TY - CHAP A1 - Knoth, Alexander Henning A1 - Kiy, Alexander T1 - (Self-)confident through the introductory study phase with the Reflect App BT - (Self-)confident through the introductory study phase with the Reflect App T2 - CEUR Workshop Proceedings T2 - Selbst-bewusst durch die Studieneingangsphase mit der Reflect-App Y1 - 2014 UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84921875162&partnerID=MN8TOARS SN - 1613-0073 IS - 1227 SP - 172 EP - 179 PB - CEUR-WS CY - Freiburg ER - TY - CHAP T1 - 11. Workshop Testmethoden und Zuverlässigkeit von Schaltungen und Systemen BT - vom 28. Februar bis 2. März, Potsdam-Hermannswerder, Inselhotel Y1 - 1999 SN - 978-3-9806494-1-4 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - CHAP A1 - Engbert, Ralf T1 - A computational model of microsaccadic responses to shifts of covert attention T2 - Perception Y1 - 2012 SN - 0301-0066 SN - 1468-4233 VL - 41 SP - 55 EP - 55 PB - Sage Publ. CY - London ER - TY - CHAP A1 - Fischer, Martin H. T1 - A hierarchical view of grounded, embodied, and situated numerical cognition T2 - Cognitive processing : international quarterly of cognitive science Y1 - 2012 SN - 1612-4782 VL - 13 SP - S14 EP - S15 PB - Springer CY - Heidelberg ER - TY - CHAP A1 - Tikhonenko, I. A1 - Magidson, V. A1 - Gräf, Ralph A1 - Khodjakov, A. A1 - Koonce, M. T1 - A kinesin-mediated linkage between centrosomes and the nuclear envelope T2 - Molecular biology of the cell : the official publication of the American Society for Cell Biology Y1 - 2011 SN - 1059-1524 VL - 22 IS - 1 PB - American Society for Cell Biology CY - Bethesda ER - TY - CHAP A1 - Haralampiev, Ivan A1 - Mertens, Monique A1 - Schwarzer, Roland A1 - Herrmann, Andreas A1 - Volkmer, Rudolf A1 - Wessig, Pablo A1 - Müller, Peter T1 - A palmitic acid functionalized with a maleimide group is used to recruit SH-containing peptides to lipid and biological membranes T2 - The FEBS journal Y1 - 2015 SN - 1742-464X SN - 1742-4658 VL - 282 SP - 204 EP - 204 PB - Wiley-Blackwell CY - Hoboken ER - TY - CHAP A1 - Giraudier, Manon A1 - Ventura-Bort, Carlos A1 - Weymar, Mathias T1 - A pooled preliminary analysis on the effects of transcutaneous auricular vagus nerve stimulation on salivary alpha-amylase as noradrenergic biomarker T2 - Psychophysiology : journal of the Society for Psychophysiological Research KW - Transcutaneous Auricular Vagus Nerve Stimulation KW - Salivary KW - Alpha-amylase KW - Pooled Data Y1 - 2021 SN - 1469-8986 VL - 58 SP - S60 EP - S60 PB - Wiley-Blackwell CY - Malden, Mass. [u.a.] ER - TY - CHAP A1 - Grüner, Andreas A1 - Mühle, Alexander A1 - Gayvoronskaya, Tatiana A1 - Meinel, Christoph T1 - A quantifiable trustmModel for Blockchain-based identity management T2 - IEEE 2018 International Congress on Cybermatics / 2018 IEEE Conferences on Internet of Things, Green Computing and Communications, cyber, physical and Social Computing, Smart Data, Blockchain, Computer and Information Technology KW - Blockchain KW - distributed ledger technology KW - digital identity KW - self-sovereign identity KW - trust KW - identity management Y1 - 2019 SN - 978-1-5386-7975-3 U6 - https://doi.org/10.1109/Cybermatics_2018.2018.00250 SP - 1475 EP - 1482 PB - IEEE CY - New York ER - TY - CHAP A1 - Baranyai, Dorothea A1 - Goedtel-Armbrust, Ute A1 - Nestler, Sebastian A1 - Kleuser, Burkhard A1 - Wojnowski, Leszek T1 - A role for cutaneous CYP3A in vitamin D homeostasis? T2 - NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY Y1 - 2014 SN - 0028-1298 SN - 1432-1912 VL - 387 SP - S27 EP - S27 PB - Springer CY - New York ER - TY - CHAP A1 - Freudenberg, Maxi A1 - Mauersberger, Heidi A1 - Springer, Anne A1 - Fotopoulou, Aikaterini A1 - Blaison, Christophe A1 - Hess, Ursula T1 - A woman's best friend how the presence of dogs reduces Experimentally induced pain T2 - Psychophysiology : journal of the Society for Psychophysiological Research KW - EMG KW - cold pressor pain Y1 - 2013 SN - 0048-5772 VL - 50 SP - S103 EP - S103 PB - Wiley-Blackwell CY - Hoboken ER - TY - CHAP A1 - Le, Dinh To A1 - Behrsing, Olaf A1 - Rothschild, Claire A1 - Radukic, Marco T. A1 - Arndt, Katja A1 - Müller, Kristian M. T1 - AAV capsid proteins fused with SARS-CoV-2 RBD or RBM: Expression in E. coli, in-vitro assembly, and characterization BT - 24th Annual Meeting of the American Society of Gene & Cell Therapy : Complete listing of the accepted abstracts for presentation at ASGCT's 24th Annual Meeting, May 11-May 14, 2021 T2 - Molecular therapy : the journal of the American Society of Gene Therapy Y1 - 2021 U6 - https://doi.org/10.1016/j.ymthe.2021.04.019 SN - 1525-0016 SN - 1525-0024 VL - 29 IS - 4, Suppl. 1 SP - 357 EP - 357 PB - Cell Press CY - Cambridge ER - TY - CHAP A1 - Grum, Marcus A1 - Rapp, Simon A1 - Gronau, Norbert A1 - Albers, Albert ED - Shishkov, Boris T1 - Accelerating knowledge BT - the speed optimization of knowledge transfers T2 - Business modeling and software design N2 - As knowledge-intensive processes are often carried out in teams and demand for knowledge transfers among various knowledge carriers, any optimization in regard to the acceleration of knowledge transfers obtains a great economic potential. Exemplified with product development projects, knowledge transfers focus on knowledge acquired in former situations and product generations. An adjustment in the manifestation of knowledge transfers in its concrete situation, here called intervention, therefore can directly be connected to the adequate speed optimization of knowledge-intensive process steps. This contribution presents the specification of seven concrete interventions following an intervention template. Further, it describes the design and results of a workshop with experts as a descriptive study. The workshop was used to assess the practical relevance of interventions designed as well as the identification of practical success factors and barriers of their implementation. KW - knowledge transfers KW - business process optimization KW - interventions KW - product development KW - product generation engineering KW - empirical evaluation Y1 - 2019 SN - 978-3-030-24853-6 SN - 978-3-030-24854-3 U6 - https://doi.org/10.1007/978-3-030-24854-3_7 VL - 356 SP - 95 EP - 113 PB - Springer CY - Cham ER - TY - CHAP A1 - Vladova, Gergana A1 - Jennifer, Haase A1 - Stricker, Dennis T1 - Acceptance in Human-Robot Interaction BT - user's personality and the anthropomorphic design of the robot as influencing factors N2 - This paper aims to contribute to exploring the design possibilities of robots for use in human-robot interaction. In an experiment, we investigate the influence of the human's personality and the robot's design, especially its humanization, on its acceptance. We use the Almere model, the Big 5 personality traits, and the anthropomorphic gestalt variants to build the foundation for our investigation. The assumption that an anthropomorphized robot variant would, in principle, be preferred to the standard variant when a natural choice is enforced could not be evidenced in our experiment. This allows for the interpretation that anthropomorphism does not necessarily lead to intentional perception and, consequently, does not guarantee that it can automatically generate acceptance. Y1 - 2022 CY - Sydney ER - TY - CHAP A1 - Cassel, Michael A1 - Carlsohn, Anja A1 - Froehlich, Katja A1 - Mayer, Frank T1 - Achilles tendinopathy in adolescent athletes using ultrasound and clinical examination T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2013 SN - 0195-9131 SN - 1530-0315 VL - 45 IS - 5 SP - 350 EP - 350 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Hain, Gerrit A1 - Cassel, Michael A1 - Intziegianni, Konstantina A1 - Mayer, Frank T1 - Achilles tendon cross-sectional area changes during maximal voluntary isometric plantar-flexion contraction in healthy individuals. T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2014 SN - 0195-9131 SN - 1530-0315 VL - 46 IS - 5 SP - 47 EP - 47 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Lindemann, Oliver A1 - Paulus, Markus T1 - Acquisition of action knowledge through verbal and social learning T2 - Cognitive processing : international quarterly of cognitive science Y1 - 2012 SN - 1612-4782 VL - 13 IS - 3 SP - S10 EP - S10 PB - Springer CY - Heidelberg ER - TY - CHAP A1 - Henze, Andrea A1 - Raila, Jens A1 - Scholze, Alexandra A1 - Schweigert, Florian J. A1 - Tepel, Martin T1 - Administration of N-Acetylcyteine causes beneficial posttranslationalmodifications of transthyretin in hemodialysis patients T2 - Nephrology, dialysis, transplantation Y1 - 2013 SN - 0931-0509 VL - 28 IS - 2 SP - 164 EP - 164 PB - Oxford Univ. Press CY - Oxford ER - TY - CHAP A1 - Völler, Heinz A1 - Salzwedel, Annett A1 - Reibis, Rona Katharina A1 - Kaminski, S. A1 - Buhlert, Hermann A1 - Eichler, Sarah A1 - Wegscheider, Karl T1 - Age and fitness level are strongest limitations of exercise capacity during inpatient cardiac rehabilitation T2 - European heart journal Y1 - 2014 SN - 0195-668X SN - 1522-9645 VL - 35 SP - 899 EP - 899 PB - Oxford Univ. Press CY - Oxford ER - TY - CHAP A1 - Grum, Marcus A1 - Thim, Christof A1 - Roling, Wiebke A1 - Schüffler, Arnulf A1 - Kluge, Annette A1 - Gronau, Norbert ED - Masrour, Tawfik ED - El Hassani, Ibtissam ED - Barka, Noureddine T1 - AI case-based reasoning for artificial neural networks T2 - Artificial intelligence and industrial applications N2 - Faced with the triad of time-cost-quality, the realization of production tasks under economic conditions is not trivial. Since the number of Artificial-Intelligence-(AI)-based applications in business processes is increasing more and more nowadays, the efficient design of AI cases for production processes as well as their target-oriented improvement is essential, so that production outcomes satisfy high quality criteria and economic requirements. Both challenge production management and data scientists, aiming to assign ideal manifestations of