TY  - JOUR
A1  - Fritzsch, Claire
A1  - Wang, Jing
A1  - dos Santos, Luara Ferreira
A1  - Mauritz, Karl-Heinz
A1  - Brunetti, Maddalena
A1  - Dohle, Christian
T1  - Different effects of the mirror illusion on motor and somatosensory processing
JF  - Restorative neurology and neuroscience
N2  - Purpose: Mirror therapy can improve motor and sensory functions, but effects of the mirror illusion on primary motor and somatosensory cortex could not be established consistently.
 Methods: Fifteen right handed healthy volunteers performed or observed a finger-thumb opposition task. Cerebral activations during normal movement (NOR), mirrored movement (MIR) and movement observation (OBS) by means of a video chain were recorded with functional magnetic resonance imaging (fMRI). Activation sizes in movement > static conditions were identified using SPM8 (p < 0.001, unc.) and attributed to predefined areas employing the Anatomy toolbox 1.8. Laterality indices for the responsive areas were calculated on the basis of the number of activated voxels.
 Results: Relevant bilateral BOLD responses were found in primary motor (M1) and somatosensory (S1 - BA 2, 3b and 3a) cortex, premotor and parietal areas and V5. When comparing MIR to NOR, no significant change of contralateral activation in M1 was found, but clearly at S1 with differences between hands.
 Conclusion: The mirror illusion does not elicit immediate changes in motor areas, yet there is a direct effect on somatosensory areas, especially for left hand movements. These results suggest different effects of mirror therapy on processing and rehabilitation of motor and sensory function.
KW  - Movement
KW  - mirror
KW  - laterality
KW  - stroke
KW  - sensorimotor cortex
Y1  - 2014
U6  - https://doi.org/10.3233/RNN-130343
SN  - 0922-6028
SN  - 1878-3627
VL  - 32
IS  - 2
SP  - 269
EP  - 280
PB  - IOS Press
CY  - Amsterdam
ER  -