TY - JOUR A1 - Shaki, Samuel A1 - Fischer, Martin H. T1 - Your neighbors define your value a study of spatial bias in number comparison JF - Acta psychologica : international journal of psychonomics N2 - Several chronometric biases in numerical cognition have informed our understanding of a mental number line (MNL). Complementing this approach, we investigated spatial performance in a magnitude comparison task. Participants located the larger or smaller number of a pair on a horizontal line representing the interval from 0 to 10. Experiments 1 and 2 used only number pairs one unit apart and found that digits were localized farther to the right with "select larger" instructions than with "select smaller" instructions. However, when numerical distance was varied (Experiment 3), digits were localized away from numerically near neighbors. This repulsion effect reveals context-specific distortions in number representation not previously noticed with chronometric measures. KW - Magnitude comparison KW - Mental number line KW - Numerical cognition KW - Spatial bias Y1 - 2013 U6 - https://doi.org/10.1016/j.actpsy.2013.01.004 SN - 0001-6918 VL - 142 IS - 3 SP - 308 EP - 313 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Mirhaj, M. A1 - Boit, Alice A1 - Razzak, M. A. A1 - Wahab, M. A. T1 - Yield performance comparison between cultures of rice cum prawn (Macrobrachium rosenbergii) and rice cum fish (Cyprinus carpio, Oreochromis niloticus) in North-Eastern Bangladesh JF - Aquaculture : an international journal devoted to research on the exploration and improvement of all aquatic food resources, both floristic and faunistic, from freshwater, brackish and marine environment, related directly or indirectly to human consumption N2 - Integrated and concurrent cultures in rice fields are a promising approach to sustainable farming as the demand for aquacultural and agricultural products continues to grow while land and water resources become increasingly scarce. Prawn farming mainly takes place in coastal regions in improved extensive to semi-intensive aquacultures but a trend to shift the industry to inland regions has been noticed. This inland study in Northern Bangladesh used different input regimes such as fertilizer and additional feed to compare the performance of prawn and fish in flooded paddy fields in regard to water quality measurements. Maximal net yields and body weight gain with minimized negative impact on water quality were found when initial body weights of prawn were optimized. Regarding yield factors in reference to the reduction of costs due to the avoidance of expensive fertilizer/feed and effort, prawn performed better than integrated fish cultures considering a higher market value of prawn with net yields of up to 97 +/- 55 kg ha(-1) for unfed and 151 +/- 61 kg ha(-1) for fed treatments. Rice yields of up to 4.7 +/- 0.1 t ha(-1) for unfed and 4.4 +/- 0.1 t ha(-1) were achieved for fed treatments. The findings suggest that for small scale farmers, prawn cum rice cultures are an economically profitable and comparatively easily manageable alternative to rice cum fish cultures. KW - Rice cum prawn culture KW - Macrobrachium rosenbergii KW - Sustainable aquaculture KW - Polyculture Y1 - 2013 U6 - https://doi.org/10.1016/j.aquaculture.2013.01.038 SN - 0044-8486 VL - 392 IS - 5 SP - 26 EP - 33 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Burgemeister, S. A1 - Gvaramadze, Visily V. A1 - Stringfellow, G. S. A1 - Kniazev, Alexei Y. A1 - Todt, Helge Tobias A1 - Hamann, Wolf-Rainer T1 - WR 120bb and WR 120bc: a pair of WN9h stars with possibly interacting circumstellar shells JF - Monthly notices of the Royal Astronomical Society N2 - Two optically obscured Wolf-Rayet (WR) stars have been recently discovered by means of their infrared (IR) circumstellar shells, which show signatures of interaction with each other. Following the systematics of the WR star catalogues, these stars obtain the names WR 120bb and WR 120bc. In this paper, we present and analyse new near-IR, J-, H- and K-band spectra using the Potsdam Wolf-Rayet model atmosphere code. For that purpose, the atomic data base of the code has been extended in order to include all significant lines in the near-IR bands. The spectra of both stars are classified as WN9h. As their spectra are very similar the parameters that we obtained by the spectral analyses hardly differ. Despite their late spectral subtype, we found relatively high stellar temperatures of 63 kK. The wind composition is dominated by helium, while hydrogen is depleted to 25 per cent by mass. Because of their location in the Scutum-Centaurus Arm, WR 120bb and WR 120bc appear highly reddened, A(Ks) approximate to 2 mag. We adopt a common distance of 5.8 kpc to both stars, which complies with the typical absolute K-band magnitude for the WN9h subtype of -6.5 mag, is consistent with their observed extinction based on comparison with other massive stars in the region, and allows for the possibility that their shells are interacting with each other. This leads to luminosities of log(L/L-circle dot) = 5.66 and 5.54 for WR 120bb and WR 120bc, with large uncertainties due to the adopted distance. The values of the luminosities of WR 120bb and WR 120bc imply that the immediate precursors of both stars were red supergiants (RSG). This implies in turn that the circumstellar shells associated with WR 120bb and WR 120bc were formed by interaction between the WR wind and the dense material shed during the preceding RSG phase. KW - line: identification KW - circumstellar matter KW - stars: fundamental parameters KW - stars: massive KW - stars: Wolf-Rayet Y1 - 2013 U6 - https://doi.org/10.1093/mnras/sts588 SN - 0035-8711 SN - 1365-2966 VL - 429 IS - 4 SP - 3305 EP - 3315 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Klingstrom, Tomas A1 - Soldatova, Larissa A1 - Stevens, Robert A1 - Roos, T. Erik A1 - Swertz, Morris A. A1 - Müller, Kristian M. A1 - Kalas, Matus A1 - Lambrix, Patrick A1 - Taussig, Michael J. A1 - Litton, Jan-Eric A1 - Landegren, Ulf A1 - Bongcam-Rudloff, Erik T1 - Workshop on laboratory protocol standards for the molecular methods database JF - New biotechnology N2 - Management of data to produce scientific knowledge is a key challenge for biological research in the 21st century. Emerging high-throughput technologies allow life science researchers to produce big data at speeds and in amounts that were unthinkable just a few years ago. This places high demands on all aspects of the workflow: from data capture (including the experimental constraints of the experiment), analysis and preservation, to peer-reviewed publication of results. Failure to recognise the issues at each level can lead to serious conflicts and mistakes; research may then be compromised as a result of the publication of non-coherent protocols, or the misinterpretation of published data. In this report, we present the results from a workshop that was organised to create an ontological data-modelling framework for Laboratory Protocol Standards for the Molecular Methods Database (MolMeth). The workshop provided a set of short- and long-term goals for the MolMeth database, the most important being the decision to use the established EXACT description of biomedical ontologies as a starting point. Y1 - 2013 U6 - https://doi.org/10.1016/j.nbt.2012.05.019 SN - 1871-6784 VL - 30 IS - 2 SP - 109 EP - 113 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Rodriguez-Villagra, Odir Antonio A1 - Göthe, Katrin A1 - Oberauer, Klaus A1 - Kliegl, Reinhold T1 - Working memory capacity in a go/no-go task - age differences in interference, processing speed, and attentional control JF - Developmental psychology N2 - We tested the limits of working-memory capacity (WMC) of young adults, old adults, and children with a memory-updating task. The task consisted of mentally shifting spatial positions within a grid according to arrows, their color signaling either only go (control) or go/no-go conditions. The interference model (IM) of Oberauer and Kliegl (2006) was simultaneously fitted to the data of all groups. In addition to the 3 main model parameters (feature overlap, noise, and processing rate), we estimated the time for switching between go and no-go steps as a new model parameter. In this study, we examined the IM parameters across the life span. The IM parameter estimates show that (a) conditions were not different in interference by feature overlap and interference by confusion; (b) switching costs time; (c) young adults and children were less susceptible than old adults to interference due to feature overlap; (d) noise was highest for children, followed by old and young adults; (e) old adults differed from children and young adults in lower processing rate; and (f) children and old adults had a larger switch cost between go steps and no-go steps. Thus, the results of this study indicated that across age, the IM parameters contribute distinctively for explaining the limits of WMC. KW - working memory capacity KW - interference model KW - inhibition KW - children KW - old adults and young adults Y1 - 2013 U6 - https://doi.org/10.1037/a0030883 SN - 0012-1649 VL - 49 IS - 9 SP - 1683 EP - 1696 PB - American Psychological Association CY - Washington ER - TY - JOUR A1 - Rohrmann, Alexander A1 - Heermance, Richard A1 - Kapp, Paul A1 - Cai, Fulong T1 - Wind as the primary driver of erosion in the Qaidam Basin, China JF - Earth & planetary science letters N2 - Deserts are a major source of loess and may undergo substantial wind-erosion as evidenced by yardang fields, deflation pans, and wind-scoured bedrock landscapes. However, there are few quantitative estimates of bedrock removal by wind abrasion and deflation. Here, we report wind-erosion rates in the western Qaidam Basin in central China based on measurements of cosmogenic Be-10 in exhumed Miocene sedimentary bedrock. Sedimentary bedrock erosion rates range from 0.05 to 0.4 mm/yr, although the majority of measurements cluster at 0.125 +/- 0.05 mm/yr. These results, combined with previous work, indicate that strong winds, hyper-aridity, exposure of friable Neogene strata, and ongoing rock deformation and uplift in the western Qaidam Basin have created an environment where wind, instead of water, is the dominant agent of erosion and sediment transport. Its geographic location (upwind) combined with volumetric estimates suggest that the Qaidam Basin is a major source (up to 50%) of dust to the Chinese Loess Plateau to the east. The cosmogenically derived wind erosion rates are within the range of erosion rates determined from glacial and fluvial dominated landscapes worldwide, exemplifying the effectiveness of wind to erode and transport significant quantities of bedrock. KW - wind KW - cosmogenic nuclide-dating KW - earth surface processes KW - Chinese Loess Plateau KW - climate KW - Asia Y1 - 2013 U6 - https://doi.org/10.1016/j.epsl.2013.03.011 SN - 0012-821X VL - 374 SP - 1 EP - 10 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Tönnies, Sibylle T1 - Wider den westlichen Sonderweg : Globaler Melting Pot statt Clash of Civilizations Y1 - 2013 SN - 978-3-941880-71-9 ER - TY - JOUR A1 - Huebener, R. A1 - Mari, Andrea A1 - Eisert, Jens T1 - Wick's theorem for matrix product states JF - Physical review letters N2 - Matrix product states and their continuous analogues are variational classes of states that capture quantum many-body systems or quantum fields with low entanglement; they are at the basis of the density-matrix renormalization group method and continuous variants thereof. In this work we show that, generically, N-point functions of arbitrary operators in discrete and continuous translation invariant matrix product states are completely characterized by the corresponding two- and three-point functions. Aside from having important consequences for the structure of correlations in quantum states with low entanglement, this result provides a new way of reconstructing unknown states from correlation measurements, e. g., for one-dimensional continuous systems of cold atoms. We argue that such a relation of correlation functions may help in devising perturbative approaches to interacting theories. Y1 - 2013 U6 - https://doi.org/10.1103/PhysRevLett.110.040401 SN - 0031-9007 VL - 110 IS - 4 PB - American Physical Society CY - College Park ER - TY - BOOK A1 - Al-Saffar, Loay Talib Ahmed T1 - Where girls the role of boys in CS - attitudes of CS students in a female-dominated environment Y1 - 2013 SN - 978-3-86956-220-9 ER - TY - THES A1 - Knoll, Lisa Joanna T1 - When the hedgehog kisses the frog : a functional and structural investigatin of syntactic processing in the developing brain T2 - MPI series in human cognitive and brain sciences Y1 - 2013 SN - 978-3-941504-34-9 VL - 150 PB - MPI CY - Leipzig ER - TY - JOUR A1 - Vasishth, Shravan A1 - von der Malsburg, Titus Raban A1 - Engelmann, Felix T1 - What eye movements can tell us about sentence comprehension JF - Wiley interdisciplinary reviews : Cognitive Science N2 - Eye movement data have proven to be very useful for investigating human sentence processing. Eyetracking research has addressed a wide range of questions, such as recovery mechanisms following garden-pathing, the timing of processes driving comprehension, the role of anticipation and expectation in parsing, the role of semantic, pragmatic, and prosodic information, and so on. However, there are some limitations regarding the inferences that can be made on the basis of eye movements. One relates to the nontrivial interaction between parsing and the eye movement control system which complicates the interpretation of eye movement data. Detailed computational models that integrate parsing with eye movement control theories have the potential to unpack the complexity of eye movement data and can therefore aid in the interpretation of eye movements. Another limitation is the difficulty of capturing spatiotemporal patterns in eye movements using the traditional word-based eyetracking measures. Recent research has demonstrated the relevance of these patterns and has shown how they can be analyzed. In this review, we focus on reading, and present examples demonstrating how eye movement data reveal what events unfold when the parser runs into difficulty, and how the parsing system interacts with eye movement control. WIREs Cogn Sci 2013, 4:125134. doi: 10.1002/wcs.1209 For further resources related to this article, please visit the WIREs website. Y1 - 2013 U6 - https://doi.org/10.1002/wcs.1209 SN - 1939-5078 VL - 4 IS - 2 SP - 125 EP - 134 PB - Wiley CY - San Fransisco ER - TY - JOUR A1 - Vöth, Markus A1 - Herbst, Uta A1 - Liess, Frank T1 - We know exactly what you want the development of a completely individualised conjoint analysis JF - International journal of market research N2 - Improving the predictive validity of conjoint analysis has been an important research objective for many years. Whereas the majority of attempts have been different approaches to preference modelling, data collection or product presentation, only a few scholars have tried to improve predictive validity by individualising conjoint designs. This comes as a surprise because many markets have observed an augmented demand for customised products and highly heterogeneous customers' preferences. Against this background, the authors develop a conjoint variant based on a completely individualised conjoint design. More concretely, the new approach not only individualises the attributes, but also the attribute levels. The results of a comprehensive empirical study yield a significantly higher validity than existing standardised-level conjoint approaches. Consequently, they help marketers to gain deeper insights into their customers' preferences. Y1 - 2013 U6 - https://doi.org/10.2501/IJMR-2013-038 SN - 1470-7853 VL - 55 IS - 3 SP - 437 EP - 458 PB - Market Research Society CY - London ER - TY - JOUR A1 - Zaourar, N. A1 - Hamoudi, M. A1 - Mandea, M. A1 - Balasis, G. A1 - Holschneider, Matthias T1 - Wavelet-based multiscale analysis of geomagnetic disturbance JF - EARTH PLANETS AND SPACE N2 - The dynamics of external contributions to the geomagnetic field is investigated by applying time-frequency methods to magnetic observatory data. Fractal models and multiscale analysis enable obtaining maximum quantitative information related to the short-term dynamics of the geomagnetic field activity. The stochastic properties of the horizontal component of the transient external field are determined by searching for scaling laws in the power spectra. The spectrum fits a power law with a scaling exponent beta, a typical characteristic of self-affine time-series. Local variations in the power-law exponent are investigated by applying wavelet analysis to the same time-series. These analyses highlight the self-affine properties of geomagnetic perturbations and their persistence. Moreover, they show that the main phases of sudden storm disturbances are uniquely characterized by a scaling exponent varying between 1 and 3, possibly related to the energy contained in the external field. These new findings suggest the existence of a long-range dependence, the scaling exponent being an efficient indicator of geomagnetic activity and singularity detection. These results show that