TY - JOUR A1 - Wiemann, Dirk T1 - Cities of the mind - villages of the mind BT - imagining urbanity in Contemporary India JF - Zeitschrift für Anglistik und Amerikanistik : a quarterly of language, literature and cultur N2 - Deep into the second half of the twentieth century the traditionalist definition of India as a country of villages remained dominant in official political rhetoric as well as cultural production. In the past two decades or so, this ruralist paradigm has been effectively superseded by a metropolitan imaginary in which the modern, globalised megacity increasingly functions as representative of India as a whole. Has the village, then, entirely vanished from the cultural imaginary in contemporary India? Addressing economic practices from upper-class consumerism to working-class family support strategies, this paper attempts to trace how 'the village' resurfaces or survives as a cultural reference point in the midst of the urban. Y1 - 2013 U6 - https://doi.org/10.1515/zaa.2013.61.1.59 SN - 0044-2305 VL - 61 IS - 1 SP - 59 EP - 72 PB - Königshausen & Neumann CY - Würzburg ER - TY - JOUR A1 - Sarrar, L. A1 - Warschburger, Petra A1 - Pfeiffer, E. A1 - Lehmkuhl, Ulrike A1 - Schneider, N. T1 - Cognitive flexibility in adolescent patients with unipolar affective disorders - gender differences JF - Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie N2 - Objective: Several studies have revealed impairments in cognitive functions among patients with affective disorders (AD). However, to date there are few neuropsychological studies on cognitive flexibility among adolescent patients with AD, especially on gender differences in AD. Here, we investigate cognitive functions, especially cognitive flexibility, in adolescent patients with unipolar AD (UAD) compared to a healthy control group (CG). Method: The study population consists of 17 male patients (M-age = 15.4 +/- 1.3) and 22 female patients with UAD (M-age = 15.6 +/- 1.4) as well as 20 male (M-age = 16.0 +/- 1.0) and 30 female (M-age = 15.7 +/- 0.9) healthy adolescents. A neuropsychological test battery was conducted, and depressive symptoms, psychological stress, and intelligence were also assessed. Results: The analyses revealed no significant group differences regarding cognitive flexibility or visual processing speed, albeit slight better performance in motor processing speed for the CG. Furthermore, no gender differences were observed regarding cognitive flexibility, though female subjects general displayed better performance in processing speed. Conclusions: Overall, there are no indications for serious deficits and specific gender differences in cognitive flexibility or processing speed in adolescent patients with UAD. Independent of psychological distress, female subjects seem to have some advantages in processing speed. KW - cognitive flexibility KW - unipolar affective disorders KW - sex differences KW - adolescents Y1 - 2013 U6 - https://doi.org/10.1024/1422-4917/a000240 SN - 1422-4917 VL - 41 IS - 4 SP - 261 EP - 270 PB - Hogrefe CY - Bern ER - TY - JOUR A1 - Nottebrock, Henning A1 - Esler, Karen J. A1 - Schurr, Frank Martin T1 - Effects of intraspecific and community density on the lifetime fecundity of long-lived shrubs JF - Perspectives in plant ecology, evolution and systematics N2 - Intra- and interspecific density dependence has profound consequences for plant population and community dynamics. In long-lived plants, however, lifetime patterns and mechanisms of density dependence are difficult to study. Here, we examine effects of intraspecific and community density on the lifetime fecundity of two long-lived shrub species from South African Fynbos: Protea repens (animal-pollinated, hermaphroditic) and Leucadendron rubrum (wind-pollinated, dioecious). Both species are serotinous, retaining seeds in cones until fire kills the mother plant. We measured lifetime fecundity as the product of cone number, proportion of cones that are not damaged by predation and seed set (fertile seeds per intact cone). Intraspecific and community densities were quantified by counting individuals of target species and all Proteaceae in small- and large-scale neighbourhoods (10 m and 50 m radius) around each focal individual. Additionally, we determined the age and size of focal individuals. We found that lifetime fecundity of the wind-pollinated L rubrum is density independent. In contrast, the lifetime fecundity of the animal-pollinated P. repens increases with large-scale intraspecific density and shows a hump-shaped relationship to large-scale community density. Community density has a hump-shaped effect on seed set (probably through partial absence of generalized pollinators at low and competition for pollinators at high densities) and negatively affects cone number per individual. For both species, plant age decreases seed set while increasing lifetime fecundity. The qualitative differences in the density dependence of lifetime fecundity may arise from differences between animal and wind pollination. In particular, interactions with generalized animal pollinators may cause community-level Allee effects with profound consequences for the future dynamics of long-lived plant populations and communities. KW - Competition KW - Community-level Allee effects KW - Facilitation KW - Fitness components KW - Interspecific interactions KW - Plant-animal interactions Y1 - 2013 U6 - https://doi.org/10.1016/j.ppees.2013.03.003 SN - 1433-8319 VL - 15 IS - 3 SP - 150 EP - 161 PB - Elsevier CY - Jena ER - TY - JOUR A1 - Hernandez de la Fuente, David T1 - The chorus of dionysus religion and education in Plato's Nomoi JF - Zeitschrift für Religions- und Geistesgeschichte Y1 - 2013 SN - 0044-3441 VL - 65 IS - 1 SP - 1 EP - 17 PB - Brill CY - Leiden ER - TY - JOUR A1 - Schaffner, Ellen A1 - Schiefele, Ulrich A1 - Schmidt, Meike T1 - The importance of family background for reading motivation and reading frequency of high school students JF - Zeitschrift für Entwicklungspsychologie und pädagogische Psychologie N2 - This article examines the relationships between family background and reading motivation (RM) as well as reading frequency in a sample of 156 high school students. To test the effects of family background (migration status, books at home, parents' appreciation of reading, parents' motivating practices), hierarchical regression analyses were applied. In these analyses, students' perceptions of reading incentives provided by the school and peer group were taken into account as control variables. Parents' learning-oriented appreciation of reading and motivating practices emerged as important predictors of intrinsic and extrinsic RM. Reading frequency was predicted by the number of books at home and parents' motivating practices. The effects of family background on extrinsic RM and reading frequency remained stable, even after controlling for reading incentives provided by the school and peer group. KW - reading motivation KW - reading frequency KW - family background Y1 - 2013 U6 - https://doi.org/10.1026/0049-8637/a000085 SN - 0049-8637 VL - 45 IS - 3 SP - 131 EP - 141 PB - Hogrefe CY - Göttingen ER - TY - JOUR A1 - Möller, Ingrid A1 - Krahé, Barbara A1 - Busching, Robert T1 - Consumption of media violence and aggressive behavior a longitudinal study of German adolescents with and without migration background JF - Zeitschrift für Entwicklungspsychologie und pädagogische Psychologie N2 - The consumption of media violence