TY - JOUR A1 - Schulze, Nicole A1 - Koetz, Joachim T1 - Kinetically controlled growth of gold nanotriangles in a vesicular template phase by adding a strongly alternating polyampholyte JF - Journal of dispersion science and technology N2 - This paper is focused on the temperature-dependent synthesis of gold nanotriangles in a vesicular template phase, containing phosphatidylcholine and AOT, by adding the strongly alternating polyampholyte PalPhBisCarb. UV-vis absorption spectra in combination with TEM micrographs show that flat gold nanoplatelets are formed predominantly in the presence of the polyampholyte at 45°C. The formation of triangular and hexagonal nanoplatelets can be directly influenced by the kinetic approach, i.e., by varying the polyampholyte dosage rate at 45°C. Corresponding zeta potential measurements indicate that a temperature-dependent adsorption of the polyampholyte on the {111} faces will induce the symmetry breaking effect, which is responsible for the kinetically controlled hindered vertical and preferred lateral growth of the nanoplatelets. KW - Kinetically controlled nanocrystal growth KW - nanotriangles KW - polyampholytes Y1 - 2016 U6 - https://doi.org/10.1080/01932691.2016.1220318 SN - 0193-2691 SN - 1532-2351 VL - 38 IS - 8 SP - 1073 EP - 1078 PB - Taylor & Francis CY - Philadelphia ER - TY - JOUR A1 - Räling, Romy A1 - Hanne, Sandra A1 - Schröder, Astrid A1 - Keßler, Carla A1 - Wartenburger, Isabell T1 - Judging the animacy of words BT - The influence of typicality and age of acquisition in a semantic decision task JF - Quarterly journal of experimental psychology N2 - The age at which members of a semantic category are learned (age of acquisition), the typicality they demonstrate within their corresponding category, and the semantic domain to which they belong (living, non-living) are known to influence the speed and accuracy of lexical/semantic processing. So far, only a few studies have looked at the origin of age of acquisition and its interdependence with typicality and semantic domain within the same experimental design. Twenty adult participants performed an animacy decision task in which nouns were classified according to their semantic domain as being living or non-living. Response times were influenced by the independent main effects of each parameter: typicality, age of acquisition, semantic domain, and frequency. However, there were no interactions. The results are discussed with respect to recent models concerning the origin of age of acquisition effects. KW - Age of acquisition KW - Animacy decision KW - Semantic classification task KW - Typicality Y1 - 2017 U6 - https://doi.org/10.1080/17470218.2016.1223704 SN - 1747-0218 SN - 1747-0226 VL - 70 IS - 10 SP - 2094 EP - 2104 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Esser, Günter A1 - Reich, Stefanie A1 - Wagener, Nina A1 - Hösch, Ingrid A1 - Ihle, Wolfgang A1 - Laucht, Manfred T1 - PoKI: Potsdamer Kinder-Interview für 6- bis 12-Jährige BT - Manual Y1 - 2017 PB - Hogrefe CY - Göttingen ER - TY - JOUR A1 - Schneider, Ulrike T1 - Darstellungsweisen von Fluchtprozessen in der Gegenwartsliteratur am Beispiel von Merle Kröger und Abbas Khider sowie den Reportagen von Wolfgang Bauer und Navid Kermani JF - Argonautenschiff: Jahrbuch der Anna Seghers Gesellschaft Y1 - 2017 SN - 978-3-947215-08-9 SN - 1430-9211 VL - 25 SP - 82 EP - 92 PB - Quintus-Verlag CY - Berlin ER - TY - CHAP A1 - Hoffmann, Dierk A1 - Schwartz, Michael A1 - Wentker, Hermann ED - Hüttmann, Jens ED - von Arnim-Rosenthal, Anna T1 - Die DDR als Chance T2 - Diktatur und Demokratie im Unterricht : der Fall DDR Y1 - 2017 SN - 978-3-86331-337-1 SP - 39 EP - 53 PB - Metropol CY - Berlin ER - TY - JOUR A1 - Ventura-Bort, Carlos A1 - Dolcos, Florin A1 - Wendt, Julia A1 - Wirkner, Janine A1 - Hamm, Alfons O. A1 - Weymar, Mathias T1 - Item and source memory for emotional associates is mediated by different retrieval processes JF - Neuropsychologia : an international journal in behavioural and cognitive neuroscience N2 - Recent event-related potential (ERP) data showed that neutral objects encoded in emotional background pictures were better remembered than objects encoded in neutral contexts, when recognition memory was tested one week later. In the present study, we investigated whether this long-term memory advantage for items is also associated with correct memory for contextual source details. Furthermore, we were interested in the possibly dissociable contribution of familiarity and recollection processes (using a Remember/Know procedure). The results revealed that item memory performance was mainly driven by the subjective experience of familiarity, irrespective of whether the objects were previously encoded in emotional or neutral contexts. Correct source memory for the associated background picture, however, was driven by recollection and enhanced when the content was emotional. In ERPs, correctly recognized old objects evoked frontal ERP Old/New effects (300-500 ms), irrespective of context category. As in our previous study (Ventura-Bort et al., 2016b), retrieval for objects from emotional contexts was associated with larger parietal Old/New differences (600-800 ms), indicating stronger involvement of recollection. Thus, the results suggest a stronger contribution of recollection-based retrieval to item and contextual background source memory for neutral information associated with an emotional event. KW - event-related potentials KW - emotion KW - source memory KW - remember/know KW - old/new KW - effect Y1 - 2017 U6 - https://doi.org/10.1016/j.neuropsychologia.2017.12.015 SN - 0028-3932 SN - 1873-3514 VL - 145 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Buschmann, Jana ED - Stiller, Jurik ED - Laschke, Christin T1 - Mit Kompetenz und Freude das Singen lehren BT - singfördernde Lehrerfortbildung für grundschulunterrichtende LehrerInnen JF - Berlin-Brandenburger Beiträge zur Bildungsforschung 2017 : Herausforderungen, Befunde und Perspektiven interdisziplinärer Bildungsforschung Y1 - 2017 SN - 978-3-631-67472-7 SN - 978-3-631-71840-7 SN - 978-3-631-71841-4 SN - 978-3-631-71842-1 U6 - https://doi.org/10.3726/b10878 N1 - Tagungsband der IZBF-Nachwuchstagung "Berlin-Brandenburger Beiträge für Bildungsforschung 2015" SP - 305 PB - Peter Lang GmbH CY - Frankfurt am Main ER - TY - JOUR A1 - Hartmann, Eddie T1 - Violence BT - constructing an emerging field of sociology JF - International Journal of Conflict and Violence Y1 - 2017 U6 - https://doi.org/10.4119/UNIBI/ijcv.623 SN - 1864-1385 VL - 11 SP - 1 EP - 9 PB - Institute for Interdisciplinary Conflict and Violence Research CY - Bielefeld ER - TY - JOUR A1 - Malesza, Marta A1 - Ostaszewski, Paweł T1 - Assessing individual differences in discounting BT - construction and initial validation of the discounting inventory JF - Current psychology N2 - The purpose of the project was to develop the Discounting Inventory (DI), a measure of individual differences in delay, probability, effort, and social discounting, all related to behavioral impulsivity. Over 400 items relating to four types of discounting were generated. Next, a study followed by a series of psychometric analyses of data obtained from a group of 2843 individuals was conducted. Principal Component Analysis yielded a four-factor structure of data, reflecting the four types of discounting. The results of Confirmatory Factor Analysis showed good fit of the four-factor model to data. Through several iterations of retaining and deleting items on the basis of their component loadings, item intercorrelations, and contribution to coefficient alphas, the total number of items was reduced to 48. The final 48-item version of the inventory has satisfactory psychometric characteristics, including Cronbach's alpha and test-retest stability. In addition, significant correlations were observed between the DI and traditional discounting instruments, suggesting that the DI measures a construct similar to the behavioral discounting process. The development of the tool was based on the assumption that discounting is a personality trait. However, the present data suggest that discounting may reflect more a state than trait function. KW - scale construction KW - personality trait KW - impulsivity KW - discounting Y1 - 2017 U6 - https://doi.org/10.1007/s12144-017-9754-x SN - 1046-1310 SN - 1936-4733 VL - 39 IS - 1 SP - 207 EP - 219 PB - Springer CY - New York ER - TY - JOUR A1 - Laquai, Frederic A1 - Andrienko, Denis A1 - Deibel, Carsten A1 - Neher, Dieter T1 - Charge carrier generation, recombination, and extraction in polymer-fullerene bulk heterojunction organic solar cells JF - Elementary processes in organic photovoltaics N2 - In this chapter we review the basic principles of photocurrent generation in bulk heterojunction organic solar cells, discuss the loss channels limiting their efficiency, and present case studies of several polymer-fullerene blends. Using steady-state and transient, optical, and electrooptical techniques, we create a precise picture of the fundamental processes that ultimately govern solar cell efficiency. KW - Charge extraction KW - Charge generation KW - Charge recombination KW - Organic solar cells KW - PBT7 KW - PBTTT KW - PCPDTBT Y1 - 2026 SN - 978-3-319-28338-8 SN - 978-3-319-28336-4 U6 - https://doi.org/10.1007/978-3-319-28338-8_11 SN - 0065-3195 VL - 272 SP - 267 EP - 291 PB - Springer CY - Berlin ER - TY - JOUR A1 - Dörfler, Thomas A1 - Holzinger, Katharina A1 - Biesenbender, Jan T1 - Constitutional Dynamics in the European Union BT - Success, Failure, and Stability of Institutional Treaty Revisions JF - International Journal of Public Administration N2 - Despite high institutional hurdles for constitutional change, one observes surprisingly many EU treaty revisions. This article takes up the questions of what determines whether a treaty provision is successfully changed and why provisions are renegotiated at subsequent Intergovernmental Conferences. The article presents an institutionalist theory explaining success and renegotiation and tests the theory using all core institutional provisions by means of Qualitative Comparative Analysis. The causal analysis shows that low conflict potential of an issue is sufficient for successfully changing the treaties. Furthermore, high conflict potential of an issue and its fundamental change are sufficient for it to be renegotiated. Y1 - 2017 U6 - https://doi.org/10.1080/01900692.2017.1295267 SN - 0190-0692 SN - 1532-4265 VL - 40 IS - 14 SP - 1237 EP - 1249 PB - Taylor & Francis CY - Philadelphia ER - TY - BOOK ED - Ferrer-Maestro, Juan José ED - Kunst, Christiane ED - de la Fuente, David Hernández ED - Faber, Eike T1 - Entre los mundos T1 - Zwischen den Welten BT - homenaje a Pedro Barceló BT - Festschrift für Pedro Barceló Y1 - 2017 SN - 978-2848675787 PB - Presses universitaires de Franche-Comté CY - Besançon ER - TY - JOUR A1 - Beta, Carsten A1 - Kruse, Karsten T1 - Intracellular oscillations and waves JF - Annual review of condensed matter physics N2 - Dynamic processes in living cells are highly organized in space and time. Unraveling the underlying molecular mechanisms of spatiotemporal pattern formation remains one of the outstanding challenges at the interface between physics and biology. A fundamental recurrent pattern found in many different cell types is that of self-sustained oscillations. They are involved in a wide range of cellular functions, including second messenger signaling, gene expression, and cytoskeletal dynamics. Here, we review recent developments in the field of cellular oscillations and focus on cases where concepts from physics have been instrumental for understanding the underlying mechanisms. We consider biochemical and genetic oscillators as well as oscillations that arise from chemo-mechanical coupling. Finally, we highlight recent studies of intracellular waves that have increasingly moved into the focus of this research field. KW - self-sustained oscillations KW - biochemical oscillators KW - genetic networks KW - chemomechanical coupling KW - actin waves Y1 - 2017 SN - 978-0-8243-5008-6 U6 - https://doi.org/10.1146/annurev-conmatphys-031016-025210 SN - 1947-5454 VL - 8 SP - 239 EP - 264 PB - Annual Reviews CY - Palo Alto ER - TY - JOUR A1 - Endesfelder, Stefanie A1 - Weichelt, Ulrike A1 - Strauß, Evelyn A1 - Schlör, Anja A1 - Sifringer, Marco A1 - Scheuer, Till A1 - Bührer, Christoph A1 - Schmitz, Thomas T1 - Neuroprotection by caffeine in hyperoxia-induced neonatal brain injury JF - International journal of molecular sciences N2 - Sequelae of prematurity triggered by oxidative stress and free radical-mediated tissue damage have coined the term “oxygen radical disease of prematurity”. Caffeine, a potent free radical scavenger and adenosine receptor antagonist, reduces rates of brain damage in preterm infants. In the present study, we investigated the effects of caffeine on oxidative stress markers, anti-oxidative response, inflammation, redox-sensitive transcription factors, apoptosis, and extracellular matrix following the induction of hyperoxia in neonatal rats. The brain of a rat pups at postnatal Day 6 (P6) corresponds to that of a human fetal brain at 28–32 weeks gestation and the neonatal rat is an ideal model in which to investigate effects of oxidative stress and neuroprotection of caffeine on the developing brain. Six-day-old Wistar rats were pre-treated with caffeine and exposed to 80% oxygen for 24 and 48 h. Caffeine reduced oxidative stress marker (heme oxygenase-1, lipid peroxidation, hydrogen peroxide, and glutamate-cysteine ligase catalytic subunit (GCLC)), promoted anti-oxidative response (superoxide dismutase, peroxiredoxin 1, and sulfiredoxin 1), down-regulated pro-inflammatory cytokines, modulated redox-sensitive transcription factor expression (Nrf2/Keap1, and NFκB), reduced pro-apoptotic effectors (poly (ADP-ribose) polymerase-1 (PARP-1), apoptosis inducing factor (AIF), and caspase-3), and diminished extracellular matrix degeneration (matrix metalloproteinases (MMP) 2, and inhibitor of metalloproteinase (TIMP) 1/2). Our study affirms that caffeine is a pleiotropic neuroprotective drug in the developing brain due to its anti-oxidant, anti-inflammatory, and anti-apoptotic properties. KW - anti-oxidative response KW - caffeine KW - hyperoxia KW - oxidative stress KW - preterm infants KW - developing brain Y1 - 2017 U6 - https://doi.org/10.3390/ijms18010187 SN - 1422-0067 SN - 1661-6596 VL - 18 PB - Molecular Diversity Preservation International CY - Basel ER - TY - JOUR A1 - Park, Jaeheung A1 - Lühr, Hermann A1 - Kervalishvili, Guram A1 - Rauberg, Jan A1 - Stolle, Claudia A1 - Kwak, Young-Sil A1 - Lee, Woo Kyoung T1 - Morphology of high-latitude plasma density perturbations as deduced from the total electron content measurements onboard the Swarm constellation JF - Journal of geophysical research : A, Space physics N2 - In this study, we investigate the climatology of high-latitude total electron content (TEC) variations as observed by the dual-frequency Global Navigation Satellite Systems (GNSS) receivers onboard the Swarm satellite constellation. The distribution of TEC perturbations as a function of geographic/magnetic coordinates and seasons reasonably agrees with that of the Challenging Minisatellite Payload observations published earlier. Categorizing the high-latitude TEC perturbations according to line-of-sight directions between Swarm and GNSS satellites, we can deduce their morphology with respect to the geomagnetic field lines. In the Northern Hemisphere, the perturbation shapes are mostly aligned with the L shell surface, and this anisotropy is strongest in the nightside auroral (substorm) and subauroral regions and weakest in the central polar cap. The results are consistent with the well-known two-cell plasma convection pattern of the high-latitude ionosphere, which is approximately aligned with L shells at auroral regions and crossing different L shells for a significant part of the polar cap. In the Southern Hemisphere, the perturbation structures exhibit noticeable misalignment to the local L shells. Here the direction toward the Sun has an additional influence on the plasma structure, which we attribute to photoionization effects. The larger offset between geographic and geomagnetic poles in the south than in the north is responsible for the hemispheric difference. Y1 - 2017 U6 - https://doi.org/10.1002/2016JA023086 SN - 2169-9380 SN - 2169-9402 VL - 122 IS - 1 SP - 1338 EP - 1359 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Chujfi-La-Roche, Salim A1 - Meinel, Christoph T1 - Matching cognitively sympathetic individual styles to develop collective intelligence in digital communities JF - AI & society : the journal of human-centred systems and machine intelligence N2 - Creation, collection and retention of knowledge in digital communities is an activity that currently requires being explicitly targeted as a secure method of keeping intellectual capital growing in the digital era. In particular, we consider it relevant to analyze and evaluate the empathetic cognitive personalities and behaviors that individuals now have with the change from face-to-face communication (F2F) to computer-mediated communication (CMC) online. This document proposes a cyber-humanistic approach to enhance the traditional SECI knowledge management model. A cognitive perception is added to its cyclical process following design thinking interaction, exemplary for improvement of the method in which knowledge is continuously created, converted and shared. In building a cognitive-centered model, we specifically focus on the effective identification and response to cognitive stimulation of individuals, as they are the intellectual generators and multiplicators of knowledge in the online environment. Our target is to identify how geographically distributed-digital-organizations should align the individual's cognitive