TY  - JOUR
A1  - Sege, Christopher T.
A1  - Bradley, Margaret M.
A1  - Weymar, Mathias
A1  - Lang, Peter J.
T1  - A direct comparison of appetitive and aversive anticipation
BT  - overlapping and distinct neural activation
JF  - Behavioural brain research : an international journal
N2  - fMRI studies of reward find increased neural activity in ventral striatum and medial prefrontal cortex (mPFC), whereas other regions, including the dorsolateral prefrontal cortex (d1PFC), anterior cingulate cortex (ACC), and anterior insula, are activated when anticipating aversive exposure. Although these data suggest differential activation during anticipation of pleasant or of unpleasant exposure, they also arise in the context of different paradigms (e.g., preparation for reward vs. threat of shock) and participants. To determine overlapping and unique regions active during emotional anticipation, we compared neural activity during anticipation of pleasant or unpleasant exposure in the same participants. Cues signalled the upcoming presentation of erotic/romantic, violent, or everyday pictures while BOLD activity during the 9-s anticipatory period was measured using fMRI. Ventral striatum and a ventral mPFC subregion were activated when anticipating pleasant, but not unpleasant or neutral, pictures, whereas activation in other regions was enhanced when anticipating appetitive or aversive scenes.
KW  - Anticipation
KW  - Emotion
KW  - fMRI
Y1  - 2017
U6  - https://doi.org/10.1016/j.bbr.2017.03.005
SN  - 0166-4328
SN  - 1872-7549
VL  - 326
SP  - 96
EP  - 102
PB  - Elsevier
CY  - Amsterdam
ER  -