TY - JOUR A1 - Hänel, Hilkje C. T1 - (Moralisch) guter Sex T1 - (Morally) good sex BT - eine Kritik am Zustimmungsmodell BT - a critique of the consent model JF - Zeitschrift für Praktische Philosophie N2 - In einem kürzlich erschienenen Artikel argumentiert Almut v. Wedelstaedt überzeugend, warum Zustimmung zwar „die Bedingung für die Legitimation von Sex“ ist (2020, 127), dass die moralische Güte von Sex aber nur dann einzuschätzen ist, wenn wir darauf achten, ob die Beteiligten der Handlung sich auf Augenhöhe begegnen. Die Idee ist: Es gibt legitime sexuelle Handlungen, die moralisch gut sind, und es gibt legitime sexuelle Handlungen, die moralisch besser sind. Hier möchte ich die Idee des besseren Sexes genauer ausloten. Während v. Wedelstaedt von moralisch gelungenem Sex spricht und somit auf der Ebene der moralischen Bewertung von Sex bleibt, möchte ich die Frage danach stellen, was Sex qualitativ gut macht. Tatsächlich wird in der Zustimmungsdebatte meist davon ausgegangen, dass diese zwei Fragen wenig gemeinsam haben; ob eine sexuelle Handlung legitim ist, hat zunächst nichts damit zu tun, ob diese auch gut ist. Ich werde drei Argumente liefern, warum wir legitimen Sex und qualitativ guten Sex zusammen betrachten sollten – und es wird sich zeigen, dass die gegenwärtige philosophische und rechtstheoretische Debatte Zustimmung verkürzt diskutiert und daher alleingenommen wenig hilfreich ist, stattdessen benötigt die Zustimmungsdebatte auch eine Untersuchung von qualitativ gutem Sex. N2 - In a recent article, Almut v. Wedelstaedt argues convincingly why consent is “the condition for the legitimation of sex” (2020, 127; my translation), but that the moral goodness of sex can only be assessed if we pay attention to whether the participants in the act meet on an equal footing; the consent criterion, v. Wedelstaedt argues, must therefore be supplemented by another criterion, namely that of equal footing. The idea is: there are legitimate sexual acts that are morally good, and there are legitimate sexual acts that are morally better. Here I would like to explore the idea of better sex in more detail. While v. Wedelstaedt speaks of morally successful sex, and thus remains on the level of moral evaluation of sex, I would like to raise the question of what makes sex qualitatively good. Indeed, the consent debate usually assumes that these two questions have little in common; whether a sexual act is legitimate has nothing to do with whether it is good to begin with. I will provide three arguments why we should consider legitimate sex and qualitatively good sex together, and it will become apparent that the current philosophical and legal theory debate discusses consent in a truncated way, and therefore taken alone, is unhelpful; instead, the consent debate also needs an examination of qualitatively good sex. KW - Sex KW - Zustimmung KW - sexuelle Handlungsfähigkeit KW - sexistische Ideologie KW - sexuelle Gewalt KW - sex KW - consent KW - sexual agency KW - sexist ideology KW - sexual violence Y1 - 2023 U6 - https://doi.org/10.22613/zfpp/9.2.2 SN - 2409-9961 VL - 9 IS - 2 SP - 49 EP - 78 PB - Universität Salzburg CY - Salzburg ER - TY - JOUR A1 - Koenig, Julian A1 - Abler, Birgit A1 - Agartz, Ingrid A1 - akerstedt, Torbjorn A1 - Andreassen, Ole A. A1 - Anthony, Mia A1 - Baer, Karl-Juergen A1 - Bertsch, Katja A1 - Brown, Rebecca C. A1 - Brunner, Romuald A1 - Carnevali, Luca A1 - Critchley, Hugo D. A1 - Cullen, Kathryn R. A1 - de Geus, Eco J. C. A1 - de la Cruz, Feliberto A1 - Dziobek, Isabel