abilities to promote iteration and improve interaction as a reliable stimulant of collective intelligence. The new model focuses on analyzing the four different stages of knowledge processing, where individuals with sympathetic cognitive personalities can significantly boost knowledge creation in a virtual social system. For organizations, this means that multidisciplinary individuals can maximize their extensive potential, by externalizing their knowledge in the correct stage of the knowledge creation process, and by collaborating with their appropriate sympathetically cognitive remote peers. KW - argumentation research KW - cyber humanistic KW - cognition KW - collaboration KW - knowledge building KW - knowledge management KW - teamwork KW - virtual groups Y1 - 2017 U6 - https://doi.org/10.1007/s00146-017-0780-x SN - 0951-5666 SN - 1435-5655 VL - 35 IS - 1 SP - 5 EP - 15 PB - Springer CY - New York ER - TY - JOUR A1 - Rominger, Christian A1 - Fink, Andreas A1 - Weiss, Elisabeth M. A1 - Bosch, Jannis A1 - Papousek, Ilona T1 - Allusive thinking (remote associations) and auditory top-down inhibition skills differentially predict creativity and positive schizotypy JF - Cognitive neuropsychiatry N2 - Introduction: Positive schizotypy and creativity seem to be linked. However, the question still remains why they are related, and what may make the difference? As creative ideation is hypothesised as a dual process (association and inhibition), the propensity for remote associations might be a shared mechanism. However, positive schizotypy and creative thinking might be differentially linked to inhibition. Therefore, this study investigated a potentially overlapping feature of positive schizotypy and creativity (remote associations) as well as a potential dissociative factor (auditory inhibition). Methods: From a large screening sample, 46 participants covering a broad range of positive schizotypy were selected. Association proneness was assessed via two association tasks, auditory inhibition skill with the forced-left condition of the Dichotic Listening Test, and creative thinking by means of two creative ideation tests. Results: Positive schizotypy and creative thinking were positively associated. Both traits were linked to lower rates of common associations. However, creative thinking was associated with higher and positive schizotypy with lower inhibitory control in the auditory domain. Conclusions: While creativity and positive schizotypy shared some variance (related to remote associations), profound inhibition skills may be vital for creative performance and may coincide with lower levels of positive schizotypy. KW - Remote associations KW - allusive thinking KW - positive schizotypy KW - auditory top-down inhibition KW - creativity Y1 - 2017 U6 - https://doi.org/10.1080/13546805.2016.1278361 SN - 1354-6805 SN - 1464-0619 VL - 22 IS - 2 SP - 108 EP - 121 PB - Taylor & Francis CY - Abingdon ER - TY - JOUR A1 - Usanova, Maria E. A1 - Shprits, Yuri Y. T1 - Inner magnetosphere coupling BT - Recent advances JF - Journal of geophysical research : Space physics N2 - The dynamics of the inner magnetosphere is strongly governed by the interactions between different plasma populations that are coupled through large-scale electric and magnetic fields, currents, and wave-particle interactions. Inner magnetospheric plasma undergoes self-consistent interactions with global electric and magnetic fields. Waves excited in the inner magnetosphere from unstable particle distributions can provide energy exchange between different particle populations in the inner magnetosphere and affect the ring current and radiation belt dynamics. The ionosphere serves as an energy sink and feeds the magnetosphere back through the cold plasma outflow. The precipitating inner magnetospheric particles influence the ionosphere and upper atmospheric chemistry and affect climate. Satellite measurements and theoretical studies have advanced our understanding of the dynamics of various plasma populations in the inner magnetosphere. However, our knowledge of the coupling processes among the plasmasphere, ring current, radiation belts, global magnetic and electric fields, and plasma waves generated within these systems is still incomplete. This special issue incorporates extended papers presented at the Inner Magnetosphere Coupling III conference held 23–27 March 2015 in Los Angeles, California, USA, and includes modeling and observational contributions addressing interactions within different plasma populations in the inner magnetosphere (plasmasphere, ring current, and radiation belts), coupling between fields and plasma populations, as well as effects of the inner magnetosphere on the ionosphere and atmosphere. KW - inner magnetosphere KW - ring current KW - radiation belts KW - magnetosphere KW - ionosphere interactions KW - plasmasphere KW - solar wind Y1 - 2016 U6 - https://doi.org/10.1002/2016JA023614 SN - 2169-9380 SN - 2169-9402 VL - 122 IS - 1 SP - 102 EP - 104 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Reifegerste, Jana A1 - Meyer, Antje A1 - Zwitserlood, Pienie T1 - Inflectional complexity and experience affect plural processing in younger and older readers of Dutch and German JF - Language, cognition and neuroscience N2 - According to dual-route models of morphological processing, regular inflections can be retrieved as whole-word forms or decomposed into morphemes. Baayen, Dijkstra, and Schreuder [(1997). Singulars and plurals in Dutch: Evidence for a parallel dual-route model. Journal of Memory and Language, 37, 94–117. doi:10.1006/jmla.1997.2509] proposed a dual-route model in which singular-dominant plurals (“brides”) are decomposed, while plural-dominant plurals (“peas”) are accessed as whole-word units. We report two lexical-decision experiments investigating how plural processing is influenced by participants’ age and morphological complexity of the language (German/Dutch). For all Dutch participants and older German participants, we replicated the interaction between number and dominance reported by Baayen and colleagues. Younger German participants showed a main effect of number, indicating decomposition of all plurals. Access to stored forms seems to depend on morphological richness and experience with word forms. The data pattern fits neither full-decomposition nor full-storage models, but is compatible with dual-route models. KW - Morphological processing KW - morphological complexity KW - ageing KW - lexical decision KW - plural processing Y1 - 2016 U6 - https://doi.org/10.1080/23273798.2016.1247213 SN - 2327-3798 SN - 2327-3801 VL - 32 IS - 4 SP - 471 EP - 487 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Schubert, Marcel A1 - Frisch, Johannes A1 - Allard, Sybille A1 - Preis, Eduard A1 - Scherf, Ullrich A1 - Koch, Norbert A1 - Neher, Dieter T1 - Tuning side chain and main chain order in a prototypical donor-acceptor copolymer BT - implications for optical, electronic, and photovoltaic characteristics JF - Elementary Processes in Organic Photovoltaics N2 - The recent development of donor–acceptor copolymers has led to an enormous improvement in the performance of organic solar cells and organic field-effect transistors. Here we describe the synthesis, detailed characterisation, and application of a series of structurally modified copolymers to investigate fundamental structure–property relationships in this class of conjugated polymers. The interplay between chemical structure and optoelectronic properties is investigated. These are further correlated to the charge transport and solar cell performance, which allows us to link their chemical structure to the observed physical properties. KW - Aggregate states KW - All-polymer heterojunctions KW - Alternating copolymers KW - Ambipolar charge transport KW - Ambipolar materials KW - Backbone modifications KW - Bilayer solar cells KW - Charge separation KW - Conformational disorder KW - Crystalline phases KW - Donor-acceptor copolymers KW - Electron traps KW - Energetic disorder KW - Energy-level alignment KW - Fermi-level alignment KW - Fermi-level pinning KW - Interface dipole KW - Interlayer KW - Intrachain order KW - Intragap states KW - Microscopic morphology KW - Mobility imbalance KW - Mobility relaxation KW - Monte Carlo simulation KW - Multiple trapping model KW - Nonradiative recombination KW - OFET KW - Open-circuit voltage KW - Optoelectronic properties KW - Partially alternating copolymers KW - Photo-CELIV KW - Photocurrent KW - Photovoltaic gap KW - Polymer intermixing KW - Recombination losses KW - Spectral diffusion KW - Statistical copolymers KW - Stille-type cross-coupling KW - Structure-property relationships KW - Time-dependent mobility KW - Time-of-flight (TOF) KW - Transient photocurrent KW - Ultraviolet photoelectron spectroscopy KW - Vacuum-level alignment KW - X-ray photoelectron spectroscopy Y1 - 2016 SN - 978-3-319-28338-8 SN - 978-3-319-28336-4 U6 - https://doi.org/10.1007/978-3-319-28338-8_10 SN - 0065-3195 VL - 272 SP - 243 EP - 265 PB - Springer CY - Berlin ER - TY - JOUR A1 - Shahid, Muhammad A1 - Manchi, G. A1 - Slunsky, Pavel A1 - Naseer, O. A1 - Fatima, A. A1 - Leo, B. A1 - Raila, Jens T1 - A systemic review of existing serological possibilities to diagnose canine osteoarthritis with a particular focus on extracellular matrix proteoglycans and protein JF - Polish journal of veterinary sciences : PJVS : the journal of Committee of Veterinary Sciences of Polish Academy of Sciences and University of Warmia and Mazury in Olsztyn N2 - Extra-cellular matrix (ECM) components are important and their stabilization is significant in maintaining normal healthy joint environment. In osteoarthritis (OA), ECM components are altered and indicate disease progression. The joint ECM is composed of proteoglycans (aggrecan, perlecan,inter α-trypsin inhibitor), glycoproteins (fibronectin, lubricin, COMP) and collagen types (most abundantly collagen type II) which represent structural and functional transformation during disease advancement. ECM investigation revealed significant biomarkers of OA that could be used as a diagnostic and therapeutic tool in different canine orthopedic diseases. This review deliberates our current findings of how the components of ECM change at the molecular level during disease progression in canine OA. KW - extra-cellular matrix KW - canine osteoarthritis KW - biomarker KW - synovial fluid KW - proteomix analysis Y1 - 2017 U6 - https://doi.org/10.1515/pjvs-2017-0024 SN - 1505-1773 SN - 2300-2557 VL - 20 IS - 1 SP - 189 EP - 201 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Cuadro, Ariel A1 - von Hagen, Alexa A1 - Costa Ball, Daniel T1 - Procedural differences in the calculation of the prevalence of reading difficulties in Spanish-speaking school children T1 - Diferencias procedimentales en el cálculo de la prevalencia del retraso lector en escolares hispanoparlantes JF - Studies in psychology JF - Estudios de psicologia / Fundación Infancia y Aprendizaje N2 - The prevalence of reading difficulties (RD) reflects controversial data ranging from 3.1–3.2% to 17.5%. Possible explanations are partly based on the incidence of orthography-specific factors influencing the reading process, but also on methodological differences that hinder comparison of the reported results. For this reason, the present study aims to analyse the prevalence of RD in a sample of 1,408 Spanish-speaking school children by comparing different ways of calculating the prevalence rate. The results reflect a prevalence of 2.2−5.3%, consistent with data reported for predominantly transparent orthographies. Some of the procedures used to identify RD are more accurate in early school years than at more advanced moments of schooling. Furthermore, the consideration of students’ sex when calculating the prevalence of RD seems to represent a more sensitive way of identifying students with RD. N2 - La prevalencia del retraso lector (RL) refleja datos controvertidos, que varían desde el 3.1–3.2% al 17.5%. Posibles explicaciones se basan en parte en la incidencia de factores específicos de cada ortografía en el proceso de lectura, pero por otra parte en diferencias metodológicas, que dificultan la comparación de los resultados informados. Por lo tanto, el presente estudio propone analizar la prevalencia del RL en una misma muestra de 1,408 escolares hispanoparlantes, comparando diversas formas de calcular el índice de prevalencia. Los resultados reflejan una prevalencia del 2.2–5.3%, consistente con los datos informados para ortografías predominantemente superficiales. Algunos de los procedimientos empleados para identificar el RL resultan más precisos en los cursos escolares iniciales, que en momentos más avanzados de la escolaridad. A su vez la consideración del sexo de los alumnos a la hora de calcular la prevalencia, parecería representar una medida más sensible para identificar a alumnos con RL. KW - reader difficulties KW - dyslexia KW - prevalence KW - sex differences KW - retraso lector KW - dislexia KW - prevalencia KW - diferencias de sexo Y1 - 2017 U6 - https://doi.org/10.1080/02109395.2016.1268388 SN - 0210-9395 SN - 1579-3699 VL - 38 IS - 1 SP - 169 EP - 197 PB - Routledge, Taylor Francis Group CY - Abingdon ER - TY - JOUR A1 - Holzlöhner, Pamela A1 - Hanack, Katja T1 - Generation of murine monoclonal antibodies by hybridoma technology JF - JoVE : Video journal N2 - Monoclonal antibodies are universal binding molecules and are widely used in biomedicine and research. Nevertheless, the generation of these binding molecules is time-consuming and laborious due to the complicated handling and lack of alternatives. The aim of this protocol is to provide one standard method for the generation of monoclonal antibodies using hybridoma technology. This technology combines two steps. Step 1 is an appropriate immunization of the animal and step 2 is the fusion of B lymphocytes with immortal myeloma cells in order to generate hybrids possessing both parental functions, such as the production of antibody molecules and immortality. The generated hybridoma cells were then recloned and diluted to obtain stable monoclonal cell cultures secreting the desired monoclonal antibody in the culture supernatant. The supernatants were tested in enzyme-linked immunosorbent assays (ELISA) for antigen specificity. After the selection of appropriate cell clones, the cells were transferred to mass cultivation in order to produce the desired antibody molecule in large amounts. The purification of the antibodies is routinely performed by affinity chromatography. After purification, the antibody molecule can be characterized and validated for the final test application. The whole process takes 8 to 12 months of development, and there is a high risk that the antibody will not work in the desired test system. KW - Immunology KW - Issue 119 KW - monoclonal antibodies KW - hybridoma technology KW - myeloma cells KW - B lymphocytes KW - antigen KW - immunconjugate Y1 - 2017 U6 - https://doi.org/10.3791/54832 SN - 1940-087X IS - 119 PB - JoVE CY - Cambridge ER - TY - JOUR A1 - Groppe, Karoline A1 - Elsner, Birgit T1 - Executive function and weight status in children BT - a one-year longitudinal perspective JF - Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence N2 - There is considerable evidence for an association between obesity and impaired executive function (EF) in adolescents and adults. However, little research has examined EF in overweight or obese children. Furthermore, data on EF in underweight individuals is lacking. In addition, there is no consensus on the directionality of the relationship between Body Mass Index (BMI) and EF, and longitudinal studies are rare. Thus, the present study examined whether children differ in their performance on a battery of EF tasks depending on their weight status (underweight, normal-weight, overweight), and investigated the longitudinal cross-lagged associations between EF and BMI. Hot EF (delay of gratification, affective decision-making), cool EF (attention shifting, inhibition, working memory [WM] updating), and BMI were assessed in 1,657 German elementary-school children at two time points, approximately one year apart. Overweight children exhibited slightly poorer attention shifting, WM updating, and affective decision-making abilities as compared to normal-weight children. Unexpectedly, they did not show any deficits in inhibition or delay of gratification. EF levels of underweight children did not differ significantly from those of normal-weight children. Furthermore, poor attention shifting and enhanced affective decision-making predicted a slightly higher BMI one year later, and a higher BMI also predicted poorer attention shifting and WM updating one year later. The latter association between BMI and subsequent EF scores, however, diminished when controlling for socioeconomic status. Results indicate that hot and cool EF plays a role in the weight development of children, and might be a promising factor to address in preventive interventions. KW - Hot and cool executive function KW - Overweight KW - Underweight KW - Middle childhood KW - Longitudinal Y1 - 2015 U6 - https://doi.org/10.1080/09297049.2015.1089981 SN - 0929-7049 SN - 1744-4136 VL - 23 IS - 2 SP - 129 EP - 147 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Pan, Jinger A1 - Yan, Ming A1 - Laubrock, Jochen T1 - Perceptual span in oral reading BT - the case of Chinese JF - Scientific Studies of Reading N2 - The present study explores the perceptual span, that is, the physical extent of the area from which useful visual information is obtained during a single fixation, during oral reading of Chinese sentences. Characters outside a window of legible text were replaced by visually similar characters. Results show that the influence of window size on the perceptual span was consistent across different fixation and oculomotor measures. To maintain normal