artificial neural networks (ANNs) to a certain task. Faced with new attempts of ANN-based production process improvements [8], this paper continues research about the optimal creation, provision and utilization of ANNs. Moreover, it presents a mechanism for AI case-based reasoning for ANNs. Experiments clarify continuously improving ANN knowledge bases by this mechanism empirically. Its proof-of-concept is demonstrated by the example of four production simulation scenarios, which cover the most relevant use cases and will be the basis for examining AI cases on a quantitative level. KW - case-based reasoning KW - neural networks KW - industry 4.0 Y1 - 2023 SN - 978-3-031-43523-2 SN - 978-3-031-43524-9 U6 - https://doi.org/10.1007/978-3-031-43524-9_2 VL - 771 SP - 17 EP - 35 PB - Springer CY - Cham ER - TY - CHAP A1 - Doyon, Anke A1 - Schmiedchen, Bettina A1 - Bayazit, Aysun A1 - Canpolat, Nur A1 - Duzova, Ali A1 - Kracht, Daniela A1 - Litwin, Mieczyslaw A1 - Niemirska, Anna A1 - Sozeri, Betul A1 - Zeller, Rene A1 - Anarat, Ali A1 - Caliskan, Salim A1 - Mir, Sevgi A1 - Shroff, Rukshana A1 - Melk, Anette A1 - Wühl, Elke A1 - Schweigert, Florian J. A1 - Querfeld, Uwe A1 - Schäfer, Franz T1 - Altered arterial morphology and function in children with CKD Role of mineral-bone disorder T2 - Pediatric nephrology : journal of the International Pediatric Nephrology Association Y1 - 2012 SN - 0931-041X VL - 27 IS - 9 SP - 1606 EP - 1607 PB - Springer CY - New York ER - TY - CHAP A1 - Abramova, Olga A1 - Gladkaya, Margarita A1 - Krasnova, Hanna T1 - An unusual encounter with oneself BT - exploring the impact of self-view on online meeting outcomes T2 - ICIS 2021: IS and the future of work N2 - Helping overcome distance, the use of videoconferencing tools has surged during the pandemic. To shed light on the consequences of videoconferencing at work, this study takes a granular look at the implications of the self-view feature for meeting outcomes. Building on self-awareness research and self-regulation theory, we argue that by heightening the state of self-awareness, self-view engagement depletes participants’ mental resources and thereby can undermine online meeting outcomes. Evaluation of our theoretical model on a sample of 179 employees reveals a nuanced picture. Self-view engagement while speaking and while listening is positively associated with self-awareness, which, in turn, is negatively associated with satisfaction with meeting process, perceived productivity, and meeting enjoyment. The criticality of the communication role is put forward: looking at self while listening to other attendees has a negative direct and indirect effect on meeting outcomes; however, looking at self while speaking produces equivocal effects. Y1 - 2021 UR - https://aisel.aisnet.org/icis2021/is_future_work/is_future_work/16 PB - AIS Electronic Library (AISeL) CY - [Erscheinungsort nicht ermittelbar] ER - TY - CHAP A1 - Machumi, F. A1 - Yenesew, Abiy A1 - Midiwo, J. O. A1 - Heydenreich, Matthias A1 - Kleinpeter, Erich A1 - Khan, S. A1 - Tekwani, B. L. A1 - Walker, L. A. A1 - Muhammad, I T1 - Antiparasitic and anticancer carvotacetone derivatives from Sphaeranthus bullatus T2 - Planta medica : journal of medicinal plant and natural product research Y1 - 2012 SN - 0032-0943 VL - 78 IS - 11 SP - 1201 EP - 1202 PB - Thieme CY - Stuttgart ER - TY - CHAP A1 - Laucht, Manfred A1 - Blomeyer, Dorothea A1 - El-Faddagh, Mahha A1 - Esser, Günter A1 - Schmidt, Martin A1 - Banaschewski, Tobias A1 - Becker, Katja T1 - Are regulatory problems in infancy precursors of ADHD in childhood? a moderating role for the dopamine D4 receptor gene T2 - Infant mental health journal Y1 - 2011 SN - 0163-9641 VL - 32 IS - 3 SP - 212 EP - 212 PB - Wiley-Blackwell CY - Hoboken ER - TY - CHAP A1 - Wannek, Dshamilja L. M. A1 - Reimold, Wolf Uwe A1 - Thirlwall, Matthew A1 - Hansen, Bent T. A1 - Schulz, Toni A1 - Hoffmann, Michael A1 - Zaag, Patrice T. A1 - Hauser, Natalia A1 - Siegert, Susann T1 - Are there two types of vredefort granophyre? T2 - Meteoritics & planetary science : journal of the Meteoritical Society Y1 - 2015 SN - 1086-9379 SN - 1945-5100 VL - 50 PB - Wiley-Blackwell CY - Hoboken ER - TY - CHAP A1 - Hanke-Gogokhia, Christin A1 - Frederick, Jeanne M. A1 - Zhang, Houbin A1 - Baehr, Wolfgang T1 - ARL3 regulates transport of prenylated and acylated proteins to photoreceptor outer segment in mouse retina T2 - Investigative ophthalmology & visual science Y1 - 2015 SN - 0146-0404 SN - 1552-5783 VL - 56 IS - 7 PB - Association for Research in Vision and Opthalmology CY - Rockville ER - TY - CHAP A1 - Rietsch, Katrin A1 - Scheffler, Christiane T1 - Association between skeletal robustness and physical activity in schoolchildren - First results T2 - Journal of biological and clinical anthropology : Anthropologischer Anzeiger ; Mitteilungsorgan der Gesellschaft für Anthropologie Y1 - 2011 SN - 0003-5548 VL - 68 IS - 4 SP - 516 EP - 516 PB - Schweizerbart CY - Stuttgart ER - TY - CHAP A1 - Vukicevic, Radovan A1 - Schreiber, Ulrike A1 - Beuermann, Sabine T1 - Azide-terminated poly(vinylidene fluoride) as building block for nanocomposite materials and block copolymers T2 - Abstracts of papers : joint conference / The Chemical Institute of Cananda, CIC, American Chemical Society, ACS Y1 - 2011 SN - 0065-7727 VL - 242 IS - 16 PB - American Chemical Society CY - Washington ER - TY - CHAP A1 - Stephan, Mareike Sophia A1 - Barbirz, Stefanie A1 - Robinson, Tom A1 - Yandrapalli, Naresh A1 - Dimova, Rumiana T1 - Bacterial mimetic systems for studying bacterial inactivation and infection BT - Meeting abstract: 65th Annual Meeting of the Biophysical Society (BPS), Feb. 22-26, 2021 T2 - Biophysical journal : BJ / ed. by the Biophysical Society Y1 - 2021 U6 - https://doi.org/10.1016/j.bpj.2020.11.1087 SN - 0006-3495 SN - 1542-0086 VL - 120 IS - 3 SP - 148A EP - 148A PB - Cell Press CY - Cambridge ER - TY - CHAP ED - Kortenkamp, Ulrich ED - Kuzle, Ana T1 - Beiträge zum Mathematikunterricht 2017 BT - Vorträge auf der 51. Tagung für Didaktik der Mathematik vom 27.02.2017 bis 02.03.2017 in Potsdam Y1 - 2018 UR - http://www.wtm-verlag.de/beitraege-zum-mathematikunterricht/ SN - 978-3-95987-072-6 SN - 978-3-95987-089-4 PB - WTM-Verlag CY - Münster ER - TY - CHAP A1 - Schlaad, Helmut A1 - Luedecke, Nils T1 - Bio-sourced chelating poly(2-oxazoline)s T2 - Abstracts of papers : joint conference / The Chemical Institute of Cananda, CIC, American Chemical Society, ACS Y1 - 2019 SN - 0065-7727 VL - 257 PB - American Chemical Society CY - Washington ER - TY - CHAP A1 - Heinz, A. A1 - Kluge, U. A1 - Schouler-Ocak, M. A1 - Rapp, Michael Armin T1 - Biological Effects of Social Exclusion T2 - European psychiatry : the journal of the Association of European Psychiatrists N2 - Timing and magnitude of surface uplift are key to understanding the impact of crustal deformation and topographic growth on atmospheric circulation, environmental conditions, and surface processes. Uplift of the East African Plateau is linked to mantle processes, but paleoaltimetry data are too scarce to constrain plateau evolution and subsequent vertical motions associated with rifting. Here, we assess the paleotopographic implications of a beaked whale fossil (Ziphiidae) from the Turkana region of Kenya found 740 km inland from the present-day coastline of the Indian Ocean at an elevation of 620 m. The specimen is similar to 17 My old and represents the oldest derived beaked whale known, consistent with molecular estimates of the emergence of modern straptoothed whales (Mesoplodon). The whale traveled from the Indian Ocean inland along an eastward-directed drainage system controlled by the Cretaceous Anza Graben and was stranded slightly above sea level. Surface uplift from near sea level coincides with paleoclimatic change from a humid environment to highly variable and much drier conditions, which altered biotic communities and drove evolution in east Africa, including that of primates. Y1 - 2015 SN - 0924-9338 SN - 1778-3585 VL - 30 PB - Elsevier CY - Paris ER - TY - CHAP A1 - Schreiber, Ulrike A1 - Vukicevic, Radovan A1 - Beuermann, Sabine T1 - Block copolymers of poly(vinylidene fluoride) obtained via 1,3 dipolar cycloaddition T2 - Abstracts of papers : joint conference / The Chemical Institute of Cananda, CIC, American Chemical Society, ACS Y1 - 2011 SN - 0065-7727 VL - 242 PB - American Chemical Society CY - Washington ER - TY - CHAP A1 - Ramadan, Shahenda A1 - Guerrero, Paula A1 - Nedielkov, Ruslan A1 - Klishin, Nikolai A1 - Dimova, Rumiana A1 - Silva, Daniel V. A1 - Möller, Heiko T1 - Building a mimetic system for unraveling protein-protein interactions on membranes T2 - European biophysics journal : with biophysics letters ; an international journal of biophysics Y1 - 2021 U6 - https://doi.org/10.1007/s00249-021-01558-w SN - 0175-7571 SN - 1432-1017 VL - 50 IS - SUPPL 1 SP - S153 EP - S153 PB - Springer CY - Berlin ; Heidelberg ; New York ER - TY - CHAP A1 - Sharkovska, Y. A1 - Pohl, K. K. A1 - Hocher, Berthold A1 - Dschietzig, T. T1 - Cardiac expression of relaxin and its receptor RXFP1 in rats with renovascular hypertension T2 - EUROPEAN HEART JOURNAL Y1 - 2013 SN - 0195-668X SN - 1522-9645 VL - 34 IS - 10 SP - 1056 EP - 1056 PB - OXFORD UNIV PRESS CY - OXFORD ER - TY - CHAP A1 - Völler, Heinz A1 - Salzwedel, Annett A1 - Reibis, Rona Katharina A1 - Eichler, Sarah A1 - Buhlert, Hermann A1 - Kaminski, Stefan A1 - Wegscheider, Karl T1 - Cardiopulmonary exercise testing is predictive of return to work in cardiac patients after multicomponent rehabilitation T2 - European heart journal Y1 - 2015 SN - 0195-668X SN - 1522-9645 VL - 36 SP - 635 EP - 636 PB - Oxford Univ. Press CY - Oxford ER - TY - CHAP A1 - Völler, Heinz A1 - Eichler, Sarah A1 - Harnath, Axel A1 - Kamke, Wolfram A1 - Butter, Christian A1 - Kraehe, Mathias A1 - Schikora, Martin A1 - Jachczyk, J. A1 - Salzwedel, Annett T1 - Case management in patients after TAVI: are frailty and exercise capacitiy predictors for decision making process? T2 - European heart journal Y1 - 2015 SN - 0195-668X SN - 1522-9645 VL - 36 SP - 635 EP - 635 PB - Oxford Univ. Press CY - Oxford ER - TY - CHAP A1 - Wippert, Pia-Maria A1 - De Witt Huberts, Jessie A1 - Honold, Jasmin A1 - Holzmann, Caroline A1 - Rector, Michael V. A1 - Mayer, Frank T1 - Chronic stress measurement methods and their comparability T2 - Psychosomatic medicine Y1 - 2014 SN - 0033-3174 SN - 1534-7796 VL - 76 IS - 3 SP - A129 EP - A129 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Trukenbrod, Hans Arne A1 - Barthelme, S. A1 - Wichmann, Felix A. A1 - Engbert, Ralf T1 - Color does not guide eye movements: Evidence from a gaze-contingent experiment T2 - PERCEPTION Y1 - 2012 SN - 0301-0066 SN - 1468-4233 VL - 41 SP - 88 EP - 88 PB - PION LTD CY - LONDON ER - TY - CHAP A1 - Krasnova, Hanna A1 - Gundlach, Jana A1 - Baumann, Annika T1 - Coming back for more BT - the effect of news feed serendipity on social networking site sage T2 - PACIS 2022 proceedings N2 - Recent spikes in social networking site (SNS) usage times have launched investigations into reasons for excessive SNS usage. Extending research on social factors (i.e., fear of missing out), this study considers the News Feed setup. More specifically, we suggest that the order of the News Feed (chronological vs. algorithmically assembled posts) affects usage behaviors. Against the background of the variable reward schedule, this study hypothesizes that the different orders exert serendipity differently. Serendipity, termed as unexpected lucky encounters with information, resembles variable rewards. Studies have evidenced a relation between variable rewards and excessive behaviors. Similarly, we hypothesize that order-induced serendipitous encounters affect SNS usage times and explore this link in a two-wave survey with an experimental setup (users using either chronological or algorithmic News Feeds). While theoretically extending explanations for increased SNS usage times by considering the News Feed order, practically the study will offer recommendations for relevant stakeholders. Y1 - 2022 UR - https://aisel.aisnet.org/pacis2022/271 SN - 9781958200018 PB - AIS Electronic Library (AISeL) CY - [Erscheinungsort nicht ermittelbar] ER - TY - CHAP A1 - Kang, Y. A1 - Barbirz, Stefanie A1 - Lipowsky, Reinhard A1 - Santer, Mark T1 - Conformational Insights into Recognition Mechanism of O-Antigen Polysaccharides by Tailspike Protein T2 - European biophysics journal : with biophysics letters ; an international journal of biophysics Y1 - 2013 SN - 0175-7571 SN - 1432-1017 VL - 42 IS - 1 SP - S112 EP - S112 PB - Springer CY - New York ER - TY - CHAP A1 - Risch, Lucie A1 - Cassel, Michael A1 - Messerschmidt, Janin A1 - Intziegianni, Konstantina A1 - Mayer, Frank T1 - Consistency and reliability of examining intratendinous blood flow in Achilles tendinopathy patients using doppler ultrasonography T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2014 SN - 0195-9131 SN - 1530-0315 VL - 46 IS - 5 SP - 46 EP - 46 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Khalil, Mahomound A1 - Isalm, K. Shaiful A1 - Raila, Jens A1 - Schenk, R. A1 - Rawel, Harshadrai Manilal A1 - Schweigert, Florian J. T1 - Content of lutein and lutein ester in tagetes and improvement of their stability T2 - Annals of nutrition & metabolism : journal of nutrition, metabolic diseases and dietetics ; an official journal of International Union of Nutritional Sciences (IUNS) KW - lutein ester KW - Emulsion KW - MCT oil KW - Stability KW - UV light Y1 - 2011 SN - 0250-6807 VL - 58 IS - 3 SP - 16 EP - 16 PB - Karger CY - Basel ER - TY - CHAP A1 - Grum, Marcus ED - Shishkov, Boris T1 - Context-aware, intelligent musical instruments for improving knowledge-intensive business processes T2 - Business modeling and software design N2 - With shorter song publication cycles in music industries and a reduced number of physical contact opportunities because of disruptions that may be an obstacle for musicians to cooperate, collaborative time consumption is a highly relevant target factor providing a chance for feedback in contemporary music production processes. This work aims to extend prior research on knowledge transfer velocity by augmenting traditional designs of musical instruments with (I) Digital Twins, (II) Internet of Things and (III) Cyber-Physical System capabilities and consider a new type of musical instrument as a tool to improve knowledge transfers at knowledge-intensive forms of business processes. In a design-science-oriented way, a prototype of a sensitive guitar is constructed as information and cyber-physical system. Findings show that this intelligent SensGuitar increases feedback opportunities. This study establishes the importance of conversion-specific music production processes and novel forms of interactions at guitar playing as drivers of high knowledge transfer velocities in teams and among individuals. KW - business process KW - knowledge transfer KW - CPS KW - prototype Y1 - 2022 SN - 978-3-031-11509-7 SN - 978-3-031-11510-3 U6 - https://doi.org/10.1007/978-3-031-11510-3_5 VL - 453 SP - 69 EP - 88 PB - Springer CY - Cham ER - TY - CHAP A1 - Schneider, Ulrike T1 - Contextualizing Jewish American Literature T2 - "Minor minorities" and multiculturalism : Italian American and Jewish American literature Y1 - 2022 SN - 978-88-6056-777-2 SN - 978-88-6056-778-9 U6 - https://doi.org/10.13138/iaam_60567789 SN - 2974-5225 SP - 331 EP - 340 PB - Eum CY - Macerata ER - TY - CHAP A1 - Rieskamp, Jonas A1 - Mirbabaie, Milad A1 - Hofeditz, Lennart A1 - Vischedyk, Justin T1 - Conversational agents and their influence on the well-being of cliniciansclinicians T2 - ACIS 2023 proceedings N2 - An increasing number of clinicians (i.e., nurses and physicians) suffer from mental health-related issues like depression and burnout. These, in turn, stress communication, collaboration, and decision- making—areas in which Conversational Agents (CAs) have shown to be useful. Thus, in this work, we followed a mixed-method approach and systematically analysed the literature on factors affecting the well-being of clinicians and CAs’ potential to improve said well-being by relieving support in communication, collaboration, and decision-making in hospitals. In this respect, we are guided by Brigham et al. (2018)’s model of factors influencing well-being. Based on an initial number of 840 articles, we further analysed 52 papers in more detail and identified the influences of CAs’ fields of application on external and individual factors affecting clinicians’ well-being. As our second method, we will conduct interviews with clinicians and experts on CAs to verify and extend these influencing factors. KW - conversational agents KW - well-being KW - mental health KW - hospitals KW - clinicians Y1 - 2023 UR - https://aisel.aisnet.org/acis2023/66 PB - Australasian Association for Information Systems CY - Wellington ER - TY - CHAP A1 - Heilmann, Katja A1 - Wand, Inga A1 - Holzlöhner, Pamela A1 - Micheel, Burkhard T1 - Cooperation of dendritic cells with naive lymphocyte populations to induce the generation of antigen-specific antibodies in vitro T2 - The journal of immunology Y1 - 2012 SN - 0022-1767 VL - 188 IS - 6 PB - American Assoc. of Immunologists CY - Bethesda ER - TY - CHAP A1 - Abramova, Olga A1 - Batzel, Katharina A1 - Modesti, Daniela T1 - Coping and regulatory responses on social media during health crisis BT - a large-scale analysis T2 - Proceedings of the 55th Hawaii International Conference on System Sciences N2 - During a crisis event, social media enables two-way communication and many-to-many information broadcasting, browsing others’ posts, publishing own content, and public commenting. These records can deliver valuable insights to approach problematic situations effectively. Our study explores how social media communication can be analyzed to understand the responses to health crises better. Results based on nearly 800 K tweets indicate that the coping and regulation foci framework holds good explanatory power, with four clusters salient in public reactions: 1) “Understanding” (problem-promotion); 2) “Action planning” (problem-prevention); 3) “Hope” (emotion-promotion) and 4) “Reassurance” (emotion-prevention). Second, the inter-temporal analysis shows high volatility of topic proportions and a shift from self-centered to community-centered topics during the course of the event. The insights are beneficial for research on crisis management and practicians who are interested in large-scale monitoring of their audience for well-informed decision-making. KW - Digital-Enabled Human-Information Interaction KW - big data KW - data mining KW - health crisis KW - social media Y1 - 2022 SN - 978-0-9981331-5-7 PB - HICSS Conference Office University of Hawaii at Manoa CY - Honolulu ER - TY - CHAP A1 - Bender, Benedict A1 - Gronau, Norbert T1 - Coring on Digital Platforms BT - Fundamentals and Examples from the Mobile Device Sector T2 - Proceedings of the 38th International Conference on Information Systems (ICIS) N2 - Today’s mobile devices are part of powerful business ecosystems, which usually involve digital platforms. To better understand the complex phenomenon of coring and related dynamics, this paper presents a case study comparing iMessage as part of Apple’s iOS and WhatsApp. Specifically, it investigates activities regarding platform coring, as the integration of several functionalities provided by third-party applications in the platform core. The paper makes three contributions. First, a systematization of coring activities is developed. Coring modes are differentiated by the amount of coring and application maintenance. Second, the case study revealed that the phenomenon of platform coring is present on digital platforms for mobile devices. Third, the fundamentals of coring are discussed as a first step towards