TY  - GEN
A1  - Alirezaeizanjani, Zahra
A1  - Großmann, Robert
A1  - Pfeifer, Veronika
A1  - Hintsche, Marius
A1  - Beta, Carsten
T1  - Chemotaxis strategies of bacteria with multiple run modes
T2  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Bacterial chemotaxis-a fundamental example of directional navigation in the living world-is key to many biological processes, including the spreading of bacterial infections. Many bacterial species were recently reported to exhibit several distinct swimming modes-the flagella may, for example, push the cell body or wrap around it. How do the different run modes shape the chemotaxis strategy of a multimode swimmer? Here, we investigate chemotactic motion of the soil bacterium Pseudomonas putida as a model organism. By simultaneously tracking the position of the cell body and the configuration of its flagella, we demonstrate that individual run modes show different chemotactic responses in nutrition gradients and, thus, constitute distinct behavioral states. On the basis of an active particle model, we demonstrate that switching between multiple run states that differ in their speed and responsiveness provides the basis for robust and efficient chemotaxis in complex natural habitats.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1418 
KW  - instability
KW  - flagellum
KW  - exploit
KW  - time
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-519098
SN  - 1866-8372
IS  - 22
ER  - 
TY  - JOUR
A1  - Gómez-Nava, Luis
A1  - Grossmann, Robert
A1  - Hintsche, Marius
A1  - Beta, Carsten
A1  - Peruani, Fernando
T1  - A novel approach to chemotaxis
BT  - active particles guided by internal clocks
JF  - epl : a letters journal exploring the frontiers of physics
N2  - Motivated by the observation of non-exponential run-time distributions of bacterial swimmers, we propose a minimal phenomenological model for taxis of active particles whose motion is controlled by an internal clock. The ticking of the clock depends on an external concentration field, e.g., a chemical substance. We demonstrate that these particles can detect concentration gradients and respond to them by moving up- or down-gradient depending on the clock design, albeit measurements of these fields are purely local in space and instantaneous in time. Altogether, our results open a new route in the study of directional navigation: we show that the use of a clock to control motility actions represents a generic and versatile toolbox to engineer behavioral responses to external cues, such as light, chemical, or temperature gradients.
Y1  - 2020
U6  - https://doi.org/10.1209/0295-5075/130/68002
SN  - 0295-5075
SN  - 1286-4854
VL  - 130
IS  - 6
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Alirezaeizanjani, Zahra
A1  - Großmann, Robert
A1  - Pfeifer, Veronika
A1  - Hintsche, Marius
A1  - Beta, Carsten
T1  - Chemotaxis strategies of bacteria with multiple run modes
JF  - Science advances
N2  - Bacterial chemotaxis-a fundamental example of directional navigation in the living world-is key to many biological processes, including the spreading of bacterial infections. Many bacterial species were recently reported to exhibit several distinct swimming modes-the flagella may, for example, push the cell body or wrap around it. How do the different run modes shape the chemotaxis strategy of a multimode swimmer? Here, we investigate chemotactic motion of the soil bacterium Pseudomonas putida as a model organism. By simultaneously tracking the position of the cell body and the configuration of its flagella, we demonstrate that individual run modes show different chemotactic responses in nutrition gradients and, thus, constitute distinct behavioral states. On the basis of an active particle model, we demonstrate that switching between multiple run states that differ in their speed and responsiveness provides the basis for robust and efficient chemotaxis in complex natural habitats.
KW  - exploit
KW  - flagellum
KW  - instability
KW  - time
Y1  - 2020
U6  - https://doi.org/10.1126/sciadv.aaz6153
SN  - 2375-2548
VL  - 6
IS  - 22
PB  - American Association for the Advancement of Science
CY  - Washington
ER  -