TY - JOUR A1 - Zhang, Gong A1 - Hubalewska, Magdalena A1 - Ignatova, Zoya T1 - Transient ribosomal attenuation coordinates protein synthesis and co-translational folding N2 - Clustered codons that pair to low-abundance tRNA isoacceptors can form slow-translating regions in the mRNA and cause transient ribosomal arrest. We report that folding efficiency of the Escherichia coli multidomain protein Sufl can be severely perturbed by alterations in ribosome-mediated translational attenuation. Such alterations were achieved by global acceleration of the translation rate with tRNA excess in vitro or by synonymous substitutions to codons with highly abundant tRNAs both in vitro and in vivo. Conversely, the global slow-down of the translation rate modulated by low temperature suppresses the deleterious effect of the altered translational attenuation pattern. We propose that local discontinuous translation temporally separates the translation of segments of the peptide chain and actively coordinates their co-translational folding. Y1 - 2009 UR - http://www.nature.com/nsmb/ U6 - https://doi.org/10.1038/Nsmb.1554 SN - 1545-9985 ER - TY - JOUR A1 - Berger, Alfons A1 - Bousquet, Romain A1 - Engi, Martin A1 - Janots, Emilie A1 - Rubatto, Daniela A1 - Schmid, Stefan A1 - Wiederkehr, Michael T1 - Transport of heat and mass in a Barrovian belt : what do we know from nature? Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/00167037 U6 - https://doi.org/10.1016/j.gca.2009.05.002 SN - 0016-7037 ER - TY - JOUR A1 - Treydte, Anna C. A1 - Grant, Rina C. C. A1 - Jeltsch, Florian T1 - Tree size and herbivory determine below-canopy grass quality and species composition in savannahs N2 - Large single-standing trees are rapidly declining in savannahs, ecosystems supporting a high diversity of large herbivorous mammals. Savannah trees are important as they support both a unique flora and fauna. The herbaceous layer in particular responds to the structural and functional properties of a tree. As shrubland expands stem thickening occurs and large trees are replaced by smaller trees. Here we examine whether small trees are as effective in providing advantages for grasses growing beneath their crowns as large trees are. The role of herbivory in this positive tree- grass interaction is also investigated. We assessed soil and grass nutrient content, structural properties, and herbaceous species composition beneath trees of three size classes and under two grazing regimes in a South African savannah. We found that grass leaf content (N and P) beneath the crowns of particularly large (ca. 3.5 m) and very large trees (ca. 9 m) was as much as 40% greater than the same grass species not growing under a tree canopy, whereas nutrient contents of grasses did not differ beneath small trees (< 2.3 m). Moderate herbivory enhanced these effects slightly. Grass species composition differed beneath and beyond the tree canopy but not between tree size classes. As large trees significantly improve the grass nutrient quality for grazers in contrast to smaller trees, the decline of the former should be halted. The presence of trees further increases grass species diversity and patchiness by favouring shade- tolerant species. Both grazing wildlife and livestock will benefit from the presence of large trees because of their structural and functional importance for savannahs. Y1 - 2009 UR - http://www.springerlink.com/content/100125 U6 - https://doi.org/10.1007/s10531-009-9694-3 SN - 0960-3115 ER - TY - JOUR A1 - Trauth, Martin H. A1 - Larrasoaña, Juan C. A1 - Mudelsee, Manfred T1 - Trends, rhythms and events in plio-pleistocene African climate N2 - We analyzed published records of terrigenous dust flux from marine sediments off subtropical West Africa, the eastern Mediterranean Sea, and the Arabian Sea, and lake records from East Africa using statistical methods to detect trends, rhythms and events in Plio-Pleistocene African climate. The critical reassessment of the environmental significance of dust flux and lake records removes the apparent inconsistencies between marine vs. terrestrial records of African climate variability. Based on these results, major steps in mammalian and hominin evolution occurred during episodes of a wetter, but highly variable climate largely controlled by orbitally induced insolation changes in the low latitudes. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/02773791 U6 - https://doi.org/10.1016/j.quascirev.2008.11.003 SN - 0277-3791 ER - TY - JOUR A1 - Scheller, Frieder W. T1 - Tribute to Guenter Gauglitz (Editorial) Y1 - 2009 UR - http://www.springerlink.com/content/100417 U6 - https://doi.org/10.1007/s00216-008-2548-0 SN - 1618-2642 ER - TY - JOUR A1 - Kamjunke, Norbert A1 - Vogt, Bernhard A1 - Woelfl, Stefan T1 - Trophic interactions of the pelagic ciliate Stentor spp. in North Patagonian lakes N2 - The zooplankton of oligotrophic lakes in North Patagonia is often dominated by mixotrophic ciliates, particularly Stentor amethystinus and Stentor araucanus. Therefore, we tested whether Stentor spp. (i) is an important food for juvenile endemic (Cheirodon australe, Galaxias maculatus, Odontesthes mauleanum, Percichthys trucha) and introduced (Oncorhynchus mykiss) fish species, and (ii) represents a remarkable grazer of bacteria. Ingestion rates of fish estimated by disappearance of Stentor in feeding experiments ranged between 8 (G. maculatus) and 53 (C australe) ciliates per fish and day, and assimilation rates measured by using radioactively labelled Stentor ranged between 3 (P. trucha) and 52 (C australe) ciliates per fish and day. However, although we detected the consumption of Stentor by fish, the daily consumption amounted to at most 0.2% of the fish biomass which can not cover the energy requirement of the fish. Furthermore, the daily consumption was equivalent to a maximum of 1.6% of the Stentor standing stock so that fish predation does not seem to be an important mortality factor for the ciliates. The clearance rate of Stentor sp. on natural bacteria was on average 3.8 mu l cil(-1) h(-1). The daily ingestion (mean 3.9 ngC cil(-1) d(-1)) was about 3.5% of the individual biomass of Stentor sp. Therefore, bacteria ingestion might explain a ciliate growth rate of appr. 1% d(-1), which was about 17% of the photosynthesis of endosymbiotic algae. The maximum density of Stentor sp. in the take could ingest about 1 mu g C L-1 d(-1) bacteria which is only 3% of average bacterial production. Thus, grazing by Stentor sp. does not seem to be a main loss factor for the bacteria. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/00759511 U6 - https://doi.org/10.1016/j.limno.2008.08.001 SN - 0075-9511 ER - TY - JOUR A1 - Wischerhoff, Erik A1 - Glatzel, Stefan A1 - Uhlig, Katja A1 - Lankenau, Andreas A1 - Lutz, Jean-Francois A1 - Laschewsky, André T1 - Tuning the thickness of polymer brushes grafted from nonlinearly growing multilayer assemblies N2 - A new versatile method for tuning the thickness of surface-tethered polymer brushes is introduced. It is based on the combination of polyelectrolyte multilayer deposition and surface-initiated atom transfer radical polymerization. To control the thickness of the brushes, the nonlinear growth of certain polyelectrolyte multilayer systems is exploited. The method is demonstrated to work with different polyelectrolytes and different monomers. The relevance for applications is demonstrated by cell adhesion experiments oil grafted thermoresponsive polymer layers with varying thickness. Y1 - 2009 UR - http://pubs.acs.org/journal/langd5 U6 - https://doi.org/10.1021/La804197j SN - 0743-7463 ER - TY - JOUR A1 - Ostermeyer, Martin A1 - Korn, Dietmar A1 - Puhlmann, Dirk A1 - Henkel, Carsten A1 - Eisert, Jens T1 - Two-dimensional characterization of spatially entangled photon pairs N2 - We characterize the entanglement in position and momentum of photon pairs generated in type-II parametric down- conversion. Coincidence maps of the photon positions in the near-field and far-field planes are observed in two transverse dimensions using scanning fiber probes. We estimate the covariance matrix of an effective two-mode system and apply criteria for entanglement based on covariance matrices to certify space-momentum entanglement. The role of higher- order spatial modes for observing spatial entanglement between the two photons is discussed. Y1 - 2009 UR - http://www.informaworld.com/openurl?genre=journal&issn=0950-0340 U6 - https://doi.org/10.1080/09500340903359962 SN - 0950-0340 ER - TY - JOUR A1 - Hille, Carsten A1 - Lahn, Mattes A1 - Löhmannsröben, Hans-Gerd A1 - Dosche, Carsten T1 - Two-photon fluorescence lifetime imaging of intracellular chloride in cockroach salivary glands Y1 - 2009 UR - http://www.rsc.org/Publishing/Journals/pp/index.asp U6 - https://doi.org/10.1039/B813797H SN - 1474-905X ER - TY - JOUR A1 - Goelzer, Heiko A1 - Levermann, Anders A1 - Rahmstorf, Stefan T1 - Two-way coupling of an ENSO model to the global climate model CLIMBER-3 alpha N2 - We present a model study that investigates to what extent it is possible to introduce ENSO variability to an Earth system Model of Intermediate Complexity (EMIC). The Zebiak-Cane ENSO model is dynamically coupled to the EMIC CLIMBER-3 alpha, which by itself exhibits no interannual or multidecadal variability. ENSO variability is introduced to CLIMBER-3 alpha by adding ENSO-related sea surface temperature anomalies to the upper layers of the model ocean. For the other coupling direction, changes in the mean CLIMBER-3 alpha climate on decadal time scales are used to change the background state of the ENSO model, achieving a two-way coupling. We compare typical ENSO-related patterns of a fully coupled pre-industrial model run to reanalysis data and point out the possibilities and limitations of this model configuration. Although introduced ENSO-related SST anomalies and other related variables like the Southern Oscillation Index are well reproduced by the EMIC in the forcing domain, teleconnections to other regions are damped, especially in meridional direction. The reason for this limitation is the atmospheric model, which does not sufficiently resolve the necessary transport mechanisms. Despite this limitation the presented coupling method may still be a useful tool in combination with higher resolution atmospheric models as being in development for the successor model CLIMBER-3 and possibly other EMICs. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/14635003 U6 - https://doi.org/10.1016/j.ocemod.2009.03.004 SN - 1463-5003 ER - TY - JOUR A1 - Klamroth, Tillmann A1 - Nest, Mathias T1 - Ultrafast electronic excitations of small sodium clusters and the onset of electron thermalization N2 - In this paper we report simulations of the ultrafast laser excitation and relaxation of the correlated valence electrons of a Na-8 cluster. The aim is twofold: first, while the total energy stays constant when the exciting laser pulse is over, we observe that the entropy computed from the reduced one electron density matrix rises on a much longer time scale. We discuss whether this can be understood as the onset of the thermalization of a finite system. Second, we describe this process with eight different methods of wavefunction-based electronic structure theory, which have been adapted for an explicitly time-dependent description. Their respective advantages and limitations for the simulation of the excitation and subsequent relaxation are explained. Y1 - 2009 UR - http://pubs.rsc.org/en/Journals/JournalIssues/CP U6 - https://doi.org/10.1039/B813619j SN - 1463-9076 ER - TY - JOUR A1 - Woerner, Michael A1 - von Korff Schmising, Clemens A1 - Bargheer, Matias A1 - Zhavoronkov, Nickolai A1 - Vrejoiu, Ionela A1 - Hesse, Dietrich A1 - Alexe, Marin A1 - Elsaesser, Thomas T1 - Ultrafast structural dynamics of perovskite superlattices N2 - Femtosecond x-ray diffraction provides direct insight into the ultrafast reversible lattice dynamics of materials with a perovskite structure. Superlattice (SL) structures consisting of a sequence of nanometer-thick layer pairs allow for optically inducing a tailored stress profile that drives the lattice motions and for limiting the influence of strain propagation on the observed dynamics. We demonstrate this concept in a series of diffraction experiments with femtosecond time resolution, giving detailed information on the ultrafast lattice dynamics of ferroelectric and ferromagnetic superlattices. Anharmonically coupled lattice motions in a SrRuO3/PbZr0.2Ti0.8O3 (SRO/ PZT) SL lead to a switch-off of the electric polarizations on a time scale of the order of 1 ps. Ultrafast magnetostriction of photoexcited SRO layers is demonstrated in a SRO/SrTiO3 (STO) SL. Y1 - 2009 UR - http://www.springerlink.com/content/100501 U6 - https://doi.org/10.1007/s00339-009-5174-6 SN - 0947-8396 ER - TY - THES A1 - Radziuk, Darya V. T1 - Ultrasonic activation of nanocatalysts and formation of binary nanoparticles Y1 - 2009 CY - Potsdam ER - TY - JOUR A1 - Esser, Günter T1 - Umschriebene Entwicklungsstörungen Y1 - 2009 SN - 9788-3-642-01476-5 ER - TY - JOUR A1 - Hanke, Christine T1 - Umstrittenes Terrain : Perspektiven der Wissenschafts- und Technikforschung Y1 - 2009 ER - TY - JOUR A1 - Laggner, Benno T1 - UN-Politik der Schweiz: Handlungsmöglichkeiten eines Staates mittlerer Größe JF - Die Vereinten Nationen in den internationalen Beziehungen , 9. Potsdamer UNO-Konferenz am 28. Juni 2008 N2 - 1. Vorbemerkung 2. Geopolitische Rahmenbedingungen der aktuellen UN-Politik 3. Engagement der Schweiz in der UNO 4. Zwei konkrete Beispiele für schweizerische Initiativen im UN-Rahmen 5. Schlussbemerkung Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-101625 VL - 2009 IS - 8 SP - 15 EP - 22 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Pingel, Patrick A1 - Zen, Achmad A1 - Neher, Dieter A1 - Lieberwirth, Ingo A1 - Wegner, Gerhard A1 - Allard, Sybille A1 - Scherf, Ullrich T1 - Unexpectedly high field-effect mobility of a soluble, low molecular weight oligoquaterthiophene fraction with low polydispersity N2 - Layers made from soluble low molecular weight polythiophene PQT-12 with low polydispersity exhibit a highly ordered structure and charge-carrier mobilities of the order of 10(-3) cm(2)/(V s), which we attribute to its proximity to monodispersity. We propose that polydispersity is a decisive factor with regard to structure formation and transport properties of soluble low molecular weight polythiophenes. Y1 - 2009 UR - http://www.springerlink.com/content/100501 U6 - https://doi.org/10.1007/s00339-008-4994-0 SN - 0947-8396 ER - TY - BOOK A1 - Späth, Daniela T1 - Uni goes Facebook : Evaluatonsstudie zur Förderung von Kooperativen Lernprozessen mithilfe des Tools virtPresenter : eLearning UP 2009 : Sonderveranstaltung 2009-11-25 Y1 - 2009 UR - http://info.ub.uni-potsdam.de/multimedia/show_projekt.php?projekt_id=55 PB - Univ.-Bibl. CY - Potsdam ER - TY - JOUR A1 - Gerth, Sabrina A1 - Beim Graben, Peter T1 - Unifying syntactic theory and sentence processing difficulty through a connectionist minimalist parser N2 - Syntactic theory provides a rich array of representational assumptions about linguistic knowledge and processes. Such detailed and independently motivated constraints on grammatical knowledge ought to play a role in sentence comprehension. However most grammar-based explanations of processing difficulty in the literature have attempted to use grammatical representations and processes per se to explain processing difficulty. They did not take into account that the description of higher cognition in mind and brain encompasses two levels: on the one hand, at the macrolevel, symbolic computation is performed, and on the other hand, at the microlevel, computation is achieved through processes within a dynamical system. One critical question is therefore how linguistic theory and dynamical systems can be unified to provide an explanation for processing effects. Here, we present such a unification for a particular account to syntactic theory: namely a parser for Stabler's Minimalist Grammars, in the framework of Smolensky's Integrated Connectionist/Symbolic architectures. In simulations we demonstrate that the connectionist minimalist parser produces predictions which mirror global empirical findings from psycholinguistic research. Y1 - 2009 UR - http://www.springerlink.com/content/1871-4099 U6 - https://doi.org/10.1007/s11571-009-9093-1 SN - 1871-4080 ER - TY - BOOK A1 - Denecke, Klaus-Dieter A1 - Wismath, Shelly L. T1 - Universal Algebra and Coalgebra Y1 - 2009 SN - 978-981-283745-5 PB - World Scientific Publ. Co CY - Singapore ER - TY - THES A1 - Butkote, Runglawan T1 - Universal-algebraic and Semigroup-theoretical Properties of Boolean Operations Y1 - 2009 CY - Potsdam ER - TY - JOUR A1 - Weiss, Norman T1 - Universelle Menschenrechte in einer fragmentierten Welt Y1 - 2009 SN - 978-3- 7917-2214-6 ER - TY - JOUR A1 - Shkilnyy, Andriy A1 - Gräf, Ralph A1 - Hiebl, Bernhard A1 - Neffe, Axel T. A1 - Friedrich, Alwin A1 - Hartmann, Juergen A1 - Taubert, Andreas T1 - Unprecedented, low cytotoxicity of spongelike calcium phosphate/poly(ethylene imine) hydrogel composites N2 - Covalently crosslinked PEI hydrogels are efficient templates for calcium phosphate mineralization in SBF. In contrast to the PEI hydrogels, non-crosslinked PEI does not lead to calcium phosphate nucleation and growth in SBF. The precipitate is a mixture of brushite and hydroxyapatite. The PEI/calcium phosphate composite material exhibits a sponge like morphology and a chemical composition that is interesting for implants. Cytotoxicity tests using Dictyostelium discoideum amoebae show that both the non-mineralized and mineralized hydrogels have a very low cytotoxicity. This suggests that next generation PEI hydrogels, where also the degradation products are non-toxic, could be interesting for biomedical applications. Y1 - 2009 UR - http://www3.interscience.wiley.com/cgi-bin/jhome/77002860 U6 - https://doi.org/10.1002/mabi.200800266 SN - 1616-5187 ER - TY - JOUR A1 - de Frenne, Pieter A1 - Kolb, Annette A1 - Verheyen, Kris A1 - Brunet, Johanne A1 - Chabrerie, Olivier A1 - Decocq, Guillaume A1 - Diekmann, Martin A1 - Eriksson, Ove A1 - Heinken, Thilo A1 - Hermy, Martin A1 - Jõgar, Ülle A1 - Stanton, Sara A1 - Quataert, Paul A1 - Zindel, Renate A1 - Zobel, Martin A1 - Graae, Bente Jessen T1 - Unravelling the effects of temperature, latitude and local environment on the reproduction of forest herbs N2 - Aim To investigate the effect of temperature, latitude and local environment on the reproductive traits of widespread perennial forest herbs to better understand the potential impacts of rising temperatures on their population dynamics and colonization capacities. Location Six regions along a latitudinal gradient from France to Sweden. Methods Within each region, we collected data from three to five populations of up to six species. For each species, several variables were recorded in each region (temperature, latitude) and population (local abiotic and biotic environmental variables), and seed production and germination were estimated. Resource investment in reproduction (RIR) was quantified as seed number ¥ seed mass, while germinable seed output (GSO) was expressed as seed number ¥ germination percentage.We performed linear regression and mixed effect models to investigate the effects of temperature (growing degree hours), latitude and local abiotic and biotic environment on RIR and GSO. Results Temperature and latitude explained most of the variation in RIR and GSO for early flowering species with a northerly distribution range edge (Anemone nemorosa, Paris quadrifolia and Oxalis acetosella). Reproduction of the more southerly distributed species (Brachypodium sylvaticum, Circaea lutetiana and Primula elatior), in contrast, was independent of temperature/latitude. In the late summer species, B. sylvaticum and C. lutetiana, variation in RIR and GSO was best explained by local environmental variables, while none of the investigated variables appeared to be related to reproduction in P. elatior. Main conclusions We showed that reproduction of only two early flowering, northerly distributed species was related to temperature. This suggests that the potential reproductive response of forest herbs to climate warming partly depends on their phenology and distribution, but also that the response is to some extent species dependent. These findings should be taken into account when predictions about future shifts in distribution range are made. Y1 - 2009 UR - http://www3.interscience.wiley.com/journal/118545893/home U6 - https://doi.org/10.1111/j.1466-8238.2009.00487.x SN - 1466-822X ER - TY - JOUR A1 - Uba, Cornelius Eji A1 - Kley, Jonas A1 - Strecker, Manfred A1 - Schmitt, Axel K. T1 - Unsteady evolution of the Bolivian Subandean thrust belt : the role of enhanced erosion and clastic wedge progradation N2 - The Subandean fold and thrust belt of Bolivia constitutes the easternmost part of the Andean orogen that reflects thin-skinned shortening and eastward propagation of the Andean deformation front. The exact interplay of tectonics, climate, and erosion in the deposition of up to 7.5 km of late Cenozoic strata exposed in the Subandes remains unclear. To better constrain these relationships, we use four W-E industry seismic reflection profiles, eight new zircon U-Pb ages from Mio-Pliocene sedimentary strata, and cross-section balancing to evaluate the rates of thrust propagation, shortening, and deposition pinch-out migration. Eastward thrusting arrived in the Subandean belt at similar to 12.4 +/- 0.5 Ma and propagated rapidly toward the foreland unit approximately 6 Ma. This was followed by out-of- sequence deformation from ca. 4 to 2.1 Ma and by renewed eastward propagation thereafter. Our results show that the thrust-front propagation- and deposition pinch-out migration rates mimic the sediment accumulation rate. The rates of deposition pinchout migration and thrust propagation increased three- and two fold, respectively (8 mm/a; 3.3 mm/a) at 86 Ma. The three-fold increase in deposition pinch-out migration rate at this time is an indication of enhanced erosional efficiency in the hinterland, probably coupled with flexural rebound of the basin. Following the pulse of pinch-out migration, the Subandean belt witnessed rapid similar to 80 km eastward propagation of thrusting to the La Vertiente structure at 6 Ma. As there is no evidence for this event of thrust front migration being linked to an increase in shortening rate, the enhanced frontal accretion suggests a shift to supercritical wedge taper conditions. We propose that the supercritical state was due to a drop in basal strength, caused by sediment loading and pore fluid overpressure. This scenario implies that climate-controlled variation in erosional efficiency was the driver of late Miocene mass redistribution, which induced flexural rebound of the Subandean thrust belt, spreading of a large clastic wedge across the basin, and subsequent thrust-front propagation. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/0012821X U6 - https://doi.org/10.1016/j.epsl.2009.02.010 SN - 0012-821X ER - TY - JOUR A1 - Koehler, Andreas A1 - Ohrnberger, Matthias A1 - Scherbaum, Frank T1 - Unsupervised feature selection and general pattern discovery using Self-Organizing Maps for gaining insights into the nature of seismic wavefields N2 - This study presents an unsupervised feature selection and learning approach for the discovery and intuitive imaging of significant temporal patterns in seismic single-station or network recordings. For this purpose, the data are parametrized by real-valued feature vectors for short time windows using standard analysis tools for seismic data, such as frequency-wavenumber, polarization, and spectral analysis. We use Self-Organizing Maps (SOMs) for a data-driven feature selection, visualization and clustering procedure, which is in particular suitable for high-dimensional data sets. Our feature selection method is based on significance testing using the Wald-Wolfowitz runs test for-individual features and on correlation hunting with SOMs in feature subsets. Using synthetics composed of Rayleigh and Love waves and real-world data, we show the robustness and the improved discriminative power of that approach compared to feature subsets manually selected from individual wavefield parametrization methods. Furthermore, the capability of the clustering and visualization techniques to investigate the discrimination of wave phases is shown by means of synthetic waveforms and regional earthquake recordings. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/00983004 U6 - https://doi.org/10.1016/j.cageo.2009.02.004 SN - 0098-3004 ER - TY - THES A1 - Hartmann, Alexander T1 - Unterlassungsansprüche im Internet : Störerhaftung für nutzgenerierte Inhalte T2 - Information und Recht Y1 - 2009 SN - 978-3-406-59658-2 VL - 75 PB - Beck CY - München ER - TY - THES A1 - Dittmer, Mareike T1 - Unterricht, E-Mail und Internet in Kombination für das Lernen im Chemieunterricht Y1 - 2009 CY - Potsdam ER - TY - THES A1 - Schmidt, Antje T1 - Untersuchung des Recyclings Kaede-fusionierter Corticotropin-Releasing-Factor Rezeptoren Typ 1 T1 - Use of Kaede-Fusions to Visualize Recycling of the Corticotropin-Releasing Factor Receptor Type 1 N2 - Aktivierte G-Protein-gekoppelte Rezeptoren (GPCR) werden schnell desensitisiert, internalisiert und anschließend entweder lysosomal degradiert oder zur Plasmamembran (PM) recycelt. Zur Resensitisierung der Zellen tragen neben recycelten auch neusynthetisierte Rezeptoren bei. Die Überlagerung beider Prozesse erschwert die Untersuchung des Rezeptorrecyclings. In dieser Arbeit sollte mit Hilfe des photokonvertierbaren Fluoreszenzproteins Kaede eine Technik entwickelt werden, mit der es möglich ist Recycling- von Neusyntheseprozessen zu trennen und das Recycling von GPCR mikroskopisch in Echtzeit zu beobachten. Als Modellproteine wurden der Vasopressin-1a-Rezeptor V1aR (recycelnder Rezeptor), der Vasopressin-2-Rezeptor V2R (degradierter Rezeptor) und der Corticotropin-Releasing Factor-Rezeptor Typ 1 (CRF1R) verwendet, wobei bei Letzterem untersucht werden sollte, ob er nach Stimulation zur PM zurücktransportiert wird. Da Kaede als fluoreszierendes Protein mit den GPCR fusioniert wird, wurde zunächst überprüft, ob es die Eigenschaften der Rezeptoren verändert und generell für Transportstudien geeignet ist. Eventuell könnte die bereits publizierte Tetramerisierung von Kaede seine Anwendung verhindern oder erschweren. Mittels Fluoreszenz-Korrelationsspektroskopie konnte gezeigt werden, dass Kaede nicht tetramerisiert, wenn es an ein Membranprotein fusioniert ist. Außerdem konnte in in vitro- und Zellkulturexperimenten belegt werden, dass die native und die photokonvertierte Form von Kaede gleichermaßen stabil sind. Darüber hinaus zeigten Kaede-fusionierte GPCR sowohl in Kolokalisationsstudien als auch in Agonistbindungs- und Rezeptoraktivierungsexperimenten die gleichen Eigenschaften wie CFP- bzw. die unfusionierte Rezeptoren. Lediglich die Expression der Kaede-fusionierten Rezeptoren war geringer. Parallel wurde anhand der bereits publizierten Kaede-Struktur versucht, die Tetramerisierung des Proteins durch den Austausch interagierender Aminosäuren zu unterbinden. Die eingeführten Mutationen bewirkten aber eine Fehlfaltung des Proteins und damit den Verlust der Fluoreszenz. Da zuvor gezeigt werden konnte, dass Kaede-fusionierte Membranproteine nicht tetramerisieren und nicht die Eigenschaften der fusionierten Proteine verändern, war monomerisiertes Kaede zur Untersuchung des Rezeptorrecyclings nicht notwendig. Im zweiten Teil der Arbeit wurde mit Hilfe von Kaede-Fusionsproteinen und mikroskopischer Testsysteme das noch unbekannte Recyclingverhalten des CRF1R untersucht. Hierfür wurden die Kaede-fusionierten Rezeptoren in eukaryotischen Zellen exprimiert und mit Agonisten internalisiert. Die internalisierten Rezeptoren wurden in Endosomen selektiv mit UV-Strahlung photokonvertiert. Anschließend wurde der Transport der photokonvertierten Form verfolgt. Sowohl beim CRF1R als auch beim V1aR wurden Signale in der PM detektiert, beim V2R hingegen nicht. Dies zeigt, dass es sich beim CRF1R um einen recycelnden Rezeptor handelt. Die als Kontrolle eingesetzten Rezeptoren verhielten sich in diesem Experiment wie erwartet: Der V1aR wurde zur PM zurücktransportiert, der V2R nicht. Diese Ergebnisse konnten mit Hilfe biochemischer und durchflusscytometrischer Experimente bestätigt werden. Die Internalisierung des CRF1R verläuft Clathrin-vermittelt in Anwesenheit von β-Arrestin. Je nach Stabilität der β Arrestin-Interaktion unterscheidet man zwei Klassen von Rezeptoren: Klasse A-Rezeptoren interagieren transient mit β Arrestin und können recyceln. Im Gegensatz dazu gehen Klasse B-Rezeptoren eine stabile Interaktion mit β Arrestin ein und werden nach Internalisierung degradiert. In mikroskopischen Untersuchungen konnte für die aktivierten CRF1R und V1aR eine Rekrutierung von β Arrestin zur PM und eine transiente Interaktion mit β Arrestin gezeigt werden (Klasse A-Rezeptoren). Für den V2R wurde dagegen eine stabile Interaktion mit β Arrestin beobachtet (Klasse B-Rezeptor). Diese Daten stützen die Ergebnisse des Kaede-basierten Recyclingversuchs und zeigen, dass der CRF1R ein recycelnder Rezeptor ist. Ferner wurde untersucht, ob der CRF1R zu den schnell oder langsam recycelnden Rezeptoren zählt. Schnell recycelnde Rezeptoren werden direkt aus frühen Endosomen, langsam recycelnde hingegen über das Trans-Golgi-Netzwerk (TGN) bzw. über Recycling-Endosomen zur PM transportiert. Als Marker für das TGN oder die Recycling-Endosomen wurde Rab11 verwendet. In Kolokalisationsstudien konnte gezeigt werden, dass der CRF1R den langsam recycelnden Rezeptoren zugeordnet werden kann. Zusammenfassend konnte in dieser Arbeit belegt werden, dass Kaede als Fusionspartner für Membranproteine genutzt werden kann um deren Transport in Echtzeit zu studieren. Damit wurde erstmals eine mikroskopische Methode etabliert, die es erlaubt recycelnde von neusynthetisierten Rezeptoren zu unterscheiden. Mit Hilfe dieser Methode war es möglich zu zeigen, dass der CRF1R ein recycelnder Rezeptor ist. N2 - Upon ligand binding and receptor activation, G protein-coupled receptors (GPCR) are rapidly desensitized, internalized and subsequently degraded in lysosomes or recycled back to the plasma membrane. Resensitization of the cell is enabled by both recycling receptors and newly synthesized receptors. The overlap of recycling and synthesis processes largely complicates the study of GPCR recycling mechanisms. One aim of this thesis was to develop a new microscopic technique for real-time visualization of GPCR recycling using the photoconvertible Kaede protein allowing to differentiate newly synthesized from recycling receptors. As model proteins, the V1aR (recycling receptor), the V2R (degraded receptor) and the CRF1R were used. In the case of the CRF1R, it was unknown whether this receptor recycles to the plasma membrane following agonist-promoted internalization. The study of the CRF1R recycling behaviour was another objective of this work. As the Kaede protein is fused C-terminally to the GPCRs, an influence on the pharmacological and trafficking properties of the receptors must be excluded. The previously published tetramerization of Kaede, for example, might hinder or even prevent its usability. To assess for the applicability of Kaede, fluorescence correlation spectroscopy experiments were performed and it was demonstrated that Kaede fused to membrane proteins cannot form tetramers in contrast to the soluble form. In vitro studies and experiments in cell culture revealed that both the native and the photoconverted Kaede are equally stable. Moreover Kaede-fused GPCR displayed the same pharmacological and trafficking properties as the untagged or CFP-tagged receptors. Only the expression levels of the Kaede fusion proteins were reduced, yet this did not affect the microscopic experiments. In parallel to these experiments, the interacting amino acids of the tetrameric Kaede were substituted according to the previously published crystal structure of the protein. Unfortunately, these mutations induced protein misfolding thereby causing loss of fluorescence functions. However, since it could be shown that membrane protein-fused Kaede cannot tetramerize, the monomerized Kaede was no more essential for the microscopic study of receptor recycling. In the second part of this work, Kaede-fusions were used to study the recycling behaviour of the CRF1R and the V1aR and V2R control proteins by the novel real-time recycling assay at the laser scanning microscope. To this end, HEK 293 cells expressing the Kaede-fused receptors were treated with agonist to induce receptor internalization. Internalized receptors were selectively photoconverted in endosomes using UV-irradiation and the subcellular fate of the new fluorescence signals was studied. In the case of the CRF1R, signals of the photoconverted receptors could be detected in the plasma membrane indicating that the CRF1R belongs to the family of recycling receptors. The control receptors showed the expected results: The V1aR recycled back to the plasma membrane whereas the V2R did not. These results were confirmed with biochemical and flow cytometry measurements. The CRF1R internalizes in a clathrin-dependent way via the adaptor protein AP2, dynamin and β arrestin. Depending on the stability of the resulting receptor-β-arrestin-complex, two classes of receptors can be differentiated. Class A receptors are recycling receptors undergoing a more transient β-arrestin interaction. In contrast, class B receptors stably interact with β-arrestin and are degraded after internalization. In the case of the CRF1R and V1aR, microscopic analyzes demonstrated that β arrestin transiently interacts with the stimulated CRF1R and V1aR indicating again that these receptors are recycling GPCRs (class A receptors). The V2R, in contrast, revealed a stable interaction (class B receptor). Moreover, it was studied whether the CRF1R recycles rapidly or more slowly to the plasma membrane. Rapidly recycling receptors are recruited out of early endosomes whereas slowly recycling receptors pass the trans-golgi-network or recycling endosomes before reaching the cell surface. Rab11 colocalization studies demonstrated that the CRF1R belongs to the family of slowly recycling receptors. In conclusion, a novel microscopic technique was established allowing to study GPCR recycling in real-time and to differentiate recycling and synthesis processes. Moreover, it was shown that the CRF1R belongs to the family of recycling receptors. The Kaede technique seems to be very well suited to study membrane protein trafficking in general. KW - Corticotropin-Releasing Factor Rezeptor Typ 1 KW - Recycling KW - GPCR KW - Kaede KW - Corticotropin-Releasing Factor Receptor Type 1 KW - Recycling KW - GPCR KW - Kaede Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-34902 ER - TY - THES A1 - Apel, Wiebke T1 - Untersuchung und Veränderung der Genexpression und Proteinstabilität in Plastiden höherer Pflanzen Y1 - 2009 CY - Potsdam ER - TY - BOOK A1 - Brechenmacher, Thomas T1 - Unveröffentliche Dokumente aus dem Nachlaß des Ministerialdirektors Rudolf Buttmann zur Geschichte des Reichskonkordates (1933-1935) Y1 - 2009 SN - 978-3-506-76465-2 ER - TY - JOUR A1 - Oberauer, Klaus A1 - Vockenberg, Kerstin T1 - Updating of working memory : lingering bindings N2 - Three experiments investigated proactive interference and proactive facilitation in a memory-updating paradigm. Participants remembered several letters or spatial patterns, distinguished by their spatial positions, and updated them by new stimuli up to 20 times per trial. Self-paced updating times were shorter when an item previously remembered and then replaced reappeared in the same location than when it reappeared in a different location. This effect demonstrates residual memory for no-longer-relevant bindings of items to locations. The effect increased with the number of items to be remembered. With one exception, updating times did not increase, and recall of final values did not decrease, over successive