  - geologische Prozesse
KW  - Geomorphologie
KW  - database
KW  - automation
KW  - classification
KW  - geological processes
KW  - geomorphology
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-72104
ER  - 
TY  - JOUR
A1  - Bamberg, Marlene
A1  - Jaumann, Ralf
A1  - Asche, Hartmut
A1  - Kneissl, T.
A1  - Michael, G. G.
T1  - Floor-Fractured Craters on Mars - Observations and Origin
JF  - Planetary and space science
N2  - Floor-Fractured Craters (FFCs) represent an impact crater type, where the infilling is separated by cracks into knobs of different sizes and shapes. This work focuses on the possible processes which form FFCs to understand the relationship between location and geological environment. We generated a global distribution map using new High Resolution Stereo Camera and Context Camera images. Four hundred and twenty-one potential FFCs have been identified on Mars. A strong link exists among floor fracturing, chaotic terrain, outflow channels and the dichotomy boundary. However, FFCs are also found in the Martian highlands. Additionally, two very diverse craters are used as a case study and we compared them regarding appearance of the surface units, chronology and geological processes. Five potential models of floor fracturing are presented and discussed here. The analyses suggest an origin due to volcanic activity, groundwater migration or tensile stresses. Also subsurface ice reservoirs and tectonic activity are taken into account. Furthermore, the origin of fracturing differs according to the location on Mars. (C) 2013 Elsevier Ltd. All rights reserved.
KW  - Distribution
KW  - Volcanic activity
KW  - Fluvial processes
KW  - Infilling
KW  - Polygons
KW  - Tectonic
Y1  - 2014
U6  - https://doi.org/10.1016/j.pss.2013.09.017
SN  - 0032-0633
VL  - 98
SP  - 146
EP  - 162
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Bamyaci, Elif
A1  - Haeussler, Jana
A1  - Kabak, Baris
T1  - The interaction of animacy and number agreement: an experimental investigation
JF  - Lingua : international review of general linguistics
N2  - This paper investigates subject verb agreement in Turkish with particular focus on the role the animacy of plural subjects plays in verbal number marking. Previous descriptive grammars of Turkish (e.g., Sezer, 1978) report an asymmetry in number marking for plural subjects: if the plural subject denotes an animate entity, both plural and singular verbs are possible, whereas only singular verbs are possible when the plural subject denotes an inanimate entity. Using the magnitude estimation method, we measured the well-formedness of simple Turkish sentences consisting of a plural subject and a verb in two groups of participants that differ only in age (mean: 28 years old and 43 years old). The overall results provide an empirical validation of the proposed split between animate and inanimate subjects and suggest that the acceptability of plural agreement is sensitive to even more fine-grained distinctions of animacy. In particular, the plural dispreference was reduced for inanimates with a teleological capacity (in the sense of Folli and Harley, 2008) and for body parts, in comparison to true inanimates (e.g., furniture and clothes). Accordingly, we propose an animacy hierarchy for Turkish that is in line with typological observations (e.g., Corbett, 2000, 2006) and augment it with a further distinction between quasi-animates and inanimates.
 Although less pronounced in sentences with animate subjects, we observed a higher preference for singular verbs over plural verbs across all conditions. This suggests that the singular marking on the verb, which is zero marked in Turkish, is the default. Furthermore, we find a significant effect of age: in the older group, the singular preference is less pronounced across the conditions and almost absent in sentences with an animate subject. Moreover, the older participants made finer distinctions in the animacy hierarchy, further differentiating between two types of quasi-animates (teleologically capable entities vs. entities with inherited animacy). The two generations in our study share the animate inanimate split as well as the sharp contrast between singular and plural agreement in sentences with inanimate subjects; they differ, however, in degree of optionality. Altogether, these results suggest a decrease in the degree of optionality across generations. As in research on language attrition and bilingualism (Hulk and Muller, 2000; Muller and Hulk, 2001; Sorace, 2011), the results accord with the idea that interface phenomena are vulnerable to change; however, non-convergence between generations in our study stemmed from areas that yield gradient rather than categorical results. (C) 2014 Elsevier B.V. All rights reserved.
KW  - Subject verb agreement in Turkish
KW  - Number marking
KW  - Animacy
KW  - Optionality
KW  - Gradience
KW  - Semantics morphosyntax interface
KW  - Language change
Y1  - 2014
U6  - https://doi.org/10.1016/j.lingua.2014.06.005
SN  - 0024-3841
SN  - 1872-6135
VL  - 148
SP  - 254
EP  - 277
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Bandrauk, Andre D.
A1  - Paramonov, Guennaddi K.
T1  - Excitation of muonic molecules dd mu and dt mu by super-intense attosecond soft X-ray laser pulses: Shaped post-laser-pulse muonic oscillations and enhancement of nuclear fusion
JF  - International journal of modern physics : E, Nuclear physics
N2  - The quantum dynamics of muonic molecular ions dd mu and dt mu excited by linearly polarized along the molecular (z)-axis super-intense laser pulses is studied beyond the Born-Oppenheimer approximation by the numerical solution of the time-dependent Schrodinger equation within a three-dimensional model, including the internuclear distance R and muon coordinates z and rho. The peak-intensity of the super-intense laser pulses used in our simulations is I-0 = 3.51 x 10(22) W/cm(2) and the wavelength is lambda(l) = 5nm. In both dd mu and dt mu, expectation values < z > and <rho > of muon demonstrate "post-laser-pulse" oscillations after the ends of the laser pulses. In dd mu post-laser-pulse z-oscillations appear as shaped nonoverlapping "echo-pulses". In dt mu post-laser-pulse muonic z-oscillations appear as comparatively slow large-amplitude oscillations modulated with small-amplitude pulsations. The post-laser-pulse rho-oscillations in both dd mu and dt mu appear, for the most part, as overlapping "echo-pulses". The post-laser-pulse oscillations do not occur if the Born-Oppenheimer approximation is employed. Power spectra generated due to muonic motion along both optically active z and optically passive rho degrees of freedom are calculated. The fusion probability in dt mu can be increased by more than 11 times by making use of three sequential super-intense laser pulses. The energy released from the dt fusion in dt mu can by more than 20 GeV exceed the energy required to produce a usable muon and the energy of the laser pulses used to enhance the fusion. The possibility of power production from the laser-enhanced muon-catalyzed fusion is discussed.
KW  - Muonic molecules
KW  - super-intense laser pulses
KW  - laser-enhanced nuclear fusion
Y1  - 2014
U6  - https://doi.org/10.1142/S0218301314300148
SN  - 0218-3013
SN  - 1793-6608
VL  - 23
IS  - 9
PB  - World Scientific
CY  - Singapore
ER  - 
TY  - JOUR
A1  - Banerjee, Shiladitya
A1  - Saalfrank, Peter
T1  - Vibrationally resolved absorption, emission and resonance Raman spectra of diamondoids: a study based on time-dependent correlation functions
JF  - Physical chemistry, chemical physics : a journal of European Chemical Societies
Y1  - 2014
U6  - https://doi.org/10.1039/c3cp53535e
SN  - 1463-9076
SN  - 1463-9084
VL  - 16
IS  - 1
SP  - 144
EP  - 158
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Banerjee, Shiladitya
A1  - Saalfrank, Peter
T1  - Vibrationally resolved absorption, emission and resonance Raman spectra of diamondoids : a study based on time- dependent correlation functions
Y1  - 2014
UR  - http://pubs.rsc.org/en/content/articlehtml/2014/cp/c3cp53535e
U6  - https://doi.org/10.1039/C3CP53535E
ER  - 
TY  - CHAP
A1  - Baranyai, Dorothea
A1  - Goedtel-Armbrust, Ute
A1  - Nestler, Sebastian
A1  - Kleuser, Burkhard
A1  - Wojnowski, Leszek
T1  - A role for cutaneous CYP3A in vitamin D homeostasis?
T2  - NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Y1  - 2014
SN  - 0028-1298
SN  - 1432-1912
VL  - 387
SP  - S27
EP  - S27
PB  - Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Baroni, Gabriele
A1  - Tarantola, S.
T1  - A general probabilistic framework for uncertainty and global sensitivity analysis of deterministic models: A hydrological case study
JF  - Environmental modelling & software with environment data news
N2  - The present study proposes a General Probabilistic Framework (GPF) for uncertainty and global sensitivity analysis of deterministic models in which, in addition to scalar inputs, non-scalar and correlated inputs can be considered as well. The analysis is conducted with the variance-based approach of Sobol/Saltelli where first and total sensitivity indices are estimated. The results of the framework can be used in a loop for model improvement, parameter estimation or model simplification. The framework is applied to SWAP, a 113 hydrological model for the transport of water, solutes and heat in unsaturated and saturated soils. The sources of uncertainty are grouped in five main classes: model structure (soil discretization), input (weather data), time-varying (crop) parameters, scalar parameters (soil properties) and observations (measured soil moisture). For each source of uncertainty, different realizations are created based on direct monitoring activities. Uncertainty of evapotranspiration, soil moisture in the root zone and bottom fluxes below the root zone are considered in the analysis. The results show that the sources of uncertainty are different for each output considered and it is necessary to consider multiple output variables for a proper assessment of the model. Improvements on the performance of the model can be achieved reducing the uncertainty in the observations, in the soil parameters and in the weather data. Overall, the study shows the capability of the GPF to quantify the relative contribution of the different sources of uncertainty and to identify the priorities required to improve the performance of the model. The proposed framework can be extended to a wide variety of modelling applications, also when direct measurements of model output are not available.
KW  - Global sensitivity analysis
KW  - Non-scalar input factors
KW  - Hydrological model
KW  - Multi-variables
Y1  - 2014
U6  - https://doi.org/10.1016/j.envsoft.2013.09.022
SN  - 1364-8152
SN  - 1873-6726
VL  - 51
SP  - 26
EP  - 34
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Basavaiah, Nathani
A1  - Wiesner, M. G.
A1  - Anoop, Ambili
A1  - Menzel, P.
A1  - Nowaczyk, Norbert R.
A1  - Deenadayalan, K.
A1  - Brauer, Achim
A1  - Gaye, Birgit
A1  - Naumann, R.
A1  - Riedel, N.
