TY - JOUR A1 - Ghods, Mojtaba A1 - Georgiou, Iakovos A1 - Schmidt, Jeremias A1 - Kruppa, Philipp T1 - Disease progression and comorbidities in lipedema patients BT - a 10-year retrospective analysis JF - Dermatologic therapy N2 - Multiple associated comorbidities have been described for lipedema patients. Disease diagnosis still remains challenging in many cases and is frequently delayed. The purpose of this study was to determine the most common comorbidities in lipedema patients and the impact of surgical treatment onto disease progression. A retrospective assessment of disease-related epidemiologic data was performed for patients who underwent liposuction between July 2009 and July 2019 in a specialized clinic for lipedema surgery. All patients received a standardized questionnaire regarding the clinical history and changes of lipedema-associated symptoms and comorbidities after surgery. 106 patients who underwent a total of 298 liposuction procedures were included in this study after returning the questionnaire fully filled-in. Multiple comorbidities were observed in the assessed collective. The prevalence for obesity, hypothyroidism, migraine, and depression were markedly increased in relation to comparable nonlipedema populations. Despite a median body mass index (BMI) of 31.6 kg/m(2) (IQR 26.4-38.8), unexpected low prevalence of diabetes (5%) and dyslipidemia (7%) was found. Diagnosis and initiation of guideline-appropriate treatment were delayed by years in many patients. After surgical treatment (medium follow-up 20 months, IQR 11-42), a significant reduction of lipedema-associated symptoms was demonstrated. Lipedema occurs with a diversity of associated comorbidities. Therefore, on the basis of available data, the authors suggest the necessity of a multimodal therapy concept for a comprehensive and holistic treatment. Despite a commonly increased BMI, lipedema patients appear to have an advantageous metabolic risk profile. KW - comorbidities KW - epidemiology KW - lipedema KW - lipoedema KW - subcutaneous adipose tissue Y1 - 2020 U6 - https://doi.org/10.1111/dth.14534 SN - 1529-8019 VL - 33 IS - 6 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Georgiou, Iakovos A1 - Kruppa, Philipp A1 - Schmidt, Jeremias A1 - Ghods, Mojtaba T1 - Liposuction for Lipoedema BT - functional therapy or aesthetic procedure? JF - Aesthetic plastic surgery : official journal of the International Society of Aesthetic Plastic Surgery ; official publication of the Lipoplasty Society of North America N2 - Liposuction is one of the most common procedures undertaken in plastic surgery with a steadily increasing trend over the years. Although usually performed as an aesthetic procedure for body contouring, it can also be utilized in specific patient groups for disease symptom reduction. One such disease entity is lipedema. The goal of this video to present the authors' technique in the surgical treatment of lipedema, and to offer the viewer a better understanding of the differences between an aesthetic liposuction and a functional liposuction as performed on a lipedema patient. Between July 2009 and July 2019, 106 lipedema patients have been treated in the authors' specialized lipedema clinic, with a total of 298 liposuction procedures and a median follow-up of 20 months. The mean amount of lipoaspirate was 6354.73 ml (+/- 2796.72 ml). The patients reported a significant reduction in lipedema-associated complaints and improvement in quality of life. The need for conservative therapy was significantly reduced. No serious complications were reported. The authors also present before and after photographs of three patients. KW - Lipedema KW - Lipoedema KW - Liposuction KW - Megaliposuction Y1 - 2020 U6 - https://doi.org/10.1007/s00266-020-01910-z SN - 0364-216X SN - 1432-5241 VL - 45 SP - 212 EP - 213 PB - Springer CY - New York ER -