and aggressive behavior were assessed three times in a sample of N=1,052 German adolescents with and without migration background over a period of two years with 12-month intervals. The adolescents in the two groups, who were in grades 7 and 8 at T1, were matched by gender, age, type of school, and academic achievement. Students in the migrant group reported higher consumption of violent media. At T3, they showed more physical but less relational aggression than their peers of German background. Cross-lagged panel analyses showed parallel associations between media violence use and aggression in both groups: Media violence consumption at T1 and T2 predicted physical aggression at T2 and T3 independent of ethnic background. The reverse path from physical aggression to media violence consumption was nonsignificant. No link was found between media violence use and relational aggression over time. KW - media violence KW - aggression KW - migration KW - adolescence KW - longitudinal study Y1 - 2013 U6 - https://doi.org/10.1026/0049-8637/a000086 SN - 0049-8637 VL - 45 IS - 3 SP - 121 EP - 130 PB - Hogrefe CY - Göttingen ER - TY - JOUR A1 - Junginger, Mathias A1 - Kübel, Christian A1 - Schacher, Felix H. A1 - Müller, Axel H. E. A1 - Taubert, Andreas T1 - Crystal structure and chemical composition of biomimetic calcium phosphate nanofibers JF - RSC Advances N2 - Calcium phosphate nanofibers with a diameter of only a few nanometers and a cotton-ball-like aggregate morphology have been reported several times in the literature. Although fiber formation seems reproducible in a variety of conditions, the crystal structure and chemical composition of the fibers have been elusive. Using scanning transmission electron microscopy, low dose electron (nano) diffraction, energy-dispersive X-ray spectroscopy, and energy-filtered transmission electron microscopy, we have assigned crystal structures and chemical compositions to the fibers. Moreover, we demonstrate that the mineralization process yields true polymer/calcium phosphate hybrid materials where the block copolymer template is closely associated with the calcium phosphate. Y1 - 2013 U6 - https://doi.org/10.1039/c3ra23348k SN - 2046-2069 VL - 3 IS - 28 SP - 11301 EP - 11308 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Liang, Wei A1 - Heinrich, Ingo A1 - Helle, Gerhard A1 - Linan, Isabel Dorado A1 - Heinken, Thilo T1 - Applying CLSM to increment core surfaces for histometric analyses a novel advance in quantitative wood anatomy JF - Dendrochronologia : an interdisciplinary journal of tree-ring science N2 - A novel procedure has been developed to conduct cell structure measurements on increment core samples of conifers. The procedure combines readily available hardware and software equipment. The essential part of the procedure is the application of a confocal laser scanning microscope (CLSM) which captures images directly from increment cores surfaced with the advanced WSL core-microtome. Cell wall and lumen are displayed with a strong contrast due to the monochrome black and green nature of the images. Consecutive images are merged into long images representing entire increment cores which are then analysed for cell structures in suitable software. KW - Wood anatomy KW - Cell structures KW - Confocal laser scanning microscopy KW - CLSM KW - Dendrochronology KW - Surface preparation Y1 - 2013 U6 - https://doi.org/10.1016/j.dendro.2012.09.002 SN - 1125-7865 VL - 31 IS - 2 SP - 140 EP - 145 PB - Elsevier CY - Jena ER - TY - JOUR A1 - Tischer, Ute T1 - Manifestus error? Wrong Citation and literary Communication (on Gel. 15.6) JF - Mnemosyne : a journal of classical studies Y1 - 2013 SN - 0026-7074 VL - 66 IS - 3 SP - 411 EP - 432 PB - Brill CY - Leiden ER - TY - JOUR A1 - Conradt, Tobias A1 - Wechsung, F. A1 - Bronstert, Axel T1 - Three perceptions of the evapotranspiration landscape comparing spatial patterns from a distributed hydrological model, remotely sensed surface temperatures, and sub-basin water balances JF - Hydrology and earth system sciences : HESS N2 - A problem encountered by many distributed hydrological modelling studies is high simulation errors at interior gauges when the model is only globally calibrated at the outlet. We simulated river runoff in the Elbe River basin in central Europe (148 268 km(2)) with the semi-distributed eco-hydrological model SWIM (Soil and Water Integrated Model). While global parameter optimisation led to Nash-Sutcliffe efficiencies of 0.9 at the main outlet gauge, comparisons with measured runoff series at interior points revealed large deviations. Therefore, we compared three different strategies for deriving sub-basin evapotranspiration: (1) modelled by SWIM without any spatial calibration, (2) derived from remotely sensed surface temperatures, and (3) calculated from long-term precipitation and discharge data. The results show certain consistencies between the modelled and the remote sensing based evapotranspiration rates, but there seems to be no correlation between remote sensing and water balance based estimations. Subsequent analyses for single sub-basins identify amongst others input weather data and systematic error amplification in inter-gauge discharge calculations as sources of uncertainty. The results encourage careful utilisation of different data sources for enhancements in distributed hydrological modelling. Y1 - 2013 U6 - https://doi.org/10.5194/hess-17-2947-2013 SN - 1027-5606 VL - 17 IS - 7 SP - 2947 EP - 2966 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Sommer, Michael A1 - Jochheim, H. A1 - Höhn, Axel A1 - Breuer, Jörn A1 - Zagorski, Z. A1 - Busse, J. A1 - Barkusky, Dietmar A1 - Meier, K. A1 - Puppe, D. A1 - Wanner, Manfred A1 - Kaczorek, Danuta T1 - Si cycling in a forest biogeosystem - the importance of transient state biogenic Si pools JF - Biogeosciences N2 - The relevance of biological Si cycling for dissolved silica (DSi) export from terrestrial biogeosystems is still in debate. Even in systems showing a high content of weatherable minerals, like Cambisols on volcanic tuff, biogenic Si (BSi) might contribute > 50% to DSi (Gerard et al., 2008). However, the number of biogeosystem studies is rather limited for generalized conclusions. To cover one end of controlling factors on DSi, i.e., weatherable minerals content, we studied a forested site with absolute quartz dominance (> 95 %). Here we hypothesise minimal effects of chemical weathering of silicates on DSi. During a four year observation period (05/2007-04/2011), we quantified (i) internal and external Si fluxes of a temperate-humid biogeosystem (beech, 120 yr) by BIOME-BGC (version ZALF), (ii) related Si budgets, and (iii) Si pools in soil and beech, chemically as well as by SEM-EDX. For the first time two compartments of biogenic Si in soils were analysed, i.e., phytogenic and zoogenic Si pool (testate amoebae). We quantified an average Si plant uptake of 35 kg Si ha(-1) yr(-1) - most of which is recycled to the soil by litterfall - and calculated an annual biosilicification from idiosomic testate amoebae of 17 kg Si ha(-1). The comparatively high DSi concentrations (6 mg L-1) and DSi exports (12 kg Si ha(-1) yr(-1)) could not be explained by chemical weathering of feldspars or quartz dissolution. Instead, dissolution of a relictic, phytogenic Si pool seems to be the main process for the DSi observed. We identified canopy closure accompanied by a disappearance of grasses as well as the