A1  - Stebich, M.
A1  - Prasad, Sushma
T1  - Physicochemical analyses of surface sediments from the Lonar Lake, central India - implications for palaeoenvironmental reconstruction
JF  - Fundamental and applied limnology : official journal of the International Association of Theoretical and Applied Limnology
N2  - We report the results of our investigations on the catchment area, surface sediments, and hydrology of the monsoonal Lonar Lake, central India. Our results indicate that the lake is currently stratified with an anoxic bottom layer, and there is a spatial heterogeneity in the sensitivity of sediment parameters to different environmental processes. In the shallow (0-5 m) near shore oxic-suboxic environments the lithogenic and terrestrial organic content is high and spatially variable, and the organics show degradation in the oxic part. Due to aerial exposure resulting from lake level changes of at least 3m, the evaporitic carbonates are not completely preserved. In the deep water (>5 m) anoxic environment the lithogenics are uniformly distributed and the delta C-13 is an indicator not only for aquatic vs. terrestrial plants but also of lake pH and salinity. The isotopic composition of the evaporites is dependent not only on the isotopic composition of source water (monsoon rainfall and stream inflow) and evaporation, but is also influenced by proximity to the isotopically depleted stream inflow. We conclude that in the deep water environment lithogenic content, and isotopic composition of organic matter can be used for palaeoenvironmental reconstruction.
KW  - isotopes
KW  - lonar lake
KW  - modern surface sediments
KW  - magnetic parameters
KW  - monsoon
KW  - palaeoenvironmental proxies
Y1  - 2014
U6  - https://doi.org/10.1127/1863-9135/2014/0515
SN  - 1863-9135
VL  - 184
IS  - 1
SP  - 51
EP  - 68
PB  - Schweizerbart
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Basel, Nicolai
A1  - Harms, Ute
A1  - Prechtl, Helmut
A1  - Weiss, Thomas
A1  - Rothgangel, Martin
T1  - Students' arguments on the science and religion issue: the example of evolutionary theory and Genesis
JF  - Journal of biological education
N2  - Treating creationism as a controversial topic within the science and religion issue in the science classroom has been widely discussed in the recent literature. Some researchers have proposed that this topic is best addressed by focusing on sociocognitive conflict. To prepare new learning opportunities for this approach, it is necessary to know the concrete arguments that students use in their discussions on this issue. Therefore, this study aimed to provide a systematic description of these arguments. For this purpose, upper secondary students (N=43) argued for either the acceptance of evolutionary theory or faith in Genesis in a written speech. The study was conducted during their regular biology and religious education classes. Generated arguments were analysed by qualitative content analysis. Three dimensions of the arguments were described: the content (science or religion), the valuation of the argument (positive or negative), and whether the argument consisted of a descriptive or normative argumentation. The results indicate that students found it easier to generate arguments about the scientific side of the issue; however, these arguments were negatively constructed. The results are discussed with regard to implications for educational approaches for teaching controversial issues at the high-school level.
KW  - evolutionary theory
KW  - argumentation
KW  - science
KW  - religion issue
KW  - controversial issues
Y1  - 2014
U6  - https://doi.org/10.1080/00219266.2013.849286
SN  - 0021-9266
SN  - 2157-6009
VL  - 48
IS  - 4
SP  - 179
EP  - 187
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - THES
A1  - Bathke, Hannes
T1  - An investigation of complex deformation patterns detected by using InSAR at Llaima and Tendürek volcanoes
T1  - Eine Untersuchung von komplexen Erdoberflächenverformungen gemessen mit InSAR, an den Vulkanen Llaima und Tendürek
N2  - Surface displacement at volcanic edifices is related to subsurface processes associated with magma movements, fluid transfers within the volcano edifice and gravity-driven deformation processes. Understanding of associated ground displacements is of importance for assessment of volcanic hazards. For example, volcanic unrest is often preceded by surface uplift, caused by magma intrusion and followed by subsidence, after the withdrawal of magma. Continuous monitoring of the surface displacement at volcanoes therefore might allow the forecasting of upcoming eruptions to some extent. In geophysics, the measured surface displacements allow the parameters of possible deformation sources to be estimated through analytical or numerical modeling. This is one way to improve the understanding of subsurface processes acting at volcanoes. Although the monitoring of volcanoes has significantly improved in the last decades (in terms of technical advancements and number of monitored volcanoes), the forecasting of volcanic eruptions remains puzzling. In this work I contribute towards the understanding of the subsurface processes at volcanoes and thus to the improvement of volcano eruption forecasting. I have investigated the displacement field of Llaima volcano in Chile and of Tendürek volcano in East Turkey by using synthetic aperture radar interferometry (InSAR). Through modeling of the deformation sources with the extracted displacement data, it was possible to gain insights into potential subsurface processes occurring at these two volcanoes that had been barely studied before. The two volcanoes, although of very different origin, composition and geometry, both show a complexity of interacting deformation sources. At Llaima volcano, the InSAR technique was difficult to apply, due to the large decorrelation of the radar signal between the acquisition of images. I developed a model-based unwrapping scheme, which allows the production of reliable displacement maps at the volcano that I used for deformation source modeling. The modeling results show significant differences in pre- and post-eruptive magmatic deformation source parameters. Therefore, I conjecture that two magma chambers exist below Llaima volcano: a post-eruptive deep one and a shallow one possibly due to the pre-eruptive ascent of magma. Similar reservoir depths at Llaima have been confirmed by independent petrologic studies. These reservoirs are interpreted to be temporally coupled. At Tendürek volcano I have found long-term subsidence of the volcanic edifice, which can be described by a large, magmatic, sill-like source that is subject to cooling contraction. The displacement data in conjunction with high-resolution optical images, however, reveal arcuate fractures at the eastern and western flank of the volcano. These are most likely the surface expressions of concentric ring-faults around the volcanic edifice that show low magnitudes of slip over a long time. This might be an alternative mechanism for the development of large caldera structures, which are so far assumed to be generated during large catastrophic collapse events. To investigate the potential subsurface geometry and relation of the two proposed interacting sources at Tendürek, a sill-like magmatic source and ring-faults, I have performed a more sophisticated numerical modeling approach. The optimum source geometries show, that the size of the sill-like source was overestimated in the simple models and that it is difficult to determine the dip angle of the ring-faults with surface displacement data only. However, considering physical and geological criteria a combination of outward-dipping reverse faults in the west and inward-dipping normal faults in the east seem to be the most likely. Consequently, the underground structure at the Tendürek volcano consists of a small, sill-like, contracting, magmatic source below the western summit crater that causes a trapdoor-like faulting along the ring-faults around the volcanic edifice. Therefore, the magmatic source and the ring-faults are also interpreted to be temporally coupled. In addition, a method for data reduction has been improved. The modeling of subsurface deformation sources requires only a relatively small number of well distributed InSAR observations at the earth’s surface. Satellite radar images, however, consist of several millions of these observations. Therefore, the large amount of data needs to be reduced by several orders of magnitude for source modeling, to save computation time and increase model flexibility. I have introduced a model-based subsampling approach in particular for heterogeneously-distributed observations. It allows a fast calculation of the data error variance-covariance matrix, also supports the modeling of time dependent displacement data and is, therefore, an alternative to existing methods.
N2  - Oberflächenverschiebungen an Vulkanen können einerseits durch unterirdische Magmen- oder Fluidbewegungen oder andererseits durch Gravitation verursacht werden. So sind insbesondere vor Eruptionen oft Aufwölbungen an Vulkanen zu beobachten, verursacht durch Magmenintrusion in die Erdkruste. Nach Eruptionen hingegen sinkt das Vulkangebäude aufgrund von Magmenextrusion wieder. Kontinuierliche Messungen an Vulkanen ermöglichen es, Eruptionen teilweise bis auf wenige Tage vorherzusagen. Die gemessenen Oberflächenverschiebungen können in analytischen oder numerischen Modellierungen genutzt werden, um Parameter eines möglichen Quellprozesses abzuschätzen. Auf diese Art und Weise kann das Verständnis über die unterirdischen Prozesse, die an Vulkanen stattfinden, verbessert werden. Obwohl es in den letzten Jahrzehnten eine enorme Entwicklung und Verbesserung der Überwachung von Vulkanen gab, sind viele Vorhersagen sehr vage und ungenau. Mit dieser Arbeit möchte ich einen Beitrag zum Verständnis von unterirdischen Prozessen an Vulkanen und auf lange Sicht gesehen, zur Vorhersage von Eruptionen leisten. Ich habe die Vulkane, Llaima in Chile und Tendürek im Osten der Türkei, mit Hilfe der Interferometrie von Radardaten (InSAR) untersucht. Die somit gemessenen Verschiebungen an der Erdoberfläche ermöglichen es, durch Modellierung der möglichen Deformationsquellen, Informationen über die Untergrundstrukturen dieser beiden bisher kaum erforschten Vulkane zu bekommen. Obwohl unterschiedlich in Aufbau, Gesteinszusammensetzung und Entstehung, zeigen beide Vulkane Anzeichen dafür, dass jeweils mehrere interagierende Deformationsquellen im Untergrund existieren. Am Vulkan Llaima war es schwierig, aufgrund der starken Dekorrelation des Radarsignals zwischen den Satellitenaufnahmen, die InSAR Methode anzuwenden. Ich entwickelte eine Methode um die doppeldeutigen relativen Phasenwerte der Interferogramme modellbasiert in eindeutige relative Phasenwerte umzurechnen. Die damit erzeugten Oberflächenverschiebungskarten am Vulkan eigneten sich nun für eine anschließende Modellierung der Deformationsquelle. Die Modellierungsergebnisse zeigen signifikante Unterschiede zwischen den Parametern der präeruptiven- und posteruptiven Deformationsquellen. Demzufolge könnten zwei unterschiedliche, interagierende Magmenkammern unter Llaima existieren, eine tiefe, posteruptiv aktive Kammer und eine flache, durch den Aufstieg von Magma präeruptiv aktive Kammer. Am Vulkan Tendürek ist eine langfristige, kontinuierliche Senkung des Vulkangebäudes zu beobachten, die mit einem großen, aufgrund von Kühlung sich kontrahierenden, magmatischen Sill, erklärbar ist. Unter Hinzunahme von hochauflösenden, optischen Daten jedoch, sind bei genauerer Untersuchung bogenförmige Strukturen an der Erdoberfläche sichtbar. Diese sind Anzeichen dafür, dass Verwerfungen existieren, die das gesamte Vulkangebäude in einem elliptischen Ring umgeben. Dabei ist zu beobachten, dass die Ringstörungen über Jahrtausende, möglicherweise sogar kontinuierlich, geringe Magnituden von Versatz aufweisen. Bei langer, kontinuierlicher Aktivität über mehrere zehntausende von Jahren, könnte dies ein weiterer Mechanismus zur Entstehung von Calderastrukturen an Vulkanen darstellen, der jedoch sehr langsam verläuft. Im Gegensatz dazu ist die heutige weit verbreitete Auffassung, dass Calderen als Folge katastrophaler Einstürze von Vulkangebäuden entstehen. Um zu untersuchen welche Geometrie die vorgeschlagenen Strukturen Sill und Ringstörungen an Tendürek im Untergund haben könnten, vollführte ich eine weitaus komplexere numerische Modellierung. Diese zeigt, dass die Größe des Sills ohne Berücksichtigung der Ringstörung um ein Vielfaches überschätzt ist. Die Orientierung und Geometrie der Ringstörungen ist jedoch nicht eindeutig nur mit Oberflächenverschiebungsdaten auflösbar. Unter der Berücksichtigung von geologischen und physikalischen Gesichtspunkten sind nach Außen einfallende Aufschiebungen im Westen und nach Innen einfallende Abschiebungen im Osten die plausibelste Erklärung. Außerdem habe ich eine Methode zur Datenreduzierung entwickelt. Abhängig vom zu untersuchenden Prozess sind für die Modellierung von unterirdischen Deformationsquellen verhältnismäßig wenige gut verteilte Messpunkte an der Erdoberfläche ausreichend. Satelliten gestützte Radaraufnahmen haben jedoch oft mehrere Millionen dieser Punkte. Deshalb müssen diese riesigen Datensätze auf eine Art und Weise reduziert werden, dass keine oder nur möglichst wenige Informationen verloren gehen. Für diesen Zweck habe ich, ausgehend von einem existierenden Algorithmus, eine modellbasierte Methode zur Reduzierung von besonders heterogen verteilten Oberflächendaten entwickelt. Diese Methode ist besonders gut auf Zeitreihendatensätze anwendbar und stellt somit eine Alternative zu existierenden Algorithmen dar.