updating steps, thus providing little evidence for proactive interference building up cumulatively. Y1 - 2009 UR - http://www.informaworld.com/openurl?genre=journal&issn=1747-0218 U6 - https://doi.org/10.1080/17470210802372912 SN - 1747-0218 ER - TY - THES A1 - Ulrich, Jan Nicolaus T1 - Urherrecht und Satellitenrundfunk : Kollisionsrecht und materielles Recht Y1 - 2009 SN - 978-3-8305-1693-4 PB - BWV CY - Berlin ER - TY - JOUR A1 - Nagl, Britta A1 - Loui, Andrea A1 - Raila, Jens A1 - Felderhoff-Mueser, Ursula A1 - Obladen, Michael A1 - Schweigert, Florian J. T1 - Urinary vitamin A excretion in very low birth weight infants N2 - Vitamin A (VA) deficiency in very low birth weight (VLBW) infants is associated with an increased risk for disorders related to kidney and lung maturation and function. VA losses through increased urinary retinol (ROH) excretion might contribute to this deficiency risk. The mechanism accounting for ROH loss in the urine has not yet been clarified. The aim of this study was to assess the excretion of ROH, retinol-binding protein 4 (RBP4) and transthyretin (TTR) in urine from VLBW infants in comparison with that in term infants in relation to kidney function. Urine specimens were collected from 15 VLBW infants (birth weight < 1,500 g) as well as from 20 term infants during the first 2 days after birth. ROH in urine was detectable in 14 of the 15 VLBW infants at a median concentration of 234 nmol/g creatinine. In the group of term infants, 17 of the 20 excreted ROH, but at an approximately five-times lower concentration (P<0.001). Excretion of RBP4 and TTR was also much higher in VLBW infants (both P<0.001). The urinary ROH excretion in VLBW infants may be related to the impaired tubular handling of its carrier proteins RBP4 and TTR. Thus, ROH excretion might contribute to an increased risk of VA deficiency, especially in VLBW infants. Y1 - 2009 UR - http://www.springerlink.com/content/100382 U6 - https://doi.org/10.1007/s00467-008-0965-0 SN - 0931-041X ER - TY - JOUR A1 - de Libero, Loretana T1 - Usbekistan in der Antike Y1 - 2009 ER - TY - JOUR A1 - Gebhardt, Constance A1 - Hirschberger, Johannes A1 - Rau, Stefanie A1 - Arndt, Gisela A1 - Krainer, Karen A1 - Schweigert, Florian J. A1 - Brunnberg, Leo A1 - Kaspers, Bernd A1 - Kohn, Barbara T1 - Use of C-reactive protein to predict outcome in dogs with systemic inflammatory response syndrome or sepsis N2 - Background There is a high mortality rate in patients with systemic inflammatory response syndrome (SIRS) or sepsis. Therefore, an early diagnosis and prognostic assessment is important for optimal therapeutic intervention. The objective of the study was to evaluate if baseline values and changes in serum C-reactive protein (CRP) might predict survival in dogs with SIRS and sepsis. Design Prospective study; July 2004 to July 2005. Setting Small Animal Clinic, Berlin, Clinic of Small Animal Medicine, Munich. Animals Sixty-one dogs. Measurements and Main Results For the CRP analysis blood was drawn on day 0, 1, and 2; CRP was measured using a commercial ELISA test kit. Thirteen dogs suffered from nonseptic SIRS and 48 dogs from sepsis. The 14-day survival rate was 61% (69% nonseptic SIRS, 58% sepsis). Serum CRP was higher in sick dogs compared with controls (P < 0.001). Over the 3-day period surviving dogs (n=31) displayed a significantly greater decrease in CRP than nonsurvivors (n=10) (P=0.001). No correlation was found between the initial CRP concentrations and the survival rate. The changes in CRP corresponded to the survival rate (P=0.01). Conclusion There was no significant relationship between the survival rate in dogs with nonseptic SIRS or sepsis and the initial serum CRP concentrations. There was a correlation between decreasing CRP concentrations and recovery from disease. However, the changes in CRP concentrations over a 3-day period correctly predicted survival in 94% of dogs and death in 30% of the dogs (false positive rate 22%). Y1 - 2009 UR - http://www3.interscience.wiley.com/cgi-bin/issn?DESCRIPTOR=PRINTISSN&VALUE=1479-3261 U6 - https://doi.org/10.1111/j.1476-4431.2009.00462.x SN - 1479-3261 ER - TY - GEN A1 - Blume, Theresa A1 - Zehe, Erwin A1 - Bronstert, Axel T1 - Use of soil moisture dynamics and patterns at different spatio-temporal scales for the investigation of subsurface flow processes N2 - Spatial patterns as well as temporal dynamics of soil moisture have a major influence on runoff generation. The investigation of these dynamics and patterns can thus yield valuable information on hydrological processes, especially in data scarce or previously ungauged catchments. The combination of spatially scarce but temporally high resolution soil moisture profiles with episodic and thus temporally scarce moisture profiles at additional locations provides information on spatial as well as temporal patterns of soil moisture at the hillslope transect scale. This approach is better suited to difficult terrain (dense forest, steep slopes) than geophysical techniques and at the same time less cost-intensive than a high resolution grid of continuously measuring sensors. Rainfall simulation experiments with dye tracers while continuously monitoring soil moisture response allows for visualization of flow processes in the unsaturated zone at these locations. Data was analyzed at different spacio-temporal scales using various graphical methods, such as space-time colour maps (for the event and plot scale) and binary indicator maps (for the long-term and hillslope scale). Annual dynamics of soil moisture and decimeterscale variability were also investigated. The proposed approach proved to be successful in the investigation of flow processes in the unsaturated zone and showed the importance of preferential flow in the Malalcahuello Catchment, a datascarce catchment in the Andes of Southern Chile. Fast response times of stream flow indicate that preferential flow observed at the plot scale might also be of importance at the hillslope or catchment scale. Flow patterns were highly variable in space but persistent in time. The most likely explanation for preferential flow in this catchment is a combination of hydrophobicity, small scale heterogeneity in rainfall due to redistribution in the canopy and strong gradients in unsaturated conductivities leading to self-reinforcing flow paths. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 125 KW - Repellent sandy soil KW - Poorly gauged catchment KW - Volcanic ash soils KW - Water repellency KW - Preferential flow Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-44924 ER - TY - JOUR A1 - Tittel, Joerg A1 - Wiehle, Ines A1 - Wannicke, Nicola A1 - Kampe, Heike A1 - Poerschmann, Juergen A1 - Meier, Jutta A1 - Kamjunke, Norbert T1 - Utilisation of terrestrial carbon by osmotrophic algae N2 - Terrestrial-derived dissolved organic carbon (DOC) contributes significantly to the energetic basis of many aquatic food webs. Although heterotrophic bacteria are generally considered to be the sole consumers of DOC, algae and cyanobacteria of various taxonomic groups are also capable of exploiting this resource. We tested the hypothesis that algae can utilise DOC in the presence of bacteria if organic resources are supplied in intervals by photolysis of recalcitrant DOC. In short-term uptake experiments, we changed irradiation in the range of minutes. As model substrates, polymers of radiolabelled coumaric acid (PCA) were used, which during photolysis are known to release aromatic compounds comparable to terrestrial-derived and refractory DOC. Three cultured freshwater algae readily assimilated PCA photoproducts equivalent to a biomass-specific uptake of 5-60% of the bacterial competitors present. Algal substrate acquisition did not depend on whether PCA was photolysed continuously or in intervals. However, the data show that photoproducts of terrestrial DOC can be a significant resource for osmotrophic algae. In long-term growth experiments, interval light was applied one hour per day. We allowed cultured Chlamydomonas to compete for ambient DOC of low concentration. We found higher abundances of Chlamydomonas when cultures were irradiated intermittently rather than continuously. These data suggest that photolysis of DOC supports algal heterotrophy, and potentially facilitates growth, when light fluctuations are large, as during the diurnal light cycle. We concluded that osmotrophic algae can efficiently convert terrestrial carbon into the biomass of larger organisms of aquatic food webs. Y1 - 2009 UR - http://www.springerlink.com/content/101191 U6 - https://doi.org/10.1007/s00027-008-8121-2 SN - 1015-1621 ER - TY - JOUR A1 - Schröder, Miriam T1 - Utilizing the clean development mechanism for the deployment of renewable energies in China N2 - This article discusses how much the clean development mechanism (CDM) can contribute to the deployment of renewable energies (RE) in China. While there are at least two general barriers to utilizing CDM finance for RE deployment - namely high project costs and the proof of additionality - this article argues that an appropriate national regulation Can lead RE technologies to a stage of commercialisation at which CDM financing can become crucial. For an assessment of the current policy mix in place in China for the deployment of renewable energies, the article compares the national Chinese regulations for renewable energies and China's specific CDM rules for their impact: where do general and CDM-specific regulations for the promotion of renewable energies provide synergies, where does the policy- making on these two levels collide? Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/03062619 U6 - https://doi.org/10.1016/j.apenergy.2008.04.019 SN - 0306-2619 ER - TY - BOOK A1 - Kimminich, Eva T1 - Utopien, Jugendkulturen und Lebenswirklichkeiten : ästhetische Praxis als politisches Handeln T3 - Welt - Körper - Sprache Y1 - 2009 SN - 978-3-631-59938-9 VL - 7 PB - Lang CY - Frankfurt am Main ER - TY - GEN A1 - Voss, Martin A1 - Blenau, Wolfgang A1 - Walz, Bernd A1 - Baumann, Otto T1 - V-ATPase deactivation in blowfly salivary glands is mediated by protein phosphatase 2C N2 - The activity of vacuolar H+-ATPase (V-ATPase) in the apical membrane of blowfly (Calliphora vicina) salivary glands is regulated by the neurohormone serotonin (5-HT). 