selective extraction of pine trees 30 yr ago as the most probable control for the phenomena observed. From our results we concluded the biogeosystem to be in a transient state in terms of Si cycling. Y1 - 2013 U6 - https://doi.org/10.5194/bg-10-4991-2013 SN - 1726-4170 VL - 10 IS - 7 SP - 4991 EP - 5007 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Solly, Emily A1 - Schöning, Ingo A1 - Boch, Steffen A1 - Mueller, J. A1 - Socher, S. A. A1 - Trumbore, S. E. A1 - Schrumpf, M. T1 - Mean age of carbon in fine roots from temperate forests and grasslands with different management JF - Biogeosciences N2 - Fine roots are the most dynamic portion of a plant's root system and a major source of soil organic matter. By altering plant species diversity and composition, soil conditions and nutrient availability, and consequently belowground allocation and dynamics of root carbon (C) inputs, land-use and management changes may influence organic C storage in terrestrial ecosystems. In three German regions, we measured fine root radiocarbon (C-14) content to estimate the mean time since C in root tissues was fixed from the atmosphere in 54 grassland and forest plots with different management and soil conditions. Although root biomass was on average greater in grasslands 5.1 +/- 0.8 g (mean +/- SE, n = 27) than in forests 3.1 +/- 0.5 g (n = 27) (p < 0.05), the mean age of C in fine roots in forests averaged 11.3 +/- 1.8 yr and was older and more variable compared to grasslands 1.7 +/- 0.4 yr (p < 0.001). We further found that management affects the mean age of fine root C in temperate grasslands mediated by changes in plant species diversity and composition. Fine root mean C age is positively correlated with plant diversity (r = 0.65) and with the number of perennial species (r = 0.77). Fine root mean C age in grasslands was also affected by study region with averages of 0.7 +/- 0.1 yr (n= 9) on mostly organic soils in northern Germany and of 1.8 +/- 0.3 yr (n = 9) and 2.6 +/- 0.3 (n = 9) in central and southern Germany (p < 0.05). This was probably due to differences in soil nutrient contents and soil moisture conditions between study regions, which affected plant species diversity and the presence of perennial species. Our results indicate more long-lived roots or internal redistribution of C in perennial species and suggest linkages between fine root C age and management in grasslands. These findings improve our ability to predict and model belowground C fluxes across broader spatial scales. Y1 - 2013 U6 - https://doi.org/10.5194/bg-10-4833-2013 SN - 1726-4170 VL - 10 IS - 7 SP - 4833 EP - 4843 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Thete, Aniket A1 - Rojas, Oscar A1 - Neumeyer, David A1 - Koetz, Joachim A1 - Dujardin, Erik T1 - Ionic liquid-assisted morphosynthesis of gold nanorods using polyethyleneimine-capped seeds JF - RSC Advances N2 - Seed-mediated gold nanorods with tunable lengths are prepared using new polyethyleneimine-capped gold nanoparticles synthesized in ionic liquid. The effect of polyethyleneimine and ionic liquid during nanorod growth is investigated and shows a marked effect on their final aspect ratio. Y1 - 2013 U6 - https://doi.org/10.1039/c3ra22112a SN - 2046-2069 VL - 3 IS - 34 SP - 14294 EP - 14298 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Sultanow, Eldar A1 - Weber, Edzard T1 - Pharmataxigraphie Model of a Hybrid System of RFID Technology and optical Methods JF - Die pharmazeutische Industrie Y1 - 2013 SN - 0031-711X VL - 75 IS - 7 SP - 1197 EP - + PB - Editio-Cantor-Verl. für Medizin und Naturwiss. CY - Aulendorf ER - TY - JOUR A1 - Pattyn, Frank A1 - Perichon, Laura A1 - Durand, Gael A1 - Favier, Lionel A1 - Gagliardini, Olivier A1 - Hindmarsh, Richard C. A. A1 - Zwinger, Thomas A1 - Albrecht, Torsten A1 - Cornford, Stephen A1 - Docquier, David A1 - Furst, Johannes J. A1 - Goldberg, Daniel A1 - Gudmundsson, Gudmundur Hilmar A1 - Humbert, Angelika A1 - Huetten, Moritz A1 - Huybrechts, Philippe A1 - Jouvet, Guillaume A1 - Kleiner, Thomas A1 - Larour, Eric A1 - Martin, Daniel A1 - Morlighem, Mathieu A1 - Payne, Anthony J. A1 - Pollard, David A1 - Rueckamp, Martin A1 - Rybak, Oleg A1 - Seroussi, Helene A1 - Thoma, Malte A1 - Wilkens, Nina T1 - Grounding-line migration in plan-view marine ice-sheet models: results of the ice2sea MISMIP3d intercomparison JF - Journal of glaciology N2 - Predictions of marine ice-sheet behaviour require models able to simulate grounding-line migration. We present results of an intercomparison experiment for plan-view marine ice-sheet models. Verification is effected by comparison with approximate analytical solutions for flux across the grounding line using simplified geometrical configurations (no lateral variations, no buttressing effects from lateral drag). Perturbation experiments specifying spatial variation in basal sliding parameters permitted the evolution of curved grounding lines, generating buttressing effects. The experiments showed regions of compression and extensional flow across the grounding line, thereby invalidating the boundary layer theory. Steady-state grounding-line positions were found to be dependent on the level of physical model approximation. Resolving grounding lines requires inclusion of membrane stresses, a sufficiently small grid size (<500 m), or subgrid interpolation of the grounding line. The latter still requires nominal grid sizes of <5 km. For larger grid spacings, appropriate parameterizations for ice flux may be imposed at the grounding line, but the short-time transient behaviour is then incorrect and different from models that do not incorporate grounding-line parameterizations. The numerical error associated with predicting grounding-line motion can be reduced significantly below the errors associated with parameter ignorance and uncertainties in future scenarios. Y1 - 2013 U6 - https://doi.org/10.3189/2013JoG12J129 SN - 0022-1430 VL - 59 IS - 215 SP - 410 EP - 422 PB - International Glaciological Society CY - Cambridge ER - TY - JOUR A1 - Schleussner, Carl-Friedrich A1 - Feulner, G. T1 - A volcanically triggered regime shift in the subpolar North Atlantic Ocean as a possible origin of the Little Ice Age JF - Climate of the past : an interactive open access journal of the European Geosciences Union N2 - Among the climatological events of the last millennium, the Northern Hemisphere Medieval Climate Anomaly succeeded by the Little Ice Age are of exceptional importance. The origin of these regional climate anomalies remains a subject of debate and besides external influences like solar and volcanic activity, internal dynamics of the climate system might have also played a dominant role. Here, we present transient last millennium simulations of the fully coupled model of intermediate complexity Climber 3a forced with stochastically reconstructed wind-stress fields. Our results indicate that short-lived volcanic eruptions might have triggered a cascade of sea ice ocean feedbacks in the North Atlantic, ultimately leading to a persistent regime shift in the ocean circulation. We find that an increase in the Nordic Sea sea-ice extent on decadal timescales as a consequence of major volcanic eruptions in our model leads to a spin-up of the subpolar gyre and a weakened Atlantic meridional overturning circulation, eventually causing a persistent, basin-wide cooling. These results highlight the importance of regional climate feedbacks such as a regime shift in the