A1 - Ferger, Marc D. A1 - Fischer, Hakan A1 - Flor, Herta A1 - Gaebler, Michael A1 - Gianaros, Peter J. A1 - Giummarra, Melita J. A1 - Greening, Steven G. A1 - Guendelman, Simon A1 - Heathers, James A. J. A1 - Herpertz, Sabine C. A1 - Hu, Mandy X. A1 - Jentschke, Sebastian A1 - Kaess, Michael A1 - Kaufmann, Tobias A1 - Klimes-Dougan, Bonnie A1 - Koelsch, Stefan A1 - Krauch, Marlene A1 - Kumral, Deniz A1 - Lamers, Femke A1 - Lee, Tae-Ho A1 - Lekander, Mats A1 - Lin, Feng A1 - Lotze, Martin A1 - Makovac, Elena A1 - Mancini, Matteo A1 - Mancke, Falk A1 - Mansson, Kristoffer N. T. A1 - Manuck, Stephen B. A1 - Mather, Mara A1 - Meeten, Frances A1 - Min, Jungwon A1 - Mueller, Bryon A1 - Muench, Vera A1 - Nees, Frauke A1 - Nga, Lin A1 - Nilsonne, Gustav A1 - Ordonez Acuna, Daniela A1 - Osnes, Berge A1 - Ottaviani, Cristina A1 - Penninx, Brenda W. J. H. A1 - Ponzio, Allison A1 - Poudel, Govinda R. A1 - Reinelt, Janis A1 - Ren, Ping A1 - Sakaki, Michiko A1 - Schumann, Andy A1 - Sorensen, Lin A1 - Specht, Karsten A1 - Straub, Joana A1 - Tamm, Sandra A1 - Thai, Michelle A1 - Thayer, Julian F. A1 - Ubani, Benjamin A1 - van Der Mee, Denise J. A1 - van Velzen, Laura S. A1 - Ventura-Bort, Carlos A1 - Villringer, Arno A1 - Watson, David R. A1 - Wei, Luqing A1 - Wendt, Julia A1 - Schreiner, Melinda Westlund A1 - Westlye, Lars T. A1 - Weymar, Mathias A1 - Winkelmann, Tobias A1 - Wu, Guo-Rong A1 - Yoo, Hyun Joo A1 - Quintana, Daniel S. T1 - Cortical thickness and resting-state cardiac function across the lifespan BT - a cross-sectional pooled mega-analysis JF - Psychophysiology : journal of the Society for Psychophysiological Research N2 - Understanding the association between autonomic nervous system [ANS] function and brain morphology across the lifespan provides important insights into neurovisceral mechanisms underlying health and disease. Resting-state ANS activity, indexed by measures of heart rate [HR] and its variability [HRV] has been associated with brain morphology, particularly cortical thickness [CT]. While findings have been mixed regarding the anatomical distribution and direction of the associations, these inconsistencies may be due to sex and age differences in HR/HRV and CT. Previous studies have been limited by small sample sizes, which impede the assessment of sex differences and aging effects on the association between ANS function and CT. To overcome these limitations, 20 groups worldwide contributed data collected under similar protocols of CT assessment and HR/HRV recording to be pooled in a mega-analysis (N = 1,218 (50.5% female), mean age 36.7 years (range: 12-87)). Findings suggest a decline in HRV as well as CT with increasing age. CT, particularly in the orbitofrontal cortex, explained additional variance in HRV, beyond the effects of aging. This pattern of results may suggest that the decline in HRV with increasing age is related to a decline in orbitofrontal CT. These effects were independent of sex and specific to HRV; with no significant association between CT and HR. Greater CT across the adult lifespan may be vital for the maintenance of healthy cardiac regulation via the ANS-or greater cardiac vagal activity as indirectly reflected in HRV may slow brain atrophy. Findings reveal an important association between CT and cardiac parasympathetic activity with implications for healthy aging and longevity that should be studied further in longitudinal research. KW - aging KW - autonomic nervous system KW - cortical thickness KW - heart rate KW - heart KW - rate variability