TY  - JOUR
A1  - Abdalla, H.
A1  - Abramowski, A.
A1  - Aharonian, Felix A.
A1  - Benkhali, F. Ait
A1  - Akhperjanian, A. G.
A1  - Andersson, T.
A1  - Anguener, E. O.
A1  - Arrieta, M.
A1  - Aubert, P.
A1  - Backes, M.
A1  - Balzer, A.
A1  - Barnard, M.
A1  - Becherini, Y.
A1  - Tjus, J. Becker
A1  - Berge, D.
A1  - Bernhard, S.
A1  - Bernlorhr, K.
A1  - Blackwell, R.
A1  - Bottcher, M.
A1  - Boisson, C.
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Bregeon, J.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Bulik, T.
A1  - Capasso, M.
A1  - Carr, J.
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chakraborty, N.
A1  - Chalme-Calvet, R.
A1  - Chaves, R. C. G.
A1  - Chen, A.
A1  - Chevalier, J.
A1  - Chretien, M.
A1  - Colafrancesco, S.
A1  - Cologna, G.
A1  - Condon, B.
A1  - Conrad, J.
A1  - Cui, Y.
A1  - Davids, I. D.
A1  - Decock, J.
A1  - Degrange, B.
A1  - Deil, C.
A1  - Devin, J.
A1  - deWilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Domainko, W.
A1  - Donath, A.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Edwards, T.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Ernenwein, J. -P.
A1  - Eschbach, S.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Fernandes, M. V.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Funk, S.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Giavitto, G.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Goyal, A.
A1  - Grondin, M. -H.
A1  - Hadasch, D.
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Hawkes, J.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hervet, O.
A1  - Hinton, J. A.
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holler, M.
A1  - Horns, D.
A1  - Ivascenko, A.
A1  - Jacholkowska, A.
A1  - Jamrozy, M.
A1  - Janiak, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jingo, M.
A1  - Jogler, T.
A1  - Jouvin, L.
A1  - Jung-Richardt, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kerszberg, D.
A1  - Khelifi, B.
A1  - Er, M. Kie Ff
A1  - King, J.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kolitzus, D.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Kraus, M.
A1  - Krayzel, F.
A1  - Kruger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lees, J. -P.
A1  - Lefaucheur, J.
A1  - Lefranc, V.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Leser, E.
A1  - Lohse, T.
A1  - Lorentz, M.
A1  - Liu, R.
A1  - Lopez-Coto, R.
A1  - Lypova, I.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - Meintjes, P. J.
A1  - Meyer, M.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Mora, K.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - de Naurois, M.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Oettl, S.
A1  - Ohm, S.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Padovani, M.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perennes, C.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poon, H.
A1  - Prokhorov, D.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Romoli, C.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Salek, D.
A1  - Sanchez, D. A.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schussler, F.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Settimo, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shilon, I.
A1  - Simoni, R.
A1  - Sol, H.
A1  - Spanier, F.
A1  - Spengler, G.
A1  - Spies, F.
A1  - Ert, Ff
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian Michael
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, I.
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tibaldo, L.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - Wagner, P.
A1  - Wagner, R. M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Woernlein, A.
A1  - Wouters, D.
A1  - Yang, R.
A1  - Zabalza, V.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zefi, F.
A1  - Ziegler, A.
A1  - Zywucka, N.
T1  - Characterizing the gamma-ray long-term variability of PKS2155 304 with HESS and Fermi-LAT
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Studying the temporal variability of BL Lac objects at the highest energies provides unique insights into the extreme physical processes occurring in relativistic jets and in the vicinity of super-massive black holes. To this end, the long-term variability of the BL Lac object PKS 2155 304 is analyzed in the high (HE, 100MeV < E < 300 GeV) and very high energy (VHE, E > 200 GeV) gamma-ray domain. Over the course of similar to 9 yr of H. E. S. S. observations the VHE light curve in the quiescent state is consistent with a log-normal behavior. The VHE variability in this state is well described by flicker noise (power-spectral-density index beta(VHE) = 1 .10(+ 0 : 10) (0 : 13)) on timescales larger than one day. An analysis of similar to 5.5 yr of HE Fermi-LAT data gives consistent results (beta(HE) = 1 : 20(+ 0 : 21) (0 : 23), on timescales larger than 10 days) compatible with the VHE findings. The HE and VHE power spectral densities show a scale invariance across the probed time ranges. A direct linear correlation between the VHE and HE fluxes could neither be excluded nor firmly established. These long-term-variability properties are discussed and compared to the red noise behavior (beta similar to 2) seen on shorter timescales during VHE-flaring states. The difference in power spectral noise behavior at VHE energies during quiescent and flaring states provides evidence that these states are influenced by different physical processes, while the compatibility of the HE and VHE long-term results is suggestive of a common physical link as it might be introduced by an underlying jet-disk connection.
KW  - galaxies: active
KW  - BL Lacertae objects: individual: PKS 2155-304
KW  - gamma rays: galaxies
KW  - galaxies: jets
KW  - galaxies: nuclei
KW  - radiation mechanisms: non-thermal
Y1  - 2017
U6  - https://doi.org/10.1051/0004-6361/201629419
SN  - 1432-0746
SN  - 0004-6361
VL  - 598
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Abramowski, Attila
A1  - Aharonian, Felix A.
A1  - Benkhali, Faical  Ait
A1  - Akhperjanian, A. G.
A1  - Andersson, T.
A1  - Anguner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arrieta, M.
A1  - Aubert, Pierre
A1  - Backes, Michael
A1  - Balzer, Arnim
A1  - Barnard, Michelle
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Berge, David
A1  - Bernhard, Sabrina
A1  - Bernlöhr, K.
A1  - Blackwell, R.
A1  - Böttcher, Markus
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bonnefoy, S.
A1  - Bordas, Pol
A1  - Bregeon, Johan
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bryan, Mark
A1  - Buechele, M.
A1  - Bulik, Tomasz
A1  - Capasso, M.
A1  - Carr, John
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chakraborty, N.
A1  - Chaves, Ryan C. G.
A1  - Chen, Andrew
A1  - Chevalier, J.
A1  - Coffaro, M.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Condon, B.
A1  - Conrad, Jan
A1  - Cui, Y.
A1  - Davids, I. D.
A1  - Decock, J.
A1  - Degrange, B.
A1  - Deil, C.
A1  - Devin, J.
A1  - de Wilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Domainko, W.
A1  - Donath, A.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Edwards, T.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Ernenwein, J. -P.
A1  - Eschbach, S.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Fernandes, M. V.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Funk, S.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Giavitto, G.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Goyal, A.
A1  - Grondin, M. -H.
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Hawkes, J.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holch, Tim Lukas
A1  - Holler, M.
A1  - Horns, D.
A1  - Ivascenko, A.
A1  - Iwasaki, H.
A1  - Jacholkowska, A.
A1  - Jamrozy, M.
A1  - Janiak, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jingo, M.
A1  - Jogler, T.
A1  - Jouvin, L.
A1  - Jung-Richardt, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Kerszberg, D.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kolitzus, D.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Kraus, M.
A1  - Kruger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lees, J. -P.
A1  - Lefaucheur, J.
A1  - Lefranc, V.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Leser, Eva
A1  - Lohse, T.
A1  - Lorentz, M.
A1  - Liu, R.
A1  - Lopez-Coto, R.
A1  - Lypova, I.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - Meintjes, P. J.
A1  - Meyer, M.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Mora, K.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Padovani, M.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perennes, C.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poon, H.
A1  - Prokhorov, D.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Richter, S.
A1  - Rieger, F.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Saito, S.
A1  - Salek, D.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schussler, F.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Settimo, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shilon, I.
A1  - Simoni, R.
A1  - Sol, H.
A1  - Spanier, F.
A1  - Spengler, G.
A1  - Spies, F.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Takahashi, T.
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tibaldo, L.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - Wagner, P.
A1  - Wagner, R. M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Woernlein, A.
A1  - Wouters, D.
A1  - Yang, R.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zefi, F.
A1  - Ziegler, A.
A1  - Zywucka, N.
T1  - Measurement of the EBL spectral energy distribution using the VHE gamma-ray spectra of HESS blazars
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Very high-energy gamma rays (VHE, E greater than or similar to 100 GeV) propagating over cosmological distances can interact with the low-energy photons of the extragalactic background light (EBL) and produce electron-positron pairs. The transparency of the Universe to VHE gamma rays is then directly related to the spectral energy distribution (SED) of the EBL. The observation of features in the VHE energy spectra of extragalactic sources allows the EBL to be measured, which otherwise is very difficult. An EBL model-independent measurement of the EBL SED with the H.E.S.S. array of Cherenkov telescopes is presented. It was obtained by extracting the EBL absorption signal from the reanalysis of high-quality spectra of blazars. From H.E.S.S. data alone the EBL signature is detected at a significance of 9.5 sigma, and the intensity of the EBL obtained in different spectral bands is presented together with the associated gamma-ray horizon.
KW  - gamma rays: galaxies
KW  - BL Lacertae objects: general
KW  - cosmic background radiation
KW  - infrared: diffuse background
Y1  - 2017
U6  - https://doi.org/10.1051/0004-6361/201731200
SN  - 1432-0746
VL  - 606
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Abramowski, Attila
A1  - Aharonian, Felix A.
A1  - Benkhali, Faical  Ait
A1  - Anguner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arrieta, M.
A1  - Aubert, Pierre
A1  - Backes, Michael
A1  - Balzer, Arnim
A1  - Barnard, Michelle
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Berge, David
A1  - Bernhard, Sabrina
A1  - Bernlöhr, K.
A1  - Blackwell, R.
A1  - Böttcher, Markus
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bonnefoy, S.
A1  - Bordas, Pol
A1  - Bregeon, Johan
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bryan, Mark
A1  - Buechele, M.
A1  - Bulik, Tomasz
A1  - Capasso, M.
A1  - Caroff, S.
A1  - Carosi, A.
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chakraborty, N.
A1  - Chaves, Ryan C. G.
A1  - Chen, Andrew
A1  - Chevalier, J.
A1  - Colafrancesco, Sergio
A1  - Condon, B.
A1  - Conrad, Jan
A1  - Davids, I. D.
A1  - Decock, J.
A1  - Deil, C.
A1  - Devin, J.
A1  - deWilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Donath, A.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Edwards, T.
A1  - Egberts, Kathrin
A1  - Emery, G.
A1  - Ernenwein, J. -P.
A1  - Eschbach, S.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Fernandes, M. V.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Funk, S.
A1  - Fuessling, M.
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gate, F.
A1  - Giavitto, G.
A1  - Giebels, B.
A1  - Glawion, D.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M. -H.
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Hawkes, J.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holch, Tim Lukas
A1  - Holler, M.
A1  - Horns, D.
A1  - Ivascenko, A.
A1  - Iwasaki, H.
A1  - Jacholkowska, A.
A1  - Jamrozy, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jingo, M.
A1  - Jouvin, L.
A1  - Jung-Richardt, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Kerszberg, D.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Kraus, M.
A1  - Kruer, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lees, J. -P.
A1  - Lefaucheur, J.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Leser, Eva
A1  - Lohse, T.
A1  - Lorentz, M.
A1  - Liu, R.
A1  - Lopez-Coto, R.
A1  - Lypova, I.
A1  - Malyshev, D.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - Meintjes, P. J.
A1  - Meyer, M.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Mora, K.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Ndiyavala, H.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Padovani, M.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perennes, C.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poireau, V.
A1  - Poon, H.
A1  - Prokhorov, D.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Rinchiuso, L.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Saito, S.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schussler, F.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Settimo, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shilon, I.
A1  - Shiningayamwe, K.
A1  - Simoni, R.
A1  - Sol, H.
A1  - Spanier, F.
A1  - Spir-Jacob, M.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steppa, Constantin Beverly
A1  - Sushch, Iurii
A1  - Takahashi, T.
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tibaldo, L.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsirou, M.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - Wagner, P.
A1  - Wagner, R. M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Woernlein, A.
A1  - Wouters, D.
A1  - Yang, R.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zefi, F.
A1  - Ziegler, A.
A1  - Zorn, J.
A1  - Zywucka, N.
T1  - TeV Gamma-Ray Observations of the Binary Neutron Star Merger GW170817 with HESS
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters
N2  - We search for high-energy gamma-ray emission from the binary neutron star merger GW170817 with the H.E.S.S. Imaging Air Cherenkov Telescopes. The observations presented here have been obtained starting only 5.3 hr after GW170817. The H.E.S.S. target selection identified regions of high probability to find a counterpart of the gravitational-wave event. The first of these regions contained the counterpart SSS17a that has been identified in the optical range several hours after our observations. We can therefore present the first data obtained by a ground-based pointing instrument on this object. A subsequent monitoring campaign with the H.E.S.S. telescopes extended over several days, covering timescales from 0.22 to 5.2 days and energy ranges between 270 GeV to 8.55 TeV. No significant gamma-ray emission has been found. The derived upper limits on the very-high-energy gamma-ray flux for the first time constrain non-thermal, high-energy emission following the merger of a confirmed binary neutron star system.
KW  - gamma-ray burst: individual (GRB 170817A)
KW  - gamma rays: general
KW  - gravitational waves
Y1  - 2017
U6  - https://doi.org/10.3847/2041-8213/aa97d2
SN  - 2041-8205
SN  - 2041-8213
VL  - 850
SP  - 628
EP  - 650
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Abeysekara, A. U.
A1  - Archambault, S.
A1  - Archer, A.
A1  - Benbow, W.
A1  - Bird, R.
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Cerruti, M.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Falcone, A.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Gillanders, G. H.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Huetten, M.
A1  - Hanna, D.
A1  - Hervet, O.
A1  - Holder, J.
A1  - Humensky, T. B.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kelley-Hoskins, N.
A1  - Kertzman, M.
A1  - Kieda, D.
A1  - Krause, M.
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Maier, G.
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Petrashyk, A.
A1  - Pohl, Martin
A1  - Popkow, A.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rulten, C.
A1  - Sadeh, I.
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Shahinyan, K.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Tyler, J.
A1  - Vassiliev, V. V.
A1  - Wakely, S. P.
A1  - Weiner, O. M.
A1  - Weinstein, A.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Zitzer, B.
T1  - Discovery of Very-high-energy Emission from RGB J2243+203 and Derivation of Its Redshift Upper Limit
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Supplement series
N2  - Very-high-energy (VHE; > 100 GeV) gamma-ray emission from the blazar RGB J2243+203 was discovered with the VERITAS Cherenkov telescope array, during the period between 2014 December 21 and 24. The VERITAS energy spectrum from this source can be fitted by a power law with a photon index of 4.6 +/- 0.5, and a flux normalization at 0.15 TeV of (6.3 +/- 1.1) x 10(-10) cm(-2) s(-1) TeV-1. The integrated Fermi-LAT flux from 1 to 100 GeV during the VERITAS detection is (4.1 +/- 0.8) x 10(-8) cm(-2) s(-1), which is an order of magnitude larger than the four-year-averaged flux in the same energy range reported in the 3FGL catalog, (4.0 +/- 0.1 x 10(-9) cm(-2) s(-1)). The detection with VERITAS triggered observations in the X-ray band with the Swift-XRT. However, due to scheduling constraints Swift-XRT observations were performed 67 hr after the VERITAS detection, rather than simultaneously with the VERITAS observations. The observed X-ray energy spectrum between 2 and 10 keV can be fitted with a power law with a spectral index of 2.7 +/- 0.2, and the integrated photon flux in the same energy band is (3.6 +/- 0.6) x 10(-13) cm(-2) s(-1). EBL-model-dependent upper limits of the blazar redshift have been derived. Depending on the EBL model used, the upper limit varies in the range from z < 0.9 to z < 1.1.
KW  - galaxies: individual (RGB J2243+203)
Y1  - 2017
U6  - https://doi.org/10.3847/1538-4365/aa8d76
SN  - 0067-0049
SN  - 1538-4365
VL  - 233
SP  - 1188
EP  - 1204
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Abeysekara, A. U.
A1  - Archambault, S.
A1  - Archer, A.
A1  - Benbow, Wystan
A1  - Bird, Ralph
A1  - Buchovecky, M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Byrum, K.
A1  - Cerruti, M.
A1  - Chen, X.
A1  - Ciupik, L.
A1  - Cui, W.
A1  - Dickinson, H. J.
A1  - Eisch, J. D.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Gillanders, G. H.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Hutten, M.
A1  - Hakansson, N.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Humensky, T. B.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kertzman, M.
A1  - Kieda, D.
A1  - Krause, M.
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Maier, G.
A1  - McArthur, S.
A1  - McCann, A.
A1  - Meagher, K.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nguyen, T.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Pelassa, V.
A1  - Pohl, Martin
A1  - Popkow, A.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rulten, C.
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Shahinyan, K.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Tucci, J. V.
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weiner, O. M.
A1  - Weinstein, A.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Fegan, S.
A1  - Giebels, B.
A1  - Horan, D.
A1  - Berdyugin, A.
A1  - Kuan, J.
A1  - Lindfors, E.
A1  - Nilsson, K.
A1  - Oksanen, A.
A1  - Prokoph, H.
A1  - Reinthal, R.
A1  - Takalo, L.
A1  - Zefi, F.
T1  - A Luminous and Isolated Gamma-Ray Flare from the Blazar B2 1215+30
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - B2 1215+30 is a BL-Lac-type blazar that was first detected at TeV energies by the MAGIC atmospheric Cherenkov telescopes and subsequently confirmed by the Very Energetic Radiation Imaging Telescope Array System (VERITAS) observatory with data collected between 2009 and 2012. In 2014 February 08, VERITAS detected a large-amplitude flare from B2. 1215+30 during routine monitoring observations of the blazar 1ES. 1218+304, located in the same field of view. The TeV flux reached 2.4 times the Crab Nebula flux with a variability timescale of <3.6 hr. Multiwavelength observations with Fermi-LAT, Swift, and the Tuorla Observatory revealed a correlated high GeV flux state and no significant optical counterpart to the flare, with a spectral energy distribution where the gamma-ray luminosity exceeds the synchrotron luminosity. When interpreted in the framework of a onezone leptonic model, the observed emission implies a high degree of beaming, with Doppler factor delta > 10, and an electron population with spectral index p < 2.3.
KW  - BL Lacertae objects: individual (B2 1215+30, VER J1217+301)
KW  - galaxies: active
KW  - galaxies: jets
KW  - galaxies: nuclei
KW  - gamma rays: galaxies
Y1  - 2017
U6  - https://doi.org/10.3847/1538-4357/836/2/205
SN  - 0004-637X
SN  - 1538-4357
VL  - 836
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Abouserie, Ahed
A1  - Zehbe, Kerstin
A1  - Metzner, Philipp
A1  - Kelling, Alexandra
A1  - Günter, Christina
A1  - Schilde, Uwe
A1  - Strauch, Peter
A1  - Körzdörfer, Thomas
A1  - Taubert, Andreas
T1  - Alkylpyridinium Tetrahalidometallate Ionic Liquids and Ionic Liquid Crystals: Insights into the Origin of Their Phase Behavior
JF  - European journal of inorganic chemistry : a journal of ChemPubSoc Europe
N2  - Six N-alkylpyridinium salts [CnPy](2)[MCl4] (n = 4 or 12 and M = Co, Cu, Zn) were synthesized, and their structure and thermal properties were studied. The [C4Py](2)[MCl4] compounds are monoclinic and crystallize in the space group P2(1)/n. The crystals of the longer chain analogues [C12Py](2)[MCl4] are triclinic and crystallize in the space group P (1) over bar. Above the melting temperature, all compounds are ionic liquids (ILs). The derivatives with the longer C12 chain exhibit liquid crystallinity and the shorter chain compounds only show a melting transition. Consistent with single-crystal analysis, electron paramagnetic resonance spectroscopy suggests that the [CuCl4](2-) ions in the Cu-based ILs have a distorted tetrahedral geometry.
KW  - Ionic liquids
KW  - Alkylpyridinium salts
KW  - Structure elucidation
KW  - Phase transitions
Y1  - 2017
U6  - https://doi.org/10.1002/ejic.201700826
SN  - 1434-1948
SN  - 1099-0682
SP  - 5640
EP  - 5649
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Abouserie, Ahed
A1  - Zehbe, Kerstin
A1  - Metzner, Philipp
A1  - Kelling, Alexandra
A1  - Günter, Christina
A1  - Schilde, Uwe
A1  - Strauch, Peter
A1  - Körzdörfer, Thomas
A1  - Taubert, Andreas
T1  - Alkylpyridinium Tetrahalidometallate Ionic Liquids and Ionic Liquid Crystals: Insights into the Origin of Their Phase Behavior
JF  - European journal of inorganic chemistry : a journal of ChemPubSoc Europe
N2  - Six N-alkylpyridinium salts [CnPy](2)[MCl4] (n = 4 or 12 and M = Co, Cu, Zn) were synthesized, and their structure and thermal properties were studied. The [C4Py](2)[MCl4] compounds are monoclinic and crystallize in the space group P2(1)/n. The crystals of the longer chain analogues [C12Py](2)[MCl4] are triclinic and crystallize in the space group P (1) over bar. Above the melting temperature, all compounds are ionic liquids (ILs). The derivatives with the longer C12 chain exhibit liquid crystallinity and the shorter chain compounds only show a melting transition. Consistent with single-crystal analysis, electron paramagnetic resonance spectroscopy suggests that the [CuCl4](2-) ions in the Cu-based ILs have a distorted tetrahedral geometry.
KW  - Ionic liquids
KW  - Alkylpyridinium salts
KW  - Structure elucidation
KW  - Phase transitions
Y1  - 2017
U6  - https://doi.org/10.1002/ejic.201700826
SN  - 1434-1948
SN  - 1099-0682
SP  - 5640
EP  - 5649
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Abrahamczyk, Stefan
A1  - Lozada Gobilard, Sissi Donna
A1  - Ackermann, Markus
A1  - Fischer, Eberhard
A1  - Krieger, Vera
A1  - Redling, Almut
A1  - Weigend, Maximilian
T1  - A question of data quality-Testing pollination syndromes in Balsaminaceae
JF  - PLoS one
N2  - Pollination syndromes and their predictive power regarding actual plant-animal interactions have been controversially discussed in the past. We investigate pollination syndromes in Balsaminaceae, utilizing quantitative respectively categorical data sets of flower morphometry, signal and reward traits for 86 species to test for the effect of different types of data on the test patterns retrieved. Cluster Analyses of the floral traits are used in combination with independent pollinator observations. Based on quantitative data we retrieve seven clusters, six of them corresponding to plausible pollination syndromes and one additional, well-supported cluster comprising highly divergent floral architectures. This latter cluster represents a non-syndrome of flowers not segregated by the specific data set here used. Conversely, using categorical data we obtained only a rudimentary resolution of pollination syndromes, in line with several earlier studies. The results underscore that the use of functional, exactly quanitified trait data has the power to retrieve pollination syndromes circumscribed by the specific data used. Data quality can, however, not be replaced by sheer data volume. With this caveat, it is possible to identify pollination syndromes from large datasets and to reliably extrapolate them for taxa for which direct observations are unavailable.
Y1  - 2017
U6  - https://doi.org/10.1371/journal.pone.0186125
SN  - 1932-6203
VL  - 12
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Acero, F.
A1  - Aloisio, R.
A1  - Amans, J.
A1  - Amato, Elena
A1  - Antonelli, L. A.
A1  - Aramo, C.
A1  - Armstrong, T.
A1  - Arqueros, F.
A1  - Asano, Katsuaki
A1  - Ashley, M.
A1  - Backes, M.
A1  - Balazs, C.
A1  - Balzer, A.
A1  - Bamba, Aya
A1  - Barkov, Maxim
A1  - Barrio, J. A.
A1  - Benbow, Wystan
A1  - Bernloehr, K.
A1  - Beshley, V.
A1  - Bigongiari, C.
A1  - Biland, A.
A1  - Bilinsky, A.
A1  - Bissaldi, Elisabetta
A1  - Biteau, J.
A1  - Blanch, O.
A1  - Blasi, P.
A1  - Blazek, J.
A1  - Boisson, C.
A1  - Bonanno, G.
A1  - Bonardi, A.
A1  - Bonavolonta, C.
A1  - Bonnoli, G.
A1  - Braiding, C.
A1  - Brau-Nogue, S.
A1  - Bregeon, J.
A1  - Brown, A. M.
A1  - Bugaev, V.
A1  - Bulgarelli, A.
A1  - Bulik, T.
A1  - Burton, Michael
A1  - Burtovoi, A.
A1  - Busetto, G.
A1  - Bottcher, M.
A1  - Cameron, R.
A1  - Capalbi, M.
A1  - Caproni, Anderson
A1  - Caraveo, P.
A1  - Carosi, R.
A1  - Cascone, E.
A1  - Cerruti, M.
A1  - Chaty, Sylvain
A1  - Chen, A.
A1  - Chen, X.
A1  - Chernyakova, M.
A1  - Chikawa, M.
A1  - Chudoba, J.
A1  - Cohen-Tanugi, J.
A1  - Colafrancesco, S.
A1  - Conforti, V.
A1  - Contreras, J. L.
A1  - Costa, A.
A1  - Cotter, G.
A1  - Covino, Stefano
A1  - Covone, G.
A1  - Cumani, P.
A1  - Cusumano, G.
A1  - Daniel, M.
A1  - Dazzi, F.
A1  - De Angelis, A.
A1  - De Cesare, G.
A1  - De Franco, A.
A1  - De Frondat, F.
A1  - Dal Pino, E. M. de Gouveia
A1  - De Lisio, C.
A1  - Lopez, R. de los Reyes
A1  - De Lotto, B.