subpolar gyre circulation for understanding the dynamics of past and future climate. Y1 - 2013 U6 - https://doi.org/10.5194/cp-9-1321-2013 SN - 1814-9324 SN - 1814-9332 VL - 9 IS - 3 SP - 1321 EP - 1330 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Girstmair, Hannah A1 - Saffert, Paul A1 - Rode, Sascha A1 - Czech, Andreas A1 - Holland, Gudrun A1 - Bannert, Norbert A1 - Ignatova, Zoya T1 - Depletion of Cognate Charged Transfer RNA Causes Translational Frameshifting within the Expanded CAG Stretch in Huntingtin JF - Cell reports N2 - Huntington disease (HD), a dominantly inherited neurodegenerative disorder caused by the expansion of a CAG-encoded polyglutamine (polyQ) repeat in huntingtin (Htt), displays a highly heterogeneous etiopathology and disease onset. Here, we show that the translation of expanded CAG repeats in mutant Htt exon 1 leads to a depletion of charged glutaminyl-transfer RNA (tRNA) Gln-CUG that pairs exclusively to the CAG codon. This results in translational frameshifting and the generation of various transframe-encoded species that differently modulate the conformational switch to nucleate fibrillization of the parental polyQ protein. Intriguingly, the frameshifting frequency varies strongly among different cell lines and is higher in cells with intrinsically lower concentrations of tRNA Gln-CUG. The concentration of tRNA Gln-CUG also differs among different brain areas in the mouse. We propose that translational frameshifting may act as a significant disease modifier that contributes to the cell-selective neurotoxicity and disease course heterogeneity of HD on both cellular and individual levels. Y1 - 2013 U6 - https://doi.org/10.1016/j.celrep.2012.12.019 SN - 2211-1247 VL - 3 IS - 1 SP - 148 EP - 159 PB - Cell Press CY - Cambridge ER - TY - JOUR A1 - Schiefele, Ulrich A1 - Schaffner, Ellen T1 - Reading motivation of Sixth-Grade Elementary School Students - results from an interview study JF - Psychologie in Erziehung und Unterricht : Zeitschrift für Forschung und Praxis N2 - Based on research by Wigfield and Guthrie (1997), Moller and Bonerad (2007) as well as Schaffner and Schiefele (2007) have developed questionnaires to assess students' reading motivation. The goal of the present study was to examine whether these instruments coincide with students' subjective views of their own reading motivation. In order to clarify this question, we conducted interviews with 26 elementary school students and applied content analysis to examine the interview protocols. Although the results support some of the theoretically postulated components, they suggest that questionnaire measures have neglected some important aspects of reading motivation (e. g., reading to regulate one's feelings, reading to relax). Finally, consequences for the revision of reading motivation questionnaires were discussed. KW - Reading motivation KW - interview method KW - elementary school Y1 - 2013 U6 - https://doi.org/10.2378/peu2013.art17d SN - 0342-183X VL - 60 IS - 3 SP - 214 EP - 233 PB - Reinhardt CY - München ER - TY - JOUR A1 - Dumont, Hanna A1 - Neumann, Marko A1 - Nagy, Gabriel A1 - Becker, Michael A1 - Rose, Norman A1 - Trautwein, Ulrich T1 - Class composition Effects in non-academic lower secondary school tracks in the state of Baden-Württemberg JF - Psychologie in Erziehung und Unterricht : Zeitschrift für Forschung und Praxis N2 - The study investigates the effects of classroom composition (average ability, achievement, and socio-economic background, proportion of immigrant students) on the development in mathematics achievement, and reading literacy from grade 5 to 6. The study draws on a sample of N=1892 students in vocational track schools (Hauptschule) and intermediate track schools (Realschule) in Baden-Wuerttemberg, Germany. After controlling for school type, and between-school differences in student intake characteristics, none of the compositional characteristics showed a statistically significant effect on achievement development. School track was associated with the development of reading literacy even after controlling for individual differences; however, this relationship lost its statistical significance after the composition of the student body was additionally taken into account. KW - Academic achievement KW - tracking KW - reading comprehension KW - mathematics KW - composition effects Y1 - 2013 U6 - https://doi.org/10.2378/peu2013.art16d SN - 0342-183X VL - 60 IS - 3 SP - 198 EP - 213 PB - Reinhardt CY - München ER - TY - JOUR A1 - Dumont, Hanna A1 - Neumann, Marko A1 - Maaz, Kai A1 - Trautwein, Ulrich T1 - The effect of student body composition on academic achievement International and National Evidence JF - Psychologie in Erziehung und Unterricht : Zeitschrift für Forschung und Praxis N2 - This paper reviews empirical evidence on the effect of the composition of a student body on academic achievement of students. After defining the term composition effect, methodological aspects regarding the study of composition effects are considered. International and national evidence for the composition of a student body with respect to students' abilities, social, and ethnic background is then presented. Whereas international studies find evidence for social, ethnic, and achievement composition variables, national studies reveal that mean achievement level of a school or class is the most important composition variable in Germany. However, this effect is confounded with school track and social composition, which itself exerts a small incremental effect. Ethnic composition, however, does not seem to play an important role. The paper closes with a presentation of the underlying processes of composition effects and a discussion on how the composition of a student body is considered in school governance practices. KW - Composition effects KW - academic achievement KW - tracking Y1 - 2013 U6 - https://doi.org/10.2378/peu2013.art14d SN - 0342-183X VL - 60 IS - 3 SP - 163 EP - 183 PB - Reinhardt CY - München ER - TY - JOUR A1 - Heinken, Thilo A1 - Weber, Ewald T1 - Consequences of habitat fragmentation for plant species do we know enough? JF - Perspectives in plant ecology, evolution and systematics N2 - Habitat fragmentation is one of the most important causes for the decline of plant species. However, plants differing in phylogeny, habitat requirements and biology are likely to respond differently to habitat fragmentation. We ask whether case studies on the effects of habitat fragmentation conducted so far allow generalizations about its effects on the fitness and genetic diversity of populations of endangered plant species. We compared the characteristics of plant species endangered in Germany whose sensitivity to habitat fragmentation had been studied with those of the endangered species that had not been studied. We found strong discrepancies between the two groups with regard to their taxonomy and traits relevant to their sensitivity to habitat fragmentation. Monocots, graminoids, clonal, abiotically pollinated and self compatible species were underrepresented among the studied species, and most study species were from a few habitat types, in particular grasslands. We conclude that our current knowledge of the effects of habitat fragmentation on plant populations is not sufficient to provide widely applicable guidelines for species management. The selection of species studied so far has been biased toward species from certain habitats and species