reading behavior when reading aloud, it was necessary to have information provided from three characters to the right of the fixation. Together with findings from previous research, our findings suggest that the physical size of the perceptual span is smaller when reading aloud than in silent reading. This is in agreement with previous studies in English, suggesting that the mechanisms causing the reduced span in oral reading have a common base that generalizes across languages and writing systems. Y1 - 2017 U6 - https://doi.org/10.1080/10888438.2017.1283694 SN - 1088-8438 SN - 1532-799X VL - 21 SP - 254 EP - 263 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Rector, Michael V. A1 - Intziegianni, Konstantina A1 - Müller, Steffen A1 - Mayer, Frank A1 - Cassel, Michael T1 - Reproducibility of an ankle joint rotation correction method for assessment of Achilles tendon elongation JF - Isokinetics and exercise science : official journal of the European Isokinetic Society N2 - BACKGROUND: The Achilles tendon (AT) requires optimal material and mechanical properties to function properly. Calculation of these properties depends on accurate measurement of input parameters (i.e. tendon elongation). However, the measurement of AT elongation with ultrasound during maximum voluntary isometric contraction (MVIC) is overestimated by ankle joint rotation (AJR). Methods to correct the influence of this rotation on AT elongation exist, yet their reproducibility in clinical settings is unknown. OBJECTIVE: To evaluate the test-retest reproducibility of AT elongation during MVIC after AJR correction. METHODS: Ten participants attended test and retest measurements where they performed plantar-flexion MVIC on a dynamometer. Simultaneously, ultrasound recorded AT elongation as the displacement of the medial gastrocnemius-myotendinous junction, while an electrogoniometer measured AJR. The ankle was then passively rotated to the AJR achieved during MVIC and AT elongation again determined. Elongation was corrected by subtracting this passive AT elongation from the total AT elongation during MVIC. Reproducibility was evaluated using ICC (2.1), test-retest variability (TRV, %), Bland-Altman analyses (Bias +/- LoA [1.96*SD]) and standard error of the measurement (SEM). RESULTS: Corrected AT elongation reproducibility exhibited an ICC = 0.79, SEM = 0.2 cm and TRV = 20 +/- 19%. Bias +/- LoA were determined to be 0.0 +/- 0.8 cm. CONCLUSIONS: Using this ultrasound and electrogoniometer-based method, corrected AT elongation can be assessed reproducibly. KW - Ultrasonography KW - Achilles tendon KW - reproducibility KW - isokinetic KW - ankle joint rotation Y1 - 2017 U6 - https://doi.org/10.3233/IES-160644 SN - 0959-3020 SN - 1878-5913 VL - 25 IS - 1 SP - 47 EP - 52 PB - IOS Press CY - Amsterdam ER - TY - GEN A1 - Parsons, R. D. A1 - Schüssler, F. A1 - Garrigoux, T. A1 - Balzer, A. A1 - Füssling, Matthias A1 - Hoischen, Clemens A1 - Holler, M. A1 - Mitchell, A. A1 - Pühlhofer, G. A1 - Rowell, G. A1 - Wagner, S. A1 - Bissaldi, E. A1 - Tam, P. H. T. T1 - The HESS II GRB Observation Scheme T2 - AIP conference proceedings / American Institute of Physics N2 - Gamma-ray bursts (GRBs) are some of the Universe’s most enigmatic and exotic events. However, at energies above 10 GeV their behaviour remains largely unknown. Although space based telescopes such as the Fermi-LAT have been able to detect GRBs in this energy range, their photon statistics are limited by the small detector size. Such limitations are not present in ground based gamma-ray telescopes such as the H.E.S.S. experiment, which has now entered its second phase with the addition of a large 600 m2 telescope to the centre of the array. Such a large telescope allows H.E.S.S. to access the sub 100-GeV energy range while still maintaining a large effective collection area, helping to potentially probe the short timescale emission of these events. We present a description of the H.E.S.S. GRB observation programme, summarising the performance of the rapid GRB repointing system and the conditions under which GRB observations are initiated. Additionally we will report on the GRB follow-ups made during the 2014-15 observation campaigns. Y1 - 2017 SN - 978-0-7354-1456-3 U6 - https://doi.org/10.1063/1.4968980 SN - 0094-243X SN - 1551-7616 VL - 1792 IS - 1 PB - American Institute of Physics CY - Melville ER - TY - GEN A1 - Angüner, Ekrem Oǧuzhan A1 - Aharonian, Felix A. A1 - Bordas, Pol A1 - Casanova, Sabrina A1 - Hoischen, Clemens A1 - Oya, I. A1 - Ziegler, A. T1 - HESS J1826-130 BT - a very hard gamma-Ray spectrum source in the Galactic Plane T2 - AIP conference proceedings / American Institute of Physics N2 - HESS J1826-130 is an unidentified hard spectrum source discovered by H.E.S.S. along the Galactic plane, the spectral index being Gamma = 1.6 with an exponential cut-off at about 12 TeV. While the source does not have a clear counterpart at longer wavelengths, the very hard spectrum emission at TeV energies implies that electrons or protons accelerated up to several hundreds of TeV are responsible for the emission. In the hadronic case, the VHE emission can be produced by runaway cosmic-rays colliding with the dense molecular clouds spatially coincident with the H.E.S.S. source. Y1 - 2017 SN - 978-0-7354-1456-3 U6 - https://doi.org/10.1063/1.4968928 SN - 0094-243X SN - 1551-7616 VL - 1792 IS - 1 PB - American Institute of Physics CY - Melville ER - TY - JOUR A1 - Wiese, Heike A1 - Oncu, Mehmet Tahir A1 - Bracker, Philip T1 - Verb-third-position in Turkish-German Language Contact BT - Information-structured Linearization of singular and multilingual Speakers JF - Deutsche Sprache : ds ; Zeitschrift für Theorie, Praxis, Dokumentation N2 - In present-day German we find new word order options, particularly well-known from Turkish-German bilingual speakers in the contexts of new urban dialects, which allow violations of the canonical verb-second position in independent declarative clauses. In these cases, two positions are occupied in the forefield in front of the finite verb, usually by an adverbial and a subject, which identify, at the level of information structure, frame-setter and topic, respectively. Our study investigates the influence of verbal versus language -independent information-structural preferences for this linearisation, comparing Turkish-German multilingual speakers who have grown up in Germany with monolingual German and Turkish speakers. For tasks, in which grammatical restrictions were largely minimised, the results indicate a general tendency to place verbs in a position after the frame-setter and the topic; in addition, we found language-specific influences that distinguish Turkish-German and monolingual German speakers from monolingual Turkish ones. We interpret this as evidence for an information-structural motivation for verb-third, and for a clear dominance of German for Turkish-German speakers in Germany. Y1 - 2017 SN - 0340-9341 SN - 1866-5233 VL - 45 IS - 1 SP - 31 EP - 52 PB - Erich Schmidt CY - Berlin ER - TY - JOUR A1 - Henkel, Janin A1 - Coleman, Charles Dominic A1 - Schraplau, Anne A1 - Jöhrens, Korinna A1 - Weber, Daniela A1 - Castro, Jose Pedro A1 - Hugo, Martin A1 - Schulz, Tim Julius A1 - Krämer, Stephanie A1 - Schürmann, Annette A1 - Püschel, Gerhard Paul T1 - Induction of Steatohepatitis (NASH) with Insulin Resistance in Wild-type B6 Mice by a Western-type Diet Containing Soybean Oil and Cholesterol JF - Molecular medicine N2 - Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are hepatic manifestations of the metabolic syndrome. Many currently used animal models of NAFLD/NASH lack clinical features of either NASH or metabolic syndrome such as hepatic inflammation and fibrosis (e.g., high-fat diets) or overweight and insulin resistance (e.g., methionine-choline-deficient diets), or they are based on monogenetic defects (e.g., ob/ob mice). In the current study, a Western-type diet containing soybean oil with high n-6-PUFA and 0.75% cholesterol (SOD + Cho) induced steatosis, inflammation and fibrosis accompanied by hepatic lipid peroxidation and oxidative stress in livers of C57BL/6-mice, which in addition showed increased weight gain and insulin resistance, thus displaying a phenotype closely resembling all clinical features of NASH in patients with metabolic syndrome. In striking contrast, a soybean oil-containing Western-type diet without cholesterol (SOD) induced only mild steatosis but not hepatic inflammation, fibrosis, weight gain or insulin resistance. Another high-fat diet, mainly consisting of lard and supplemented with fructose in drinking water (LAD + Fru), resulted in more prominent weight gain, insulin resistance and hepatic steatosis than SOD + Cho, but livers were devoid of inflammation and fibrosis. Although both LAD + Fru-and SOD + Cho-fed animals had high plasma cholesterol, liver cholesterol was elevated only in SOD + Cho animals. Cholesterol induced expression of chemotactic and inflammatory cytokines in cultured Kupffer cells and rendered hepatocytes more susceptible to apoptosis. In summary, dietary cholesterol in the SOD + Cho diet may trigger hepatic inflammation and fibrosis. SOD + Cho-fed animals may be a useful disease model displaying many clinical features of patients with the metabolic syndrome and NASH. KW - Nonalcoholic Steatohepatitis (NASH) KW - Typical Western Diet KW - Nonalcoholic Fatty Liver Disease (NAFLD) KW - Dietary Cholesterol KW - Kupffer Cells Y1 - 2017 U6 - https://doi.org/10.2119/molmed.2016.00203 SN - 1076-1551 SN - 1528-3658 VL - 23 SP - 70 EP - 82 PB - Feinstein Inst. for Medical Research CY - Manhasset ER - TY - JOUR A1 - Bürki-Foschini, Audrey Damaris T1 - Differences in processing times for distractors and pictures modulate the influence of distractors in picture-word interference tasks JF - Language, cognition and neuroscience N2 - In the picture-word interference paradigm, participants name pictures while ignoring a distractor word. When targets and distractors share phonemic and/or graphemic content, naming latencies are shorter than when there is no overlap between the two words. This study examines the hypothesis that the facilitation effect is modulated by differences in the time it takes participants to encode the picture name and process the distractor. Participants named pictures while ignoring distractors that either shared a phonological/orthographical syllable with the target word or were unrelated to that word. Response latencies during the naming of the distractors were collected and used as a measure of distractor processing time. The facilitation effect in picture naming was modulated by differences in response times between the picture and word naming tasks. This finding complements previous studies in showing that picture naming processes in the picture-word interference paradigm are influenced by the time course of distractor processing. KW - Picture-word interference KW - inter-individual differences KW - phonological facilitation KW - reading performance Y1 - 2016 U6 - https://doi.org/10.1080/23273798.2016.1267783 SN - 2327-3798 SN - 2327-3801 VL - 32 IS - 1 SP - 709 EP - 723 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Groth, Detlef T1 - Modeling a secular trend by Monte Carlo simulation of height biased migration in a spatial network JF - Anthropologischer Anzeiger : journal of biological and clinical anthropology ; Mitteilungsorgan der Gesellschaft für Anthropologie N2 - Background: In a recent Monte Carlo simulation, the clustering of body height of Swiss military conscripts within a spatial network with characteristic features of the natural Swiss geography was investigated. In this study I examined the effect of migration of tall individuals into network hubs on the dynamics of body height within the whole spatial network. The aim of this study was to simulate height trends. Material and methods: Three networks were used for modeling, a regular rectangular fishing net like network, a real world example based on the geographic map of Switzerland, and a random network. All networks contained between 144 and 148 districts and between 265-307 road connections. Around 100,000 agents were initially released with average height of 170 cm, and height standard deviation of 6.5 cm. The simulation was started with the a priori assumption that height variation within a district is limited and also depends on height of neighboring districts (community effect on height). In addition to a neighborhood influence factor, which simulates a community effect, body height dependent migration of conscripts between adjacent districts in each Monte Carlo simulation was used to re-calculate next generation body heights. In order to determine the direction of migration for taller individuals, various centrality measures for the evaluation of district importance within the spatial network were applied. Taller individuals were favored to migrate more into network hubs, backward migration using the same number of individuals was random, not biased towards body height. Network hubs were defined by the importance of a district within the spatial network. The importance of a district was evaluated by various centrality measures. In the null model there were no road connections, height information could not be delivered between the districts. Results: Due to the favored migration of tall individuals into network hubs, average body height of the hubs, and later, of the whole network increased by up to 0.1 cm per iteration depending on the network model. The general increase in height within the network depended on connectedness and on the amount of height information that was exchanged between neighboring districts. If higher amounts of neighborhood height information were exchanged, the general increase in height within the network was large (strong secular trend). The trend in the homogeneous fishnet like network was lowest, the trend in the random network was highest. Yet, some network properties, such as the heteroscedasticity and autocorrelations of the migration simulation models differed greatly from the natural features observed in Swiss military conscript networks. Autocorrelations of district heights for instance, were much higher in the migration models. Conclusion: This study confirmed that secular height trends can be modeled by preferred migration of tall individuals into network hubs. However, basic network properties of the migration simulation models differed greatly from the natural features observed in Swiss military conscripts. Similar network-based data from other countries should be explored to better investigate height trends with Monte Carlo migration approach. KW - secular trend KW - body height KW - simulation KW - community effect KW - Monte Carlo method KW - network Y1 - 2017 U6 - https://doi.org/10.1127/anthranz/2017/0703 SN - 0003-5548 SN - 2363-7099 VL - 74 IS - 1 SP - 81 EP - 88 PB - Schweizerbart CY - Stuttgart ER - TY - JOUR A1 - Gomula, Aleksandra A1 - Koziel, Slawomir A1 - Groth, Detlef A1 - Bielicki, Tadeusz T1 - The effect of neighboring districts on body height of Polish conscripts JF - Anthropologischer Anzeiger : journal of biological and clinical anthropology ; Mitteilungsorgan der Gesellschaft für Anthropologie N2 - The aim of the study was to investigate the correlation of heights of conscripts living in neighboring districts in Poland. The study used 10% of a nationally representative sample of 26,178 males 18.5-19.5 years old examined during the National survey of Polish conscripts conducted in 2001. The sample represented all regions and social strata of the country and included 354 different districts within 16 voivodships (provinces). Analyses were performed with the R statistical software. A small but significant correlation (0.24, p < 0.0001) was observed for height between 1st order neighboring districts. Correlations decreased with increased distances between neighboring districts, but remained significant for 7th node neighbors (0.18, p < 0.0001). Regarding voivodships (provinces), average height showed a geographical trend from the northwest (relatively tall) to the southeast (relatively short), and the correlation was stronger for first order neighboring provinces (0.796, p < 0.001). This study revealed clusters of tall people and short people, providing a support for hypothesis of the community effect in height. Small correlations between 1st order neighbors than in another country (Switzerland) may be associated with differences in geography, since in Poland there are no natural barriers (e.g., mountains) and road infrastructure is well-developed. KW - body height KW - community effect KW - Polish conscripts Y1 - 2017 U6 - https://doi.org/10.1127/anthranz/2017/0701 SN - 0003-5548 SN - 2363-7099 VL - 74 IS - 1 SP - 71 EP - 76 PB - Schweizerbart CY - Stuttgart ER - TY - JOUR A1 - Bents, Dominik A1 - Rybak, Alexander A1 - Groth, Detlef T1 - Spatial conscript body height correlation of Norwegian districts in the 19th century JF - Anthropologischer Anzeiger : journal of biological and clinical anthropology ; Mitteilungsorgan der Gesellschaft für Anthropologie N2 - Background: We investigated height of Norwegian conscripts in view of the hypothesis of a "community effect on height" using autocorrelation analysis of district heights within a time-span of 20 years at the end of the 19th century and correlations between neighboring districts at this time. Material and methods: After digitalizing available body height data of Norwegian draftees in 1877-1878, 1880 (averaged as 1878), and 1895-1897 (averaged as 1896) we calculated the magnitude of autocorrelation of body height within the same municipality at different time points. Furthermore, we generated three different neighborhood networks, (1) based on Euclidean distances, (2) a minimum spanning tree build on those distances, (3) a network founded on real world road connections. The