KW  - InSAR
KW  - Deformationsquellenmodellierung
KW  - Llaima Vulkan
KW  - Tendürek Vulkan
KW  - Ringstörungen
KW  - InSAR
KW  - deformation source modeling
KW  - Llaima volcano
KW  - Tendürek volcano
KW  - ring-fault
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-70522
ER  - 
TY  - INPR
A1  - Baudis, Stefan
A1  - Behl, Marc
A1  - Lendlein, Andreas
T1  - Smart polymers for biomedical applications
T2  - Macromolecular chemistry and physics
Y1  - 2014
U6  - https://doi.org/10.1002/macp.201400561
SN  - 1022-1352
SN  - 1521-3935
VL  - 215
IS  - 24
SP  - 2399
EP  - 2402
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Bauer, Barbara
A1  - Vos, Matthijs
A1  - Klauschies, Toni
A1  - Gaedke, Ursula
T1  - Diversity, functional similarity, and top-down control drive synchronization and the reliability of ecosystem function
JF  - The American naturalist : a bi-monthly journal devoted to the advancement and correlation of the biological sciences
N2  - The concept that diversity promotes reliability of ecosystem function depends on the pattern that community-level biomass shows lower temporal variability than species-level biomasses. However, this pattern is not universal, as it relies on compensatory or independent species dynamics. When in contrast within--trophic level synchronization occurs, variability of community biomass will approach population-level variability. Current knowledge fails to integrate how species richness, functional distance between species, and the relative importance of predation and competition combine to drive synchronization at different trophic levels. Here we clarify these mechanisms. Intense competition promotes compensatory dynamics in prey, but predators may at the same time increasingly synchronize, under increasing species richness and functional similarity. In contrast, predators and prey both show perfect synchronization under strong top-down control, which is promoted by a combination of low functional distance and high net growth potential of predators. Under such conditions, community-level biomass variability peaks, with major negative consequences for reliability of ecosystem function.
KW  - biodiversity
KW  - ecosystem services
KW  - population dynamics
KW  - predator-prey system
KW  - species richness
KW  - synchrony
Y1  - 2014
U6  - https://doi.org/10.1086/674906
SN  - 0003-0147
SN  - 1537-5323
VL  - 183
IS  - 3
SP  - 394
EP  - 409
PB  - Univ. of Chicago Press
CY  - Chicago
ER  - 
TY  - JOUR
A1  - Bauer, Maximilian
A1  - Godec, Aljaz
A1  - Metzler, Ralf
T1  - Diffusion of finite-size particles in two-dimensional channels with random wall configurations
JF  - Physical chemistry, chemical physics : a journal of European Chemical Societies
N2  - Diffusion of chemicals or tracer molecules through complex systems containing irregularly shaped channels is important in many applications. Most theoretical studies based on the famed Fick-Jacobs equation focus on the idealised case of infinitely small particles and reflecting boundaries. In this study we use numerical simulations to consider the transport of finite-size particles through asymmetrical two-dimensional channels. Additionally, we examine transient binding of the molecules to the channel walls by applying sticky boundary conditions. We consider an ensemble of particles diffusing in independent channels, which are characterised by common structural parameters. We compare our results for the long-time effective diffusion coefficient with a recent theoretical formula obtained by Dagdug and Pineda
Y1  - 2014
U6  - https://doi.org/10.1039/c3cp55160a
SN  - 1463-9076
SN  - 1463-9084
VL  - 16
IS  - 13
SP  - 6118
EP  - 6128
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Bauer, Maximilian
A1  - Godec, Aljaž
A1  - Metzler, Ralf
T1  - Diffusion of finite-size particles in two-dimensional channels with random wall configurations
JF  - Physical chemistry, chemical physics : PCCP ; a journal of European chemical societies
N2  - Diffusion of chemicals or tracer molecules through complex systems containing irregularly shaped channels is important in many applications. Most theoretical studies based on the famed Fick–Jacobs equation focus on the idealised case of infinitely small particles and reflecting boundaries. In this study we use numerical simulations to consider the transport of finite-size particles through asymmetrical two-dimensional channels. Additionally, we examine transient binding of the molecules to the channel walls by applying sticky boundary conditions. We consider an ensemble of particles diffusing in independent channels, which are characterised by common structural parameters. We compare our results for the long-time effective diffusion coefficient with a recent theoretical formula obtained by Dagdug and Pineda [J. Chem. Phys., 2012, 137, 024107].
KW  - anomalous diffusion
KW  - fractional dynamics
KW  - transport
KW  - nonergodicity
KW  - coefficient
Y1  - 2014
U6  - https://doi.org/10.1039/C3CP55160A
SN  - 1463-9084
SN  - 1463-9076
VL  - 16
IS  - 13
SP  - 6118
EP  - 6128
PB  - RSC Publications
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Bauer, Maximilian
A1  - Godec, Aljaž
A1  - Metzler, Ralf
T1  - Diffusion of finite-size particles in two-dimensional channels with random wall configurations
N2  - Diffusion of chemicals or tracer molecules through complex systems containing irregularly shaped channels is important in many applications. Most theoretical studies based on the famed Fick–Jacobs equation focus on the idealised case of infinitely small particles and reflecting boundaries. In this study we use numerical simulations to consider the transport of finite-size particles through asymmetrical two-dimensional channels. Additionally, we examine transient binding of the molecules to the channel walls by applying sticky boundary conditions. We consider an ensemble of particles diffusing in independent channels, which are characterised by common structural parameters. We compare our results for the long-time effective diffusion coefficient with a recent theoretical formula obtained by Dagdug and Pineda [J. Chem. Phys., 2012, 137, 024107].
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 177 
KW  - anomalous diffusion
KW  - fractional dynamics
KW  - transport
KW  - nonergodicity
KW  - coefficient
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-76199
ER  - 
TY  - JOUR
A1  - Baushev, Anton N.
T1  - Relaxation of dark matter halos: how to match observational data?
JF  - Astronomy and astrophysics : an international weekly journal
N2  - We show that moderate energy relaxation in the formation of dark matter halos invariably leads to profiles that match those observed in the central regions of galaxies. The density profile of the central region is universal and insensitive to either the seed perturbation shape or the details of the relaxation process. The profile has a central core; the multiplication of the central density by the core radius is almost independent of the halo mass, in accordance with observations. In the core area the density distribution behaves as an Einasto profile with low index (n similar to 0.5); it has an extensive region with rho proportional to r(-2) at larger distances. This is exactly the shape that observations suggest for the central region of galaxies. On the other hand, this shape does not fit the galaxy cluster profiles. A possible explanation of this fact is that the relaxation is violent in the case of galaxy clusters; however, it is not violent enough when galaxies or smaller dark matter structures are considered. We discuss the reasons for this.
KW  - dark matter
KW  - Galaxy: structure
KW  - Galaxy: formation
KW  - astroparticle physics
KW  - methods: analytical
Y1  - 2014
U6  - https://doi.org/10.1051/0004-6361/201322730
SN  - 0004-6361
SN  - 1432-0746
VL  - 569
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Baushev, Anton N.
T1  - Galaxy halo formation in the absence of violent relaxation and a universal density profile of the halo center
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - While N-body simulations testify to a cuspy profile of the central region of dark matter halos, observations favor a shallow, cored density profile of the central region of at least some spiral galaxies and dwarf spheroidals. We show that a central profile, very close to the observed one, inevitably forms in the center of dark matter halos if we make a supposition about a moderate energy relaxation of the system during the halo formation. If we assume the energy exchange between dark matter particles during the halo collapse is not too intensive, the profile is universal: it depends almost not at all on the properties of the initial perturbation and is very akin, but not identical, to the Einasto profile with a small Einasto index n similar to 0.5. We estimate the size of the "central core" of the distribution, i.e., the extent of the very central region with a respectively gentle profile, and show that the cusp formation is unlikely, even if the dark matter is cold. The obtained profile is in good agreement with observational data for at least some types of galaxies but clearly disagrees with N-body simulations.
