TY  - JOUR
A1  - Petrović, Saša
A1  - Wendler, Petra
T1  - A RADD approach to probing AAA plus protein function
JF  - Nature structural & molecular biology
N2  - AAA+ proteins (ATPases associated with various cellular activities) catalyze the energy-dependent movement or rearrangement of macromolecules. A new study addresses the important question of how to design a selective chemical inhibitor for specific proteins in this diverse superfamily. The powerful chemical genetics approach adds to a growing toolbox of applications that allow dissection of the functions of distinct AAA+ proteins in vivo, facilitating the first steps toward effective drug development.
Y1  - 2021
U6  - https://doi.org/10.1038/s41594-021-00579-5
SN  - 1545-9993
SN  - 1545-9985
VL  - 28
IS  - 4
SP  - 329
EP  - 330
PB  - Nature Publishing Group
CY  - Berlin
ER  -