by using magnetogram regularity to reflect the magnetosphere activity, a theoretical analysis of the external geomagnetic field based on local power-law exponents is possible. KW - Geomagnetic field KW - magnetosphere KW - geomagnetic storm KW - multiscale analysis KW - spectral exponent Y1 - 2013 U6 - https://doi.org/10.5047/eps.2013.05.001 SN - 1343-8832 SN - 1880-5981 VL - 65 IS - 12 SP - 1525 EP - 1540 PB - TERRA SCIENTIFIC PUBL CO CY - TOKYO ER - TY - JOUR A1 - Neill, Christopher A1 - Coe, Michael T. A1 - Riskin, Shelby H. A1 - Krusche, Alex V. A1 - Elsenbeer, Helmut A1 - Macedo, Marcia N. A1 - McHorney, Richard A1 - Lefebvre, Paul A1 - Davidson, Eric A. A1 - Scheffler, Raphael A1 - Figueira, Adelaine Michela e Silva A1 - Porder, Stephen A1 - Deegan, Linda A. T1 - Watershed responses to Amazon soya bean cropland expansion and intensification JF - Philosophical transactions of the Royal Society of London : B, Biological sciences N2 - The expansion and intensification of soya bean agriculture in southeastern Amazonia can alter watershed hydrology and biogeochemistry by changing the land cover, water balance and nutrient inputs. Several new insights on the responses of watershed hydrology and biogeochemistry to deforestation in Mato Grosso have emerged from recent intensive field campaigns in this region. Because of reduced evapotranspiration, total water export increases threefold to fourfold in soya bean watersheds compared with forest. However, the deep and highly permeable soils on the broad plateaus on which much of the soya bean cultivation has expanded buffer small soya bean watersheds against increased stormflows. Concentrations of nitrate and phosphate do not differ between forest or soya bean watersheds because fixation of phosphorus fertilizer by iron and aluminium oxides and anion exchange of nitrate in deep soils restrict nutrient movement. Despite resistance to biogeochemical change, streams in soya bean watersheds have higher temperatures caused by impoundments and reduction of bordering riparian forest. In larger rivers, increased water flow, current velocities and sediment flux following deforestation can reshape stream morphology, suggesting that cumulative impacts of deforestation in small watersheds will occur at larger scales. KW - soya beans KW - watersheds KW - nitrogen KW - phosphorus KW - soil Y1 - 2013 U6 - https://doi.org/10.1098/rstb.2012.0425 SN - 0962-8436 SN - 1471-2970 VL - 368 IS - 1619 PB - Royal Society CY - London ER - TY - JOUR A1 - Vock, Miriam A1 - Köller, Olaf A1 - Nagy, Gabriel T1 - Vocational interests of intellectually gifted and highly achieving young adults JF - British journal of educational psychology N2 - Background.Vocational interests play a central role in the vocational decision-making process and are decisive for the later job satisfaction and vocational success. Based on Ackerman's (1996) notion of trait complexes, specific interest profiles of gifted high-school graduates can be expected. Aims.Vocational interests of gifted and highly achieving adolescents were compared to those of their less intelligent/achieving peers according to Holland's (1997) RIASEC model. Further, the impact of intelligence and achievement on interests were analysed while statistically controlling for potentially influencing variables. Changes in interests over time were investigated. Sample.N= 4,694 German students (age: M= 19.5, SD= .80; 54.6% females) participated in the study (TOSCA; Koller, Watermann, Trautwein, & Ludtke, 2004). Method. Interests were assessed in participants' final year at school and again 2 years later (N= 2,318). Results.Gifted participants reported stronger investigative and realistic interests, but lower social interests than less intelligent participants. Highly achieving participants reported higher investigative and (in wave 2) higher artistic interests. Considerable gender differences were found: gifted girls had a flat interest profile, while gifted boys had pronounced realistic and investigative and low social interests. Multilevel multiple regression analyses predicting interests by intelligence and school achievement revealed stable interest profiles. Beyond a strong gender effect, intelligence and school achievement each contributed substantially to the prediction of vocational interests. Conclusions.At the time around graduation from high school, gifted young adults show stable interest profiles, which strongly differ between gender and intelligence groups. These differences are relevant for programmes for the gifted and for vocational counselling. Y1 - 2013 U6 - https://doi.org/10.1111/j.2044-8279.2011.02063.x SN - 0007-0998 VL - 83 IS - 2 SP - 305 EP - 328 PB - Wiley-Blackwell CY - Hoboken ER - TY - INPR A1 - Hocher, Berthold A1 - Reichetzeder, Christoph T1 - Vitamin D and cardiovascular risk in postmenopausal women how to translate preclinical evidence into benefit for patients T2 - Kidney international : official journal of the International Society of Nephrology N2 - Preclinical work indicates that calcitriol restores vascular function by normalizing the endothelial expression of cyclooxygenase-2 and thromboxane-prostanoid receptors in conditions of estrogen deficiency and thus prevents the thromboxane-prostanoid receptor activation-induced inhibition of nitric oxide synthase. Since endothelial dysfunction is a key factor in the pathogenesis of cardiovascular diseases, this finding may have an important translational impact. It provides a clear rationale to use endothelial function in clinical trials aiming to find the optimal dose of vitamin D for the prevention of cardiovascular events in postmenopausal women. Y1 - 2013 U6 - https://doi.org/10.1038/ki.2013.139 SN - 0085-2538 VL - 84 IS - 1 SP - 9 EP - 11 PB - Nature Publ. Group CY - New York ER - TY - JOUR A1 - Myachykov, Andriy A1 - Ellis, Rob A1 - Cangelosi, Angelo A1 - Fischer, Martin H. T1 - Visual and linguistic cues to graspable objects JF - Experimental brain research N2 - Two experiments investigated (1) how activation of manual affordances is triggered by visual and linguistic cues to manipulable objects and (2) whether graspable object parts play a special role in this process. Participants pressed a key to categorize manipulable target objects copresented with manipulable distractor objects on a computer screen. Three factors were varied in Experiment 1: (1) the target's and (2) the distractor's handles' orientation congruency with the lateral manual response and (3) the Visual Focus on one of the objects. In Experiment 2, a linguistic cue factor was added to these three factors-participants heard the name of one of the two objects prior to the target display onset. Analysis of participants' motor and oculomotor behaviour confirmed that perceptual and linguistic cues potentiated activation of grasp affordances. Both target- and distractor-related affordance effects were modulated by the presence of visual and linguistic cues. However, a differential visual attention mechanism subserved activation of compatibility effects associated with target and distractor objects. We also registered an independent implicit attention attraction effect from objects' handles, suggesting that graspable parts automatically attract attention during object viewing. This effect was further amplified by visual but not linguistic cues, thus providing initial evidence for a recent hypothesis about differential roles of visual and linguistic information in potentiating stable and variable affordances (Borghi in Language and action in cognitive neuroscience. Psychology Press, London, 2012). KW - Grasp affordances KW - Naming KW - Visual attention KW - Object categorization Y1 - 2013 U6 - https://doi.org/10.1007/s00221-013-3616-z SN - 0014-4819 VL - 229 IS - 4 SP - 545 EP - 559 PB - Springer CY - New York ER - TY - JOUR A1 - Rolfs, Martin A1 - Dambacher, Michael A1 - Cavanagh, Patrick T1 - Visual adaptation of the perception of causality JF - Current biology N2 - We easily recover the causal properties of visual events, enabling us to understand and predict changes in the physical world. We see a tennis racket hitting a ball and sense that it caused the ball to fly over the net; we may also have an eerie but equally compelling experience of causality if the streetlights turn on just as we slam our car's door. Both perceptual [1] and cognitive [2] processes have been proposed to explain these spontaneous inferences, but without decisive evidence one way or the other, the question remains wide open [3-8]. Here, we address this long-standing debate using visual adaptation-a powerful tool to uncover neural populations that specialize in the analysis of specific visual features [9-12]. After prolonged viewing of causal collision events called "launches" [1], subsequently viewed events were judged more often as noncausal. These negative aftereffects of exposure to collisions are spatially localized in retinotopic coordinates, the reference frame shared by the retina and visual cortex. They are not explained by adaptation to other stimulus features and reveal visual routines in retinotopic cortex that detect and adapt to cause and effect in simple collision stimuli. Y1 - 2013 U6 - https://doi.org/10.1016/j.cub.2012.12.017 SN - 0960-9822 VL - 23 IS - 3 SP - 250 EP - 254 PB - Cell Press CY - Cambridge ER - TY - INPR A1 - Caligiore, Daniele A1 - Fischer, Martin H. T1 - Vision, action and language unified through embodiment T2 - Psychological research : an international journal of perception, attention, memory, and action Y1 - 2013 U6 - https://doi.org/10.1007/s00426-012-0417-0 SN - 0340-0727 VL - 77 IS - 1 SP - 1 EP - 6 PB - Springer CY - Heidelberg ER - TY - THES A1 - Hoffmann, Holger T1 - Vertical structures induced by embedded propeller moonlets in Saturn's rings Y1 - 2013 CY - Potsdam ER - TY - JOUR A1 - Hoffmann, H. A1 - Seiß, Martin A1 - Spahn, Frank T1 - Vertical relaxation of a moonlet propeller in Saturn's a ring JF - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters N2 - Two images, taken by the Cassini spacecraft near Saturn's equinox in 2009 August, show the Earhart propeller casting a 350 km long shadow, offering the opportunity to watch how the ring height, excited by the propeller moonlet, relaxes to an equilibrium state. From the shape of the shadow cast and a model of the azimuthal propeller height relaxation, we determine the exponential cooling constant of this process to be lambda = 0.07 +/- 0.02 km(-1), and thereby determine the collision frequency of the ring particles in the vertically excited region of the propeller to be omega(c)/Omega = 0.9 +/- 0.2. KW - planets and satellites: individual (Saturn) KW - planets and satellites: rings Y1 - 2013 U6 - https://doi.org/10.1088/2041-8205/765/1/L4 SN - 2041-8205 VL - 765 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Archambault, S. A1 - Beilicke, M. A1 - Benbow, W. A1 - Berger, K. A1 - Bird, R. A1 - Bouvier, A. A1 - Buckley, J. H. A1 - Bugaev, V. A1 - Byrum, K. A1 - Cerruti, M. A1 - Chen, Xuhui A1 - Ciupik, L. A1 - Connolly, M. P. A1 - Cui, W. A1 - Duke, C. A1 - Dumm, J. A1 - Errando, M. A1 - Falcone, A. A1 - Federici, Simone A1 - Feng, Q. A1 - Finley, J. P. A1 - Fortson, L. A1 - Furniss, A. A1 - Galante, N. A1 - Gillanders, G. H. A1 - Griffin, S. A1 - Griffiths, S. T. A1 - Grube, J. A1 - Gyuk, G. A1 - Hanna, D. A1 - Holder, J. A1 - Hughes, G. A1 - Humensky, T. B. A1 - Kaaret, P. A1 - Kertzman, M. A1 - Khassen, Y. A1 - Kieda, D. A1 - Krawczynski, H. A1 - Lang, M. J. A1 - Madhavan, A. S. A1 - Maier, G. A1 - Majumdar, P. A1 - McArthur, S. A1 - McCann, A. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Nieto, D. A1 - de Bhroithe, A. O'Faolain A1 - Ong, R. A. A1 - Otte, A. N. A1 - Pandel, D. A1 - Park, N. A1 - Perkins, J. S. A1 - Pohl, Martin A1 - Popkow, A. A1 - Prokoph, H. A1 - Quinn, J. A1 - Ragan, K. A1 - Rajotte, J. A1 - Reyes, L. C. A1 - Reynolds, P. T. A1 - Richards, G. T. A1 - Roache, E. A1 - Sembroski, G. H. A1 - Sheidaei, F. A1 - Smith, A. W. A1 - Staszak, D. A1 - Telezhinsky, Igor O. A1 - Theiling, M. A1 - Tucci, J. V. A1 - Tyler, J. A1 - Varlotta, A. A1 - Vincent, S. A1 - Wakely, S. P. A1 - Weekes, T. C. A1 - Weinstein, A. A1 - Williams, D. A. A1 - Zitzer, B. A1 - McCollough, M. L. T1 - Veritas observatons of the microquasar cygnus X-3 JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We report results from TeV gamma-ray observations of the microquasar Cygnus X-3. The observations were made with the Very Energetic Radiation Imaging Telescope Array System (VERITAS) over a time period from 2007 June 11 to 2011 November 28. VERITAS is most sensitive to gamma rays at energies between 85 GeV and 30 TeV. The effective exposure time amounts to a total of about 44 hr, with the observations covering six distinct radio/X-ray states of the object. No significant TeV gamma-ray emission was detected in any of the states, nor with all observations combined. The lack of a positive signal, especially in the states where GeV gamma rays were detected, places constraints on TeV gamma-ray production in Cygnus X-3. We discuss the implications of the results. KW - acceleration of particles KW - binaries: close KW - gamma rays: stars KW - X-rays: individual (Cygnus X-3) Y1 - 2013 U6 - https://doi.org/10.1088/0004-637X/779/2/150 SN - 0004-637X SN - 1538-4357 VL - 779 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Cheng, Lisa Lai-Shen A1 - Vicente, Luis T1 - Verb doubling in Mandarin Chinese JF - Journal of East Asian linguistics N2 - This article examines two so-far-understudied verb doubling constructions in Mandarin Chinese, viz., verb doubling clefts and verb doubling lianaEuro broken vertical bar dou. We show that these constructions have the same internal syntax as regular clefts and lianaEuro broken vertical bar dou sentences, the doubling effect being epiphenomenal; therefore, we classify them as subtypes of the general cleft and lianaEuro broken vertical bar dou constructions, respectively, rather than as independent constructions. Additionally, we also show that, as in many other languages with comparable constructions, the two instances of the verb are part of a single movement chain, which has the peculiarity of allowing Spell-Out of more than one link. KW - Mandarin Chinese KW - Verb doubling KW - Verb movement KW - Cleft KW - lian ... dou Y1 - 2013 U6 - https://doi.org/10.1007/s10831-012-9095-6 SN - 0925-8558 VL - 22 IS - 1 SP - 1 EP - 37 PB - Springer CY - Dordrecht ER - TY - THES A1 - Czech, Andreas T1 - Variations in the tRNA pool of mammalian cells upon differentiation and oxidative stress Y1 - 2013 CY - Potsdam ER - TY - JOUR A1 - Scheffler, Christiane T1 - Variable and Invariable Proportions in the Ontogenesis of the Human Face Y1 - 2013 ER - TY - JOUR A1 - Scheffler, Christiane T1 - Variable and invariable proportions in the ontogenesis of the human face JF - The journal of craniofacial surgery : an international journal dedicated to the practice of the art and science of craniofacial surgery ; official publication of the American Association of Pediatric Plastic Surgeons N2 - The human face shows individual features and features that are characteristic for sex and age (the loss of childlike characteristics during maturation). The analysis of facial dimensions is essential for identifying individual features also for forensic issues. The analysis of facial proportions was performed on photogrammetric data from front views of 125 children. The data were pooled from 2 different studies. The children's data were obtained from a longitudinal study and reduced by random generator to ensure the data of adults from a separate cross-sectional study. We applied principal component analysis on photogrammetric facial proportions of 169 individuals: 125 children (63 boys and 62 girls) aged 2-7 years and 44 adults (18 men and 26 women) aged 18-65 years. Facial proportions depend on age and sex. Three components described age: (1) proportions of facial height to head height, (2) proportions that involve endocanthal breadth, and (3) bigonial to bizygonial proportions. Proportions that associate with sex are connected with nasal distances and nasal to bizygonial distances. Twenty-three percent of the variance, particularly variance that are connected with proportions of lower and middle face heights to head height, do neither depend on sex nor on age and thus appear useful for screening purposes, eg, for dysmorphic genetic syndromes. KW - Human face KW - face proportions KW - ontogenesis KW - principal component analysis Y1 - 2013 U6 - https://doi.org/10.1097/SCS.0b013e31826d07a3 SN - 1049-2275 VL - 24 IS - 1 SP - 237 EP - 241 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Lamprecht, Anna-Lena A1 - Naujokat, Stefan A1 - Schaefer, Ina T1 - Variability Management beyond Feature Models JF - COMPUTER N2 - When new customer and regulatory requirements arise, the ability to quickly adapt business information system processes is crucial to stay ahead of competitors. A proposed synthesis-based framework enables the development of business processes that automatically yield fully executable variants. Y1 - 2013 SN - 0018-9162 SN - 1558-0814 VL - 46 IS - 11 SP - 48 EP - 54 PB - IEEE COMPUTER SOC CY - LOS ALAMITOS ER - TY - THES A1 - Schleussner, Carl-Friedrich T1 - Variability and trend of