KW  - astroparticle physics
KW  - dark matter
KW  - elementary particles
KW  - large-scale structure of universe
Y1  - 2014
U6  - https://doi.org/10.1088/0004-637X/786/1/65
SN  - 0004-637X
SN  - 1538-4357
VL  - 786
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Becher, Matthias A.
A1  - Grimm, Volker
A1  - Thorbek, Pernille
A1  - Horn, Juliane
A1  - Kennedy, Peter J.
A1  - Osborne, Juliet L.
T1  - BEEHAVE: a systems model of honeybee colony dynamics and foraging to explore multifactorial causes of colony failure
JF  - Journal of applied ecology : an official journal of the British Ecological Society
N2  - BEEHAVE offers a valuable tool for researchers to design and focus field experiments, for regulators to explore the relative importance of stressors to devise management and policy advice and for beekeepers to understand and predict varroa dynamics and effects of management interventions. We expect that scientists and stakeholders will find a variety of applications for BEEHAVE, stimulating further model development and the possible inclusion of other stressors of potential importance to honeybee colony dynamics.
KW  - Apis mellifera
KW  - colony decline
KW  - cross-level interactions
KW  - feedbacks
KW  - foraging
KW  - modelling
KW  - multiple stressors
KW  - multi-agent simulation
KW  - predictive systems ecology
KW  - Varroa destructor
Y1  - 2014
U6  - https://doi.org/10.1111/1365-2664.12222
SN  - 0021-8901
SN  - 1365-2664
VL  - 51
IS  - 2
SP  - 470
EP  - 482
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Bechi, Beatrice
A1  - Herter, Susanne
A1  - McKenna, Shane
A1  - Riley, Christopher
A1  - Leimkühler, Silke
A1  - Turner, Nicholas J.
A1  - Carnell, Andrew J.
T1  - Catalytic bio-chemo and bio-bio tandem oxidation reactions for amide and carboxylic acid synthesis
JF  - Green chemistry : an international journal and green chemistry resource
N2  - A catalytic toolbox for three different water-based one-pot cascades to convert aryl alcohols to amides and acids and cyclic amines to lactams, involving combination of oxidative enzymes (monoamine oxidase, xanthine dehydrogenase, galactose oxidase and laccase) and chemical oxidants (TBHP or Cul(cat)/H2O2) at mild temperatures, is presented. Mutually compatible conditions were found to afford products in good to excellent yields.
Y1  - 2014
U6  - https://doi.org/10.1039/c4gc01321b
SN  - 1463-9262
SN  - 1463-9270
VL  - 16
IS  - 10
SP  - 4524
EP  - 4529
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Bechi, Beatrice
A1  - Herter, Susanne
A1  - McKenna, Shane
A1  - Riley, Christopher
A1  - Leimkühler, Silke
A1  - Turner, Nicholas J.
A1  - Carnell, Andrew J.
T1  - Catalytic bio–chemo and bio–bio tandem oxidation reactions for amide and carboxylic acid synthesis
N2  - A catalytic toolbox for three different water-based one-pot cascades to convert aryl alcohols to amides and acids and cyclic amines to lactams, involving combination of oxidative enzymes (monoamine oxidase, xanthine dehydrogenase, galactose oxidase and laccase) and chemical oxidants (TBHP or CuI(cat)/H2O2) at mild temperatures, is presented. Mutually compatible conditions were found to afford products in good to excellent yields.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 282 
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-99414
ER  - 
TY  - JOUR
A1  - Becker, Christian
T1  - Relative differential cohomology
JF  - Lecture notes in mathematics : a collection of informal reports and seminars
JF  - Lecture Notes in Mathematics
N2  - We study two notions of relative differential cohomology, using the model of differential characters. The two notions arise from the two options to construct relative homology, either by cycles of a quotient complex or of a mapping cone complex. We discuss the relation of the two notions of relative differential cohomology to each other. We discuss long exact sequences for both notions, thereby clarifying their relation to absolute differential cohomology. We construct the external and internal product of relative and absolute characters and show that relative differential cohomology is a right module over the absolute differential cohomology ring. Finally we construct fiber integration and transgression for relative differential characters.
Y1  - 2014
SN  - 978-3-319-07034-6; 978-3-319-07033-9
U6  - https://doi.org/10.1007/978-3-319-07034-6_2
SN  - 0075-8434
VL  - 2112
SP  - 91
EP  - 180
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Becker, Michael
A1  - Neumann, Marko
A1  - Tetzner, Julia
A1  - Böse, Susanne
A1  - Knoppick, Henrike
A1  - Maaz, Kai
A1  - Baumert, Jürgen
A1  - Lehmann, Rainer
T1  - Development? Effects of the transition into academically selective schools
JF  - The journal of educational psychology
N2  - The present study investigates school context effects on psychosocial characteristics (academic self-concept, peer relations, school satisfaction, and school anxiety) of high-achieving and gifted students. Students who did or did not make an early transition from elementary to secondary schools for high-achieving and gifted students in 5th grade in Berlin, Germany, are compared in their psychosocial development. The sample comprises 155 early-entry students who moved to an academically selective secondary school (Gymnasium) and 3,169 regular students who remained in elementary school until the end of 6th grade. Overall, a complex pattern of psychosocial development emerged for all students, with both positive and negative outcomes being observed. Specifically, the transition into academically selective learning environments seemed to come at some cost for psychosocial development. Propensity score matching analysis isolating the effects of selective school intake and the school context effect itself revealed negative contextual effects of early transition to Gymnasium on academic self-concept and school anxiety; additionally, the positive trend in peer relations observed among regular students was not discernible among early-entry students.
KW  - psychosocial development
KW  - transition
KW  - ability grouping
KW  - longitudinal design
KW  - propensity score matching
Y1  - 2014
U6  - https://doi.org/10.1037/a0035425
SN  - 0022-0663
SN  - 1939-2176
VL  - 106
IS  - 2
SP  - 555
EP  - 568
PB  - American Psychological Association
CY  - Washington
ER  - 
TY  - CHAP
A1  - Behl, Marc
A1  - Kratz, Karl
A1  - Nöchel, Ulrich
A1  - Sauter, Tilman
A1  - Lendlein, Andreas
T1  - Polymer networks capable of reversible shape-memory-effects
T2  - Abstracts of papers : joint conference / The Chemical Institute of Cananda, CIC, American Chemical Society, ACS
Y1  - 2014
SN  - 0065-7727
VL  - 248
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Behrens, Maik
A1  - Frank, Oliver
A1  - Rawel, Harshadrai Manilal
A1  - Ahuja, Gaurav
A1  - Potting, Christoph
A1  - Hofmann, Thomas
A1  - Meyerhof, Wolfgang
A1  - Korsching, Sigrun
T1  - ORA1, a Zebrafish Olfactory Receptor Ancestral to All Mammalian V1R Genes, Recognizes 4-Hydroxyphenylacetic Acid, a Putative Reproductive Pheromone
JF  - The journal of biological chemistry
N2  - The teleost v1r-related ora genes are a small, highly conserved olfactory receptor gene family of only six genes, whose direct orthologues can be identified in lineages as far as that of cartilaginous fish. However, no ligands for fish olfactory receptor class A related genes (ORA) had been uncovered so far. Here we have deorphanized the ORA1 receptor using heterologous expression and calcium imaging. We report that zebrafish ORA1 recognizes with high specificity and sensitivity 4-hydroxyphenylacetic acid. The carboxyl group of this compound is required in a particular distance from the aromatic ring, whereas the hydroxyl group in the para-position is not essential, but strongly enhances the binding efficacy. Low concentrations of 4-hydroxyphenylacetic acid elicit increases in oviposition frequency in zebrafish mating pairs. This effect is abolished by naris closure. We hypothesize that 4-hydroxyphenylacetic acid might function as a pheromone for reproductive behavior in zebrafish. ORA1 is ancestral to mammalian V1Rs, and its putative function as pheromone receptor is reminiscent of the role of several mammalian V1Rs as pheromone receptors.
Y1  - 2014
U6  - https://doi.org/10.1074/jbc.M114.573162
SN  - 0021-9258
SN  - 1083-351X
VL  - 289
IS  - 28
SP  - 19778
EP  - 19788
PB  - American Society for Biochemistry and Molecular Biology
CY  - Bethesda
ER  - 
TY  - JOUR
A1  - Beim Graben, Peter
T1  - Contextual emergence of intentionality
JF  - Journal of consciousness studies : controversies in science & the humanities ; an international multi-disciplinary journal
N2  - By means of an intriguing physical example, magnetic surface swimmers, that can be described in terms of Dennett's intentional stance, I reconstruct a hierarchy of necessary and sufficient conditions for the applicability of the intentional strategy. It turns out that the different levels of the intentional hierarchy are contextually emergent from their respective subjacent levels by imposing stability constraints upon them. At the lowest level of the hierarchy, phenomenal physical laws emerge for the coarse-grained description of open, nonlinear, and dissipative non-equilibrium systems in critical states. One level higher, dynamic patterns, such as, for example, magnetic surface swimmers, are contextually emergent as they are invariant under certain symmetry operations. Again one level up, these patterns behave apparently rationally by selecting optimal pathways for the dissipation of energy that is delivered by external gradients. This is in accordance with the restated Second Law of thermodynamics as a stability criterion. At the highest level, true believers are intentional systems that are stable under exchanging their observation conditions.