networks were used to determine the correlation between body height of neighboring districts depending on the number of edges required to connect two municipalities. Results: The autocorrelation value for body heights was around r = 0.5 (for all p < 0.001) in the years 1878 and 1896. The correlation between neighboring districts varied in the Euclidean distance based network between 0.47 and 0.27 approximately for both years in a sorted order, descending from nearest (0-50 km) to farthest (150-200 km, for all p < 0.001). First order neighbors in the minimum spanning tree network correlation was 0.36 in 1878 and 0.42 in 1896 (for all p < 0.001). The values of neighbor correlation in the road connection based network ranged in 1878 from 0.42 (first order neighbors) to 0.17 (forth order neighbors, for all p < 0.01) and in 1896 from 0.46 (first order neighbors) to 0.12 (forth order neighbors, for all p < 0.05). Conclusion: This initial study of Norwegian conscript height data from the 19th century showed significant medium sized effects for the within district autocorrelation between 1878 and 1896 as well as medium neighborhood correlation, slightly lower in comparison to a recent study regarding Swiss conscripts. Digitalizing more data from other years in this and later time spans as well as using older road and ship connections instead of the actual road data might stabilize and improve those findings. KW - body height KW - correlation KW - Norway KW - conscripts KW - community effect on height Y1 - 2017 U6 - https://doi.org/10.1127/anthranz/2017/0700 SN - 0003-5548 SN - 2363-7099 VL - 74 IS - 1 SP - 65 EP - 69 PB - Schweizerbart CY - Stuttgart ER - TY - JOUR A1 - Arrowsmith, J. Ramon A1 - Crosby, Christopher J. A1 - Korzhenkov, Andrey M. A1 - Mamyrov, Ernest A1 - Povolotskaya, Irina A1 - Guralnik, Benny A1 - Landgraf, Angela T1 - Surface rupture of the 1911 Kebin (Chon-Kemin) earthquake, Northern Tien Shan, Kyrgyzstan JF - Seismicity, fault rupture and earthquake hazards in slowly deforming regions N2 - The 1911 Chon-Kemin (Kebin) earthquake culminated c. 30 years of remarkable earthquakes in the northern Tien Shan (Kyrgyzstan and Kazakhstan). Building on prior mapping of the event, we traced its rupture in the field and measured more than 50 offset landforms. Cumulative fault rupture length is >155-195 km along 13 fault patches comprising six sections. The patches are separated by changes of dip magnitude or dip direction, or by 4-10 km-wide stepovers. One <40 km section overlaps and is parallel to the main north-dipping rupture but is 7 km north and dips opposite (south). Both ends of the rupture are along mountain front thrust faults demonstrating late Quaternary activity. We computed the moment from each fault patch using the surface fault traces, dip inferred from the traces, 20 km seismogenic thickness, rigidity of 3.3 x 10(10) N m(-2) and dip slip converted from our observations of the largely reverse sense of motion vertical offsets. The discontinuous patches with c. 3-4 m average slip and peak slip of <14 m yield a seismic moment of 4.6 x 10(20) Nm (M-w 7.78) to 7.4 x 10(20) Nm (M-w 7.91). The majority of moment was released along the inner eastern rupture segments. This geological moment is lower by a factor of 1.5 from that determined from teleseismic data. Y1 - 2016 SN - 978-1-86239-745-3 SN - 978-1-86239-964-8 U6 - https://doi.org/10.1144/SP432.10 SN - 0305-8719 VL - 432 SP - 233 EP - 253 PB - The Geological Society CY - London ER - TY - JOUR A1 - Kübler, Simon A1 - Streich, R. A1 - Lück, Erika A1 - Hoffmann, M. A1 - Friedrich, A. M. A1 - Strecker, Manfred T1 - Active faulting in a populated low-strain setting (Lower Rhine Graben, Central Europe) identified by geomorphic, geophysical and geological analysis JF - Seismicity, fault rupture and earthquake hazards in slowly deforming regions N2 - The Lower Rhine Graben (Central Europe) is a prime example of a seismically active low-strain rift zone characterized by pronounced anthropogenic and climatic overprint of structures, and long recurrence intervals of large earthquakes. These factors render the identification of active faults and surface ruptures difficult. We investigated two fault scarps in the Lower Rhine Graben, to decipher their structural character, offset and potential seismogenic origin. Both scarps were modified by anthropogenic activity. The Hemmerich site lies c. 20 km SW of Cologne, along the Erft Fault. The Untermaubach site lies SW of Duren, where the Schafberg Fault projects into the Rur River valley. At the Hemmerich site, geomorphic and geophysical data, as well as exploratory coring reveal evidence of repeated normal faulting. Geophysical analysis and palaeoseismological excavation at the Untermaubach site reveal a complex fault zone in Holocene gravels characterized by subtle gravel deformation. Differentiation of tectonic and fluvial features was only possible with trenching, because fault structures and grain sizes of the sediments were below the resolution of the geophysical data. Despite these issues, our investigation demonstrates that valuable insight into past earthquakes and seismogenic deformation in a low-strain environment can be revealed using a multidisciplinary approach. Y1 - 2017 SN - 978-1-86239-745-3 SN - 978-1-86239-964-8 U6 - https://doi.org/10.1144/SP432.11 SN - 0305-8719 VL - 432 SP - 127 EP - 146 PB - The Geological Society CY - London ER - TY - JOUR A1 - Krüger, Frank A1 - Kulikova, Galina A1 - Landgraf, Angela T1 - Instrumental magnitude constraints for the 11 July 1889, Chilik earthquake JF - Seismicity, fault rupture and earthquake hazards in slowly deforming regions N2 - A series of large-magnitude earthquakes above 6.9 occurred in the northern Tien-Shan between 1885 and 1911. The Chilik earthquake of 11 July 1889, has been listed with a magnitude of 8.3, based on sparse macroseismic intensities, constrained by reported damage. Despite the existence of several juvenile fault scarps in the epicentral region, that are possibly associated with the 1889 earthquake, no through-going surface rupture having the dimensions expected for a magnitude 8.3 earthquake has been located - a puzzling dilemma. Could the magnitude have been overestimated? This would have major implications not only for the understanding of the earthquake series, but also for regional hazard estimates. Fortunately, a fragmentary record from an early Rebeur-Paschwitz seismometer exists for the Chilik event, recorded in Wilhelmshaven (Germany). To constrain the magnitude, we compare the late coda waves of this record with those of recent events from Central Asia, recorded on modern instruments in Germany and filtered with Rebeur-Paschwitz instrument characteristics. Additional constraints come from disturbances of historic magnetograms that exist from the Chilik and the 1911 Chon-Kemin earthquakes. Scaling of these historic records confirm a magnitude of about 8 for the 1889 Chilik earthquake, pointing towards a lower crustal contribution to the fault area. Y1 - 2017 SN - 978-1-86239-745-3 SN - 978-1-86239-964-8 U6 - https://doi.org/10.1144/SP432.8 SN - 0305-8719 VL - 432 SP - 41 EP - 72 PB - The Geological Society CY - London ER - TY - JOUR A1 - Zöller, Gert A1 - Ullah, Shahid A1 - Bindi, Dino A1 - Parolai, Stefano A1 - Mikhailova, Natalya T1 - The largest expected earthquake magnitudes in Central Asia BT - statistical inference from an earthquake catalogue with uncertain magnitudes JF - Seismicity, fault rupture and earthquake hazards in slowly deforming regions N2 - The knowledge of the largest expected earthquake magnitude in a region is one of the key issues in probabilistic seismic hazard calculations and the estimation of worst-case scenarios. Earthquake catalogues are the most informative source of information for the inference of earthquake magnitudes. We analysed the earthquake catalogue for Central Asia with respect to the largest expected magnitudes m(T) in a pre-defined time horizon T-f using a recently developed statistical methodology, extended by the explicit probabilistic consideration of magnitude errors. For this aim, we assumed broad error distributions for historical events, whereas the magnitudes of recently recorded instrumental earthquakes had smaller errors. The results indicate high probabilities for the occurrence of large events (M >= 8), even in short time intervals of a few decades. The expected magnitudes relative to the assumed maximum possible magnitude are generally higher for intermediate-depth earthquakes (51-300 km) than for shallow events (0-50 km). For long future time horizons, for example, a few hundred years, earthquakes with M >= 8.5 have to be taken into account, although, apart from the 1889 Chilik earthquake, it is probable that no such event occurred during the observation period of the catalogue. Y1 - 2017 SN - 978-1-86239-745-3 SN - 978-1-86239-964-8 U6 - https://doi.org/10.1144/SP432.3 SN - 0305-8719 VL - 432 SP - 29 EP - 40 PB - The Geological Society CY - London ER - TY - JOUR A1 - Stein, Seth A1 - Liu, Mian A1 - Camelbeeck, Thierry A1 - Merino, Miguel A1 - Landgraf, Angela A1 - Hintersberger, Esther A1 - Kübler, Simon ED - Landgraf, Angelika ED - Kübler, Simon ED - Hintersberger, Esther ED - Stein, Seth T1 - Challenges in assessing seismic hazard in intraplate Europe JF - Seismicity, fault rupture and earthquake hazards in slowly deforming regions N2 - Intraplate seismicity is often characterized by episodic, clustered and migrating earthquakes and extended after-shock sequences. Can these observations - primarily from North America, China and Australia - usefully be applied to seismic hazard assessment for intraplate Europe? Existing assessments are based on instrumental and historical seismicity of the past c. 1000 years, as well as some data for active faults. This time span probably fails to capture typical large-event recurrence intervals of the order of tens of thousands of years. Palaeoseismology helps to lengthen the observation window, but preferentially produces data in regions suspected to be seismically active. Thus the expected maximum magnitudes of future earthquakes are fairly uncertain, possibly underestimated, and earthquakes are likely to occur in unexpected locations. These issues particularly arise in considering the hazards posed by low-probability events to both heavily populated areas and critical facilities. For example, are the variations in seismicity (and thus assumed seismic hazard) along the Rhine Graben a result of short sampling or are they real? In addition to a better assessment of hazards with new data and models, it is important to recognize and communicate uncertainties in hazard estimates. The more users know about how much confidence to place in hazard maps, the more effectively the maps can be used. Y1 - 2017 SN - 978-1-86239-745-3 SN - 978-1-86239-964-8 U6 - https://doi.org/10.1144/SP432.7 SN - 0305-8719 VL - 432 SP - 13 EP - 28 PB - The Geological Society CY - London ER - TY - BOOK ED - Landgraf, Angela ED - Kübler, Simon ED - Hintersberger, Esther ED - Stein, Seth T1 - Seismicity, fault rupture and earthquake hazards in slowly deforming regions T3 - Geological Society of London : Special publications N2 - Palaeoseismic records and seismological data from continental interiors increasingly show that these areas of slow strain accumulation are more subject to seismic and associated natural hazards than previously thought. Moreover, some of our instincts developed for assessing hazards at plate boundaries might not apply here. Hence assessing hazards and drawing implications for the future is challenging, and how well it can be done heavily depends on the ability to assess the spatiotemporal distribution of past large earthquakes. This book explores some key issues in understanding hazards in slowly deforming areas. Examples include classic intraplate regions, such as Central and Northern Europe, Mongolia, Inner Mongolia, Australia, and North and South America, and regions of widely distributed strain, such as the Tien Shan Mountains in Central Asia. The papers in this volume are grouped into two sections. The first section deals with instrumental and historical earthquake data and associated hazard assessments. The second section covers methods from structural geology, palaeoseismology and tectonic geomorphology, and incorporates field evidence Y1 - 2017 UR - http://sp.lyellcollection.org/content/432/1 SN - 978-1-86239-745-3 SN - 978-1-86239-964-8 U6 - https://doi.org/10.1144/SP432 IS - 432 PB - The Geological Society CY - London ER - TY - JOUR A1 - Landgraf, Angela A1 - Kübler, Simon A1 - Hintersberger, Esther A1 - Stein, Seth T1 - Active tectonics, earthquakes and palaeoseismicity in slowly deforming continents JF - Seismicity, fault rupture and earthquake hazards in slowly deforming regions Y1 - 2016 SN - 978-1-86239-745-3 SN - 978-1-86239-964-8 U6 - https://doi.org/10.1144/SP432.13 SN - 0305-8719 VL - 432 IS - 1 SP - 1 EP - 12 PB - The Geological Society CY - London ER - TY - JOUR ED - Kleine-Vehn, Jürgen ED - Sauer, Michael T1 - Plant Hormones BT - Methods and Protocols JF - Methods in Molecular Biology N2 - This volume aims to present a representative cross-section of modern experimental approaches relevant to Plant Hormone Biology, ranging from relatively simple physiological to highly sophisticated methods. Chapters describe physiological, developmental, microscopy-based techniques, measure hormone contents, and heterologous systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. KW - phenotyping KW - four-dimensional tissue reconstruction KW - hormonal pathways KW - measure hormone contents KW - heterologous systems Y1 - 2017 SN - 978-1-4939-6467-3 SN - 978-1-4939-8210-3 SN - 978-1-4939-6469-7 U6 - https://doi.org/10.1007/978-1-4939-6469-7 SN - 1064-3745 SN - 1940-6029 IS - 1497 PB - Springer CY - New York ER - TY - GEN A1 - Kleine-Vehn, Jürgen A1 - Sauer, Michael ED - Kleine-Vehn, Jürgen ED - Sauer, Michael T1 - Preface T2 - Plant Hormones: Methods and Protocols Y1 - 2017 SN - 978-1-4939-6469-7 SN - 978-1-4939-6467-3 U6 - https://doi.org/10.1007/978-1-4939-6469-7 SN - 1064-3745 SN - 1940-6029 VL - 1497 SP - V EP - V PB - Springer CY - New York ET - 3 ER - TY - JOUR A1 - Olejko, Lydia A1 - Bald, Ilko T1 - FRET efficiency and antenna effect in multi-color DNA origami-based light harvesting systems JF - RSC Advances N2 - Artificial light harvesting complexes find applications in artificial photosynthesis, photovoltaics and light harvesting chemical sensors. They are used to enhance the absorption of light of a reaction center which is often represented by a single acceptor. Here, we present different light harvesting systems on DNA origami structures and analyze systematically the light harvesting efficiency. By changing the number and arrangement of different fluorophores (FAM as donor, Cy3 as transmitter and Cy5 as acceptor molecules) the light harvesting efficiency is optimized to create a broadband absorption and to improve the antenna effect 1 (including two energy transfer steps) from 0.02 to 1.58, and the antenna effect 2 (including a single energy transfer step) from 0.04 to 8.7, i.e. the fluorescence emission of the acceptor is significantly higher when the light-harvesting antenna is excited at lower wavelength compared to direct excitation of the acceptor. The channeling of photo energy to the acceptor proceeds by Forster Resonance Energy Transfer (FRET) and we carefully analyze also the FRET efficiency of the different light harvesting systems. Accordingly, the antenna effect can be tuned by modifying the stoichiometry of donor, transmitter and acceptor dyes, whereas the FRET efficiency is mainly governed by the spectroscopic properties of dyes and their distances. Y1 - 2017 U6 - https://doi.org/10.1039/c7ra02114c SN - 2046-2069 VL - 7 IS - 39 SP - 23924 EP - 23934 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Martinez-Ferreiro, Silvia A1 - Reyes, Andres Felipe A1 - Bastiaanse, Roelien T1 - Overcoming discourse-linking difficulties in aphasia BT - the case of clitic pronouns JF - Clinical linguistics & phonetics N2 - The present study aims to contribute to the ongoing discussion about the impact of discourse-linking deficits on the performance of individuals with aphasia by providing new data from a set of rarely investigated constructions: sentences in which a clitic pronoun coexists alongside with the full DP it agrees with. To do so, we use data of individuals with non-fluent aphasias who need to overcome the difficulties in direct object (accusative) clitic production. This results in overproduction of non-target clitic right dislocations (RDs) and clitic doubling (CD). Data from 15 individual’s native speakers of Spanish and Catalan are discussed. Data complement the results of previous investigations on discourse-linking effects in these languages, allowing the interpretation of results across constructions. KW - Clitic pronouns KW - discourse KW - aphasia KW - Spanish KW - Catalan Y1 - 0207 U6 - https://doi.org/10.1080/02699206.2017.1308015 SN - 0269-9206 SN - 1464-5076 VL - 31 IS - 6 SP - 459 EP - 477 PB - Taylor & Francis Group CY - Philadelphia ER - TY - JOUR A1 - Endrejat, Paul C. A1 - Baumgarten, Franz A1 - Kauffeld, Simone T1 - When theory meets practice BT - Combining Lewin’s Ideas about Change with Motivational Interviewing to Increase Energy-Saving Behaviours Within Organizations JF - Journal of Change Management N2 - Although more than seven decades have passed since Lewin laid the foundation for how employees’ behaviour could be changed within organizations, his ideas are far from being obsolescent. Accordingly, this article demonstrates how Lewin’s concepts can still be of use in tackling current issues (i.e. the need to raise energy-saving behaviours within organizations). In order to revive Lewin’s concepts, we combine his approaches on organization change with Motivational