theoretical development. Even though coring constitutes a potential threat for third-party developers regarding their functional differentiation, an idea of what a beneficial partnership incorporating coring activities could look like is developed here. KW - Coring KW - Digital Platforms KW - Digital Marketplaces KW - Mobile Software Ecosystems Y1 - 2017 UR - https://aisel.aisnet.org/icis2017/DigitalPlatforms/Presentations/6/ SN - 978-0-9966831-5-9 IS - 8 SP - 5256 EP - 5274 PB - Association for Information Systems (AIS) CY - Atlanta ER - TY - CHAP A1 - Engel, Tilman A1 - Kopinski, Stephan A1 - Carlsohn, Anja A1 - Cassel, Michael A1 - Mayer, Frank T1 - Correlation of sonographic subcutaneous adipose tissue measurements with air displacement plethysmography and calipermetry T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2014 SN - 0195-9131 SN - 1530-0315 VL - 46 IS - 5 SP - 539 EP - 539 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Natek, M. A1 - Lüth, Anja A1 - Kleuser, Burkhard A1 - Schäfer-Korting, M. A1 - Weindl, G. T1 - CpG-oligonucleotides modulate sphingosine-1-phosphate metabolism in normal human keratinocytes T2 - The journal of investigative dermatology Y1 - 2012 SN - 0022-202X VL - 132 IS - 5 SP - S112 EP - S112 PB - Nature Publ. Group CY - New York ER - TY - CHAP A1 - Hagemann, Linus A1 - Abramova, Olga T1 - Crafting audience engagement in social media conversations BT - evidence from the U.S. 2020 presidential elections T2 - Proceedings of the 55th Hawaii International Conference on System Sciences N2 - Observing inconsistent results in prior studies, this paper applies the elaboration likelihood model to investigate the impact of affective and cognitive cues embedded in social media messages on audience engagement during a political event. Leveraging a rich dataset in the context of the 2020 U.S. presidential elections containing more than 3 million tweets, we found the prominence of both cue types. For the overall sample, positivity and sentiment are negatively related to engagement. In contrast, the post-hoc sub-sample analysis of tweets from famous users shows that emotionally charged content is more engaging. The role of sentiment decreases when the number of followers grows and ultimately becomes insignificant for Twitter participants with a vast number of followers. Prosocial orientation (“we-talk”) is consistently associated with more likes, comments, and retweets in the overall sample and sub-samples. KW - mediated conversation KW - big data KW - engagement KW - sentiment analysis KW - social media Y1 - 2022 SN - 978-0-9981331-5-7 SP - 3222 EP - 3231 PB - HICSS Conference Office University of Hawaii at Manoa CY - Honolulu ER - TY - CHAP A1 - Glaschke, Christian A1 - Gronau, Norbert A1 - Bender, Benedict T1 - Cross-System Process Mining using RFID Technology T2 - Proceedings of the Sixth International Symposium on Business Modeling and Software Design - BMSD N2 - In times of digitalization, the collection and modeling of business processes is still a challenge for companies. The demand for trustworthy process models that reflect the actual execution steps therefore increases. The respective kinds of processes significantly determine both, business process analysis and the conception of future target processes and they are the starting point for any kind of change initiatives. Existing approaches to model as-is processes, like process mining, are exclusively focused on reconstruction. Therefore, transactional protocols and limited data from a single application system are used. Heterogeneous application landscapes and business processes that are executed across multiple application systems, on the contrary, are one of the main challenges in process mining research. Using RFID technology is hence one approach to close the existing gap between different application systems. This paper focuses on methods for data collection from real world objects via RFID technology and possible combinations with application data (process mining) in order to realize a cross system mining approach. KW - Process Mining KW - RFID KW - Production KW - Cross-System Y1 - 2016 SN - 978-989-758-190-8 U6 - https://doi.org/10.5220/0006223501790186 SP - 179 EP - 186 PB - SCITEPRESS - Science and Technology Publications CY - Setúbal ER - TY - CHAP ED - Radeva-Bork, Teodora ED - Kosta, Peter T1 - Current developments in Slavic linguistics - twenty years after BT - based on selected papers from FDSL 11 T2 - Potsdam linguistic investigations N2 - The book offers a comprehensive overview of current research in Slavic linguistics from a theoretical and experimental perspective and from a variety of languages. The selected papers from the 11th European Conference on Formal Description of Slavic Languages (FDSL 11) that took place at the University of Potsdam in 2015, illustrate the advancement of Slavic linguistic studies and their outreach for the development of general linguistics. The guest paper by Noam Chomsky at the beginning of the book sets a clear sign in this direction and may be taken as an acknowledgement of the field. Y1 - 2020 SN - 978-3-631-67673-8 SN - 978-3-631-70974-0 SN - 978-3-631-70975-7 SN - 978-3-6530-7147-4 U6 - https://doi.org/10.3726/978-3-653-07147-4 SN - 1862-524X VL - 29 PB - Peter Lang CY - Berlin ER - TY - CHAP A1 - Gronau, Norbert A1 - Weber, Edzard A1 - Heinze, Priscilla T1 - Cyclic process model transformation T2 - Proceedings of the 12th European Conference on Knowledge Management N2 - Process analysis usually focuses only on single and selected processes. It is either existent processes that are recorded and analysed or reference processes that are implemented. So far no evident effort has been put into generalising specific process aspects into patterns and comparing those patterns with regard to their efficiency and effectiveness. This article focuses on the combination of dynamic and holistic analytical elements in enterprise architectures. Our goal is to outline an approach to analyse the development of business processes in a cyclical matter and demonstrate this approach based on an existent modelling language. We want to show that organisational learning can derive from the systematic analysis of past and existent processes from which patterns of successful problem solving can be deducted. Y1 - 2011 SN - 978-1-908272-09-6 IS - 2 SP - 349 EP - 359 PB - Academic Conferences Ltd. CY - Reading ER - TY - CHAP A1 - Lass, Sander A1 - Bender, Benedict T1 - Dedicated Data Sovereignty as Enabler for Platform-Based Business Models T2 - Proceedings of the 2. Conference on Production Systems and Logistics N2 - The digitalization of value networks holds out the prospect of many advantages for the participating compa- nies. Utilizing information platforms, cross-company data exchange enables increased efficiency of collab- oration and offers space for new business models and services. In addition to the technological challenges, the fear of know-how leakage appears to be a significant roadblock that hinders the beneficial realization of new business models in digital ecosystems. This paper provides the necessary building blocks of digital participation and, in particular, classifies the issue of trust creation within it as a significant success factor. Based on these findings, it presents a solution concept that, by linking the identified building blocks, offers the individual actors of the digital value network the opportunity to retain sovereignty over their data and know-how and to use the potential of extensive networking. In particular, the presented concept takes into account the relevant dilemma, that every actor (e. g. the machine users) has to be able to control his commu- nicated data at any time and have sufficient possibilities for intervention that, on the one hand, satisfy the need for protection of his knowledge and, on the other hand, do not excessively diminish the benefits of the system or the business. Taking up this perspective, this paper introduces dedicated data sovereignty and shows a possible implementation concept. KW - information gateway KW - data security KW - information flow control KW - platform acceptance Y1 - 2021 U6 - https://doi.org/10.15488/11299 SP - 382 EP - 393 PB - publish-Ing. CY - Hannover ER - TY - CHAP A1 - Panzer, Marcel A1 - Bender, Benedict A1 - Gronau, Norbert T1 - Deep reinforcement learning in production planning and control BT - A systematic literature review T2 - Proceedings of the Conference on Production Systems and Logistics N2 - Increasingly fast development cycles and individualized products pose major challenges for today's smart production systems in times of industry 4.0. The systems must be flexible and continuously adapt to changing conditions while still guaranteeing high throughputs and robustness against external disruptions. Deep rein- forcement learning (RL) algorithms, which already reached impressive success with Google DeepMind's AlphaGo, are increasingly transferred to production systems to meet related requirements. Unlike supervised and unsupervised machine learning techniques, deep RL algorithms learn based on recently collected sensor- and process-data in direct interaction with the environment and are able to perform decisions in real-time. As such, deep RL algorithms seem promising given their potential to provide decision support in complex environments, as production systems, and simultaneously adapt to changing circumstances. While different use-cases for deep RL emerged, a structured overview and integration of findings on their application are missing. To address this gap, this contribution provides a systematic literature review of existing deep RL applications in the field of production planning and control as well as production logistics. From a performance perspective, it became evident that deep RL can beat heuristics significantly in their overall performance and provides superior solutions to