Y1  - 2014
SN  - 1355-8250
VL  - 21
IS  - 5-6
SP  - 75
EP  - 96
PB  - Imprint Academic
CY  - Exeter
ER  - 
TY  - JOUR
A1  - Beisheim, Marianne
A1  - Liese, Andrea Margit
T1  - Summing up : key findings and avenues for future research
Y1  - 2014
SN  - 978-1-137-35925-0
ER  - 
TY  - JOUR
A1  - Beisheim, Marianne
A1  - Liese, Andrea Margit
A1  - Janetschek, Hannah
A1  - Sarre, Johanna
T1  - Transnational partnerships: conditions for successful service provision in areas of limited statehood
JF  - Governance : an international journal of policy and administration and institutions
Y1  - 2014
U6  - https://doi.org/10.1111/gove.12070
SN  - 0952-1895
SN  - 1468-0491
VL  - 27
IS  - 4
SP  - 655
EP  - 673
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Beisheim, Marianne
A1  - Liese, Andrea Margit
A1  - Lorch, Jasmin
T1  - Introduction : transnationale partnerships for sustainable development
Y1  - 2014
SN  - 978-1-137-35925-0
ER  - 
TY  - JOUR
A1  - Beisheim, Marianne
A1  - Liese, Andrea Margit
A1  - Vosseler, Christian
T1  - Who governs partnershis? on the role board, donors, partners and other stakeholders
Y1  - 2014
SN  - 978-1-137-35925-0
ER  - 
TY  - THES
A1  - Benz, Verena
T1  - Sex-specific differences in the regulation of body weight dynamics and adipose tissue metabolism
Y1  - 2014
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Beshnova, Daria A.
A1  - Cherstvy, Andrey G.
A1  - Vainshtein, Yevhen
A1  - Teif, Vladimir B.
T1  - Regulation of the nucleosome repeat length in vivo by the DNA sequence, protein concentrations and long-range interactions
JF  - PLoS Computational Biology : a new community journal
N2  - The nucleosome repeat length (NRL) is an integral chromatin property important for its biological functions. Recent experiments revealed several conflicting trends of the NRL dependence on the concentrations of histones and other architectural chromatin proteins, both in vitro and in vivo, but a systematic theoretical description of NRL as a function of DNA sequence and epigenetic determinants is currently lacking. To address this problem, we have performed an integrative biophysical and bioinformatics analysis in species ranging from yeast to frog to mouse where NRL was studied as a function of various parameters. We show that in simple eukaryotes such as yeast, a lower limit for the NRL value exists, determined by internucleosome interactions and remodeler action. For higher eukaryotes, also the upper limit exists since NRL is an increasing but saturating function of the linker histone concentration. Counterintuitively, smaller H1 variants or non-histone architectural proteins can initiate larger effects on the NRL due to entropic reasons. Furthermore, we demonstrate that different regimes of the NRL dependence on histone concentrations exist depending on whether DNA sequence-specific effects dominate over boundary effects or vice versa. We consider several classes of genomic regions with apparently different regimes of the NRL variation. As one extreme, our analysis reveals that the period of oscillations of the nucleosome density around bound RNA polymerase coincides with the period of oscillations of positioning sites of the corresponding DNA sequence. At another extreme, we show that although mouse major satellite repeats intrinsically encode well-defined nucleosome preferences, they have no unique nucleosome arrangement and can undergo a switch between two distinct types of nucleosome positioning.
Y1  - 2014
U6  - https://doi.org/10.1371/journal.pcbi.1003698
SN  - 1553-734X
SN  - 1553-7358
VL  - 10
IS  - 7
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Beurskens, Rainer
A1  - Helmich, Ingo
A1  - Rein, Robert
A1  - Bock, Otmar L.
T1  - Age-related changes in prefrontal activity during walking in dual-task situations: A fNIRS study
JF  - International journal of psychophysiology
N2  - Background: Previous studies suggest that the human gait is under control of higher-order cognitive processes, located in the frontal lobes, such that an age-related degradation of cognitive capabilities has a negative impact on gait.
 Results: Our behavioral data partly confirm previous accounts on higher dual-task costs in stepping parameters (i.e., decreased step duration) in old age, particularly with a visual task and negative dual-task cost (i.e., improved performance) during the verbal task in young adults. Functional imaging data revealed little change of prefrontal activation from single- to dual-task walking in young individuals. In the elderly, however, prefrontal activation substantially decreased during dual-task walking with a complex visual task.
 Conclusion: We interpret these findings as evidence for a shift of processing resources from the prefrontal cortex to other brain regions when seniors face the challenge of walking and concurrently executing a visually demanding task. (C) 2014 Elsevier B.V. All rights reserved.
KW  - fNIRS
KW  - Aging
KW  - Locomotion
KW  - Neural activation
KW  - Executive function
KW  - Dual-task walking
Y1  - 2014
U6  - https://doi.org/10.1016/j.ijpsycho.2014.03.005
SN  - 0167-8760
SN  - 1872-7697
VL  - 92
IS  - 3
SP  - 122
EP  - 128
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Bhatt, Kaushalendra M.
T1  - Microseisms and its impact on the marine-controlled source electromagnetic signal
JF  - Journal of geophysical research : Solid earth
N2  - The marine-controlled source electromagnetic method (mCSEM) is employed for studying the electrical characteristics and fluid contents of sedimentary reservoirs. However, the success rate of the method can be improved significantly by finding the sources of electromagnetic noise and addressing the challenge posed by them at larger offsets where the reservoir signal is often weak. I have studied the mCSEM data and reporting an electromagnetic noise. The strength of the noise is observed 1600 times stronger than the seafloor mCSEM signal at 0.1 Hz. Moreover, the noise and the transmitted mCSEM signals are found coherent in interstation recordings. These readings suggest the severity of the noise. The source investigation presuming the observed noise as an infragravity wave failed to match the response. Then, the role of microseisms is investigated. Microseism causes oscillation of the seafloor and produces electromagnetic disturbances by the dynamics of water. I have used various conditions for a proper discrimination of the noise as microseisms. This mechanism is clearly illustrated with the help of a conceptual diagram. The role of the directionality is part of the study, which is argued for having a significant role in the generation of microseisms. In this paper, a new algorithm is presented and is used for calculating the coherency. The algorithm helps in mapping the coherency value simultaneously in time and frequency domains.
KW  - microseisms
KW  - marine-controlled source electromagnetic method
KW  - spectrogram
KW  - coherency
KW  - Pierson-Moskowitz spectra
Y1  - 2014
U6  - https://doi.org/10.1002/2014JB011024
SN  - 2169-9313
SN  - 2169-9356
VL  - 119
IS  - 12
SP  - 8655
EP  - 8666
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Bianco, Pier Giorgio
A1  - Ketmaier, Valerio
T1  - A revision of the Rutilus complex from Mediterranean Europe with description of a new genus, Sarmarutilus, and a new species, Rutilus stoumboudae (Teleostei: Cyprinidae)
JF  - Zootaxa : an international journal of zootaxonomy ; a rapid international journal for animal taxonomists
N2  - By combining morphology, ecology, biology, and biogeography with the available molecular (sequence variation of the entire mitochondrial cytochrome b gene; cyt-b) and karyology data, the taxonomy of several species of the Rutilus complex inhabiting southern Europe is revised. Rutilus stoumboudae, new species, is described from Lake Volvi, Greece. It differs from Rutilus rutilus in possessing more total GR and less branched rays in both dorsal and anal fins and in its placement in the cyt-b based phylogeny of the genus. The resurrected genus Leucos Heckel, 1843 (type species Leucos aula, Bonaparte, 1841), which according to molecular data diverged from Rutilus more than 5 million years ago, during the Messinian salinity crisis, includes five species of small size, without spinous tubercles on scales and head in reproductive males, pharyngeal teeth formula 5-5, and all show a preference for still waters. Leucos aula is the Italian species endemic in the Padany-Venetian district: L. basak is widespread in Croatia, Albania, Montenegro and former Yugoslav Republic of Macedonia (FYROM); L. albus, recently described from Lake Skadar, Montenegro, is also found in rivers Moraca and Zeta (Montenegro). L. albus differs from L. basak, its closest relative, in having more scales on the LL and less anal-fin rays; L. panosi is endemic to the western-Greece district, and L. ylikiensis is endemic to lakes Yliki and Paralimni in eastern Greece (introduced in Lake Volvi). Among the nominal species examined, Rutilus karamani, R. ohridanus, R. prespensis and R. prespensis vukovici are all junior synonyms of Leucos basak. Rutilus vegariticus is definitively regarded as junior synonym for R. rutilus. Sarmarutilus n.gen. is a monotypic genus, with Sarmarutilus rubilio as the type species. According to phylogenetic data, Sarmarutilus rubilio is basal to a cluster of species that includes Leucos basak, L. albus, L. aula, L. panosi and L. ylikiensis. Sarmarutilus possibly evolved in pre-Messinian time, in the Lago Mare, entered the Mediterranean area during the Messinian Lago Mare phase of the Mediterranean Sea and survived only in the Tuscany-Latium district. This genus differs from Leucos in having large pearl organs on the central part of head and body scales in mature males and for the habitat preference, being a riverine-adapted species. It differs from Rutilus in pharyngeal teeth formula (5-5 in Sarmarutilus and 6-5 in Rutilus), size (small in Sarmarutilus and large in Rutilus) and for the preferential habitat (riverine vs. still water). Finally, lectotypes for Leucos basak, Leucos aula, and Sarmarutilus rubilio are designated.
KW  - Freshwater fish
KW  - Mediterranean Europe
KW  - Cyprinidae
KW  - genera Rutilus
KW  - Leucos
KW  - Sarmarutilus new genus
KW  - new species
Y1  - 2014
SN  - 1175-5326
SN  - 1175-5334
VL  - 3841
IS  - 3
SP  - 379
EP  - 402
PB  - Magnolia Press
CY  - Auckland
ER  - 
TY  - JOUR
A1  - Bickel, Samantha L.
A1  - Tang, Kam W.
A1  - Grossart, Hans-Peter
T1  - Structure and function of zooplankton-associated bacterial communities in a temperate estuary change more with time than with zooplankton species
JF  - Aquatic microbial ecology : international journal
N2  - Zooplankton support distinct bacterial communities in high concentrations relative to the surrounding water, but little is known about how the compositions and functionalities of these bacterial communities change through time in relation to environmental conditions. We conducted a year-long field study of bacterial communities associated with common zooplankton groups as well as free-living bacterial communities in the York River, a tributary of Chesapeake Bay. Bacterial community genetic fingerprints and their carbon substrate usage were examined by denaturing gradient gel electrophoresis (DGGE) of amplified 16S rDNA and by Biolog EcoPlates, respectively. Zooplankton-associated communities were genetically distinct from free-living bacterial communities but utilized a similar array of carbon substrates. On average, bacteria associated with different zooplankton groups were genetically more similar to each other within each month (65.4% similarity) than to bacterial communities of the same zooplankton group from different months (28 to 30% similarity), which suggests the importance of ambient environmental conditions in shaping resident zooplankton-associated bacterial communities. Monthly changes in carbon substrate utilization were less variable for zooplankton-associated bacteria than for free-living bacteria, suggesting that the zooplankton microhabitat is more stable than the surrounding water and supports specific bacterial groups in the otherwise unfavorable conditions in the water column.