Interviewing (MI), a facilitation approach that fits well with his democratic and participatory mind-set. After a theoretical consideration of how Lewin’s ideas could be accompanied by MI principles, we outline a practical concept for raising the level of employees’ energy-saving behaviours to a higher standard. The usefulness of our concept is highlighted on the basis of qualitative (a force field analysis) and quantitative (an increase of energy-saving norms and – behaviours) data. Lewin’s legacy for current organization development, and the theoretical as well as practical implications for how his ideas could be applied through a combination with MI practices, are discussed. KW - Kurt Lewin KW - field theory KW - group dynamics KW - motivational interviewing KW - energy-saving KW - organization development Y1 - 2017 U6 - https://doi.org/10.1080/14697017.2017.1299372 SN - 1469-7017 SN - 1479-1811 VL - 17 IS - 2 SP - 101 EP - 120 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - GEN A1 - Kubatova, B. A1 - Kubát, Jiří A1 - Hamann, Wolf-Rainer A1 - Oskinova, Lida T1 - Clumping in Massive Star Winds and its Possible Connection to the B[e] Phenomenon T2 - The B(e) Phenomenon: Forty Years of Studies : proceedings of a conference held at Charles University, Prague, Czech Republic, 27 June-1 July 2016 N2 - It has been observationally established that winds of hot massive stars have highly variable characteristics. The variability evident in the winds is believed to be caused by structures on a broad range of spatial scales. Small-scale structures (clumping) in stellar winds of hot stars are possible consequence of an instability appearing in their radiation hydrodynamics. To understand how clumping may influence calculation of theoretical spectra, different clumping properties and their 3D nature have to be taken into account. Properties of clumping have been examined using our 3D radiative transfer calculations. Effects of clumping for the case of the B[e] phenomenon are discussed. Y1 - 2017 SN - 978-1-58381-900-5 SN - 978-1-58381-901-2 VL - 508 SP - 45 EP - 50 PB - Astronomical Soceity of the Pacific CY - San Fransisco ER - TY - GEN A1 - Kurfürst, P. A1 - Feldmeier, Achim A1 - Krtička, Jiri T1 - Modeling sgB[e] Circumstellar Disks T2 - The B(e) Phenomenon: Forty Years of Studies : proceedings of a conference held at Charles University, Prague, Czech Republic, 27 June-1 July 2016 N2 - During their evolution, massive stars are characterized by a significant loss of mass either via spherically symmetric stellar winds or by aspherical mass-loss mechanisms, namely outflowing equatorial disks. However, the scenario that leads to the formation of a disk or rings of gas and dust around these objects is still under debate. Is it a viscous disk or an ouftlowing disk-forming wind or some other mechanism? It is also unclear how various physical mechanisms that act on the circumstellar environment of the stars affect its shape, density, kinematic, and thermal structure. We assume that the disk-forming mechanism is a viscous transport within an equatorial outflowing disk of a rapidly or even critically rotating star. We study the hydrodynamic and thermal structure of optically thick dense parts of outflowing circumstellar disks that may form around,e.g., Be stars, sgB[e] stars, or Pop m stars. We calculate self-consistent time dependent models of the inner dense region of the disk that is strongly affected either by irradiation from the central star and by contributions of viscous heating effects. We also simulate the dynamic effects of collision between expanding ejecta of supernovae and circumstellar disks that may be form in sgB[e] stars and, e.g., LBVs or Pop in stars. Y1 - 2017 UR - https://www.physics.muni.cz/~petrk/presentation.pdf SN - 978-1-58381-900-5 SN - 978-1-58381-901-2 VL - 508 SP - 17 EP - 22 PB - Astronomical Scoeity of the Pacific CY - San Fransisco ER - TY - JOUR A1 - Bleyen, Pieter A1 - Klimovsky, Daniel A1 - Bouckaert, Geert A1 - Reichard, Christoph T1 - Linking budgeting to results? BT - Evidence about performance budgets in European municipalities based on a comparative analytical model JF - Public Management Review N2 - This article contributes to the debate on the incorporation of performance information in European local government budgets. At the core is the development of an analytical model for comparing efforts of performance budgeting (PB). Evidence in ten cases indicates that performance structures and the span of performance differ, that performance indicators are far from always measuring outcomes or outputs, and that future and past performance figures are often absent. Nevertheless similar learning trajectories do exist. Possible explanations for the variation involve the varying degrees of reform implementation, experience with PB and prevailing institutional arrangements. KW - Local government KW - performance budgeting KW - performance information Y1 - 2017 U6 - https://doi.org/10.1080/14719037.2016.1243837 SN - 1471-9037 SN - 1471-9045 VL - 19 IS - 7 SP - 932 EP - 953 PB - Routledge, Taylor & Francis Group CY - London ER - TY - JOUR A1 - Westbury, Michael V. A1 - Dalerumb, Fredrik A1 - Noren, Karin A1 - Hofreiter, Michael T1 - Complete mitochondrial genome of a bat-eared fox (Otocyon megalotis), along with phylogenetic considerations JF - Mitochondrial DNA. Part B N2 - The bat-eared fox, Otocyon megalotis, is the only member of its genus and is thought to occupy a basal position within the dog family. These factors can lead to challenges in complete mitochondrial reconstructions and accurate phylogenetic positioning. Here, we present the first complete mitochondrial genome of the bat-eared fox recovered using shotgun sequencing and iterative mapping to three distantly related species. Phylogenetic analyses placed the bat-eared fox basal in the Canidae family within the clade including true foxes (Vulpes) and the raccoon dog (Nyctereutes) with high support values. This position is in good agreement with previously published results based on short fragments of mitochondrial and nuclear genes, therefore adding more support to the basal positioning of the bat-eared fox within Canidae. KW - Phylogenetics KW - mitochondria KW - iterative mapping KW - Canidae Y1 - 2017 U6 - https://doi.org/10.1080/23802359.2017.1331325 SN - 2380-2359 VL - 2 IS - 1 SP - 298 EP - 299 PB - Routledge, Taylor & Francis Group CY - London ER - TY - JOUR A1 - Sändig, Brigitte T1 - Tragédie et psychologie BT - Camus devant le roman de Faulkner Requiem for a Nun JF - Revue romane : langue et littérature N2 - His dislike for psychological analysis accompanied Albert Camus throughout his life and had a profound impact on his idea of theatre. Especially in his early years, he sees psychology as the antagonist of the kind of theater that he envisages, the "modern tragedy". In the last decade of his life, Camus worked on the novel "Requiem for a Nun" by William Faulkner, whom he greatly respected, in order to stage it. The confrontation with this work and its highly psychologically driven plot makes Camus virtually give up on his anti-psychological attitude. KW - Theater KW - ancient tragedy KW - psychology KW - William Faulkner KW - Albert KW - Camus KW - Requiem for a Nun / Requiem pour une nonne Y1 - 2017 U6 - https://doi.org/10.1075/rro.52.1.07san SN - 0035-3906 SN - 1600-0811 VL - 52 IS - 1 SP - 70 EP - 79 PB - Benjamins CY - Amsterdam ER - TY - GEN A1 - Hocher, Berthold A1 - Yin, Lianghong T1 - Why Current PTH Assays Mislead Clinical Decision Making in Patients with Secondary Hyperparathyroidism T2 - Nephron N2 - Preclinical studies in cell culture systems as well as in whole animal chronic kidney disease (CKD) models showed that parathyroid hormone (PTH), oxidized at the 2 methionine residues (positions 8 and 18), caused a loss of function. This was so far not considered in the development of PTH assays used in current clinical practice. Patients with advanced CKD are subject to oxidative stress, and plasma proteins (including PTH) are targets for oxidants. In patients with CKD, a considerable but variable fraction (about 70 to 90%) of measured PTH appears to be oxidized. Oxidized PTH (oxPTH) does not interact with the PTH receptor resulting in loss of biological activity. Currently used intact PTH (iPTH) assays detect both oxidized and non-oxPTH (n-oxPTH). Clinical studies demonstrated that bioactive, n-oxPTH, but not iPTH nor oxPTH, is associated with mortality in CKD patients. KW - Serum intact-parathyroid hormone level KW - Dialysis patients KW - Mortality Y1 - 2017 U6 - https://doi.org/10.1159/000455289 SN - 1660-8151 SN - 2235-3186 SN - 0028-2766 VL - 136 IS - 2 SP - 137 EP - 142 PB - Karger CY - Basel ER - TY - GEN A1 - Alibabaie, Najmeh A1 - Ghasemzadeh, Mohammad A1 - Meinel, Christoph T1 - A variant of genetic algorithm for non-homogeneous population T2 - International Conference Applied Mathematics, Computational Science and Systems Engineering 2016 N2 - Selection of initial points, the number of clusters and finding proper clusters centers are still the main challenge in clustering processes. In this paper, we suggest genetic algorithm based method which searches several solution spaces simultaneously. The solution spaces are population groups consisting of elements with similar structure. Elements in a group have the same size, while elements in different groups are of different sizes. The proposed algorithm processes the population in groups of chromosomes with one gene, two genes to k genes. These genes hold corresponding information about the cluster centers. In the proposed method, the crossover and mutation operators can accept parents with different sizes; this can lead to versatility in population and information transfer among sub-populations. We implemented the proposed method and evaluated its performance against some random datasets and the Ruspini dataset as well. The experimental results show that the proposed method could effectively determine the appropriate number of clusters and recognize their centers. Overall this research implies that using heterogeneous population in the genetic algorithm can lead to better results. Y1 - 2017 U6 - https://doi.org/10.1051/itmconf/20170902001 SN - 2271-2097 VL - 9 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Schuster, Dirk T1 - European Culture and its Eastern Borders T1 - „Kulturelle Ostgrenzen“ Europas BT - Hans Heinrich Schaeder’s Thinking during the Third Reich BT - Hans Heinrich Schaeders Denken im „Dritten Reich“ JF - Osteuropa N2 - Hans Heinrich Schaeder is considered an important Iranist and historian of religion. For reasons of opportunism, careerism, and anti-Semitic resentment, he used the chance afforded him after the National Socialists seized power in Germany: he combined his historical and philological knowledge with National-Socialist racial ideology. Drawing on the superiority of “Aryanism” he derived from this merger, Schaeder tried to redefine the “Eastern Borders” of “European Culture”. In his concept, Armenians and Persians became integral elements of European culture and history, while Jews and “Semites” were excluded. In academia, publishing, and politics, he put himself at the service of the National-Socialist regime. In his own view, this served the struggle against Communism and the West’s social system. After the war, a de-Nazification commission concluded that there existed no reservations concerning his employment at Göttingen University. N2 - Hans Heinrich Schaeder gilt als bedeutender Iranist und Religionshistoriker. Nach der Machtergreifung der Nationalsozialisten in Deutschland nutzte er aus Opportunismus, Karrierismus und antisemitischem Ressentiment die neuen Chancen: Schaeder verband sein historisches und philologisches Wissen mit der nationalsozialistischen Rassenideologie. Aus der daraus abgeleiteten Überlegenheit des „Ariertums“ definierte er die kulturellen Ostgrenzen Europas neu. Armenier und Perser wurden nun zu integralen Bestandteilen der europäischen Kultur und Geschichte, während er Juden und „Semiten“ aus den Traditionsbeständen ausschloss. Akademisch, publizistisch und politisch stellte er sich in den Dienst des NS-Regimes. In seinem Selbstbild diente das dem Kampf gegen Kommunismus und das westliche Gesellschaftssystem. Nach dem Krieg kam eine Entnazifizierungskommission zu dem Ergebnis, dass gegen seine Beschäftigung an der Universität Göttingen keine Bedenken bestünden. Y1 - 2017 SN - 0030-6428 SN - 2509-3444 VL - 67 IS - 1-2 SP - 121 EP - 130 PB - Berliner Wissenschafts-Verlag CY - Berlin ER - TY - GEN A1 - Lorenz, Claas A1 - Kiekheben, Sebastian A1 - Schnor, Bettina T1 - FaVe: Modeling IPv6 firewalls for fast formal verification T2 - International Conference on Networked Systems (NetSys) 2017 N2 - As virtualization drives the automation of networking, the validation of security properties becomes more and more challenging eventually ruling out manual inspections. While formal verification in Software Defined Networks is provided by comprehensive tools with high speed reverification capabilities like NetPlumber for instance, the presence of middlebox functionality like firewalls is not considered. Also, they lack the ability to handle dynamic protocol elements like IPv6 extension header chains. In this work, we provide suitable modeling abstractions to enable both - the inclusion of firewalls and dynamic protocol elements. We exemplarily model the Linux ip6tables/netfilter packet filter and also provide abstractions for an application layer gateway. Finally, we present a prototype of our formal verification system FaVe. Y1 - 2017 U6 - https://doi.org/10.1109/NetSys.2017.7903956 PB - IEEE CY - New York ER - TY - GEN A1 - Gawron, Marian A1 - Cheng, Feng A1 - Meinel, Christoph T1 - PVD: Passive Vulnerability Detection T2 - 8th International Conference on Information and Communication Systems (ICICS) N2 - The identification of vulnerabilities relies on detailed information about the target infrastructure. The gathering of the necessary information is a crucial step that requires an intensive scanning or mature expertise and knowledge about the system even though the information was already available in a different context. In this paper we propose a new method to detect vulnerabilities that reuses the existing information and eliminates the necessity of a comprehensive scan of the target system. Since our approach is able to identify vulnerabilities without the additional effort of a scan, we are able to increase the overall performance of the detection. Because of the reuse and the removal of the active testing procedures, our approach could be classified as a passive vulnerability detection. We will explain the approach and illustrate the additional possibility to increase the security awareness of users. Therefore, we applied the approach on an experimental setup and extracted security relevant information from web logs. Y1 - 2017 SN - 978-1-5090-4243-2 U6 - https://doi.org/10.1109/IACS.2017.7921992 SN - 2471-125X SP - 322 EP - 327 PB - IEEE CY - New York ER - TY - GEN A1 - Mühlbauer, Felix A1 - Schröder, Lukas A1 - Skoncej, Patryk A1 - Schölzel, Mario T1 - Handling manufacturing and aging faults with software-based techniques in tiny embedded systems T2 - 18th IEEE Latin American Test Symposium (LATS 2017) N2 - Non-volatile memory area occupies a large portion of the area of a chip in an embedded system. Such memories are prone to manufacturing faults, retention faults, and aging faults. The paper presents a single software based technique that allows for handling all of these fault types in tiny embedded systems without the need for hardware support. This is beneficial for low-cost embedded systems with simple memory architectures. A software infrastructure and a flow are presented that demonstrate how the presented technique is used in general for fault handling right after manufacturing and in-the-field. Moreover, a full implementation is presented for a MSP430 microcontroller, along with a discussion of the performance, overhead, and reliability impacts. Y1 - 2027 SN - 978-1-5386-0415-1 U6 - https://doi.org/10.1109/LATW.2017.7906756 PB - IEEE CY - New York ER - TY - GEN A1 - Mühlbauer, Felix A1 - Schröder, Lukas A1 - Schölzel, Mario T1 - On hardware-based fault-handling in dynamically scheduled processors T2 - 20th International Symposium on Design and Diagnostics of Electronic Circuits & Systems (DDECS) 2017 N2 - This paper describes architectural extensions for a dynamically scheduled processor, so that it can be used in three different operation modes, ranging from high-performance, to high-reliability. With minor hardware-extensions of the control path, the resources of the superscalar data-path can be used either for high-performance execution, fail-safe-operation, or fault-tolerant-operation. This makes the processor-architecture a very good candidate for applications with dynamically changing reliability requirements, e.g. for automotive applications. The paper reports the hardware-overhead for the extensions, and investigates the performance penalties introduced by the fail-safe and fault-tolerant mode. Furthermore, a comprehensive fault simulation was carried out in order to investigate the fault-coverage of the proposed approach. Y1 - 2017 SN - 978-1-5386-0472-4 U6 - https://doi.org/10.1109/DDECS.2017.7934572 SN - 2334-3133 SN - 2473-2117 SP - 201 EP - 206 PB - IEEE CY - New York ER - TY - GEN A1 - Malchow, Martin A1 - Renz, Jan A1 - Bauer, Matthias A1 - Meinel, Christoph T1 - Embedded smart home BT - remote lab grading in a MOOC with over 6000 participants T2 - 11th Annual IEEE International Systems Conference (SysCon) N2 - The popularity of MOOCs has increased considerably in the last years. A typical MOOC course consists of video content, self tests after a video and homework, which is normally in multiple choice format. After solving this homeworks for every week of