the North Atlantic ocean circulation in past and future climate Y1 - 2013 CY - Potsdam ER - TY - JOUR A1 - Lange, Bastian A1 - Bürkner, Hans-Joachim T1 - Value creation in scene-based music production - the case of electronic club music in Germany JF - Economic geography N2 - The focus of this article is on the variability of value creation in the popular music industry. Recent trends in electronic music have been based on both the valorization of global tastes and of local specialities in performance and production. Depending on musical styles and market niches, local scenes have become important forces behind heterogeneous globalocal markets. At the same time, technological change and the virtualization of music production and distribution contribute to increasingly differentiated configurations of value creation. It is therefore necessary to reconstruct theoretically and empirically the new interplay among the local music production, digital media markets, and virtual communities that are involved. On the basis of empirical explorations in a German hot spot of electronic club-music production (the city of Berlin), the article indentifies local interaction practice and constellations of stakeholders. The findings show that value creation in these rapidly changing production scenes has moved away from the large-scale distribution of producer-induced media to audience-induced live performance and interactive soundtrack production. This change involves the rising importance of cultural embeddings such as taste building, reputation building among artists and producers, and local community building. Starting from an open theoretical problematization of value creation with regard to fluid scenes and shifting modes of production, the results of first empirical reconstructions are taken as inputs to an evolving discussion on the configurations of value creation in consumer-based strands of music production. KW - music industry KW - value creation KW - value chain KW - creative economy KW - Berlin Y1 - 2013 U6 - https://doi.org/10.1111/ecge.12002 SN - 0013-0095 VL - 89 IS - 2 SP - 149 EP - 169 PB - Wiley-Blackwell CY - Hoboken ER - TY - CHAP A1 - Engel, Tilman A1 - Müller, Juliane A1 - Müller, Steffen A1 - Reschke, Antje A1 - Kopinski, Stephan A1 - Mayer, Frank T1 - Validity and reliability of a new customised split-belt treadmill provoking unexpected walking perturbations T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2013 SN - 0195-9131 SN - 1530-0315 VL - 45 IS - 5 SP - 462 EP - 462 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Heistermann, Maik A1 - Crisologo, Irene A1 - Abon, Catherine Cristobal A1 - Racoma, B. A. A1 - Jacobi, S. A1 - Servando, N. T. A1 - David, C. P. C. A1 - Bronstert, Axel T1 - Using the new Philippine radar network to reconstruct the Habagat of August 2012 monsoon event around Metropolitan Manila JF - Natural hazards and earth system sciences N2 - From 6 to 9 August 2012, intense rainfall hit the northern Philippines, causing massive floods in Metropolitan Manila and nearby regions. Local rain gauges recorded almost 1000mm within this period. However, the recently installed Philippine network of weather radars suggests that Metropolitan Manila might have escaped a potentially bigger flood just by a whisker, since the centre of mass of accumulated rainfall was located over Manila Bay. A shift of this centre by no more than 20 km could have resulted in a flood disaster far worse than what occurred during Typhoon Ketsana in September 2009. Y1 - 2013 U6 - https://doi.org/10.5194/nhess-13-653-2013 SN - 1561-8633 VL - 13 IS - 3 SP - 653 EP - 657 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Neumann-Schaal, Meina A1 - Messerschmidt, Katrin A1 - Grenz, Nicole A1 - Heilmann, Katja T1 - Use of antibody gene library for the isolation of specific single chain antibodies. by ampicillin-antigen conjugates JF - Immunology letters : an international journal providing for the rapid publication of short reports in immunology N2 - Isolation of recombinant antibodies from antibody libraries is commonly performed by different molecular display formats including phage display and ribosome display or different cell-surface display formats. We describe a new method which allows the selection of Escherichia coil cells producing the required single chain antibody by cultivation in presence of ampicillin conjugated to the antigen of interest. The method utilizes the neutralization of the conjugate by the produced single chain antibody which is secreted to the periplasm. Therefore, a new expression system based on the pET26b vector was designed and a library was constructed. The method was successfully established first for the selection of E. coli BL21 Star (DE3) cells expressing a model single chain antibody (anti-fluorescein) by a simple selection assay on LB-agar plates. Using this selection assay, we could identify a new single chain antibody binding biotin by growing E. coil BL21 Star (DE3) containing the library in presence of a biotin-ampicillin conjugate. In contrast to methods as molecular or cell surface display our selection system applies the soluble single chain antibody molecule and thereby avoids undesired effects, e.g. by the phage particle or the yeast fusion protein. By selecting directly in an expression strain, production and characterization of the selected single chain antibody is possible without any further cloning or transformation steps. KW - Single chain antibody KW - Selection method KW - Anti-biotin antibody KW - Naive single chain library Y1 - 2013 U6 - https://doi.org/10.1016/j.imlet.2013.02.005 SN - 0165-2478 VL - 151 IS - 1-2 SP - 39 EP - 43 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Messerschmidt, Katrin A1 - Neumann-Schaal, Meina A1 - Heilmann, Katja T1 - Use of antibody gene library for the isolation of specific single chain antibodies by ampicillinantigen conjugates T2 - The journal of immunology Y1 - 2013 SN - 0022-1767 VL - 190 PB - American Assoc. of Immunologists CY - Bethesda ER - TY - THES A1 - Mühlenbruch, Kristin T1 - Updating the german diabetes risk score - model extensions, validation and reclassification Y1 - 2013 CY - Potsdam ER - TY - JOUR A1 - Boch, Steffen A1 - Müller, Jörg A1 - Pratil, Daniel A1 - Blaser, Stefan A1 - Fischer, Markus T1 - Up in the tree - the overlooked richness of bryophytes and lichens in Tree Crowns JF - PLoS one N2 - Assessing diversity is among the major tasks in ecology and conservation science. In ecological and conservation studies, epiphytic cryptogams are usually sampled up to accessible heights in forests. Thus, their diversity, especially of canopy specialists, likely is underestimated. If the proportion of those species differs among forest types, plot-based diversity assessments are biased and may result in misleading conservation recommendations. We sampled bryophytes and lichens in 30 forest plots of 20 m x 20 m in three German regions, considering all substrates, and including epiphytic litter fall. First, the sampling of epiphytic species was restricted to the lower 2 m of trees and shrubs. Then, on one representative tree per plot, we additionally recorded epiphytic species in the crown, using tree climbing techniques. Per tree, on average 54% of lichen and 20% of bryophyte species were overlooked if the crown was not been included. After sampling all substrates per plot, including the bark of all shrubs and trees, still 38% of the lichen and 4% of the bryophyte species were overlooked if the tree crown of the sampled tree was not included. The number of overlooked lichen species varied strongly among regions. Furthermore, the number of overlooked bryophyte and lichen species per plot was higher in European beech than in coniferous stands and increased with increasing diameter at breast height of the sampled tree. Thus, our results indicate a bias of comparative studies which might have led to misleading conservation recommendations of plot-based diversity assessments. Y1 - 2013 U6 - https://doi.org/10.1371/journal.pone.0084913 SN - 1932-6203 VL - 8 IS - 12 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Eichmair, Michael A1 - Metzger, Jan T1 - Unique isoperimetric foliations of asymptotically flat manifolds in all dimensions JF - Inventiones mathematicae Y1 - 2013 U6 - https://doi.org/10.1007/s00222-013-0452-5 SN - 0020-9910 SN - 1432-1297 VL - 194 IS - 3 SP - 591 EP - 630 PB - Springer CY - New York ER - TY - JOUR A1 - Szatmari, Istvan A1 - Heydenreich, Matthias A1 - Koch, Andreas A1 - Fulop, Ferenc A1 - Kleinpeter, Erich T1 - Unexpected isomerization of new naphth[1,3]oxazino[2,3-a] isoquinolines in solution, studied by dynamic NMR and supported by theoretical DFT computations JF - Tetrahedron N2 - Through the reactions of 1-aminomethyl-2-naphthol and substituted 1-aminobenzyl-2-naphthols with 3,4-dihydroisoquinoline or 6,7-dimethoxy-3,4-dihydroisoquinoline under microwave conditions, naphth[1,2-e][1,3]oxazino[2,3-a]-isoquinoline derivatives were prepared in good yields. The latter reaction was extended by using 2-aminoarylmethyl-1-naphthols, leading to isomeric naphth-[2,1-e][1,3]oxazino[2,3-a] isoquinolines. Beside the detailed NMR spectroscopic and theoretical study of both stereochemistry and dynamic behaviour of these new conformational flexible heterocyclic ring systems an unexpected dynamic process between two diastereomers was observed in solution, studied by variable temperature H-1 NMR spectroscopy and the mechanism proved by theoretical DFT computations. KW - 3,4-Dihydroisoquinoline KW - Aminonaphthol KW - Dynamic NMR spectroscopy KW - DFT calculations KW - Conformational analysis Y1 - 2013 U6 - https://doi.org/10.1016/j.tet.2013.06.094 SN - 0040-4020 VL - 69 IS - 35 SP - 7455 EP - 7465 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Pohl, Martin A1 - Eichler, David T1 - Understanding TeV-band cosmic-ray anistropy JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We investigate the temporal and spectral correlations between flux and anisotropy fluctuations of TeV-band cosmic rays in light of recent data taken with IceCube. We find that for a conventional distribution of cosmic-ray sources, the dipole anisotropy is higher than observed, even if source discreteness is taken into account. Moreover, even for a shallow distribution of galactic cosmic-ray sources and a reacceleration model, fluctuations arising from source discreteness provide a probability only of the order of 10% that the cosmic-ray anisotropy limits of the recent IceCube analysis are met. This probability estimate is nearly independent of the exact choice of source rate, but generous for a large halo size. The location of the intensity maximum far from the Galactic Center is naturally reproduced. KW - cosmic rays Y1 - 2013 U6 - https://doi.org/10.1088/0004-637X/766/1/4 SN - 0004-637X VL - 766 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - THES A1 - Albrecht, Alexander T1 - Understanding and managing extract-transform-load systems Y1 - 2013 ER - TY - JOUR A1 - Beck, Jan A1 - Holloway, Jeremy D. A1 - Schwanghart, Wolfgang T1 - Undersampling and the measurement of beta diversity JF - Methods in ecology and evolution : an official journal of the British Ecological Society N2 - Beta diversity is a conceptual link between diversity at local and regional scales. Various additional methodologies of quantifying this and related phenomena have been applied. Among them, measures of pairwise (dis)similarity of sites are particularly popular. Undersampling, i.e. not recording all taxa present at a site, is a common situation in ecological data. Bias in many metrics related to beta diversity must be expected, but only few studies have explicitly investigated the properties of various measures under undersampling conditions. On the basis of an empirical data set, representing near-complete local inventories of the Lepidoptera from an isolated Pacific island, as well as simulated communities with varying properties, we mimicked different levels of undersampling. We used 14 different approaches to quantify beta diversity, among them dataset-wide multiplicative partitioning (i.e. true beta diversity') and pairwise site x site dissimilarities. We compared their values from incomplete samples to true results from the full data. We used these comparisons to quantify undersampling bias and we calculated correlations of the dissimilarity measures of undersampled data with complete data of sites. Almost all tested metrics showed bias and low correlations under moderate to severe undersampling conditions (as well as deteriorating precision, i.e. large chance effects on results). Measures that used only species incidence were very sensitive to undersampling, while abundance-based metrics with high dependency on the distribution of the most common taxa were particularly robust. Simulated data showed sensitivity of results to the abundance distribution, confirming that data sets of high evenness and/or the application of metrics that are strongly affected by rare species are particularly sensitive to undersampling. The class of beta measure to be used should depend on the research question being asked as different metrics can lead to quite different conclusions even without undersampling effects. For each class of metric, there is a trade-off between robustness to undersampling and sensitivity to rare species. In consequence, using incidence-based metrics carries a particular risk of false conclusions when undersampled data are involved. Developing bias corrections for such metrics would be desirable. KW - Bray-Curtis KW - Chao KW - Effective number of species KW - Incomplete inventories KW - Jaccard KW - Macrolepidoptera KW - Morisita KW - Morisita-Horn KW - NESS KW - Norfolk Island Y1 - 2013 U6 - https://doi.org/10.1111/2041-210x.12023 SN - 2041-210X VL - 4 IS - 4 SP - 370 EP - 382 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Wiemann, Dirk T1 - Undead or immortal? : red army faction afterlives Y1 - 2013 SN - 978-3-361-60196-9 ER - TY - JOUR A1 - Zimmermann, Alexander A1 - Schinn, Dustin S. A1 - Francke, Till A1 - Elsenbeer, Helmut A1 - Zimmermann, Beate T1 - Uncovering patterns of near-surface saturated hydraulic conductivity in an overland flow-controlled landscape JF - Geoderma : an international journal of soil science N2 - Saturated hydraulic conductivity (K-s) is an important soil characteristic affecting soil water storage, runoff generation and erosion processes. In some areas where high-intensity rainfall coincides with low K-s values at shallow soil depths, frequent overland flow entails dense drainage networks. Consequently, linear structures such as flowlines alternate with inter-flowline areas. So far, investigations of the spatial variability of K-s mainly relied on isotropic covariance models which are unsuitable to reveal patterns resulting from linear structures. In the present study, we applied two sampling approaches so as to adequately characterize K-s spatial variability in a tropical forest catchment that features a high density of flowlines: A classical nested sampling survey and a purposive sampling strategy adapted to the presence of flowlines. The nested sampling approach revealed the dominance of small-scale variability, which is in line with previous findings. Our purposive sampling, however, detected a strong spatial gradient: surface K-s increased substantially as a function of distance to flowline; 10 m off flowlines, values were similar to the spatial mean of K-s. This deterministic trend can be included as a fixed effect in a linear mixed modeling framework to obtain realistic spatial fields of K-s. In a next step we used probability maps based on those fields and prevailing rainfall intensities to assess the hydrological relevance of the detected pattern. This approach suggests a particularly good agreement between the probability statements of K-s exceedance and observed overland flow occurrence during wet stages of the rainy season. KW - Soil hydrology KW - Saturated hydraulic conductivity KW - Overland flow generation KW - Spatial patterns KW - Drainage network Y1 - 2013 U6 - https://doi.org/10.1016/j.geoderma.2012.11.002 SN - 0016-7061 VL - 195 IS - 169 SP - 1 EP - 11 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hammes, Ursula A1 - Krause, Michael A1 - Mutti, Maria T1 - Unconventional reservoir potential of the upper Permian Zechstein Group - a slope to basin sequence stratigraphic and sedimentological evaluation of carbonates and organic-rich mudrocks, Northern Germany JF - Environmental earth sciences N2 - The Late Permian Zechstein Group in northeastern Germany is characterized by shelf and slope carbonates that rimmed a basin extending from eastern England through the Netherlands and Germany to Poland. Conventional reservoirs are found in grainstones rimming islands created by pre-existing paleohighs and platform-rimming shoals that compose steep margins in the north and ramp deposits in the southern part. The slope and basin deposits are characterized by debris flows and organic-rich mudstones. Lagoonal and basinal evaporites formed the seal for these carbonate and underlying sandstone reservoirs. The objective of this investigation is to evaluate potential unconventional reservoirs in organic-rich, fine-grained and/or tight