A1  - de Naurois, M.
A1  - De Palma, F.
A1  - Del Santo, M.
A1  - Delgado, C.
A1  - della Volpe, D.
A1  - Di Girolamo, T.
A1  - Di Giulio, C.
A1  - Di Pierro, F.
A1  - Di Venere, L.
A1  - Doro, M.
A1  - Dournaux, J.
A1  - Dumas, D.
A1  - Dwarkadas, Vikram V.
A1  - Diaz, C.
A1  - Ebr, J.
A1  - Egberts, Kathrin
A1  - Einecke, S.
A1  - Elsaesser, D.
A1  - Eschbach, S.
A1  - Falceta-Goncalves, D.
A1  - Fasola, G.
A1  - Fedorova, E.
A1  - Fernandez-Barral, A.
A1  - Ferrand, Gilles
A1  - Fesquet, M.
A1  - Fiandrini, E.
A1  - Fiasson, A.
A1  - Filipovic, Miroslav D.
A1  - Fioretti, V.
A1  - Font, L.
A1  - Fontaine, Gilles
A1  - Franco, F. J.
A1  - Freixas Coromina, L.
A1  - Fujita, Yutaka
A1  - Fukui, Y.
A1  - Funk, S.
A1  - Forster, A.
A1  - Gadola, A.
A1  - Lopez, R. Garcia
A1  - Garczarczyk, M.
A1  - Giglietto, N.
A1  - Giordano, F.
A1  - Giuliani, A.
A1  - Glicenstein, J.
A1  - Gnatyk, R.
A1  - Goldoni, P.
A1  - Grabarczyk, T.
A1  - Graciani, R.
A1  - Graham, J.
A1  - Grandi, P.
A1  - Granot, Jonathan
A1  - Green, A. J.
A1  - Griffiths, S.
A1  - Gunji, S.
A1  - Hakobyan, H.
A1  - Hara, S.
A1  - Hassan, T.
A1  - Hayashida, M.
A1  - Heller, M.
A1  - Helo, J. C.
A1  - Hinton, J.
A1  - Hnatyk, B.
A1  - Huet, J.
A1  - Huetten, M.
A1  - Humensky, T. B.
A1  - Hussein, M.
A1  - Horandel, J.
A1  - Ikeno, Y.
A1  - Inada, T.
A1  - Inome, Y.
A1  - Inoue, S.
A1  - Inoue, T.
A1  - Inoue, Y.
A1  - Ioka, K.
A1  - Iori, Maurizio
A1  - Jacquemier, J.
A1  - Janecek, P.
A1  - Jankowsky, D.
A1  - Jung, I.
A1  - Kaaret, P.
A1  - Katagiri, H.
A1  - Kimeswenger, S.
A1  - Kimura, Shigeo S.
A1  - Knodlseder, J.
A1  - Koch, B.
A1  - Kocot, J.
A1  - Kohri, K.
A1  - Komin, N.
A1  - Konno, Y.
A1  - Kosack, K.
A1  - Koyama, S.
A1  - Kraus, Michaela
A1  - Kubo, Hidetoshi
A1  - Mezek, G. Kukec
A1  - Kushida, J.
A1  - La Palombara, N.
A1  - Lalik, K.
A1  - Lamanna, G.
A1  - Landt, H.
A1  - Lapington, J.
A1  - Laporte, P.
A1  - Lee, S.
A1  - Lees, J.
A1  - Lefaucheur, J.
A1  - Lenain, J. -P.
A1  - Leto, Giuseppe
A1  - Lindfors, E.
A1  - Lohse, T.
A1  - Lombardi, S.
A1  - Longo, F.
A1  - Lopez, M.
A1  - Lucarelli, F.
A1  - Luque-Escamilla, Pedro Luis
A1  - Lopez-Coto, R.
A1  - Maccarone, M. C.
A1  - Maier, G.
A1  - Malaguti, G.
A1  - Mandat, D.
A1  - Maneva, G.
A1  - Mangano, S.
A1  - Marcowith, Alexandre
A1  - Marti, J.
A1  - Martinez, M.
A1  - Martinez, G.
A1  - Masuda, S.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Melioli, Claudio
A1  - Mineo, T.
A1  - Mirabal, N.
A1  - Mizuno, T.
A1  - Moderski, R.
A1  - Mohammed, M.
A1  - Montaruli, T.
A1  - Moralejo, A.
A1  - Mori, K.
A1  - Morlino, G.
A1  - Morselli, A.
A1  - Moulin, Emmanuel
A1  - Mukherjee, R.
A1  - Mundell, C.
A1  - Muraishi, H.
A1  - Murase, Kohta
A1  - Nagataki, Shigehiro
A1  - Nagayoshi, T.
A1  - Naito, T.
A1  - Nakajima, D.
A1  - Nakamori, T.
A1  - Nemmen, R.
A1  - Niemiec, Jacek
A1  - Nieto, D.
A1  - Nievas-Rosillo, M.
A1  - Nikolajuk, M.
A1  - Nishijima, K.
A1  - Noda, K.
A1  - Nogues, L.
A1  - Nosek, D.
A1  - Novosyadlyj, B.
A1  - Nozaki, S.
A1  - Ohira, Yutaka
A1  - Ohishi, M.
A1  - Ohm, S.
A1  - Okumura, A.
A1  - Ong, R. A.
A1  - Orito, R.
A1  - Orlati, A.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Padovani, Marco
A1  - Palacio, J.
A1  - Palatka, M.
A1  - Paredes, Josep M.
A1  - Pavy, S.
A1  - Persic, M.
A1  - Petrucci, P.
A1  - Petruk, Oleh
A1  - Pisarski, A.
A1  - Pohl, Martin
A1  - Porcelli, A.
A1  - Prandini, E.
A1  - Prast, J.
A1  - Principe, G.
A1  - Prouza, M.
A1  - Pueschel, Elisa
A1  - Puelhofer, G.
A1  - Quirrenbach, A.
A1  - Rameez, M.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - Ribo, M.
A1  - Rico, J.
A1  - Rizi, V.
A1  - Rodriguez, J.
A1  - Fernandez, G. Rodriguez
A1  - Rodriguez Vazquez, J. J.
A1  - Romano, Patrizia
A1  - Romeo, G.
A1  - Rosado, J.
A1  - Rousselle, J.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Sadeh, I.
A1  - Safi-Harb, S.
A1  - Saito, T.
A1  - Sakaki, N.
A1  - Sanchez, D.
A1  - Sangiorgi, P.
A1  - Sano, H.
A1  - Santander, M.
A1  - Sarkar, S.
A1  - Sawada, M.
A1  - Schioppa, E. J.
A1  - Schoorlemmer, H.
A1  - Schovanek, P.
A1  - Schussler, F.
A1  - Sergijenko, O.
A1  - Servillat, M.
A1  - Shalchi, A.
A1  - Shellard, R. C.
A1  - Siejkowski, H.
A1  - Sillanpaa, A.
A1  - Simone, D.
A1  - Sliusar, V.
A1  - Sol, H.
A1  - Stanic, S.
A1  - Starling, R.
A1  - Stawarz, L.
A1  - Stefanik, S.
A1  - Stephan, M.
A1  - Stolarczyk, T.
A1  - Szanecki, M.
A1  - Szepieniec, T.
A1  - Tagliaferri, G.
A1  - Tajima, H.
A1  - Takahashi, M.
A1  - Takeda, J.
A1  - Tanaka, M.
A1  - Tanaka, S.
A1  - Tejedor, L. A.
A1  - Telezhinsky, Igor O.
A1  - Temnikov, P.
A1  - Terada, Y.
A1  - Tescaro, D.
A1  - Teshima, M.
A1  - Testa, V.
A1  - Thoudam, S.
A1  - Tokanai, F.
A1  - Torres, D. F.
A1  - Torresi, E.
A1  - Tosti, G.
A1  - Townsley, C.
A1  - Travnicek, P.
A1  - Trichard, C.
A1  - Trifoglio, M.
A1  - Tsujimoto, S.
A1  - Vagelli, V.
A1  - Vallania, P.
A1  - Valore, L.
A1  - van Driel, W.
A1  - van Eldik, C.
A1  - Vandenbroucke, Justin
A1  - Vassiliev, V.
A1  - Vecchi, M.
A1  - Vercellone, Stefano
A1  - Vergani, S.
A1  - Vigorito, C.
A1  - Vorobiov, S.
A1  - Vrastil, M.
A1  - Vazquez Acosta, M. L.
A1  - Wagner, S. J.
A1  - Wagner, R.
A1  - Wakely, S. P.
A1  - Walter, R.
A1  - Ward, J. E.
A1  - Watson, J. J.
A1  - Weinstein, A.
A1  - White, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Wilcox, P.
A1  - Williams, D. A.
A1  - Wischnewski, R.
A1  - Wojcik, P.
A1  - Yamamoto, T.
A1  - Yamamoto, H.
A1  - Yamazaki, Ryo
A1  - Yanagita, S.
A1  - Yang, L.
A1  - Yoshida, T.
A1  - Yoshida, M.
A1  - Yoshiike, S.
A1  - Yoshikoshi, T.
A1  - Zacharias, M.
A1  - Zampieri, L.
A1  - Zanin, R.
A1  - Zavrtanik, M.
A1  - Zavrtanik, D.
A1  - Zdziarski, A.
A1  - Zech, Alraune
A1  - Zechlin, Hannes
A1  - Zhdanov, V.
A1  - Ziegler, A.
A1  - Zorn, J.
T1  - Prospects for Cherenkov Telescope Array Observations of the Young Supernova Remnant RX J1713.7-3946
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We perform simulations for future Cherenkov Telescope Array (CTA) observations of RX J1713.7-3946, a young supernova remnant (SNR) and one of the brightest sources ever discovered in very high energy (VHE) gamma rays. Special attention is paid to exploring possible spatial (anti) correlations of gamma rays with emission at other wavelengths, in particular X-rays and CO/H I emission. We present a series of simulated images of RX J1713.7-3946 for CTA based on a set of observationally motivated models for the gamma-ray emission. In these models, VHE gamma rays produced by high-energy electrons are assumed to trace the nonthermal X-ray emission observed by XMM-Newton, whereas those originating from relativistic protons delineate the local gas distributions. The local atomic and molecular gas distributions are deduced by the NANTEN team from CO and H I observations. Our primary goal is to show how one can distinguish the emission mechanism(s) of the gamma rays (i.e., hadronic versus leptonic, or a mixture of the two) through information provided by their spatial distribution, spectra, and time variation. This work is the first attempt to quantitatively evaluate the capabilities of CTA to achieve various proposed scientific goals by observing this important cosmic particle accelerator.
KW  - cosmic rays
KW  - gamma rays: ISM
KW  - ISM: individual objects (RX J1713.7-3946, G347.3-0.5)
Y1  - 2017
U6  - https://doi.org/10.3847/1538-4357/aa6d67
SN  - 0004-637X
SN  - 1538-4357
VL  - 840
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Acevedo, Walter
A1  - De Wiljes, Jana
A1  - Reich, Sebastian
T1  - Second-order accurate ensemble transform particle filters
JF  - SIAM journal on scientific computing
N2  - Particle filters (also called sequential Monte Carlo methods) are widely used for state and parameter estimation problems in the context of nonlinear evolution equations. The recently proposed ensemble transform particle filter (ETPF) [S. Reich, SIAM T. Sci. Comput., 35, (2013), pp. A2013-A2014[ replaces the resampling step of a standard particle filter by a linear transformation which allows for a hybridization of particle filters with ensemble Kalman filters and renders the resulting hybrid filters applicable to spatially extended systems. However, the linear transformation step is computationally expensive and leads to an underestimation of the ensemble spread for small and moderate ensemble sizes. Here we address both of these shortcomings by developing second order accurate extensions of the ETPF. These extensions allow one in particular to replace the exact solution of a linear transport problem by its Sinkhorn approximation. It is also demonstrated that the nonlinear ensemble transform filter arises as a special case of our general framework. We illustrate the performance of the second-order accurate filters for the chaotic Lorenz-63 and Lorenz-96 models and a dynamic scene-viewing model. The numerical results for the Lorenz-63 and Lorenz-96 models demonstrate that significant accuracy improvements can be achieved in comparison to a standard ensemble Kalman filter and the ETPF for small to moderate ensemble sizes. The numerical results for the scene-viewing model reveal, on the other hand, that second-order corrections can lead to statistically inconsistent samples from the posterior parameter distribution.
KW  - Bayesian inference
KW  - data assimilation
KW  - particle filter
KW  - ensemble Kalman filter
KW  - Sinkhorn approximation
Y1  - 2017
U6  - https://doi.org/10.1137/16M1095184
SN  - 1064-8275
SN  - 1095-7197
SN  - 2168-3417
VL  - 39
IS  - 5
SP  - A1834
EP  - A1850
PB  - Society for Industrial and Applied Mathematics
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Acevedo, Walter
A1  - Fallah, Bijan
A1  - Reich, Sebastian
A1  - Cubasch, Ulrich
T1  - Assimilation of pseudo-tree-ring-width observations into an atmospheric general circulation model
JF  - Climate of the past : an interactive open access journal of the European Geosciences Union
N2  - Paleoclimate data assimilation (DA) is a promising technique to systematically combine the information from climate model simulations and proxy records. Here, we investigate the assimilation of tree-ring-width (TRW) chronologies into an atmospheric global climate model using ensemble Kalman filter (EnKF) techniques and a process-based tree-growth forward model as an observation operator. Our results, within a perfect-model experiment setting, indicate that the "online DA" approach did not outperform the "off-line" one, despite its considerable additional implementation complexity. On the other hand, it was observed that the nonlinear response of tree growth to surface temperature and soil moisture does deteriorate the operation of the time-averaged EnKF methodology. Moreover, for the first time we show that this skill loss appears significantly sensitive to the structure of the growth rate function, used to represent the principle of limiting factors (PLF) within the forward model. In general, our experiments showed that the error reduction achieved by assimilating pseudo-TRW chronologies is modulated by the magnitude of the yearly internal variability in themodel. This result might help the dendrochronology community to optimize their sampling efforts.
Y1  - 2017
U6  - https://doi.org/10.5194/cp-13-545-2017
SN  - 1814-9324
SN  - 1814-9332
VL  - 13
SP  - 545
EP  - 557
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Adam, Maurits
A1  - Reitenbach, Ivanina
A1  - Elsner, Birgit
T1  - Agency cues and 11-month-olds’ and adults’ anticipation of action goals
JF  - Cognitive Development
N2  - For the processing of goal-directed actions, some accounts emphasize the importance of experience with the action or the agent. Other accounts stress the importance of agency cues. We investigated the impact of agency cues on 11-month-olds’ and adults’ goal anticipation for a grasping-action performed by a mechanical claw. With an eyetracker, we measured anticipations in two conditions, where the claw was displayed either with or without agency cues. In two experiments, 11-month-olds were predictive when agency cues were present, but reactive when no agency cues were presented. Adults were predictive in both conditions. Furthermore, 11-month-olds rapidly learned to predict the goal in the agency condition, but not in the mechanical condition. Adults’ predictions did not change across trials in the agency condition, but decelerated in the mechanical condition. Thus, agency cues and own action experience are important for infants’ and adults’ online processing of goal-directed actions by non-human agents.
KW  - Infants
KW  - Eyetracking
KW  - Action processing
KW  - Anticipatory gaze shifts
KW  - Agency
Y1  - 2017
U6  - https://doi.org/10.1016/j.cogdev.2017.02.008
SN  - 0885-2014
SN  - 1879-226X
VL  - 43
SP  - 37
EP  - 48
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Adani, Flavia
A1  - Stegenwallner-Schutz, Maja Henny Katherine
A1  - Niesel, Talea
T1  - The Peaceful Co-existence of Input Frequency and Structural Intervention Effects on the Comprehension of Complex Sentences in German-Speaking Children
JF  - Frontiers in psychology
N2  - The predictions of two contrasting approaches to the acquisition of transitive relative clauses were tested within the same groups of German-speaking participants aged from 3 to 5 years old. The input frequency approach predicts that object relative clauses with inanimate heads (e.g., the pullover that the man is scratching) are comprehended earlier and more accurately than those with an animate head (e.g., the man that the boy is scratching). In contrast, the structural intervention approach predicts that object relative clauses with two full NP arguments mismatching in number (e.g., the man that the boys are scratching) are comprehended earlier and more accurately than those with number-matching NPs (e.g., the man that the boy is scratching). These approaches were tested in two steps. First, we ran a corpus analysis to ensure that object relative clauses with number-mismatching NPs are not more frequent than object relative clauses with number-matching NPs in child directed speech. Next, the comprehension of these structures was tested experimentally in 3-, 4-, and 5-year-olds respectively by means of a color naming task. By comparing the predictions of the two approaches within the same participant groups, we were able to uncover that the effects predicted by the input frequency and by the structural intervention approaches co-exist and that they both influence the performance of children on transitive relative clauses, but in a manner that is modulated by age. These results reveal a sensitivity to animacy mismatch already being demonstrated by 3-year-olds and show that animacy is initially deployed more reliably than number to interpret relative clauses correctly. In all age groups, the animacy mismatch appears to explain the performance of children, thus, showing that the comprehension of frequent object relative clauses is enhanced compared to the other conditions. Starting with 4-year-olds but especially in 5-year-olds, the number mismatch supported comprehension-a facilitation that is unlikely to be driven by input frequency. Once children fine-tune their sensitivity to verb agreement information around the age of four, they are also able to deploy number marking to overcome the intervention effects. This study highlights the importance of testing experimentally contrasting theoretical approaches in order to characterize the multifaceted, developmental nature of language acquisition.
KW  - relative clauses
KW  - sentence comprehension
KW  - input frequency
KW  - number
KW  - animacy
KW  - language acquisition
KW  - German
Y1  - 2017
U6  - https://doi.org/10.3389/fpsyg.2017.01590
SN  - 1664-1078
VL  - 8
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Adani, Flavia
A1  - Stegenwallner-Schütz, Maja Henny Katherine
A1  - Niesel, Talea
T1  - The Peaceful Co-existence of Input Frequency and Structural Intervention Effects on the Comprehension of Complex Sentences in German-Speaking Children
JF  - Frontiers in psychology
N2  - The predictions of two contrasting approaches to the acquisition of transitive relative clauses were tested within the same groups of German-speaking participants aged from 3 to 5 years old. The input frequency approach predicts that object relative clauses with inanimate heads (e.g., the pullover that the man is scratching) are comprehended earlier and more accurately than those with an animate head (e.g., the man that the boy is scratching). In contrast, the structural intervention approach predicts that object relative clauses with two full NP arguments mismatching in number (e.g., the man that the boys are scratching) are comprehended earlier and more accurately than those with number-matching NPs (e.g., the man that the boy is scratching). These approaches were tested in two steps. First, we ran a corpus analysis to ensure that object relative clauses with number-mismatching NPs are not more frequent than object relative clauses with number-matching NPs in child directed speech. Next, the comprehension of these structures was tested experimentally in 3-, 4-, and 5-year-olds respectively by means of a color naming task. By comparing the predictions of the two approaches within the same participant groups, we were able to uncover that the effects predicted by the input frequency and by the structural intervention approaches co-exist and that they both influence the performance of children on transitive relative clauses, but in a manner that is modulated by age. These results reveal a sensitivity to animacy mismatch already being demonstrated by 3-year-olds and show that animacy is initially deployed more reliably than number to interpret relative clauses correctly. In all age groups, the animacy mismatch appears to explain the performance of children, thus, showing that the comprehension of frequent object relative clauses is enhanced compared to the other conditions. Starting with 4-year-olds but especially in 5-year-olds, the number mismatch supported comprehension—a facilitation that is unlikely to be driven by input frequency. Once children fine-tune their sensitivity to verb agreement information around the age of four, they are also able to deploy number marking to overcome the intervention effects. This study highlights the importance of testing experimentally contrasting theoretical approaches in order to characterize the multifaceted, developmental nature of language acquisition.
KW  - relative clauses
KW  - sentence comprehension
KW  - input frequency
KW  - number
KW  - animacy
KW  - language acquisition
KW  - German
Y1  - 2017
U6  - https://doi.org/10.3389/fpsyg.2017.01590
SN  - 1664-1078
VL  - 8
SP  - 1
EP  - 11
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Adebayo, Segun Emmanuel
A1  - Hashim, Norhashila
A1  - Hass, Roland
A1  - Reich, Oliver
A1  - Regen, Christian
A1  - Münzberg, Marvin
A1  - Abdan, Khalina
A1  - Hanafi, Marsyita
A1  - Zude-Sasse, Manuela
T1  - Using absorption and reduced scattering coefficients for non-destructive analyses of fruit flesh firmness and soluble solids content in pear
JF  - Postharvest Biology and Technology
N2  - Quality attributes of fruit determine its acceptability by the retailer and consumer. The objective of this work was to investigate the potential of absorption (μa) and reduced scattering (μs’) coefficients of European pear to analyze its fruit flesh firmness and soluble solids content (SSC). The absolute reference values, μa* (cm−1) and μs’* (cm−1), of pear were invasively measured, employing multi-spectral photon density wave (PDW) spectroscopy at preselected wavelengths of 515, 690, and 940 nm considering two batches of unripe and overripe fruit. On eight measuring dates during fruit development, μa and μs’ were analyzed non-destructively by means of laser light backscattering imaging (LLBI) at similar wavelengths of 532, 660, and 830 nm by means of fitting according to Farrell’s diffusion theory, using fix reference values of either μa* or μs’*. Both, the μa* and the μa as well as μs’* and μs’ showed similar trends. Considering the non-destructively measured data during fruit development, μa at 660 nm decreased 91 till 141 days after full bloom (dafb) from 1.49 cm−1 to 0.74 cm−1 due to chlorophyll degradation. At 830 nm, μa only slightly decreased from 0.41 cm−1 to 0.35 cm−1. The μs’ at all wavelengths revealed a decreasing trend as the fruit developed. The difference measured at 532 nm was most pronounced decreasing from 24 cm−1 to 10 cm−1, while at 660 nm and 830 nm values decreased from 15 cm−1 to 13 cm−1 and from 10 cm−1 to 8 cm−1, respectively. When building calibration models with partial least-squares regression analysis on the optical properties for non-destructive analysis of the fruit SSC, μa at 532 nm and 830 nm resulted in a correlation coefficient of R = 0.66, however, showing high measuring uncertainty. The combination of all three wavelengths gave an enhanced, encouraging R = 0.89 for firmness analysis using μs’ in the freshly picked fruit.
KW  - Absorption
KW  - Non-destructive
KW  - Pear
KW  - Quality
KW  - Scattering
Y1  - 2017
U6  - https://doi.org/10.1016/j.postharvbio.2017.04.004
SN  - 0925-5214
SN  - 1873-2356
VL  - 130
SP  - 56
EP  - 63
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Adelt, Anne
A1  - Stadie, Nicole
A1  - Lassotta, Romy
A1  - Adani, Flavia
A1  - Burchert, Frank
T1  - Feature dissimilarities in the processing of German relative clauses in aphasia
JF  - Journal of neurolinguistics : an international journal for the study of brain function in language behavior and experience
N2  - The cross-linguistic finding of greater demands in processing object relatives as compared to subject relatives in individuals with aphasia and non-brain-damaged speakers has been explained within the Relativized Minimality approach. Based on this account, the asymmetry is attributed to an element intervening between the moved element and its extraction site in object relatives, but not in subject relatives. Moreover, it has been proposed that processing of object relatives is facilitated if the intervening and the moved elements differ in their internal feature structure. The present study investigates these predictions in German-speaking individuals with aphasia and a group of control participants by combining the visual world eye-tracking methodology with an auditory referent identification task. Our results provide support for the Relativized Minimality approach. Particularly, the degree of featural distinctness was shown to modulate the occurrence of the effects in aphasia. We claim that, due to reduced processing capacities, individuals with aphasia need a higher degree of featural dissimilarity to distinguish the moved from the intervening element in object relatives to overcome their syntactic deficit. (C) 2017 Elsevier Ltd. All rights reserved.
KW  - Aphasia
KW  - Relative clauses
KW  - Relativized Minimality
KW  - Sentence processing
KW  - Morpho-syntactic features
KW  - Eye tracking
Y1  - 2017
U6  - https://doi.org/10.1016/j.jneuroling.2017.01.002
SN  - 0911-6044
VL  - 44
SP  - 17
EP  - 37
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Agarwal, Ankit
A1  - Marwan, Norbert
A1  - Maheswaran, Rathinasamy
A1  - Merz, Bruno
A1  - Kurths, Jürgen
T1  - Multi-scale event synchronization analysis for unravelling climate processes: a wavelet-based approach
JF  - Nonlinear processes in geophysics
N2  - The temporal dynamics of climate processes are spread across different timescales and, as such, the study of these processes at only one selected timescale might not reveal the complete mechanisms and interactions within and between the (sub-) processes. To capture the non-linear interactions between climatic events, the method of event synchronization has found increasing attention recently. The main drawback with the present estimation of event synchronization is its restriction to analysing the time series at one reference timescale only. The study of event synchronization at multiple scales would be of great interest to comprehend the dynamics of the investigated climate processes. In this paper, the wavelet-based multi-scale event synchronization (MSES) method is proposed by combining the wavelet transform and event synchronization. Wavelets are used extensively to comprehend multi-scale processes and the dynamics of processes across various timescales. The proposed method allows the study of spatio-temporal patterns across different timescales. The method is tested on synthetic and real-world time series in order to check its replicability and applicability. The results indicate that MSES is able to capture relationships that exist between processes at different timescales.
Y1  - 2017
U6  - https://doi.org/10.5194/npg-24-599-2017
SN  - 1023-5809
VL  - 24
SP  - 599
EP  - 611
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Ahmed, Muhammad N.