various industrial use-cases. Nevertheless, safety and reliability concerns must be overcome before the widespread use of deep RL is possible which presumes more intensive testing of deep RL in real world applications besides the already ongoing intensive simulations. KW - deep reinforcement learning KW - machine learning KW - production planning KW - production control KW - systematic literature review Y1 - 2021 U6 - https://doi.org/10.15488/11238 SN - 2701-6277 SP - 535 EP - 545 PB - publish-Ing. CY - Hannover ER - TY - CHAP A1 - Tidball, Andrew M. A1 - Kumar, Kevin K. A1 - Bryan, Miles R. A1 - Bichell, Terry Jo A1 - Horning, Kyle A1 - Uhouse, Michael A. A1 - Goodwin, Cody R. A1 - Bornhorst, Julia A1 - Schwerdtle, Tanja A1 - Neely, Maja Diana A1 - McClean, John A. A1 - Aschner, Michael A. A1 - Bowman, Aaron B. T1 - Deficits in neural responses to manganese exposure in Huntington's disease models T2 - Neurotoxicology and teratology Y1 - 2015 U6 - https://doi.org/10.1016/j.ntt.2015.04.022 SN - 0892-0362 SN - 1872-9738 VL - 49 SP - 105 EP - 105 PB - Elsevier CY - Oxford ER - TY - CHAP A1 - Gerecke, Christian A1 - Scholtka, Bettina T1 - Detection of low level adenomatous polyposis coli(APC) gene mutatons by wild-type blocking-pcr and high resolution melting analysis T2 - Clinical chemistry and laboratory medicine : journal of the Forum of the European Societies of Clinical Chemistry - the European Branch of the International Federation of Clinical Chemistry and Laboratory Medicine Y1 - 2011 SN - 1434-6621 VL - 49 IS - 1 SP - S603 EP - S603 PB - De Gruyter CY - Berlin ER - TY - CHAP A1 - Gronau, Norbert A1 - Grum, Marcus A1 - Bender, Benedict T1 - Determining the optimal level of autonomy in cyber-physical production systems T2 - IEEE 14th International Conference on Industrial Informatics (INDIN) N2 - Traditional production systems are enhanced by cyber-physical systems (CPS) and Internet of Things. A kind of next generation systems, those cyber-physical production systems (CPPS) are able to raise the level of autonomy of its production components. To find the optimal degree of autonomy in a given context, a research approach is formulated using a simulation concept. Based on requirements and assumptions, a cyber-physical market is modeled and qualitative hypotheses are formulated, which will be verified with the help of the CPPS of a hybrid simulation environment. KW - cyber-physical systems KW - hybrid simulation KW - Internet of Things KW - manufacturing systems KW - production engineering computing KW - cyber-physical production systems Y1 - 2017 U6 - https://doi.org/10.1109/INDIN.2016.7819367 SP - 1293 EP - 1299 PB - IEEE CY - New York ER - TY - CHAP A1 - Risius, Marten A1 - Baumann, Annika A1 - Krasnova, Hanna T1 - Developing a new paradigm BT - introducing the intention-behaviour gap to the privacy paradox phenomenon T2 - Proceedings of the 28th European Conference on Information Systems (ECIS) : ECIS 2020 Research Papers N2 - Internet users commonly agree that it is important for them to protect their personal data. However, the same users readily disclose their data when requested by an online service. The dichotomy between privacy attitude and actual behaviour is commonly referred to as the “privacy paradox”. Over twenty years of research were not able to provide one comprehensive explanation for the paradox and seems even further from providing actual means to overcome the paradox. We argue that the privacy paradox is not just an instantiation of the attitude-behaviour gap. Instead, we introduce a new paradigm explaining the paradox as the result of attitude-intention and intentionbehaviour gaps. Historically, motivational goal-setting psychologists addressed the issue of intentionbehaviour gaps in terms of the Rubicon Model of Action Phases and argued that commitment and volitional strength are an essential mechanism that fuel intentions and translate them into action. Thus, in this study we address the privacy paradox from a motivational psychological perspective by developing two interventions on Facebook and assess whether the 287 participants of our online experiment actually change their privacy behaviour. The results demonstrate the presence of an intentionbehaviour gap and the efficacy of our interventions in reducing the privacy paradox. KW - privacy paradox KW - intention-behaviour gap KW - attitude-behaviour gap KW - commitment KW - rubicon model KW - social media Y1 - 2020 UR - https://aisel.aisnet.org/ecis2020_rp/150 UR - https://www.researchgate.net/publication/341507497_Developing_a_New_Paradigm_Introducing_the_Intention-Behaviour_Gap_to_the_Privacy_Paradox_Phenomenon/link/5ec4a1c892851c11a8778d3f/download?_tp=eyJjb250ZXh0Ijp7InBhZ2UiOiJwdWJsaWNhdGlvbiIsInByZXZpb3VzUGFnZSI6bnVsbH19 PB - AIS Electronic Library (AISeL) CY - [Erscheinungsort nicht ermittelbar] ER - TY - CHAP A1 - Richter, M. A1 - Fairhall, Emma A. A1 - Hoffmann, S. A. A1 - Frühwald, J. A1 - Wright, Matthew C. A1 - Zeilinger, Katrin T1 - Dexamethasone induced hepatic differentiation of rat pancreatic progenitor cells (B-13) in a 3D multicompartment bioreactor system T2 - Journal of hepatology Y1 - 2013 SN - 0168-8278 VL - 58 IS - 1 SP - S416 EP - S416 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Graffmann-Weschke, Katharina A1 - Paelecke, Annegret ED - Hochhaus, Andreas T1 - Die Rolle von Krebserkrankungen bei der Langzeitpflege durch Angehörige BT - 34. Deutscher Krebskongress informativ. innovativ. integrativ. Optimale Versorgung für alle. Berlin, 19.-22. Februar 2020: Abstracts T2 - Oncology Research and Treatment Y1 - 2020 SN - 978-3-318-06686-9 U6 - https://doi.org/10.1159/000506491 SN - 2296-5270 SN - 2296-5262 VL - 43 SP - 143 EP - 143 PB - Karger CY - Basel ER - TY - CHAP A1 - Carlsohn, Anja A1 - Weber, Josefine A1 - Müller, Juliane A1 - Stuwe, Anja A1 - Müller, Steffen A1 - Mayer, Frank T1 - Dietary intake to reduce body mass before competition in german judo athletes T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2012 SN - 0195-9131 VL - 44 SP - 109 EP - 109 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Otto, Christoph A1 - Scharhag-Rosenberger, Friederike A1 - Carlsohn, Anja A1 - Scharhag, Jürgen A1 - Mayer, Frank T1 - Differences in using the same supramaximal verification test protocol for treadmill and cycle ergometry T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2012 SN - 0195-9131 VL - 44 SP - 295 EP - 295 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Lausberg, H. A1 - Kazzer, Philipp A1 - Heekeren, Hauke A1 - Wartenburger, Isabell T1 - Differential cortical mechanisms underlying tool use, pantomime, and body-part-as-object use T2 - European journal of neurology : the official journal of the European Federation of Neurological Societies Y1 - 2012 SN - 1351-5101 VL - 19 IS - 9 SP - 78 EP - 78 PB - Wiley-Blackwell CY - Hoboken ER - TY - CHAP A1 - Rojahn, Marcel A1 - Gronau, Norbert T1 - Digital platform concepts for manufacturing companies BT - a review T2 - 10th International Conference on Future Internet of Things and Cloud (FiCloud) N2 - Digital Platforms (DPs) has established themself in recent years as a central concept of the Information Technology Science. Due to the great diversity of digital platform concepts, clear definitions are still required. Furthermore, DPs are subject to dynamic changes from internal and external factors, which pose challenges for digital platform operators, developers and customers. Which current digital platform research directions should be taken to address these challenges remains open so far. The following paper aims to contribute to this by outlining a systematic literature review (SLR) on digital platform concepts in the context of the Industrial Internet of Things (IIoT) for manufacturing companies and provides a basis for (1) a selection of definitions of current digital platform and ecosystem concepts and (2) a selection of current digital platform research directions. These directions are diverted into (a) occurrence of digital platforms, (b) emergence of digital platforms, (c) evaluation of digital platforms, (d) development of digital platforms, and (e) selection of digital platforms. Y1 - 2023 SN - 979-8-3503-1635-3 U6 - https://doi.org/10.1109/FiCloud58648.2023.00030 SP - 149 EP - 158 PB - IEEE CY - [Erscheinungsort nicht ermittelbar] ER - TY - CHAP A1 - Hocher, Berthold A1 - Reichetzeder, Christoph A1 - von Websky, Karoline A1 - Tsuprykov, Oleg A1 - Klein, T. T1 - Dipeptidyl peptidase-4 inhibition in a rat model of ischaemia-reperfusion injury may accelerate tubular regeneration but does not improve glomerular filtration rate T2 - Diabetologia : journal of the European Association for the Study of Diabetes (EASD) Y1 - 2014 SN - 0012-186X SN - 1432-0428 VL - 57 SP - S538 EP - S538 PB - Springer CY - New York ER - TY - CHAP A1 - Doyon, Anke A1 - Schmiedchen, Bettina A1 - Bayazit, Aysun A1 - Canpolat, Nur A1 - Duzova, Ali A1 - Kracht, Daniela A1 - Litwin, Mieczyslaw A1 - Niemirska, Anna A1 - Sozeri, Betul A1 - Zeller, Rene A1 - Ranchin, Bruno A1 - Anarat, Ali A1 - Caliskan, Salim A1 - Mir, Sevgi A1 - Melk, Anette A1 - Wühl, Elke A1 - Schweigert, Florian J. A1 - Querfeld, Uwe A1 - Schäfer, Franz T1 - Distribuion and determinants of serum vitamin d concentrations in european children with chronic kidney disease T2 - Pediatric nephrology : journal of the International Pediatric Nephrology Association Y1 - 2012 SN - 0931-041X VL - 27 IS - 9 SP - 1627 EP - 1628 PB - Springer CY - New York ER - TY - CHAP A1 - Gruber, W. A1 - Braumann, K. M. A1 - Kahlert, Daniela A1 - Brand, Ralf A1 - Schwarz, C. A1 - Staab, D. T1 - Do interavenous antibiotic therapies increase level of physical activity in CF? T2 - Pediatric pulmonology Y1 - 2011 SN - 8755-6863 IS - 3 SP - 355 EP - 355 PB - Wiley-Blackwell CY - Malden ER - TY - CHAP A1 - Abramova, Olga T1 - Does a smile open all doors? BT - understanding the impact of appearance disclosure on accommodation