mudrocks in slope and basin as well as platform carbonates occurring in this stratigraphic interval. Therefore, a comprehensive study was conducted that included sedimentology, sequence stratigraphy, petrography, and geochemistry. Sequence stratigraphic correlations from shelf to basin are crucial in establishing a framework that allows correlation of potential productive facies in fine-grained, organic-rich basinal siliceous and calcareous mudstones or interfingering tight carbonates and siltstones, ranging from the lagoon, to slope to basin, which might be candidates for forming an unconventional reservoir. Most organic-rich shales worldwide are associated with eustatic transgressions. The basal Zechstein cycles, Z1 and Z2, contain organic-rich siliceous and calcareous mudstones and carbonates that form major transgressive deposits in the basin. Maturities range from over-mature (gas) in the basin to oil-generation on the slope with variable TOC contents. This sequence stratigraphic and sedimentologic evaluation of the transgressive facies in the Z1 and Z2 assesses the potential for shale-gas/oil and hybrid unconventional plays. Potential unconventional reservoirs might be explored in laminated organic-rich mudstones within the oil window along the northern and southern slopes of the basin. Although the Zechstein Z1 and Z2 cycles might have limited shale-gas potential because of low thickness and deep burial depth to be economic at this point, unconventional reservoir opportunities that include hybrid and shale-oil potential are possible in the study area. KW - Upper Permian Zechstein Group Northern Germany KW - Unconventional reservoir potential KW - Mudrock analyses KW - Sequence stratigraphy KW - Carbonate and mudrock facies Y1 - 2013 U6 - https://doi.org/10.1007/s12665-013-2724-1 SN - 1866-6280 SN - 1866-6299 VL - 70 IS - 8 SP - 3797 EP - 3816 PB - Springer CY - New York ER - TY - JOUR A1 - Gerecke, Christian A1 - Mascher, Conny A1 - Gottschalk, Uwe A1 - Kleuser, Burkhard A1 - Scholtka, Bettina T1 - Ultrasensitive detection of unknown colon cancer-initiating mutations using the example of the adenomatous polyposis coli gene JF - Cancer prevention research N2 - Detection of cancer precursors contributes to cancer prevention, for example, in the case of colorectal cancer. To record more patients early, ultrasensitive methods are required for the purpose of noninvasive precursor detection in body fluids. Our aim was to develop a method for enrichment and detection of known as well as unknown driver mutations in the Adenomatous polyposis coli (APC) gene. By coupled wild-type blocking (WTB) PCR and high-resolution melting (HRM), referred to as WTB-HRM, a minimum detection limit of 0.01% mutant in excess wild-type was achieved according to as little as 1 pg mutated DNA in the assay. The technique was applied to 80 tissue samples from patients with colorectal cancer (n = 17), adenomas (n = 50), serrated lesions (n = 8), and normal mucosa (n = 5). Any kind of known and unknown APC mutations (deletions, insertions, and base exchanges) being situated inside the mutation cluster region was distinguishable from wild-type DNA. Furthermore, by WTB-HRM, nearly twice as many carcinomas and 1.5 times more precursor lesions were identified to be mutated in APC, as compared with direct sequencing. By analyzing 31 associated stool DNA specimens all but one of the APC mutations could be recovered. Transferability of the WTB-HRM method to other genes was proven using the example of KRAS mutation analysis. In summary, WTB-HRM is a new approach for ultrasensitive detection of cancer-initiating mutations. In this sense, it appears especially applicable for noninvasive detection of colon cancer precursors in body fluids with excess wild-type DNA like stool. Cancer Prev Res; 6(9); 898-907. (C) 2013 AACR. Y1 - 2013 U6 - https://doi.org/10.1158/1940-6207.CAPR-13-0145 SN - 1940-6207 VL - 6 IS - 9 SP - 898 EP - 907 PB - American Association for Cancer Research CY - Philadelphia ER - TY - JOUR A1 - Eschenlohr, Andrea A1 - Battiato, Marco A1 - Maldonado, R. A1 - Pontius, N. A1 - Kachel, T. A1 - Holldack, K. A1 - Mitzner, Rolf A1 - Föhlisch, Alexander A1 - Oppeneer, P. M. A1 - Stamm, C. T1 - Ultrafast spin transport as key to femtosecond demagnetization JF - Nature materials N2 - Irradiating a ferromagnet with a femtosecond laser pulse is known to induce an ultrafast demagnetization within a few hundred femtoseconds. Here we demonstrate that direct laser irradiation is in fact not essential for ultrafast demagnetization, and that electron cascades caused by hot electron currents accomplish it very efficiently. We optically excite a Au/Ni layered structure in which the 30 nm Au capping layer absorbs the incident laser pump pulse and subsequently use the X-ray magnetic circular dichroism technique to probe the femtosecond demagnetization of the adjacent 15 nm Ni layer. A demagnetization effect corresponding to the scenario in which the laser directly excites the Ni film is observed, but with a slight temporal delay. We explain this unexpected observation by means of the demagnetizing effect of a superdiffusive current of non-equilibrium, non-spin-polarized electrons generated in the Au layer. Y1 - 2013 U6 - https://doi.org/10.1038/NMAT3546 SN - 1476-1122 VL - 12 IS - 4 SP - 332 EP - 336 PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Katayama, T. A1 - Anniyev, Toyli A1 - Beye, Martin A1 - Coffee, Ryan A1 - Dell'Angela, M. A1 - Föhlisch, Alexander A1 - Gladh, J. A1 - Kaya, S. A1 - Krupin, O. A1 - Nilsson, A. A1 - Nordlund, D. A1 - Schlotter, W. F. A1 - Sellberg, J. A. A1 - Sorgenfrei, Nomi A1 - Turner, J. J. A1 - Wurth, W. A1 - Öström, H. A1 - Ogasawara, H. T1 - Ultrafast soft X-ray emission spectroscopy of surface adsorbates using an X-ray free electron laser JF - Journal of electron spectroscopy and related phenomena : the international journal on theoretical and experimental aspects of electron spectroscopy N2 - We report on an experimental system designed to probe chemical reactions on solid surfaces on a sub-picosecond timescale using soft X-ray emission spectroscopy at the Linac Coherent Light Source (LCLS) free electron laser (FEL) at the SLAC National Accelerator Laboratory. We analyzed the O 1s X-ray emission spectra recorded from atomic oxygen adsorbed on a Ru(0001) surface at a synchrotron beamline (SSRL, BL13-2) and an FEL beamline (LCLS, SXR). We have demonstrated conditions that provide negligible amount of FEL induced damage of the sample. In addition we show that the setup is capable of tracking the temporal evolution of electronic structure during a surface reaction of submonolayer quantities of CO molecules desorbing from the surface. KW - X-ray emission spectroscopy KW - Surface science KW - Free electron laser KW - Ultrafast Y1 - 2013 U6 - https://doi.org/10.1016/j.elspec.2013.03.006 SN - 0368-2048 VL - 187 IS - 1 SP - 9 EP - 14 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schick, Daniel A1 - Shayduk, Roman A1 - Bojahr, Andre A1 - Herzog, Marc A1 - von Korff Schmising, Clemens A1 - Gaal, Peter A1 - Bargheer, Matias T1 - Ultrafast reciprocal-space mapping with a convergent beam JF - JOURNAL OF APPLIED CRYSTALLOGRAPHY N2 - A diffractometer setup is presented, based on a laser-driven plasma X-ray source for reciprocal-space mapping with femtosecond temporal resolution. In order to map out the reciprocal space, an X-ray optic with a convergent beam is used with an X-ray area detector to detect symmetrically and asymmetrically diffracted X-ray photons simultaneously. The setup is particularly suited for measuring thin films or imperfect bulk samples with broad rocking curves. For quasi-perfect crystalline samples with insignificant in-plane Bragg peak broadening, the measured reciprocal-space maps can be corrected for the known resolution function of the diffractometer in order to achieve high-resolution rocking curves with improved data quality. In this case, the resolution of the diffractometer is not limited by the convergence of the incoming X-ray beam but is solely determined by its energy bandwidth. Y1 - 2013 U6 - https://doi.org/10.1107/S0021889813020013 SN - 0021-8898 VL - 46 IS - 10 SP - 1372 EP - 1377 PB - WILEY-BLACKWELL CY - HOBOKEN ER - TY - JOUR A1 - Scheffler, Christiane T1 - Types of Body Shape JF - Auxology : Studying Human Growth and Development Y1 - 2013 SN - 978-3-510-65278-5 SP - 28 EP - 29 PB - Schweizerbart Science Publishers CY - Stuttgart ER - TY - CHAP A1 - Gracceva, Giulia A1 - Herde, Antje A1 - Koolhaas, J. M. A1 - Palme, R. A1 - Eccard, Jana A1 - Groothuis, T. G. G. T1 - Turning shy on winter's day effects of season on personality and stress response in Microtus arvalis T2 - Integrative and comparative biology Y1 - 2013 SN - 1540-7063 VL - 53 SP - E80 EP - E80 PB - Oxford Univ. Press CY - Cary ER - TY - JOUR A1 - Trauth, Martin H. T1 - TURBO2 - a MATLAB simulation to study the effects of bioturbation on paleoceanographic time series JF - Computers & geosciences : an international journal devoted to the publication of papers on all aspects of geocomputation and to the distribution of computer programs and test data sets ; an official journal of the International Association for Mathematical Geology N2 - Bioturbation (or benthic mixing) causes significant distortions in marine stable isotope signals and other palaeoceanographic records. Although the influence of bioturbation on these records is well known it has rarely been dealt systematically. The MATLAB program called TURBO2 can be used to simulate the effect of bioturbation on individual sediment particles. It can therefore be used to model the distortion of all physical, chemical, and biological signals in deep-sea sediments, such as Mg/Ca ratios and UK37-based sea-surface temperature (SST) variations. In particular, it can be used to study the distortions in paleoceanographic records that are based on individual sediment particles, such as SST records based on foraminifera assemblages. Furthermore. TURBO2 provides a tool to study the effect of benthic mixing of isotope signals such as C-14, delta O-18, and delta C-13, measured in a stratigraphic carrier such as foraminifera shells. KW - Bioturbation KW - Modeling KW - MATLAB KW - Deep-sea records KW - Foraminifera KW - Stable oxygen isotopes Y1 - 2013 U6 - https://doi.org/10.1016/j.cageo.2013.05.003 SN - 0098-3004 SN - 1873-7803 VL - 61 IS - 12 SP - 1 EP - 10 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Sivanesan, Arumugam A1 - Ly, Khoa H. A1 - Adamkiewicz, Witold A1 - Stiba, Konstanze A1 - Leimkühler, Silke A1 - Weidinger, Inez M. T1 - Tunable electric field enhancement and redox chemistry on TiO2 Island films via covalent attachment to Ag or Au nanostructures JF - The journal of physical chemistry : C, Nanomaterials and interfaces N2 - Ag-TiO2 and Au-TiO2 hybrid electrodes were designed by covalent attachment of TiO2 nanoparticles to Ag or Au electrodes via an organic linker. The optical and electronic properties of these systems were investigated using the cytochrome b(5) (Cyt b(5)) domain of sulfite oxidase, exclusively attached to the TiO2 surface, as a Raman marker and model redox enzyme. Very strong SERR signals of Cyt b(5) were obtained for Ag-supported systems due to plasmonic field enhancement of Ag. Time-resolved surface-enhanced resonance Raman spectroscopic measurements yielded a remarkably fast electron transfer kinetic (k = 60 s(-1)) of Cyt b(5) to Ag. A much lower Raman intensity was observed for Au-supported systems with undefined and slow redox behavior. We explain this phenomenon on the basis of the different potential of zero charge of the two metals that largely influence the electronic properties of the TiO2 island film. Y1 - 2013 U6 - https://doi.org/10.1021/jp4032578 SN - 1932-7447 VL - 117 IS - 22 SP - 11866 EP - 11872 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Van Bel, Michiel A1 - Proost, Sebastian A1 - Van Neste, Christophe A1 - Deforce, Dieter A1 - Van de Peer, Yves A1 - Vandepoele, Klaas T1 - TRAPID - an efficient online tool for the functional and comparative analysis of de novo RNA-Seq transcriptomes JF - Genome biology : biology for the post-genomic era N2 - Transcriptome analysis through next-generation sequencing technologies allows the generation of detailed gene catalogs for non-model species, at the cost of new challenges with regards to computational requirements and bioinformatics expertise. Here, we present TRAPID, an online tool for the fast and efficient processing of assembled RNA-Seq transcriptome data, developed to mitigate these challenges. TRAPID offers high-throughput open reading frame detection, frameshift correction and includes a functional, comparative and phylogenetic toolbox, making use of 175 reference proteomes. Benchmarking and comparison against state-of-the-art transcript analysis tools reveals the efficiency and unique features of the TRAPID system. Y1 - 2013 U6 - https://doi.org/10.1186/gb-2013-14-12-r134 SN - 1465-6906 SN - 1474-760X VL - 14 IS - 12 PB - BioMed Central CY - London ER - TY - JOUR A1 - Kursawe, Jochen A1 - Schulz, Johannes H. P. A1 - Metzler, Ralf T1 - Transient aging in fractional brownian and langevin-equation motion JF - Physical review : E, Statistical, nonlinear and soft matter physics N2 - Stochastic processes driven by stationary fractional Gaussian noise, that is, fractional Brownian motion and fractional Langevin-equation motion, are usually considered to be ergodic in the sense that, after an algebraic relaxation, time and ensemble averages of physical observables coincide. Recently it was demonstrated that fractional Brownian motion and fractional Langevin-equation motion under external confinement are transiently nonergodic-time and ensemble averages behave differently-from the moment when the particle starts to sense the confinement. Here we show that these processes also exhibit transient aging, that is, physical observables such as the time-averaged mean-squared displacement depend on the time lag between the initiation of the system at time t = 0 and the start of the measurement at the aging time t(a). In particular, it turns out that for fractional Langevin-equation motion the aging dependence on ta is different between the cases of free and confined motion. We obtain explicit analytical expressions for the aged moments of the particle position as well as the time-averaged mean-squared displacement and present a numerical analysis of this transient aging phenomenon. Y1 - 2013 U6 - https://doi.org/10.1103/PhysRevE.88.062124 SN - 1539-3755 SN - 1550-2376 VL - 88 IS - 6 PB - American Physical Society CY - College Park ER - TY - JOUR A1 - Chmielewski, Anna K. A1 - Dumont, Hanna A1 - Trautwein, Ulrich T1 - Tracking Effects Depend on Tracking Type BT - An International Comparison of Students’ Mathematics Self-Concept JF - American Educational Research Journal N2 - The aim of the present study was to examine how different types of tracking— between-school streaming, within-school streaming, and course-by-course tracking—shape students’ mathematics self-concept. This was done in an internationally comparative framework using data from the Programme for International Student Assessment (PISA). After controlling for individual and track mean achievement, results indicated that generally for students in course-by-course tracking, high-track students had higher mathematics self-concepts and low-track students had lower mathematics self-concepts. For students in between-school and within-school streaming, the reverse pat- tern was found. These findings suggest a solution to the ongoing debate about the effects of tracking on students’ academic self-concept and suggest that the reference groups to which students compare themselves differ according to the type of tracking. KW - academic self-concept KW - international comparison KW - reference groups KW - social comparison KW - tracking Y1 - 2013 UR - http://journals.sagepub.com/doi/pdf/10.3102/0002831213489843 U6 - https://doi.org/10.3102/0002831213489843 SN - 0002-8312 VL - 50 IS - 5 SP - 926 EP - 957 PB - Sage CY - Thousand Oaks, Calif. ER - TY - JOUR A1 - Knapmeyer-Endrun, Brigitte A1 - Krüger, Frank A1 - Legendre, C. P. A1 - Geissler, Wolfram H. T1 - Tracing the influence of the trans-european suture zone into the mantle transition zone JF - Earth & planetary science letters N2 - Cratons with their thick lithospheric roots can influence the thermal structure, and thus the convective flow, in the surrounding mantle. As mantle temperatures are hard to measure directly, depth variations in the mantle transition zone (MTZ) discontinuities are often employed as a proxy. Here, we use a large new data set of P-receiver functions to map the 410 km and 660 km discontinuities beneath the western edge of the East European Craton and adjacent Phanerozoic Europe across the most fundamental lithospheric boundary in Europe, the Trans-European Suture Zone (TESZ). We observe significantly shorter travel times for conversions from both MTZ discontinuities within the craton, caused by the high velocities of the cratonic root. By contrast, the differential travel time across the MTZ is normal to only slightly raised. This implies that any insulating effect of the cratonic keel does not reach the MTZ. In