5-HT induces, via protein kinase A, the phosphorylation of V-ATPase subunit C and the assembly of V-ATPase holoenzymes. The protein phosphatase responsible for the dephosphorylation of subunit C and V-ATPase inactivation is not as yet known. We show here that inhibitors of protein phosphatases PP1 and PP2A (tautomycin, ocadaic acid) and PP2B (cyclosporin A, FK-506) do not prevent V-ATPase deactivation and dephosphorylation of subunit C. A decrease in the intracellular Mg2+ level caused by loading secretory cells with EDTA-AM leads to the activation of proton pumping in the absence of 5-HT, prolongs the 5-HT-induced response in proton pumping, and inhibits the dephosphorylation of subunit C. Thus, the deactivation of V-ATPase is most probably mediated by a protein phosphatase that is insensitive to okadaic acid and that requires Mg2+, namely, a member of the PP2C protein family. By molecular biological techniques, we demonstrate the expression of at least two PP2C protein family members in blowfly salivary glands. © 2009 Wiley Periodicals, Inc. KW - vacuolar H+-ATPase KW - assembly KW - regulation KW - protein phosphatise KW - dephosphorylation Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-44360 ER - TY - JOUR A1 - de Libero, Loretana T1 - Vae victis! Das Schicksal der Besiegten in der römischen Antike Y1 - 2009 SN - 978-3-8062-2279-1 ER - TY - JOUR A1 - Stein, Ruediger A1 - Hefter, Jens A1 - Gruetzner, Jens A1 - Voelker, Antje A1 - Naafs, B. David A. T1 - Variability of surface water characteristics and Heinrich-like events in the Pleistocene midlatitude North Atlantic Ocean: Biomarker and XRD records from IODP Site U1313 (MIS 16-9) N2 - A reconstruction of Milankovitch to millennial-scale variability of sea surface temperature (SST) and sea surface productivity in the Pleistocene midlatitude North Atlantic Ocean (marine isotope stage (MIS) 16-9) and its relationship to ice sheet instability was carried out on sediments from Integrated Ocean Drilling Program (IODP) Site U1313. This reconstruction is based on alkenone and n-alkane concentrations, U-37(K)' index, total organic carbon (TOC) and carbonate contents, X-ray diffraction data, magnetic susceptibility, and accumulation rates. Increased input of ice-rafted debris occurred during MIS 16, 12, and 10, characterized by high concentrations of dolomite, quartz, and feldspars and elevated accumulation rates of terrigenous matter. Minimum input values of terrigenous matter, on the other hand, were determined for MIS 13 and 11. Peak values of dolomite, coinciding with quartz, plagioclase, and kalifeldspar peaks and maxima in long-chain n-alkanes indicative for land plants, are interpreted as Heinrich-like events related to sudden instability of the Laurentide Ice Sheet during early and late (deglacial) phases of the glacials. The coincidence of increased TOC values with elevated absolute concentrations of alkenones suggests increased glacial productivity, probably due to a more southern position of the Polar Front. Alkenone-based SST reached absolute maxima of about 19 degrees C during MIS 11.3 and absolute minima of <10 degrees C during MIS 12 and 10. Within MIS 11, prominent cooling events (MIS 11.22 and 11.24) occurred. The absolute SST minima recorded directly before and after the glacial maxima MIS 10.2 and 12.2 are related to Heinrich-like event meltwater pulses, as supported by the coincidence of SST minima and maxima in C-37:4 alkenones and dolomite. These sudden meltwater pulses, especially during terminations IV and V, probably caused a collapse of phytoplankton productivity as indicated by the distinct drop in alkenone concentrations. Ice sheet disintegration and subsequent surges and outbursts of icebergs and meltwater discharge may have been triggered by increased insolation in the northern high latitudes. Y1 - 2009 UR - http://www.agu.org/journals/pa/ U6 - https://doi.org/10.1029/2008pa001639 SN - 0883-8305 ER - TY - JOUR A1 - Riesch, Rüdiger A1 - Duwe, Virginia A1 - Herrmann, Nina A1 - Padur, Lisa A1 - Ramm, Annemarie A1 - Scharnweber, Inga Kristin A1 - Schulte, Matthias A1 - Schulz-Mirbach, Tanja A1 - Ziege, Madlen A1 - Plath, Martin T1 - Variation along the shy-bold continuum in extremophile fishes (Poecilia mexicana, Poecilia sulphuraria) N2 - One potential trade-off that bold individuals face is between increased predation risks and gains in resources. Individuals experiencing high predation and hungry individuals (or individuals with low body condition) are predicted to show increased boldness. We examined one behavioral trait previously reported to be associated with boldness (the time individual fish needed to emerge from shelter) in various populations of mollies (Poecilia spp.). Our study system included several southern Mexican surface streams with high piscine predation and high food availability, sulfidic surface streams with high avian predation, in which the inhabiting fish show reduced body condition, and a sulfidic cave, where predation and body condition are low. Our comparison revealed very short times to emerge from the start box in populations from non-sulfidic streams. In sulfidic habitats (whether surface or cave), it took individual Poecilia mexicana considerably longer to emerge from the start box, and the same difference was also found in an independent comparison between P. mexicana and the closely related, highly sulfide-adapted Poecilia sulphuraria. Fish reared under common garden conditions (in the absence of predators and hydrogen sulfide) showed intermediate boldness scores to the extremes observed in the field. Our data thus indicate that (a) boldness is shaped by environmental conditions/ experiential effects, but is not heritable, (b) predation affects boldness in the predicted direction, but (c) low body condition leads to reduced boldness. Extremophile Poecilia spp. spend most of their time surfacing to survive under sulfidic and hypoxic conditions, which exposes them to increased levels of predations, but the fish forage on the bottom. Hence, in this system, increased boldness does not increase foraging success. We argue that energy limitation favors reducing energetically costly behaviors, and exploring novel environments may be just one of them. Y1 - 2009 UR - http://www.springerlink.com/content/100464 U6 - https://doi.org/10.1007/s00265-009-0780-z SN - 0340-5443 ER - TY - BOOK ED - Kügler, Frank ED - Féry, Caroline ED - van de Vijver, Ruben T1 - Variation and gradience in phonetics and phonology T3 - Phonology and Phonetics Y1 - 2009 SN - 978-3-11-021931-9 VL - 14 PB - Mouton de Gruyter CY - Berlin ER - TY - JOUR A1 - Fuhr, Harald A1 - Lederer, Markus T1 - Varieties of carbon governance in newly industrializing Y1 - 2009 SN - 1070-4965 ER - TY - BOOK A1 - Höppner, Dörte A1 - Wohlrath, Christin T1 - Venture Capital als Finanzierungsalternative für Unternehmensgründungen Y1 - 2009 SN - 978-3-89936-799-7 ER - TY - BOOK A1 - Andrae, Marianne A1 - Ebert, Johannes A1 - Garbe-von Kuczkowski, Angela A1 - Garbe, Roland A1 - Grabow, Christian A1 - Klees-Wambach, Marie-Luise A1 - Kofler, Rolf A1 - Mittmann, Michael A1 - Nickel, Michael A1 - Nöthen, Thomas A1 - Schrader-Kroschewski, Karen A1 - Schramm, Barbara A1 - Ulrich, Christoph ED - Garbe, Roland T1 - Verfahren in Familiensachen : FamFG ; ZPO ; BGB T3 - Nomos ProzessHandbuch Y1 - 2009 SN - 978-3-8329-3973-1 PB - Nomos; Beck-Online CY - Baden-Baden; München ER - TY - BOOK A1 - Bahro, Berno A1 - Braun, Jutta A1 - Teichler, Hans Joachim T1 - Vergessene Rekorde : jüdische Leichtathletinnen vor und nach 1933 Y1 - 2009 SN - 978-3-86650-038-9 PB - vbb Verl. für Berlin-Brandenburg CY - Berlin ER - TY - JOUR A1 - Sebti, Samira A1 - Saddiqi, Omar A1 - El Haimer, Fatima Zahra A1 - Michard, André A1 - Ruiz, Geoffrey A1 - Bousquet, Romain A1 - Baidder, Lahssen A1 - de Lamotte, Dominique Frizon T1 - Vertical movements at the fringe of the West African Craton : first zircon fission track datings from the Anti- Atlas Precambrian basement, Morocco N2 - The post-Variscan uplift of the western Anti-Atlas Precambrian core is studied by zircon fission track (ZFT) analysis of ten samples of granites and schists from the Kerdous and Ifni inliers. All samples yield Carboniferous ZFT ages ranging from 358 +/- 31 Ma to 319 +/- 32 Ma, with nine dates younger than 338 +/- 35 Ma. The weighted mean age calculated for these nine samples is 328 +/- 30 Ma. These results compare with the available K-Ar datings of white mica and biotite from the same rocks or from the overlying Ediacaran-Cambrian low-grade metasediments. The fact that different systems with distinct closure temperatures yield similar ages suggests the occurrence of a short Carboniferous thermal event followed by rapid cooling. Consistent with the regional geological framework, the thermal event is assigned to the Variscan folding, being followed by rapid exhumation and cooling related to the post-folding erosion. To cite this article: S. Sebti et aL, C. R. Geoscience 341 (2009). Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/16310713 U6 - https://doi.org/10.1016/j.crte.2008.11.006 SN - 1631-0713 ER - TY - BOOK A1 - Bogumil, Jörg A1 - Jann, Werner ED - Benz, Arthur ED - Lütz, Susanne ED - Simonis, Georg ED - Benz, Arthur ED - Döhler, Marian ED - Lauth, Hans-Joachim T1 - Verwaltung und Verwaltungswissenschaft in Deutschland : Einführung in die Verwaltungswissenschaft T3 - Grundwissen Politik Y1 - 2009 SN - 978-3-531-16172-3 U6 - https://doi.org/10.1007/978-3-531-91341-4 VL - 36 PB - VS Verl. für Sozialwiss CY - Wiesbaden ER - TY - JOUR A1 - Prengel, Annedore T1 - Vielfalt Y1 - 2009 SN - 978-3-17-019631-5 ER - TY - THES A1 - Schmallowsky, Antje T1 - Visualisierung dynamischer Raumphänomene in Geoinformationssystemen T1 - Visualization of dynamic spatial phenomena in geographic information systems N2 - Die visuelle Kommunikation ist eine effiziente Methode, um dynamische Phänomene zu beschreiben. Informationsobjekte präzise wahrzunehmen, einen schnellen Zugriff auf strukturierte und relevante Informationen zu ermöglichen, erfordert konsistente und nach dem formalen Minimalprinzip konzipierte Analyse- und Darstellungsmethoden. Dynamische Raumphänomene in Geoinformationssystemen können durch den Mangel an konzeptionellen Optimierungsanpassungen aufgrund ihrer statischen Systemstruktur nur bedingt die Informationen von Raum und Zeit modellieren. Die Forschung in dieser Arbeit ist daher auf drei interdisziplinäre Ansätze fokussiert. Der erste Ansatz stellt eine echtzeitnahe Datenerfassung dar, die in Geodatenbanken zeitorientiert verwaltet wird. Der zweite Ansatz betrachtet Analyse- und Simulationsmethoden, die das dynamische Verhalten analysieren und prognostizieren. Der dritte Ansatz konzipiert Visualisierungsmethoden, die insbesondere dynamische Prozesse abbilden. Die Symbolisierung der Prozesse passt sich bedarfsweise in Abhängigkeit des Prozessverlaufes und der Interaktion zwischen Datenbanken und Simulationsmodellen den verschiedenen Entwicklungsphasen an. Dynamische Aspekte können so mit Hilfe bewährter Funktionen aus der GI-Science zeitnah mit modularen Werkzeugen entwickelt und visualisiert werden. Die Analyse-, Verschneidungs- und Datenverwaltungsfunktionen sollen hierbei als Nutzungs- und Auswertungspotential alternativ zu Methoden statischer Karten dienen. Bedeutend für die zeitliche Komponente ist das Verknüpfen neuer Technologien, z. B. die Simulation und Animation, basierend auf einer strukturierten Zeitdatenbank in Verbindung mit statistischen Verfahren. Methodisch werden Modellansätze und Visualisierungstechniken entwickelt, die auf den Bereich Verkehr transferiert werden. Verkehrsdynamische Phänomene, die nicht zusammenhängend und umfassend darstellbar sind, werden modular in einer serviceorientierten Architektur separiert, um sie in verschiedenen Ebenen räumlich und zeitlich visuell zu präsentieren. Entwicklungen der Vergangenheit und Prognosen der Zukunft werden über verschiedene Berechnungsmethoden modelliert und visuell analysiert. Die Verknüpfung einer Mikrosimulation (Abbildung einzelner Fahrzeuge) mit einer netzgesteuerten Makrosimulation (Abbildung eines gesamten Straßennetzes) ermöglicht eine maßstabsunabhängige Simulation und Visualisierung des Mobilitätsverhaltens ohne zeitaufwendige Bewertungsmodellberechnungen. Zukünftig wird die visuelle Analyse raum-zeitlicher Veränderungen für planerische Entscheidungen ein effizientes Mittel sein, um Informationen übergreifend verfügbar, klar strukturiert und zweckorientiert zur Verfügung zu stellen. Der Mehrwert durch visuelle Geoanalysen, die modular in einem System integriert sind, ist das flexible Auswerten von Messdaten nach zeitlichen und räumlichen Merkmalen. N2 - Visual communication is an efficient method to describe dynamic phenomena. Perceiving information objects precisely and facilitating quick access to structured and relevant information requires consistent analysis and presentation methods conceived according to the formal minimisation principle. Because of the lack of conceptual optimisation adaptations due to their static system structure, dynamic space phenomena in geoinformation systems can only model the information of time and space conditionally. This is why research in this paper focuses on three interdisciplinary approaches. The first approach represents data collection close to real-time which is administered in geodatabases in a time-oriented manner. The second approach looks at analysis and simulation methods that analyse and forecast dynamic behaviour. The third approach conceives visualisation methods that model dynamic processes in particular. Where required, the symbolising of processes adapts to the various development phases depending on the process flow and the interaction between databases and simulation models. This allows dynamic aspects to be developed and visualised in a timely manner using modular