A1  - Reyna-Gonzalez, Emmanuel
A1  - Schmid, Bianca
A1  - Wiebach, Vincent
A1  - Suessmuth, Roderich D.
A1  - Dittmann, Elke
A1  - Fewer, David P.
T1  - Phylogenomic Analysis of the Microviridin Biosynthetic Pathway Coupled with Targeted Chemo-Enzymatic Synthesis Yields Potent Protease Inhibitors
JF  - ACS chemical biology
N2  - Natural products and their semisynthetic derivatives are an important source of drugs for the pharmaceutical industry. Bacteria are prolific producers of natural products and encode a vast diversity of natural product biosynthetic gene clusters. However, much of this diversity is inaccessible to natural product discovery. Here, we use a combination of phylogenomic analysis of the microviridin biosynthetic pathway and chemo-enzymatic synthesis of bioinformatically predicted microviridins to yield new protease inhibitors. Phylogenomic analysis demonstrated that microviridin biosynthetic gene clusters occur across the bacterial domain and encode three distinct subtypes of precursor peptides. Our analysis shed light on the evolution of microviridin biosynthesis and enabled prioritization of their chemo-enzymatic production. Targeted one-pot synthesis of four microviridins encoded by the cyanobacterium Cyanothece sp. PCC 7822 identified a set of novel and potent serine protease inhibitors, the most active of which had an IC50 value of 21.5 nM. This study advances the genome mining techniques available for natural product discovery and obviates the need to culture bacteria.
Y1  - 2017
U6  - https://doi.org/10.1021/acschembio.7b00124
SN  - 1554-8929
SN  - 1554-8937
VL  - 12
SP  - 1538
EP  - 1546
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Ahnen, M. L.
A1  - Ansoldi, S.
A1  - Antonelli, L. A.
A1  - Antoranz, P.
A1  - Babic, A.
A1  - Banerjee, B.
A1  - Bangale, P.
A1  - de Almeida, U. Barres
A1  - Barrio, J. A.
A1  - Gonzalez, J. Becerra
A1  - Bednarek, W.
A1  - Bernardini, E.
A1  - Berti, A.
A1  - Biasuzzi, B.
A1  - Biland, A.
A1  - Blanch, O.
A1  - Bonnefoy, S.
A1  - Bonnoli, G.
A1  - Borracci, F.
A1  - Bretz, T.
A1  - Buson, S.
A1  - Carosi, A.
A1  - Chatterjee, A.
A1  - Clavero, R.
A1  - Colin, P.
A1  - Colombo, E.
A1  - Contreras, J. L.
A1  - Cortina, J.
A1  - Covino, S.
A1  - Da Vela, P.
A1  - Dazzi, F.
A1  - De Angelis, A.
A1  - De Lotto, B.
A1  - Wilhelmi, E. de Ona
A1  - Di Pierro, F.
A1  - Doert, M.
A1  - Dominguez, A.
A1  - Prester, D. Dominis
A1  - Dorner, D.
A1  - Doro, M.
A1  - Einecke, S.
A1  - Glawion, D. Eisenacher
A1  - Elsaesser, D.
A1  - Engelkemeier, M.
A1  - Ramazani, V. Fallah
A1  - Fernandez-Barral, A.
A1  - Fidalgo, D.
A1  - Fonseca, M. V.
A1  - Font, L.
A1  - Frantzen, K.
A1  - Fruck, C.
A1  - Galindo, D.
A1  - Lopez, R. J. Garcia
A1  - Garczarczyk, M.
A1  - Terrats, D. Garrido
A1  - Gaug, M.
A1  - Giammaria, P.
A1  - Godinovic, N.
A1  - Gonzalez Munoz, A.
A1  - Gora, D.
A1  - Guberman, D.
A1  - Hadasch, D.
A1  - Hahn, A.
A1  - Hanabata, Y.
A1  - Hayashida, M.
A1  - Herrera, J.
A1  - Hose, J.
A1  - Hrupec, D.
A1  - Hughes, G.
A1  - Idec, W.
A1  - Kodani, K.
A1  - Konno, Y.
A1  - Kubo, H.
A1  - Kushida, J.
A1  - La Barbera, A.
A1  - Lelas, D.
A1  - Lindfors, E.
A1  - Lombardi, S.
A1  - Longo, F.
A1  - Lopez, M.
A1  - Lopez-Coto, R.
A1  - Majumdar, P.
A1  - Makariev, M.
A1  - Mallot, K.
A1  - Maneva, G.
A1  - Manganaro, M.
A1  - Mannheim, K.
A1  - Maraschi, L.
A1  - Marcote, B.
A1  - Mariotti, M.
A1  - Martinez, M.
A1  - Mazin, D.
A1  - Menzel, U.
A1  - Miranda, J. M.
A1  - Mirzoyan, R.
A1  - Moralejo, A.
A1  - Moretti, E.
A1  - Nakajima, D.
A1  - Neustroev, V.
A1  - Niedzwiecki, A.
A1  - Rosillo, M. Nievas
A1  - Nilsson, K.
A1  - Nishijima, K.
A1  - Noda, K.
A1  - Nogues, L.
A1  - Overkemping, A.
A1  - Paiano, S.
A1  - Palacio, J.
A1  - Palatiello, M.
A1  - Paneque, D.
A1  - Paoletti, R.
A1  - Paredes, J. M.
A1  - Paredes-Fortuny, X.
A1  - Pedaletti, G.
A1  - Peresano, M.
A1  - Perri, L.
A1  - Persic, M.
A1  - Poutanen, J.
A1  - Moroni, P. G. Prada
A1  - Prandini, E.
A1  - Puljak, I.
A1  - Reichardt, I.
A1  - Rhode, W.
A1  - Ribo, M.
A1  - Rico, J.
A1  - Rodriguez Garcia, J.
A1  - Saito, T.
A1  - Satalecka, K.
A1  - Schroder, S.
A1  - Schultz, C.
A1  - Schweizer, T.
A1  - Shore, S. N.
A1  - Sillanpaa, A.
A1  - Sitarek, J.
A1  - Snidaric, I.
A1  - Sobczynska, D.
A1  - Stamerra, A.
A1  - Steinbring, T.
A1  - Strzys, M.
A1  - Suric, T.
A1  - Takalo, L.
A1  - Tavecchio, F.
A1  - Temnikov, P.
A1  - Terzic, T.
A1  - Tescaro, D.
A1  - Teshima, M.
A1  - Thaele, J.
A1  - Torres, D. F.
A1  - Toyama, T.
A1  - Treves, A.
A1  - Vanzo, G.
A1  - Verguilov, V.
A1  - Vovk, I.
A1  - Ward, J. E.
A1  - Will, M.
A1  - Wu, M. H.
A1  - Zanin, R.
A1  - Abeysekara, A. U.
A1  - Archambault, S.
A1  - Archer, A.
A1  - Benbow, W.
A1  - Bird, R.
A1  - Buchovecky, M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Dickinson, H. J.
A1  - Falcone, A.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Flinders, A.
A1  - Fortson, L.
A1  - Gillanders, G. H.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Huetten, M.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Humensky, T. B.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kelley-Hoskins, N.
A1  - Kertzman, M.
A1  - Kieda, D.
A1  - Krause, M.
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - Maier, G.
A1  - McCann, A.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, N.
A1  - Park, N.
A1  - Perkins, J.
A1  - Pichel, A.
A1  - Pohl, M.
A1  - Popkow, A.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rovero, A. C.
A1  - Rulten, C.
A1  - Sadeh, I.
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Shahinyan, K.
A1  - Telezhinsky, Igor O.
A1  - Tucci, J. V.
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Zitzer, B.
A1  - Razzaque, S.
A1  - Villata, M.
A1  - Raiteri, C. M.
A1  - Aller, H. D.
A1  - Aller, M. F.
A1  - Larionov, V. M.
A1  - Arkharov, A. A.
A1  - Blinov, D. A.
A1  - Efimova, N. V.
A1  - Grishina, T. S.
A1  - Hagen-Thorn, V. A.
A1  - Kopatskaya, E. N.
A1  - Larionova, L. V.
A1  - Larionova, E. G.
A1  - Morozova, D. A.
A1  - Troitsky, I. S.
A1  - Ligustri, R.
A1  - Calcidese, P.
A1  - Berdyugin, A.
A1  - Kurtanidze, O. M.
A1  - Nikolashvili, M. G.
A1  - Kimeridze, G. N.
A1  - Sigua, L. A.
A1  - Kurtanidze, S. O.
A1  - Chigladze, R. A.
A1  - Chen, W. P.
A1  - Koptelova, E.
A1  - Sakamoto, T.
A1  - Sadun, A. C.
A1  - Moody, J. W.
A1  - Pace, C.
A1  - Pearson, R.
A1  - Yatsu, Y.
A1  - Mori, Y.
A1  - Carraminyana, A.
A1  - Carrasco, L.
A1  - de la Fuente, E.
A1  - Norris, J. P.
A1  - Smith, P. S.
A1  - Wehrle, A.
A1  - Gurwell, M. A.
A1  - Zook, A.
A1  - Pagani, C.
A1  - Perri, M.
A1  - Capalbi, M.
A1  - Cesarini, A.
A1  - Krimm, H. A.
A1  - Kovalev, Y. Y.
A1  - Kovalev, Yu. A.
A1  - Ros, E.
A1  - Pushkarev, A. B.
A1  - Lister, M. L.
A1  - Sokolovsky, K. V.
A1  - Kadler, M.
A1  - Piner, G.
A1  - Lahteenmaki, A.
A1  - Tornikoski, M.
A1  - Angelakis, E.
A1  - Krichbaum, T. P.
A1  - Nestoras, I.
A1  - Fuhrmann, L.
A1  - Zensus, J. A.
A1  - Cassaro, P.
A1  - Orlati, A.
A1  - Maccaferri, G.
A1  - Leto, P.
A1  - Giroletti, M.
A1  - Richards, J. L.
A1  - Max-Moerbeck, W.
A1  - Readhead, A. C. S.
T1  - Multiband variability studies and novel broadband SED modeling of Mrk 501 in 2009
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Aims. We present an extensive study of the BL Lac object Mrk 501 based on a data set collected during the multi-instrument campaign spanning from 2009 March 15 to 2009 August 1, which includes, among other instruments, MAGIC, VERITAS, Whipple 10 m, and Fermi-LAT to cover the gamma-ray range from 0.1 GeV to 20 TeV; RXTE and Swift to cover wavelengths from UV to hard X-rays; and GASP-WEBT, which provides coverage of radio and optical wavelengths. Optical polarization measurements were provided for a fraction of the campaign by the Steward and St. Petersburg observatories. We evaluate the variability of the source and interband correlations, the gamma-ray flaring activity occurring in May 2009, and interpret the results within two synchrotron self-Compton (SSC) scenarios. Methods. The multiband variability observed during the full campaign is addressed in terms of the fractional variability, and the possible correlations are studied by calculating the discrete correlation function for each pair of energy bands where the significance was evaluated with dedicated Monte Carlo simulations. The space of SSC model parameters is probed following a dedicated grid-scan strategy, allowing for a wide range of models to be tested and offering a study of the degeneracy of model-to-data agreement in the individual model parameters, hence providing a less biased interpretation than the "single-curve SSC model adjustment" typically reported in the literature. Results. We find an increase in the fractional variability with energy, while no significant interband correlations of flux changes are found on the basis of the acquired data set. The SSC model grid-scan shows that the flaring activity around May 22 cannot be modeled adequately with a one-zone SSC scenario (using an electron energy distribution with two breaks), while it can be suitably described within a two (independent) zone SSC scenario. Here, one zone is responsible for the quiescent emission from the averaged 4.5-month observing period, while the other one, which is spatially separated from the first, dominates the flaring emission occurring at X-rays and very-high-energy (> 100 GeV, VHE) gamma-rays. The flaring activity from May 1, which coincides with a rotation of the electric vector polarization angle (EVPA), cannot be satisfactorily reproduced by either a one-zone or a two-independent-zone SSC model, yet this is partially affected by the lack of strictly simultaneous observations and the presence of large flux changes on sub-hour timescales (detected at VHE gamma rays). Conclusions. The higher variability in the VHE emission and lack of correlation with the X-ray emission indicate that, at least during the 4.5-month observing campaign in 2009, the highest energy (and most variable) electrons that are responsible for the VHE gamma rays do not make a dominant contribution to the similar to 1 keV emission. Alternatively, there could be a very variable component contributing to the VHE gamma-ray emission in addition to that coming from the SSC scenario. The studies with our dedicated SSC grid-scan show that there is some degeneracy in both the one-zone and the two-zone SSC scenarios probed, with several combinations of model parameters yielding a similar model-to-data agreement, and some parameters better constrained than others. The observed gamma-ray flaring activity, with the EVPA rotation coincident with the first gamma-ray flare, resembles those reported previously for low frequency peaked blazars, hence suggesting that there are many similarities in the flaring mechanisms of blazars with different jet properties.
KW  - BL Lacertae objects: individual: Markarian 501
KW  - methods: data analysis
Y1  - 2017
U6  - https://doi.org/10.1051/0004-6361/201629540
SN  - 1432-0746
VL  - 603
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Aichner, Bernhard
A1  - Hilt, Sabine
A1  - Perillon, Cecile
A1  - Gillefalk, Mikael
A1  - Sachse, Dirk
T1  - Biosynthetic hydrogen isotopic fractionation factors during lipid synthesis in submerged aquatic macrophytes: Effect of groundwater discharge and salinity
JF  - Organic geochemistry : the international journal for rapid publication of current research in organic geochemistry and biochemistry
N2  - Sedimentary lipid biomarkers have become widely used tools for reconstructing past climatic and ecological changes due to their ubiquitous occurrence in lake sediments. In particular, the hydrogen isotopic composition (expressed as delta D values) of leaf wax lipids derived from terrestrial plants has been a focus of research during the last two decades and the understanding of competing environmental and plant physiological factors influencing the delta D values has greatly improved. Comparatively less attention has been paid to lipid biomarkers derived from aquatic plants, although these compounds are abundant in many lacustrine sediments. We therefore conducted a field and laboratory experiment to study the effect of salinity and groundwater discharge on the isotopic composition of aquatic plant biomarkers. We analyzed samples of the common submerged plant species, Potamogeton pectinatus (sago pondweed), which has a wide geographic distribution and can tolerate high salinity. We tested the effect of groundwater discharge (characterized by more negative delta D values relative to lake water) and salinity on the delta D values of n-alkanes from P. pectinatus by comparing plants (i) collected from the oligotrophic freshwater Lake Stechlin (Germany) at shallow littoral depth from locations with and without groundwater discharge, and (ii) plants grown from tubers collected from the eutrophic Lake Muggelsee in nutrient solution at four salinity levels. Isotopically depleted groundwater did not have a significant influence on the delta D values of n-alkanes in Lake Stechlin P. pectinatus and calculated isotopic fractionation factors epsilon(l/w) between lake water and n-alkanes averaged -137 +/- 9%(n-C-23), -136 +/- 7%(n-C-25) and -131 +/- 6%(n-C-27), respectively. Similar epsilon values were calculated for plants from Lake Muggelsee grown in freshwater nutrient solution (-134 +/- 11% for n-C-23), while greater fractionation was observed at increased salinity values of 10 (163 +/- 12%) and 15(-172 +/- 15%). We therefore suggest an average e value of -136 +/- 9% between source water and the major n-alkanes in P. pectinatus grown under freshwater conditions. Our results demonstrate that isotopic fractionation can increase by 30-40% at salinity values 10 and 15. These results could be explained either by inhibited plant growth at higher salinity, or by metabolic adaptation to salt stress that remain to be elucidated. A potential salinity effect on dD values of aquatic lipids requires further examination, since this would impact on the interpretation of downcore isotopic data in paleohydrologic studies. (C) 2017 Elsevier Ltd. All rights reserved.
Y1  - 2017
U6  - https://doi.org/10.1016/j.orggeochem.2017.07.021
SN  - 0146-6380
VL  - 113
SP  - 10
EP  - 16
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Al-Ani, Ayad
T1  - CPS and the Worker
BT  - Reorientation and Requalification?
JF  - Industrial Internet of Things : Cybermanufacturing Systems
N2  - The idea of interlinked, sensor-augmented, self-governing Cyber Physical System (CPS) production processes is gaining momentum. At the same time, the impact of this concept on the workforce remains surprisingly vague. This can be explained by the fact that man is not at the centre of these developments and—even more importantly—automation is geared towards eliminating human activity. Based on the first views in the 1980s, the label of the “process worker” assumed an almost exclusive focus on control and maintenance tasks for this new type of worker in the automated factory. Recent experiences show, however, that as long as robots are not self-learning, man will be the template for these machines and we can already notice the emerging parallelism of fully automated production lines and human workshops. The changing nature of the workforce will gain further momentum if one depicts new, open formats of production. Here, the worker will have to assume new roles in reconfiguring the production processes.
Y1  - 2016
SN  - 978-3-319-42559-7
SN  - 978-3-319-42558-0
U6  - https://doi.org/10.1007/978-3-319-42559-7_23
SN  - 2365-4139
SP  - 563
EP  - 574
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Albert, Christian
A1  - Schroeter-Schlaack, Christoph
A1  - Hansjuergens, Bernd
A1  - Dehnhardt, Alexandra
A1  - Doering, Ralf
A1  - Job, Hubert
A1  - Koeppel, Johann
A1  - Kraetzig, Sebastian
A1  - Matzdorf, Bettina
A1  - Reutter, Michaela
A1  - Schaltegger, Stefan
A1  - Scholz, Mathias
A1  - Siegmund-Schultze, Marianna
A1  - Wiggering, Hubert
A1  - Woltering, Manuel
A1  - von Haaren, Christina
T1  - An economic perspective on land use decisions in agricultural landscapes: Insights from the TEEB Germany Study
JF  - Ecosystem Services : Science, Policy and Practice
N2  - Agricultural landscapes safeguard ecosystem services (ES) and biodiversity upon which human well-being depends. However, only a fraction of these services are generally considered in land management decisions, resulting in trade-offs and societally inefficient solutions. The TEEB Study (The Economics of Ecosystems and Biodiversity) spearheaded the development of assessments of the economic significance of ES and biodiversity. Several national TEEB follow-ups have compiled case studies and derived targeted policy advice. By synthesizing insights from "Natural Capital Germany - TEEB DE" and focusing on rural areas, the objectives of this study were (i) to explore causes of the continued decline of ES and biodiversity, (ii) to introduce case studies exemplifying the economic significance of ES and biodiversity in land use decisions, and (iii) to synthesize key recommendations for policy, planning and management. Our findings indicate that the continued decrease of ES and biodiversity in Germany can be explained by implementation deficits within a well-established nature conservation system. Three case studies on grassland protection, the establishment of riverbank buffer zones and water-sensitive farming illustrate that an economic perspective can convey recognition of the values of ES and biodiversity. We conclude with suggestions for enhanced consideration, improved conservation and sustainable use of ES and biodiversity. (C) 2017 Elsevier B.V. All rights reserved.
Y1  - 2017
U6  - https://doi.org/10.1016/j.ecoser.2017.03.020
SN  - 2212-0416
VL  - 25
SP  - 69
EP  - 78
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Algharably, Engi A. H.
A1  - Bolbrinker, Juliane
A1  - Lezius, Susanne
A1  - Reibis, Rona Katharina
A1  - Wegscheider, Karl
A1  - Völler, Heinz
A1  - Kreutz, Reinhold
T1  - Uromodulin associates with cardiorenal function in patients with hypertension and cardiovascular disease
JF  - Journal of hypertension
N2  - Objective:Common genetic variants in the gene encoding uromodulin (UMOD) have been associated with renal function, blood pressure (BP) and hypertension. We investigated the associations between an important single nucleotide polymorphism (SNP) in UMOD, that is rs12917707-G>T, and estimated glomerular filtration rate (eGFR), BP and cardiac organ damage as determined by echocardiography in patients with arterial hypertension.Methods:A cohort of 1218 treated high-risk patients (mean age 58.5 years, 83% men) with documented cardiovascular disease (81% with coronary heart disease) was analysed.Results:The mean values for 24-h SBP and DBP were 124.714.7 and 73.9 +/- 9.4mmHg; mean eGFR was 77.5 +/- 18.3ml/min per 1.73m(2), mean left ventricular ejection fraction was 59.3 +/- 9.9% and mean left ventricular mass index in men and women was 53.9 +/- 23.2 and 54.9 +/- 23.7g/m(2.7) with 50.4% of patients having left ventricular hypertrophy. A significant association between rs12917707 and eGFR was observed with T-allele carriers showing significantly higher eGFR values (+2.6ml/min per 1.73m(2), P=0.006) than noncarriers. This SNP associated also with left atrial diameter (P=0.007); homozygous carriers of the T-allele had smaller left atrial diameter (-1.5mm) than other genotype groups (P=0.040). No significant associations between rs12917707 and other cardiac or BP phenotypes were observed.Conclusions:These findings extend the previously documented role of UMOD for renal function also to treated high-risk patients with arterial hypertension and reveal a novel association with left atrial remodelling and thus a potential cardiorenal link modulated by UMOD.
KW  - blood pressure
KW  - cardiovascular complications
KW  - chronic kidney disease
KW  - genetics
KW  - hypertension
KW  - kidney function
KW  - organ damage
KW  - Tamm-Horsfall protein
Y1  - 2017
U6  - https://doi.org/10.1097/HJH.0000000000001432
SN  - 0263-6352
SN  - 1473-5598
VL  - 35
SP  - 2053
EP  - 2058
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Algieri, Bernardina
A1  - Kalkuhl, Matthias
A1  - Koch, Nicolas
T1  - A tale of two tails: Explaining extreme events in financialized agricultural markets
JF  - Food policy : economics planning and politics of food and agriculture
N2  - The substantial booms and busts in agricultural prices marked by extreme events across commodities lead to heated debates about the effects of speculative trading on commodity price fluctuations. This study proposes a new approach to understanding extreme events and boom-bust processes in agricultural markets. Using weekly futures data for twelve indexed agricultural commodities during 2006 to 2016, we find that extreme price changes, located in the 10% tails of the distribution, cluster across agricultural markets. We then implement a multinomial logit model to investigate which factors are associated with the propagation of extreme events. Specifically, we disentangle three transmission conduits. (1) The macroeconomic conduit captures the possibility that the synchronized extreme price events are generated by business-cycle driven demand shifts mainly in emerging economies. (2) The financial conduit refers to potential links between extreme returns and the increasing flow of money from financial participants into agricultural futures markets. (3) Finally, the energy conduit accounts for possible spillover effects due to oil price shocks. Our results indicate an important role of managed money positions and oil prices while the real demand channel remains mostly insignificant. (C) 2017 Elsevier Ltd. All rights reserved.
KW  - Agricultural prices
KW  - Futures market
KW  - Tail events
KW  - GARCH analysis
KW  - Multinomial logit
Y1  - 2017
U6  - https://doi.org/10.1016/j.foodpol.2017.05.004
SN  - 0306-9192
SN  - 1873-5657
VL  - 69
SP  - 256
EP  - 269
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Ali, Saleem H.
A1  - Giurco, Damien
A1  - Arndt, Nicholas
A1  - Nickless, Edmund
A1  - Brown, Graham
A1  - Demetriades, Alecos
A1  - Durrheim, Ray
A1  - Enriquez, Maria Amelia
A1  - Kinnaird, Judith
A1  - Littleboy, Anna
A1  - Meinert, Lawrence D.
A1  - Oberhänsli, Roland
A1  - Salem, Janet
A1  - Schodde, Richard
A1  - Schneider, Gabi
A1  - Vidal, Olivier
A1  - Yakovleva, Natalia
T1  - Mineral supply for sustainable development requires resource governance
JF  - Nature : the international weekly journal of science
N2  - Successful delivery of the United Nations sustainable development goals and implementation of the Paris Agreement requires technologies that utilize a wide range of minerals in vast quantities. Metal recycling and technological change will contribute to sustaining supply, but mining must continue and grow for the foreseeable future to ensure that such minerals remain available to industry. New links are needed between existing institutional frameworks to oversee responsible sourcing of minerals, trajectories for mineral exploration, environmental practices, and consumer awareness of the effects of consumption. Here we present, through analysis of a comprehensive set of data and demand forecasts, an interdisciplinary perspective on how best to ensure ecologically viable continuity of global mineral supply over the coming decades.
Y1  - 2017
U6  - https://doi.org/10.1038/nature21359
SN  - 0028-0836
SN  - 1476-4687
VL  - 543
SP  - 367
EP  - 372
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Alicke, Marie
A1  - Boakye-Appiah, Justice K.
A1  - Abdul-Jalil, Inusah
A1  - Henze, Andrea
A1  - van der Giet, Markus
A1  - Schulze, Matthias Bernd
A1  - Schweigert, Florian J.
A1  - Mockenhaupt, Frank P.