sharing platforms T2 - Proceedings of the 53rd Hawaii International Conference on System Sciences N2 - Online photographs govern an individual’s choices across a variety of contexts. In sharing arrangements, facial appearance has been shown to affect the desire to collaborate, interest to explore a listing, and even willingness to pay for a stay. Because of the ubiquity of online images and their influence on social attitudes, it seems crucial to be able to control these aspects. The present study examines the effect of different photographic self-disclosures on the provider’s perceptions and willingness to accept a potential co-sharer. The findings from our experiment in the accommodation-sharing context suggest social attraction mediates the effect of photographic self-disclosures on willingness to host. Implications of the results for IS research and practitioners are discussed. KW - The Sharing Economy KW - airbnb KW - online photographs KW - self-disclosure KW - sharing economy KW - social attraction Y1 - 2020 SN - 978-0-9981331-3-3 SP - 831 EP - 840 PB - HICSS Conference Office University of Hawaii at Manoa CY - Honolulu ER - TY - CHAP A1 - Nowozin, Claudia A1 - Wahnschaffe, A. A1 - Fay, Doris A1 - Pollatos, Olga A1 - Kunz, D. T1 - Does bright light interfere with fear learning? T2 - Journal of sleep research : official journal of the European Sleep Research Society Y1 - 2014 SN - 0962-1105 SN - 1365-2869 VL - 23 SP - 102 EP - 102 PB - Wiley-Blackwell CY - Hoboken ER - TY - CHAP A1 - Appiah-Dwomoh, Edem Korkor A1 - Torlak, Firdevs A1 - Engel, Tilman A1 - Stoll, Josefine A1 - Müller, Juliane A1 - Mayer, Frank T1 - Does perturbed treadmill walking lead to emg-changes of the lower extremity? T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2014 SN - 0195-9131 SN - 1530-0315 VL - 46 IS - 5 SP - 827 EP - 827 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Wernicke, Sarah A1 - Carlsohn, Anja A1 - Heydenreich, Juliane A1 - Mayer, Frank T1 - Does the copenhagen soccer test induce a repeated bout effect? - a pilot study T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2013 SN - 0195-9131 SN - 1530-0315 VL - 45 IS - 5 SP - 169 EP - 169 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Sharkovska, Y. A1 - Alter, Markus L. A1 - Reichetzeder, Christoph A1 - Tsuprykov, Oleg A1 - Klein, T. A1 - Hocher, Berthold T1 - DPP-4 inhibition with linagliptin delays the progression of diabetic nephropathy in db/db mice T2 - Diabetologia : journal of the European Association for the Study of Diabetes (EASD) Y1 - 2012 SN - 0012-186X SN - 1432-0428 VL - 55 IS - 5 SP - S20 EP - S20 PB - Springer CY - New York ER - TY - CHAP A1 - Arlt, Olga A1 - Schwiebs, Anja A1 - Pfarr, Kathrin A1 - Ranglack, Annika A1 - Bouzas, Ferreiros Nerea A1 - Schreiber, Yannick A1 - Neuber, Corinna A1 - Kleuser, Burkhard A1 - Pfeilschifter, Josef M. A1 - Radeke, Heinfried H. T1 - Dynamic interaction between sphingolipid enzymes, S1P and inflammatory cytokine regulation in dendritic cells T2 - NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY Y1 - 2014 SN - 0028-1298 SN - 1432-1912 VL - 387 SP - S91 EP - S91 PB - Springer CY - New York ER - TY - CHAP A1 - Bender, Benedict A1 - Fabian, Benjamin A1 - Lessmann, Stefan A1 - Haupt, Johannes T1 - E-Mail Tracking BT - status quo and novel countermeasures T2 - Proceedings of the 37th International Conference on Information Systems (ICIS) N2 - E-mail advertisement, as one instrument in the marketing mix, allows companies to collect fine-grained behavioural data about individual users’ e-mail reading habits realised through sophisticated tracking mechanisms. Such tracking can be harmful for user privacy and security. This problem is especially severe since e-mail tracking techniques gather data without user consent. Striving to increase privacy and security in e-mail communication, the paper makes three contributions. First, a large database of newsletter e-mails is developed. This data facilitates investigating the prevalence of e- mail tracking among 300 global enterprises from Germany, the United Kingdom and the United States. Second, countermeasures are developed for automatically identifying and blocking e-mail tracking mechanisms without impeding the user experience. The approach consists of identifying important tracking descriptors and creating a neural network-based detection model. Last, the effectiveness of the proposed approach is established by means of empirical experimentation. The results suggest a classification accuracy of 99.99%. KW - E-Mail Tracking KW - Countermeasures KW - Privacy KW - Security KW - Machine Learning Y1 - 2016 UR - https://aisel.aisnet.org/icis2016/ISSecurity/Presentations/13/ ER - TY - CHAP A1 - Fabian, Benjamin A1 - Bender, Benedict A1 - Weimann, Lars T1 - E-Mail tracking in online marketing BT - Methods, Detection, and Usage T2 - Proceedings of the 12th International Conference on Wirtschaftsinformatik N2 - E-Mail tracking uses personalized links and pictures for gathering information on user behavior, for example, where, when, on what kind of device, and how often an e-mail has been read. This information can be very useful for marketing purposes. On the other hand, privacy and security requirements of customers could be violated by tracking. This paper examines how e-mail tracking works, how it can be detected automatically, and to what extent it is used in German e-commerce. We develop a detection model and software tool in order to collect and analyze more than 600 newsletter e-mails from companies of several different industries. The results show that the usage of e-mail tracking in Germany is prevalent but also varies depending on the industry. KW - E-Mail Tracking KW - Online Marketing KW - Privacy Y1 - 2015 UR - https://aisel.aisnet.org/wi2015/74 SN - 978-3-00-049184-9 IS - 74 PB - Associations for Information Systems AIS CY - Atlanta ER - TY - CHAP A1 - Scharhag, Jürgen A1 - Hotzkow, Kristin A1 - Kopinski, Stephan A1 - Barche, Martin A1 - Mayer, Frank T1 - Echocardiographic 3d speckle tracking values on cardiac wall motion in elite adult, adolescent and pediatric athletes T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2012 SN - 0195-9131 VL - 44 SP - 241 EP - 241 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Lachmann, Sabrina C. A1 - Spijkerman, Elly A1 - Maberly, Stephen C. T1 - Ecology matters: linking inorganic carbon acquisition to ecological preference in four species of microalgae (Chlorophyceae) T2 - European journal of phycology Y1 - 2015 SN - 0967-0262 SN - 1469-4433 VL - 50 SP - 98 EP - 98 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - CHAP A1 - Nitardy, Aischa A1 - Salzwedel, Annett A1 - Wegscheider, Karl A1 - Jawari, Amir A1 - Buhlert, Hermann A1 - Völler, Heinz T1 - Effect of cardiac rehabilitation on functional and emotional status in patients after transcatheter aortic-valve replacement T2 - Circulation : an American Heart Association journal KW - Cardiac rehabilitation KW - TAVI KW - Transcatheter Aortic Valve Implantation KW - Aortic valve KW - Exercise tests Y1 - 2012 SN - 0009-7322 SN - 1524-4539 VL - 126 IS - 21 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Pfab, T. A1 - Sharkovska, Yukiya A1 - Alter, Markus L. A1 - von Websky, Karoline A1 - Mark, M. A1 - Klein, T. A1 - Hocher, Berthold T1 - Effect of linagliptin on infarction size and cardiac function in rats after myocardial ischaemia reperfusion T2 - Diabetologia : journal of the European Association for the Study of Diabetes (EASD) Y1 - 2011 SN - 0012-186X VL - 54 SP - S329 EP - S329 PB - Springer CY - New York ER - TY - CHAP A1 - Reichetzeder, Christoph A1 - von Websky, Karoline A1 - Tsuprykov, Oleg A1 - Antonenko, V. A1 - Samarin, Azin Mohagheghi A1 - Hocher, Berthold T1 - Effects of DPP-4 inhibition on glomerular and tubular function in a rat model of ischaemia-reperfusion injury T2 - Diabetologia : journal of the European Association for the Study of Diabetes (EASD) Y1 - 2015 SN - 0012-186X SN - 1432-0428 VL - 58 SP - S34 EP - S35 PB - Springer CY - New York ER - TY - CHAP A1 - Müller, Juliane A1 - Weber, Josefine A1 - Otto, Christoph A1 - Müller, Steffen A1 - Mayer, Frank T1 - Effects of six-month trunk stability exercises on low back pain prevalence in young athletes T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2012 SN - 0195-9131 VL - 44 SP - 601 EP - 601 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Schaper, K. A1 - Kietzmann, M. A1 - Kleuser, Burkhard A1 - Baeumer, W. T1 - Effects of sphingosine-1-phosphate and FTY720 on epidermal hyperproliferation and inflammation in an imiquimod induced mouse model of psoriasis T2 - NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY Y1 - 2012 SN - 0028-1298 VL - 385 IS - 3 SP - 80 EP - 80 PB - Springer CY - New York ER - TY - CHAP A1 - Ventura-Bort, Carlos A1 - Schneider, Paula A1 - Weymar, Mathias T1 - Effects of transcutaneous auricular vagus nerve stimulation (TAVNS) on interoception T2 - Psychophysiology : journal of the Society for Psychophysiological Research KW - Interoception KW - Neurostimulation KW - Heart Rate Y1 - 2021 U6 - https://doi.org/10.1111/psyp.13928 SN - 1469-8986 VL - 58 SP - S58 EP - S58 PB - Wiley-Blackwell CY - Malden, Mass. [u.a.] ER - TY - CHAP A1 - Grum, Marcus A1 - Bender, Benedict A1 - Gronau, Norbert A1 - Alfa, Attahiru S. T1 - Efficient task realizations in networked production infrastructures T2 - Proceedings of the Conference on Production Systems and Logistics N2 - As Industry 4.0 infrastructures are seen as highly evolutionary environment with volatile, and time-dependent workloads for analytical tasks, particularly the optimal dimensioning of IT hardware is a challenge for decision makers because the digital processing of these tasks can be decoupled from their physical place of origin. Flexible architecture models to allocate tasks efficiently with regard to multi-facet aspects and a predefined set of local systems and external cloud