KW  - Zooplankton
KW  - Bacterial communities
KW  - Carbon substrates
KW  - Biolog EcoPlates
KW  - York River
Y1  - 2014
U6  - https://doi.org/10.3354/ame01676
SN  - 0948-3055
SN  - 1616-1564
VL  - 72
IS  - 1
SP  - 1
EP  - 15
PB  - Institute of Mathematical Statistics
CY  - Oldendorf Luhe
ER  - 
TY  - JOUR
A1  - Bizic-Ionescu, Mina
A1  - Amann, Rudolf
A1  - Grossart, Hans-Peter
T1  - Massive regime shifts and high activity of heterotrophic bacteria in an ice-covered lake
JF  - PLoS one
N2  - In winter 2009/10, a sudden under-ice bloom of heterotrophic bacteria occurred in the seasonally ice-covered, temperate, deep, oligotrophic Lake Stechlin (Germany). Extraordinarily high bacterial abundance and biomass were fueled by the breakdown of a massive bloom of Aphanizomenon flos-aquae after ice formation. A reduction in light resulting from snow coverage exerted a pronounced physiological stress on the cyanobacteria. Consequently, these were rapidly colonized, leading to a sudden proliferation of attached and subsequently of free-living heterotrophic bacteria. Total bacterial protein production reached 201 mg C L-1 d(-1), ca. five times higher than spring-peak values that year. Fluorescence in situ hybridization and denaturing gradient gel electrophoresis at high temporal resolution showed pronounced changes in bacterial community structure coinciding with changes in the physiology of the cyanobacteria. Pyrosequencing of 16S rRNA genes revealed that during breakdown of the cyanobacterial population, the diversity of attached and free-living bacterial communities were reduced to a few dominant families. Some of these were not detectable during the early stages of the cyanobacterial bloom indicating that only specific, well adapted bacterial communities can colonize senescent cyanobacteria. Our study suggests that in winter, unlike commonly postulated, carbon rather than temperature is the limiting factor for bacterial growth. Frequent phytoplankton blooms in ice-covered systems highlight the need for year-round studies of aquatic ecosystems including the winter season to correctly understand element and energy cycling through aquatic food webs, particularly the microbial loop. On a global scale, such knowledge is required to determine climate change induced alterations in carbon budgets in polar and temperate aquatic systems.
Y1  - 2014
U6  - https://doi.org/10.1371/journal.pone.0113611
SN  - 1932-6203
VL  - 9
IS  - 11
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Blaese, Leif
T1  - Data mining for unidentified protein squences
JF  - Process design for natural scientists: an agile model-driven approach
N2  - Through the use of next generation sequencing (NGS) technology, a lot of newly sequenced organisms are now available. Annotating those genes is one of the most challenging tasks in sequence biology. Here, we present an automated workflow to find homologue proteins, annotate sequences according to function and create a three-dimensional model.
Y1  - 2014
SN  - 978-3-662-45005-5
SN  - 1865-0929
IS  - 500
SP  - 73
EP  - 87
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Blanchard, Gilles
A1  - Delattre, Sylvain
A1  - Roquain, Etienne
T1  - Testing over a continuum of null hypotheses with False Discovery Rate control
JF  - Bernoulli : official journal of the Bernoulli Society for Mathematical Statistics and Probability
N2  - We consider statistical hypothesis testing simultaneously over a fairly general, possibly uncountably infinite, set of null hypotheses, under the assumption that a suitable single test (and corresponding p-value) is known for each individual hypothesis. We extend to this setting the notion of false discovery rate (FDR) as a measure of type I error. Our main result studies specific procedures based on the observation of the p-value process. Control of the FDR at a nominal level is ensured either under arbitrary dependence of p-values, or under the assumption that the finite dimensional distributions of the p-value process have positive correlations of a specific type (weak PRDS). Both cases generalize existing results established in the finite setting. Its interest is demonstrated in several non-parametric examples: testing the mean/signal in a Gaussian white noise model, testing the intensity of a Poisson process and testing the c.d.f. of i.i.d. random variables.
KW  - continuous testing
KW  - false discovery rate
KW  - multiple testing
KW  - positive correlation
KW  - step-up
KW  - stochastic process
Y1  - 2014
U6  - https://doi.org/10.3150/12-BEJ488
SN  - 1350-7265
SN  - 1573-9759
VL  - 20
IS  - 1
SP  - 304
EP  - 333
PB  - International Statistical Institute
CY  - Voorburg
ER  - 
TY  - JOUR
A1  - Blanchard, Gilles
A1  - Dickhaus, Thorsten
A1  - Roquain, Etienne
A1  - Villers, Fanny
T1  - On least favorable configurations for step-up-down tests
JF  - Statistica Sinica
KW  - False discovery rate
KW  - least favorable configuration
KW  - multiple testing;
Y1  - 2014
U6  - https://doi.org/10.5705/ss.2011.205
SN  - 1017-0405
SN  - 1996-8507
VL  - 24
IS  - 1
SP  - 1
EP  - U31
PB  - Statistica Sinica, Institute of Statistical Science, Academia Sinica
CY  - Taipei
ER  - 
TY  - JOUR
A1  - Blankovsky, Yuval
T1  - Radical idea in talmudic literature
JF  - AJS review : The journal of the Association for Jewish Studies
N2  - The Babylonian Talmud (BT) attributes the idea of committing a transgression for the sake of God to R. Nahman b. Isaac (RNBI). RNBI's statement appears in two parallel sugyot in the BT (Nazir 23a; Horayot 10a). Each sugya has four textual witnesses. By comparing these textual witnesses, this paper will attempt to reconstruct the sugya's earlier (or, what some might term, original) dialectical form, from which the two familiar versions of the text in Nazir and Horayot evolved. This article reveals the specific ways in which, value-laden conceptualizations have a major impact on the Talmud's formulation, as we know it today.
Y1  - 2014
U6  - https://doi.org/10.1017/S0364009414000282
SN  - 0364-0094
SN  - 1475-4541
VL  - 38
IS  - 2
SP  - 321
EP  - 338
PB  - Cambridge Univ. Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Blankovsky, Yuval
T1  - A transgression for the sake of God—‘Averah Li-shmah
BT  - a tale of a radical idea in Talmudic literature
T2  - Postprints der Universität Potsdam : Philosophische Reihe
N2  - The Babylonian Talmud (BT) attributes the idea of committing a transgression for the sake of God to R. Nahman b. Isaac (RNBI). RNBI's statement appears in two parallel sugyot in the BT (Nazir 23a; Horayot 10a). Each sugya has four textual witnesses. By comparing these textual witnesses, this paper will attempt to reconstruct the sugya's earlier (or, what some might term, original) dialectical form, from which the two familiar versions of the text in Nazir and Horayot evolved. This article reveals the specific ways in which, value-laden conceptualizations have a major impact on the Talmud's formulation, as we know it today.
T3  - Zweitveröffentlichungen der Universität Potsdam : Philosophische Reihe - 160 
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-416156
SN  - 1866-8364
IS  - 160
SP  - 321
EP  - 338
ER  - 
TY  - JOUR
A1  - Bloethe, Jan H.
A1  - Munack, Henry
A1  - Korup, Oliver
A1  - Fuelling, Alexander
A1  - Garzanti, Eduardo
A1  - Resentini, Alberto
A1  - Kubik, Peter W.
T1  - Late Quaternary valley infill and dissection in the Indus River, western Tibetan Plateau margin
JF  - Quaternary science reviews : the international multidisciplinary research and review journal
N2  - The Indus, one of Earth's major rivers, drains large parts of the NW Himalaya and the Transhimalayan ranges that form part of the western Tibetan Plateau margin. In the western Himalayan syntaxis, where local topographic relief exceeds 7 km, the Indus has incised a steep bedrock gorge at rates of several mm yr(-1). Upstream, however, the upper Indus and its tributaries alternate between bedrock gorges and broad alluvial flats flanked by the Ladakh and Zanskar ranges. We review the late Quaternary valley history in this region with a focus on the confluence of the Indus and Zanskar Rivers, where vast alluvial terrace staircases and lake sediments record major episodes of aggradation and incision. New absolute dating of high-level fluvial terrace remnants using cosmogenic Be-10, optically and infrared stimulated luminescence (OSL, IRSL) indicates at least two phases of late Quaternary valley infilling. These phases commenced before similar to 200 ka and similar to 50-20 ka, judging from terrace treads stranded >150 m and similar to 30-40 m above modern river levels, respectively. Numerous stacks of lacustrine sediments that straddle the Indus River >200 km between the city of Leh and the confluence with the Shyok River share a distinct horizontal alignment. Constraints from IRSL samples of lacustrine sequences from the Leh-Spituk area reveal a protracted lake phase from >177 ka to 72 ka, locally accumulating >50-m thick deposits. In the absence of tectonic faulting, major lithological differences, and stream capture, we attribute the formation of this and other large lakes in the region to natural damming by large landslides, glaciers, and alluvial fans. The overall patchy landform age constraints from earlier studies can be reconciled by postulating a major deglacial control on sediment flux, valley infilling, and subsequent incision that has been modulated locally by backwater effects of natural damming. While comparison with Pleistocene monsoon proxies reveals no obvious correlation, a lateor post-glacial sediment pulse seems a more likely source of this widespread sedimentation that has partly buried the dissected bedrock topography. Overall, the long residence times of fluvial, alluvial and lacustrine deposits in the region (>500 ka) support previous studies, but remain striking given the dominantly steep slopes and deeply carved valleys that characterise this high-altitude mountain desert. Recalculated late Quaternary rates of fluvial bedrock incision in the Indus and Zanskar of 1.5 +/- 0.2 mm yr(-1) are at odds with the longevity of juxtaposed valley-fill deposits, unless a lack of decisive lateral fluvial erosion helps to preserve these late Pleistocene sedimentary archives. We conclude that alternating, similar to 10(4)-yr long, phases of massive infilling and incision have dominated the late Quaternary history of the Indus valley below the western Tibetan Plateau margin. (C) 2014 Elsevier Ltd. All rights reserved.