contrast to earlier observations in Siberia, we do not find any trace of a discontinuity at 520 km depth, which indicates a rather dry MTZ beneath the western edge of the craton. Within most of covered Phanerozoic Europe, the MTZ differential travel time is remarkably uniform and in agreement with standard Earth models. No widespread thermal effects of the various episodes of Caledonian and Variscan subduction that took place during the amalgamation of the continent remain. Only more recent tectonic events, related to Alpine subduction and Quarternary volcanism in the Eifel area, can be traced. While the East European craton shows no distinct imprint into the MTZ, we discover the signature of the TESZ in the MTZ in the form of a linear region of about 350 km width with a 1.5 s increase in differential travel time, which could either be caused by high water content or decreased temperature. Taking into account results of recent S-wave tomographies, raised water content in the MTZ cannot be the main cause for this observation. Accordingly, we explain the increase, equivalent to a 15 km thicker MTZ, by a temperature decrease of about 80 K. We discuss two alternative models for this temperature reduction, either a remnant of subduction or an indication of downwelling due to small-scale, edge-driven convection caused by the contrast in lithospheric thickness across the TESZ. Any subducted lithosphere found in the MTZ at this location is unlikely to be related to Variscan subduction along the TESZ, though, as Eurasia has moved significantly northward since the Variscan orogeny. KW - mantle transition zone KW - Trans-European Suture Zone KW - East European Craton KW - edge-driven convection KW - receiver functions Y1 - 2013 U6 - https://doi.org/10.1016/j.epsl.2012.12.028 SN - 0012-821X SN - 1385-013X VL - 363 SP - 73 EP - 87 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Messerschmidt, Katrin A1 - Heilmann, Katja T1 - Toxin-antigen conjugates as selection tools for antibody producing cells JF - Journal of immunological methods N2 - The generation of antibodies with designated specificity requires cost-intensive and time-consuming screening procedures. Here we present a new method by which hybridoma cells can be selected based on the specificity of the produced antibody by the use of antigen-toxin-conjugates thus eliminating the need of a screening procedure. Initial experiments were done with methotrexate as low molecular weight toxin and fluorescein as model antigen. Methotrexate and a methotrexate-fluorescein conjugate were characterized regarding their toxicity. Afterwards the effect of the fluorescein-specific antibody B13-DE1 on the toxicity of the methotrexate-fluorescein conjugate was determined. Finally, first results showed that hybridoma cells that produce fluorescein specific antibodies are able to grow in the presence of fluorescein-toxin-conjugates. KW - Monoclonal antibody KW - Hybridoma technology KW - Selection of antibody producing cells Y1 - 2013 U6 - https://doi.org/10.1016/j.jim.2012.10.010 SN - 0022-1759 VL - 387 IS - 1-2 SP - 167 EP - 172 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Leunert, Franziska A1 - Grossart, Hans-Peter A1 - Gerhardt, Volkmar A1 - Eckert, Werner T1 - Toxicant induced changes on delayed fluorescence decay kinetics of cyanobacteria and green algae a rapid and sensitive biotest JF - PLoS one N2 - Algal tests have developed into routine tools for testing toxicity of pollutants in aquatic environments. Meanwhile, in addition to algal growth rates, an increasing number of fluorescence based methods are used for rapid and sensitive toxicity measures. The present study stresses the suitability of delayed fluorescence (DF) as a promising parameter for biotests. DF is based on the recombination fluorescence at the reaction centre of photosystem II, which is emitted only by photosynthetically active cells. We analyzed the effects of three chemicals (3-(3,4-dichlorophenyl)-1,1-dimethylurea (DCMU), 3,5 Dichlorophenol (3,5 DCP) and copper) on the shape of the DF decay kinetics for potential use in phytoplankton toxicity tests. The short incubation tests were done with four phytoplankton species, with special emphasis on the cyanobacterium Microcystis aeruginosa. All species exhibited a high sensitivity to DCMU, but cyanobacteria were more affected by copper and less by 3,5 DCP than the tested green algae. Analyses of changes in the DF decay curve in response to the added chemicals indicated the feasibility of the DF decay approach as a rapid and sensitive testing tool. Y1 - 2013 U6 - https://doi.org/10.1371/journal.pone.0063127 SN - 1932-6203 VL - 8 IS - 4 PB - PLoS CY - San Fransisco ER - TY - THES A1 - Galeazzi, Filippo T1 - Towards realistic modeling of relativistic stars Y1 - 2013 CY - Potsdam ER - TY - JOUR A1 - Becher, Matthias A. A1 - Osborne, Juliet L. A1 - Thorbek, Pernille A1 - Kennedy, Peter J. A1 - Grimm, Volker T1 - Towards a systems approach for understanding honeybee decline - a stocktaking and synthesis of existing models JF - Journal of applied ecology : an official journal of the British Ecological Society N2 - 1. The health of managed and wild honeybee colonies appears to have declined substantially in Europe and the United States over the last decade. Sustainability of honeybee colonies is important not only for honey production, but also for pollination of crops and wild plants alongside other insect pollinators. A combination of causal factors, including parasites, pathogens, land use changes and pesticide usage, are cited as responsible for the increased colony mortality. 2. However, despite detailed knowledge of the behaviour of honeybees and their colonies, there are no suitable tools to explore the resilience mechanisms of this complex system under stress. Empirically testing all combinations of stressors in a systematic fashion is not feasible. We therefore suggest a cross-level systems approach, based on mechanistic modelling, to investigate the impacts of (and interactions between) colony and land management. 3. We review existing honeybee models that are relevant to examining the effects of different stressors on colony growth and survival. Most of these models describe honeybee colony dynamics, foraging behaviour or honeybee - varroa mite - virus interactions. 4. We found that many, but not all, processes within honeybee colonies, epidemiology and foraging are well understood and described in the models, but there is no model that couples in-hive dynamics and pathology with foraging dynamics in realistic landscapes. 5. Synthesis and applications. We describe how a new integrated model could be built to simulate multifactorial impacts on the honeybee colony system, using building blocks from the reviewed models. The development of such a tool would not only highlight empirical research priorities but also provide an important forecasting tool for policy makers and beekeepers, and we list examples of relevant applications to bee disease and landscape management decisions. KW - Apis mellifera KW - colony decline KW - feedbacks KW - integrated model KW - multiple stressors KW - predictive systems ecology KW - review Y1 - 2013 U6 - https://doi.org/10.1111/1365-2664.12112 SN - 0021-8901 VL - 50 IS - 4 SP - 868 EP - 880 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Feigenbaum, Anna A1 - McCurdy, Patrick A1 - Frenzel, Fabian T1 - Towards a method for studying affect in (micro)politics - the Campfire Chats Project and the Occupy movement JF - Parallax Y1 - 2013 U6 - https://doi.org/10.1080/13534645.2013.778493 SN - 1353-4645 VL - 19 IS - 2 SP - 21 EP - 37 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Wissel, Jörg A1 - Manack, Aubrey A1 - Brainin, Michael T1 - Toward an epidemiology of poststroke spasticity JF - Neurology : official journal of the American Academy of Neurology N2 - Poststroke spasticity (PSS)-related disability is emerging as a significant health issue for stroke survivors. There is a need for predictors and early identification of PSS in order to minimize complications and maladaptation from spasticity. Reviewing the literature on stroke and upper motor neuron syndrome, spasticity, contracture, and increased muscle tone measured with the Modified Ashworth Scale and the Tone Assessment Scale provided data on the dynamic time course of PSS. Prevalence estimates of PSS were highly variable, ranging from 4% to 42.6%, with the prevalence of disabling spasticity ranging from 2% to 13%. Data on phases of the PSS continuum revealed evidence of PSS in 4% to 27% of those in the early time course (1-4 weeks poststroke), 19% to 26.7% of those in the postacute phase (1-3 months poststroke), and 17% to 42.6% of those in the chronic phase (>3 months poststroke). Data also identified key risk factors associated with the development of spasticity, including lower Barthel Index scores, severe degree of paresis, stroke-related pain, and sensory deficits. Although such indices could be regarded as predictors of PSS and thus enable early identification and treatment, the different measures of PSS used in those studies limit the strength of the findings. To optimize evaluation in the different phases of care, the best possible assessment of PSS would make use of a combination of indicators for clinical impairment, motor performance, activity level, quality of life, and patient-reported outcome measures. Applying these recommended measures, as well as increasing our knowledge of the physiologic predictors of PSS, will enable us to perform clinical and epidemiologic studies that will facilitate identification and early, multimodal treatment. Y1 - 2013 SN - 0028-3878 VL - 80 IS - 1 SP - S13 EP - S19 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Kopinski, Stephan A1 - Engel, Tilman A1 - Müller, Steffen A1 - Mayer, Frank T1 - Torque-EMG relationship of lower back muscles - a pilot study T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2013 SN - 0195-9131 SN - 1530-0315 VL - 45 IS - 5 SP - 7 EP - 8 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Momtazi, Saeedeh A1 - Naumann, Felix T1 - Topic modeling for expert finding using latent Dirichlet allocation JF - Wiley interdisciplinary reviews : Data mining and knowledge discovery N2 - The task of expert finding is to rank the experts in the search space given a field of expertise as an input query. In this paper, we propose a topic modeling approach for this task. The proposed model uses latent Dirichlet allocation (LDA) to induce probabilistic topics. In the first step of our algorithm, the main topics of a document collection are extracted using LDA. The extracted topics present the connection between expert candidates and user queries. In the second step, the topics are used as a bridge to find the probability of selecting each candidate for a given query. The candidates are then ranked based on these probabilities. The experimental results on the Text REtrieval Conference (TREC) Enterprise track for 2005 and 2006 show that the proposed topic-based approach outperforms the state-of-the-art profile- and document-based models, which use information retrieval methods to rank experts. Moreover, we present the superiority of the proposed topic-based approach to the improved document-based expert finding systems, which consider additional information such as local context, candidate prior, and query expansion. Y1 - 2013 U6 - https://doi.org/10.1002/widm.1102 SN - 1942-4787 VL - 3 IS - 5 SP - 346 EP - 353 PB - Wiley CY - San Fransisco ER - TY - JOUR A1 - Draude, F. A1 - Galla, S. A1 - Pelster, Axel A1 - Tentschert, J. A1 - Jungnickel, H. A1 - Haase, Alfred A1 - Mantion, Alexandre A1 - Thuenemann, Andreas F. A1 - Taubert, Andreas A1 - Luch, A. A1 - Arlinghaus, H. F. T1 - ToF-SIMS and Laser-SNMS analysis of macrophages after exposure to silver nanoparticles JF - Surface and interface analysis : an international journal devoted to the development and application of techniques for the analysis surfaces, interfaces and thin films N2 - Silver nanoparticles (SNPs) are among the most commercialized nanoparticles because of their antibacterial effects. Besides being employed, e. g. as a coatingmaterial for sterile surfaces in household articles and appliances, the particles are also used in a broad range of medical applications. Their antibacterial properties make SNPs especially useful for wound disinfection or as a coating material for prostheses and surgical instruments. Because of their optical characteristics, the particles are of increasing interest in biodetection as well. Despite the widespread use of SNPs, there is little knowledge of their toxicity. Time-of-flight secondary ion mass spectrometry (ToF-SIMS) and laser post-ionization secondary neutral mass spectrometry (Laser-SNMS) were used to investigate the effects of SNPs on human macrophages derived from THP-1 cells in vitro. For this purpose, macrophages were exposed to SNPs. The SNP concentration ranges were chosen with regard to functional impairments of the macrophages. To optimize the analysis of the macrophages, a special silicon wafer sandwich preparation technique was employed; ToF-SIMS was employed to characterize fragments originating from macrophage cell membranes. With the use of this optimized sample preparation method, the SNP-exposed macrophages were analyzed with ToF-SIMS and with Laser-SNMS. With Laser-SNMS, the three-dimensional distribution of SNPs in cells could be readily detected with very high efficiency, sensitivity, and submicron lateral resolution. We found an accumulation of SNPs directly beneath the cell membrane in a nanoparticular state as well as agglomerations of SNPs inside the cells. KW - Laser-SNMS KW - ToF-SIMS KW - life sciences KW - imaging KW - nanoparticles KW - three-dimensional depth profiling Y1 - 2013 U6 - https://doi.org/10.1002/sia.4902 SN - 0142-2421 VL - 45 IS - 1 SP - 286 EP - 289 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Tentschert, J. A1 - Draude, F. A1 - Jungnickel, H. A1 - Haase, A. A1 - Mantion, Alexandre A1 - Galla, S. A1 - Thuenemann, Andreas F. A1 - Taubert, Andreas A1 - Luch, A. A1 - Arlinghaus, H. F. T1 - TOF-SIMS analysis of cell membrane changes in functional impaired human macrophages upon nanosilver treatment JF - Surface and interface analysis : an international journal devoted to the development and application of techniques for the analysis surfaces, interfaces and thin films N2 - Silver nanoparticles (SNP) are among the most commercialized nanoparticles. Here, we show that peptide-coated SNP cause functional impairment of human macrophages. A dose-dependent inhibition of phagocytosis is observed after nanoparticle treatment, and pretreatment of cells with N-acetyl cysteine (NAC) can counteract the phagocytosis disturbances caused by SNP. Using the surface-sensitive mode of time-of-flight secondary ion mass spectrometry, in combination with multivariate statistical methods, we studied the composition of cell membranes in human macrophages upon exposure to SNP with and without NAC preconditioning. This method revealed characteristic changes in the lipid pattern of the cellular membrane outer leaflet in those cells challenged by SNP. Statistical analyses resulted in 19 characteristic ions, which can be used to distinguish between NAC pretreated and untreated macrophages. The present study discusses the assignments of surface cell membrane phospholipids for the identified ions and the resulting changes in the phospholipid pattern of treated cells. We conclude that the adverse effects in human macrophages caused by SNP can be partially reversed through NAC administration. Some alterations, however, remained. KW - silver nanoparticles KW - lipidomics KW - N-acetyl cysteine KW - phagocytosis KW - oxidative stress Y1 - 2013 U6 - https://doi.org/10.1002/sia.5155 SN - 0142-2421 VL - 45 IS - 1 SP - 483 EP - 485 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Sagolla, Kristina A1 - Löhmannsröben, Hans-Gerd A1 - Hille, Carsten T1 - Time-resolved fluorescence microscopy for quantitative Ca2+ imaging in living cells JF - Analytical & bioanalytical chemistry N2 - Calcium (Ca2+) is a ubiquitous intracellular second messenger and involved in a plethora of cellular processes. Thus, quantification of the intracellular Ca2+ concentration ([Ca2+](i)) and of its dynamics is required for a comprehensive understanding of physiological processes and potential dysfunctions. A powerful approach for studying [Ca2+](i) is the use of fluorescent Ca2+ indicators. In addition to the fluorescence intensity as a common recording parameter, the fluorescence lifetime imaging microscopy (FLIM) technique provides access to the fluorescence decay time of the indicator dye. The nanosecond lifetime is mostly independent of variations in dye concentration, allowing more reliable quantification of ion concentrations in biological preparations. In this study, the feasibility of the fluorescent Ca2+ indicator Oregon Green Bapta-1 (OGB-1) for two-photon fluorescence lifetime imaging microscopy (2P-FLIM) was evaluated. In aqueous solution, OGB-1 displayed a Ca2+-dependent biexponential fluorescence decay behaviour, indicating the presence of a Ca2+-free and Ca2+-bound dye form. After sufficient dye loading into living cells, an in situ calibration procedure