tools with the help of proven geoscience functions. The analysis, intersection and data administration functions are intended to serve as utilisation and analysis potential as an alternative to static chart methods. For the time component, linking new technologies such as simulation and animation is significant based on a structured time database in connection with statistical methods. Modelling approaches and visualisation techniques are methodically developed and transferred to the traffic field. Dynamic traffic phenomena that cannot be modelled cohesively and comprehensively are separated into a service-oriented modular architecture in order to present them visually on different levels of space and time. Past developments and forecasts are modelled and visually analysed using various calculation methods. Linking a micro-simulation (modelling individual vehicles) to a network-controlled macro-simulation (modelling an entire road network) makes it possible to simulate and visualise mobility behaviour regardless of scale without time-consuming analysis model calculations. In the future, the visual analysis of space-time changes for planning decisions will be an efficient tool in order to make comprehensive, clearly structured and appropriate information available. The flexible analysis of measurement data according to time and space criteria represents the added value of visual geoanalysis integrated into a system with a modular structure. KW - Visualisierung KW - dynamischer Raumphänomene KW - GIS KW - Dynamik KW - Kartographie KW - Kommunikation KW - Geodaten KW - Zeit GIS KW - temporale Symbolik KW - Visualization KW - dynamic spatial phenomena KW - GIS KW - dynamics KW - cartography KW - communication KW - spatial data KW - geosience KW - temporale Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-41262 ER - TY - JOUR A1 - Kleinpeter, Erich A1 - Szatmári, István A1 - Lázár, László A1 - Koch, Andreas A1 - Heydenreich, Matthias A1 - Fulop, Ferenc T1 - Visualization and quantification of anisotropic effects on the 1H NMR spectra of 1,3-oxazino[4,3- alpha]isoquinolines - indirect estimates of steric compression N2 - The anisotropic effects of the phenyl, alpha- and beta-naphthyl moieties in four series of 1,3-oxazino[4,3- a]isoquinolines on the H-1 chemical shifts of the isoquinoline protons were calculated by employing the Nucleus Independent Chemical Shift (NICS) concept and Visualized as anisotropic cones by a through-space NMR shielding grid. The signs and extents of these spatial effects on the H-1 chemical shifts of the isoquinoline protons were compared with the experimental H-1 NMR spectra. The differences between the experimental delta (H-1)/ppm values and the calculated anisotropic effects of the aromatic moieties are discussed in terms of the steric compression that occurs in the Compounds studied. Y1 - 2009 U6 - https://doi.org/10.1016/j.tet.2009.07.038 SN - 0040-4020 ER - TY - JOUR A1 - Kleinpeter, Erich A1 - Koch, Andreas T1 - Visualization of homoaromaticity in cations, neutral molecules and anions by spatial magnetic properties (through space NMR shieldings) - an 1H/13C NMR chemical shift study N2 - Prototypes for homoaromaticity in cations, neutral molecules, and anions are theoretically studied at the MP2 level of theory. For the global minimum structures on the potential energy surface both 1H/13C chemical shifts and spatial magnetic properties as through space NMR shieldings (TSNMRS) were calculated by the GIAO perturbation method. The TSNMRS are visualized as iso-chemical-shielding surfaces (ICSS) of different sign and size. Coincident experimental and computed 1H/13C chemical shifts afforded the possibility to decide from the TSNMRSs at hand on both the existence and the size of homoaromaticity in the molecules studied. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/00404020 U6 - https://doi.org/10.1016/j.tet.2009.04.063 SN - 0040-4020 ER - TY - THES A1 - Nell, Sandra T1 - Vitamin E und der vesikuläre Transport : Untersuchungen zu den genregulatorischen Funktionen von Vitamin E mittels Microarray- und real time PCR-Analysen in der Maus und funktionellen in vitro Assays in RBL-2H3 Zellen T1 - Vitamin E and the vesicular transport : examination of the generegulatory functions of vitamin E using microarrays and real time PCR analyses in the mouse and functional in vitro assays in RBL-2H3 cells N2 - Vitamin E wird immer noch als das wichtigste lipophile Antioxidanz in biologischen Membranen betrachtet. In den letzten Jahren hat sich jedoch der Schwerpunkt der Vitamin E-Forschung hin zu den nicht-antioxidativen Funktionen verlagert. Besonderes Interesse gilt dabei dem α-Tocopherol, der häufigsten Vitamin E-Form im Gewebe von Säugetieren, und seiner Rolle bei der Regulation der Genexpression. Das Ziel dieser Dissertation war die Untersuchung der genregulatorischen Funktionen von α-Tocoperol und die Identifizierung α-Tocopherol-sensitiver Gene in vivo. Zu diesem Zweck wurden Mäuse mit verschiedenen Mengen α-Tocopherol gefüttert. Die Analyse der hepatischen Genexpression mit Hilfe von DNA-Microarrays identifizierte 387 α-Tocopherol-sensitive Gene. Funktionelle Clusteranalysen der differentiell exprimierten Gene zeigten einen Einfluss von α-Tocooherol auf zelluläre Transportprozesse. Besonders solche Gene, die an vesikulären Transportvorgängen beteiligt sind, wurden größtenteils durch α-Tocopherol hochreguliert. Für Syntaxin 1C, Vesicle-associated membrane protein 1, N-ethylmaleimide-sensitive factor and Syntaxin binding protein 1 konnte eine erhöhte Expression mittels real time PCR bestätigt werden. Ein funktioneller Einfluss von α-Tocopherol auf vesikuläre Transportprozesse konnte mit Hilfe des in vitro β-Hexosaminidase Assays in der sekretorischen Mastzelllinie RBL-2H3 gezeigt werden. Die Inkubation der Zellen mit α-Tocopherol resultierte in einer konzentrationsabhängigen Erhöhung der PMA/Ionomycin-stimulierten Sekretion der β-Hexosaminidase. Eine erhöhte Expression ausgewählter Gene, die an der Degranulation beteiligt sind, konnte nicht beobachtet werden. Damit schien ein direkter genregulatorischer Effekt von α-Tocopherol eher unwahrscheinlich. Da eine erhöhte Sekretion auch mit β-Tocopherol aber nicht mit Trolox, einem hydrophilen Vitamin E-Analogon, gefunden wurde, wurde vermutet, dass α-Tocopherol die Degranulation möglicherweise durch seine membranständige Lokalisation beeinflussen könnte. Die Inkubation der Zellen mit α-Tocopherol resultierte in einer veränderten Verteilung des Gangliosids GM1, einem Lipid raft Marker. Es wird angenommen, dass diese Membranmikrodomänen als Plattformen für Signaltransduktionsvorgänge fungieren. Ein möglicher Einfluss von Vitamin E auf die Rekrutierung/Translokation von Signalproteinen in Membranmikrodomänen könnte die beobachteten Effekte erklären. Eine Rolle von α-Tocopherol im vesikulären Transport könnte nicht nur seine eigene Absorption und seinen Transport beeinflussen, sondern auch eine Erklärung für die bei schwerer Vitamin E-Defizienz auftretenden neuronalen Dysfunktionen bieten. Im zweiten Teil der Arbeit wurde die α-Tocopheroltransferprotein (Ttpa) Knockout-Maus als genetisches Modell für Vitamin E-Defizienz verwendet, um den Effekt von Ttpa auf die Genexpression und die Gewebeverteilung von α-Tocopherol zu analysieren. Ttpa ist ein cytosolisches Protein, das für die selektive Retention von α-Tocopherol in der Leber verantwortlich ist. Die Ttpa-Defizienz resultierte in sehr geringen α-Tocopherol-Konzentrationen im Plasma und den extrahepatischen Geweben. Die Analyse der α-Tocopherol-Gehalte im Gehirn wies auf eine Rolle von Ttpa bei der α-Tocopherol-Aufnahme ins Gehirn hin. N2 - Vitamin E is still considered the most important lipid-soluble antioxidant within biological membranes. However, in the last years the non-antioxidant functions of vitamin E have become the focus of vitamin E research. From the eight members of the vitamin E family, specific emphasis is given to α-tocopherol, the most abundant vitamin E form in mammalian tissues, and its role in the regulation of gene expression. The aim of this thesis was the analysis of the gene regulatory functions of α-tocopherol and the identification of α-tocopherol sensitive genes in vivo. For this purpose mice were fed diets differing in α-tocopherol content. The analysis of hepatic gene expression using DNA microarrays identified 387 α-tocopherol-sensitive genes. Functional cluster analyses of these differentially expressed genes demonstrated an influence of α-tocopherol on cellular transport processes. Especially the expression of genes involved in vesicular trafficking was largely upregulated by α-tocopherol. Upregulation of syntaxin 1C, vesicle-associated membrane protein 1, N-ethylmaleimide-sensitive factor and syntaxin binding protein 1 was verified by real time PCR. A role of α-tocopherol in exocytosis was shown by the in vitro β-hexosaminidase release assay in the secretory mast cell line RBL-2H3. Incubation with α-tocopherol resulted in a concentration dependent increase of PMA/ionomycin-stimulated secretion of β-hexosaminidase. Induction of selected genes involved in degranulation was not observed at any time point. Thus, a direct gene-regulatory effect of α-tocopherol seemed rather unlikely. Since increased secretion was also observed with ß-tocopherol but not with trolox, a water-soluble analog of vitamin E, it was hypothesized that α-tocopherol might affect degranulation through its localization at the plasma membrane. Incubation of cells with α-tocopherol changed the distribution of the gangliosid GM1, a Lipid raft marker. These membrane microdomains are assumed to function as signaling platforms. An possible influence of vitamin E on the recruitment/translocation of signaling proteins into membrane microdomains could explain the observed effects. A role of α-tocopherol in the vesicular transport might not only affect its own absorption and transport but also explain the neural dysfunctions observed in severe α-tocopherol deficiency. In the second part of this dissertation the α-tocopherol transfer protein (Ttpa) knockout-mouse as a model of genetic vitamin E deficiency was used to analyze the effect of Ttpa gene expression and tissue distribution of α-tocopherol. Ttpa is a cytosolic protein, which is responsible for the selective retention of α-tocopherol in the liver. Its deficiency resulted in very low α-tocopherol concentrations in plasma and extrahepatic tissues. Analysis of α-tocopherol contents in brain indicated a role for Ttpa in the uptake of α-tocopherol into the brain. KW - Vitamin E KW - Microarray KW - Genregulation KW - vesikulärer Transport KW - α-Tocopheroltransferprotein (Ttpa) KW - vitamin E KW - microarray KW - gene regulation KW - vesicular transport KW - alpha-tocopherol transfer protein (Ttpa) Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-35710 ER - TY - THES A1 - Walter, Thomas T1 - Volcano-tectonics: Volcano deformation, dynamics and structure affected by intrusions and earthquakes Y1 - 2009 CY - Potsdam ER - TY - BOOK A1 - Wenhold, Franziska A1 - Elbe, Anne-Marie A1 - Beckmann, Jürgen T1 - Volitionale Komponenten im Sport : Fragebogen zur Erfassung volutionaler Komponenten im Sport (VKS) Y1 - 2009 SN - 978-3-86884-509-9 PB - Sportverlag Strauß CY - Köln ER - TY - JOUR A1 - Partenheimer, Lutz T1 - Vom Hevellerfürstentum zur Mark Brandenburg Y1 - 2009 SN - 978-3-910011-56-4 ER - TY - THES A1 - Fischer, Andreas T1 - Vom Konflikt zur Begegnung? : Studien zu Islambildern im pädagogischen Jahrhundert Deutschlands Y1 - 2009 SN - 978-3-8288-9908-7 PB - Tectum-Verl. CY - Marburg ER - TY - JOUR A1 - Giest, Hartmut T1 - Vom Spiel zur Lerntätigkeit Y1 - 2009 SN - 978-3-7815-1675-5 ER - TY - JOUR A1 - Bahro, Berno T1 - Vom Umgang mit der eigenen nationalsozialistischen Geschichte : das Beispiel eines Berliner Turnvereins Y1 - 2009 SN - 978-3-643-10338-3 ER - TY - GEN A1 - Fink, Hans-Peter T1 - Von Biopolymeren und Biokunststoffen : Antrittsvorlesung 2009-06-04 N2 - Prof. Fink wird zum einen auf die industriell schon lange genutzten natürlichen Polymere wie Cellulose, Stärke und Lignin eingehen, zum anderen auf neue Entwicklungen bei biobasierten Kunststoffen. Von besonderer Bedeutung ist dabei die Aufklärung von Zusammenhängen zwischen Prozessparametern, Strukturen und Eigenschaften. Y1 - 2009 UR - http://info.ub.uni-potsdam.de/multimedia/show_projekt.php?projekt_id=35 PB - Univ.