services have been proven in small example scenarios. This paper provides a benchmark of existing task realization strategies, composed of (1) task distribution and (2) task prioritization in a real-world scenario simulation. It identifies heuristics as superior strategies. KW - Industry 4.0 KW - CPS KW - Decentral Decision Making KW - Industrial Analytics KW - Case Study Y1 - 2020 U6 - https://doi.org/10.15488/9682 SP - 397 EP - 407 PB - publish-Ing. CY - Hannover ER - TY - CHAP A1 - Kiy, Alexander A1 - Grünwald, Franka A1 - Zoerner, Dietmar A1 - Lucke, Ulrike ED - Trasch, Stephan ED - Plötzner, Rolf ED - Schneider, Gerhard ED - Sassiat, Daniel ED - Gayer, Claudia ED - Wöhrle, Nicole T1 - Ein Hochschul-App-Framework: Hybrid und modular T2 - DeLFI 2014 - Die 12. e-Learning Fachtagung Informatik Lecture Notes in Informatics N2 - Mobile Endgeräte und die dazugehörigen Applikationen sind zu einem unverzichtbaren Bestandteil des täglichen Lebens geworden und ermöglichen den ortsund zeitunabhängigen Zugriff auf wichtige Informationen. Hochschulspezifische An- gebote sind im mobilen Bereich hingegen noch immer nicht flächendeckend anzutreffen und lassen sich i. d. R. nur auf Einzelaktivitäten Studierender und Lehrender zurückführen. Dabei können mobile Applikationen einen essentiellen Beitrag zur Verbesserung der studentischen Selbstorganisation sowie für die Ausgestaltung und Ergänzung von konkreten Lehr-/Lernszenarien leisten. Dieser Artikel stellt ein modulares Hochschul-App-Framework vor, das sowohl zentrale campusbezogene Dienste als auch dezentrale Lernapplikationen unter einer Oberfläche vereint anbietet. Anhand einer Analyse von Stärken und Schwächen werden verschiedene Ansätze in Hinblick auf Anforderungen, Entwicklung, Wartung und Betrieb der Hochschul-App zusammengefasst und bewertet. Es wird auf die zugrundeliegende serviceorientierte Architektur eingegangen, die eine Portierung der Applikation auf andere Hochschulen mit einem vertretbaren Aufwand ermöglicht. Der Beitrag schließt mit einer Darstellung der ersten Ergebnisse und weiterführender Überlegungen und Arbeiten. Y1 - 2014 UR - https://subs.emis.de/LNI/Proceedings/Proceedings233/article18.html SN - 978-3-88579-627-5 IS - P-233 SP - 205 EP - 216 PB - Gesellschaft für Informatik e.V. CY - Bonn ER - TY - CHAP A1 - Kiy, Alexander A1 - Strelczuk, Frederik A1 - Lucke, Ulrike ED - Horbach, Matthias T1 - Ein Plugin zur integrierten Literaturverwaltung in Moodle T2 - Ein Plugin zur integrierten Literaturverwaltung in Moodle Y1 - 2013 SN - 978-3-88579-614-5 SP - 334 EP - 345 PB - Gesellschaft für Informatik e.V. CY - Bonn ER - TY - CHAP ED - Hähnchen, Susanne T1 - Eine Methodenlehre oder viele Methoden? BT - zweites Bielefelder Kolloquium zur Methodenlehre zwischen Handwerk und Wissenschaft N2 - Die Methodenlehre ist das Grundlagenfach mit der größten Nähe zur Praxis. Dennoch bewegt sie sich oftmals auf einer hohen Abstraktionsebene und ihr Zweck wird im juristischen Alltag, im Studium oder in der Praxis nicht immer erreicht. Dominiert vom Zivil- und insbesondere Arbeitsrecht, werden Besonderheiten des Öffentlichen Rechts und des Strafrechts ebenso wenig allgemein zur Kenntnis genommen wie (wieder) aktuelle Ansätze etwa der Rechtsrhetorik, der ökonomischen Analyse und der praktischen Jurisprudenz. Es sind eher interne Diskussionen, die innerhalb der Fachdisziplinen und in den noch kleineren Kreisen der methodisch Denkenden geführt werden. Im Zentrum des Kolloquiums stand daher die Frage, ob es eine allgemeine Methodenlehre gibt oder jeweils spezifische Methoden. Ziel war es, über Generationen, Fächergrenzen und Schulen hinaus ins Gespräch zu kommen. Der Tagungsband vereint die Referate und kurzen Zusammenfassungen der anregenden Diskussionen. Y1 - 2020 SN - 978-3-16-159593-6 SN - 978-3-16-159676-6 PB - Mohr Siebeck CY - Tübingen ER - TY - CHAP A1 - Winter, Robert A1 - Bender, Benedict A1 - Aier, Stephan ED - Bui, Tung X. T1 - Enterprise-level IS research – need, conceptualization, exemplary knowledge contributions and future opportunities T2 - Proceedings of the 57th Annual Hawaii International Conference on System Sciences N2 - Enterprise solutions, specifically enterprise systems, have allowed companies to integrate enterprises’ operations throughout. The integration scope of enterprise solutions has increasingly widened, now often covering customer activities, activities along supply chains, and platform ecosystems. IS research has contributed a wide range of explanatory and design knowledge dealing with this class of IS. During the last two decades, many technological as well as managerial/organizational innovations extended the affordances of enterprise solutions—but this broader scope also challenges traditional approaches to their analysis and design. This position paper presents an enterprise-level (i.e., cross-solution) perspective on IS, discusses the challenges of complexity and coordination for IS design and management, presents selected enterprise-level insights for IS coordination and governance, and explores avenues towards a more comprehensive body of knowledge on this important level of analysis. KW - enterprise ecosystems: the integrated enterprise KW - levels of information systems research (process, enterprise-, ecosystem- & industry-level) KW - enterprise architecture KW - enterprise systems KW - is governance KW - it/business alignment KW - organizational level Y1 - 2024 SN - 978-0-9981331-7-1 SP - 6402 EP - 6411 PB - Hawaii International Conference on System Sciences CY - Honolulu, HI ER - TY - CHAP A1 - Bender, Benedict A1 - Grum, Marcus T1 - Entwicklung eines Architekturkonzepts zum flexiblen Einsatz von Analytics T2 - Proceedings INFORMATIK - Jahrestagung der Gesellschaft für Informatik e.V. ; Lecture Notes in Informatics (LNI) N2 - Die optimale Dimensionierung von IT-Hardware stellt Entscheider aufgrund der stetigen Weiterentwicklung zunehmend vor Herausforderungen. Dies gilt im Speziellen auch für Analytics-Infrastrukturen, die zunehmend auch neue Software zur Analyse von Daten einsetzen, welche in den Ressourcenanforderungen stark variieren. Damit eine flexible und gleichzeitig effiziente Gestaltung von Analytics-Infrastrukturen erreicht werden kann, wird ein dynamisch arbeitendes Architekturkonzept vorgeschlagen, das Aufgaben auf Basis einer systemspezifischen Entscheidungsmaxime mit Hilfe einer Eskalationsmatrix verteilt und hierfür Aufgabencharakteristiken sowie verfügbare Hardwareausstattungen entsprechend ihrer Auslastung berücksichtigt. KW - Analytics KW - Architekturkonzept KW - Cyber-Phsysische Systeme KW - Cloud KW - Internet of Things Y1 - 2016 UR - https://dl.gi.de/handle/20.500.12116/1189 IS - P259 SP - 815 EP - 824 PB - Gesellschaft für Informatik e.V. CY - Bonn ER - TY - CHAP ED - Gronau, Norbert ED - Heine, Moreen ED - Poustcchi, Key ED - Krasnova, Hanna T1 - Entwicklungen, Chancen und Herausforderungen der Digitalisierung BT - Proceedings der Community Tracks zur WI 2020 N2 - Stetig steigende Studierendenzahlen und Studierendenerwartungen der „Generation Z“ als „Digital Natives“ stellen Hochschulen bei gleichbleibenden Lehrressourcen vor vielfältige technische, didaktische, organisationale und curriculare Herausforderungen. Aufgrund ihrer Diversität und Heterogenität gibt es keinen einheitlichen Weg der digitalen Transformation im Hochschulsektor. Curricula, Studienstrukturen, Präsenzlehre und digitale Lehr- und Lernangebote müssen auf die jeweiligen Hochschulen, Zielgruppen und Kooperationspartner zugeschnitten werden. Dabei müssen auch neue Zielgruppen erreicht werden, z.B. Berufstätige und Teilzeitstudierende, und die Individualisierung sowie die nationale und internationale Studierendenmobilität gefördert werden. Kompetenzen für die Informationsextraktion aus Lern- und Studienprozessen, (Big) Data Analytics und Visualisierung, Künstliche Intelligenz und Augmented Reality müssen in Hochschulen aufgebaut werden. Von der digitalen Transformation sind alle Bereiche von Hochschulen betroffen, z.B. Präsidien, Fakultäten und gleichgestellte Einrichtungen, Universitätsverwaltungen, Forschungseinrichtungen sowie zentrale und dezentrale (IT-)Dienstleister, die sich mit schnell verändernden Anforderungs- und Rollenprofilen anpassen müssen. Ferner sind rechtliche Rahmenbedingungen zu betrachten, z.B. Datenschutzanforderungen, um die Potenziale von digitalen Lehr- und Lernangeboten und von digitalen Medien in der Lehre zu erschließen. Dieser Track diskutiert theoretische, konzeptionelle, gestaltungsorientierte, empirische und verhaltensorientierte Beiträge. Y1 - 2020 SN - 978-3-95545-336-7 U6 - https://doi.org/10.30844/wi_2020_ct VL - 2 PB - GITO mbH Verlag für Industrielle Informationstechnik und Organisation CY - Berlin ER - TY - CHAP A1 - Brand, Ralf A1 - Elbe, Anne M. T1 - Ethical decision-making training as a chance for doping prevention? T2 - Journal of sport & exercise psychology Y1 - 2012 SN - 0895-2779 VL - 34 SP - S205 EP - S205 PB - Human Kinetics Publ. CY - Champaign ER - TY - CHAP A1 - Démaris, Alise A1 - Grišić, Ana-Marija A1 - Huisinga, Wilhelm A1 - Walter, Reinisch A1 - Kloft, Charlotte T1 - Evaluation of dosing strategies of anti-TNF alpha monoclonal antibodies using pharmacokinetic modelling and simulation T2 - Journal of Crohn's and Colitis N2 - Background: Anti-TNFα monoclonal antibodies (mAbs) are a well-established treatment for patients with Crohn’s disease (CD). However, subtherapeutic concentrations of mAbs have been related to a loss of response during the first year of therapy1. Therefore, an appropriate dosing strategy is crucial to prevent the underexposure of mAbs for those patients. The aim of our study was to assess the impact of different dosing strategies (fixed dose or body size descriptor adapted) on drug exposure and the target concentration attainment for two different anti-TNFα mAbs: infliximab (IFX, body weight (BW)-based dosing) and certolizumab pegol (CZP, fixed dosing). For this purpose, a