A1  - Bedu-Addo, George
A1  - Danquah, Ina
T1  - eAdolescent health in rural Ghana: A crosssectional study on the co-occurrence of infectious diseases, malnutrition and cardiometabolic risk factors
JF  - PLoS one
N2  - In sub-Saharan Africa, infectious diseases and malnutrition constitute the main health problems in children, while adolescents and adults are increasingly facing cardio-metabolic conditions. Among adolescents as the largest population group in this region, we investigated the co-occurrence of infectious diseases, malnutrition and cardio-metabolic risk factors (CRFs), and evaluated demographic, socio-economic and medical risk factors for these entities. In a cross-sectional study among 188 adolescents in rural Ghana, malarial infection, common infectious diseases and Body Mass Index were assessed. We measured ferritin, C-reactive protein, retinol, fasting glucose and blood pressure. Socio-demographic data were documented. We analyzed the proportions (95% confidence interval, CI) and the cooccurrence of infectious diseases (malaria, other common diseases), malnutrition (underweight, stunting, iron deficiency, vitamin A deficiency [VAD]), and CRFs (overweight, obesity, impaired fasting glucose, hypertension). In logistic regression, odds ratios (OR) and 95% CIs were calculated for the associations with socio-demographic factors. In this Ghanaian population (age range, 14.4-15.5 years; males, 50%), the proportions were for infectious diseases 45% (95% CI: 38-52%), for malnutrition 50% (43-57%) and for CRFs 16% (11- 21%). Infectious diseases and malnutrition frequently co-existed (28%; 21-34%). Specifically, VAD increased the odds of non-malarial infectious diseases 3-fold (95% CI: 1.03, 10.19). Overlap of CRFs with infectious diseases (6%; 2-9%) or with malnutrition (7%; 3-11%) was also present. Male gender and low socio-economic status increased the odds of infectious diseases and malnutrition, respectively. Malarial infection, chronic malnutrition and VAD remain the predominant health problems among these Ghanaian adolescents. Investigating the relationships with evolving CRFs is warranted.
Y1  - 2017
U6  - https://doi.org/10.1371/journal.pone.0180436
SN  - 1932-6203
VL  - 12
SP  - 4463
EP  - 4477
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Allen, C.
A1  - Archambault, S.
A1  - Archer, A.
A1  - Benbow, W.
A1  - Bird, R.
A1  - Bourbeau, E.
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Cardenzana, J. V.
A1  - Cerruti, M.
A1  - Chen, Xuhui
A1  - Christiansen, J. L.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Daniel, M. K.
A1  - Eisch, J. D.
A1  - Falcone, Abe
A1  - Feng, Q.
A1  - Fernandez-Alonso, M.
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Flinders, A.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Gillanders, G. H.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Huetten, M.
A1  - Hakansson, N.
A1  - Hanna, D.
A1  - Hervet, O.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kelley-Hoskins, N.
A1  - Kertzman, M.
A1  - Kieda, D.
A1  - Krause, M.
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Maier, G.
A1  - McArthur, S.
A1  - McCann, A.
A1  - Meagher, K.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nguyen, T.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Petrashyk, A.
A1  - Pichel, A.
A1  - Pohl, Martin
A1  - Popkow, A.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rovero, A. C.
A1  - Rulten, C.
A1  - Sadeh, I.
A1  - Santander, Marcos
A1  - Sembroski, G. H.
A1  - Shahinyan, K.
A1  - Telezhinsky, Igor O.
A1  - Tucci, J. V.
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
T1  - Very-High-Energy gamma-Ray Observations of the Blazar 1ES 2344+514 with VERITAS
JF  - Monthly notices of the Royal Astronomical Society
N2  - We present very-high-energy gamma-ray observations of the BL Lac object 1ES 2344+514 taken by the Very Energetic Radiation Imaging Telescope Array System between 2007 and 2015. 1ES 2344+514 is detected with a statistical significance above the background of 20.8 sigma in 47.2 h (livetime) of observations, making this the most comprehensive very-high-energy study of 1ES 2344+514 to date. Using these observations, the temporal properties of 1ES 2344+514 are studied on short and long times-scales. We fit a constant-flux model to nightly and seasonally binned light curves and apply a fractional variability test to determine the stability of the source on different time-scales. We reject the constant-flux model for the 2007-2008 and 2014-2015 nightly binned light curves and for the long-term seasonally binned light curve at the > 3 sigma level. The spectra of the time-averaged emission before and after correction for attenuation by the extragalactic background light are obtained. The observed time-averaged spectrum above 200 GeV is satisfactorily fitted (x(2)/NDF = 7.89/6) by a power-law function with an index Gamma = 2.46 +/- 0.06(stat) +/- 0.20(sys) and extends to at least 8 TeV. The extragalactic-backgroundlight-deabsorbed spectrum is adequately fit (x(2)/NDF = 6.73/6) by a power-law function with an index Gamma = 2.15 +/- 0.06(stat) +/- 0.20(sys) while an F-test indicates that the power law with an exponential cut-off function provides a marginally better fit (x(2)/NDF = 2.56/5) at the 2.1 sigma level. The source location is found to be consistent with the published radio location and its spatial extent is consistent with a point source.
KW  - astroparticle physics
KW  - BL Lacertae objects: individual: 1ES 2344+514=VERJ2347+517
KW  - gamma-rays: galaxies
Y1  - 2017
U6  - https://doi.org/10.1093/mnras/stx1756
SN  - 0035-8711
SN  - 1365-2966
VL  - 471
SP  - 2117
EP  - 2123
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Allu, Annapurna Devi
A1  - Simancas, Barbara
A1  - Balazadeh, Salma
A1  - Munne-Bosch, Sergi
T1  - Defense-Related Transcriptional Reprogramming in Vitamin E-Deficient Arabidopsis Mutants Exposed to Contrasting Phosphate Availability
JF  - Frontiers in plant science
N2  - Vitamin E inhibits the propagation of lipid peroxidation and helps protecting photosystem II from photoinhibition, but little is known about its possible role in plant response to Pi availability. Here, we aimed at examining the effect of vitamin E deficiency in Arabidopsis thaliana vte mutants on phytohormone contents and the expression of transcription factors in plants exposed to contrasting Pi availability. Plants were subjected to two doses of Pi, either unprimed (controls) or previously exposed to low Pi (primed). In the wild type, alpha-tocopherol contents increased significantly in response to repeated periods of low Pi, which was paralleled by increased growth, indicative of a priming effect. This growth-stimulating effect was, however, abolished in vte mutants. Hormonal profiling revealed significant effects of Pi availability, priming and genotype on the contents of jasmonates and salicylates; remarkably, vte mutants showed enhanced accumulation of both hormones under low Pi. Furthermore, expression profiling of 1,880 transcription factors by qRT-PCR revealed a pronounced effect of priming on the transcript levels of 45 transcription factors mainly associated with growth and stress in wild-type plants in response to low Pi availability; while distinct differences in the transcriptional response were detected in vte mutants. We conclude that alpha-tocopherol plays a major role in the response of plants to Pi availability not only by protecting plants from photo-oxidative stress, but also by exerting a control over growth-and defense-related transcriptional reprogramming and hormonal modulation.
KW  - antioxidants
KW  - photosystem II
KW  - plastochromanol-8
KW  - priming
KW  - retrograde signaling
KW  - tocochromanols
KW  - vitamin E
Y1  - 2017
U6  - https://doi.org/10.3389/fpls.2017.01396
SN  - 1664-462X
VL  - 8
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Almeida, Leonardo A.
A1  - Sana, H.
A1  - Taylor, W.
A1  - Barbá, Rodolfo
A1  - Bonanos, Alceste Z.
A1  - Crowther, Paul
A1  - Damineli, Augusto
A1  - de Koter, A.
A1  - de Mink, Selma E.
A1  - Evans, C. J.
A1  - Gieles, Mark
A1  - Grin, Nathan J.
A1  - Hénault-Brunet, V.
A1  - Langer, Norbert
A1  - Lennon, D.
A1  - Lockwood, Sean
A1  - Maíz Apellániz, Jesús
A1  - Moffat, A. F. J.
A1  - Neijssel, C.
A1  - Norman, C.
A1  - Ramírez-Agudelo, O. H.
A1  - Richardson, N. D.
A1  - Schootemeijer, Abel
A1  - Shenar, Tomer
A1  - Soszyński, Igor
A1  - Tramper, Frank
A1  - Vink, J. S.
T1  - The tarantula massive binary monitoring
BT  - I. Observational campaign and OB-type spectroscopic binaries
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Context:
Massive binaries play a crucial role in the Universe. Knowing the distributions of their orbital parameters is important for a wide range of topics from stellar feedback to binary evolution channels and from the distribution of supernova types to gravitational wave progenitors, yet no direct measurements exist outside the Milky Way.
Aims:
The Tarantula Massive Binary Monitoring project was designed to help fill this gap by obtaining multi-epoch radial velocity (RV) monitoring of 102 massive binaries in the 30 Doradus region.
Methods: 
In this paper we analyze 32 FLAMES/GIRAFFE observations of 93 O- and 7 B-type binaries. We performed a Fourier analysis and obtained orbital solutions for 82 systems: 51 single-lined (SB1) and 31 double-lined (SB2) spectroscopic binaries.
Results: 
Overall, the binary fraction and orbital properties across the 30 Doradus region are found to be similar to existing Galactic samples. This indicates that within these domains environmental effects are of second order in shaping the properties of massive binary systems. A small difference is found in the distribution of orbital periods, which is slightly flatter (in log space) in 30 Doradus than in the Galaxy, although this may be compatible within error estimates and differences in the fitting methodology. Also, orbital periods in 30 Doradus can be as short as 1.1 d, somewhat shorter than seen in Galactic samples. Equal mass binaries (q> 0.95) in 30 Doradus are all found outside NGC 2070, the central association that surrounds R136a, the very young and massive cluster at 30 Doradus’s core. Most of the differences, albeit small, are compatible with expectations from binary evolution. One outstanding exception, however, is the fact that earlier spectral types (O2–O7) tend to have shorter orbital periods than later spectral types (O9.2–O9.7).
Conclusions: 
Our results point to a relative universality of the incidence rate of massive binaries and their orbital properties in the metallicity range from solar (Z⊙) to about half solar. This provides the first direct constraints on massive binary properties in massive star-forming galaxies at the Universe’s peak of star formation at redshifts z ~ 1 to 2 which are estimated to have Z ~ 0.5 Z⊙.
KW  - stars: early-type
KW  - stars: massive
KW  - binaries: spectroscopic
KW  - binaries: close
Y1  - 2017
U6  - https://doi.org/10.1051/0004-6361/201629844
SN  - 1432-0746
VL  - 598
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Alsaedy, Ammar
A1  - Tarkhanov, Nikolai Nikolaevich
T1  - A Hilbert Boundary Value Problem for Generalised Cauchy-Riemann Equations
JF  - Advances in applied Clifford algebras
N2  - We elaborate a boundary Fourier method for studying an analogue of the Hilbert problem for analytic functions within the framework of generalised Cauchy-Riemann equations. The boundary value problem need not satisfy the Shapiro-Lopatinskij condition and so it fails to be Fredholm in Sobolev spaces. We show a solvability condition of the Hilbert problem, which looks like those for ill-posed problems, and construct an explicit formula for approximate solutions.
KW  - Dirac operator
KW  - Clifford algebra
KW  - Riemann-Hilbert problem
KW  - Fredholm operators
Y1  - 2017
U6  - https://doi.org/10.1007/s00006-016-0676-8
SN  - 0188-7009
SN  - 1661-4909
VL  - 27
SP  - 931
EP  - 953
PB  - Springer
CY  - Basel
ER  - 
TY  - JOUR
A1  - Amalfitano, Stefano
A1  - Corno, Gianluca
A1  - Eckert, Ester
A1  - Fazi, Stefano
A1  - Ninio, Shira
A1  - Callieri, Cristiana
A1  - Grossart, Hans-Peter
A1  - Eckert, Werner
T1  - Tracing particulate matter and associated microorganisms in freshwaters
JF  - Hydrobiologia : acta hydrobiologica, hydrographica, limnologica et protistologica
N2  - Sediment resuspension represents a key process in all natural aquatic systems, owing to its role in nutrient cycling and transport of potential contaminants. Although suspended solids are generally accepted as an important quality parameter, current monitoring programs cover quantitative aspects only. Established methodologies do not provide information on origin, fate, and risks associated with uncontrolled inputs of solids in waters. Here we discuss the analytical approaches to assess the occurrence and ecological relevance of resuspended particulate matter in freshwaters, with a focus on the dynamics of associated contaminants and microorganisms. Triggered by the identification of specific physical-chemical traits and community structure of particle-associated microorganisms, recent findings suggest that a quantitative determination of microorganisms can be reasonably used to trace the origin of particulate matter by means of nucleic acid-based assays in different aquatic systems.
KW  - Total suspended solids
KW  - Resuspended particulate
KW  - Turbidity
KW  - Sediment traps
KW  - Particle-associated microorganisms
KW  - Pathogens
Y1  - 2017
U6  - https://doi.org/10.1007/s10750-017-3260-x
SN  - 0018-8158
SN  - 1573-5117
VL  - 800
SP  - 145
EP  - 154
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Aminov, Jovid
A1  - Ding, Lin
A1  - Mamadjonov, Yunus
A1  - Dupont-Nivet, Guillaume
A1  - Aminov, Jamshed
A1  - Zhang, Li-Yun
A1  - Yoqubov, Shokirjon
A1  - Aminov, Javhar
A1  - Abdulov, Sherzod
T1  - Pamir Plateau formation and crustal thickening before the India-Asia collision inferred from dating and petrology of the 110-92 Ma Southern Pamir volcanic sequence
JF  - Gondwana research : international geoscience journal ; official journal of the International Association for Gondwana Research
N2  - The formation of the Pamir is a key component of the India-Asia collision with major implications for lithospheric processes, plateau formation, land-sea configurations and associated climate changes. Although the formation of the Pamir is traditionally linked to Cenozoic processes associated with the India-Asia collision, the contribution of the Mesozoic tectonic evolution remains poorly understood. The Pamir was formed by the suturing of Gondwanan terranes to the south margin of Eurasia, however, the timing and tectonic mechanisms associated with this Mesozoic accretion remain poorly constrained. These processes are recorded by several igneous belts within these terranes, which are not well studied. Within the Southern Pamir, the Albian-Turonian volcanic rocks and comagmatic plutons of the Kyzylrabat Igneous Complex (KIC) provide an important and still unconstrained record of the Pamir evolution. Here we provide the age, origin and the geodynamic setting of the KIC volcanics by studying their petrology, zircon U-Pb geochronology, geochemistry and isotope composition.17 samples from the KIC volcanics yield U-Pb ages spanning from 92 to 110 Ma. The volcanics are intermediate to acidic in composition (SiO2 = 56-69 wt%) and exhibit high-K calc-alkaline and shoshonitic affinity (K2O/Na2O = 12.2 wt%). They show enrichment in LILE and LREE and depletion in HFSE and HREE with negative Ta, Ti and Nb anomalies, suggesting an arc-related tectonic setting for their formation. Low sNd(t) values (from 9.1 to 4.7), relatively high Sr-87/Sr-86(i) ratios (0.7069-0.7096) and broad range of zircon stif values (from 22.6 to 1.5) suggest a mixture of different magma sources. These features suggest that volcanics were derived by crustal under- or intraplating of an enriched subduction-related mantle shoshonitic magmas, by heating and partial melting of the lower crust, and by mixing of both magma components. Our results further imply that the KIC volcanics represent a shoshonitic suite typical of an evolution from active continental arc to post-collisional setting with a steepening of the Benioff zone and thickening of the crust toward the back-arc. This setting is best explained by the subduction- collision transition along the Shyok suture due to accretion of the Kohistan island arc to the Karakoram. This suggests that a significant part of the crustal shortening and thickening accommodated in the Pamir occurred in the Mesozoic before the India-Asia collision with implications for regional tectonic models. This further suggests the Pamir was already a major topographic feature with potentially important paleoclimate forcing such as the monsoonal circulation. (C) 2017 International Association for Gondwana Research. Published by Elsevier B.V. All rights reserved.
KW  - Southern Pamir
KW  - Cretaceous
KW  - Volcanic rocks
KW  - Geochemistry
KW  - Geochronology
KW  - Petrogenesis
Y1  - 2017
U6  - https://doi.org/10.1016/j.gr.2017.08.003
SN  - 1342-937X
SN  - 1878-0571
VL  - 51
SP  - 310
EP  - 326
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Anderson, Craig A.
A1  - Suzuki, Kanae
A1  - Swing, Edward L.
A1  - Groves, Christopher L.
A1  - Gentile, Douglas A.
A1  - Prot, Sara
A1  - Lam, Chun Pan
A1  - Sakamoto, Akira
A1  - Horiuchi, Yukiko
A1  - Krahé, Barbara
A1  - Jelic, Margareta
A1  - Wei Liuqing, 
A1  - Toma, Roxana
A1  - Warburton, Wayne A.
A1  - Zhang, Xue-Min
A1  - Tajima, Sachi
A1  - Qing, Feng
A1  - Petrescu, Poesis
T1  - Media Violence and Other Aggression Risk Factors in Seven Nations
JF  - Personality and social psychology bulletin
N2  - Cultural generality versus specificity of media violence effects on aggression was examined in seven countries (Australia, China, Croatia, Germany, Japan, Romania, the United States). Participants reported aggressive behaviors, media use habits, and several other known risk and protective factors for aggression. Across nations, exposure to violent screen media was positively associated with aggression. This effect was partially mediated by aggressive cognitions and empathy. The media violence effect on aggression remained significant even after statistically controlling a number of relevant risk and protective factors (e.g., abusive parenting, peer delinquency), and was similar in magnitude to effects of other risk factors. In support of the cumulative risk model, joint effects of different risk factors on aggressive behavior in each culture were larger than effects of any individual risk factor.
KW  - mass media
KW  - aggression
KW  - culture
KW  - ethnicity
Y1  - 2017
U6  - https://doi.org/10.1177/0146167217703064
SN  - 0146-1672
SN  - 1552-7433
VL  - 43
SP  - 986
EP  - 998
PB  - Sage Publ.
CY  - Thousand Oaks
ER  - 
TY  - JOUR
A1  - Andrews, N. L. P.
A1  - Ferguson, T.
A1  - Rangaswamy, A. M. M.
A1  - Bernicky, A. R.
A1  - Henning, N.
A1  - Dudelzak, A.
A1  - Reich, Oliver
A1  - Barnes, Jack A.
A1  - Loock, Hans-Peter
T1  - Hadamard-Transform Fluorescence Excitation-Emission-Matrix Spectroscopy
JF  - Analytical chemistry
N2  - We present a fluorescence excitation-emission-matrix spectrometer with superior data acquisition rates over previous instruments. Light from a white light emitting diode (LED) source is dispersed onto a digital micromirror array (DMA) and encoded using binary n-size Walsh functions ("barcodes"). The encoded excitation light is used to irradiate the liquid sample and its fluorescence is dispersed and detected using a conventional array spectrometer. After exposure to excitation light encoded in n different ways, the 2-dimensional excitation-emission-matrix (EEM) spectrum is obtained by inverse Hadamard transformation. Using this technique we examined the kinetics of the fluorescence of rhodamine B as a function of temperature and the acid-driven demetalation of chlorophyll into pheophytin-a. For these experiments, EEM spectra with 31 excitation channels and 2048 emission channels were recorded every 15 s. In total, data from over 3000 EEM spectra were included in this report. It is shown that the increase in data acquisition rate can be as high as [{n(n + 1)}/2]-fold over conventional EEM spectrometers. Spectral acquisition rates of more than two spectra per second were demonstrated.
Y1  - 2017
U6  - https://doi.org/10.1021/acs.analchem.7b02400
SN  - 0003-2700
SN  - 1520-6882
VL  - 89
SP  - 8554
EP  - 8564
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Angermann, Lisa
A1  - Jackisch, Conrad
A1  - Allroggen, Niklas
A1  - Sprenger, Matthias
A1  - Zehe, Erwin
A1  - Tronicke, Jens
A1  - Weiler, Markus
A1  - Blume, Theresa
T1  - Form and function in hillslope hydrology: characterization of subsurface flow based on response observations
JF  - Hydrology and earth system sciences : HESS
N2  - The phrase form and function was established in architecture and biology and refers to the idea that form and functionality are closely correlated, influence each other, and co-evolve. We suggest transferring this idea to hydrological systems to separate and analyze their two main characteristics: their form, which is equivalent to the spatial structure and static properties, and their function, equivalent to internal responses and hydrological behavior. While this approach is not particularly new to hydrological field research, we want to employ this concept to explicitly pursue the question of what information is most advantageous to understand a hydrological system. We applied this concept to subsurface flow within a hillslope, with a methodological focus on function: we conducted observations during a natural storm event and followed this with a hillslope-scale irrigation experiment. The results are used to infer hydrological processes of the monitored system. Based on these findings, the explanatory power and conclusiveness of the data are discussed. The measurements included basic hydrological monitoring methods, like piezometers, soil moisture, and discharge measurements. These were accompanied by isotope sampling and a novel application of 2-D time-lapse GPR (ground-penetrating radar). The main finding regarding the processes in the hillslope was that preferential flow paths were established quickly, despite unsaturated conditions. These flow paths also caused a detectable signal in the catchment response following a natural rainfall event, showing that these processes are relevant also at the catchment scale. Thus, we conclude that response observations (dynamics and patterns, i.e., indicators of function) were well suited to describing processes at the observational scale. Especially the use of 2-D time-lapse GPR measurements, providing detailed subsurface response patterns, as well as the combination of stream-centered and hillslope-centered approaches, allowed us to link processes and put them in a larger context. Transfer to other scales beyond observational scale and generalizations, however, rely on the knowledge of structures (form) and remain speculative. The complementary approach with a methodological focus on form (i.e., structure exploration) is presented and discussed in the companion paper by Jackisch et al. (2017).
Y1  - 2017
U6  - https://doi.org/10.5194/hess-21-3727-2017
SN  - 1027-5606
SN  - 1607-7938
VL  - 21
SP  - 3727
EP  - 3748
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Anielski, Alexander
A1  - Barbosa Pfannes, Eva Katharina
A1  - Beta, Carsten
T1  - Adaptive microfluidic gradient generator for quantitative chemotaxis experiments
JF  - Review of scientific instruments : a monthly journal devoted to scientific instruments, apparatus, and techniques
N2  - Chemotactic motion in a chemical gradient is an essential cellular function that controls many processes in the living world. For a better understanding and more detailed modelling of the underlying mechanisms of chemotaxis, quantitative investigations in controlled environments are needed. We developed a setup that allows us to separately address the dependencies of the chemotactic motion on the average background concentration and on the gradient steepness of the chemoattractant. In particular, both the background concentration and the gradient steepness can be kept constant at the position of the cell while it moves along in the gradient direction. This is achieved by generating a well-defined chemoattractant gradient using flow photolysis. In this approach, the chemoattractant is released by a light-induced reaction from a caged precursor in a microfluidic flow chamber upstream of the cell. The flow photolysis approach is combined with an automated real-time cell tracker that determines changes in the cell position and triggers movement of the microscope stage such that the cell motion is compensated and the cell remains at the same position in the gradient profile. The gradient profile can be either determined experimentally using a caged fluorescent dye or may be alternatively determined by numerical solutions of the corresponding physical model. To demonstrate the function of this adaptive microfluidic gradient generator, we compare the chemotactic motion of Dictyostelium discoideum cells in a static gradient and in a gradient that adapts to the position of the moving cell. Published by AIP Publishing.
Y1  - 2017
U6  - https://doi.org/10.1063/1.4978535
SN  - 0034-6748
SN  - 1089-7623
VL  - 88
PB  - American Institute of Physics
CY  - Melville
ER  - 
TY  - JOUR
A1  - Annunziata, Maria Grazia
A1  - Apelt, Federico
A1  - Carillo, Petronia
A1  - Krause, Ursula
A1  - Feil, Regina
A1  - Mengin, Virginie
A1  - Lauxmann, Martin A.
A1  - Koehl, Karin
A1  - Nikoloski, Zoran
A1  - Stitt, Mark
A1  - Lunn, John Edward
T1  - Getting back to nature: a reality check for experiments in controlled environments
JF  - Journal of experimental botany
N2  - Irradiance from sunlight changes in a sinusoidal manner during the day, with irregular fluctuations due to clouds, and light-dark shifts at dawn and dusk are gradual. Experiments in controlled environments typically expose plants to constant irradiance during the day and abrupt light-dark transitions. To compare the effects on metabolism of sunlight versus artificial light regimes, Arabidopsis thaliana plants were grown in a naturally illuminated greenhouse around the vernal equinox, and in controlled environment chambers with a 12-h photoperiod and either constant or sinusoidal light profiles, using either white fluorescent tubes or light-emitting diodes (LEDs) tuned to a sunlight-like spectrum as the light source. Rosettes were sampled throughout a 24-h diurnal cycle for metabolite analysis. The diurnal metabolite profiles revealed that carbon and nitrogen metabolism differed significantly between sunlight and artificial light conditions. The variability of sunlight within and between days could be a factor underlying these differences. Pairwise comparisons of the artificial light sources (fluorescent versus LED) or the light profiles (constant versus sinusoidal) showed much smaller differences. The data indicate that energy-efficient LED lighting is an acceptable alternative to fluorescent lights, but results obtained from plants grown with either type of artificial lighting might not be representative of natural conditions.