has also unravelled the Ca2+-free and Ca2+-bound dye forms from a global biexponential fluorescence decay analysis, although the dye's Ca2+ sensitivity is reduced. Nevertheless, quantitative [Ca2+](i) recordings and its stimulus-induced changes in salivary gland cells could be performed successfully. These results suggest that OGB-1 is suitable for 2P-FLIM measurements, which can gain access to cellular physiology. KW - Fluorescence lifetime KW - TCSPC KW - Two-photon excitation KW - 2P cross section KW - Epithelial ion transport KW - OGB-1 Y1 - 2013 U6 - https://doi.org/10.1007/s00216-013-7290-6 SN - 1618-2642 VL - 405 IS - 26 SP - 8525 EP - 8537 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Beye, Martin A1 - Wernet, Ph. A1 - Schüßler-Langeheine, Christian A1 - Föhlisch, Alexander T1 - Time resolved resonant inelastic X-ray scattering: a supreme tool to understand dynamics in solids and molecules JF - Journal of electron spectroscopy and related phenomena : the international journal on theoretical and experimental aspects of electron spectroscopy N2 - Dynamics in materials typically involve different degrees of freedom, like charge, lattice, orbital and spin in a complex interplay. Time-resolved resonant inelastic X-ray scattering (RIXS) as a highly selective tool can provide unique insight and follow the details of dynamical processes while resolving symmetries, chemical and charge states, momenta, spin configurations, etc. In this paper, we review examples where the intrinsic scattering duration time is used to study femtosecond phenomena. Free-electron lasers access timescales starting in the sub-ps range through pump-probe methods and synchrotrons study the time scales longer than tens of ps. In these examples, time-resolved resonant inelastic X-ray scattering is applied to solids as well as molecular systems. KW - Resonant inelastic X-ray scattering KW - Ultrafast spectroscopy KW - Phase transitions KW - Molecular dynamics Y1 - 2013 U6 - https://doi.org/10.1016/j.elspec.2013.04.013 SN - 0368-2048 VL - 188 IS - 3 SP - 172 EP - 182 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Muksin, Umar A1 - Haberland, Christian A1 - Bauer, Klaus A1 - Weber, Michael H. T1 - Three-dimensional upper crustal structure of the geothermal system in Tarutung (North Sumatra, Indonesia) revealed by seismic attenuation tomography JF - Geophysical journal international N2 - The geothermal potential in Tarutung is controlled by both the Sumatra Fault system and young arc volcanism. In this study we use the spatial distribution of seismic attenuation, calculated from local earthquake recordings, to image the 3-D seismic attenuation of the area and relate it with the temperature anomalies and the fluid distribution of the subsurface. A temporary seismic network of 42 stations was deployed around Tarutung and Sarulla (south of Tarutung) for a period of 10 months starting in 2011 May. Within this period, the network recorded 2586 local events. A high-quality subset of 229 events recorded by at least 10 stations was used for the attenuation inversion (tomography). Path-average attenuation (t(p)*) was calculated by using a spectral inversion method. The spread function, the contour lines of the model resolution matrix and the recovery test results show that our 3-D attenuation model (Q(p)) has good resolution around the Tarutung Basin and along the Sarulla graben. High attenuation (low Q(p)) related to the geothermal system is found in the northeast of the Tarutung Basin suggesting fluid pathways from below the Sumatra Fault. The upper part of the studied geothermal system in the Tarutung district seems to be mainly controlled by the fault structure rather than by magmatic activities. In the southwest of the Tarutung Basin, the high attenuation zone is associated with the Martimbang volcano. In the Sarulla region, a low-Q(p) anomaly is found along the graben within the vicinity of the Hopong caldera. KW - Seismicity and tectonics KW - Body waves KW - Seismic attenuation KW - Seismic tomography Y1 - 2013 U6 - https://doi.org/10.1093/gji/ggt383 SN - 0956-540X SN - 1365-246X VL - 195 IS - 3 SP - 2037 EP - 2049 PB - Oxford Univ. Press CY - Oxford ER - TY - CHAP A1 - Reschke, Antje A1 - Müller, Juliane A1 - Müller, Steffen A1 - Engel, Tilman A1 - Mayer, Frank T1 - Three-dimensional spine kinematics during perturbed treadmill walking - a pilot study T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2013 SN - 0195-9131 SN - 1530-0315 VL - 45 IS - 5 SP - 172 EP - 172 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Conradt, Tobias A1 - Wechsung, F. A1 - Bronstert, Axel T1 - Three perceptions of the evapotranspiration landscape comparing spatial patterns from a distributed hydrological model, remotely sensed surface temperatures, and sub-basin water balances JF - Hydrology and earth system sciences : HESS N2 - A problem encountered by many distributed hydrological modelling studies is high simulation errors at interior gauges when the model is only globally calibrated at the outlet. We simulated river runoff in the Elbe River basin in central Europe (148 268 km(2)) with the semi-distributed eco-hydrological model SWIM (Soil and Water Integrated Model). While global parameter optimisation led to Nash-Sutcliffe efficiencies of 0.9 at the main outlet gauge, comparisons with measured runoff series at interior points revealed large deviations. Therefore, we compared three different strategies for deriving sub-basin evapotranspiration: (1) modelled by SWIM without any spatial calibration, (2) derived from remotely sensed surface temperatures, and (3) calculated from long-term precipitation and discharge data. The results show certain consistencies between the modelled and the remote sensing based evapotranspiration rates, but there seems to be no correlation between remote sensing and water balance based estimations. Subsequent analyses for single sub-basins identify amongst others input weather data and systematic error amplification in inter-gauge discharge calculations as sources of uncertainty. The results encourage careful utilisation of different data sources for enhancements in distributed hydrological modelling. Y1 - 2013 U6 - https://doi.org/10.5194/hess-17-2947-2013 SN - 1027-5606 VL - 17 IS - 7 SP - 2947 EP - 2966 PB - Copernicus CY - Göttingen ER - TY - THES A1 - Fiedler, Sebastian T1 - Thermodynamic stability of the a-Helical membrane-interacting protein mistic in detergent micelles Y1 - 2013 CY - Potsdam ER - TY - JOUR A1 - Macaulay, Euan A. A1 - Sobel, Edward A1 - Mikolaichuk, Alexander A1 - Landgraf, Angela A1 - Kohn, Barry A1 - Stuart, Finlay T1 - Thermochronologic insight into late Cenozoic deformation in the basement-cored Terskey Range, Kyrgyz Tien Shan JF - Tectonics N2 - Basement-cored ranges formed by reverse faulting within intracontinental mountain belts are often composed of poly-deformed lithologies. Geological data capable of constraining the timing, magnitude, and distribution of the most recent deformational phase are usually missing in such ranges. In this paper, we present new low temperature thermochronological and geological data from a transect through the basement-cored Terskey Range, located in the Kyrgyz Tien Shan. Using these data, we are able to investigate the range's late Cenozoic deformation for the first time. Displacements on reactivated faults are constrained and deformation of thermochronologically derived structural markers is assessed. These structural markers postdate the earlier deformational phases, providing the only record of Cenozoic deformation and of the reactivation of structures within the Terskey Range. Overall, these structural markers have a southern inclination, interpreted to reflect the decreasing inclination of the reverse fault bounding the Terskey Range. Our thermochronological data are also used to investigate spatial and temporal variations in the exhumation of the Terskey Range, identifying a three-stage Cenozoic exhumation history: (1) virtually no exhumation in the Paleogene, (2) increase to slightly higher exhumation rates at similar to 26-20Ma, and (3) significant increase in exhumation starting at similar to 10Ma. KW - Thermochronology KW - Basement-cored ranges KW - Tien Shan KW - Structural geology Y1 - 2013 U6 - https://doi.org/10.1002/tect.20040 SN - 0278-7407 VL - 32 IS - 3 SP - 487 EP - 500 PB - American Geophysical Union CY - Washington ER - TY - THES A1 - Günther, Frank T1 - Thermo-erosion of permafrost coasts in East Siberia Y1 - 2013 CY - Potsdam ER - TY - JOUR A1 - Negro, Francois A1 - Bousquet, Romain A1 - Vils, Flurin A1 - Pellet, Clara-Marine A1 - Hänggi-Schaub, Jeanette T1 - Thermal structure and metamorphic evolution of the Piemont-Ligurian metasediments in the northern Western Alps JF - Swiss journal of geosciences N2 - In the Western Alps, the Piemont-Ligurian oceanic domain records blueschist to eclogite metamorphic conditions during the Alpine orogeny. This domain is classically divided into two "zones" (Combin and Zermatt-Saas), with contrasting metamorphic evolution, and separated tectonically by the Combin fault. This study presents new metamorphic and temperature (RSCM thermometry) data obtained in Piemont-Ligurian metasediments and proposes a reevaluation of the P-T evolution of this domain. In the upper unit (or "Combin zone") temperatures are in the range of 420-530 A degrees C, with an increase of temperature from upper to lower structural levels. Petrological evidences show that these temperatures are related to the retrograde path and to deformation at greenschist metamorphic conditions. This highlights heating during exhumation of HP metamorphic rocks. In the lower unit (or "Zermatt-Saas zone"), temperatures are very homogeneous in the range of 500-540 A degrees C. This shows almost continuous downward temperature increase in the Piemont-Ligurian domain. The observed thermal structure is interpreted as the result of the upper and lower unit juxtaposition along shear zones at a temperature of similar to 500 A degrees C during the Middle Eocene. This juxtaposition probably occurred at shallow crustal levels (similar to 15-20 km) within a subduction channel. We finally propose that the Piemont-Ligurian Domain should not be viewed as two distinct "zones", but rather as a stack of several tectonic slices. KW - RSCM thermometry KW - Zermatt-Saas KW - Combin KW - Cignana KW - HP and UHP metamorphism Y1 - 2013 U6 - https://doi.org/10.1007/s00015-013-0119-7 SN - 1661-8726 VL - 106 IS - 1 SP - 63 EP - 78 PB - Springer CY - Basel ER - TY - JOUR A1 - Düsterhöft, Erik A1 - de Capitani, Christian T1 - Theriak_D - an add-on to implement equilibrium computations in geodynamic models JF - Geochemistry, geophysics, geosystems N2 - This study presents the theory, applicability, and merits of the new THERIAK_D add-on for the open source Theriak/Domino software package. The add-on works as an interface between Theriak and user-generated scripts, providing the opportunity to process phase equilibrium computation parameters in a programming environment (e. g., C or MATLABV (R)). THERIAK_D supports a wide range of features such as calculating the solid rock density or testing the stability of mineral phases along any pressure-temperature (P-T) path and P-T grid. To demonstrate applicability, an example is given in which the solid rock density of a 2-D-temperature-pressure field is calculated, portraying a simplified subduction zone. Consequently, the add-on effectively combines thermodynamics and geodynamic modeling. The carefully documented examples could be easily adapted for a broad range of applications. THERIAK_D is free, and the program, user manual, and source codes may be downloaded from http://www.min.unikiel.de/similar to ed/theriakd/. KW - geodynamic modeling KW - thermodynamic modeling KW - Theriak/Domino KW - equilibrium assemblage KW - software Y1 - 2013 U6 - https://doi.org/10.1002/ggge.20286 SN - 1525-2027 VL - 14 IS - 11 SP - 4962 EP - 4967 PB - American Geophysical Union CY - Washington ER - TY - VIDEO A1 - Czyżydło, Klemens A1 - Dödtmann, Eik T1 - There Is No Return To Egypt N2 - Wer sind die polnischen Juden, die in Folge der Antizionistischen Kampagne des Jahres 1968 ihr Heimatland verließen und nach Israel emigrierten? Wie blicken sie, 40 Jahre nach den traumatischen Erlebnissen, auf ihre eigene Geschichte zurück? Welche Entwicklungen machten sie in dem durch zahllose Kriege und innenpolitische Spannungen zerrissenen jüdischen Staat? Wie leben sie im Israel des beginnenden 21. Jahrhunderts? Der Dokumentarfilm There Is No Return To Egypt stellt sieben Vertreter der polnisch- jüdischen Migrationskohorte der ausgehenden 1960er, frühen 1970er Jahre und deren heutiges Umfeld vor. Die Menschen, zum Zeitpunkt der Aufnahmen zwischen Mitte 50 und Ende 70 Jahre alt, erlauben dem Filmteam dabei einen intimen Einblick in ihr israelisch-polnisches Alltagsleben und in ihre Erinnerungswelt. Die älteren Interviewpartnerinnen ziehen aus den Gräueln der selbst noch durchlittenen Schoah und der gut 20 Jahre späteren, erzwungenen Migration aus Polen ihre ganze eigenen Schlüsse für ihr Leben in Israel. Die jüngeren Interviewten gehen wiederum sehr unterschiedlich mit dem Verlust der Heimat und dem Bruch ihrer Erwerbsbiographie im Zuge der Antizionistischen Kampagne um. Die im Film vorgestellten Persönlichkeiten reichen vom erfolgreichen Musiker, über eine ehemalige Mitarbeiterin des israelischen Fernsehens bis hin zu einfachen Facharbeitern. Auch die religiösen Identitäten der Protagonisten sind vielschichtig: von orthodox-nationalreligiös, über atheistisch bis hin zu judeo-christlich. N2 - Who are those Polish Jews, who in the wake of the Antizionist Campaign of the year 1968 left their home country and migrated to Israel? How do they, 40 years after these traumatic events, look back at their own history? Which development have they made in the Jewish State, a society torn by wars and inner political tensions? How do they live in Israel at the beginning of the 21st century? In the documentary There Is No Return To Egypt seven members of the Polish-Jewish migration cohort of the late 1960s, early 1970s and there todays environment are represented. These people, while being on camera in their mid-fifties till late seventies of age, allow an intimate view into their Israeli-Polish daily-life and into their world of memories. Interestingly, having survived the atrocities of the Shoah and being forced out of Poland some twenty years later, the older interviewees draw their very own conclusions for their further lives in Israel. In contrast, the younger interviewees deal very differently with the loss of their home and the break in their career life caused by the Antizionist Campaign. The personalities presented in this documentary have various professions: There is a successful musician, a former employee at the Israeli broadcasting service, and there are skilled workers. Their religious identities widely vary: from Jewish orthodox and national-religious to atheist to Judeo-Christian. The protagonists in There Is No Return To Egypt do also represent the political spectrum of Israel: from members of the chauvinist-militarist camp through to members of the peace movement. At the same time, the shooting locations in the documentary are important stages of life for the seven 1968ers: the home being decorated for Shabbat or for Israels national holiday Yom ha-atzmaut, the working place, an army museum, a Jewish settlement in the Palestinian Westbank, a Shoah memorial event at the university campus, a pop concert and a peace demonstration. KW - Antisemitism KW - Antizionist Campaign KW - Polish Jews KW - Israel KW - migration KW - Antisemitismus KW - Antizionistische Kampagne KW - Polnische Juden KW - Israel KW - Migration Y1 - 2013 UR - https://nbn-resolving.org/urn:nbn:de:kobv:517-mms-108-508-2-2 N1 - Dokumentarfilm in hebräischer und polnischer Sprache mit englischen und deutschen Untertiteln PB - Universitätsverlag CY - Potsdam ER - TY - JOUR A1 - Ignace, Rico A1 - Gayley, Kenneth G. A1 - Hamann, Wolf-Rainer A1 - Huenemoerder, David P. A1 - Oskinova, Lida A1 - Pollock, Andy M. T. A1 - McFall, Michael T1 - THE XMM-NEWTON/EPIC X-RAY LIGHT CURVE ANALYSIS OF WR 6 JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We obtained four pointings of over 100 ks each of the well-studied Wolf-Rayet star WR 6 with the XMM-Newton satellite. With a first paper emphasizing the results of spectral analysis, this follow-up highlights the X-ray variability clearly detected in all four pointings. However, phased light curves fail to confirm obvious cyclic behavior on the well-established 3.766 day period widely found at longer wavelengths. The data are of such quality that we were able to conduct a search for event clustering in the arrival times of X-ray photons. However, we fail to detect any such clustering. One possibility is that X-rays are generated in a stationary shock structure. In this context we favor a corotating interaction region (CIR) and present a phenomenological model for X-rays from a CIR structure. We show that a CIR has the potential to account simultaneously for the X-ray variability and constraints provided by the spectral analysis. Ultimately, the viability of the CIR model will require both intermittent