TY  - JOUR
A1  - Ladwig, Simon
A1  - Volz, Matthias
A1  - Werheid, Katja
T1  - Depression ist weiblich – auch nach Schlaganfall?
T1  - Depression is female - even after stroke?
BT  - Geschlechtervergleich von Diagnosehäufigkeit und depressiver Symptomatik im Quer- und Längsschnitt
BT  - Cross-sectional and longitudinal comparisons of gender effects in prevalence and depressive symptoms
JF  - Zeitschrift für Neuropsychologie
N2  - Während Frauen in der Allgemeinbevölkerung ein höheres Depressionsrisiko aufweisen als Männer, ist die Forschungslage zu Geschlechterunterschieden nach Schlaganfall heterogen. Die vorliegende Längsschnittstudie untersucht Geschlechterunterschiede in der Häufigkeit von depressiven Störungen und Symptomen nach Schlaganfall. An zwei deutschen Rehabilitationszentren wurden N = 174 Schlaganfallpatienten und -patientinnen1 (n = 72 weiblich) rekrutiert und etablierte Risikofaktoren erfasst. Nacherhebungen fanden nach acht und 15 Monaten statt. Depressive Störungen und Symptome waren häufiger bei Frauen (48.2 %) als bei Männern (28.3 %) während der stationären Rehabilitation, jedoch nicht in den Folgeuntersuchungen. Etablierte Risikofaktoren beeinflussten geschlechtsunabhängig die Ausprägung depressiver Symptomatik. In Übereinstimmung mit aktuellen Meta-Analysen zeigten sich keine dauerhaften Geschlechterunterschiede bei Depression nach Schlaganfall. In der klinischen Praxis sollte die Affektlage von Schlaganfallpatienten geschlechtsunabhängig betrachtet werden.
N2  - Depression in the general population is more frequent in women than in men. In depression after stroke however, evidence regarding gender differences is heterogeneous. This study investigates gender differences in frequencies of depressive disorders and symptoms after stroke. Patients (N = 174, n = 72 female) were recruited from two German rehabilitation clinics, assessed for established risk factors seven weeks post-ictus, and followed up eight and 15 months later. Depressive disorders and symptoms were more frequent in women (48.2%) than in men (28.3%) during rehabilitation, but not in follow-up assessments. Established risk factors influenced depressive symptoms irrespectively of gender. In accordance with current meta-analyses, no stable gender differences were found in depression after stroke. In clinical practice, emotional state should be monitored independently from gender.
KW  - Stroke
KW  - depression
KW  - gender
KW  - prospective longitudinal
Y1  - 2018
U6  - https://doi.org/10.1024/1016-264X/a000225
SN  - 1016-264X
SN  - 1664-2902
VL  - 29
IS  - 3
SP  - 141
EP  - 147
PB  - Hogrefe
CY  - Bern
ER  - 
TY  - JOUR
A1  - Ladwig, Simon
A1  - Zhou, Zien
A1  - Xu, Ying
A1  - Wang, Xia
A1  - Chow, Clara K.
A1  - Werheid, Katja
A1  - Hackett, Maree L.
T1  - Comparison of treatment rates of depression after stroke versus myocardial infarction
BT  - a systematic review and meta-analysis of observational data
JF  - Psychosomatic medicine
N2  - Objective Depression after stroke and myocardial infarction (MI) is common but often assumed to be undertreated without reliable evidence being available. Thus, we aimed to determine treatment rates and investigate the application of guidelines in these conditions. Methods Databases MEDLINE, EMBASE, PsycInfo, Web of Science, CINAHL, and Scopus were systematically searched without language restriction from inception to June 30, 2017. Prospective observational studies with consecutive recruitment reporting any antidepressant treatment in adults with depression after stroke or MI were included. Random-effects models were used to calculate pooled estimates of treatment rates. Results Fifty-five studies reported 32 stroke cohorts (n = 8938; pooled frequency of depression = 34%, 95% confidence interval [CI] = 29%-38%) and 17 MI cohorts (n = 10,767; pooled frequency of depression = 24%, 95% CI = 20%-28%). In 29 stroke cohorts, 24% (95% CI = 20%-27%) of 2280 depressed people used antidepressant medication. In 15 MI cohorts, 14% (95% CI = 8%-19%) of 2381 depressed people used antidepressant medication indicating a lower treatment rate than in stroke. Two studies reported use of psychosocial interventions, indicating that less than 10% of participants were treated. Conclusions Despite the high frequency of depression after stroke and MI and the existence of efficacious treatment strategies, people often remain untreated. Innovative strategies are needed to increase the use of effective antidepressive interventions in patients with cardiovascular disease.
KW  - depression
KW  - myocardial infarction
KW  - pharmacoepidemiology
KW  - stroke
KW  - treatment
Y1  - 2018
U6  - https://doi.org/10.1097/PSY.0000000000000632
SN  - 0033-3174
SN  - 1534-7796
VL  - 80
IS  - 8
SP  - 754
EP  - 763
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  -