KW  - Amino acid
KW  - Arabidopsis thaliana
KW  - controlled environment
KW  - LED lighting
KW  - visible light spectrum
KW  - organic acid
KW  - starch
KW  - sucrose
KW  - trehalose 6-phosphate
Y1  - 2017
U6  - https://doi.org/10.1093/jxb/erx220
SN  - 0022-0957
SN  - 1460-2431
VL  - 68
SP  - 4463
EP  - 4477
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Apelt, Federico
A1  - Breuer, David
A1  - Olas, Justyna Jadwiga
A1  - Annunziata, Maria Grazia
A1  - Flis, Anna
A1  - Nikoloski, Zoran
A1  - Kragler, Friedrich
A1  - Stitt, Mark
T1  - Circadian, Carbon, and Light Control of Expansion Growth and Leaf Movement
JF  - Plant physiology : an international journal devoted to physiology, biochemistry, cellular and molecular biology, biophysics and environmental biology of plants
Y1  - 2017
U6  - https://doi.org/10.1104/pp.17.00503
SN  - 0032-0889
SN  - 1532-2548
VL  - 174
SP  - 1949
EP  - 1968
PB  - American Society of Plant Physiologists
CY  - Rockville
ER  - 
TY  - JOUR
A1  - Apelt, Maja
A1  - Besio, Cristina
A1  - Corsi, Giancarlo
A1  - von Groddeck, Victoria
A1  - Grothe-Hammer, Michael
A1  - Tacke, Veronika
T1  - Resurrecting organization without renouncing society
BT  - a response to Ahrne, Brunsson and Seidl
JF  - European management journal
N2  - In a recent article in this journal, Ahrne, Brunsson, and Seidl (2016) suggest a definition of organization as a ‘decided social order’ composed of five elements (membership, rules, hierarchies, monitoring, and sanctions) which rest on decisions. ‘Partial organization’ uses only one or a few of these decidable elements while ‘complete organization’ uses them all. Such decided orders may also occur outside formal organizations, as the authors observe. Although we appreciate the idea of improving our understanding of organization(s) in modern society, we believe that Ahrne, Brunsson, and Seidl's suggestion jeopardizes the concept of organization by blurring its specific meaning. As the authors already draw on the work of Niklas Luhmann, we propose taking this exploration a step further and the potential of systems theory more seriously. Organizational analysis would then be able to retain a distinctive notion of formal organization on the one hand while benefiting from an encompassing theory of modern society on the other. With this extended conceptual framework, we would expect to gain a deeper understanding of how organizations implement and shape different societal realms as well as mediate between their particular logics, and, not least, how they are related to non-organizational social forms (e.g. families).
KW  - Partial organization
KW  - Formal organization
KW  - Organization theory
KW  - Niklas
KW  - Luhmann
KW  - Functional differentiation
KW  - Organizations and society
Y1  - 2017
U6  - https://doi.org/10.1016/j.emj.2017.01.002
SN  - 0263-2373
SN  - 1873-5681
VL  - 35
IS  - 1
SP  - 8
EP  - 14
PB  - Elsevier Science
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Aramayo, Alejandro
A1  - Guzman, Silvina
A1  - Hongn, Fernando D.
A1  - del Papa, Cecilia
A1  - Montero-Lopez, Carolina
A1  - Sudo, Masafumi
T1  - A Middle Miocene (13.5-12 Ma) deformational event constrained by volcanism along the Puna-Eastern Cordillera border, NW Argentina
JF  - Tectonophysics : international journal of geotectonics and the geology and physics of the interior of the earth
N2  - The features of Middle Miocene deposits in the Puna-Eastern Cordillera transition (Valles Calchaquies) indicate that Cenozoic deformation, sedimentation and volcanism follow a complex spatiotemporal relationship. The intense volcanic activity recorded in the eastern Puna border between 14 and 11.5 Ma coincides with the occurrence of one of the most important deformation events of the Neogene tectonic evolution in the region. Studies performed across the Puna-Eastern Cordillera transition show different relationships between volcanic deposits of ca. 13.5-12.1 Ma and the Oligocene-Miocene Angastaco Formation. In this paper we describe the ash-flow tuff deposits which are the first of this type found concordant in the sedimentary fill of Valles Calchaquies. Several analyses performed on these pyroclastic deposits allow a correlation to be made with the Alto de Las Lagunas Ignimbrite (ca. 13.5 Ma) of the Pucarilla-Cerro Tipillas Volcanic Complex located in the Puna. Outcrops of the ca. 13.5 Ma pyroclastic deposits are recognised within the Puna and the Valle Calchaqui. However, in the southern prolongation of the Valle de Hualfin (Tiopampa-Pucarilla depression) that separates the Puna from the Valle Calchaqui at these latitudes, these deposits are partially eroded and buried, and thus their occurrence is recorded only by abundant volcanic clasts included in conglomerates of the Angastaco Formation. The sedimentation of the Angastaco Formation was aborted at ca. 12 Ma in the Tiopampa-Pucarilla depression by the Pucarilla Ignimbrite, which unconformably covers the synorogenic units. On the contrary, in the Valle Calchaqui the sedimentation of the Angastaco Formation continued until the Late Miocene. The different relationships between the Miocene Angastaco Formation and the ignimbrites with ages of ca. 13.5 and ca. 12 Ma reveal that in this short period (-1.5 m.y.) a significant deformation event took place and resulted in marked palaeogeographic changes, as evidenced by stratigraphic-sedimentological and chronological records in the Angastaco Formation. (C) 2017 Elsevier B.V. All rights reserved.
KW  - Angastaco Formation
KW  - Miocene deformation
KW  - Alto de Las Lagunas Ignimbrite
KW  - Luingo caldera
KW  - Foreland
Y1  - 2017
U6  - https://doi.org/10.1016/j.tecto.2017.02.018
SN  - 0040-1951
SN  - 1879-3266
VL  - 703
SP  - 9
EP  - 22
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Arantzeta, Miren
A1  - Bastiaanse, Roelien
A1  - Burchert, Frank
A1  - Wieling, Martijn Benjamin
A1  - Martinez-Zabaleta, Maite
A1  - Laka, Itziar
T1  - Eye-tracking the effect of word order in sentence comprehension in aphasia
BT  - evidence from Basque, a free word order ergative language
JF  - Language, cognition and neuroscience
N2  - Agrammatic speakers of languages with overt grammatical case show impaired use of the morphological cues to establish theta-role relations in sentences presented in non-canonical word orders. We analysed the effect of word order on the sentence comprehension of aphasic speakers of Basque, an ergative, free word order and head-final (SOV) language. Ergative languages such as Basque establish a one-to-one mapping of the thematic role and the case marker. We collected behavioural and gaze-fixation data while agrammatic speakers performed a picture-matching task with auditorily presented sentences with different word orders. We found that people with aphasia (PWA) had difficulties in assigning theta-roles in Theme-Agent order. This result is in line with processing accounts. Contrary to previous findings, our data do not suggest a systematic delay in the integration of morphological information in the PWA group, but strong reliance on the ergative case morphology and difficulties assigning thematic roles into the determiner phrases.
KW  - Aphasia
KW  - comprehension
KW  - Basque
KW  - sentence processing
KW  - eye-tracking
Y1  - 2017
U6  - https://doi.org/10.1080/23273798.2017.1344715
SN  - 2327-3798
SN  - 2327-3801
VL  - 32
IS  - 10
SP  - 1320
EP  - 1343
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Archambault, S.
A1  - Archer, A.
A1  - Benbow, W.
A1  - Bird, R.
A1  - Bourbeau, E.
A1  - Brantseg, T.
A1  - Buchovecky, M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Byrum, K.
A1  - Cerruti, M.
A1  - Christiansen, J. L.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Daniel, M. K.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Geringer-Sameth, A.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Hütten, M.
A1  - Hakansson, N.
A1  - Hanna, D.
A1  - Hervet, O.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Hummensky, B.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kelley-Hoskins, N.
A1  - Kertzman, M.
A1  - Kieda, D.
A1  - Koushiappas, S.
A1  - Krause, M.
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Pohl, M.
A1  - Popkow, A.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rulten, C.
A1  - Sadeh, I.
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Shahinyan, K.
A1  - Smith, A. W.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Trepanier, S.
A1  - Tucci, J. V.
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Wilcox, P.
A1  - Williams, D. A.
A1  - Zitzer, B.
T1  - Dark matter constraints from a joint analysis of dwarf Spheroidal galaxy observations with VERITAS
JF  - Physical review : D, Particles, fields, gravitation, and cosmology
N2  - We present constraints on the annihilation cross section of weakly interacting massive particles dark matter based on the joint statistical analysis of four dwarf galaxies with VERITAS. These results are derived from an optimized photon weighting statistical technique that improves on standard imaging atmospheric Cherenkov telescope (IACT) analyses by utilizing the spectral and spatial properties of individual photon events. We report on the results of similar to 230 hours of observations of five dwarf galaxies and the joint statistical analysis of four of the dwarf galaxies. We find no evidence of gamma-ray emission from any individual dwarf nor in the joint analysis. The derived upper limit on the dark matter annihilation cross section from the joint analysis is 1.35 x 10(-23) cm(3) s(-1) at 1 TeV for the bottom quark (b (b) over bar) final state, 2.85 x 10(-24) cm(3) s(-1) at 1 TeV for the tau lepton (tau+tau(-)) final state and 1.32 x 10-25 cm(3) s(-1) at 1 TeV for the gauge boson (gamma gamma) final state.
Y1  - 2017
U6  - https://doi.org/10.1103/PhysRevD.95.082001
SN  - 2470-0010
SN  - 2470-0029
VL  - 95
IS  - 8
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - JOUR
A1  - Archambault, S.
A1  - Archer, A.
A1  - Benbow, W.
A1  - Bird, Ralph
A1  - Bourbeau, E.
A1  - Bouvier, A.
A1  - Buchovecky, M.
A1  - Bugaev, V.
A1  - Cardenzana, J. V.
A1  - Cerruti, M.
A1  - Ciupik, L.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Daniel, M. K.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Gillanders, G. H.
A1  - Griffin, S.
A1  - Hanna, D.
A1  - Hervet, O.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Hutten, M.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kertzman, M.
A1  - Kieda, D.
A1  - Krause, M.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - Maier, G.
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Pohl, Martin
A1  - Popkow, A.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rulten, C.
A1  - Sadeh, I.
A1  - Sembroski, G. H.
A1  - Shahinyan, K.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Trepanier, S.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Wilcox, P.
A1  - Williams, D. A.
A1  - Zitzer, B.
T1  - Gamma-ray observations under bright moonlight with VERITAS
JF  - Astroparticle physics
N2  - Imaging atmospheric Cherenkov telescopes (IACTs) are equipped with sensitive photomultiplier tube (PMT) cameras. Exposure to high levels of background illumination degrades the efficiency of and potentially destroys these photo-detectors over time, so IACTs cannot be operated in the same configuration in the presence of bright moonlight as under dark skies. Since September 2012, observations have been carried out with the VERITAS IACTs under bright moonlight (defined as about three times the night-sky-background (NSB) of a dark extragalactic field, typically occurring when Moon illumination > 35%) in two observing modes, firstly by reducing the voltage applied to the PMTs and, secondly, with the addition of ultra-violet (UV) bandpass filters to the cameras. This has allowed observations at up to about 30 times previous NSB levels (around 80% Moon illumination), resulting in 30% more observing time between the two modes over the course of a year. These additional observations have already allowed for the detection of a flare from the 1ES 1727 + 502 and for an observing program targeting a measurement of the cosmic-ray positron fraction. We provide details of these new observing modes and their performance relative to the standard VERITAS observations. (C) 2017 Elsevier B.V. All rights reserved.
KW  - Instrumentation
KW  - Moonlight
KW  - Observing methods
KW  - VERITAS
KW  - IACT
Y1  - 2017
U6  - https://doi.org/10.1016/j.astropartphys.2017.03.001
SN  - 0927-6505
SN  - 1873-2852
VL  - 91
SP  - 34
EP  - 43
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Archambault, S.
A1  - Archer, A.
A1  - Benbow, W.
A1  - Buchovecky, M.
A1  - Bugaev, V.
A1  - Cerruti, M.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Falcone, A.
A1  - Alonso, M. Fernandez
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Griffin, S.
A1  - Hutten, M.
A1  - Hervet, O.
A1  - Holder, J.
A1  - Humensky, T. B.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kieda, D.
A1  - Krause, M.
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - Maier, G.
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Pohl, M.
A1  - Popkow, A.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rovero, A. C.
A1  - Sadeh, I.
A1  - Shahinyan, K.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Weisgarber, T.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Zitzer, B.
T1  - Search for Magnetically Broadened Cascade Emission from Blazars with VERITAS
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We present a search for magnetically broadened gamma-ray emission around active galactic nuclei (AGNs), using VERITAS observations of seven hard-spectrum blazars. A cascade process occurs when multi-TeV gamma-rays from an AGN interact with extragalactic background light (EBL) photons to produce electron-positron pairs, which then interact with cosmic microwave background photons via inverse-Compton scattering to produce gamma-rays. Due to the deflection of the electron- positron pairs, a non-zero intergalactic magnetic field (IGMF) would potentially produce detectable effects on the angular distribution of the cascade emission. In particular, an angular broadening compared to the unscattered emission could occur. Through non-detection of angularly broadened emission from 1ES 1218 vertical bar 304, the source with the largest predicted cascade fraction, we exclude a range of IGMF strengths around 10(-14) G at the 95% confidence level. The extent of the exclusion range varies with the assumptions made about the intrinsic spectrum of 1ES. 1218+304 and the EBL model used in the simulation of the cascade process. All of the sources are used to set limits on the flux due to extended emission.
KW  - BL Lacertae objects: general
KW  - galaxies: active
KW  - gamma rays: galaxies
KW  - magnetic fields
Y1  - 2017
U6  - https://doi.org/10.3847/1538-4357/835/2/288
SN  - 0004-637X
SN  - 1538-4357
VL  - 835
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Archambault, S.
A1  - Archer, A.
A1  - Benbow, Wystan
A1  - Bird, Ralph
A1  - Bourbeau, E.
A1  - Buchovecky, M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Cerruti, M.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Dwarkadas, Vikram V.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Griffin, S.
A1  - Huetten, M.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kelley-Hoskins, N.
A1  - Kertzman, M.
A1  - Kieda, D.
A1  - Krause, M.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Maier, G.
A1  - McArthur, S.
A1  - McCann, A.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Park, Nahee
A1  - Pohl, Martin
A1  - Popkow, A.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Sadeh, I.
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Shahinyan, K.
A1  - Slane, P.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Trepanier, S.
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Weisgarber, T.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Zitzer, B.
T1  - Gamma-ray Observations of Tycho's Supernova Remnant with VERITAS and Fermi
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
KW  - material
KW  - data behind figure
Y1  - 2017
U6  - https://doi.org/10.3847/1538-4357/836/1/23
SN  - 0004-637X
SN  - 1538-4357
VL  - 836
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Armin, Ardalan
A1  - Durrant, James R.
A1  - Shoaee, Safa
T1  - Interplay Between Triplet-, Singlet-Charge Transfer States and Free Charge Carriers Defining Bimolecular Recombination Rate Constant of Organic Solar Cells
JF  - The journal of physical chemistry : C, Nanomaterials and interfaces
N2  - Despite the myriad of organic donor:acceptor materials, only few systems have emerged in the life of organic solar cells to, exhibit considerable reduced bimolecular recombination, with respect to the random encounter rate given by the Langevin equation. Monte Carlo simulations have revealed that the rate constant of the formation of electron-hole bound states depends on the random encounter of opposite charges and is nearly given by the Langevin equation for the domain sizes relevant to efficient bulk heterojunction systems. Recently, three studies :suggested that charge transfer states dissociating much faster than their decay rate to the ground state, can result in reduced bimolecular recombination by lowering the recombination rate to the ground state as a loss pathway. A separate study identified another loss pathway and suggested that forbidden back electron transfer from triplet charge transfer states to triplet excitons is a key to achieving reduced recombination. Herein we further explain the reduced bimolecular recombination by investigating the limitations of these two proposals. By solving kinetic rate equations for a BHJ system with realistic rates, we show that both of these previously presented conditions must only be held at the same time fora system to exhibit non-Langevin behavior. We demonstrate that suppression of both of the parallel loss channels of singlet and triplet states can be achieved through increasing the dissociation rate of the charge transfer states; a crucial requirement to achieve a high charge carrier extraction efficiency.
Y1  - 2017
U6  - https://doi.org/10.1021/acs.jpcc.7b04825
SN  - 1932-7447
VL  - 121
SP  - 13969
EP  - 13976
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Arora, Ashima
A1  - Mawass, Mohamad-Assaad
A1  - Sandig, Oliver
A1  - Luo, Chen
A1  - Uenal, Ahmet A.
A1  - Radu, Florin
A1  - Valencia, Sergio
A1  - Kronast, Florian
T1  - Spatially resolved investigation of all optical magnetization switching in TbFe alloys
JF  - Scientific reports
N2  - Optical control of magnetization using femtosecond laser without applying any external magnetic field offers the advantage of switching magnetic states at ultrashort time scales. Recently, all-optical helicity-dependent switching (AO-HDS) has drawn a significant attention for potential information and data storage device applications. In this work, we employ element and magnetization sensitive photoemission electron microscopy (PEEM) to investigate the role of heating in AO-HDS for thin films of the rare-earth transition-metal alloy TbFe. Spatially resolved measurements in a 3–5&#8201;&#956;m sized stationary laser spot demonstrate that AO-HDS is a local phenomenon in the vicinity of thermal demagnetization in a ‘ring’ shaped region. The efficiency of AO-HDS further depends on a local temperature profile around the demagnetized region and thermally activated domain wall motion. We also demonstrate that the thickness of the film determines the preferential switching direction for a particular helicity.
Y1  - 2017
U6  - https://doi.org/10.1038/s41598-017-09615-1
SN  - 2045-2322
VL  - 7
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Arrowsmith, J. Ramon
A1  - Crosby, Christopher J.
A1  - Korzhenkov, Andrey M.
A1  - Mamyrov, Ernest
A1  - Povolotskaya, Irina
A1  - Guralnik, Benny
A1  - Landgraf, Angela
T1  - Surface rupture of the 1911 Kebin (Chon-Kemin) earthquake, Northern Tien Shan, Kyrgyzstan
JF  - Seismicity, fault rupture and earthquake hazards in slowly deforming regions
N2  - The 1911 Chon-Kemin (Kebin) earthquake culminated c. 30 years of remarkable earthquakes in the northern Tien Shan (Kyrgyzstan and Kazakhstan). Building on prior mapping of the event, we traced its rupture in the field and measured more than 50 offset landforms. Cumulative fault rupture length is >155-195 km along 13 fault patches comprising six sections. The patches are separated by changes of dip magnitude or dip direction, or by 4-10 km-wide stepovers. One <40 km section overlaps and is parallel to the main north-dipping rupture but is 7 km north and dips opposite (south). Both ends of the rupture are along mountain front thrust faults demonstrating late Quaternary activity. We computed the moment from each fault patch using the surface fault traces, dip inferred from the traces, 20 km seismogenic thickness, rigidity of 3.3 x 10(10) N m(-2) and dip slip converted from our observations of the largely reverse sense of motion vertical offsets. The discontinuous patches with c. 3-4 m average slip and peak slip of <14 m yield a seismic moment of 4.6 x 10(20) Nm (M-w 7.78) to 7.4 x 10(20) Nm (M-w 7.91). The majority of moment was released along the inner eastern rupture segments. This geological moment is lower by a factor of 1.5 from that determined from teleseismic data.
Y1  - 2016
SN  - 978-1-86239-745-3
SN  - 978-1-86239-964-8
U6  - https://doi.org/10.1144/SP432.10
SN  - 0305-8719
VL  - 432
SP  - 233
EP  - 253
PB  - The Geological Society
CY  - London
ER  - 
TY  - JOUR
A1  - Arslan, Seckin
A1  - De Kok, Dörte
A1  - Bastiaanse, Roelien
T1  - Processing grammatical evidentiality and time reference in Turkish heritage and monolingual speakers
JF  - Bilingualism : language and cognition.
KW  - evidentiality
KW  - time reference
KW  - heritage language speaker
KW  - Turkish-Dutch bilingualism
Y1  - 2017
U6  - https://doi.org/10.1017/S136672891500084X
SN  - 1366-7289
SN  - 1469-1841
VL  - 20
SP  - 457
EP  - 472
PB  - Cambridge Univ. Press
CY  - New York
ER  - 
TY  - JOUR
A1  - Arslan, Seckin
A1  - Felser, Claudia
T1  - Comprehension of wh-questions in Turkish-German bilinguals with aphasia
BT  - a dual-case study
JF  - Clinical linguistics & phonetics
N2  - The aim of our study was to examine the extent to which linguistic approaches to sentence comprehension deficits in aphasia can account for differential impairment patterns in the comprehension of wh-questions in bilingual persons with aphasia (PWA). We investigated the comprehension of subject and object wh-questions in both Turkish, a wh-in-situ language, and German, a wh-fronting language, in two bilingual PWA using a sentence-to-picture matching task. Both PWA showed differential impairment patterns in their two languages. SK, an early bilingual PWA, had particular difficulty comprehending subject which-questions in Turkish but performed normal across all conditions in German. CT, a late bilingual PWA, performed more poorly for object which-questions in German than in all other conditions, whilst in Turkish his accuracy was at chance level across all conditions. We conclude that the observed patterns of selective cross-linguistic impairments cannot solely be attributed either to difficulty with wh-movement or to problems with the integration of discourse-level information. Instead our results suggest that differences between our PWA’s individual bilingualism profiles (e.g. onset of bilingualism, premorbid language dominance) considerably affected the nature and extent of their impairments.
KW  - Bilingual aphasia
KW  - wh-questions
KW  - Turkish-German bilingualism
KW  - wh-in-situ
KW  - wh-movement
Y1  - 2017
U6  - https://doi.org/10.1080/02699206.2017.1416493
SN  - 0269-9206
SN  - 1464-5076
VL  - 32
IS  - 7
SP  - 640
EP  - 660
PB  - Taylor & Francis Group
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Arslan, Seçkin
A1  - Gür, Eren
A1  - Felser, Claudia
T1  - Predicting the sources of impaired wh-question comprehension in non-fluent aphasia
BT  - a cross-linguistic machine learning study on Turkish and German
JF  - Cognitive neuropsychology
N2  - This study investigates the comprehension of wh-questions in individuals with aphasia (IWA) speaking Turkish, a non-wh-movement language, and German, a wh-movement language. We examined six German-speaking and 11 Turkish-speaking IWA using picture-pointing tasks. Findings from our experiments show that the Turkish IWA responded more accurately to both object who and object which questions than to subject questions, while the German IWA performed better for subject which questions than in all other conditions. Using random forest models, a machine learning technique used in tree-structured classification, on the individual data revealed that both the Turkish and German IWA’s response accuracy is largely predicted by the presence of overt and unambiguous case marking. We discuss our results with regard to different theoretical approaches to the comprehension of wh-questions in aphasia.
KW  - Non-fluent aphasia
KW  - random forest algorithm
KW  - sentence comprehension
KW  - wh-in-situ
KW  - wh-questions
KW  - wh-movement
Y1  - 2017
U6  - https://doi.org/10.1080/02643294.2017.1394284
SN  - 0264-3294
SN  - 1464-0627
VL  - 34
SP  - 312
EP  - 331
PB  - Taylor & Francis
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Arús, Eugènia
T1  - Education through music ‒ Another way of teaching
BT  - Dalcroze 100 years later
JF  - Potsdamer Schriftenreihe zur Musikpädagogik
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-399287
SN  - 978-3-86956-378-7
SN  - 2196-5080
SN  - 1861-8529
IS  - 4
SP  - 139
EP  - 153
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Aseev, Nikita
A1  - Shprits, Yuri Y.
A1  - Drozdov, Alexander
A1  - Kellerman, Adam C.
A1  - Usanova, Maria E.
A1  - Wang, D.
A1  - Zhelavskaya, Irina
T1  - Signatures of Ultrarelativistic Electron Loss in the Heart of the Outer Radiation Belt Measured by Van Allen Probes
JF  - Journal of geophysical research : Space physics
N2  - Up until recently, signatures of the ultrarelativistic electron loss driven by electromagnetic ion cyclotron (EMIC) waves in the Earth's outer radiation belt have been limited to direct or indirect measurements of electron precipitation or the narrowing of normalized pitch angle distributions in the heart of the belt. In this study, we demonstrate additional observational evidence of ultrarelativistic electron loss that can be driven by resonant interaction with EMIC waves. We analyzed the profiles derived from Van Allen Probe particle data as a function of time and three adiabatic invariants between 9 October and 29 November 2012. New local minimums in the profiles are accompanied by the narrowing of normalized pitch angle distributions and ground&#8208;based detection of EMIC waves. Such a correlation may be indicative of ultrarelativistic electron precipitation into the Earth's atmosphere caused by resonance with EMIC waves.
Y1  - 2017
U6  - https://doi.org/10.1002/2017JA024485
SN  - 2169-9380
SN  - 2169-9402
VL  - 122
SP  - 10102
EP  - 10111
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Atilaw, Yoseph
A1  - Duffy, Sandra
A1  - Heydenreich, Matthias
A1  - Muiva-Mutisya, Lois
A1  - Avery, Vicky M.
A1  - Erdelyi, Mate
A1  - Yenesew, Abiy
T1  - Three Chalconoids and a Pterocarpene from the Roots of Tephrosia aequilata
JF  - Molecules
N2  - In our search for new antiplasmodial agents, the CH2Cl2/CH3OH (1:1) extract of the roots of Tephrosia aequilata was investigated, and observed to cause 100% mortality of the chloroquine-sensitive (3D7) strain of Plasmodium falciparum at a 10 mg/mL concentration. From this extract three new chalconoids, E-2,6-dimethoxy-3,4-(2,2-dimethyl)pyranoretrochalcone (1, aequichalcone A), Z-2,6-dimethoxy-3,4-(2,2-dimethyl)pyranoretrochalcone (2, aequichalcone B), 4-ethoxy-3-hydroxypraecansone B (3, aequichalcone C) and a new pterocarpene, 3,4:8,9-dimethylenedioxy-6a,11a-pterocarpene (4), along with seven known compounds were isolated. The purified compounds were characterized by NMR spectroscopic and mass spectrometric analyses. Compound 1 slowly converts into 2 in solution, and thus the latter may have been enriched, or formed, during the extraction and separation process. The isomeric compounds 1 and 2 were both observed in the crude extract. Some of the isolated constituents showed good to moderate antiplasmodial activity against the chloroquine-sensitive (3D7) strain of Plasmodium falciparum.