long-term X-ray monitoring of WR 6 and better physical models of CIR X-ray production at large radii in stellar winds. KW - stars: individual (WR 6) KW - stars: winds, outflows KW - stars: Wolf-Rayet KW - X-rays: stars Y1 - 2013 U6 - https://doi.org/10.1088/0004-637X/775/1/29 SN - 0004-637X VL - 775 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - THES A1 - Meyer, Lars T1 - The working memory of argument - verb dependencies : spatiotemporal brain dynamics during sentence processing T2 - MPI Series in human cognitive and brain sciences Y1 - 2013 SN - 978-3-941504-29-5 VL - 145 PB - Max Planck Inst. for Human Cognitive and Brain Sciences CY - Leipzig ER - TY - JOUR A1 - Klettke, Cornelia T1 - The voice of the other : heterotopy and heterology inBernard-Marie Koltes black battles with dogs Y1 - 2013 ER - TY - JOUR A1 - van Loon, Jacco Th. A1 - Bailey, M. A1 - Tatton, B. L. A1 - Apellaniz, Jesus Maiz A1 - Crowther, P. A. A1 - de Koter, A. A1 - Evans, C. J. A1 - Henault-Brunet, V. A1 - Howarth, I. D. A1 - Richter, Philipp A1 - Sana, Hugues A1 - Simon Díaz, Sergio A1 - Taylor, W. A1 - Walborn, N. R. T1 - The VLT-FLAMES tarantula survey IX. - the interstellar medium seen through diffuse interstellar bands and neutral sodium JF - Astronomy and astrophysics : an international weekly journal N2 - Context. The Tarantula Nebula (a.k.a. 30 Dor) is a spectacular star-forming region in the Large Magellanic Cloud (LMC), seen through gas in the Galactic disc and halo. Diffuse interstellar bands (DIBs) offer a unique probe of the diffuse, cool-warm gas in these regions. Aims. The aim is to use DIBs as diagnostics of the local interstellar conditions, whilst at the same time deriving properties of the yet-unknown carriers of these enigmatic spectral features. Methods. Spectra of over 800 early-type stars from the Very Large Telescope Flames Tarantula Survey (VFTS) were analysed. Maps were created, separately, for the Galactic and LMC absorption in the DIBs at 4428 and 6614 angstrom and - in a smaller region near the central cluster R 136 - neutral sodium (the Na ID doublet); we also measured the DIBs at 5780 and 5797 angstrom. Results. The maps show strong 4428 and 6614 angstrom DIBs in the quiescent cloud complex to the south of 30 Dor but weak absorption in the harsher environments to the north (bubbles) and near the OB associations. The Na maps show at least five kinematic components in the LMC and a shell-like structure surrounding R 136, and small-scale structure in the Milky Way. The strengths of the 4428, 5780, 5797 and 6614 angstrom DIBs are correlated, also with Na absorption and visual extinction. The strong 4428 angstrom DIB is present already at low Na column density but the 6614, 5780 and 5797 angstrom DIBs start to be detectable at subsequently larger Na column densities. Conclusions. The carriers of the 4428, 6614, 5780 and 5797 angstrom DIBs are increasingly prone to removal from irradiated gas. The relative strength of the 5780 and 5797 angstrom DIBs clearly confirm the Tarantula Nebula as well as Galactic high-latitude gas to represent a harsh radiation environment. The resilience of the 4428 angstrom DIB suggests its carrier is large, compact and neutral. Structure is detected in the distribution of cool-warm gas on scales between one and > 100 pc in the LMC and as little as 0.01 pc in the Sun's vicinity. Stellar winds from the central cluster R 136 have created an expanding shell; some infalling gas is also detected, reminiscent of a galactic "fountain". KW - ISM: individual objects: Tarantula Nebula (30 Doradus Nebula) KW - ISM: molecules KW - ISM: kinematics and dynamics KW - ISM: lines and bands KW - ISM: structure KW - local insterstellar matter Y1 - 2013 U6 - https://doi.org/10.1051/0004-6361/201220210 SN - 0004-6361 VL - 550 IS - 9 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Molaro, P. A1 - Centurion, Martin A1 - Whitmore, J. B. A1 - Evans, T. M. A1 - Murphy, M. T. A1 - Agafonova, I. I. A1 - Bonifacio, P. A1 - D'Odorico, S. A1 - Levshakov, S. A. A1 - Lopez, S. A1 - Martins, C. J. A. P. A1 - Petitjean, P. A1 - Rahmani, H. A1 - Reimers, D. A1 - Srianand, R. A1 - Vladilo, G. A1 - Wendt, Martin T1 - The UVES Large Program for testing fundamental physics I. Bounds on a change in alpha towards quasar HE 221-2818 JF - Astronomy and astrophysics : an international weekly journal N2 - Context. Absorption-line systems detected in quasar spectra can be used to compare the value of the fine-structure constant, alpha, measured today on Earth with its value in distant galaxies. In recent years, some evidence has emerged of small temporal and also spatial variations in alpha on cosmological scales. These variations may reach a fractional level of approximate to 10 ppm (parts per million). Aims. To test these claims we are conducting a Large Program of observations with the Very Large Telescope's Ultraviolet and Visual Echelle Spectrograph (UVES), and are obtaining high-resolution (R approximate to 60 000) and high signal-to-noise ratio (S/N approximate to 100) UVES spectra calibrated specifically for this purpose. Here we analyse the first complete quasar spectrum from this programme, that of HE 2217-2818. Methods. We applied the many multiplet method to measure alpha in five absorption systems towards this quasar: z(abs) = 0.7866, 0.9424, 1.5558, 1.6279, and 1.6919. Results. The most precise result is obtained for the absorber at z(abs) = 1.6919 where 3 Fe II transitions and Al II lambda 1670 have high S/N and provide a wide range of sensitivities to alpha. The absorption profile is complex with several very narrow features, and it requires 32 velocity components to be fitted to the data. We also conducted a range of tests to estimate the systematic error budget. Our final result for the relative variation in alpha in this system is Delta alpha/alpha = +1.3 +/- 2.4(stat) +/- 1.0(sys) ppm. This is one of the tightest current bounds on alpha-variation from an individual absorber. A second, separate approach to the data reduction, calibration, and analysis of this system yielded a slightly different result of -3.8 +/- 2.1(stat) ppm, possibly suggesting a larger systematic error component than our tests indicated. This approach used an additional 3 Fe II transitions, parts of which were masked due to contamination by telluric features. Restricting this analysis to the Fe II transitions alone and using a modified absorption profile model gave a result that is consistent with the first approach, Delta alpha/alpha = +1.1 +/- 2.6(stat) ppm. The four other absorbers have simpler absorption profiles, with fewer and broader features, and offer transitions with a narrower range of sensitivities to alpha. They therefore provide looser bounds on Delta alpha/alpha at the greater than or similar to 10 ppm precision level. Conclusions. The absorbers towards quasar HE 2217-2818 reveal no evidence of any variation in alpha at the 3-ppm precision level (1 sigma confidence). If the recently reported 10-ppm dipolar variation in alpha across the sky is correct, the expectation at this sky position is (3.2-5.4) +/- 1.7 ppm depending on dipole model used. Our constraint of Delta alpha/alpha = +1.3 +/- 2.4(stat) +/- 1.0(sys) ppm is not inconsistent with this expectation. KW - quasars: absorption lines KW - quasars: individual: HE 2217-2818 KW - intergalactic medium KW - cosmology: miscellaneous cosmology KW - observations Y1 - 2013 U6 - https://doi.org/10.1051/0004-6361/201321351 SN - 0004-6361 VL - 555 IS - 4 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Rahmani, H. A1 - Wendt, Martin A1 - Srianand, R. A1 - Noterdaeme, P. A1 - Petitjean, P. A1 - Molaro, P. A1 - Whitmore, J. B. A1 - Murphy, M. T. A1 - Centurion, Martin A1 - Fathivavsari, H. A1 - D'Odorico, S. A1 - Evans, T. M. A1 - Levshakov, S. A. A1 - Lopez, S. A1 - Martins, C. J. A. P. A1 - Reimers, D. A1 - Vladilo, G. T1 - The UVES large program for testing fundamental physics - II. Constraints on a change in mu towards quasar HE 0027-1836 JF - Monthly notices of the Royal Astronomical Society N2 - We present an accurate analysis of the H-2 absorption lines from the z(abs) similar to 2.4018 damped Ly alpha system towards HE 0027-1836 observed with the Very Large Telescope Ultraviolet and Visual Echelle Spectrograph (VLT/UVES) as a part of the European Southern Observatory Large Programme 'The UVES large programme for testing fundamental physics' to constrain the variation of proton-to-electron mass ratio, mu m(p)/m(e). We perform cross-correlation analysis between 19 individual exposures taken over three years and the combined spectrum to check the wavelength calibration stability. We notice the presence of a possible wavelength-dependent velocity drift especially in the data taken in 2012. We use available asteroids spectra taken with UVES close to our observations to confirm and quantify this effect. We consider single-and two-component Voigt profiles to model the observed H-2 absorption profiles. We use both linear regression analysis and Voigt profile fitting where Delta mu/mu is explicitly considered as an additional fitting parameter. The two-component model is marginally favoured by the statistical indicators and we get Delta mu/mu = -2.5 +/- 8.1(stat) +/- 6.2(sys) ppm. When we apply the correction to the wavelength-dependent velocity drift, we find Delta mu/mu = -7.6 +/- 8.1(stat) +/- 6.3(sys) ppm. It will be important to check the extent to which the velocity drift we notice in this study is present in UVES data used for previous Delta mu/mu measurements. KW - intergalactic medium KW - quasars: absorption lines KW - quasars: individual: HE 0027-1836 Y1 - 2013 U6 - https://doi.org/10.1093/mnras/stt1356 SN - 0035-8711 SN - 1365-2966 VL - 435 IS - 1 SP - 861 EP - 878 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Martin-Martin, J. D. A1 - Gomez-Rivas, E. A1 - Bover-Arnal, T. A1 - Trave, A. A1 - Salas, R. A1 - Moreno-Bedmar, J. A. A1 - Tomas, S. A1 - Corbella, M. A1 - Teixell, A. A1 - Verges, J. A1 - Stafford, S. L. T1 - The Upper Aptian to Lower Albian syn-rift carbonate succession of the southern Maestrat Basin (Spain): Facies architecture and fault-controlled stratabound dolostones JF - CRETACEOUS RESEARCH N2 - Syn-rift shallow-marine carbonates of Late Aptian to Early Albian age in the southern Maestrat Basin (E Spain) register the thickest Aptian sedimentary record of the basin, and one of the most complete carbonate successions of this age reported in the northern Tethyan margin. The host limestones (Benassal Formation) are partially replaced by dolostones providing a new case study of fault-controlled hydrothermal dolomitization. The syn-rift sediments filled a graben controlled by normal basement faults. The Benassal Fm was deposited in a carbonate ramp with scarce siliciclastic input. The lithofacies are mainly characterized by the presence of orbitolinid foraminifera, corals and rudist bivalves fauna. The succession is stacked in three transgressive-regressive sequences (T-R) bounded by surfaces with sequence stratigraphic significance. The third sequence, which is reported for the first time in the basin, is formed by fully marine lithofacies of Albian age and represents the marine equivalent to the continental deposits of the Escucha Fm in the rest of the basin. The dolomitization of the host rock is spatially associated with the basement faults, and thus is fault-controlled. The dolostone forms seismic-scale stratabound tabular geobodies that extend several kilometres away from the fault zones, mostly in the hanging wall blocks, and host Mississippi Valley Type (MVT) deposits. The dolostones preferentially replaced middle to inner ramp grain-dominated fades from the third T-R sequences consisting of bioclastic packestones and peloidal grainstones. Field and petrology data indicate that the replacement took place after early calcite cementation and compaction, most likely during the Late Cretaceous post-rift stage of the basin. The dolostone registers the typical hydrothermal paragenesis constituted by the host limestone replacement, dolomite cementation and sulfide MVT mineralization. The Aptian succession studied provides a stratigraphic framework that can be used for oil exploration in age-equivalent rocks, especially in the Valencia Trough, offshore Spain. Moreover, this new case study constitutes a world class outcrop analogue for similar partially stratabound, dolomitized limestone reservoirs worldwide. (c) 2013 Elsevier Ltd. All rights reserved. KW - Aptian KW - Carbonate platform KW - Fault-controlled KW - Dolomitization KW - Maestrat Basin Y1 - 2013 U6 - https://doi.org/10.1016/j.cretres.2012.12.008 SN - 0195-6671 SN - 1095-998X VL - 41 IS - 4 SP - 217 EP - 236 PB - ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD CY - LONDON ER - TY - CHAP A1 - Hafer, Jörg A1 - Kiy, Alexander ED - Buchem, Ilona ED - Graham, Attwell ED - Tur, Gemma T1 - The university-wide introduction of an ePortfolio system as transdisciplinary task BT - Results of an implementation process and perspectives on an optimized process model T2 - Proceedings of the PLE Conference 2013: Learning and Diversity in the Cities of the Future Y1 - 2013 SP - 363 EP - 373 PB - Logos CY - Berlin ER - TY - JOUR A1 - Bertilsson, Stefan A1 - Burgin, Amy A1 - Carey, Cayelan C. A1 - Fey, Samuel B. A1 - Grossart, Hans-Peter A1 - Grubisic, Lorena M. A1 - Jones, Ian D. A1 - Kirillin, Georgiy A1 - Lennon, Jay T. A1 - Shade, Ashley A1 - Smyth, Robyn L. T1 - The under-ice microbiome of seasonally frozen lakes JF - Limnology and oceanography N2 - Compared to the well-studied open water of the "growing" season, under-ice conditions in lakes are characterized by low and rather constant temperature, slow water movements, limited light availability, and reduced exchange with the surrounding landscape. These conditions interact with ice-cover duration to shape microbial processes in temperate lakes and ultimately influence the phenology of community and ecosystem processes. We review the current knowledge on microorganisms in seasonally frozen lakes. Specifically, we highlight how under-ice conditions alter lake physics and the ways that this can affect the distribution and metabolism of auto-and heterotrophic microorganisms. We identify functional traits that we hypothesize are important for understanding under-ice dynamics and discuss how these traits influence species interactions. As ice coverage duration has already been seen to reduce as air temperatures have warmed, the dynamics of the under-ice microbiome are important for understanding and predicting the dynamics and functioning of seasonally frozen lakes in the near future. Y1 - 2013 U6 - https://doi.org/10.4319/lo.2013.58.6.1998 SN - 0024-3590 SN - 1939-5590 VL - 58 IS - 6 SP - 1998 EP - 2012 PB - Wiley CY - Waco ER - TY - THES A1 - Rohrmann, Johannes T1 - The transcription factors orchestra of ripening tomato fruits Y1 - 2013 CY - Potsdam ER - TY - JOUR A1 - Clahsen, Harald A1 - Balkhair, Loay A1 - Schutter, John-Sebastian A1 - Cunnings, Ian T1 - The time course of morphological processing in a second language JF - Second language research N2 - We report findings from psycholinguistic experiments investigating the detailed timing of processing morphologically complex words by proficient adult second (L2) language learners of English in comparison to adult native (L1) speakers of English. The first study employed the masked priming technique to investigate -ed forms with a group of advanced Arabic-speaking learners of English. The results replicate previously found L1/L2 differences in morphological priming, even though in the present experiment an extra temporal delay was offered after the presentation of the prime words. The second study examined the timing of constraints against inflected forms inside derived words in English using the eye-movement monitoring technique and an additional acceptability judgment task with highly advanced Dutch L2 learners of English in comparison to adult L1 English controls. Whilst offline the L2 learners performed native-like, the eye-movement data showed that their online processing was not affected by the morphological constraint against regular plurals inside derived words in the same way as in native speakers. Taken together, these findings indicate that L2 learners are not just slower than native speakers in processing morphologically complex words, but that the L2 comprehension system employs real-time grammatical analysis (in this case, morphological information) less than the L1 system. KW - compounds KW - derivational morphology KW - English as a seond language KW - inflectional morphology KW - late bilinguals KW - masked priming KW - morphology processing KW - past tense KW - shallow structure hypothesis Y1 - 2013 U6 - https://doi.org/10.1177/0267658312464970 SN - 0267-6583 VL - 29 IS - 1 SP - 7 EP - 31 PB - Sage Publ. CY - London ER - TY - JOUR A1 - Schmidt, Hans-Jürgen T1 - The tetralogy of Birkhoff theorems JF - General relativity and gravitation N2 - We classify the existent Birkhoff-type theorems into four classes: first, in field theory, the theorem states the absence of helicity 0- and spin 0-parts of the gravitational field. Second, in relativistic astrophysics, it is the statement that the gravitational far-field of a spherically