a MOOC, the final exam certificate can be issued when the student has reached a sufficient score. There are also some attempts to include practical tasks, such as programming, in MOOCs for grading. Nevertheless, until now there is no known possibility to teach embedded system programming in a MOOC course where the programming can be done in a remote lab and where grading of the tasks is additionally possible. This embedded programming includes communication over GPIO pins to control LEDs and measure sensor values. We started a MOOC course called "Embedded Smart Home" as a pilot to prove the concept to teach real hardware programming in a MOOC environment under real life MOOC conditions with over 6000 students. Furthermore, also students with real hardware have the possibility to program on their own real hardware and grade their results in the MOOC course. Finally, we evaluate our approach and analyze the student acceptance of this approach to offer a course on embedded programming. We also analyze the hardware usage and working time of students solving tasks to find out if real hardware programming is an advantage and motivating achievement to support students learning success. Y1 - 2017 SN - 978-1-5090-4623-2 U6 - https://doi.org/10.1109/SYSCON.2017.7934728 SN - 1944-7620 SP - 195 EP - 200 PB - IEEE CY - New York ER - TY - GEN A1 - Angerer, Marie-Luise T1 - Moving Forces T2 - The minnesota review N2 - Throughout a large part of the twentieth century, the body was interpreted as a field of signs, the meaning of which pointed to an unconscious dimension. At the height of the popularity of structuralism, Jacques Lacan deemed the unconscious to be “structured like a language.” Starting in the early 1990s, however, a deep shift occurred in the way the body was interpreted. A new movement cast tremendous doubt on the hegemony of language and instead advocated a performative, pictorial, and affective approach — the so-called material turn — which encompassed all of these. In the words of Karen Barad, this turn inquired as to why meaning, history, and truth are assigned to language only, whereas the movements of materiality are given less prominence: “How did language come to be more trustworthy than matter? Why are language and culture granted their own agency and historicity while matter is figured as passive and immutable?” With this shift toward the material, bodies began to be seen in a different light and their materiality understood as something that follows its own laws and movements, which cannot be understood exclusively in terms of social-cultural codes. Instead, these laws and movements call into question the very dichotomies of nature/culture and body/spirit. KW - mattering KW - wondering KW - contingent encounters KW - affect KW - blind feeling KW - sensation Y1 - 2017 U6 - https://doi.org/10.1215/00265667-3787414 SN - 0026-5667 SN - 2157-4189 VL - 88 SP - 83 EP - 95 PB - Duke Univ. Press CY - Durham ER - TY - GEN A1 - Neubauer, Kai A1 - Wanko, Philipp A1 - Schaub, Torsten H. A1 - Haubelt, Christian T1 - Enhancing symbolic system synthesis through ASPmT with partial assignment evaluation T2 - Proceedings of the Design, Automation & Test in Europe Conference & Exhibition (DATE), 2017 N2 - The design of embedded systems is becoming continuously more complex such that efficient system-level design methods are becoming crucial. Recently, combined Answer Set Programming (ASP) and Quantifier Free Integer Difference Logic (QF-IDL) solving has been shown to be a promising approach in system synthesis. However, this approach still has several restrictions limiting its applicability. In the paper at hand, we propose a novel ASP modulo Theories (ASPmT) system synthesis approach, which (i) supports more sophisticated system models, (ii) tightly integrates the QF-IDL solving into the ASP solving, and (iii) makes use of partial assignment checking. As a result, more realistic systems are considered and an early exclusion of infeasible solutions improves the entire system synthesis. Y1 - 2017 SN - 978-3-9815370-9-3 U6 - https://doi.org/10.23919/DATE.2017.7927005 SN - 1530-1591 SP - 306 EP - 309 PB - IEEE CY - New York ER - TY - GEN A1 - Staubitz, Thomas A1 - Wilkins, Christian A1 - Hagedorn, Christiane A1 - Meinel, Christoph T1 - The Gamification of a MOOC Platform T2 - Proceedings of 2017 IEEE Global Engineering Education Conference (EDUCON) N2 - Massive Open Online Courses (MOOCs) have left their mark on the face of education during the recent years. At the Hasso Plattner Institute (HPI) in Potsdam, Germany, we are actively developing a MOOC platform, which provides our research with a plethora of e-learning topics, such as learning analytics, automated assessment, peer assessment, team-work, online proctoring, and gamification. We run several instances of this platform. On openHPI, we provide our own courses from within the HPI context. Further instances are openSAP, openWHO, and mooc.HOUSE, which is the smallest of these platforms, targeting customers with a less extensive course portfolio. In 2013, we started to work on the gamification of our platform. By now, we have implemented about two thirds of the features that we initially have evaluated as useful for our purposes. About a year ago we activated the implemented gamification features on mooc.HOUSE. Before activating the features on openHPI as well, we examined, and re-evaluated our initial considerations based on the data we collected so far and the changes in other contexts of our platforms. KW - MOOC KW - Gamification KW - e-learning KW - Massive Open Online Courses Y1 - 2017 SN - 978-1-5090-5467-1 U6 - https://doi.org/10.1109/EDUCON.2017.7942952 SN - 2165-9567 SP - 883 EP - 892 PB - IEEE CY - New York ER - TY - JOUR A1 - Haag, Johannes T1 - A kantian critique of sellars transcendental realism JF - Wilfrid Sellars, Idealism, and Realism: Understanding Psychological Nominalism Y1 - 2017 SN - 978-1-4742-3895-3 SN - 978-1-4742-3893-9 SN - 978-1-4742-3894-6 SP - 149 EP - 171 PB - Bloomsbury CY - London ER - TY - JOUR A1 - Meer, Frans-Bauke van der A1 - Reichard, Christoph A1 - Ringeling, Arthur T1 - Becoming a Student of Reform JF - Theory and practice of public sector reform Y1 - 2016 SN - 978-1-315-71414-1 SN - 978-1-317-50011-7 SN - 978-1-317-50012-4 VL - 27 SP - 265 EP - 283 PB - Routledge CY - New York ER - TY - CHAP A1 - Schmidt, Marco F. ED - Schmidt, Marco F. T1 - Preface T2 - Drug target miRNA Y1 - 2016 SN - 978-1-4939-6563-2 SN - 978-1-4939-6561-8 U6 - https://doi.org/10.1007/978-1-4939-6563-2 SN - 1064-3745 SN - 1940-6029 VL - 1517 SP - V EP - V PB - Springer CY - New York ER - TY - BOOK ED - Schmidt, Marco F. T1 - Drug target miRNA BT - methods and protocols T3 - Methods in Molecular Biology N2 - This volume provides a concise and technical discussion of recently developed approaches to overcome challenges in miRNA drug discovery. Drug Target miRNA: Methods and Protocols explores strategies to overcome pharmacodynamics and pharmacokinetics challenges. These strategies cover anti-sense agents targeting miRNA that are applied in advanced formulations or are chemically optimized to increase delivery; small molecule miRNA modulators to overcome anti-sense agents’ limitations; general enhancers of miRNA maturation; and Argonaute 2 protein and its pharmacokinetic parameters. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Drug Target miRNA: Methods and Protocols is a valuable resource for anyone interested in the ever-evolving field of miRNA drug discovery. Y1 - 2017 SN - 978-1-4939-6561-8 SN - 978-1-4939-6563-2 U6 - https://doi.org/10.1007/978-1-4939-6563-2 SN - 1064-3745 SN - 1940-6029 PB - Springer CY - New York ER - TY - CHAP A1 - Grum, Marcus A1 - Bender, Benedict A1 - Alfa, Attahiru S. T1 - The construction of a common objective function for analytical infrastructures T2 - 2017 International Conference on Engineering, Technology and Innovation (ICE/ITMC) N2 - The paper deals with the increasing growth of embedded systems and their role within structures similar to the Internet (Internet of Things) as those that provide calculating power and are more or less appropriate for analytical tasks. Faced with the example of a cyber-physical manufacturing system, a common objective function is developed with the intention to measure efficient task processing within analytical infrastructures. A first validation is realized on base of an expert panel. KW - Analytic Infrastructures KW - Cyber-Physical Manufacturing Systems KW - Measuring Efficient Task Processing Y1 - 2018 U6 - https://doi.org/10.1109/ICE.2017.8279892 SP - 219 EP - 225 PB - IEEE CY - New York ER - TY - CHAP A1 - Schlosser, Rainer A1 - Boissier, Martin ED - Liberatore, Federico ED - Parlier, Greg H. ED - Demange, Marc T1 - Optimal price reaction strategies in the presence of active and passive competitors T2 - Proceedings of the 6th International Conference on Operations Research and Enterprise Systems - ICORES N2 - Many markets are characterized by pricing competition. Typically, competitors are involved that adjust their prices in response to other competitors with different frequencies. We analyze stochastic dynamic pricing models under competition for the sale of durable goods. Given a competitor’s pricing strategy, we show how to derive optimal response strategies that take the anticipated competitor’s price adjustments into account. We study resulting price cycles and the associated expected long-term profits. We show that reaction frequencies have a major impact on a strategy’s performance. In order not to act predictable our model also allows to include randomized reaction times. Additionally, we study to which extent optimal response strategies of active competitors are affected by additional passive competitors that use constant prices. It turns out that optimized feedback strategies effectively avoid a decline in price. They help to gain profits, especially, when aggressive competitor s are involved. KW - Dynamic Pricing KW - Competition KW - Optimal Control KW - Response Strategies KW - Reaction Time KW - Price Cycles Y1 - 2017 SN - 978-989-758-218-9 U6 - https://doi.org/10.5220/0006118200470056 SP - 47 EP - 56 PB - SCITEPRESS - Science and Technology Publications, Lda. CY - Setúbal ER - TY - CHAP A1 - Bender, Benedict A1 - Gronau, Norbert T1 - Coring on Digital Platforms BT - Fundamentals and Examples from the Mobile Device Sector T2 - Proceedings of the 38th International Conference on Information Systems (ICIS) N2 - Today’s mobile devices are part of powerful business ecosystems, which usually involve digital platforms. To better understand the complex phenomenon of coring and related dynamics, this paper presents a case study comparing iMessage as part of Apple’s iOS and WhatsApp. Specifically, it investigates activities regarding platform coring, as the integration of several functionalities provided by third-party applications in the platform core. The paper makes three contributions. First, a systematization of coring activities is developed. Coring modes are differentiated by the amount of coring and application maintenance. Second, the case study revealed that the phenomenon of platform coring is present on digital platforms for mobile devices. Third, the fundamentals of coring are discussed as a first step towards theoretical development. Even though coring constitutes a potential threat for third-party developers regarding their functional differentiation, an idea of what a beneficial partnership incorporating coring activities could look like is developed here. KW - Coring KW - Digital Platforms KW - Digital Marketplaces KW - Mobile Software Ecosystems Y1 - 2017 UR - https://aisel.aisnet.org/icis2017/DigitalPlatforms/Presentations/6/ SN - 978-0-9966831-5-9 IS - 8 SP - 5256 EP - 5274 PB - Association for Information Systems (AIS) CY - Atlanta ER - TY - JOUR A1 - Bareither, Nils A1 - Scheffel, Andre A1 - Metz, Johannes T1 - Distribution of polyploid plants in the common annual Brachypodium distachyon (s.l.) in Israel is not linearly correlated with aridity JF - Israel Journal of Plant Sciences N2 - The ecological benefits of polyploidy are intensely debated. Some authors argue that plants with duplicated chromosome sets (polyploids) are more stress- resistant and superior colonizers and may thus outnumber their low ploidy conspecifics in more extreme habitats. Brachypodium distachyon (sensu lato), for example, a common annual grass in Israel and the entire Mediterranean basin, comprises three cytotypes of differing chromosome numbers that were recently proposed as distinct species. It was suggested that increased aridity increases the occurrence of its polyploid cytotype. Here, we tested at two spatial scales whether polyploid plants of B. distachyon s. l. are more frequently found in drier habitats in Israel. We collected a total of 430 specimens (i) along a largescale climatic gradient with 15 thoroughly selected sites (spanning 114- 954 mm annual rainfall), and (ii) from corresponding Northern (more mesic) and Southern (more arid) hill slopes to assess the micro- climatic difference between contrasting exposures. Cytotypes were then determined via flow cytometry. Polyploid plants comprised 90% of all specimens and their proportion ranged between 0% and 100% per site. However, this proportion was not correlated with aridity along the large- scale gradient, nor were polyploids more frequently found on Southern exposures. Our results show for both spatial scales that increasing aridity is not the principal driver for the distribution of polyploids in B. distachyon s. l. in Israel. Notably, though, diploid plants were restricted essentially to four intermediate sites, while polyploids dominated the most arid and the most mesic sites. This, to some degree, clustered pattern suggests that the distribution of cytotypes is not entirely random and calls for future studies to assess further potential drivers. KW - Aridity KW - Brachypodium distachyon KW - Brachypodium hybridum KW - Brachypodium stacei KW - cytotype KW - exposition KW - Israel KW - Mediterranean grass species KW - polyploidization KW - rainfall gradient KW - slope aspect Y1 - 2017 SN - 0792-9978 SN - 2223-8980 VL - 64 SP - 83 EP - 92 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Dereudre, David A1 - Mazzonetto, Sara A1 - Roelly, Sylvie T1 - Exact simulation of Brownian diffusions with drift admitting jumps JF - SIAM journal on scientific computing N2 - In this paper, using an algorithm based on the retrospective rejection sampling scheme introduced in [A. Beskos, O. Papaspiliopoulos, and G. O. Roberts,Methodol. Comput. Appl. Probab., 10 (2008), pp. 85-104] and [P. Etore and M. Martinez, ESAIM Probab.Stat., 18 (2014), pp. 686-702], we propose an exact simulation of a Brownian di ff usion whose drift admits several jumps. We treat explicitly and extensively the case of two jumps, providing numerical simulations. Our main contribution is to manage the technical di ffi culty due to the presence of t w o jumps thanks to a new explicit expression of the transition density of the skew Brownian motion with two semipermeable barriers and a constant drift. KW - exact simulation methods KW - skew Brownian motion KW - skew diffusions KW - Brownian motion with discontinuous drift Y1 - 2017 U6 - https://doi.org/10.1137/16M107699X SN - 1064-8275 SN - 1095-7197 VL - 39 IS - 3 SP - A711 EP - A740 PB - Society for Industrial and Applied Mathematics CY - Philadelphia ER - TY - CHAP A1 - Bookhagen, Bodo ED - Prins, Herbert H.T. ED - Namgail, Tsewang T1 - The influence of hydrology and glaciology on wetlands in the Himalayas T2 - Bird migration across the Himalayas : wetland functioning amidst mountains and glaciers N2 - Birds migrating across the Himalayan region fly over the highest peaks in the world, facing immense physiological and climatic challenges. The authors show the different strategies used by birds to cope with these challenges. Many wetland avian species are seen in the high-altitude lakes of the Himalayas and the adjoining Tibetan Plateau, such as Bar-Headed Geese. Ringing programmes have generated information about origins and destinations, and this book is the first to present information on the bird's exact migratory paths. Capitalising on knowledge generated through satellite telemetry, the authors describe the migratory routes of a multitude of birds flying over or skirting the Himalayas. The myriad of threats to migratory birds and the wetland system in the Central Asian Flyway are discussed, with ways to mitigate them. This volume will inform and persuade policy-makers and conservation practitioners to take appropriate measures for the long-term survival of this unique migration Y1 - 2017 SN - 978-1-107-11471-5 SN - 978-1-316-33542-0 U6 - https://doi.org/10.1017/9781316335420 SP - 175 EP - 188 PB - Cambridge University Press CY - Cambridge ER - TY - JOUR A1 - García-Camacho, Raúl A1 - Metz, Johannes A1 - Bilton, Mark C. A1 - Tielboerger, Katja T1 - Phylogenetic structure of annual plant communities along an aridity gradient BT - Interacting effects of habitat filtering and shifting plant-plant interactions JF - Israel Journal of Plant Sciences N2 - The phylogenetic structure of communities (PSC) reveals how evolutionary history affects community assembly processes. However, there are important knowledge gaps on PSC patterns for annual communities and there is a need for studies along environmental gradients in dry ecosystems where several processes shape PSC. Here, we investigated the PSC of annual plants along an aridity gradient in Israel, including eight years, two spatial scales, the effects of shrubs on understory, and the phylogenetic signal of important traits. Increasing drought stress led to overdispersed PSC at the drier end of the gradient, indicating that species were less related than expected by chance. This was supported at a smaller spatial scale, where within the