TY  - JOUR
A1  - Sulpice, Ronan
A1  - Pyl, Eva-Theresa
A1  - Ishihara, Hirofumi
A1  - Trenkamp, Sandra
A1  - Steinfath, Matthias
A1  - Witucka-Wall, Hanna
A1  - Gibon, Yves
A1  - Usadel, Björn
A1  - Poree, Fabien
A1  - Piques, Maria Conceicao
A1  - von Korff, Maria
A1  - Steinhauser, Marie Caroline
A1  - Keurentjes, Joost J. B.
A1  - Guenther, Manuela
A1  - Hoehne, Melanie
A1  - Selbig, Joachim
A1  - Fernie, Alisdair R.
A1  - Altmann, Thomas
A1  - Stitt, Mark
T1  - Starch as a major integrator in the regulation of plant growth
N2  - Rising demand for food and bioenergy makes it imperative to breed for increased crop yield. Vegetative plant growth could be driven by resource acquisition or developmental programs. Metabolite profiling in 94 Arabidopsis accessions revealed that biomass correlates negatively with many metabolites, especially starch. Starch accumulates in the light and is degraded at night to provide a sustained supply of carbon for growth. Multivariate analysis revealed that starch is an integrator of the overall metabolic response. We hypothesized that this reflects variation in a regulatory network that balances growth with the carbon supply. Transcript profiling in 21 accessions revealed coordinated changes of transcripts of more than 70 carbon-regulated genes and identified 2 genes (myo-inositol-1- phosphate synthase, a Kelch-domain protein) whose transcripts correlate with biomass. The impact of allelic variation at these 2 loci was shown by association mapping, identifying them as candidate lead genes with the potential to increase biomass production.
Y1  - 2009
UR  - http://www.pnas.org/
U6  - https://doi.org/10.1073/pnas.0903478106
SN  - 0027-8424
ER  -