TY - JOUR A1 - Rogge, B. A1 - Itagaki, Y. A1 - Fishkin, N. A1 - Levi, E. A1 - Ruhl, R. A1 - Yi, S. S. A1 - Nakanishi, K. A1 - Hammerling, U. T1 - Retinoylserine and retinoylalanine, natural products of the moth Trichoplusia ni N2 - Insect cells convert vitamin A into a number of retinoids that are evolutionarily conserved with those of mammalian cells. However, insect cells also produce additional natural retinoids. Namely, two retinoic acid peptides, N- trans-retinoylserine (1) and N-trans-retinoylalanine (2), have been isolated from a cell line of the common cabbage looper, Trichoplusia ni. These are the first examples of naturally occurring retinoic acid linked to amino acids through an amide bond; the amino acid moieties are depicted in the more common L-configuration, although the absolute configuration was not determined due to the minuscule sample amount Y1 - 2005 SN - 0163-3864 ER -