KW  - Tephrosia aequilata
KW  - chalcone
KW  - retrochalcone
KW  - aequichalcone A
KW  - aequichalcone B
KW  - aequichalcone C
KW  - pterocarpene
KW  - antiplasmodial
Y1  - 2017
U6  - https://doi.org/10.3390/molecules22020318
SN  - 1420-3049
VL  - 22
IS  - 2
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Attermeyer, Katrin
A1  - Grossart, Hans-Peter
A1  - Flury, Sabine
A1  - Premke, Katrin
T1  - Bacterial processes and biogeochemical changes in the water body of kettle holes - mainly driven by autochthonous organic matter?
JF  - Aquatic sciences : research across boundaries
N2  - Kettle holes are small inland waters formed from glacially-created depressions often situated in agricultural landscapes. Due to their high perimeter-to-area ratio facilitating a high aquatic-terrestrial coupling, kettle holes can accumulate high concentrations of organic carbon and nutrients, fueling microbial activities and turnover rates. Thus, they represent hotspots of carbon turnover in the landscape, but their bacterial activities and controlling factors have not been well investigated. Therefore, we aimed to assess the relative importance of various environmental factors on bacterial and biogeochemical processes in the water column of kettle holes and to disentangle their variations. In the water body of ten kettle holes in north-eastern Germany, we measured several physico-chemical and biological parameters such as carbon quantity and quality, as well as bacterial protein production (BP) and community respiration (CR) in spring, early summer and autumn 2014. Particulate organic matter served as an indicator of autochthonous production and represented an important parameter to explain variations in BP and CR. This notion is supported by qualitative absorbance indices of dissolved molecules in water samples and C: N ratios of the sediments, which demonstrate high fractions of autochthonous organic matter (OM) in the studied kettle holes. In contrast, dissolved chemical parameters were less important for bacterial activities although they revealed strong differences throughout the growing season. Pelagic bacterial activities and dynamics might thus be regulated by autochthonous OM in kettle holes implying a control of important biogeochemical processes by internal primary production rather than facilitated exchange with the terrestrial surrounding due to a high perimeter-to-area ratio.
KW  - Bacterial production
KW  - Carbon turnover
KW  - Growth efficiency
KW  - Ponds
KW  - Respiration
KW  - DOC quality
KW  - LC-OCD
Y1  - 2017
U6  - https://doi.org/10.1007/s00027-017-0528-1
SN  - 1015-1621
SN  - 1420-9055
VL  - 79
SP  - 675
EP  - 687
PB  - Springer
CY  - Basel
ER  - 
TY  - JOUR
A1  - Auyyuenyong, Ratchada
A1  - Henze, Andrea
A1  - Ungru, Julia
A1  - Schweigert, Florian Johannes
A1  - Raila, Jens
A1  - Vervuert, Ingrid
T1  - Determination of lipid profiles in serum of obese ponies before and after weight reduction by using multi-one-dimensional thin-layer chromatography
JF  - Research in veterinary science
N2  - Obesity is a key component of equine metabolic syndrome, which is highly associated with laminitis. Feed restriction and/or exercise are known to alleviate the detrimental effects of insulin resistance in obese ponies. However, little is known about changes in the serum lipid patterns due to weight reduction and its association with disease outcomes. Therefore, the lipid patterns in the serum of 14 mature ponies before and after a 14-week body weight reduction program (BWRP) were investigated by multi-one-dimensional thin-layer chromatography (MOD-TLC). Additionally, sensitivity to insulin (SI), body condition scores (BCS) and cresty neck scores (CNS) were measured. A BWRP resulted in a significant loss of body weight (P < 0.001), which was associated with beneficial decreases in BCS and CNS (both, P < 0.001). Serum lipid compositions revealed significantly increased free fatty acid (FFA), sphingomyelin (SM; both P < 0.001), total cholesterol (C) and cholesterol ester (CE) (both P < 0.01) and triacylglycerol (TG; P < 0.05) densities. Improvement of SI after the BWRP was associated with increases in neutral lipids (C, CE and TG, all P < 0.01), FFA and the phospholipid SM (both, P < 0.001). The results show that a BWRP in obese ponies was effective and associated with changes in the concentrations of neutral lipids and the phospholipid SM, indicating that SM may play a role in insulin signaling pathways and thus in the pathogenesis of insulin resistance and the progression of metabolic syndrome in obese ponies.
KW  - Neutral lipids
KW  - Equine metabolic syndrome
KW  - Phospholipids
KW  - Horse
KW  - Thin layer chromatography
Y1  - 2017
U6  - https://doi.org/10.1016/j.rvsc.2017.11.013
SN  - 0034-5288
SN  - 1532-2661
VL  - 117
SP  - 111
EP  - 117
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Aygül, Mesut
A1  - Oberhänsli, Roland
T1  - Tectonic Stacking of HP/LT Metamorphic Rocks in Accretionary Wedges and the Role of Shallowing Slab-Mantle Decoupling
JF  - Tectonics
N2  - High-pressure/low-temperature (HP/LT) chloritoid-bearing micaschists crop out widely in the central part of northern Turkey and represent deep-seated subduction-accretionary complexes. Three peak metamorphic assemblages are identified in the area studied: (1) garnet-chloritoid-glaucophane with pseudomorphs after lawsonite; (2) chloritoid with pseudomorphs after glaucophane; and (3) chloritoid with pseudomorphs after jadeite in addition to phengite, paragonite, quartz, chlorite, rutile, and apatite. The latter is interpreted as transformation of a chloritoid + glaucophane assemblage to chloritoid + jadeite with increasing pressure; PT modeling indicates similar to 17 and 22-25 kbars for the two peak parageneses. The diversity of peak metamorphic assemblages and the PT estimates suggest that basal accretion occurred at different depths within the wedge. The depth of the basal accretion is possibly controlled by the slab-mantle decoupling depth. Stretching and thinning of the lithospheric fore arc induced by the slab rollback possibly caused shallowing of the slab-mantle decoupling depth which limited depth of the basal accretion from 70-80km to similar to 55km within the subduction channel. A slab-mantle coupling depth-controlled basal accretion may also explain the scarcity of eclogite and high-grade blueschist facies metamorphic rocks in active intraoceanic subduction zones. Because the overriding plate is young and hot in intraoceanic subductions, the slab and mantle are coupled at a relatively shallow depth before eclogitization of the oceanic crust. This prevents accretion and exhumation of eclogite along the subduction channel.
KW  - chloritoid micaschist
KW  - accretionary complex
KW  - slab-mantle decoupling
KW  - basal accretion
Y1  - 2017
U6  - https://doi.org/10.1002/2017TC004689
SN  - 0278-7407
SN  - 1944-9194
VL  - 36
SP  - 2332
EP  - 2346
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Baayen, Harald R.
A1  - Vasishth, Shravan
A1  - Kliegl, Reinhold
A1  - Bates, Douglas
T1  - The cave of shadows: Addressing the human factor with generalized additive mixed models
JF  - Journal of memory and language
KW  - Generalized additive mixed models
KW  - Within-experiment adaptation
KW  - Autocorrelation
KW  - Experimental time series
KW  - Confirmatory versus exploratory data analysis
KW  - Model selection
Y1  - 2017
U6  - https://doi.org/10.1016/j.jml.2016.11.006
SN  - 0749-596X
SN  - 1096-0821
VL  - 94
SP  - 206
EP  - 234
PB  - Elsevier
CY  - San Diego
ER  - 
TY  - JOUR
A1  - Baedke, Jan
A1  - Schöttler, Tobias
T1  - Visual Metaphors in the Sciences
BT  - the Case of Epigenetic Landscape Images
JF  - Journal for General Philosophy of Science
N2  - Recent philosophical analyses of the epistemic dimension of images in the sciences show a certain trend in acknowledging potential roles of these images beyond their merely decorative or pedagogical functions. We argue, however, that this new debate has yet paid little attention to a special type of pictures, we call ‘visual metaphor’, and its versatile heuristic potential in organizing data, supporting communication, and guiding research, modeling, and theory formation. Based on a case study of Conrad Hal Waddington’s epigenetic landscape images in biology, we develop a descriptive framework applicable to heuristic roles of various visual metaphors in the sciences.
KW  - Conrad Hal Waddington
KW  - Epigenetic landscape
KW  - Modelling
KW  - Scientific images
KW  - Theory formation
KW  - Visual metaphor
Y1  - 2017
U6  - https://doi.org/10.1007/s10838-016-9353-9
SN  - 0925-4560
SN  - 1572-8587
VL  - 48
SP  - 173
EP  - 194
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Baes, Marzieh
A1  - Sobolev, Stephan Vladimir
T1  - Mantle Flow as a Trigger for Subduction Initiation: A Missing Element of the Wilson Cycle Concept
JF  - Geochemistry, geophysics, geosystems
N2  - The classical Wilson Cycle concept, describing repeated opening and closing of ocean basins, hypothesizes spontaneous conversion of passive continental margins into subduction zones. This process, however, is impeded by the high strength of passive margins, and it has never occurred in Cenozoic times. Here using thermomechanical models, we show that additional forcing, provided by mantle flow, which is induced by neighboring subduction zones and midmantle slab remnants, can convert a passive margin into a subduction zone. Models suggest that this is a long-term process, thus explaining the lack of Cenozoic examples. We speculate that new subduction zones may form in the next few tens of millions of years along the Argentine passive margin and the U.S. East Coast. Mantle suction force can similarly trigger subduction initiation along large oceanic fracture zones. We propose that new subduction zones will preferentially originate where subduction zones were active in the past, thus explaining the remarkable colocation of subduction zones during at least the last 400 Myr.
Y1  - 2017
U6  - https://doi.org/10.1002/2017GC006962
SN  - 1525-2027
VL  - 18
SP  - 4469
EP  - 4486
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Bailis, Peter
A1  - Dillahunt, Tawanna
A1  - Müller, Stefanie
A1  - Baudisch, Patrick
T1  - Research for Practice: Technology for Underserved Communities; Personal Fabrication
JF  - Communications of the ACM / Association for Computing Machinery
N2  - THIS INSTALLMENT OF Research for Practice provides curated reading guides to technology for underserved communities and to new developments in personal fabrication. First, Tawanna Dillahunt describes design considerations and technology for underserved and impoverished communities. Designing for the more than 1.6 billion impoverished individuals worldwide requires special consideration of community needs, constraints, and context. Her selections span protocols for poor-quality communication networks, community-driven content generation, and resource and public service discovery. Second, Stefanie Mueller and Patrick Baudisch provide an overview of recent advances in personal fabrication (for example, 3D printers).
Y1  - 2017
U6  - https://doi.org/10.1145/3080188
SN  - 0001-0782
SN  - 1557-7317
VL  - 60
SP  - 46
EP  - 49
PB  - Association for Computing Machinery
CY  - New York
ER  - 
TY  - JOUR
A1  - Balderas-Valadez, Ruth Fabiola
A1  - Antunez, E. E.
A1  - Olive-Mendez, Sion Federico
A1  - Pacholski, Claudia
A1  - Campos-Alvarez, Jose
A1  - Bokhimi, Xim
A1  - Agarwal, V.
T1  - Porous silicon pillar and bilayer structure as a nucleation center for the formation of aligned vanadium pentoxide nanorods
JF  - Ceramics International
N2  - Porous silicon single layer (PSM), bilayer (PSB) and pillar (PSP) structures have been evaluated as nucleation centers for vanadium pentoxide (V2O5) crystals. Deposition of vanadium precursor over different substrates (drop casting technique), followed by annealing treatment under Ar-H-2 (5% H-2) atmosphere, induced crystallization of vanadium oxide. With respect to c-Si/SiO2 substrate, V2O5 nanorods with relatively large aspect ratio were formed over and within PSP structures. On the other hand, pores in PSM and PSB were found to be filled with relatively smaller crystals. Additionally, PSB provided a nucleation substrate capable to align the nanocrystals in a preferential orientation, while V2O5 crystals grown on PSP were found to be randomly aligned around the nanoporous pillar microstructure. Nanorods and nanocrystals were identified as V2O5 by temperature-controlled XRD measurements and evidence of their crystalline nature was observed via transmission electron microscopy. A careful analysis of electronic microscopy images allows the identification of the facets composing the ends of the crystals and its corresponding surface free energy has been evaluated employing the Wulff theorem. Such high surface area composite structures have potential applications as cathode material in Lithium-ion batteries.
KW  - Porous silicon
KW  - Vanadium pentoxide
KW  - Nanorods
KW  - Crystallization
KW  - Nanostructures
Y1  - 2017
U6  - https://doi.org/10.1016/j.ceramint.2017.03.114
SN  - 0272-8842
SN  - 1873-3956
VL  - 43
SP  - 8023
EP  - 8030
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Ballato, Paolo
A1  - Cifelli, Francesca
A1  - Heidarzadeh, Ghasem
A1  - Ghassemi, Mohammad R.
A1  - Wickert, Andrew D.
A1  - Hassanzadeh, Jamshid
A1  - Dupont-Nivet, Guillaume
A1  - Balling, Philipp
A1  - Sudo, Masafumi
A1  - Zeilinger, Gerold
A1  - Schmitt, Axel K.
A1  - Mattei, Massimo
A1  - Strecker, Manfred
T1  - Tectono-sedimentary evolution of the northern Iranian Plateau: insights from middle-late Miocene foreland-basin deposits
JF  - Basin research
N2  - Sedimentary basins in the interior of orogenic plateaus can provide unique insights into the early history of plateau evolution and related geodynamic processes. The northern sectors of the Iranian Plateau of the Arabia-Eurasia collision zone offer the unique possibility to study middle-late Miocene terrestrial clastic and volcaniclastic sediments that allow assessing the nascent stages of collisional plateau formation. In particular, these sedimentary archives allow investigating several debated and poorly understood issues associated with the long-term evolution of the Iranian Plateau, including the regional spatio-temporal characteristics of sedimentation and deformation and the mechanisms of plateau growth. We document that middle-late Miocene crustal shortening and thickening processes led to the growth of a basement-cored range (Takab Range Complex) in the interior of the plateau. This triggered the development of a foreland-basin (Great Pari Basin) to the east between 16.5 and 10.7Ma. By 10.7Ma, a fast progradation of conglomerates over the foreland strata occurred, most likely during a decrease in flexural subsidence triggered by rock uplift along an intraforeland basement-cored range (Mahneshan Range Complex). This was in turn followed by the final incorporation of the foreland deposits into the orogenic system and ensuing compartmentalization of the formerly contiguous foreland into several intermontane basins. Overall, our data suggest that shortening and thickening processes led to the outward and vertical growth of the northern sectors of the Iranian Plateau starting from the middle Miocene. This implies that mantle-flow processes may have had a limited contribution toward building the Iranian Plateau in NW Iran.
Y1  - 2017
U6  - https://doi.org/10.1111/bre.12180
SN  - 0950-091X
SN  - 1365-2117
VL  - 29
SP  - 417
EP  - 446
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Balta Beylergil, Sinem
A1  - Beck, Anne
A1  - Deserno, Lorenz
A1  - Lorenz, Robert C.
A1  - Rapp, Michael Armin
A1  - Schlagenhauf, Florian
A1  - Heinz, Andreas
A1  - Obermayer, Klaus
T1  - Dorsolateral prefrontal cortex contributes to the impaired behavioral adaptation in alcohol dependence
JF  - NeuroImage: Clinical : a journal of diseases affecting the nervous system
N2  - Substance-dependent individuals often lack the ability to adjust decisions flexibly in response to the changes in reward contingencies. Prediction errors (PEs) are thought to mediate flexible decision-making by updating the reward values associated with available actions. In this study, we explored whether the neurobiological correlates of PEs are altered in alcohol dependence. Behavioral, and functional magnetic resonance imaging (fMRI) data were simultaneously acquired from 34 abstinent alcohol-dependent patients (ADP) and 26 healthy controls (HC) during a probabilistic reward-guided decision-making task with dynamically changing reinforcement contingencies. A hierarchical Bayesian inference method was used to fit and compare learning models with different assumptions about the amount of task-related information subjects may have inferred during the experiment. Here, we observed that the best-fitting model was a modified Rescorla-Wagner type model, the “double-update” model, which assumes that subjects infer the knowledge that reward contingencies are anti-correlated, and integrate both actual and hypothetical outcomes into their decisions. Moreover, comparison of the best-fitting model's parameters showed that ADP were less sensitive to punishments compared to HC. Hence, decisions of ADP after punishments were loosely coupled with the expected reward values assigned to them. A correlation analysis between the model-generated PEs and the fMRI data revealed a reduced association between these PEs and the BOLD activity in the dorsolateral prefrontal cortex (DLPFC) of ADP. A hemispheric asymmetry was observed in the DLPFC when positive and negative PE signals were analyzed separately. The right DLPFC activity in ADP showed a reduced correlation with positive PEs. On the other hand, ADP, particularly the patients with high dependence severity, recruited the left DLPFC to a lesser extent than HC for processing negative PE signals. These results suggest that the DLPFC, which has been linked to adaptive control of action selection, may play an important role in cognitive inflexibility observed in alcohol dependence when reinforcement contingencies change. Particularly, the left DLPFC may contribute to this impaired behavioral adaptation, possibly by impeding the extinction of the actions that no longer lead to a reward.
KW  - Alcohol dependence
KW  - Prediction error
KW  - Reinforcement learning
KW  - Reversal learning
KW  - Dorsolateral prefrontal cortex
KW  - Decision-making
Y1  - 2017
U6  - https://doi.org/10.1016/j.nicl.2017.04.010
SN  - 2213-1582
VL  - 15
SP  - 80
EP  - 94
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Balzus, Benjamin
A1  - Sahle, Fitsum Feleke
A1  - Hönzke, Stefan
A1  - Gerecke, Christian
A1  - Schumacher, Fabian
A1  - Hedtrich, Sarah
A1  - Kleuser, Burkhard
A1  - Bodmeier, Roland
T1  - Formulation and ex vivo evaluation of polymeric nanoparticles for controlled delivery of corticosteroids to the skin and the corneal epithelium
JF  - European journal of pharmaceutics and biopharmaceutics : EJPB ; official journal of the International Association for Pharmaceutical Technology
N2  - Controlled delivery of corticosteroids using nanoparticles to the skin and corneal epithelium may reduce their side effects and maximize treatment effectiveness. Dexamethasone-loaded ethyl cellulose, Eudragit® RS and ethyl cellulose/Eudragit® RS nanoparticles were prepared by the solvent evaporation method. Dexamethasone release from the polymeric nanoparticles was investigated in vitro using Franz diffusion cells. Drug penetration was also assessed ex vivo using excised human skin. Nanoparticle toxicity was determined by MTT and H2DCFDA assays. Eudragit® RS nanoparticles were smaller and positively charged but had a lower dexamethasone loading capacity (0.3–0.7%) than ethyl cellulose nanoparticles (1.4–2.2%). By blending the two polymers (1:1), small (105 nm), positively charged (+37 mV) nanoparticles with sufficient dexamethasone loading (1.3%) were obtained. Dexamethasone release and penetration significantly decreased with decreasing drug to polymer ratio and increased when Eudragit® RS was blended with ethyl cellulose. Ex vivo, drug release and penetration from the nanoparticles was slower than a conventional cream. The nanoparticles bear no toxicity potentials except ethyl cellulose nanoparticles had ROS generation potential at high concentration. In conclusion, the nanoparticles showed great potential to control the release and penetration of corticosteroids on the skin and mucus membrane and maximize treatment effectiveness.
KW  - Dermal delivery
KW  - Dexamethasone
KW  - Ethyl cellulose
KW  - Eudragit (R) RS
KW  - Ocular delivery
KW  - Polymeric nanoparticle
Y1  - 2017
U6  - https://doi.org/10.1016/j.ejpb.2017.02.001
SN  - 0939-6411
SN  - 1873-3441
VL  - 115
SP  - 122
EP  - 130
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Banbara, Mutsunori
A1  - Kaufmann, Benjamin
A1  - Ostrowski, Max
A1  - Schaub, Torsten H.
T1  - Clingcon: The next generation
JF  - Theory and practice of logic programming
KW  - Constraint Answer Set Programming (CASP)
KW  - Answer Set Programming (ASP)
KW  - Sat Modulo Theories (SMT)
KW  - Constraint Programming (CP)
Y1  - 2017
U6  - https://doi.org/10.1017/S1471068417000138
SN  - 1471-0684
SN  - 1475-3081
VL  - 17
SP  - 408
EP  - 461
PB  - Cambridge Univ. Press
CY  - New York
ER  - 
TY  - JOUR
A1  - Bandara, Lashi
A1  - McIntosh, Alan
A1  - Rosen, Andreas
T1  - Riesz continuity of the Atiyah
BT  - singer dirac operator under perturbations of the metric
JF  - Mathematische Annalen
N2  - We prove that the Atiyah–Singer Dirac operator in L2 depends Riesz continuously on L∞ perturbations of complete metrics g on a smooth manifold. The Lipschitz bound for the map depends on bounds on Ricci curvature and its first derivatives as well as a lower bound on injectivity radius. Our proof uses harmonic analysis techniques related to Calderón’s first commutator and the Kato square root problem. We also show perturbation results for more general functions of general Dirac-type operators on vector bundles.
Y1  - 2017
U6  - https://doi.org/10.1007/s00208-017-1610-7
SN  - 0025-5831
SN  - 1432-1807
VL  - 370
IS  - 1-2
SP  - 863
EP  - 915
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Bansard, Jennifer S.
A1  - Pattberg, Philipp H.
A1  - Widerberg, Oscar
T1  - Cities to the rescue? Assessing the performance of transnational municipal networks in global climate governance
JF  - International environmental agreements: politics, law and economics
N2  - Despite the proliferation and promise of subnational climate initiatives, the institutional architecture of transnational municipal networks (TMNs) is not well understood. With a view to close this research gap, the article empirically assesses the assumption that TMNs are a viable substitute for ambitious international action under the United Nations Framework Convention on Climate Change (UNFCCC). It addresses the aggregate phenomenon in terms of geographical distribution, central players, mitigation ambition and monitoring provisions. Examining thirteen networks, it finds that membership in TMNs is skewed toward Europe and North America while countries from the Global South are underrepresented; that only a minority of networks commit to quantified emission reductions and that these are not more ambitious than Parties to the UNFCCC; and finally that the monitoring provisions are fairly limited. In sum, the article shows that transnational municipal networks are not (yet) the representative, ambitious and transparent player they are thought to be.
KW  - Climate change
KW  - Cities and regions
KW  - Urban politics
KW  - Transnational networks
Y1  - 2017
U6  - https://doi.org/10.1007/s10784-016-9318-9
SN  - 1567-9764
SN  - 1573-1553
VL  - 17
SP  - 229
EP  - 246
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Bareither, Nils
A1  - Scheffel, Andre
A1  - Metz, Johannes
T1  - Distribution of polyploid plants in the common annual Brachypodium distachyon (s.l.) in Israel is not linearly correlated with aridity
JF  - Israel Journal of Plant Sciences
N2  - The ecological benefits of polyploidy are intensely debated. Some authors argue that plants with duplicated chromosome sets (polyploids) are more stress- resistant and superior colonizers and may thus outnumber their low ploidy conspecifics in more extreme habitats. Brachypodium distachyon (sensu lato), for example, a common annual grass in Israel and the entire Mediterranean basin, comprises three cytotypes of differing chromosome numbers that were recently proposed as distinct species. It was suggested that increased aridity increases the occurrence of its polyploid cytotype. Here, we tested at two spatial scales whether polyploid plants of B. distachyon s. l. are more frequently found in drier habitats in Israel. We collected a total of 430 specimens (i) along a largescale climatic gradient with 15 thoroughly selected sites (spanning 114- 954 mm annual rainfall), and (ii) from corresponding Northern (more mesic) and Southern (more arid) hill slopes to assess the micro- climatic difference between contrasting exposures. Cytotypes were then determined via flow cytometry. Polyploid plants comprised 90% of all specimens and their proportion ranged between 0% and 100% per site. However, this proportion was not correlated with aridity along the large- scale gradient, nor were polyploids more frequently found on Southern exposures. Our results show for both spatial scales that increasing aridity is not the principal driver for the distribution of polyploids in B. distachyon s. l. in Israel. Notably, though, diploid plants were restricted essentially to four intermediate sites, while polyploids dominated the most arid and the most mesic sites. This, to some degree, clustered pattern suggests that the distribution of cytotypes is not entirely random and calls for future studies to assess further potential drivers.