KW - sex Y1 - 2020 U6 - https://doi.org/10.1111/psyp.13688 SN - 0048-5772 SN - 1469-8986 VL - 58 IS - 7 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Winkelbeiner, Nicola Lisa A1 - Wandt, Viktoria Klara Veronika A1 - Ebert, Franziska A1 - Lossow, Kristina A1 - Bankoglu, Ezgi E. A1 - Martin, Maximilian A1 - Mangerich, Aswin A1 - Stopper, Helga A1 - Bornhorst, Julia A1 - Kipp, Anna Patricia A1 - Schwerdtle, Tanja T1 - A Multi-Endpoint Approach to Base Excision Repair Incision Activity Augmented by PARylation and DNA Damage Levels in Mice BT - Impact of Sex and Age JF - International Journal of Molecular Sciences N2 - Investigation of processes that contribute to the maintenance of genomic stability is one crucial factor in the attempt to understand mechanisms that facilitate ageing. The DNA damage response (DDR) and DNA repair mechanisms are crucial to safeguard the integrity of DNA and to prevent accumulation of persistent DNA damage. Among them, base excision repair (BER) plays a decisive role. BER is the major repair pathway for small oxidative base modifications and apurinic/apyrimidinic (AP) sites. We established a highly sensitive non-radioactive assay to measure BER incision activity in murine liver samples. Incision activity can be assessed towards the three DNA lesions 8-oxo-2’-deoxyguanosine (8-oxodG), 5-hydroxy-2’-deoxyuracil (5-OHdU), and an AP site analogue. We applied the established assay to murine livers of adult and old mice of both sexes. Furthermore, poly(ADP-ribosyl)ation (PARylation) was assessed, which is an important determinant in DDR and BER. Additionally, DNA damage levels were measured to examine the overall damage levels. No impact of ageing on the investigated endpoints in liver tissue were found. However, animal sex seems to be a significant impact factor, as evident by sex-dependent alterations in all endpoints investigated. Moreover, our results revealed interrelationships between the investigated endpoints indicative for the synergetic mode of action of the cellular DNA integrity maintaining machinery. KW - maintenance of genomic integrity KW - ageing KW - sex KW - DNA damage KW - base excision repair (incision activity) KW - DNA damage response KW - poly(ADP-ribosyl)ation KW - liver Y1 - 2020 U6 - https://doi.org/10.3390/ijms21186600 SN - 1422-0067 VL - 21 IS - 18 PB - Molecular Diversity Preservation International CY - Basel ER - TY - JOUR A1 - Kosman, Admiʾel T1 - The temptation in the garden of R. Hiyya bar Ashi and his wife JF - European Judaism N2 - The narrative in BT Kiddushin 81b about R. Hiyya bar Ashi tells of a sage who waged a battle with his Urge after he refrained from engaging in sexual relations with his wife. He, however, did not reveal to her the battle being waged within him, but rather pretended to be an ‘angel’. When his wife incidentally found it, she disguised herself as a harlot and set out to seduce him. After they had engaged in sexual relations, the rabbi wanted to commit suicide. The traditional readings view R. Hiyya as the hero of the tale. This article claims that the aim of the narrative is to present the rabbi as being carried away by dualistic-Christian conceptions. The article further argues that the topic of the narrative is not sexual relations, but dialogue. KW - asceticism KW - dialogue KW - evil inclination KW - gender KW - Judaism KW - sex KW - Talmud Y1 - 2017 U6 - https://doi.org/10.3167/ej.2017.500214 SN - 0014-3006 SN - 1752-2323 VL - 50 IS - 2 SP - 129 EP - 146 PB - Berghahn Journals CY - Brooklyn ER -