-Bibl. CY - Potsdam ER - TY - THES A1 - Herzberg, Carsten T1 - Von der Bürger- zur Solidarkommune : lokale Demokratie in Zeiten der Globalisierung Y1 - 2009 SN - 978-3-89965-372-4 PB - VSA-Verl. CY - Hamburg ER - TY - JOUR A1 - Flitner, Elisabeth A1 - van Zanten, Agnès T1 - Von der Konfessionsschule zum geschützten Sozialmilieu : Entwicklung und Funktionen des privaten Sektors im französichen Schulsystem Y1 - 2009 SN - 0044-3247 ER - TY - JOUR A1 - Raters, Marie-Luise T1 - Von Hegel zu Darwin : die Wurzeln von Deweys Ästhetik in der Ästhetik des angelsächsischen Idealismus N2 - This article traces the influences which American pragmatist philosophy and Dewey's pragmatist aesthetics in particular received from the various idealist traditions of (a) the English romantic philosopher-poets, (b) Cambridge Hegelians in the vein of Josiah Royce, (c-f) three different generations of Oxford Hegelians, from Bosanquet to Collingwood, and, most directly relevant for Dewey's philosophical development, (g) the late 19th century St. Louis Hegelians William Torrey Harris and George Silvester Morris. Another important influence for Dewey's pragmatism, as well as already for Bosanquet, was Darwinian evolutionary thought with its emphasis on the needs for adaptation. Central points of interest in the development of Dewey's aesthetics which he shared to some degree with the British and American idealists were the concept of aesthetic experience, the cognitive relevance of imaginative experiences and the practical relevance of fine art for developing shared forms of life. Y1 - 2009 SN - 0340-7969 ER - TY - BOOK A1 - Ehrlich, Ernst Ludwig ED - Homolka, Walter ED - Barniske, Tobias T1 - Von Hiob zu Horkheimer : gesammelte Schriften zum Judentum und seiner Umwelt T3 - Studia Judaica / Forschungen zur Wissenschaft des Judentums N2 - Ernst Ludwig Ehrlich (1921-2007), der bekannte Judaist und Historiker, begann seine akademische Laufbahn 1940 an der Berliner Hochschule fuer die Wissenschaft des Judentums. Im Jahr 1943 gelang ihm die Flucht aus dem nationalsozialistischen Deutschland in die Schweiz. Als Wissenschaftler wirkte er an den Universitaeten von Zuerich, Basel, Bern, Frankfurt a.M. und Berlin. Schon frueh setzte sich Ehrlich fuer einen Dialog zwischen Juden und Christen ein. Waehrend des Zweiten Vatikanischen Konzils war Ernst Ludwig Ehrlich als Berater des Kardinal Augustin Bea an der Ausarbeitung der Erklaerung Nostrae Aetate ueber die Beziehungen der Katholischen Kirche zu den nichtchristlichen Religionen beteiligt. Dieser Band vereint Texte von Ernst Ludwig Ehrlich zur Geschichte, Theologie und Ethik des Judentums und ehrt damit den Begruender der Reihe Studia Judaica. Sie verdeutlichen die Bandbreite seines wissenschaftlichen Interesses und sein lebenslanges Streben, Wissen ueber juedische Religion und Kultur einem breiten Publikum zu vermitteln. Y1 - 2009 UR - http://www.degruyter.de/cont/fb/th/detail.cfm?isbn=9783110219494&sel=det SN - 978-3-11-020257-1 VL - 47 PB - Walter de Gruyter GmbH Co.KG CY - Berlin ER - TY - JOUR A1 - Ette, Ottmar T1 - Von Paris über Beirut nach Havanna : transareale Reisebewegungen im literarischen Schaffen Amin Maaloufs Y1 - 2009 SN - 978-3-89528-731-2 ER - TY - JOUR A1 - Göse, Frank T1 - Von verschmähter Vasallität zu dynastischer Übereinkunft : die brandenburgisch-pommerschen Beziehungen zwischen dem ausgehenden 15. und dem frühen 17. Jahrhundert Y1 - 2009 ER - TY - JOUR A1 - Lauterbach, Roland A1 - Giest, Hartmut T1 - Vorwort Y1 - 2009 SN - 978-3-7815-1675-5 ER - TY - JOUR A1 - Ette, Ottmar T1 - Vorwort : Das Opus Americanum oder Das Mobile der Humboldtschen Wissenschaft Y1 - 2009 SN - 978-3-9811483-5-0 ER - TY - JOUR A1 - Prengel, Annedore T1 - Vorwort : Hoffnung und Herausforderung der "Pädagogik der Vielfalt" Y1 - 2009 SN - 978-3-7799-2137-0 ER - TY - JOUR A1 - Ette, Ottmar T1 - Vorwort: Die Insel als Welt : Alexander von Humboldt auf Teneriffa Y1 - 2009 SN - 3-87776-276-X ER - TY - BOOK A1 - Groß, Michael A1 - Wohlrath, Christin T1 - Wagniskapital für den kleinen und innovativen Mittelstand Y1 - 2009 SN - 978-3-89936-799-7 ER - TY - THES A1 - Grosenick, Christian T1 - Wahl und Gestaltung institutioneller Arrangements in der kommunalen Abfallwirtschaft Y1 - 2009 SN - 978-3-86573-453-2 PB - wvb Wiss. Verl. CY - Berlin ER - TY - THES A1 - Penzlin, Carsten T1 - Wahlkampf und Außenpolitik : eine vergleichende Studie zu den Bundestagswahlen von 1957 und 1972 Y1 - 2009 SN - 978-3-942129-18-3 PB - Baltic Sea Press CY - Rostock ER - TY - JOUR A1 - Heimann, Heinz-Dieter T1 - Was bleibt? : zur Rückkehr der "alten Stadt" in das kulturelle Gedächtnis Y1 - 2009 ER - TY - BOOK A1 - Abdolvand, Behrooz A1 - Liesener, Michael T1 - Was treibt den Ölpreis? BT - Oder: Der Versuch, die Pyramide auf die Beine zu stellen N2 - Der Rohölpreis wird über Angebot und Nachfrage reguliert – so jedenfalls die landläufige Auffassung. Die Autoren, beide ausgewiesene Energieexperten, zeigen jedoch auf, dass sich die drastischen Preisschwankungen auf den Energiemärkten nicht allein durch Marktmechanismen erklären lassen. Stattdessen führen sie den volatilen Ölpreis auf politische (Fehl-) Entscheidungen zurück und empfehlen einen Energiedialog zwischen Verbrauchern und Produzenten. T3 - Horizonte 21 : Umwelt · Energie · Sicherheit - 1 Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-29725 SN - 978-3-940793-86-7 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - BOOK ED - Budke, Alexandra ED - Bürkner, Hans-Joachim T1 - Wasser, Gesellschaft und städtischer Raum in Mexiko = Agua, sociedad y espacio urbano en México N2 - Ähnlich wie andere Metropolen in Entwicklungs- und Schwellenländern hat auch die zweitgrößte Stadt Mexikos, Guadalajara, enorme Schwierigkeiten seine Bevölkerung mit sauberem Trinkwasser zu versorgen und das Abwasser sozial- und umweltverträglich zu entsorgen. Gründe für die wachsenden Probleme hängen einerseits mit der Dynamik fortschreitender Urbanisierungsprozesse und andererseits mit der Zunahme sozialer und sozialräumlicher Disparitäten zusammen. Es werden empirische Arbeiten vorgestellt, die im Rahmen einer studentischen Exkursion entstanden sind und die sich mit dem Zusammenhang zwischen sozialräumlichen Disparitäten und der Wasserversorgung bzw. Abwasserentsorgung am innerstädtischen Flusslauf "Atemajac" beschäftigen. Dabei werden vor allem die unterschiedlichen Problemwahrnehmungen der Anwohner des Flusses und die von ihnen gesehenen Lösungsmöglichkeiten untersucht. T3 - Praxis Kultur- und Sozialgeographie | PKS - 45 KW - Stadtentwicklung KW - Mexiko KW - Wasserversorgung KW - Guadalajara KW - Megacity KW - sozialräumliche Disparitäten Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-28978 SN - 978-3-940793-78-2 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - BOOK A1 - Bar, Julia T1 - Wasserkonflikte in Zentralasien : Akteure, Interessendisparitäten und Ansätze für die Entschärfung des regionalen Konfliktpotentials N2 - In vielen Ländern ist Wassermangel ein zentrales Problem. Die Politikwissenschaftlerin Julia Bar ist der Ansicht, dass diese Krise in politischem und gesellschaftlichem Unvermögen der beteiligten Akteure begründet ist. Am Beispiel Zentralasiens analysiert die Autorin das Konfliktpotenzial der Ressource Wasser anhand der zwischen- und innerstaatlichen Dimension. Es werden die Nutzungs- und Verteilungskonflikte um das Wasser in der Region sowie die Faktoren zur Verbesserung der nachhaltigen Wassernutzung untersucht. Als zentraler Lösungsansatz wird das Konzept des Integrierten Wasserressourcen-Managements behandelt und seine Anwendbarkeit in Bezug auf Zentralasien diskutiert. Die Autorin kommt zu dem Schluss, dass für die Etablierung eines nachhaltigen Ressourcennutzungssystems Kooperation und Konsensfindung der Akteure entscheidend sind. T3 - WeltTrends Thesis - 5 KW - Zentralasien KW - Wasser KW - Konfliktmanagement KW - Internationale Politik KW - Central Asia KW - Water KW - Conflict Management KW - International Relations Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-27688 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Stockhorst, Stefanie T1 - Wehringer, B. (Hrsg.), Brown, H. (Hrsg.), Übersetzungskultur im 18. Jahrhundert Übersetzerinnen in Deutschland, Frankreich und der Schweiz; Hannover, Werhahn, 2008 BT - Übersetzungskultur im 18. Jahrhundert Übersetzerinnen in Deutschland, Frankreich und der Schweiz Y1 - 2009 SN - 978-3-8353-0503-8 ER - TY - JOUR A1 - Grosse, Sybille T1 - Welker, H. A., Dicionários: uma pequena interodução à lexicografia; Brasília, Thesaurus, 2004 BT - Dicionários : uma pequena interodução à lexicografia Y1 - 2009 SN - 0931-9484 ER - TY - BOOK A1 - Stahl, Sebastian A1 - Fuhrmann, Wilfried T1 - Wertschöpfung in der zeitgenössischen Kunst : Zur "Young German Art" T3 - Forschungsbericht Y1 - 2009 SN - 978-3-9812422-2-5 VL - 0109 PB - Inst. für Makroökonomik Univ. Potsdam CY - Potsdam ER - TY - BOOK A1 - Creuzberger, Stefan T1 - Westintegration und Neue Ostpolitik : die Außenpolitik der Bonner Republik T3 - Deutsche Geschichte im 20. Jahrhundert Y1 - 2009 SN - 978-3-89809-414-6 VL - 14 PB - be.bra-Verl. CY - Berlin ER - TY - THES A1 - Schmidt, Bendikt T1 - Wettbewerbsvorteile im SAP-Outsourcing durch Wissensmanagment : Methoden zur effizienten Gestaltung des Übergangs ins Application Managment Y1 - 2009 SN - 978-3-940019-93-6 PB - Gito-Verl. CY - Berlin ER - TY - JOUR A1 - Olk, Thomas A1 - Speck, Karsten T1 - What can be achieved by social work at schools? : Theoretical concepts and empirical findings at the section between formal and non-formal education N2 - In the educational-political reform plans of the last few years (e.g. the federal all-day schooling program), different forms of cooperation between institutions of help for young people and schools have increasingly gained in significance. However, empirically solid knowledge on the effects of this cooperation is still rather limited. Taking as an example social work at schools, which is considered the closest form of cooperation between institutions of help for young people and schools, the authors analyze the state of knowledge on the effects, the interrelations of these effects, and the limits of the cooperation between institutions of help for adolescents and schools in the shape of action programs for school-related social work. By means of a meta-analysis of available empirical studies, the insights that have been generated so far as well as the deficits and blind spots of existing research and the subject-related and methodological challenges in future research on the effects and the use of social work are discussed. Y1 - 2009 SN - 0044-3247 ER - TY - JOUR A1 - Kosman, Admiʾel T1 - What did Cain say to Abel? Y1 - 2009 SN - 1614-6492 ER - TY - JOUR A1 - Dreyer, Ingo A1 - Blatt, Michael R. T1 - What makes a gate? : the ins and outs of Kv-like K+ channels in plants N2 - Gating of K+ and other ion channels is 'hard-wired' within the channel protein. So it remains a puzzle how closely related channels in plants can show an unusually diverse range of biophysical properties. Gating of these channels lies at the heart of K+ mineral nutrition, signalling, abiotic and biotic stress responses in plants. Thus, our knowledge of the molecular mechanics underpinning K+ channel gating will be important for rational engineering of related traits in agricultural crops. Several key studies have added significantly to our understanding of channel gating in plants and have challenged current thinking about analogous processes found in animal K+ channels. Such studies highlight how much of K+ channel gating remains to be explored in plants. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/13601385 U6 - https://doi.org/10.1016/j.tplants.2009.04.001 SN - 1360-1385 ER - TY - THES A1 - Itonaga, Naomi T1 - White storks (Ciconia ciconia) of Eastern Germany: age-dependent breeding ability, and age- and density-dependent effects on dispersal behavior T1 - Der Weißstorch (Ciconia ciconia) aus dem östlichen Deutschland: altersabhängiges Reproduktionsvermögen und alters- und bestandsdichteabhängiges Ausbreitungsverhalten N2 - Dispersal behavior plays an important role for the geographical distribution and population structure of any given species. Individual’s fitness, reproductive and competitive ability, and dispersal behavior can be determined by the age of the individual. Age-dependent as well as density-dependent dispersal patterns are common in many bird species. In this thesis, I first present age-dependent breeding ability and natal site fidelity in white storks (Ciconia ciconia); migratory birds breeding in large parts of Europe. I predicted that both the proportion of breeding birds and natal site fidelity increase with the age. After the seventies of the last century, following a steep population decline, a recovery of the white stork population has been observed in many regions in Europe. Increasing population density in the white stork population in Eastern Germany especially after 1983 allowed examining density- as well as age-dependent breeding dispersal patterns. Therefore second, I present whether: young birds show more often and longer breeding dispersal than old birds, and frequency of dispersal events increase with the population density increase, especially in the young storks. Third, I present age- and density-dependent dispersal direction preferences in the give population. I asked whether and how the major spring migration direction interacts with dispersal directions of white storks: in different age, and under different population densities. The proportion of breeding individuals increased in the first 22 years of life and then decreased suggesting, the senescent decay in aging storks. Young storks were more faithful to their natal sites than old storks probably due to their innate migratory direction and distance. Young storks dispersed more frequently than old storks in general, but not for longer distance. Proportion of dispersing individuals increased significantly with increasing population densities indicating, density- dependent dispersal behavior in white storks. Moreover, the finding of a significant interaction effects between the age of dispersing birds and year (1980–2006) suggesting, older birds dispersed more from their previous nest sites over time due to increased competition. Both young and old storks dispersed along their spring migration direction; however, directional preferences were different in young storks and old storks. Young storks tended to settle down before reaching their previous nest sites (leading to the south-eastward dispersal) while old birds tended to keep migrating along the migration direction after reaching their previous nest sites (leading to the north-westward dispersal). Cues triggering dispersal events may be age-dependent. Changes in the dispersal direction over time were observed. Dispersal direction became obscured during the second half of the observation period (1993–2006). Increase in competition may affect dispersal behavior in storks. I discuss the potential role of: age for the observed age-dependent dispersal behavior, and competition for the density dependent dispersal behavior. This Ph.D. thesis contributes significantly to the understanding of population structure and geographical distribution of white storks. Moreover, presented age- and density (competition)-dependent dispersal behavior helps understanding underpinning mechanisms of dispersal behavior in bird species. N2 - Das Verständnis der Mechanismen, die dem Ausbreitungsverhalten und der Wahl des Neststandorts zugrunde liegen, gibt wichtige Einsichten in Strukturen und Dynamiken von Tierpopulationen. Der Gesundheitszustand, die Produktivität und Konkurrenzfähigkeit sowie das Ausbreitungsverhalten eines Individuums können über das Alter ermittelt werden. Alters- und dichteabhängige Veränderungen in Verbreitungsmustern kommen bei vielen Vogelarten vor. In der vorliegenden Studie untersuchten wir zunächst den Effekt des Alters auf die Reproduktivität, auf die Wahl des Neststandorts sowie auf die Geburtsorttreue des Weißstorchs (Ciconia ciconia). Wir fragten, ob sowohl der Anteil der brütenden Individuen als auch die Geburtsorttreue mit dem Alter zunimmt. Weißstörche sind Zugvögel, die während der Migration zumeist segelnd die Thermik nutzen und in weiten Teilen Europas brüten. Nach einem starken Bestandsrückgang konnte in vielen Regionen Europas ab den 1970er Jahren wieder ein positiver Trend in der Populationsentwicklung beobachtet werden. Die zunehmende Populationsdichte, besonders nach 1983 in der ostziehenden Subpopulation in den fünf Bundesländern der ehemaligen DDR, erlaubte die Analyse von dichte- und altersabhängigen Präferenzen in der Richtung der Brutstandorte sowie in der Verbreitungsfrequenz und -distanz. Wir untersuchten zudem die Alters- und Dichteabhängigkeit der Ausbreitungsrichtung einer Teilpopulation. Wir fragten, ob und wie die Hauptzugrichtung im Frühjahr mit der Verbreitungsrichtung interagiert: Beeinflussen Alter und Populationsdichte die Ausbreitungsrichtung? Der Anteil der brütenden Individuen, die älter als 22 Jahre sind, nahm innerhalb der beobachteten Teilpopulation ab, vermutlich aufgrund einer altersbedingten Abnahme des Gesundheitszustands. Junge Vögel zeigten eine starke Geburtsorttreue, was auf eine genetische Komponente in den Zugmustern junger Störche hinweist. Generell trat bei jungen Störchen häufiger Ausbreitungsverhalten auf als bei älteren Störchen. Eine signifikante Zunahme der Ausbreitungsdistanz von Individuen über die Zeit lässt auf eine dichteabhängige Komponente im Ausbreitungsverhalten der Weißstörche schließen. Weiterhin wurde eine signifikante Interaktion zwischen dem Alter sich ausbreitender Individuen und dem betrachteten Jahr gefunden. Demzufolge breiteten sich alte Vögel über die Zeit über größere Distanzen aus, vermutlich um der ansteigenden Konkurrenz, bedingt durch den wachsenden Bestandsdruck, zu entgehen. KW - Weißstorch KW - Altersabhängigkeit KW - Dichteabhängigkeit KW - Ausbreitungsverhalten KW - Reproduktivität KW - White stork KW - age-dependent KW - density-dependent KW - dispersal behavior KW - breeding ability Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-39052 ER - TY - JOUR A1 - Stöcker, Ralf T1 - Why animals can't act N2 - Given the many marvelous things animals can do and moreover the success we have in employing the intentional stance towards animals, it seems to be almost unthinkable to say that animals could not act at all. Nonetheless, this is exactly what I argue for. I claim that strictly speaking there is no animal action, only behaviour. I defend this claim in three steps. Firstly, I recapitulate some of the weighty grounds that speak in favour of animal agency. Secondly, I explain why I still doubt that animals act. The argument is that the account of agency that I take to be the most attractive one entails that animals can't act. Since this account of agency is non-standard, I spend the bulk of the paper with providing a sketch of what, according to it, actions are. Finally, I explain why it is still so natural and promising to regard animals as agents, although in fact they aren't. As one might put it: of course they act, only strictly speaking they don't. Y1 - 2009 UR - http://www.informaworld.com/openurl?genre=journal&issn=0020-174X U6 - https://doi.org/10.1080/00201740902917135 SN - 0020-174X ER - TY - JOUR A1 - Miller, Jeff A1 - Ulrich, Rolf A1 - Schwarz, Wolfgang T1 - Why jackknifing yields good latency estimates N2 - We compared individual-participant and jackknife-based methods for scoring the onset latencies of event-related potential (ERP) components using a diffusion process as a model for an ERP. We studied "ramp-like" components in which the true ERP increases or decreases monotonically, except for noise. If the growth rates of such components vary across participants, the jackknife-based measure can easily have only 10%-20% as much error variance as the traditional method, and this advantage is magnified with more participants. We also studied boolean AND-shaped or "bump-like" components. Jackknifing generally yielded smaller error variances with these components too, especially when the component's peak amplitude varied across participants, but less so if the component's peak latency varied. These results help illuminate the reasons for the superiority of jackknife-based onset latency measures over traditional measures in recent simulations. Y1 - 2009 UR - http://www3.interscience.wiley.com/cgi-bin/issn?DESCRIPTOR=PRINTISSN&VALUE=0048-5772 U6 - https://doi.org/10.1111/j.1469-8986.2008.00761.x SN - 0048-5772 ER - TY - BOOK A1 - Hübner, Sandra T1 - Wie Online-Werkszeuge eine maßgeschneiderte Veranstaltungkonzeption unterstützen können Y1 - 2009 UR - http://info.ub.uni-potsdam.de/multimedia/show_projekt.php?projekt_id=56 PB - Univ.-Bibl. CY - Potsdam ER - TY - GEN A1 - Tristram, Hildegard L.C. T1 - Wie weit sind die inselkeltischen Sprachen (und das Englische) analytisiert? T1 - How far have the Insular Celtic languages (and the English language) been analyticised? N2 - Der gemeinsame Wandel der inselkeltischen Sprachen wie auch des Englischen vom vorwiegend synthetischen Typus zum vorwiegend analytischen Typus läßt sich vermutlich auf einen ca. 1500 Jahre dauernden intensiven Sprachenkontakt zwischen diesen Sprachen zurückführen. Heute ist das Englische die analytischste Sprache der Britischen Inseln und Irlands, gefolgt vom Walisischen, Bretonischen und Irischen. Letzteres ist von den genannten Sprachen noch am weitesten morphologisch komplex. N2 - I discuss the joint shift of the Insular Celtic languages and of the English language from, typologically speaking, predominantly synthetic languages c. 1500 years ago to predominantly analytical languages today. The demise of the inflectional morphology is most advanced in Present Day English. Welsh follows suit. Then come Breton and Irish. Intensive linguistic interaction across the boundaries of the Germanic and the Insular Celtic languages are proposed to have been instrumental for this type of linguistic convergence. T3 - Zweitveröffentlichungen der Universität Potsdam : Philosophische Reihe - 35 KW - Irisch KW - Walisisch KW - Bretonisch KW - Englisch KW - Sprachwandel KW - Sprachkontakt KW - Sprachkonvergenz KW - Typologie KW - Morphologie KW - Komplexität KW - Quantifizierun KW - Irish KW - Welsh KW - Breton KW - English KW - Language Change KW - Language Contact KW - Convergence KW - Morphology KW - Complexity KW - Quantification Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-41251 ER - TY - JOUR A1 - Valdivia Orozco, Pablo Emilio T1 - Wiederholte Wiederholung JF - Happy Days : Lebenswissen nach Cavell Y1 - 2009 SN - 978-3-7705-4725-8 SP - 292 EP - 297 PB - Fink CY - Paderborn ER - TY - JOUR A1 - Wiemann, Dirk T1 - Wilber's Force : abolitionism and the power of sensibility in Michael Apted's amazing grace Y1 - 2009 SN - 0171-1695 ER - TY - GEN A1 - Bircken, Margrid T1 - Wilhelm Fraenger (1890 bis 1964) und Anna Seghers (1900 bis 1983) T3 - Zweitveröffentlichungen der Universität Potsdam : Philosophische Reihe - 71 Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-44546 ER - TY - JOUR A1 - Esser, Günter A1 - Bakhshayesh, Ali Reza A1 - Drüge, Sebastian A1 - Ihle, Wolfgang T1 - Wirksamkeit von Neuro- und EMG-Feedback bei Kindern mit ADHS : eine Follow-up-Studie Y1 - 2009 ER - TY - BOOK A1 - Gronau, Norbert T1 - Wissen prozessorientiert managen : Methode und Werkzeuge für die Nutzung des Wettbewerbsfaktors Wissen in Unternehmen Y1 - 2009 SN - 978-3-486-59020-3 PB - Oldenbourg CY - München ER - TY - JOUR A1 - Petsche, Hans-Joachim T1 - Wissenschaft und Emotionalität Y1 - 2009 SN - 978-3-643-50081-6 ER - TY - JOUR A1 - Hanke, Christine T1 - Wissenschaftliche Konstruktionen von "Rasse" und "Geschlecht" in der Anthropologie um 1900 Y1 - 2009 SN - 978-3-89771-475-5 ER -