KW  - Himalaya
KW  - Indus
KW  - Valley fills
KW  - Glaciation
KW  - Erosion
KW  - Lake sediment
Y1  - 2014
U6  - https://doi.org/10.1016/j.quascirev.2014.04.011
SN  - 0277-3791
VL  - 94
SP  - 102
EP  - 119
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Bocedi, Greta
A1  - Zurell, Damaris
A1  - Reineking, Bjoern
A1  - Travis, Justin M. J.
T1  - Mechanistic modelling of animal dispersal offers new insights into range expansion dynamics across fragmented landscapes
JF  - Ecography : pattern and diversity in ecology ; research papers forum
Y1  - 2014
U6  - https://doi.org/10.1111/ecog.01041
SN  - 0906-7590
SN  - 1600-0587
VL  - 37
IS  - 12
SP  - 1240
EP  - 1253
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Boecker-Schlier, Regina
A1  - Holz, Nathalie E.
A1  - Buchmann, Arlette F.
A1  - Blomeyer, Dorothea
A1  - Plichta, Michael M.
A1  - Wolf, Isabella
A1  - Baumeister, Sarah
A1  - Meyer-Lindenberg, Andreas
A1  - Banaschewski, Tobias
A1  - Brandeis, Daniel
A1  - Laucht, Manfred
T1  - Impact of early life adversity on reward processing in young adults: EEG-fMRI results from a prospective study over 25 years
T2  - PLoS one
Y1  - 2014
U6  - https://doi.org/10.1371/journal.pone.0112155
SN  - 1932-6203
VL  - 9
IS  - 10
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Boecker-Schlier, Regina
A1  - Holz, Nathalie E.
A1  - Buchmann, Arlette F.
A1  - Blomeyer, Dorothea
A1  - Plichta, Michael M.
A1  - Wolf, Isabella
A1  - Baumeister, Sarah
A1  - Meyer-Lindenberg, Andreas
A1  - Banaschewski, Tobias
A1  - Brandeis, Daniel
A1  - Laucht, Manfred
T1  - Impact of early life adversity on reward processing in young adults: EEG-fMRI results from a prospective study over 25 years
JF  - PLoS one
N2  - Several lines of evidence have implicated the mesolimbic dopamine reward pathway in altered brain function resulting from exposure to early adversity. The present study examined the impact of early life adversity on different stages of neuronal reward processing later in life and their association with a related behavioral phenotype, i.e. attention deficit/hyperactivity disorder (ADHD). 162 healthy young adults (mean age = 24.4 years; 58% female) from an epidemiological cohort study followed since birth participated in a simultaneous EEG-fMRI study using a monetary incentive delay task. Early life adversity according to an early family adversity index (EFA) and lifetime ADHD symptoms were assessed using standardized parent interviews conducted at the offspring's age of 3 months and between 2 and 15 years, respectively. fMRI region-of-interest analysis revealed a significant effect of EFA during reward anticipation in reward-related areas (i.e. ventral striatum, putamen, thalamus), indicating decreased activation when EFA increased. EEG analysis demonstrated a similar effect for the contingent negative variation (CNV), with the CNV decreasing with the level of EFA. In contrast, during reward delivery, activation of the bilateral insula, right pallidum and bilateral putamen increased with EFA. There was a significant association of lifetime ADHD symptoms with lower activation in the left ventral striatum during reward anticipation and higher activation in the right insula during reward delivery. The present findings indicate a differential long-term impact of early life adversity on reward processing, implicating hyporesponsiveness during reward anticipation and hyperresponsiveness when receiving a reward. Moreover, a similar activation pattern related to lifetime ADHD suggests that the impact of early life stress on ADHD may possibly be mediated by a dysfunctional reward pathway.
Y1  - 2014
U6  - https://doi.org/10.1371/journal.pone.0104185
SN  - 1932-6203
VL  - 9
IS  - 8
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Boehm, Veronica
A1  - Hennemann, Anja
T1  - The evidential use of the spanish imperfect and the conditional in journalistic contexts
JF  - Studia neophilologica : a journal of Germanic and Romance languages and literature
Y1  - 2014
U6  - https://doi.org/10.1080/00393274.2014.933661
SN  - 0039-3274
SN  - 1651-2308
VL  - 86
IS  - 2
SP  - 183
EP  - 200
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Boehmer, Nadine
A1  - Hartmann, Tobias
A1  - Leimkühler, Silke
T1  - The chaperone FdsC for Rhodobacter capsulatus formate dehydrogenase binds the bis-molybdopterin guanine dinucleotide cofactor
JF  - FEBS letters : the journal for rapid publication of short reports in molecular biosciences
N2  - Molybdoenzymes are complex enzymes in which the molybdenum cofactor (Moco) is deeply buried in the enzyme. Most molybdoenzymes contain a specific chaperone for the insertion of Moco. For the formate dehydrogenase FdsGBA from Rhodobacter capsulatus the two chaperones FdsC and FdsD were identified to be essential for enzyme activity, but are not a subunit of the mature enzyme. Here, we purified and characterized the FdsC protein after heterologous expression in Escherichia coli. We were able to copurify FdsC with the bound Moco derivate bis-molybdopterin guanine dinucleotide. This cofactor successfully was used as a source to reconstitute the activity of molybdoenzymes.
 Structured summary of protein interactions:
 FdsC and FdsC bind by molecular sieving (View interaction)
 FdsD binds to RcMobA by surface plasmon resonance (View interaction)
 FdsC binds to RcMobA by surface plasmon resonance (View interaction)
 FdsC binds to FdsA by surface plasmon resonance (View interaction)
KW  - Molybdenum cofactor
KW  - L-cysteine desulfurase
KW  - Formate dehydrogenase
KW  - Chaperone
KW  - bis-MGD
Y1  - 2014
U6  - https://doi.org/10.1016/j.febslet.2013.12.033
SN  - 0014-5793
SN  - 1873-3468
VL  - 588
IS  - 4
SP  - 531
EP  - 537
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - GEN
A1  - Boese, Adrian Daniel
T1  - Assessment of coupled cluster theory and more approximate methods for Hydrogen Bonded Systems (vol 9, pg 4403, 2013)
T2  - Journal of chemical theory and computation
Y1  - 2014
U6  - https://doi.org/10.1021/ct500041j
SN  - 1549-9618
SN  - 1549-9626
VL  - 10
IS  - 2
SP  - 893
EP  - 893
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Boggio, Jose M. Chavez
A1  - Bodenmueller, D.
A1  - Fremberg, T.
A1  - Haynes, R.
A1  - Roth, Martin M.
A1  - Eisermann, R.
A1  - Lisker, M.
A1  - Zimmermann, L.
A1  - Boehm, Michael
T1  - Dispersion engineered silicon nitride waveguides by geometrical and refractive-index optimization
JF  - Journal of the Optical Society of America : B, Optical physics
N2  - Dispersion engineering in silicon nitride (SiXNY) waveguides is investigated through the optimization of the waveguide transversal dimensions and refractive indices in a multicladding arrangement. Ultraflat dispersion of -84.0 +/- 0.5 ps/nm/km between 1700 and 2440 nm and 1.5 +/- 3 ps/nm/km between 1670 and 2500 nm is numerically demonstrated. It is shown that typical refractive index fluctuations as well as dimension fluctuations during fabrication of the SiXNY waveguides are a limitation for obtaining ultraflat dispersion profiles. Single- and multicladding waveguides are fabricated and their dispersion profiles measured (over nearly 1000 nm) using a low-coherence frequency domain interferometric technique. By appropriate thickness optimization, the zero-dispersion wavelength is tuned over a large spectral range in single-and multicladding waveguides with small refractive index contrast (3%). A flat dispersion profile with +/- 3.2 ps/nm/km variation over 500 nm is obtained in a multicladding waveguide fabricated with a refractive index contrast of 37%. Finally, we generate a nearly three-octave supercontinuum in this dispersion flattened multicladding SiXNY waveguide. (C) 2014 Optical Society of America
Y1  - 2014
U6  - https://doi.org/10.1364/JOSAB.31.002846
SN  - 0740-3224
SN  - 1520-8540
VL  - 31
IS  - 11
SP  - 2846
EP  - 2857
PB  - Optical Society of America
CY  - Washington
ER  - 
TY  - JOUR
A1  - Boit, Alice
A1  - Gaedke, Ursula
T1  - Benchmarking successional progress in a quantitative food web
JF  - PLoS one
N2  - Central to ecology and ecosystem management, succession theory aims to mechanistically explain and predict the assembly and development of ecological communities. Yet processes at lower hierarchical levels, e. g. at the species and functional group level, are rarely mechanistically linked to the under-investigated system-level processes which drive changes in ecosystem properties and functioning and are comparable across ecosystems. As a model system for secondary succession, seasonal plankton succession during the growing season is readily observable and largely driven autogenically. We used a long-term dataset from large, deep Lake Constance comprising biomasses, auto-and heterotrophic production, food quality, functional diversity, and mass-balanced food webs of the energy and nutrient flows between functional guilds of plankton and partly fish. Extracting population-and system-level indices from this dataset, we tested current hypotheses about the directionality of successional progress which are rooted in ecosystem theory, the metabolic theory of ecology, quantitative food web theory, thermodynamics, and information theory. Our results indicate that successional progress in Lake Constance is quantifiable, passing through predictable stages. Mean body mass, functional diversity, predator-prey weight ratios, trophic positions, system residence times of carbon and nutrients, and the complexity of the energy flow patterns increased during succession. In contrast, both the mass-specific metabolic activity and the system export decreased, while the succession rate exhibited a bimodal pattern. The weighted connectance introduced here represents a suitable index for assessing the evenness and interconnectedness of energy flows during succession. Diverging from earlier predictions, ascendency and eco-exergy did not increase during succession. Linking aspects of functional diversity to metabolic theory and food web complexity, we reconcile previously disjoint bodies of ecological theory to form a complete picture of successional progress within a pelagic food web. This comprehensive synthesis may be used as a benchmark for quantifying successional progress in other ecosystems.