exhibiting traits that probably make them vulnerable to habitat fragmentation. Future studies should include community-wide approaches in different habitats, e.g. re-visitation studies in which the species pool is assessed at different time intervals, and population-biological studies of species from a wide range of habitats, and of different life forms and growth strategies. A more representative picture of the effects of habitat fragmentation would allow a better assessment of threats and more specific recommendations for optimally managing populations of endangered plants. KW - CSR-strategies KW - Naturally rare species KW - Plant conservation KW - Recently rare species KW - Species traits KW - Taxonomic position Y1 - 2013 U6 - https://doi.org/10.1016/j.ppees.2013.05.003 SN - 1433-8319 VL - 15 IS - 4 SP - 205 EP - 216 PB - Elsevier CY - Jena ER - TY - JOUR A1 - Mondal, Suvendu Sekhar A1 - Bhunia, Asamanjoy A1 - Baburin, Igor A. A1 - Jäger, Christian A1 - Kelling, Alexandra A1 - Schilde, Uwe A1 - Seifert, Gotthard A1 - Janiak, Christoph A1 - Holdt, Hans-Jürgen T1 - Gate effects in a hexagonal zinc-imidazolate-4-amide-5-imidate framework with flexible methoxy substituents and CO2 selectivity JF - Chemical communications N2 - A new imidazolate-4-amide-5-imidate based MOF, IFP-7, is generated, having flexible methoxy groups, which act as molecular gates for guest molecules. This allows highly selective CO2 sorption over N-2 and CH4 gases. Y1 - 2013 U6 - https://doi.org/10.1039/c3cc42156b SN - 1359-7345 VL - 49 IS - 69 SP - 7599 EP - 7601 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Ozsayin, Erman A1 - Ciner, T. Attila A1 - Rojay, F. Bora A1 - Dirik, R. Kadir A1 - Melnick, Daniel A1 - Fernandez-Blanco, David A1 - Bertotti, Giovanni A1 - Schildgen, Taylor F. A1 - Garcin, Yannick A1 - Strecker, Manfred A1 - Sudo, Masafumi T1 - Plio-Quaternary extensional tectonics of the Central Anatolian Plateau a case study from the Tuz Golu Basin, Turkey JF - Turkish journal of earth sciences = Türk yerbilimleri dergisi N2 - The Tuz Golu Basin is the largest sedimentary depression located at the center of the Central Anatolian Plateau, an extensive, low-relief region with elevations of ca. 1 km located between the Pontide and Tauride mountains. Presently, the basin morphology and sedimentation processes are mainly controlled by the extensional Tuz Golu Fault Zone in the east and the transtensional Inonu-Eskisehir Fault System in the west. The purpose of this study is to contribute to the understanding of the Plio-Quaternary deformation history and to refine the timing of the latest extensional phase of the Tuz Golu Basin. Field observations, kinematic analyses, interpretations of seismic reflection lines, and Ar-40/Ar-39 dating of a key ignimbrite layer suggest that a regional phase of NNW-SSE to NE-SW contraction ended by 6.81 +/- 0.24 Ma and was followed by N-S to NE-SW extension during the Pliocene-Quaternary periods. Based on sedimentological and chronostratigraphic markers, the average vertical displacement rates over the past 5 or 3 Ma with respect to the central part of Tuz Golu Lake are 0.03 to 0.05 mm/year for the fault system at the western flank of the basin and 0.08 to 0.13 mm/year at the eastern flank. Paleo-shorelines of the Tuz Golu Lake, vestiges of higher lake levels related to Quaternary climate change, are important strain markers and were formed during Last Glacial Maximum conditions as indicated by a radiocarbon age of 21.8 +/- 0.4 ka BP obtained from a stromatolitic crust. Geomorphic observations and deformed lacustrine shorelines suggest that the main strand of the Tuz Golu Fault Zone straddling the foothills of the Sereflikochisar-Aksaray range has not been active during the Holocene. Instead, deformation appears to have migrated towards the interior of the basin along an offshore fault that runs immediately west of Sereflikochisar Peninsula. This basinward migration of deformation is probably associated with various processes acting at the lithospheric scale, such as plateau uplift and/or microplate extrusion. KW - Central Anatolia KW - Tuz Golu Basin KW - orogenic plateau evolution KW - extensional tectonics KW - kinematic analysis KW - lake shoreline Y1 - 2013 U6 - https://doi.org/10.3906/yer-1210-5 SN - 1300-0985 VL - 22 IS - 5 SP - 691 EP - 714 PB - Tübitak CY - Ankara ER - TY - JOUR A1 - Reich, Sebastian T1 - A nonparametric ensemble transform method for bayesian inference JF - SIAM journal on scientific computing N2 - Many applications, such as intermittent data assimilation, lead to a recursive application of Bayesian inference within a Monte Carlo context. Popular data assimilation algorithms include sequential Monte Carlo methods and ensemble Kalman filters (EnKFs). These methods differ in the way Bayesian inference is implemented. Sequential Monte Carlo methods rely on importance sampling combined with a resampling step, while EnKFs utilize a linear transformation of Monte Carlo samples based on the classic Kalman filter. While EnKFs have proven to be quite robust even for small ensemble sizes, they are not consistent since their derivation relies on a linear regression ansatz. In this paper, we propose another transform method, which does not rely on any a priori assumptions on the underlying prior and posterior distributions. The new method is based on solving an optimal transportation problem for discrete random variables. KW - Bayesian inference KW - Monte Carlo method KW - sequential data assimilation KW - linear programming KW - resampling Y1 - 2013 U6 - https://doi.org/10.1137/130907367 SN - 1064-8275 VL - 35 IS - 4 SP - A2013 EP - A2024 PB - Society for Industrial and Applied Mathematics CY - Philadelphia ER - TY - JOUR A1 - Itoh, N. A1 - Marwan, Norbert T1 - An extended singular spectrum transformation (SST) for the investigation of Kenyan precipitation data JF - Nonlinear processes in geophysics N2 - In this paper a change-point detection method is proposed by extending the singular spectrum transformation (SST) developed as one of the capabilities of singular spectrum analysis (SSA). The method uncovers change points related with trends and periodicities. The potential of the proposed method is demonstrated by analysing simple model time series including linear functions and sine functions as well as real world data (precipitation data in Kenya). A statistical test of the results is proposed based on a Monte Carlo simulation with surrogate methods. As a result, the successful estimation of change points as inherent properties in the representative time series of both trend and harmonics is shown. With regards to the application, we find change points in the precipitation data of Kenyan towns (Nakuru, Naivasha, Narok, and Kisumu) which coincide with the variability of the Indian Ocean Dipole (IOD) suggesting its impact of extreme climate in East Africa. Y1 - 2013 U6 - https://doi.org/10.5194/npg-20-467-2013 SN - 1023-5809 VL - 20 IS - 4 SP - 467 EP - 481 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Zibulski, Romy A1 - Herzschuh, Ulrike A1 - Pestryakova, Luidmila Agafyevna A1 - Wolter, Juliane A1 - Mueller, S. A1 - Schilling, N. A1 - Wetterich, Sebastian A1 - Schirrmeister, Lutz A1 - Tian, Fang T1 - River flooding as a driver of polygon dynamics: modern vegetation data and a millennial peat record from the Anabar River lowlands (Arctic Siberia) JF - Biogeosciences N2 - The spatial and temporal variability of a low-centred polygon