KW  - Aridity
KW  - Brachypodium distachyon
KW  - Brachypodium hybridum
KW  - Brachypodium stacei
KW  - cytotype
KW  - exposition
KW  - Israel
KW  - Mediterranean grass species
KW  - polyploidization
KW  - rainfall gradient
KW  - slope aspect
Y1  - 2017
SN  - 0792-9978
SN  - 2223-8980
VL  - 64
SP  - 83
EP  - 92
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Baroni, Gabriele
A1  - Zink, Matthias
A1  - Kumar, Rohini
A1  - Samaniego, Luis
A1  - Attinger, Sabine
T1  - Effects of uncertainty in soil properties on simulated hydrological states and fluxes at different spatio-temporal scales
JF  - Hydrology and earth system sciences : HESS
N2  - Soil properties show high heterogeneity at different spatial scales and their correct characterization remains a crucial challenge over large areas. The aim of the study is to quantify the impact of different types of uncertainties that arise from the unresolved soil spatial variability on simulated hydrological states and fluxes. Three perturbation methods are presented for the characterization of uncertainties in soil properties. The methods are applied on the soil map of the upper Neckar catchment (Germany), as an example. The uncertainties are propagated through the distributed mesoscale hydrological model (mHM) to assess the impact on the simulated states and fluxes. The model outputs are analysed by aggregating the results at different spatial and temporal scales. These results show that the impact of the different uncertainties introduced in the original soil map is equivalent when the simulated model outputs are analysed at the model grid resolution (i.e. 500 m). However, several differences are identified by aggregating states and fluxes at different spatial scales (by subcatchments of different sizes or coarsening the grid resolution). Streamflow is only sensitive to the perturbation of long spatial structures while distributed states and fluxes (e.g. soil moisture and groundwater recharge) are only sensitive to the local noise introduced to the original soil properties. A clear identification of the temporal and spatial scale for which finer-resolution soil information is (or is not) relevant is unlikely to be universal. However, the comparison of the impacts on the different hydrological components can be used to prioritize the model improvements in specific applications, either by collecting new measurements or by calibration and data assimilation approaches. In conclusion, the study underlines the importance of a correct characterization of uncertainty in soil properties. With that, soil maps with additional information regarding the unresolved soil spatial variability would provide strong support to hydrological modelling applications.
Y1  - 2017
U6  - https://doi.org/10.5194/hess-21-2301-2017
SN  - 1027-5606
SN  - 1607-7938
VL  - 21
SP  - 2301
EP  - 2320
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Barthold, Frauke Katrin
A1  - Turner, Benjamin L.
A1  - Elsenbeer, Helmut
A1  - Zimmermann, Alexander
T1  - A hydrochemical approach to quantify the role of return flow in a surface flow-dominated catchment
JF  - Hydrological processes
N2  - Stormflow generation in headwater catchments dominated by subsurface flow has been studied extensively, yet catchments dominated by surface flow have received less attention. We addressed this by testing whether stormflow chemistry is controlled by either (a) the event-water signature of overland flow, or (b) the pre-event water signature of return flow. We used a high-resolution hydrochemical data set of stormflow and end-members of multiple storms in an end-member mixing analysis to determine the number of end-members needed to explain stormflow, characterize and identify potential end-members, calculate their contributions to stormflow, and develop a conceptual model of stormflow. The arrangement and relative positioning of end-members in stormflow mixing space suggest that saturation excess overland flow (26-48%) and return flow from two different subsurface storage pools (17-53%) are both similarly important for stormflow. These results suggest that pipes and fractures are important flow paths to rapidly release stored water and highlight the value of within-event resolution hydrochemical data to assess the full range and dynamics of flow paths.
KW  - EMMA
KW  - hydrochemistry
KW  - overland flow
KW  - return flow
KW  - stormflow generation
Y1  - 2016
U6  - https://doi.org/10.1002/hyp.11083
SN  - 0885-6087
SN  - 1099-1085
VL  - 31
IS  - 5
SP  - 1018
EP  - 1033
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Bauch, Marcel
A1  - Klaper, Matthias
A1  - Linker, Torsten
T1  - Intermediates in the cleavage of endoperoxides
JF  - Journal of physical organic chemistry
N2  - The decomposition of anthracene endoperoxides has been investigated under various conditions. Thermolyses proceed via radical intermediates and afford anthracenes and rearrangement products, depending on the substitution pattern. Interestingly, not only the O-O but also the C-O bond can be cleaved homolytically. Under basic conditions fragmentations take place, affording anthraquinone, and reactive oxygen species. This mechanism explains the often observed decomposition of endoperoxides during work-up. Finally, an acid-catalyzed cleavage has been observed under release of hydrogen peroxide. The results should be interesting for the mechanistic understanding of peroxide decomposition and the endoperoxides might serve as mild sources of reactive oxygen species for future applications. Copyright (C) 2016 John Wiley & Sons, Ltd.
KW  - peroxides
KW  - radicals
KW  - reaction mechanism
KW  - reactive intermediates
Y1  - 2017
U6  - https://doi.org/10.1002/poc.3607
SN  - 0894-3230
SN  - 1099-1395
VL  - 30
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Bauch, Marcel
A1  - Krtitschka, Angela
A1  - Linker, Torsten
T1  - Photooxygenation of oxygen-substituted naphthalenes
JF  - Journal of physical organic chemistry
N2  - The reaction of oxygen-substituted naphthalenes with singlet oxygen (O-1(2)) has been investigated, and labile endoperoxides have been isolated and characterized at -78 degrees C for the first time. Low-temperature kinetics by UV spectroscopy revealed that alkoxy and silyloxy substituents remarkably increase the rate of photooxygenations compared to 1,4-dimethylnaphthalene, whereas acyloxy-substituted acenes are inert towards O-1(2). The reactivities nicely correlate with HOMO energies and free activation energies, which we determined by density functional theory calculations. The lability of the isolated endoperoxides is due to their very fast back reaction to the corresponding naphthalenes even at -20 degrees C under release of O-1(2), making them to superior sources of this reactive species under very mild conditions. Finally, a carbohydrate-substituted naphthalene has been synthesized, which reacts reversibly with O-1(2) and might be applied for enantioselective oxidations in future work.
KW  - kinetics
KW  - labile peroxides
KW  - low-temperature experiments
KW  - naphthalenes
KW  - singlet oxygen
Y1  - 2017
U6  - https://doi.org/10.1002/poc.3734
SN  - 0894-3230
SN  - 1099-1395
VL  - 30
SP  - 6803
EP  - 6813
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Bauer, Daniel
A1  - Werth, Felix
A1  - Ha An Nguyen, 
A1  - Kiecker, Felix
A1  - Eberle, Jürgen
T1  - Critical role of reactive oxygen species (ROS) for synergistic enhancement of apoptosis by vemurafenib and the potassium channel inhibitor TRAM-34 in melanoma cells
JF  - Cell death & disease
N2  - Inhibition of MAP kinase pathways by selective BRAF inhibitors, such as vemurafenib and dabrafenib, have evolved as key therapies of BRAF-mutated melanoma. However, tumor relapse and therapy resistance have remained as major problems, which may be addressed by combination with other pathway inhibitors. Here we identified the potassium channel inhibitor TRAM-34 as highly effective in combination with vemurafenib. Thus apoptosis was significantly enhanced and cell viability was decreased. The combination vemurafenib/TRAM-34 was also effective in vemurafenib-resistant cells, suggesting that acquired resistance may be overcome. Vemurafenib decreased ERK phosphorylation, suppressed antiapoptotic Mcl-1 and enhanced proapoptotic Puma and Bim. The combination resulted in enhancement of proapoptotic pathways as caspase-3 and loss of mitochondrial membrane potential. Indicating a special mechanism of vemurafenib-induced apoptosis, we found strong enhancement of intracellular ROS levels already at 1 h of treatment. The critical role of ROS was demonstrated by the antioxidant vitamin E (alpha-tocopherol), which decreased intracellular ROS as well as apoptosis. Also caspase activation and loss of mitochondrial membrane potential were suppressed, proving ROS as an upstream effect. Thus ROS represents an initial and independent apoptosis pathway in melanoma cells that is of particular importance for vemurafenib and its combination with TRAM-34.
Y1  - 2017
U6  - https://doi.org/10.1038/cddis.2017.6
SN  - 2041-4889
VL  - 8
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Baumbach, Lukas
A1  - Siegmund, Jonatan F.
A1  - Mittermeier, Magdalena
A1  - Donner, Reik Volker
T1  - Impacts of temperature extremes on European vegetation during the growing season
JF  - Biogeosciences
N2  - Temperature is a key factor controlling plant growth and vitality in the temperate climates of the mid-latitudes like in vast parts of the European continent. Beyond the effect of average conditions, the timings and magnitudes of temperature extremes play a particularly crucial role, which needs to be better understood in the context of projected future rises in the frequency and/or intensity of such events. In this work, we employ event coincidence analysis (ECA) to quantify the likelihood of simultaneous occurrences of extremes in daytime land surface temperature anomalies (LSTAD) and the normalized difference vegetation index (NDVI). We perform this analysis for entire Europe based upon remote sensing data, differentiating between three periods corresponding to different stages of plant development during the growing season. In addition, we analyze the typical elevation and land cover type of the regions showing significantly large event coincidences rates to identify the most severely affected vegetation types. Our results reveal distinct spatio-temporal impact patterns in terms of extraordinarily large co-occurrence rates between several combinations of temperature and NDVI extremes. Croplands are among the most frequently affected land cover types, while elevation is found to have only a minor effect on the spatial distribution of corresponding extreme weather impacts. These findings provide important insights into the vulnerability of European terrestrial ecosystems to extreme temperature events and demonstrate how event-based statistics like ECA can provide a valuable perspective on environmental nexuses.
Y1  - 2017
U6  - https://doi.org/10.5194/bg-14-4891-2017
SN  - 1726-4170
SN  - 1726-4189
VL  - 14
SP  - 4891
EP  - 4903
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Beck, Samantha V.
A1  - Carvalho, Gary R.
A1  - Barlow, Axel
A1  - Ruber, Lukas
A1  - Tan, Heok Hui
A1  - Nugroho, Estu
A1  - Wowor, Daisy
A1  - Nor, Siti Azizah Mohd
A1  - Herder, Fabian
A1  - Muchlisin, Zainal A.
A1  - de Bruyn, Mark
T1  - Plio-Pleistocene phylogeography of the Southeast Asian Blue Panchax killifish, Aplocheilus panchax
JF  - PLoS one
Y1  - 2017
U6  - https://doi.org/10.1371/journal.pone.0179557
SN  - 1932-6203
VL  - 12
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Behrendt, Felix Nicolas
A1  - Schlaad, Helmut
T1  - Metathesis polymerization of cystine-based macrocycles
JF  - Polymer Chemistry
N2  - Macrocycles based on L-cystine were synthesized by ring-closing metathesis (RCM) and subsequently polymerized by entropy-driven ring-opening metathesis polymerization (ED-ROMP). Monomer conversion reached similar to 80% in equilibrium and the produced poly (ester-amine-disulfide-alkene)s exhibited apparent molar masses (M-w(app)) of up to 80 kDa and dispersities (D) of similar to 2. The polymers can be further functionalized with acid anhydrides and degraded by reductive cleavage of the main-chain disulfide.
Y1  - 2016
U6  - https://doi.org/10.1039/c6py01864e
SN  - 1759-9954
SN  - 1759-9962
VL  - 8
IS  - 2
SP  - 366
EP  - 369
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Behyari, Mahdi
A1  - Mohajjel, Mohammad
A1  - Sobel, Edward
A1  - Rezaeian, Mahnaz
A1  - Moayyed, Mohssen
A1  - Schmidt, Alexander
T1  - Analysis of exhumation history in Misho Mountains, NW Iran
BT  - insights from structural and apatite fission track data
JF  - Neues Jahrbuch für Geologie und Paläontologie : merged with Neues Jahrbuch für Geol. und Paläont. Monatshefte". Abhandlungen
N2  - The Misho complex in Northwest Iran is a prominent topographic massif bounded by well known active faults. Our new structural analysis of this area indicates that faulting has important role in the exhumation of this complex. The conjugate orientation of the North and South Misho Faults caused uplift in the Misho and exhumation of the Precambrian crystalline basement. Our structural and stratigraphic data shows that rapid uplift could have been initiation since the 21-22 Ma and exhumation rate was about 0.16 to 0.24 km/Ma. To refine this age, we performed U/Pb analysis of detrital zircon from the Upper Red Formation using LA-ICP-MS. We conducted AFT analysis on 6 basement samples from the hanging wall and 1 sample from the Upper Red Formation in the footwall NMF. Uplift in the hanging wall of NMF led to resting of sample 916 marl. This geochronologic and thermochronologic data shows that exhumation in the MC is diachronously along strike and affected by faults. The phase of exhumation is documented in the study area and entire Iranian plateau is related to the final closure of the Neo-Tethys and northward motion of the Arabian Plate.
KW  - Misho complex
KW  - NW Iran
KW  - North Tabriz Fault
KW  - apatite fission track
KW  - exhumation
Y1  - 2017
U6  - https://doi.org/10.1127/njgpa/2017/0642
SN  - 0077-7749
VL  - 283
IS  - 3
SP  - 291
EP  - 308
PB  - Schweizerbart
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Beijersbergen, Chantal M. I.
A1  - Granacher, Urs
A1  - Gaebler, Martijn
A1  - DeVita, Paul
A1  - Hortobagyi, Tibor
T1  - Hip mechanics underlie lower extremity power training-induced increase  in old adults’ fast gait velocity
BT  - the Potsdam Gait Study (POGS)
JF  - Gait & posture
N2  - Methods: As part of the Potsdam Gait Study (POGS), healthy old adults completed a no-intervention control period (69.1 +/- 4A yrs, n =14) or a power training program followed by detraining (72.9 +/- 5.4 yrs, n = 15).We measured isokinetic knee extensor and plantarflexor power and measured hip, knee and ankle kinetics at habitual, fast and standardized walking speeds. Results: Power training significantly increased isokinetic knee extensor power (25%), plantarflexor power (43%), and fast gait velocity (5.9%). Gait mechanics underlying the improved fast gait velocity included increases in hip angular impulse (29%) and H1 work (37%) and no changes in positive knee (K2) and A2 work. Detraining further improved fast gait velocity (4.7%) with reductions in H1(-35%), and increases in K2 (36%) and A2 (7%). Conclusion: Power training increased fast gait velocity in healthy old adults by increasing the reliance on hip muscle function and thus further strengthened the age-related distal-to-proximal shift in muscle function. (C) 2016 Elsevier B.V. All rights reserved.
KW  - Walking
KW  - Biomechanics
KW  - Detraining
KW  - Muscle
KW  - Exercise
Y1  - 2017
U6  - https://doi.org/10.1016/j.gaitpost.2016.12.024
SN  - 0966-6362
SN  - 1879-2219
VL  - 52
SP  - 338
EP  - 344
PB  - Elsevier
CY  - Clare
ER  - 
TY  - JOUR
A1  - Beijersbergen, Chantal M. I.
A1  - Granacher, Urs
A1  - Gäbler, Martijn
A1  - Devita, Paul
A1  - Hortobagyi, Tibor
T1  - Power Training-induced Increases in Muscle Activation during Gait in Old Adults
JF  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
N2  - Introduction/Purpose: Aging modifies neuromuscular activation of agonist and antagonist muscles during walking. Power training can evoke adaptations in neuromuscular activation that underlie gains in muscle strength and power but it is unknown if these adaptations transfer to dynamic tasks such as walking. We examined the effects of lower-extremity power training on neuromuscular activation during level gait in old adults. Methods: Twelve community-dwelling old adults (age >= 65 yr) completed a 10-wk lower-extremity power training program and 13 old adults completed a 10-wk control period. Before and after the interventions, we measured maximal isometric muscle strength and electromyographic (EMG) activation of the right knee flexor, knee extensor, and plantarflexor muscles on a dynamometer and we measured EMG amplitudes, activation onsets and offsets, and activation duration of the knee flexors, knee extensors, and plantarflexors during gait at habitual, fast, and standardized (1.25 +/- 0.6 m.s(-1)) speeds. Results: Power training-induced increases in EMG amplitude (similar to 41%; 0.47 <= d <= 1.47; P <= 0.05) explained 33% (P = 0.049) of increases in isometric muscle strength (similar to 43%; 0.34 <= d <= 0.80; P <= 0.05). Power training-induced gains in plantarflexor activation during push-off (+11%; d = 0.38; P = 0.045) explained 57% (P = 0.004) of the gains in fast gait velocity (+4%; d = 0.31; P = 0.059). Furthermore, power training increased knee extensor activation (similar to 18%; 0.26 <= d <= 0.29; P <= 0.05) and knee extensor coactivation during the main knee flexor burst (similar to 24%, 0.26 <= d <= 0.44; P <= 0.05) at habitual and fast speed but these adaptations did not correlate with changes in gait velocity. Conclusions: Power training increased neuromuscular activation during isometric contractions and level gait in old adults. The power training-induced neuromuscular adaptations were associated with increases in isometric muscle strength and partly with increases in fast gait velocity.
KW  - WALKING
KW  - MUSCLE
KW  - EXERCISE
KW  - EMG
Y1  - 2017
U6  - https://doi.org/10.1249/MSS.0000000000001345
SN  - 0195-9131
SN  - 1530-0315
VL  - 49
SP  - 2198
EP  - 2205
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Bemer, Marian
A1  - van Mourik, Hilda
A1  - Muino, Jose M.
A1  - Ferrandiz, Cristina
A1  - Kaufmann, Kerstin
A1  - Angenent, Gerco C.
T1  - FRUITFULL controls SAUR10 expression and regulates Arabidopsis growth and architecture
JF  - Journal of experimental botany
N2  - MADS-domain transcription factors are well known for their roles in plant development and regulate sets of downstream genes that have been uncovered by high-throughput analyses. A considerable number of these targets are predicted to function in hormone responses or responses to environmental stimuli, suggesting that there is a close link between developmental and environmental regulators of plant growth and development. Here, we show that the Arabidopsis MADS-domain factor FRUITFULL (FUL) executes several functions in addition to its noted role in fruit development. Among the direct targets of FUL, we identified SMALL AUXIN UPREGULATED RNA 10 (SAUR10), a growth regulator that is highly induced by a combination of auxin and brassinosteroids and in response to reduced R:FR light. Interestingly, we discovered that SAUR10 is repressed by FUL in stems and inflorescence branches. SAUR10 is specifically expressed at the abaxial side of these branches and this localized activity is influenced by hormones, light conditions and by FUL, which has an effect on branch angle. Furthermore, we identified a number of other genes involved in hormone pathways and light signalling as direct targets of FUL in the stem, demonstrating a connection between developmentally and environmentally regulated growth programs.
KW  - Architecture
KW  - auxin
KW  - branching
KW  - FRUITFULL
KW  - growth
KW  - hormones
KW  - light response
KW  - MADS-box transcription factor
KW  - SAUR
Y1  - 2017
U6  - https://doi.org/10.1093/jxb/erx184
SN  - 0022-0957
SN  - 1460-2431
VL  - 68
SP  - 3391
EP  - 3403
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Bendjeddou, Mohammed Lamine
A1  - Loumassine, Hibat Allah
A1  - Scheffler, Ingo
A1  - Bouslama, Zihad
A1  - Amr, Zuhair
T1  - Bat ectoparasites (Nycteribiidae, Streblidae, Siphonaptera, Heteroptera, Mesostigmata, Argasidae, and Ixodidae) from Algeria
JF  - Journal of Vector Ecology
N2  - Twenty two species of ectoparasites (Family Nycteribiidae: Nycteribia (Listropoda) schmidlii schmidlii, Nycteribia (Nycteribia) latreillii, Nycteribia (Nycteribia) pedicularia, Penicillidia (Penicillidia) dufourii, and Phthiridium biarticulatum; Family Streblidae: Brachytarsina (Brachytarsina) flavipennis and Raymondia huberi; Order Siphonaptera: Rhinolophopsylla unipectinata arabs, Nycteridopsylla longiceps, Araeopsylla gestroi, Ischnopsyllus intermedius, and Ischnopsyllus octactenus; Order Heteroptera: Cimex pipistrelli, Cimex lectularius, and Cacodmus vicinus; Class Arachnida: Order Mesostigmata: Spinturnix myoti and Eyndhovenia euryalis; Order Ixodida: Family Argasidae: Argas transgariepinus and Argas vespertilionis; Family Ixodidae: Hyalomma dromedarii, Ixodes ricinus, and Ixodes vespertilionis) were recovered from 19 bat species in Algeria. New host records for bats are recorded for the first time: N. schmidlii from Rh. clivosus and R. cystops; N. latreillii from Rh. blasii and P. gaisleri; R. huberi from Rh. clivosus; C. pipistrelli from E. isabellinus and H. savii; C. vicinus from E. isabellinus; S. myoti from P. gaisleri; E. euryalis from P. gaisleri and Rh. blasii; A. vespertilionis from P. gaisleri; I. ricinus from T. teniotis and Rh. hipposideros and H. dromedarii from P. kuhlii. Raymondia huberi is recorded for the first time from Algeria.
KW  - Bats
KW  - Nycteribiidae
KW  - Streblidae
KW  - Siphonaptera
KW  - Heteroptera
KW  - Mesostigmata
KW  - Argasidae
KW  - Ixodidae
KW  - Algeria
Y1  - 2017
U6  - https://doi.org/10.1111/jvec.12235
SN  - 1948-7134
VL  - 42
SP  - 13
EP  - 23
PB  - Wiley Interscience
CY  - Hoboken, NJ
ER  - 
TY  - JOUR
A1  - Benduhn, Johannes
A1  - Tvingstedt, Kristofer
A1  - Piersimoni, Fortunato
A1  - Ullbrich, Sascha
A1  - Fan, Yeli
A1  - Tropiano, Manuel
A1  - McGarry, Kathryn A.
A1  - Zeika, Olaf
A1  - Riede, Moritz K.
A1  - Douglas, Christopher J.
A1  - Barlow, Stephen
A1  - Marder, Seth R.
A1  - Neher, Dieter
A1  - Spoltore, Donato
A1  - Vandewal, Koen
T1  - Intrinsic non-radiative voltage losses in fullerene-based organic solar cells
JF  - Nature Energy
N2  - Organic solar cells demonstrate external quantum efficiencies and fill factors approaching those of conventional photovoltaic technologies. However, as compared with the optical gap of the absorber materials, their open-circuit voltage is much lower, largely due to the presence of significant non-radiative recombination. Here, we study a large data set of published and new material combinations and find that non-radiative voltage losses decrease with increasing charge-transfer-state energies. This observation is explained by considering non-radiative charge-transfer-state decay as electron transfer in the Marcus inverted regime, being facilitated by a common skeletal molecular vibrational mode. Our results suggest an intrinsic link between non-radiative voltage losses and electron-vibration coupling, indicating that these losses are unavoidable. Accordingly, the theoretical upper limit for the power conversion efficiency of single-junction organic solar cells would be reduced to about 25.5% and the optimal optical gap increases to (1.45-1.65) eV, that is, (0.2-0.3) eV higher than for technologies with minimized non-radiative voltage losses.
Y1  - 2017
U6  - https://doi.org/10.1038/nenergy.2017.53
SN  - 2058-7546
VL  - 2
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Bengfort, Michael
A1  - van Velzen, Ellen
A1  - Gaedke, Ursula
T1  - Slight phenotypic variation in predators and prey causes complex predator-prey oscillations
JF  - Ecological Complexity
N2  - Predator-prey oscillations are expected to show a 1/4-phase lag between predator and prey. However, observed dynamics of natural or experimental predator-prey systems are often more complex. A striking but hardly studied example are sudden interruptions of classic 1/4-lag cycles with periods of antiphase oscillations, or periods without any regular predator-prey oscillations. These interruptions occur for a limited time before the system reverts to regular 1/4-lag oscillations, thus yielding intermittent cycles. Reasons for this behaviour are often difficult to reveal in experimental systems. Here we test the hypothesis that such complex dynamical behaviour may result from minor trait variation and trait adaptation in both the prey and predator, causing recurrent small changes in attack rates that may be hard to capture by empirical measurements. Using a model structure where the degree of trait variation in the predator can be explicitly controlled, we show that a very limited amount of adaptation resulting in 10-15% temporal variation in attack rates is already sufficient to generate these intermittent dynamics. Such minor variation may be present in experimental predator-prey systems, and may explain disruptions in regular 1/4-lag oscillations.
KW  - Predator-prey cycles
KW  - Phase relationships
KW  - Intermittent cycles
KW  - Adaptive traits
KW  - Eco-evolutionary dynamics
KW  - Complex dynamics
Y1  - 2017
U6  - https://doi.org/10.1016/j.ecocom.2017.06.003
SN  - 1476-945X
SN  - 1476-9840
VL  - 31
SP  - 115
EP  - 124
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Benini, Marco
A1  - Capoferri, Matteo
A1  - Dappiaggi, Claudio
T1  - Hadamard States for Quantum Abelian Duality
JF  - Annales de l'Institut Henri Poincaré
N2  - Abelian duality is realized naturally by combining differential cohomology and locally covariant quantum field theory. This leads to a -algebra of observables, which encompasses the simultaneous discretization of both magnetic and electric fluxes. We discuss the assignment of physically well-behaved states on this algebra and the properties of the associated GNS triple. We show that the algebra of observables factorizes as a suitable tensor product of three -algebras: the first factor encodes dynamical information, while the other two capture topological data corresponding to electric and magnetic fluxes. On the former factor and in the case of ultra-static globally hyperbolic spacetimes with compact Cauchy surfaces, we exhibit a state whose two-point correlation function has the same singular structure of a Hadamard state. Specifying suitable counterparts also on the topological factors, we obtain a state for the full theory, ultimately implementing Abelian duality transformations as Hilbert space isomorphisms.
Y1  - 2017
U6  - https://doi.org/10.1007/s00023-017-0593-y
SN  - 1424-0637
SN  - 1424-0661
VL  - 18
SP  - 3325
EP  - 3370
PB  - Springer
CY  - Basel
ER  - 
TY  - JOUR
A1  - Benini, Marco
A1  - Schenkel, Alexander
T1  - Quantum Field Theories on Categories Fibered in Groupoids
JF  - Communications in mathematical physics
N2  - We introduce an abstract concept of quantum field theory on categories fibered in groupoids over the category of spacetimes. This provides us with a general and flexible framework to study quantum field theories defined on spacetimes with extra geometric structures such as bundles, connections and spin structures. Using right Kan extensions, we can assign to any such theory an ordinary quantum field theory defined on the category of spacetimes and we shall clarify under which conditions it satisfies the axioms of locally covariant quantum field theory. The same constructions can be performed in a homotopy theoretic framework by using homotopy right Kan extensions, which allows us to obtain first toy-models of homotopical quantum field theories resembling some aspects of gauge theories.