drier sites, communities in open- more arid- habitats were more overdispersed than those under nurse shrubs. Interestingly, some key traits related to drought resistance were not conserved in the phylogeny. Together, our findings suggested that while habitat filtering selected for drought resistance strategies, these strategies evolved independently along multiple contrasting evolutionary lineages. Our comprehensive PSC study provides strong evidence for the interacting effects of habitat filtering and plant- plant interactions, particularly highlighting that the conservative evolution of traits should not be assumed in future interpretations of PSC patterns. KW - Annuals KW - aridity gradient KW - community assembly rules KW - community phylogenetics KW - stress-gradient hypothesis KW - trait phylogenetic conservatism Y1 - 2017 U6 - https://doi.org/10.1080/07929978.2017.1288477 SN - 0792-9978 SN - 2223-8980 VL - 64 IS - 1-2 SP - 122 EP - 134 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Brechenmacher, Thomas A1 - Delgado, Mariano T1 - Re-formation - zu einem Strukturprinzip der Christentums- und Religionsgeschichte BT - Kurzer Sektionsüberblick JF - Historisches Jahrbuch Y1 - 2017 SN - 978-3-495-45294-3 SN - 0018-2621 VL - 137 SP - 3 EP - 6 PB - Alber CY - Freiburg, Breisgau ER - TY - JOUR A1 - Ehrensperger, Kathy T1 - Trajectories and future avenues in Pauline Studies and Jewish–Christian relations BT - the relevance of William S. Campbell’s approach to Paul JF - Journal of beliefs and values : studies in religion & education N2 - William S. Campbell’s research on the apostle Paul has been at the forefront of overcoming anti-Jewish interpretations. His career has been characterised by academic rigour and social and interfaith engagement. His interpretive approach is committed to formulating Christian identity in positive relation to others and thus contributes to provide a vital basis for Jewish-Christian and Interfaith relations in general for the future. KW - Pauline studies KW - Christian identity KW - diversity KW - anti-judaism KW - Jewish-Christian relations KW - interfaith relations Y1 - 2017 U6 - https://doi.org/10.1080/13617672.2017.1314988 SN - 1361-7672 SN - 1469-9362 VL - 38 IS - 2 SP - 153 EP - 158 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Herbst, Uta A1 - Kemmerling, Birte Christina A1 - Neale, Margaret A. T1 - All in, one-at-a-time or somewhere in the middle? BT - Leveraging the composition and size of the negotiating package JF - The journal of business & industrial marketing N2 - Purpose: While industrial marketers have long bundled their products and services to sell them as packages, to what extent should negotiators also rely on packaging their offers? Clearly, negotiating at a package level can tax the cognitive capacity of the involved parties at some point. Therefore, this study aims to analyze the impact of the number and type of issues that should be negotiated simultaneously to leverage the package strategy efficiently and effectively in multi-issue buyer-seller negotiations. Design/methodology/approach: The authors conducted and analyzed negotiation simulations with 676 students from 2 public universities. Findings: The authors’ results suggest that negotiating three out of six issues simultaneously is the least efficient but most effective strategy in multi-issue buyer-seller negotiations. Moreover, they found that bundling distributive and integrative issues is more efficient and effective than only bundling distributive or integrative negotiation issues in a package offer. Originality/value: Past research has examined the impact of negotiating a package as compared to each issue separately; however, little empirical attention has been directed toward understanding how to apply a package strategy in complex multi-issue negotiations. KW - Negotiation performance KW - Issue bundling KW - Joint negotiation outcome KW - Number of offers KW - Package strategy Y1 - 2017 U6 - https://doi.org/10.1108/JBIM-12-2015-0251 SN - 0885-8624 SN - 2052-1189 VL - 32 IS - 4 SP - 580 EP - 586 PB - Emerald Group Publishing Limited CY - Bingley ER - TY - JOUR A1 - Homolka, Walter T1 - Truthfulness and the permissibility of falsehood in the Jewish tradition JF - Journal of beliefs and values : studies in religion & education N2 - In this article, I deal with the concept of truth and lie in Jewish traditional literature, examining its development in the Hebrew Bible and rabbinic literature. An essential aspect in understanding this concept is the dualism of ‘good’ and ‘evil’ impulses and the free will of human beings, who were created in the image of God and have the choice to decide between right and wrong. KW - sin KW - Truthfulness KW - falsehood KW - Jewish tradition KW - lie KW - free will KW - God’s image Y1 - 2017 U6 - https://doi.org/10.1080/13617672.2017.1291253 SN - 1361-7672 SN - 1469-9362 VL - 38 IS - 2 SP - 180 EP - 187 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Acevedo, Walter A1 - De Wiljes, Jana A1 - Reich, Sebastian T1 - Second-order accurate ensemble transform particle filters JF - SIAM journal on scientific computing N2 - Particle filters (also called sequential Monte Carlo methods) are widely used for state and parameter estimation problems in the context of nonlinear evolution equations. The recently proposed ensemble transform particle filter (ETPF) [S. Reich, SIAM T. Sci. Comput., 35, (2013), pp. A2013-A2014[ replaces the resampling step of a standard particle filter by a linear transformation which allows for a hybridization of particle filters with ensemble Kalman filters and renders the resulting hybrid filters applicable to spatially extended systems. However, the linear transformation step is computationally expensive and leads to an underestimation of the ensemble spread for small and moderate ensemble sizes. Here we address both of these shortcomings by developing second order accurate extensions of the ETPF. These extensions allow one in particular to replace the exact solution of a linear transport problem by its Sinkhorn approximation. It is also demonstrated that the nonlinear ensemble transform filter arises as a special case of our general framework. We illustrate the performance of the second-order accurate filters for the chaotic Lorenz-63 and Lorenz-96 models and a dynamic scene-viewing model. The numerical results for the Lorenz-63 and Lorenz-96 models demonstrate that significant accuracy improvements can be achieved in comparison to a standard ensemble Kalman filter and the ETPF for small to moderate ensemble sizes. The numerical results for the scene-viewing model reveal, on the other hand, that second-order corrections can lead to statistically inconsistent samples from the posterior parameter distribution. KW - Bayesian inference KW - data assimilation KW - particle filter KW - ensemble Kalman filter KW - Sinkhorn approximation Y1 - 2017 U6 - https://doi.org/10.1137/16M1095184 SN - 1064-8275 SN - 1095-7197 SN - 2168-3417 VL - 39 IS - 5 SP - A1834 EP - A1850 PB - Society for Industrial and Applied Mathematics CY - Philadelphia ER - TY - JOUR A1 - Schorsch, Jonathan T1 - Modern Angels, Avant-Gardes and the Esoteric Archive JF - Lux in Tenebris : The Visual and the Symbolic in Western Esotericism Y1 - 2016 SN - 978-90-04-33495-3 SN - 978-90-04-33494-6 U6 - https://doi.org/10.1163/9789004334953_018 SN - 1871-1405 VL - 23 SP - 397 EP - 424 PB - Brill CY - Leiden ER - TY - JOUR A1 - Kunow, Rüdiger T1 - The biology of geography disease disease and disease ecologies in the Americas JF - The Routledge companion to inter-American studies Y1 - 2017 SN - 978-1-315-64498-1 SN - 978-1-138-18467-1 SP - 296 EP - 307 PB - Routledge CY - Abingdon ER - TY - JOUR A1 - Ludwig, Joachim T1 - A subject-theoretical perspective on transformative learning and transformative Bildung BT - Transformative Bildung as a Research Strategy on the Processes of Bildung JF - Transformative learning meets Bildung : an international exchange N2 - The German theory on transformative Bildung (Koller, Marotzki, & Sanders, 2007; Koller, 2012; Nohl, 2014) deals with transformation processes in human thinking. Bildung is defined as self and world reference, causing change in the fundamental orientation of people in the course of their biography. Y1 - 2017 SN - 978-94-6300-795-5 SN - 978-94-6300-796-2 SN - 978-94-6300-797-9 U6 - https://doi.org/10.1007/978-94-6300-797-9_4 VL - 21 SP - 43 EP - 55 PB - Sense Publishers CY - Rotterdam ER - TY - JOUR A1 - Lange, Jerome A1 - Schumacher, Reinhard A1 - Svorencik, Andrej T1 - From antiquity to modern macro BT - an overview of contemporary scholarship in the history of economic thought journals, 2015-2016 JF - History of economic ideas N2 - This survey provides an overview of topics related to the history of economics that have been discussed within the last two years in journal articles. The survey format has been started by History of Economic Ideas last year with the survey by Giulia Bianchi (2016) and is aimed to increase the visibility of research in the history of economics. The emphasis of our survey is on the big three journals in the history of economics: the European Journal of the History of Economic Thought, the Journal of the History of Economic Thought and History of Political Economy. We also included additional journals that frequently publish articles related to the history of economics. These include, in alphabetical order, the Cambridge Journal of Economics, Contributions to Political Economy, Economic Thought, the Erasmus Journal for Philosophy and Economics, History of Economic Thought and Policy, the History of Economics Review, the Journal of Economic Literature, the Journal of Economic Methodology, the Journal of Economic Perspectives, OE conomia, Oxford Economic Papers and Research in the History of Economic Thought and Methodology. KW - History of economics KW - survey of literature KW - preclassical economics KW - classical economics KW - 20th-century economics Y1 - 2017 UR - http://digital.casalini.it/10.19272/201706102007 U6 - https://doi.org/10.19272/201706102007 SN - 1122-8792 SN - 1724-2169 VL - 25 IS - 2 SP - 171 EP - 205 PB - Fabrizio Serra Editore CY - Pisa ER - TY - GEN A1 - Thoelert, Steffen A1 - Hörmann, Ulrich A1 - Antreich, Felix A1 - Meurer, Michael T1 - Ionospheric effects on high gain antenna GNSS measurements BT - TEC estimation and correction T2 - Proceedings of the 30th International Technical Meeting of the Satellite Division of The Institute of Navigation (ION GNSS+ 2017) N2 - The ionospheric delay of global navigation satellite systems (GNSS) signals typically is compensated by adding a single correction value to the pseudorange measurement of a GNSS receiver. Yet, this neglects the dispersive nature of the ionosphere. In this context we analyze the ionospheric signal distortion beyond a constant delay. These effects become increasingly significant with the signal bandwidth and hence more important for new broadband navigation signals. Using measurements of the Galileo E5 signal, captured with a high gain antenna, we verify that the expected influence can indeed be observed and compensated. A new method to estimate the total electron content (TEC) from a single frequency high gain antenna measurement of a broadband GNSS signal is proposed and described in detail. The received signal is de facto unaffected by multi-path and interference because of the narrow aperture angle of the used antenna which should reduce the error source of the result in general. We would like to point out that such measurements are independent of code correlation, like in standard receiver applications. It is therefore also usable without knowledge of the signal coding. Results of the TEC estimation process are shown and discussed comparing to common TEC products like TEC maps and dual frequency receiver estimates. Y1 - 2017 U6 - https://doi.org/10.33012/2017.15343 SN - 2331-5911 SN - 2331-5954 SP - 3368 EP - 3374 PB - Instituite of Navigation CY - Washington ER - TY - JOUR A1 - Wyrwa, Ulrich T1 - Zum Hundertsten nichts Neues T1 - For the Hundredth nothing BT - Deutschsprachige Neuerscheinungen zum Ersten Weltkrieg (Teil III) BT - New German Language New Releases to the First World War (Part III) JF - Deutsche Zeitschrift für Geschichtswissenschaft Y1 - 2017 SN - 0044-2828 VL - 65 IS - 11 SP - 955 EP - 976 PB - Metropol-Verl. CY - Berlin ER - TY - GEN A1 - Laubrock, Jochen A1 - Engbert, Ralf A1 - Cajar, Anke T1 - Gaze-contingent manipulation of the FVF demonstrates the importance of fixation duration for explaining search behavior T2 - Behavioral and brain sciences : an international journal of current research and theory with open peer commentary N2 - Hulleman & Olivers' (H&O's) model introduces variation of the functional visual field (FVF) for explaining visual search behavior. Our research shows how the FVF can be studied using gaze-contingent displays and how FVF variation can be implemented in models of gaze control. Contrary to H&O, we believe that fixation duration is an important factor when modeling visual search behavior. Y1 - 2017 U6 - https://doi.org/10.1017/S0140525X16000145 SN - 0140-525X SN - 1469-1825 VL - 40 SP - 31 EP - 32 PB - Cambridge Univ. Press CY - New York ER - TY - JOUR A1 - Hörmann, Simon A1 - dos Santos, Luara Ferreira A1 - Morkisch, Nadine A1 - Jettkowski, Katrin A1 - Sillis, Moran A1 - Devan, Hemakumar A1 - Kanagasabai, Parimala S. A1 - Schmidt, Henning A1 - Krüger, Jörg A1 - Dohle, Christian A1 - Regenbrecht, Holger A1 - Hale, Leigh A1 - Cutfield, Nicholas J. T1 - Computerised mirror therapy with Augmented Reflection Technology for early stroke rehabilitation BT - clinical feasibility and integration as an adjunct therapy JF - Disability and rehabilitation : an international, multidisciplinary journal N2 - Purpose: New rehabilitation strategies for post-stroke upper limb rehabilitation employing visual stimulation show promising results, however, cost-efficient and clinically feasible ways to provide these interventions are still lacking. An integral step is to translate recent technological advances, such as in virtual and augmented reality, into therapeutic practice to improve outcomes for patients. This requires research on the adaptation of the technology for clinical use as well as on the appropriate guidelines and protocols for sustainable integration into therapeutic routines. Here, we present and evaluate a novel and affordable augmented reality system (Augmented Reflection Technology, ART) in combination with a validated mirror therapy protocol for upper limb rehabilitation after stroke. Results: The results showed that the combination and application of the Berlin Protocol for Mirror Therapy together with ART was feasible for clinical use. This combination was integrated into the therapeutic plan of subacute stroke patients at the two clinical locations where the second part of this research was conducted. Conclusions: Our findings pave the way for using technology to provide mirror therapy in clinical settings and show potential for the more effective use of inpatient time and enhanced recoveries for patients. IMPLICATIONS FOR REHABILITATION Computerised Mirror Therapy is feasible for clinical use Augmented Reflection Technology can be integrated as an adjunctive therapeutic intervention for subacute stroke patients in an inpatient setting Virtual Rehabilitation devices such as Augmented Reflection Technology have considerable potential to enhance stroke rehabilitation KW - Augmented reality KW - virtual reality KW - usability KW - user experience KW - upper limb KW - visual illusion Y1 - 2017 U6 - https://doi.org/10.1080/09638288.2017.1291765 SN - 0963-8288 SN - 1464-5165 VL - 39 SP - 1503 EP - 1514 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Falk, Thomas A1 - Kirk, Michael A1 - Lohmann, Dirk A1 - Kruger, Bertus A1 - Hüttich, Christian A1 - Kamukuenjandje, Richard T1 - The profits of excludability and transferability in redistributive land reform in central Namibia JF - Development Southern Africa N2 - Policies which redistribute property rights to land can improve the well-being of rural households and can have overall growth effects. In many cases, however, land reforms are driven mainly by politically justified objectives. Under such circumstances, little emphasis is placed on whether and, if so, how property rights can increase productivity. Following 18 years of land reform implementation in Namibia, we evaluated 65 beneficiaries in Namibia. We assess to which degree land rights affects their farm income. The study focuses on Namibia’s two main commercial land reform instruments, namely the Farm Unit Resettlement Scheme and the Affirmative Action Loan Scheme. We find evidence that the majority of land reform projects are not profitable. Further, our study confirms the importance of the right to restrict land access compared with the right to transfer. The long-term leasehold contract seemingly provides sufficient incentives to make productive use of the land. KW - Redistributive land reform KW - property rights KW - farm productivity KW - pastoralism KW - Namibia Y1 - 2017 U6 - https://doi.org/10.1080/0376835X.2016.1269633 SN - 0376-835X SN - 1470-3637 VL - 34 SP - 314 EP - 329 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - McElvenny, James T1 - Grammar, typology and the Humboldtian tradition in the work of Georg von der Gabelentz JF - Language & history : journal of the Henry Sweet Society for the History of Linguistic Ideas N2 - A frequently mentioned if somewhat peripheral figure in the historiography of late nineteenth-century linguistics is the German sinologist and general linguist Georg von der Gabelentz (1840–1893). Today Gabelentz is chiefly remembered for several insights that proved to be productive in the development of subsequent schools and subdisciplines. In this paper, we examine two of these insights, his analytic and