on the eastern floodplain area of the lower Anabar River (72.070 degrees N, 113.921 degrees E; northern Yakutia, Siberia) has been investigated using a multi-method approach. The present-day vegetation in each square metre was analysed, revealing a community of Larix, shrubby Betula, and Salix on the polygon rim, a dominance of Carex and Andromeda polifolia in the rim-to-pond transition zone, and a predominantly monospecific Scorpidium scorpioides coverage within the pond. The total organic carbon (TOC) content, TOC/TN (total nitrogen) ratio, grain size, vascular plant macrofossils, moss remains, diatoms, and pollen were analysed for two vertical sections and a sediment core from a transect across the polygon. Radiocarbon dating indicates that the formation of the polygon started at least 1500 yr ago; the general positions of the pond and rim have not changed since that time. Two types of pond vegetation were identified, indicating two contrasting development stages of the polygon. The first was a well-established moss association, dominated by submerged or floating Scorpidium scorpioides and/or Drepanocladus spp. and overgrown by epiphytic diatoms such as Tabellaria flocculosa and Eunotia taxa. This stage coincides temporally with a period in which the polygon was only drained by lateral subsurface water flow, as indicated by mixed grain sizes. A different moss association occurred during times of repeated river flooding (indicated by homogeneous medium-grained sand that probably accumulated during the annual spring snowmelt), characterized by an abundance of Meesia triquetra and a dominance of benthic diatoms (e. g. Navicula vulpina), indicative of a relatively high pH and a high tolerance of disturbance. A comparison of the local polygon vegetation (inferred from moss and macrofossil spectra) with the regional vegetation (inferred from pollen spectra) indicated that the moss association with Scorpidium scorpioides became established during relatively favourable climatic conditions, while the association dominated by Meesia triquetra occurred during periods of harsh climatic conditions. Our study revealed a strong riverine influence (in addition to climatic influences) on polygon development and the type of peat accumulated. Y1 - 2013 U6 - https://doi.org/10.5194/bg-10-5703-2013 SN - 1726-4170 VL - 10 IS - 8 SP - 5703 EP - 5728 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Schrade, Lisa A1 - Scheffler, Christiane T1 - Assessing the applicability of the digital laser rangefinder GLM Professional (R) Bosch 250 VF for anthropometric field studies JF - Journal of biological and clinical anthropology : Anthropologischer Anzeiger ; Mitteilungsorgan der Gesellschaft für Anthropologie N2 - The digital laser rangefinder GLM Professional (R) BOSCH 250 VF was tested as a modified preproduction model with regard to its applicability of quantifying humans' height. The aim of this investigation was to determine and evaluate the instrument's precision, as well as its manageability within anthropometric field studies. Data collected by the digital laser rangefinder did not show a significant difference to data of control by an anthropometer. Furthermore, more than 96% of the difference values are located within area of agreement. Nevertheless, the GLM Professional (R) is a highly sensitive instrument and mean SD within threefold data acquisition is twice as high as SD resulting from data collection by an anthropometer. However, due to the minimal percentage differences within data acquisition and compared to the standard method, the GLM Professional (R) is proved to be a reliable instrument and to be highly applicable for anthropometric field studies. Furthermore, due to its excellent manageability and compact size, the GLM Professional (R) shows a very good applicability even for less trained anthropometrists and thus ameliorates the possibilities of collecting reliable data within anthropometric field studies. KW - anthropometric field studies KW - height KW - measuring instrument KW - digital laser range finder Y1 - 2013 U6 - https://doi.org/10.1127/0003-5548/2013/0223 SN - 0003-5548 VL - 70 IS - 2 SP - 137 EP - 145 PB - Schweizerbart CY - Stuttgart ER - TY - JOUR A1 - Inal, Sahika A1 - Koelsch, Jonas D. A1 - Chiappisi, Leonardo A1 - Janietz, Dietmar A1 - Gradzielski, Michael A1 - Laschewsky, André A1 - Neher, Dieter T1 - Structure-related differences in the temperature-regulated fluorescence response of LCST type polymers JF - Journal of materials chemistry : C, Materials for optical and electronic devices N2 - We demonstrate new fluorophore-labelled materials based on acrylamide and on oligo(ethylene glycol) (OEG) bearing thermoresponsive polymers for sensing purposes and investigate their thermally induced solubility transitions. It is found that the emission properties of the polarity-sensitive (solvatochromic) naphthalimide derivative attached to three different thermoresponsive polymers are highly specific to the exact chemical structure of the macromolecule. While the dye emits very weakly below the LCST when incorporated into poly(N-isopropylacrylamide) (pNIPAm) or into a polyacrylate backbone bearing only short OEG side chains, it is strongly emissive in polymethacrylates with longer OEG side chains. Heating of the aqueous solutions above their cloud point provokes an abrupt increase of the fluorescence intensity of the labelled pNIPAm, whereas the emission properties of the dye are rather unaffected as OEG-based polyacrylates and methacrylates undergo phase transition. Correlated with laser light scattering studies, these findings are ascribed to the different degrees of pre-aggregation of the chains at low temperatures and to the extent of dehydration that the phase transition evokes. It is concluded that although the temperature-triggered changes in the macroscopic absorption characteristics, related to large-scale alterations of the polymer chain conformation and aggregation, are well detectable and similar for these LCST-type polymers, the micro-environment provided to the dye within each polymer network differs substantially. Considering sensing applications, this finding is of great importance since the temperature-regulated fluorescence response of the polymer depends more on the macromolecular architecture than the type of reporter fluorophore. Y1 - 2013 U6 - https://doi.org/10.1039/c3tc31304b SN - 2050-7526 VL - 1 IS - 40 SP - 6603 EP - 6612 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Men, Yongjun A1 - Siebenbürger, Miriam A1 - Qiu, Xunlin A1 - Antonietti, Markus A1 - Yuan, Jiayin T1 - Low fractions of ionic liquid or poly(ionic liquid) can activate polysaccharide biomass into shaped, flexible and fire-retardant porous carbons JF - Journal of materials chemistry : A, Materials for energy and sustainability N2 - Sugar-based molecules and polysaccharide biomass can be turned into porous functional carbonaceous products at comparably low temperatures of 400 degrees C under a nitrogen atmosphere in the presence of an ionic liquid (IL) or a poly(ionic liquid) (PIL). The IL and PIL act as "activation agents" with own structural contribution, and effectively promote the conversion and pore generation in the biomaterials even at a rather low doping ratio (7 wt%). In addition, this "induced carbonization" and pore forming phenomenon enables the preservation of the biotemplate shape to the highest extent and was employed to fabricate shaped porous