symmetric star carries, apart from its mass, no information about the star; therefore, a radially oscillating star has a static gravitational far-field. Third, in mathematical physics, Birkhoff's theorem reads: up to singular exceptions of measure zero, the spherically symmetric solutions of Einstein's vacuum field equation with can be expressed by the Schwarzschild metric; for , it is the Schwarzschild-de Sitter metric instead. Fourth, in differential geometry, any statement of the type: every member of a family of pseudo-Riemannian space-times has more isometries than expected from the original metric ansatz, carries the name Birkhoff-type theorem. Within the fourth of these classes we present some new results with further values of dimension and signature of the related spaces; including them are some counterexamples: families of space-times where no Birkhoff-type theorem is valid. These counterexamples further confirm the conjecture, that the Birkhoff-type theorems have their origin in the property, that the two eigenvalues of the Ricci tensor of 2-D pseudo-Riemannian spaces always coincide, a property not having an analogy in higher dimensions. Hence, Birkhoff-type theorems exist only for those physical situations which are reducible to 2-D. KW - Birkhoff theorem KW - Einstein space KW - Isometry group Y1 - 2013 U6 - https://doi.org/10.1007/s10714-012-1478-5 SN - 0001-7701 VL - 45 IS - 2 SP - 395 EP - 410 PB - Springer CY - New York ER - TY - JOUR A1 - Schmidt, Hans-Jürgen T1 - The tetralogy of Birkhoff theorems N2 - We classify the existent Birkhoff-type theorems into four classes: First, in field theory, the theorem states the absence of helicity 0- and spin 0-parts of the gravitational field. Second, in relativistic astrophysics, it is the statement that the gravitational far-field of a spherically symmetric star carries, apart from its mass, no information about the star; therefore, a radially oscillating star has a static gravitational far-field. Third, in mathematical physics, Birkhoff's theorem reads: up to singular exceptions of measure zero, the spherically symmetric solutions of Einstein's vacuum field equation with Lambda = 0 can be expressed by the Schwarzschild metric; for Lambda unequal 0, it is the Schwarzschild-de Sitter metric instead. Fourth, in differential geometry, any statement of the type: every member of a family of pseudo-Riemannian space-times has more isometries than expected from the original metric ansatz, carries the name Birkhoff-type theorem. Within the fourth of these classes we present some new results with further values of dimension and signature of the related spaces; including them are some counterexamples: families of space-times where no Birkhoff-type theorem is valid. These counterexamples further confirm the conjecture, that the Birkhoff-type theorems have their origin in the property, that the two eigenvalues of the Ricci tensor of two- dimensional pseudo-Riemannian spaces always coincide, a property not having an analogy in higher dimensions. Hence, Birkhoff-type theorems exist only for those physical situations which are reducible to two dimensions. Y1 - 2013 UR - http://arXiv.org/abs/1208.5237 SN - 0001-7701 ER - TY - JOUR A1 - Cheng, Shifeng A1 - van den Bergh, Erik A1 - Zeng, Peng A1 - Zhong, Xiao A1 - Xu, Jiajia A1 - Liu, Xin A1 - Hofberger, Johannes A1 - de Bruijn, Suzanne A1 - Bhide, Amey S. A1 - Kuelahoglu, Canan A1 - Bian, Chao A1 - Chen, Jing A1 - Fan, Guangyi A1 - Kaufmann, Kerstin A1 - Hall, Jocelyn C. A1 - Becker, Annette A1 - Bräutigam, Andrea A1 - Weber, Andreas P. M. A1 - Shi, Chengcheng A1 - Zheng, Zhijun A1 - Li, Wujiao A1 - Lv, Mingju A1 - Tao, Yimin A1 - Wang, Junyi A1 - Zou, Hongfeng A1 - Quan, Zhiwu A1 - Hibberd, Julian M. A1 - Zhang, Gengyun A1 - Zhu, Xin-Guang A1 - Xu, Xun A1 - Schranz, M. Eric T1 - The Tarenaya hassleriana Genome Provides insight Into Reproductive Trait and Genome Evolution of Crucifers JF - The plant cell N2 - The Brassicaceae, including Arabidopsis thaliana and Brassica crops, is unmatched among plants in its wealth of genomic and functional molecular data and has long served as a model for understanding gene, genome, and trait evolution. However, genome information from a phylogenetic outgroup that is essential for inferring directionality of evolutionary change has been lacking. We therefore sequenced the genome of the spider flower (Tarenaya hassleriana) from the Brassicaceae sister family, the Cleomaceae. By comparative analysis of the two lineages, we show that genome evolution following ancient polyploidy and gene duplication events affect reproductively important traits. We found an ancient genome triplication in Tarenaya (Th-alpha) that is independent of the Brassicaceae-specific duplication (At-alpha) and nested Brassica (Br-a) triplication. To showcase the potential of sister lineage genome analysis, we investigated the state of floral developmental genes and show Brassica retains twice as many floral MADS (for MINICHROMOSOME MAINTENANCE1, AGAMOUS, DEFICIENS and SERUM RESPONSE FACTOR) genes as Tarenaya that likely contribute to morphological diversity in Brassica. We also performed synteny analysis of gene families that confer self-incompatibility in Brassicaceae and found that the critical SERINE RECEPTOR KINASE receptor gene is derived from a lineage-specific tandem duplication. The T. hassleriana genome will facilitate future research toward elucidating the evolutionary history of Brassicaceae genomes. Y1 - 2013 U6 - https://doi.org/10.1105/tpc.113.113480 SN - 1040-4651 VL - 25 IS - 8 SP - 2813 EP - 2830 PB - American Society of Plant Physiologists CY - Rockville ER - TY - JOUR A1 - Dahl, Jan-Ulrik A1 - Radon, Christin A1 - Bühning, Martin A1 - Nimtz, Manfred A1 - Leichert, Lars I. A1 - Denis, Yann A1 - Jourlin-Castelli, Cecile A1 - Iobbi-Nivol, Chantal A1 - Mejean, Vincent A1 - Leimkühler, Silke T1 - The Sulfur Carrier Protein TusA Has a Pleiotropic Role in Escherichia coli That Also Affects Molybdenum Cofactor Biosynthesis JF - JOURNAL OF BIOLOGICAL CHEMISTRY N2 - The Escherichia coli L-cysteine desulfurase IscS mobilizes sulfur from L-cysteine for the synthesis of several biomolecules such as iron-sulfur (FeS) clusters, molybdopterin, thiamin, lipoic acid, biotin, and the thiolation of tRNAs. The sulfur transfer from IscS to various biomolecules is mediated by different interaction partners (e.g. TusA for thiomodification of tRNAs, IscU for FeS cluster biogenesis, and ThiI for thiamine biosynthesis/tRNA thiolation), which bind at different sites of IscS. Transcriptomic and proteomic studies of a Delta tusA strain showed that the expression of genes of the moaABCDE operon coding for proteins involved in molybdenum cofactor biosynthesis is increased under aerobic and anaerobic conditions. Additionally, under anaerobic conditions the expression of genes encoding hydrogenase 3 and several molybdoenzymes such as nitrate reductase were also increased. On the contrary, the activity of all molydoenzymes analyzed was significantly reduced in the Delta tusA mutant. Characterization of the Delta tusA strain under aerobic conditions showed an overall low molybdopterin content and an accumulation of cyclic pyranopterin monophosphate. Under anaerobic conditions the activity of nitrate reductase was reduced by only 50%, showing that TusA is not essential for molybdenum cofactor biosynthesis. We present a model in which we propose that the direction of sulfur transfer for each sulfur-containing biomolecule is regulated by the availability of the interaction partner of IscS. We propose that in the absence of TusA, more IscS is available for FeS cluster biosynthesis and that the overproduction of FeS clusters leads to a modified expression of several genes. Y1 - 2013 U6 - https://doi.org/10.1074/jbc.M112.431569 SN - 0021-9258 VL - 288 IS - 8 SP - 5426 EP - 5442 PB - AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC CY - BETHESDA ER - TY - JOUR A1 - Debussche, Arnaud A1 - Högele, Michael A1 - Imkeller, Peter T1 - The stochastic chafee-infante equation JF - Lecture notes in mathematics : a collection of informal reports and seminars JF - Lecture Notes in Mathematics N2 - In this preparatory chapter, the tools of stochastic analysis needed for the investigation of the asymptotic behavior of the stochastic Chafee-Infante equation are provided. In the first place, this encompasses a recollection of basic facts about Lévy processes with values in Hilbert spaces. Playing the role of the additive noise processes perturbing the deterministic Chafee-Infante equation in the systems the stochastic dynamics of which will be our main interest, symmetric ?-stable Lévy processes are in the focus of our investigation (Sect. 3.1). Y1 - 2013 SN - 978-3-319-00828-8; 978-3-319-00827-1 U6 - https://doi.org/10.1007/978-3-319-00828-8_3 SN - 0075-8434 VL - 2085 SP - 45 EP - 68 PB - Springer CY - Berlin ER - TY - JOUR A1 - Debussche, Arnaud A1 - Hoegele, Michael A1 - Imkeller, Peter T1 - The source of stochastic models in conceptual climate dynamics JF - Lecture notes in mathematics : a collection of informal reports and seminars JF - Lecture Notes in Mathematics Y1 - 2013 SN - 978-3-319-00828-8; 978-3-319-00827-1 U6 - https://doi.org/10.1007/978-3-319-00828-8 SN - 0075-8434 VL - 2085 IS - 3 SP - 151 EP - 157 PB - Springer CY - Berlin ER - TY - BOOK A1 - Krahé, Barbara T1 - The social psychology of aggression Y1 - 2013 SN - 978-1-84169-874-8 SN - 978-1-84169-875-5 SN - 978-0-203-08217-1 PB - Psychology Press CY - New York ET - 2nd ed. ER - TY - JOUR A1 - Krahe, Charlotte A1 - Springer, Anne A1 - Weinman, John A. A1 - Fotopoulou, Aikaterini T1 - The social modulation of pain - others as predictive signals of salience ; a systematic review JF - Frontiers in human neuroscienc N2 - Several studies in cognitive neuroscience have investigated the cognitive and affective modulation of pain. By contrast, fewer studies have focused on the social modulation of pain, despite a plethora of relevant clinical findings. Here we present the first review of experimental studies addressing how interpersonal factors, such as the presence, behavior, and spatial proximity of an observer, modulate pain. Based on a systematic literature search, we identified 26 studies on experimentally induced pain that manipulated different interpersonal variables and measured behavioral, physiological, and neural pain-related responses. We observed that the modulation of pain by interpersonal factors depended on (1) the degree to which the social partners were active or were perceived by the participants to possess possibility for action; (2) the degree to which participants could perceive the specific intentions of the social partners; (3) the type of pre-existing relationship between the social partner and the person in pain, and lastly, (4) individual differences in relating to others and coping styles. Based on these findings, we propose that the modulation of pain by social factors can be fruitfully understood in relation to a recent predictive coding model, the free energy framework, particularly as applied to interoception and social cognition. Specifically, we argue that interpersonal interactions during pain may function as social, predictive signals of contextual threat or safety and as such influence the salience of noxious stimuli. The perception of such interpersonal interactions may in turn depend on (a) prior beliefs about interpersonal relating and (b) the certainty or precision by which an interpersonal interaction may predict environmental threat or safety. KW - pain KW - social modulation KW - social support KW - empathy KW - predictive coding KW - attachment KW - review Y1 - 2013 U6 - https://doi.org/10.3389/fnhum.2013.00386 SN - 1662-5161 VL - 7 IS - 29 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Debussche, Arnaud A1 - Hoegele, Michael A1 - Imkeller, Peter T1 - The small deviation of the small noise solution JF - Lecture notes in mathematics : a collection of informal reports and seminars JF - Lecture Notes in Mathematics Y1 - 2013 SN - 978-3-319-00828-8; 978-3-319-00827-1 U6 - https://doi.org/10.1007/978-3-319-00828-8_4 SN - 0075-8434 VL - 2085 SP - 69 EP - 85 PB - Springer CY - Berlin ER - TY - JOUR A1 - Jedrusik-Bode, Monika A1 - Studencka, Maja A1 - Smolka, Christian A1 - Baumann, Tobias A1 - Schmidt, Henning A1 - Kampf, Jan A1 - Paap, Franziska A1 - Martin, Sophie A1 - Tazi, Jamal A1 - Müller, Kristian M. A1 - Krüger, Marcus A1 - Braun, Thomas A1 - Bober, Eva T1 - The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals JF - Journal of cell science N2 - SIRT6 is a NAD(+)-dependent deacetylase that modulates chromatin structure and safeguards genomic stability. Until now, SIRT6 has been assigned to the nucleus and only nuclear targets of SIRT6 are known. Here, we demonstrate that in response to stress, C. elegans SIR-2.4 and its mammalian orthologue SIRT6 localize to cytoplasmic stress granules, interact with various stress granule components and induce their assembly. Loss of SIRT6 or inhibition of its catalytic activity in mouse embryonic fibroblasts impairs stress granule formation and delays disassembly during recovery, whereas deficiency of SIR-2.4 diminishes maintenance of P granules and decreases survival of C. elegans under stress conditions. Our findings uncover a novel, evolutionary conserved function of SIRT6 in the maintenance of stress granules in response to stress. KW - C. elegans KW - G3BP KW - SIRT6 KW - Sirtuins KW - Stress KW - Stress granules Y1 - 2013 U6 - https://doi.org/10.1242/jcs.130708 SN - 0021-9533 SN - 1477-9137 VL - 126 IS - 22 SP - 5166 EP - + PB - Company of Biologists Limited CY - Cambridge ER - TY - JOUR A1 - Muschalla, Beate A1 - Heldmann, Madleen A1 - Fay, Doris T1 - The significance of job-anxiety in a working population JF - Occupational medicine N2 - Background Job-anxiety, as distinguished from trait-anxiety, is associated with long-term sickness absence. The prevalence of job-anxiety within a working population is not known. Identifying individuals who would benefit from intervention might be useful. Aims To investigate job-anxiety in employees not undergoing treatment for mental health illness, firstly by assessing the level of job-anxiety and work-related avoidance tendencies in a working sample, and secondly by testing whether job-anxiety is distinguishable from trait-anxiety. Methods Cross-sectional survey of a convenience sample obtained through personal contact distribution. Employees from different professional settings completed an anonymous questionnaire and provided information on their employment status. The State-Trait-Anxiety Inventory (STAI-T) was used to measure trait-anxiety and the Job-Anxiety-Scale (JAS) was used to assess job (state) anxiety. Results There was a 69% response rate (240 responses); 188 responses were available for analysis of whom 62% were women. There were no employees with high trait-anxiety. Ten employees (5%) reported increased job-anxiety and of these nine employees reported high 'tendencies of avoidance and workplace absence'. Avoidance was most often accompanied by the comorbid job-anxieties 'job-related social anxiety', 'fear of changes at work' and 'fears of existence', 'anticipatory' and 'conditioned' job-anxiety and 'panic symptoms'. Conclusions In this sample, self-reported job-anxiety appeared as a specific type of anxiety as opposed to trait-anxiety. In the workplace job-anxiety can present as job-avoidance and sickness absence and should be distinguished from trait-anxiety. In practice, employers and occupational health practitioners should be aware of those employees prone to sickness absence. KW - Job-anxiety KW - occupational health KW - sickness absence KW - trait-anxiety KW - workplace Y1 - 2013 U6 - https://doi.org/10.1093/occmed/kqt072 SN - 0962-7480 VL - 63 IS - 6 SP - 415 EP - 421 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Zobir, Soraya Hadj A1 - Oberhänsli, Roland T1 - The sidi Mohamed peridotites (Edough Massif, NE Algeria) - evidence for an upper mantle origin JF - Journal of earth system science N2 - The Hercynian Edough massif is the easternmost crystalline massif of the Algerian coast. It consists of two tectonically superposed units composed of micaschists, gneisses, and peridotite. This study concentrates on the small and isolated Sidi Mohamed peridotite outcrop area (0.03 km(2)). The Sidi Mohamed peridotite is composed mainly of harzburgites (Mg-rich olivine and orthopyroxene as major minerals). The Ni (2051-2920 ppm), Cr (2368-5514 ppm) and MgO (similar to 28-35 wt.%) whole-rock composition and the relative depletion in Nb make these harzburgites comparable to depleted peridotites related to a subduction zone. We suggest that the Sidi Mohamed ultramafic body was derived directly from the upper mantle and tectonically incorporated into the gneiss units of the Edough metamorphic core complex in a subduction environment. KW - Peridotites KW - upper mantle KW - Edough KW - Algeria Y1 - 2013 U6 - https://doi.org/10.1007/s12040-013-0358-z SN - 0253-4126 SN - 0973-774X VL - 122 IS - 6 SP - 1455 EP - 1465 PB - Indian Academy of Science CY - Bangalore ER - TY - JOUR A1 - Zimmermann, Andreas T1 - The security council and the obligation to prevent genocide and war crimes Y1 - 2013 ER -