comprehensive pharmacokinetic (PK) simulation study was performed. Methods: A virtual population of 1000 clinically representative CD patients was generated based on the distribution of CD patient characteristics from an in-house clinical database (n = 116). Seven dosing regimens were investigated: fixed dose and per BW, lean BW (LBW), body surface area, height, body mass index and fat-free mass. The individual body size-adjusted doses were calculated from patient generated body size descriptor values. Then, using published PK models for IFX and CZP in CD patients2,3, for each patient, 1000 concentration–time profiles were simulated to consider the typical profile of a specific patient as well as the range of possible individual profiles due to unexplained PK variability across patients. For each dosing strategy, the variability in maximum and minimum mAb concentrations (Cmax and Cmin, respectively), area under the concentration-time curve (AUC) and the per cent of patients reaching target concentration were assessed during maintenance therapy. Results: For IFX and CZP, Cmin showed the highest variability between patients (CV ≈110% and CV ≈80%, respectively) with a similar extent across all dosing strategies. For IFX, the per cent of patients reaching the target (Cmin = 5 µg/ml) was similar across all dosing strategies (~15%). For CZP, the per cent of patients reaching the target average concentration of 17 µg/ml ranged substantially (52–71%), being the highest for LBW-adjusted dosing. Conclusion: By using a PK simulation approach, different dosing regimen of IFX and CZP revealed the highest variability for Cmin, the most commonly used PK parameter guiding treatment decisions, independent upon dosing regimen. Our results demonstrate similar target attainment with fixed dosing of IFX compared with currently recommended BW-based dosing. For CZP, the current fixed dosing strategy leads to comparable percentage of patients reaching target as the best performing body size-adjusted dosing (66% vs. 71%, respectively). KW - linical databases KW - crohn's disease KW - regimen KW - monoclonal antibodies KW - body surface area KW - infliximab KW - fat-free mass KW - certolizumab pegol KW - body mass index procedure Y1 - 2020 U6 - https://doi.org/10.1093/ecco-jcc/jjz203.201 SN - 1873-9946 SN - 1876-4479 VL - 14 IS - Supp. 1 SP - S171 EP - S172 PB - Oxford Univ. Press CY - Oxford ER - TY - CHAP A1 - Krasnova, Hanna A1 - große Deters, Fenne A1 - Gladkaya, Margarita T1 - Examining social media as a driver of perfectionism T2 - PACIS 2021 proceedings N2 - Perfectionism is a personality disposition characterized by setting extremely high performance-standards coupled with critical self-evaluations. Often conceived as positive, perfectionism can yield not only beneficial but also deleterious outcomes ranging from anxiety to burnout. In this proposal, we set out to investigate the role of the technology and, particularly, social media in individuals’ strivings for perfection. We lay down theoretical bases for the possibility that social media plays a role in the development of perfectionism. To empirically test the hypothesized relationship, we propose a comprehensive study design based on the experience sampling method. Lastly, we provide an overview of the planned analysis and future steps. Y1 - 2021 UR - https://aisel.aisnet.org/pacis2021/260 SN - 978-1-7336325-7-7 PB - AIS Electronic Library (AISeL) CY - [Erscheinungsort nicht ermittelbar] ER - TY - CHAP A1 - Grum, Marcus A1 - Klippert, Monika A1 - Albers, Albert A1 - Gronau, Norbert A1 - Thim, Christof T1 - Examining the quality of knowledge transfers BT - the draft of an empirical research T2 - Proceedings of the Design Society N2 - Already successfully used products or designs, past projects or our own experiences can be the basis for the development of new products. As reference products or existing knowledge, it is reused in the development process and across generations of products. Since further, products are developed in cooperation, the development of new product generations is characterized by knowledge-intensive processes in which information and knowledge are exchanged between different kinds of knowledge carriers. The particular knowledge transfer here describes the identification of knowledge, its transmission from the knowledge carrier to the knowledge receiver, and its application by the knowledge receiver, which includes embodied knowledge of physical products. Initial empirical findings of the quantitative effects regarding the speed of knowledge transfers already have been examined. However, the factors influencing the quality of knowledge transfer to increase the efficiency and effectiveness of knowledge transfer in product development have not yet been examined empirically. Therefore, this paper prepares an experimental setting for the empirical investigation of the quality of knowledge transfers. KW - knowledge management KW - new product development KW - evaluation Y1 - 2021 U6 - https://doi.org/10.1017/pds.2021.404 SN - 2732-527X VL - 1 SP - 1431 EP - 1440 PB - Cambridge University Press CY - Cambridge ER - TY - CHAP A1 - Haase, Jennifer A1 - Thim, Christof A1 - Bender, Benedict T1 - Expanding modeling notations BT - requirements for creative process modeling T2 - Business Process Management Workshops. BPM 2021 / Lecture Notes in Business Information Processing N2 - Creativity is a common aspect of business processes and thus needs a proper representation through process modeling notations. However, creative processes constitute highly flexible process elements, as new and unforeseeable outcome is developed. This presents a challenge for modeling languages. Current methods representing creative-intensive work are rather less able to capture creative specifics which are relevant to successfully run and manage these processes. We outline the concept of creative-intensive processes and present an example from a game design process in order to derive critical process aspects relevant for its modeling. Six aspects are detected, with first and foremost: process flexibility, as well as temporal uncertainty, experience, types of creative problems, phases of the creative process and individual criteria. By first analyzing what aspects of creative work modeling notations already cover, we further discuss which modeling extensions need to be developed to better represent creativity within business processes. We argue that a proper representation of creative work would not just improve the management of those processes, but can further enable process actors to more efficiently run these creative processes and adjust them to better fit to the creative needs. KW - Modeling KW - Requirements KW - Pockets of creativity KW - Creative process Y1 - 2022 SN - 978-3-030-94342-4 SN - 978-3-030-94343-1 U6 - https://doi.org/10.1007/978-3-030-94343-1_15 IS - 436 SP - 193 EP - 196 PB - Springer CY - Cham ER - TY - CHAP A1 - Günther, Oliver A1 - Winkler, Till J. T1 - Explaining the governance of software as a service applications BT - A process view T2 - Multikonferenz Wirtschaftsinformatik 2012 - Tagungsband der MKWI 2012 N2 - Defining the allocation of decision rights for enterprise applications is a crucial issue in IT governance and organization design. Today, emerging delivery models such as Software as a Service (SaaS) defy the notion of the internal IT department as the focal point of centralized governance. Recognizing the importance of this issue, we find that the phenomenon of 'SaaS governance' itself is not yet well understood. Based on two cases of SaaS adoption, we take a process-theoretic approach to investigate the complex interaction between factors that influence in the allocation of SaaS authority. The results suggest that some factors, such as the locus of initiative and the decision for SaaS, interact with absorptive capacities and determine the later mode of application governance at a very early stage. Thus, the initiative for introducing SaaS emerges as an important intermediate variable between the overall IT governance mode and the resulting SaaS governance outcome. Y1 - 2012 UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84879878424&partnerID=MN8TOARS SN - 978-3-942183-63-5 SP - 599 EP - 612 PB - Gito CY - Berlin ER - TY - CHAP A1 - Ferrolino, Mylene A1 - Zhuravleva, Anastasia A1 - Ignatova, Zoya A1 - Gierasch, Lila T1 - Exploring In vitro and in vivo aggregation of a beta-Clam protein T2 - Protein science : a publication of the Protein Society Y1 - 2012 SN - 0961-8368 VL - 21 IS - 2 SP - 89 EP - 89 PB - Wiley-Blackwell CY - Hoboken ER - TY - CHAP A1 - Batzel, Katharina A1 - Baum, Katharina T1 - Exploring information flow on twitter: social network analysis on gender-specific sedicine T2 - AMCIS Proceedings 2022 N2 - To date, sex and gender differences play only a minor role in medical research and practice, thereby putting individuals’ health at risk. Gender-specific medicine, or the practice of taking these differences into account when conducting research and treating patients so far is being discussed primarily by experts. With people increasingly using social media such as Twitter for sharing and searching for health-related information online, Twitter can potentially educate about gender-specific medicine. However, little is known about the information circulation and the structure of interactions on the Twitter network discussing this topic. Results of a network analysis show that the network exhibits a community-structure, with information exchange being limited and concentrated in silos. This indicates that there is untapped potential for acquiring new information by users through interacting with individuals outside their community. Public health officials may benefit from this insight and tailor online campaigns to enhance awareness on gender-specific medicine. Y1 - 2022 SN - 978-1-958200-00-1 IS - 1548 PB - AIS CY - Atlanta ER -