carbonaceous materials from carbohydrate-based biotemplates, exemplified here with cellulose filter membranes, coffee filter paper and natural cotton. These carbonized hybrids exhibit comparably good mechanical properties, such as bendability of membranes or shape recovery of foams. Moreover, the nitrogen atoms incorporated in the final products from the IL/PIL precursors further improve the oxidation stability in the fire-retardant tests. Y1 - 2013 U6 - https://doi.org/10.1039/c3ta12302b SN - 2050-7488 VL - 1 IS - 38 SP - 11887 EP - 11893 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Gross, Martina A1 - Warschburger, Petra T1 - Chronic abdominal pain psychosocial strain and treatment-associated changes in coping JF - Verhaltenstherapie N2 - Background: Chronic abdominal pain (CAP) in childhood is a commonly occurring condition and shows a high stability. Psychosocial dysfunctioning of children, such as increased stress experience, is a burden for children and parents and complicates clinical management. Additional comorbid disorders may develop. To minimize the onset of such disorders, treatment at an early stage and taking psychosocial aspects into consideration is strongly recommended. Through this approach, the cognitive-behavioral, child-centered group program 'Stop the pain with Happy-Pingu' was developed, applied, and subsequently evaluated. What is the psychosocial situation of the affected children? Can the cognitive-behavioral group program be applied to improve psychosocial limitations? Method: The cognitive-behavioral group program comprises 6 weekly sessions for children and 1 single meeting for parents. In a randomized controlled study, the program was evaluated with 29 children aged between 6 and 12 years. The evaluation was based on a comparison between the intervention group (IG) and the waiting list control group (WLC), measured at 3 measurement points: T1 (pre), T2 (post), and T3 (3-month follow-up). Results: Emotional problems in particular can emerge in children with CAP. The program was well received, with a high level of participation through to completion. The results demonstrate that children participating in the IG experience significant stress reduction and improved psychosocial functioning compared to children participating in the WLC. The effect sizes range from medium to high. Conclusions: Drawing upon the above findings, multimodal cognitive-behavioral techniques appear to be suitable to successfully treat children with CAP. However, further controlled studies are required to identify the specific elements of the training that are most effective in reducing pain. KW - Cognitive-behavioral therapy KW - Children KW - Abdominal pain KW - Psychosocial functioning KW - Coping Y1 - 2013 U6 - https://doi.org/10.1159/000351215 SN - 1016-6262 VL - 23 IS - 2 SP - 80 EP - 89 PB - Karger CY - Basel ER - TY - JOUR A1 - Nishikawa, Ken-Ichi A1 - Hardee, P. A1 - Zhang, B. A1 - Dutan, I. A1 - Medvedev, M. A1 - Choi, E. J. A1 - Min, K. W. A1 - Niemiec, J. A1 - Mizuno, Y. A1 - Nordlund, Ake A1 - Frederiksen, Jacob Trier A1 - Sol, H. A1 - Pohl, Martin A1 - Hartmann, D. H. T1 - Magnetic field generation in a jet-sheath plasma via the kinetic Kelvin-Helmholtz instability JF - Annales geophysicae N2 - We have investigated the generation of magnetic fields associated with velocity shear between an unmagnetized relativistic jet and an unmagnetized sheath plasma. We have examined the strong magnetic fields generated by kinetic shear (Kelvin-Helmholtz) instabilities. Compared to the previous studies using counter-streaming performed by Alves et al. (2012), the structure of the kinetic Kelvin-Helmholtz instability (KKHI) of our jet-sheath configuration is slightly different, even for the global evolution of the strong transverse magnetic field. In our simulations the major components of growing modes are the electric field E-z, perpendicular to the flow boundary, and the magnetic field B-y, transverse to the flow direction. After the B-y component is excited, an induced electric field E-x, parallel to the flow direction, becomes significant. However, other field components remain small. We find that the structure and growth rate of KKHI with mass ratios m(i)/m(e) = 1836 and m(i)/m(e) = 20 are similar. In our simulations in the nonlinear stage is not as clear as in counter-streaming cases. The growth rate for a mildly-relativistic jet case (gamma(j) = 1.5) is larger than for a relativistic jet case (gamma(j) = 15). KW - Solar physics KW - astrophysics KW - astronomy (Energetic particles) Y1 - 2013 U6 - https://doi.org/10.5194/angeo-31-1535-2013 SN - 0992-7689 VL - 31 IS - 9 SP - 1535 EP - 1541 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Peitsch, Helmut T1 - Rosa Luxembourg in 20th century german literature JF - Zeitschrift für Religions- und Geistesgeschichte Y1 - 2013 SN - 0044-3441 VL - 65 IS - 2 SP - 152 EP - 172 PB - Brill CY - Leiden ER - TY - JOUR A1 - Brechenmacher, Thomas T1 - The apostolic see and totalitarian ideologies the 1937 march-encyclicals in their inner context JF - Historisches Jahrbuch Y1 - 2013 SN - 0018-2621 VL - 133 IS - 2 SP - 342 EP - 364 PB - Alber CY - Freiburg Breisgau ER - TY - JOUR A1 - Huber, Robert A1 - Rigling, Andreas A1 - Bebi, Peter A1 - Brand, Fridolin Simon A1 - Briner, Simon A1 - Buttler, Alexandre A1 - Elkin, Che A1 - Gillet, Francois A1 - Gret-Regamey, Adrienne A1 - Hirschi, Christian A1 - Lischke, Heike A1 - Scholz, Roland Werner A1 - Seidl, Roman A1 - Spiegelberger, Thomas A1 - Walz, Ariane A1 - Zimmermann, Willi A1 - Bugmann, Harald T1 - Sustainable land use in Mountain Regions under global change synthesis across scales and disciplines JF - Ecology and society : a journal of integrative science for resilience and sustainability N2 - Mountain regions provide essential ecosystem goods and services (EGS) for both mountain dwellers and people living outside these areas. Global change endangers the capacity of mountain ecosystems to provide key services. The Mountland project focused on three case study regions in the Swiss Alps and aimed to propose land-use practices and alternative policy solutions to ensure the provision of key EGS under climate and land-use changes. We summarized and synthesized the results of the project and provide insights into the ecological, socioeconomic, and political processes relevant for analyzing global change impacts on a European mountain region. In Mountland, an integrative approach was applied, combining methods from economics and the political and natural sciences to analyze ecosystem functioning from a holistic human-environment system perspective. In general, surveys, experiments, and model results revealed that climate and socioeconomic changes are likely to increase the vulnerability of the EGS analyzed. We regard the following key characteristics of coupled human-environment systems as central to our case study areas in mountain regions: thresholds, heterogeneity, trade-offs, and feedback. Our results suggest that the institutional framework should be strengthened in a way that better addresses these characteristics, allowing for (1) more integrative approaches, (2) a more network-oriented management and steering of political processes that integrate local stakeholders, and (3) enhanced capacity building to decrease the identified vulnerability as central elements in the policy process. Further, to maintain and support the future provision of EGS in mountain regions, policy