Y1  - 2014
U6  - https://doi.org/10.1371/journal.pone.0090404
SN  - 1932-6203
VL  - 9
IS  - 2
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Boll-Avetisyan, Natalie
A1  - Kager, Rene
T1  - OCP-Place in speech segmentation
JF  - Language and speech
N2  - OCP-Place, a cross-linguistically well-attested constraint against pairs of consonants with shared [place], is psychologically real. Studies have shown that the processing of words violating OCP-Place is inhibited. Functionalists assume that OCP arises as a consequence of low-level perception: a consonant following another with the same [place] cannot be faithfully perceived as an independent unit. If functionalist theories were correct, then lexical access would be inhibited if two homorganic consonants conjoin at word boundaries-a problem that can only be solved with lexical feedback.
 Here, we experimentally challenge the functional account by showing that OCP-Place can be used as a speech segmentation cue during pre-lexical processing without lexical feedback, and that the use relates to distributions in the input.
 In Experiment 1, native listeners of Dutch located word boundaries between two labials when segmenting an artificial language. This indicates a use of OCP-Labial as a segmentation cue, implying a full perception of both labials. Experiment 2 shows that segmentation performance cannot solely be explained by well-formedness intuitions. Experiment 3 shows that knowledge of OCP-Place depends on language-specific input: in Dutch, co-occurrences of labials are under-represented, but co-occurrences of coronals are not. Accordingly, Dutch listeners fail to use OCP-Coronal for segmentation.
KW  - Artificial language learning
KW  - OCP-Place
KW  - phonotactics
KW  - speech segmentation
KW  - pre-lexical processing
Y1  - 2014
U6  - https://doi.org/10.1177/0023830913508074
SN  - 0023-8309
SN  - 1756-6053
VL  - 57
IS  - 3
SP  - 394
EP  - 421
PB  - Sage Publ.
CY  - London
ER  - 
TY  - GEN
A1  - Bondü, Rebecca
A1  - Beier, Sophia
T1  - Two of a kind?
BT  - differences and similarities of attacks in schools and in institutes of higher education
T2  - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - School attacks are attracting increasing attention in aggression research. Recent systematic analyses provided new insights into offense and offender characteristics. Less is known about attacks in institutes of higher education (e.g., universities). It is therefore questionable whether the term “school attack” should be limited to institutions of general education or could be extended to institutions of higher education. Scientific literature is divided in distinguishing or unifying these two groups and reports similarities as well as differences. We researched 232 school attacks and 45 attacks in institutes of higher education throughout the world and conducted systematic comparisons between the two groups. The analyses yielded differences in offender (e.g., age, migration background) and offense characteristics (e.g., weapons, suicide rates), and some similarities (e.g., gender). Most differences can apparently be accounted for by offenders’ age and situational influences. We discuss the implications of our findings for future research and the development of preventative measures.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 391 
KW  - school  attack
KW  - IHE  attack
KW  - rampage
KW  - higher  education
KW  - characteristics
KW  - prevention
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-404199
IS  - 391
ER  - 
TY  - GEN
A1  - Bondü, Rebecca
A1  - Scheithauer, Herbert
T1  - Leaking and death-threats by students
BT  - a study in German schools
T2  - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - Leaking comprises observable behavior or statements that signal intentions of committing a violent offense and is considered an important warning sign for school shootings. School staff who are confronted with leaking have to assess its seriousness and react appropriately - a difficult task, because knowledge about leaking is sparse. The present study, therefore, examined how frequently leaking occurs in schools and how teachers identify leaking and respond to it. To achieve this aim, we informed teachers from eight schools in Germany about the definition of leaking and other warning signs and risk factors for school shootings in a one-hour information session. Teachers were then asked to report cases of leaking over a six- to nine-month period and to answer a questionnaire on leaking and its treatment after the information session and six to nine months later. Our results suggest that leaking is a relevant problem in German schools. Teachers mostly rated the information session positively and benefited in several aspects (e.g. reported more perceived courses of action or improved knowledge about leaking), but also expressed a constant need for support. Our findings highlight teachers' needs for further support and training and may be used in the planning of prevention measures for school shootings.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 388 
KW  - death-threats
KW  - leaking
KW  - prevention
KW  - school shooting
KW  - violence in schools
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-404121
IS  - 388
ER  - 
TY  - JOUR
A1  - Bondü, Rebecca
A1  - Scheithauer, Herbert
T1  - Leaking and death-threats by students: A study in German schools
JF  - School psychology international
N2  - Leaking comprises observable behavior or statements that signal intentions of committing a violent offense and is considered an important warning sign for school shootings. School staff who are confronted with leaking have to assess its seriousness and react appropriately - a difficult task, because knowledge about leaking is sparse. The present study, therefore, examined how frequently leaking occurs in schools and how teachers identify leaking and respond to it. To achieve this aim, we informed teachers from eight schools in Germany about the definition of leaking and other warning signs and risk factors for school shootings in a one-hour information session. Teachers were then asked to report cases of leaking over a six- to nine-month period and to answer a questionnaire on leaking and its treatment after the information session and six to nine months later. Our results suggest that leaking is a relevant problem in German schools. Teachers mostly rated the information session positively and benefited in several aspects (e.g. reported more perceived courses of action or improved knowledge about leaking), but also expressed a constant need for support. Our findings highlight teachers' needs for further support and training and may be used in the planning of prevention measures for school shootings.
KW  - Death-threats
KW  - leaking
KW  - prevention
KW  - school shooting
KW  - violence in schools
Y1  - 2014
U6  - https://doi.org/10.1177/0143034314552346
SN  - 0143-0343
SN  - 1461-7374
VL  - 35
IS  - 6
SP  - 592
EP  - 608
PB  - Sage Publ.
CY  - London
ER  - 
TY  - JOUR
A1  - Bonifacio, P.
A1  - Rahmani, H.
A1  - Whitmore, J. B.
A1  - Wendt, Martin
A1  - Centurion, Martin
A1  - Molaro, P.
A1  - Srianand, R.
A1  - Murphy, M. T.
A1  - Petitjean, P.
A1  - Agafonova, I. I.
A1  - Evans, T. M.
A1  - Levshakov, S. A.
A1  - Lopez, S.
A1  - Martins, C. J. A. P.
A1  - Reimers, D.
A1  - Vladilo, G.
T1  - Fundamental constants and high-resolution spectroscopy
JF  - Astronomische Nachrichten = Astronomical notes
KW  - atomic processes
KW  - cosmology: observations
KW  - elementary particles
KW  - line: formation
KW  - quasars: absorption lines
KW  - techniques: spectroscopic
Y1  - 2014
U6  - https://doi.org/10.1002/asna.201312005
SN  - 0004-6337
SN  - 1521-3994
VL  - 335
IS  - 1
SP  - 83
EP  - 91
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Bora, Sanjay Singh
A1  - Scherbaum, Frank
A1  - Kühn, Nicolas
A1  - Stafford, Peter
T1  - Fourier spectral- and duration models for the generation of response spectra adjustable to different source-, propagation-, and site conditions
JF  - Bulletin of earthquake engineering : official publication of the European Association for Earthquake Engineering
N2  - One of the major challenges related with the current practice in seismic hazard studies is the adjustment of empirical ground motion prediction equations (GMPEs) to different seismological environments. We believe that the key to accommodating differences in regional seismological attributes of a ground motion model lies in the Fourier spectrum. In the present study, we attempt to explore a new approach for the development of response spectral GMPEs, which is fully consistent with linear system theory when it comes to adjustment issues. This approach consists of developing empirical prediction equations for Fourier spectra and for a particular duration estimate of ground motion which is tuned to optimize the fit between response spectra obtained through the random vibration theory framework and the classical way. The presented analysis for the development of GMPEs is performed on the recently compiled reference database for seismic ground motion in Europe (RESORCE-2012). Although, the main motivation for the presented approach is the adjustability and the use of the corresponding model to generate data driven host-to-target conversions, even as a standalone response spectral model it compares reasonably well with the GMPEs of Ambraseys et al. (Bull Earthq Eng 3:1-53, 2005), Akkar and Bommer (Seismol Res Lett 81(2):195-206, 2010) and Akkar and Cagnan (Bull Seismol Soc Am 100(6):2978-2995, 2010).
KW  - Ground motion prediction equation
KW  - Fourier amplitude spectrum
KW  - Duration
KW  - Random vibration theory
KW  - Response Spectrum
Y1  - 2014
U6  - https://doi.org/10.1007/s10518-013-9482-z
SN  - 1570-761X
SN  - 1573-1456
VL  - 12
IS  - 1
SP  - 467
EP  - 493
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - THES
A1  - Borchardt, Sven
T1  - Rainfall, weathering and erosion
BT  - quantification of earth surface processes in Suguta Valley, northern Kenya, using multispectral and hyperspectral data
Y1  - 2014
ER  - 
TY  - JOUR
A1  - Borck, Rainald
T1  - Adieu Rabenmutter-culture, fertility, female labour supply, the gender wage gap and childcare
JF  - Journal of population economics
N2  - This paper studies the effect of cultural attitudes on childcare provision, fertility, female labour supply and the gender wage gap. Cross-country data show that fertility, female labour force participation and childcare provision are positively correlated with each other, while the gender wage gap seems to be negatively correlated with these variables. The paper presents a model with endogenous fertility, female labour supply and childcare choices driven by cultural attitudes which fits these facts. There may exist multiple equilibria: one with zero childcare provision, low fertility and female labour supply and high wage gap and one with high childcare provision, high fertility and female labour supply and low wage gap.
KW  - Cultural attitudes
KW  - Fertility
KW  - Female labour supply
KW  - Wage gap
KW  - Childcare
Y1  - 2014
U6  - https://doi.org/10.1007/s00148-013-0499-z
SN  - 0933-1433
SN  - 1432-1475
VL  - 27
IS  - 3
SP  - 739
EP  - 765
PB  - Springer
CY  - New York
ER  -