Y1  - 2017
U6  - https://doi.org/10.1007/s00220-017-2986-7
SN  - 0010-3616
SN  - 1432-0916
VL  - 356
SP  - 19
EP  - 64
PB  - Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Benini, Marco
A1  - Schenkel, Alexander
T1  - Poisson Algebras for Non-Linear Field Theories in the Cahiers Topos
JF  - Annales de l'Institut Henri Poincaré
Y1  - 2017
U6  - https://doi.org/10.1007/s00023-016-0533-2
SN  - 1424-0637
SN  - 1424-0661
VL  - 18
SP  - 1435
EP  - 1464
PB  - Springer
CY  - Basel
ER  - 
TY  - JOUR
A1  - Bents, Dominik
A1  - Rybak, Alexander
A1  - Groth, Detlef
T1  - Spatial conscript body height correlation of Norwegian districts in the 19th century
JF  - Anthropologischer Anzeiger : journal of biological and clinical anthropology ; Mitteilungsorgan der Gesellschaft für Anthropologie
N2  - Background: We investigated height of Norwegian conscripts in view of the hypothesis of a "community effect on height" using autocorrelation analysis of district heights within a time-span of 20 years at the end of the 19th century and correlations between neighboring districts at this time. Material and methods: After digitalizing available body height data of Norwegian draftees in 1877-1878, 1880 (averaged as 1878), and 1895-1897 (averaged as 1896) we calculated the magnitude of autocorrelation of body height within the same municipality at different time points. Furthermore, we generated three different neighborhood networks, (1) based on Euclidean distances, (2) a minimum spanning tree build on those distances, (3) a network founded on real world road connections. The networks were used to determine the correlation between body height of neighboring districts depending on the number of edges required to connect two municipalities. Results: The autocorrelation value for body heights was around r = 0.5 (for all p < 0.001) in the years 1878 and 1896. The correlation between neighboring districts varied in the Euclidean distance based network between 0.47 and 0.27 approximately for both years in a sorted order, descending from nearest (0-50 km) to farthest (150-200 km, for all p < 0.001). First order neighbors in the minimum spanning tree network correlation was 0.36 in 1878 and 0.42 in 1896 (for all p < 0.001). The values of neighbor correlation in the road connection based network ranged in 1878 from 0.42 (first order neighbors) to 0.17 (forth order neighbors, for all p < 0.01) and in 1896 from 0.46 (first order neighbors) to 0.12 (forth order neighbors, for all p < 0.05). Conclusion: This initial study of Norwegian conscript height data from the 19th century showed significant medium sized effects for the within district autocorrelation between 1878 and 1896 as well as medium neighborhood correlation, slightly lower in comparison to a recent study regarding Swiss conscripts. Digitalizing more data from other years in this and later time spans as well as using older road and ship connections instead of the actual road data might stabilize and improve those findings.
KW  - body height
KW  - correlation
KW  - Norway
KW  - conscripts
KW  - community effect on height
Y1  - 2017
U6  - https://doi.org/10.1127/anthranz/2017/0700
SN  - 0003-5548
SN  - 2363-7099
VL  - 74
IS  - 1
SP  - 65
EP  - 69
PB  - Schweizerbart
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Berger, Beatrice
A1  - Baldermann, Susanne
A1  - Ruppel, Silke
T1  - The plant growth-promoting bacterium Kosakonia radicincitans improves fruit yield and quality of Solanum lycopersicum
JF  - Journal of the Science of Food and Agriculture
N2  - BACKGROUNDProduction and the quality of tomato fruits have a strong economic relevance. Microorganisms such as the plant growth-promoting bacterium (PGPB) Kosakonia radicincitans (DSM 16656) have been demonstrated to improve shoot and root growth of young tomato plants, but data on yield increase and fruit quality by K. radicincitans are lacking. RESULTSThis study investigated how K. radicincitans affects tomato fruits. After inoculation of tomato seeds with K. radicincitans or a sodium chloride buffer control solution, stalk length, first flowering and the amount of ripened fruits produced by inoculated and non-inoculated plants were monitored over a period of 21 weeks. Inoculation of tomato seeds with K. radicincitans accelerated flowering and ripening of tomato fruits. Sugars, acidity, amino acids, volatile organic compounds and carotenoids in the fruits were also analyzed. CONCLUSIONIt was found that the PGPBK. radicincitans affected the amino acid, sugar and volatile composition of ripened fruits, contributing to a more pleasant-tasting fruit without forfeiting selected quality indicators. (c) 2017 Society of Chemical Industry
KW  - plant growth-promoting bacteria
KW  - Kosakonia radicincitans
KW  - fruit metabolites
KW  - Solanum lycopersicum
Y1  - 2017
U6  - https://doi.org/10.1002/jsfa.8357
SN  - 0022-5142
SN  - 1097-0010
VL  - 97
SP  - 4865
EP  - 4871
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Bergholz, Kolja
A1  - May, Felix
A1  - Giladi, Itamar
A1  - Ristow, Michael
A1  - Ziv, Yaron
A1  - Jeltsch, Florian
T1  - Environmental heterogeneity drives fine-scale species assembly and functional diversity of annual plants in a semi-arid environment
JF  - Perspectives in plant ecology, evolution and systematics
N2  - Spatial environmental heterogeneity is considered a fundamental factor for the maintenance of plant species richness. However, it still remains unclear whether heterogeneity may also facilitate coexistence at fine grain sizes or whether other processes, like mass effects and source sink dynamics due to dispersal, control species composition and diversity at these scales. In this study, we used two complimentary analyses to identify the role of heterogeneity within 15 m x 15 m plots for the coexistence of species-rich annual communities in a semi-arid environment along a steep precipitation gradient. Specifically, we: (a) analyzed the effect of environmental heterogeneity on species, functional and phylogenetic diversity within microsites (alpha diversity, 0.06 m(2) and 1 m(2)), across microsites (beta diversity), and diversity at the entire plot (gamma diversity); (b) further we used two null models to detect non-random trait and phylogenetic patterns in order to infer assembly processes, i.e. whether co-occurring species tend to share similar traits (trait convergence) or dissimilar traits (trait divergence). In general, our results showed that heterogeneity had a positive effect on community diversity. Specifically, for alpha diversity, the effect was significant for functional diversity, and not significant for either species or phylogenetic diversities. For beta diversity, all three measures of community diversity (species, functional, and phylogenetic) increased significantly, as they also did for gamma diversity, where functional measures were again stronger than for species or phylogenetic measures. In addition, the null model approach consistently detected trait convergence, indicating that species with similar traits tended to co-occur and had high abundances in a given microsite. While null model analysis across the phylogeny partly supported these trait findings, showing phylogenetic underdispersion at the 1m(2) grain size, surprisingly when species abundances in microsites were analyzed they were more evenly distributed across the phylogenetic tress than expected (phylogenetic overdispersion). In conclusion, our results provide compelling support that environmental heterogeneity at a relatively fine scale is an important factor for species co-existence as it positively affects diversity as well as influences species assembly. Our study underlines the need for trait-based approaches conducted at fine grain sizes in order to better understand species coexistence and community assembly. (C) 2017 Elsevier GmbH. All rights reserved.
KW  - Community assembly
KW  - Plant functional trait
KW  - Habitat heterogeneity
KW  - Limiting similarity
KW  - Environmental filtering
KW  - Heterogeneity species diversity relationship
Y1  - 2017
U6  - https://doi.org/10.1016/j.ppees.2017.01.001
SN  - 1433-8319
VL  - 24
SP  - 138
EP  - 146
PB  - Elsevier
CY  - Jena
ER  - 
TY  - JOUR
A1  - Bergholz, Kolja
A1  - May, Felix
A1  - Ristow, Michael
A1  - Giladi, Itamar
A1  - Ziv, Yaron
A1  - Jeltsch, Florian
T1  - Two Mediterranean annuals feature high within-population trait variability and respond differently to a precipitation gradient
JF  - Basic and applied ecology : Journal of the Gesellschaft für Ökologie
N2  - Intraspecific trait variability plays an important role in species adaptation to climate change. However, it still remains unclear how plants in semi-arid environments respond to increasing aridity. We investigated the intraspecific trait variability of two common Mediterranean annuals (Geropogon hybridus and Crupina crupinastrum) with similar habitat preferences. They were studied along a steep precipitation gradient in Israel similar to the maximum predicted precipitation changes in the eastern Mediterranean basin (i.e. -30% until 2100). We expected a shift from competitive ability to stress tolerance with decreasing precipitation and tested this expectation by measuring key functional traits (canopy and seed release height, specific leaf area, N-and P-leaf content, seed mass). Further, we evaluated generative bet-hedging strategies by different seed traits. Both species showed different responses along the precipitation gradient. C. crupinastrum exhibited only decreased plant height toward saridity, while G. hybridus showed strong trends of generative adaptation to aridity. Different seed trait indices suggest increased bet-hedging of G. hybridus in arid environments. However, no clear trends along the precipitation gradient were observed in leaf traits (specific leaf area and leaf N-/P-content) in both species. Moreover, variance decomposition revealed that most of the observed trait variation (>> 50%) is found within populations. The findings of our study suggest that responses to increased aridity are highly species-specific and local environmental factors may have a stronger effect on intraspecific trait variation than shifts in annual precipitation. We therefore argue that trait-based analyses should focus on precipitation gradients that are comparable to predicted precipitation changes and compare precipitation effects to effects of local environmental factors. (C) 2017 Gesellschaft fur Okologie. Published by Elsevier GmbH. All rights reserved.
KW  - Climate change
KW  - Functional ecology
KW  - Plant height
KW  - Drought stress
KW  - Rainfall gradient
KW  - Trait-environment relationship
KW  - Local adaptation
KW  - Phenotypic plasticity
Y1  - 2017
U6  - https://doi.org/10.1016/j.baae.2017.11.001
SN  - 1439-1791
SN  - 1618-0089
VL  - 25
SP  - 48
EP  - 58
PB  - Elsevier
CY  - Jena
ER  - 
TY  - JOUR
A1  - Bernacchioni, Caterina
A1  - Ghini, Veronica
A1  - Cencetti, Francesca
A1  - Japtok, Lukasz
A1  - Donati, Chiara
A1  - Bruni, Paola
A1  - Turano, Paola
T1  - NMR metabolomics highlights sphingosine kinase-1 as a new molecular switch in the orchestration of aberrant metabolic phenotype in cancer cells
JF  - Molecular oncology / Federation of European Biochemical Societies
N2  - Strong experimental evidence in animal and cellular models supports a pivotal role of sphingosine kinase-1 (SK1) in oncogenesis. In many human cancers, SK1 levels are upregulated and these increases are linked to poor prognosis in patients. Here, by employing untargeted NMR- based metabolomic profiling combined with functional validations, we report the crucial role of SK1 in the metabolic shift known as the Warburg effect in A2780 ovarian cancer cells. Indeed, expression of SK1 induced a high glycolytic rate, characterized by increased levels of lactate along with increased expression of the proton/monocarboxylate symporter MCT1, and decreased oxidative metabolism, associated with the accumulation of intermediates of the tricarboxylic acid cycle and reduction in CO2 production. Additionally, SK1-expressing cells displayed a significant increase in glucose uptake paralleled by GLUT3 transporter upregulation. The role of SK1 is not limited to the induction of aerobic glycolysis, affecting metabolic pathways that appear to support the biosynthesis of macromolecules. These findings highlight the role of SK1 signaling axis in cancer metabolic reprogramming, pointing out innovative strategies for cancer therapies.
KW  - NMR-based metabolomics
KW  - ovarian cancer
KW  - sphingosine kinase-1
KW  - Warburg effect
Y1  - 2017
U6  - https://doi.org/10.1002/1878-0261.12048
SN  - 1878-0261
VL  - 11
SP  - 517
EP  - 533
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Bernardez, Patricia
A1  - Prego, Ricardo
A1  - Virginia Filgueiras, Ana
A1  - Ospina-Alvarez, Natalia
A1  - Santos-Echeandia, Juan
A1  - Angel Alvarez-Vazquez, Miguel
A1  - Caetano, Miguel
T1  - Lithogenic sources, composition and intra-annual variability of suspended particulate matter supplied from rivers to the Northern Galician Rias (Bay of Biscay)
JF  - Journal of sea research
N2  - Scarce research about small European rivers from non-human impacted areas to determine their natural background state has been undertaken. During the annual hydrological cycle of 2008-9 the patterns of particulate supply (SPM, POC, PON, Al, Cd, Co, Cr, Cu, Fe, Ni, Pb, V, Zn) from the rivers Sor, Mera Landro, Lourido and Landoi to the Northern Galician Rias (SW Bay of Biscay) were tackled. No differences in the composition of the SPM were detected for the studied rivers regarding Al, Fe and POC but the relative percentage of particulate trace elements (PTE) discriminate the rivers. So, Cr, Co and Ni in the Lourido, and Landoi rivers, and Cu in the Mera River, are controlled by watershed minerals of Ortegal Geological Complex while for the rest rivers PTE are by granitic and Ollo de Sapo bedrock watershed. Therefore, the imprint of PTE in the parental rocks of the river basins is reflected on the coastal sediments of the Rias. The main process controlling the dynamics and variations of chemical elements in the particulate form is the river discharge. This fact exemplifies that these rivers presents a natural behavior not being highly influenced by anthropogenic activities.
KW  - SPM
KW  - Trace metals
KW  - Organic matter
KW  - River
KW  - W Cantabrian coast
Y1  - 2017
U6  - https://doi.org/10.1016/j.seares.2017.05.006
SN  - 1385-1101
SN  - 1873-1414
VL  - 130
SP  - 73
EP  - 84
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Bernhardt, Anne
A1  - Schwanghart, Wolfgang
A1  - Hebbeln, Dierk
A1  - Stuut, Jan-Berend W.
A1  - Strecker, Manfred
T1  - Immediate propagation of deglacial environmental change to deep-marine turbidite systems along the Chile convergent margin
JF  - Earth & planetary science letters
N2  - Understanding how Earth-surface processes respond to past climatic perturbations is crucial for making informed predictions about future impacts of climate change on sediment "uxes. Sedimentary records provide the archives for inferring these processes, but their interpretation is compromised by our incomplete understanding of how sediment-routing systems respond to millennial-scale climate cycles. We analyzed seven sediment cores recovered from marine turbidite depositional sites along the Chile continental margin. The sites span a pronounced arid-to-humid gradient with variable relief and related sediment connectivity of terrestrial and marine environments. These sites allowed us to study event related depositional processes in different climatic and geomorphic settings from the Last Glacial Maximum to the present day. The three sites reveal a steep decline of turbidite deposition during deglaciation. High rates of sea-level rise postdate the decline in turbidite deposition. Comparison with paleoclimate proxies documents that the spatio-temporal sedimentary pattern rather mirrors the deglacial humidity decrease and concomitant warming with no resolvable lag times. Our results let us infer that declining deglacial humidity decreased "uvial sediment supply. This signal propagated rapidly through the highly connected systems into the marine sink in north-central Chile. In contrast, in south-central Chile, connectivity between the Andean erosional zone and the "uvial transfer zone probably decreased abruptly by sediment trapping in piedmont lakes related to deglaciation, resulting in a sudden decrease of sediment supply to the ocean. Additionally, reduced moisture supply may have contributed to the rapid decline of turbidite deposition. These different causes result in similar depositional patterns in the marine sinks. We conclude that turbiditic strata may constitute reliable recorders of climate change across a wide range of climatic zones and geomorphic conditions. However, the underlying causes for similar signal manifestations in the sinks may differ, ranging from maintained high system connectivity to abrupt connectivity loss. (C) 2017 Elsevier B.V. All rights reserved.
KW  - signal propagation
KW  - turbidity currents
KW  - Chile
KW  - sediment-routing system connectivity
KW  - Last Glacial Maximum
Y1  - 2017
U6  - https://doi.org/10.1016/j.epsl.2017.05.017
SN  - 0012-821X
SN  - 1385-013X
VL  - 473
SP  - 190
EP  - 204
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Berry, Scott
A1  - Rosa, Stefanie
A1  - Howard, Martin
A1  - Buhler, Marc
A1  - Dean, Caroline
T1  - Disruption of an RNA-binding hinge region abolishes LHP1-mediated epigenetic repression
JF  - Genes & Development
N2  - Epigenetic maintenance of gene repression is essential for development. Polycomb complexes are central to this memory, but many aspects of the underlying mechanism remain unclear. LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) binds Polycomb-deposited H3K27me3 and is required for repression of many Polycomb target genes in Arabidopsis. Here we show that LHP1 binds RNA in vitro through the intrinsically disordered hinge region. By independently perturbing the RNA-binding hinge region and H3K27me3 (trimethylation of histone H3 at Lys27) recognition, we found that both facilitate LHP1 localization and H3K27me3 maintenance. Disruption of the RNAbinding hinge region also prevented formation of subnuclear foci, structures potentially important for epigenetic repression.
KW  - chromatin
KW  - epigenetics
KW  - plant biology
KW  - Polycomb
KW  - RNA
Y1  - 2017
U6  - https://doi.org/10.1101/gad.305227.117
SN  - 0890-9369
SN  - 1549-5477
VL  - 31
SP  - 2115
EP  - 2120
PB  - Cold Spring Harbor Laboratory Press
CY  - Cold Spring Harbor, NY
ER  - 
TY  - JOUR
A1  - Beta, Carsten
A1  - Kruse, Karsten
T1  - Intracellular oscillations and waves
JF  - Annual review of condensed matter physics
N2  - Dynamic processes in living cells are highly organized in space and time. Unraveling the underlying molecular mechanisms of spatiotemporal pattern formation remains one of the outstanding challenges at the interface between physics and biology. A fundamental recurrent pattern found in many different cell types is that of self-sustained oscillations. They are involved in a wide range of cellular functions, including second messenger signaling, gene expression, and cytoskeletal dynamics. Here, we review recent developments in the field of cellular oscillations and focus on cases where concepts from physics have been instrumental for understanding the underlying mechanisms. We consider biochemical and genetic oscillators as well as oscillations that arise from chemo-mechanical coupling. Finally, we highlight recent studies of intracellular waves that have increasingly moved into the focus of this research field.
KW  - self-sustained oscillations
KW  - biochemical oscillators
KW  - genetic networks
KW  - chemomechanical coupling
KW  - actin waves
Y1  - 2017
SN  - 978-0-8243-5008-6
U6  - https://doi.org/10.1146/annurev-conmatphys-031016-025210
SN  - 1947-5454
VL  - 8
SP  - 239
EP  - 264
PB  - Annual Reviews
CY  - Palo Alto
ER  - 
TY  - JOUR
A1  - Bezzenberger, Tilman
T1  - Coexistence and Harmonization of Company Laws
JF  - Developing Intra-regional Exchanges through the Abolition of Commercial and Tariff Barriers : Myth or Reality? (Cultures juridiques et politiques ; 10)
JF  - L’abolition des barrières commerciales et tarifaires dans la région de l’Océan indien : Mythe ou réalité? (Cultures juridiques et politiques ; 10)
Y1  - 2017
SN  - 978-2-8076-0126-0
U6  - https://doi.org/10.3726/978-2-8076-0127-7
SN  - 2235-1078
SP  - 181
EP  - 192
PB  - Lang
CY  - Bruxelles
ER  - 
TY  - JOUR
A1  - Bhat, Javaid Y.
A1  - Milicic, Goran
A1  - Thieulin-Pardo, Gabriel
A1  - Bracher, Andreas
A1  - Maxwell, Andrew
A1  - Ciniawsky, Susanne
A1  - Müller-Cajar, Oliver
A1  - Engen, John R.
A1  - Hartl, F. Ulrich
A1  - Wendler, Petra
A1  - Hayer-Hartl, Manajit
T1  - Mechanism of Enzyme Repair by the AAA(+) Chaperone Rubisco Activase
JF  - Molecular cell
N2  - How AAA(+) chaperones conformationally remodel specific target proteins in an ATP-dependent manner is not well understood. Here, we investigated the mechanism of the AAA(+) protein Rubisco activase (Rca) in metabolic repair of the photosynthetic enzyme Rubisco, a complex of eight large (RbcL) and eight small (RbcS) subunits containing eight catalytic sites. Rubisco is prone to inhibition by tight-binding sugar phosphates, whose removal is catalyzed by Rca. We engineered a stable Rca hexamer ring and analyzed its functional interaction with Rubisco. Hydrogen/deuterium exchange and chemical crosslinking showed that Rca structurally destabilizes elements of the Rubisco active site with remarkable selectivity. Cryo-electron microscopy revealed that Rca docks onto Rubisco over one active site at a time, positioning the C-terminal strand of RbcL, which stabilizes the catalytic center, for access to the Rca hexamer pore. The pulling force of Rca is fine-tuned to avoid global destabilization and allow for precise enzyme repair.
Y1  - 2017
U6  - https://doi.org/10.1016/j.molcel.2017.07.004
SN  - 1097-2765
SN  - 1097-4164
VL  - 67
SP  - 744
EP  - 756
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Bhuvanesh, Thanga
A1  - Saretia, Shivam
A1  - Roch, Toralf
A1  - Schöne, Anne-Christin
A1  - Rottke, Falko O.
A1  - Kratz, Karl
A1  - Wang, Weiwei
A1  - Ma, Nan
A1  - Schulz, Burkhard
A1  - Lendlein, Andreas
T1  - Langmuir-Schaefer films of fibronectin as designed biointerfaces for culturing stem cells
JF  - Polymers for advanced technologies
N2  - Glycoproteins adsorbing on an implant upon contact with body fluids can affect the biological response in vitro and in vivo, depending on the type and conformation of the adsorbed biomacromolecules. However, this process is poorly characterized and so far not controllable. Here, protein monolayers of high molecular cohesion with defined density are transferred onto polymeric substrates by the Langmuir-Schaefer (LS) technique and were compared with solution deposition (SO) method. It is hypothesized that on polydimethylsiloxane (PDMS), a substrate with poor cell adhesion capacity, the fibronectin (FN) layers generated by the LS and SO methods will differ in their organization, subsequently facilitating differential stem cell adhesion behavior. Indeed, atomic force microscopy visualization and immunofluorescence images indicated that organization of the FN layer immobilized on PDMS was uniform and homogeneous. In contrast, FN deposited by SO method was rather heterogeneous with appearance of structures resembling protein aggregates. Human mesenchymal stem cells showed reduced absolute numbers of adherent cells, and the vinculin expression seemed to be higher and more homogenously distributed after seeding on PDMS equipped with FN by LS in comparison with PDMS equipped with FN by SO. These divergent responses could be attributed to differences in the availability of adhesion molecule ligands such as the Arg-Gly-Asp (RGD) peptide sequence presented at the interface. The LS method allows to control the protein layer characteristics, including the thickness and the protein orientation or conformation, which can be harnessed to direct stem cell responses to defined outcomes, including migration and differentiation. Copyright (c) 2016 John Wiley & Sons, Ltd.
KW  - Langmuir-Schaefer method
KW  - protein adsorption
KW  - stem cell adhesion
KW  - cell culture
KW  - fibronectin
Y1  - 2017
U6  - https://doi.org/10.1002/pat.3910
SN  - 1042-7147
SN  - 1099-1581
VL  - 28
SP  - 1305
EP  - 1311
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Bisi-Balogun, Adebisi
A1  - Rector, Michael V.
T1  - Clinical Utility of Ultrasound Measurements of Plantar Fascia Width and Cross-Sectional Area
BT  - a novel technique
JF  - Journal of the American Podiatric Medical Association
N2  - Background: We sought to develop a standardized protocol for ultrasound (US) measurements of plantar fascia (PF) width and cross-sectional area (CSA), which may serve as additional outcome variables during US examinations of both healthy asymptomatic PF and in plantar fasciopathy and determine its interrater and intrarater reliability. Methods: Ten healthy individuals (20 feet) were enrolled. Participants were assessed twice by two raters each to determine intrarater and interrater reliability. For each foot, three transverse scans of the central bundle of the PF were taken at its insertion at the medial calcaneal tubercle, identified in real time on the plantar surface of the foot, using a fine wire technique. Reliability was determined using intraclass correlation coefficients (ICC), standard errors of measurement (SEM), and limits of agreement (LOA) expressed as percentages of the mean. Reliability of PF width and CSA measurements was determined using PF width and CSA measurements from one sonogram measured once and the mean of three measurements from three sonograms each measured once. Results: Ultrasound measurements of PF width and CSA showed a mean of 18.6 +/- 2.0 mm and 69.20 +/- 13.6 mm(2) respectively. Intra-reliability within both raters showed an ICC. 0.84 for width and ICC. 0.92 for CSA as well as a SEM% and LOA%, 10% for both width and CSA. Inter-rater reliability showed an ICC of 0.82 for width and 0.87 for CSA as well as a SEM% and LOA%, 10% for width and a SEM%, 10% and LOA%, 20% for CSA. Relative and absolute reliability within and between raters were higher when using the mean of three sonographs compared to one sonograph. Conclusions: Using this novel technique, PF CSA and width may be determined reliably using measurements from one sonogram or the mean of three sonograms. Measurement of PF CSA and width in addition to already established thickness and echogenicity measurements provides additional information on structural properties of the PF for clinicians and researchers in healthy and pathologic PF.
Y1  - 2017
U6  - https://doi.org/10.7547/16-042
SN  - 8750-7315
SN  - 1930-8264
VL  - 107
IS  - 5
SP  - 375
EP  - 381
PB  - Amer podiatric med assoc
CY  - Bethesda
ER  -