synthetic systems of grammar and his foundational work on typology. We show how they were intimately connected within his conception of linguistic research, and how this was in turn embedded in the tradition established by Wilhelm von Humboldt (1767–1835), especially as it was further developed by H. Steinthal (1823–1899). This paper goes beyond several previous works with a similar focus by drawing on a wider range of Gabelentz’ writings, including manuscript sources that have only recently been published, and by examining specific textual connections between Gabelentz and his predecessors. KW - History of linguistics KW - typology KW - language description KW - grammar KW - Humboldtian linguistics KW - Georg von der Gabelentz KW - H . Steinthal KW - Wilhelm von Humboldt Y1 - 2017 U6 - https://doi.org/10.1080/17597536.2016.1212580 SN - 1759-7536 SN - 1759-7544 VL - 60 SP - 1 EP - 20 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Prieto, Julio T1 - From blind shorthand T1 - de la ciega taquigrafía BT - the elusive erudition of Luis Chitarroni BT - la elusiva erudición de Luis Chitarroni JF - Cahiers de LIRICO N2 - This essay explores the poetics of obscurity that informs Luis Chitarroni’s « unfinished novel » The No Variations. Focusing on the « reticent » erudition that distinguishes this text, my analysis examines its dialogue with the paradigm of Borges’ erudition and narrative poetics, as well as with certain « counter-Borgesian » constellations in recent Argentine literature. My reading aims to show how Chitarroni’s anti-novel reactivates a specific Argentinean tradition of productive illegibility while considering how it relates to the practices of « impediment » and « aesthetic reduction » that pervade modern art and literature. N2 - Este ensayo explora la poética de la opacidad en la escritura de Luis Chitarroni y en particular en su « novela inconclusa » Peripecias del no. El análisis se enfoca en la erudición « denegante » que distingue a este texto, y en su diálogo con el modelo de la erudición borgiana y con su poética narrativa, así como con una serie de líneas « contraborgianas » en la literatura argentina reciente. Mi lectura se orienta a mostrar cómo la anti-novela de Chitarroni reactiva una específica tradición literaria argentina de poéticas de lo ilegible a la vez que enlaza con las prácticas del « impedimento » y de la « reducción estética » que recorren la modernidad artística y literaria. N2 - Cet article explore la poétique de la opacité mise en jeu par Luis Chitarroni dans son « roman inachevé » Aventures du Non. À partir d’une analyse de l’érudition « reticente » inhérente à ce texte, j’examine le dialogue que Chitarroni établit avec le modèle de l’érudition borgésienne et sa poétique du récit, ainsi qu’avec une série de lignes narratives « post-borgésiennes » dans la littérature argentine récente. Ma lecture vise à montrer comment l’« anti-roman » de Chitarroni réactive une particulière tradition littéraire argentine relative aux poétiques de l’illisible tout en se liant à la fois avec les pratiques de l’« empêchement » narratif et de la « réduction esthétique » qui traversent la modernité artistique et littéraire. KW - poetics of the illegible KW - hermeticism KW - Chitarroni KW - Borges KW - modern art Y1 - 2017 UR - http://journals.openedition.org/lirico/3807 U6 - https://doi.org/10.4000/lirico.3807 SN - 2263-2158 SN - 2262-8339 PB - Universität de Paris CY - Saint-Denis ER - TY - GEN A1 - Fabian, Benjamin A1 - Baumann, Annika A1 - Ehlert, Mathias A1 - Ververis, Vasilis A1 - Ermakova, Tatiana T1 - CORIA - Analyzing internet connectivity risks using network graphs T2 - 2017 IEEE International Conference on Communications (ICC) N2 - The Internet can be considered as the most important infrastructure for modern society and businesses. A loss of Internet connectivity has strong negative financial impacts for businesses and economies. Therefore, assessing Internet connectivity, in particular beyond their own premises and area of direct control, is of growing importance in the face of potential failures, accidents, and malicious attacks. This paper presents CORIA, a software framework for an easy analysis of connectivity risks based on large network graphs. It provides researchers, risk analysts, network managers and security consultants with a tool to assess an organization's connectivity and paths options through the Internet backbone, including a user-friendly and insightful visual representation of results. CORIA is flexibly extensible in terms of novel data sets, graph metrics, and risk scores that enable further use cases. The performance of CORIA is evaluated by several experiments on the Internet graph and further randomly generated networks. KW - risk analysis KW - connectivity KW - graph analysis KW - complex networks KW - Internet Y1 - 2017 SN - 978-1-4673-8999-0 SN - 978-1-4673-9000-2 U6 - https://doi.org/10.1109/ICC.2017.7996828 SN - 1550-3607 PB - IEEE CY - Piscataway ER - TY - GEN A1 - Grossi, Giuseppe A1 - Reichard, Christoph A1 - Thomasson, Anna A1 - Vakkuri, Jarmo T1 - Editorial T2 - Public money & management : integrating theory and practice in public management Y1 - 2017 U6 - https://doi.org/10.1080/09540962.2017.1344007 SN - 0954-0962 SN - 1467-9302 VL - 37 SP - 379 EP - 386 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - GEN A1 - Hass, Roland A1 - Sandmann, Michael A1 - Reich, Oliver T1 - Photonic sensing in highly concentrated biotechnical processes by photon density wave spectroscopy T2 - Proceedings SPIE 10323, 25th International Conference on Optical Fiber Sensors N2 - Photon Density Wave (PDW) spectroscopy is introduced as a new approach for photonic sensing in highly concentrated biotechnical processes. It independently quantifies the absorption and reduced scattering coefficient calibration-free and as a function of time, thus describing the optical properties in the vis/NIR range of the biomaterial during their processing. As examples of industrial relevance, enzymatic milk coagulation, beer mashing, and algae cultivation in photo bioreactors are discussed. KW - Photon Density Wave Spectroscopy KW - multiple light scattering KW - fermentation KW - algae cultivation KW - process analytical technology KW - fiber spectroscopy Y1 - 2017 SN - 978-1-5090-4850-2 U6 - https://doi.org/10.1117/12.2263617 SN - 0277-786X SN - 1996-756X VL - 10323 PB - IEEE CY - New York ER - TY - JOUR A1 - Schmidt, Marco F. T1 - miRNA Targeting Drugs BT - the next blockbusters? JF - Drug Target miRNA: Methods and Protocols N2 - Only 20 years after the discovery of small non-coding, single-stranded ribonucleic acids, so-called microRNAs (miRNAs), as post-transcriptional gene regulators, the first miRNA-targeting drug Miravirsen for the treatment of hepatitis C has been successfully tested in clinical Phase II trials. Addressing miRNAs as drug targets may enable the cure, or at least the treatment of diseases, which presently seems impossible. However, due to miRNAs’ chemical structure, generation of potential drug molecules with necessary pharmacokinetic properties is still challenging and requires a re-thinking of the drug discovery process. Therefore, this chapter highlights the potential of miRNAs as drug targets, discusses the challenges, and tries to give a complete overview of recent strategies in miRNA drug discovery. KW - miRNA KW - Drug discovery KW - microRNA-induced silencing complex KW - Antisense agents KW - Small-molecule miRNA modulators KW - Argonaute 2 protein Y1 - 2016 SN - 978-1-4939-6563-2 SN - 978-1-4939-6561-8 U6 - https://doi.org/10.1007/978-1-4939-6563-2_1 SN - 1064-3745 SN - 1940-6029 VL - 1517 SP - 3 EP - 22 PB - Springer CY - New York ER - TY - JOUR A1 - Atilaw, Yoseph A1 - Duffy, Sandra A1 - Heydenreich, Matthias A1 - Muiva-Mutisya, Lois A1 - Avery, Vicky M. A1 - Erdelyi, Mate A1 - Yenesew, Abiy T1 - Three Chalconoids and a Pterocarpene from the Roots of Tephrosia aequilata JF - Molecules N2 - In our search for new antiplasmodial agents, the CH2Cl2/CH3OH (1:1) extract of the roots of Tephrosia aequilata was investigated, and observed to cause 100% mortality of the chloroquine-sensitive (3D7) strain of Plasmodium falciparum at a 10 mg/mL concentration. From this extract three new chalconoids, E-2,6-dimethoxy-3,4-(2,2-dimethyl)pyranoretrochalcone (1, aequichalcone A), Z-2,6-dimethoxy-3,4-(2,2-dimethyl)pyranoretrochalcone (2, aequichalcone B), 4-ethoxy-3-hydroxypraecansone B (3, aequichalcone C) and a new pterocarpene, 3,4:8,9-dimethylenedioxy-6a,11a-pterocarpene (4), along with seven known compounds were isolated. The purified compounds were characterized by NMR spectroscopic and mass spectrometric analyses. Compound 1 slowly converts into 2 in solution, and thus the latter may have been enriched, or formed, during the extraction and separation process. The isomeric compounds 1 and 2 were both observed in the crude extract. Some of the isolated constituents showed good to moderate antiplasmodial activity against the chloroquine-sensitive (3D7) strain of Plasmodium falciparum. KW - Tephrosia aequilata KW - chalcone KW - retrochalcone KW - aequichalcone A KW - aequichalcone B KW - aequichalcone C KW - pterocarpene KW - antiplasmodial Y1 - 2017 U6 - https://doi.org/10.3390/molecules22020318 SN - 1420-3049 VL - 22 IS - 2 PB - MDPI CY - Basel ER - TY - JOUR A1 - Nishino, Takeshi A1 - Okamoto, Ken A1 - Leimkühler, Silke T1 - Enzymes of the Xanthine Oxidase Family JF - Molybdenum and tungsten enzymes : biochemistry N2 - Enzymes from the xanthine oxidase (XO) family of molybdenum enzymes are generally, with some exceptions, molybdenum iron–sulfur flavin hydroxylases. Mammalian xanthine oxidoreductase and aldehyde oxidase were among the first enzymes to be studied in detail more than 100 years ago and, surprisingly, they continue to be thoroughly studied in molecular detail with many open and unresolved questions remaining. Enzymes of the XO family are characterized by a molybdenum cofactor (Moco) active site with a MoVIOS(OH) ligand sphere where substrate hydroxylation of either aromatic or aliphatic carbon centers is catalyzed. During the reaction, electrons are transferred to the oxidizing substrate, most commonly O2 or NAD+, which react at the FAD site. Y1 - 2016 SN - 978-1-78262-391-5 SN - 978-1-78262-089-1 SN - 978-1-78262-881-1 U6 - https://doi.org/10.1039/9781782623915-00192 VL - 5 SP - 192 EP - 239 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Leimkühler, Silke A1 - Lemaire, Olivier N. A1 - Iobbi-Nivol, Chantal T1 - Bacterial Molybdoenzymes BT - Chaperones, Assembly and Insertion JF - Molybdenum and tungsten enzymes : biochemistry N2 - The biogenesis of molybdoenzymes is a cytoplasmic event requiring both the folded apoenzymes and the matured molybdenum cofactor. The structure and the complexity of the molybdenum cofactor varies in each molybdoenzyme family and consequently different accessory proteins are required for the maturation of the respective enzymes. Thus, for enzymes of both the DMSO reductase and xanthine oxidase families, specific chaperones exist which are dedicated to increase the stability and the folding of specific members of each family. In this review, we describe the role of these chaperones for molybdoenzyme maturation. We present a model which describes step by step the mechanism of the maturation of representative molybdoenzymes from each family. Y1 - 2016 SN - 978-1-78262-391-5 SN - 978-1-78262-089-1 U6 - https://doi.org/10.1039/9781782623915-00117 VL - 5 SP - 117 EP - 142 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Leimkühler, Silke A1 - Mendel, Ralf-Rainer T1 - Molybdenum Cofactor Biosynthesis JF - Molybdenum and tungsten enzymes: biochemistry N2 - The biosynthesis of the molybdenum cofactor (Moco) is highly conserved among all kingdoms of life. In all molybdoenzymes with the exception of nitrogenase, the molybdenum atom is coordinated to a dithiolene group present in the pterin-based 6-alkyl side chain of molybdopterin (MPT). In general, the biosynthesis of Moco can be divided into three steps in eukaryotes, and four steps in bacteria and archaea: (i) the starting point is the formation of the cyclic pyranopterin monophosphate (cPMP) from 5′GTP, (ii) in the second step the two sulfur molecules are inserted into cPMP leading to the formation of MPT, (iii) in the third step the molybdenum atom is inserted into molybdopterin to form Moco and (iv) additional modification of Moco occurs in bacteria and archaea with the attachment of a nucleotide (CMP or GMP) to the phosphate group of MPT, forming the dinucleotide variants of Moco. This review will focus on the biosynthesis of Moco in bacteria, humans and plants. Y1 - 2016 SN - 978-1-78262-391-5 SN - 978-1-78262-089-1 SN - 978-1-78262-881-1 U6 - https://doi.org/10.1039/9781782623915 VL - 5 SP - 100 EP - 116 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Kühne, Franziska A1 - Maas, Jana A1 - Wiesenthal, Sophia A1 - Weck, Florian T1 - Supervision in der Verhaltenstherapie T1 - Supervision in behavioral therapy BT - ein Scoping Review zur Identifikation von Forschungszielen BT - a scoping review for identification of research objectives JF - Zeitschrift für klinische Psychologie und Psychotherapie : Forschung und Praxis N2 - Theoretischer Hintergrund:Supervision spielt eine zentrale Rolle zum Wissens- und Kompetenzerwerb sowie in der Qualitätssicherung. Fragestellung:Ziel war es, den aktuellen Forschungsstand zur Supervision im Rahmen der kognitiven Verhaltenstherapie abzubilden, um daraus Schlussfolgerungen für die zukünftige Forschung abzuleiten. Methode:Zur Evidenzsynthese wurde ein Scoping Review durchgeführt, das die Darstellung zentraler Konzepte, aktueller Evidenz und möglicher Forschungsbedarfe ermöglichte. Neben einer systematischen Literaturrecherche wurden Vorwärts- und Rückwärtssuchstrategien eingesetzt. Ergebnisse:Eingeschlossen wurden zwölf Publikationen basierend auf zehn empirischen Studien. Alle Studien beschrieben Ausbildungssettings, aber nur wenige untersuchten übende Interventionen (z. B. Rollenspiele). Häufig wurden Effekte subjektiv erfasst, die methodische Qualität der Begleitstudien variierte. Schlussfolgerungen:Notwendig sind weitere methodisch hochwertige Studien, experimentell orientiert oder in der klinischen Praxis, die die Supervisionsforschung bereichern können. N2 - Background:Supervision plays a central role for the acquisition of therapeutic knowledge and competence and for quality control. Objective:The study aimed at mapping the current evidence regarding cognitive–behavioral supervision, and drawing conclusions for future research. Method:For evidence synthesis, we conducted a scoping review to outline key concepts, the current evidence, and potential gaps in research. In addition to a systematic literature search, forward and backward search strategies were implemented. Results:We included 12 publications on 10 empirical studies. All studies referred to education and training, but only a few examined exercises (e. g., role plays). Mostly, outcomes were evaluated subjectively, and study quality varied. Conclusion:Further methodologically sound studies, experimentally oriented or in clinical care, may support research. KW - clinical supervision KW - review KW - scoping study KW - cognitive behavioral therapy KW - psychotherapy KW - klinische Supervision KW - Übersichtsarbeit KW - kognitive Verhaltenstheraphie KW - Psychoterapie Y1 - 2017 U6 - https://doi.org/10.1026/1616-3443/a000414 SN - 1616-3443 SN - 2190-6297 VL - 46 IS - 2 SP - 73 EP - 82 PB - Hogrefe CY - Göttingen ER - TY - JOUR A1 - Sander, Martha Maria A1 - Eccard, Jana A1 - Heim, Wieland T1 - Flight range estimation of migrant yellow-browed warblers phylloscopus inornatus on the East Asian flyway JF - Bird study : the journal of the British Trust for Ornithology N2 - Fat loads were quantified for 2125 Yellow-browed Warblers Phylloscopus inornatus trapped at a stop-over site in Far East Russia during autumn migration. Flight ranges of 660-820km were estimated for the fattest individuals, suggesting that they would need to stop for refuelling at least six times to reach their wintering areas in South East Asia. Y1 - 2017 U6 - https://doi.org/10.1080/00063657.2017.1409696 SN - 0006-3657 SN - 1944-6705 VL - 64 SP - 569 EP - 572 PB - Taylor & Francis CY - Abingdon ER - TY - JOUR A1 - Apelojg, Benjamin ED - Apelojg, Benjamin ED - Banse, Gerhard T1 - Innovationen als Element einer zukunftsweisenden ökonomischen und technischen Bildung JF - Technische Bildung und berufliche Orientierung im Wandel - Rückblicke, Einblicke, Ausblicke N2 - Innovationen sind wie ein Motor, der unser ökonomisches, soziales und ge-sellschaftliches Leben antreibt und laufend verändert. Ob in der Medizin-technik, Luft- und Raumfahrt, Energiegewinnung, im Netz oder in der Schule: In allen Bereichen sorgen Innovationen für die stetige Weiterent-wicklung unser Gesellschaft. Bernd Meier hat die Bedeutung von Innova-tionen und innovativem Denken für die technische Bildung und Schule früh erkannt. Mit einer kurzen Rückschau auf sein Wirken hinsichtlich der Be-deutung von Innovationen für die technische und ökonomische Bildung soll ein wichtiger Bereich seiner Arbeit gewürdigt werden. Zu Beginn wird der Innovationsbegriff allgemein umrissen und dann mit Blick auf Schule präzi-siert. Danach wird dargestellt, welchen Stellenwert die Thematik Innovation und Technologie nicht nur in den Publikationen von Bernd Meier, sondern auch in seinen Lehrkonzeptionen eingenommen hat. Im Anschluss daran wird diskutiert, warum es gerade im Bildungsbereich so schwer ist, innova-tiv zu sein oder dauerhaft Innovationen durchzusetzen.1 Der Beitrag endet mit einem Ausblick, inwiefern Innovationen auch in Zukunft für Schule und das Fach Wirtschaft-Arbeit-Technik (kurz: WAT) eine wichtige Thematik darstellen sollten. Y1 - 2017 SN - 978-3-86464-156-5 VL - 133/134 SP - 95 EP - 107 PB - Trafo-Verlag CY - Berlin ER -