making should also focus on project-oriented, cross-sectoral policies and spatial planning as a coordination instrument for land use in general. KW - adaptive management KW - climate change KW - ecosystem services KW - experiments KW - interdisciplinary research KW - land-use change KW - modeling KW - transdisciplinary research Y1 - 2013 U6 - https://doi.org/10.5751/ES-05499-180336 SN - 1708-3087 VL - 18 IS - 3 PB - Resilience Alliance CY - Wolfville ER - TY - JOUR A1 - Cherstvy, Andrey G. A1 - Metzler, Ralf T1 - Population splitting, trapping, and non-ergodicity in heterogeneous diffusion processes JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - We consider diffusion processes with a spatially varying diffusivity giving rise to anomalous diffusion. Such heterogeneous diffusion processes are analysed for the cases of exponential, power-law, and logarithmic dependencies of the diffusion coefficient on the particle position. Combining analytical approaches with stochastic simulations, we show that the functional form of the space-dependent diffusion coefficient and the initial conditions of the diffusing particles are vital for their statistical and ergodic properties. In all three cases a weak ergodicity breaking between the time and ensemble averaged mean squared displacements is observed. We also demonstrate a population splitting of the time averaged traces into fast and slow diffusers for the case of exponential variation of the diffusivity as well as a particle trapping in the case of the logarithmic diffusivity. Our analysis is complemented by the quantitative study of the space coverage, the diffusive spreading of the probability density, as well as the survival probability. Y1 - 2013 U6 - https://doi.org/10.1039/c3cp53056f SN - 1463-9076 SN - 1463-9084 VL - 15 IS - 46 SP - 20220 EP - 20235 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Inal, Sahika A1 - Kölsch, Jonas D. A1 - Sellrie, Frank A1 - Schenk, Jörg A. A1 - Wischerhoff, Erik A1 - Laschewsky, André A1 - Neher, Dieter T1 - A water soluble fluorescent polymer as a dual colour sensor for temperature and a specific protein JF - Journal of materials chemistry : B, Materials for biology and medicine N2 - We present two thermoresponsive water soluble copolymers prepared via free radical statistical copolymerization of N-isopropylacrylamide (NIPAm) and of oligo(ethylene glycol) methacrylates (OEGMAs), respectively, with a solvatochromic 7-(diethylamino)-3-carboxy-coumarin (DEAC)-functionalized monomer. In aqueous solutions, the NIPAm-based copolymer exhibits characteristic changes in its fluorescence profile in response to a change in solution temperature as well as to the presence of a specific protein, namely an anti-DEAC antibody. This polymer emits only weakly at low temperatures, but exhibits a marked fluorescence enhancement accompanied by a change in its emission colour when heated above its cloud point. Such drastic changes in the fluorescence and absorbance spectra are observed also upon injection of the anti-DEAC antibody, attributed to the specific binding of the antibody to DEAC moieties. Importantly, protein binding occurs exclusively when the polymer is in the well hydrated state below the cloud point, enabling a temperature control on the molecular recognition event. On the other hand, heating of the polymer-antibody complexes releases a fraction of the bound antibody. In the presence of the DEAC-functionalized monomer in this mixture, the released antibody competitively binds to the monomer and the antibody-free chains of the polymer undergo a more effective collapse and inter-aggregation. In contrast, the emission properties of the OEGMA-based analogous copolymer are rather insensitive to the thermally induced phase transition or to antibody binding. These opposite behaviours underline the need for a carefully tailored molecular design of responsive polymers aimed at specific applications, such as biosensing. Y1 - 2013 U6 - https://doi.org/10.1039/c3tb21245a SN - 2050-750X SN - 2050-7518 VL - 1 IS - 46 SP - 6373 EP - 6381 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Mondal, Suvendu Sekhar A1 - Dey, Subarna A1 - Baburin, Igor A. A1 - Kelling, Alexandra A1 - Schilde, Uwe A1 - Seifert, Gotthard A1 - Janiak, Christoph A1 - Holdt, Hans-Jürgen T1 - Syntheses of two imidazolate-4-amide-5-imidate linker-based hexagonal metal-organic frameworks with flexible ethoxy substituent JF - CrystEngComm N2 - A rare example of in situ linker generation with the formation of soft porous Zn- and Co-MOFs (IFP-9 and -10, respectively) is reported. The flexible ethoxy groups of IFP-9 and -10 protrude into the 1D hexagonal channels. The gas-sorption behavior of both materials for H-2, CO2 and CH4 showed wide hysteretic isotherms, typical for MOFs having a flexible substituent which can give rise to a gate effect. Y1 - 2013 U6 - https://doi.org/10.1039/c3ce41632a SN - 1466-8033 VL - 15 IS - 45 SP - 9394 EP - 9399 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Laubrock, Jochen A1 - Cajar, Anke A1 - Engbert, Ralf T1 - Control of fixation duration during scene viewing by interaction of foveal and peripheral processing JF - Journal of vision N2 - Processing in our visual system is functionally segregated, with the fovea specialized in processing fine detail (high spatial frequencies) for object identification, and the periphery in processing coarse information (low frequencies) for spatial orienting and saccade target selection. Here we investigate the consequences of this functional segregation for the control of fixation durations during scene viewing. Using gaze-contingent displays, we applied high-pass or low-pass filters to either the central or the peripheral visual field and compared eye-movement patterns with an unfiltered control condition. In contrast with predictions from functional segregation, fixation durations were unaffected when the critical information for vision was strongly attenuated (foveal low-pass and peripheral high-pass filtering); fixation durations increased, however, when useful information was left mostly intact by the filter (foveal high-pass and peripheral low-pass filtering). These patterns of results are difficult to explain under the assumption that fixation durations are controlled by foveal processing difficulty. As an alternative explanation, we developed the hypothesis that the interaction of foveal and peripheral processing controls fixation duration. To investigate the viability of this explanation, we implemented a computational model with two compartments, approximating spatial aspects of processing by foveal and peripheral activations that change according to a small set of dynamical rules. The model reproduced distributions of fixation durations from all experimental conditions by variation of few parameters that were affected by specific filtering conditions. KW - scene perception KW - spatial frequencies KW - fixation durations KW - computational modeling Y1 - 2013 U6 - https://doi.org/10.1167/13.12.11 SN - 1534-7362 VL - 13 IS - 12 PB - Association for Research in Vision and Opthalmology CY - Rockville ER - TY - JOUR A1 - Barthelme, Simon A1 - Trukenbrod, Hans Arne A1 - Engbert, Ralf A1 - Wichmann, Felix A. T1 - Modeling fixation locations using spatial point processes JF - Journal of vision N2 - Whenever eye movements are measured, a central part of the analysis has to do with where subjects fixate and why they fixated where they fixated. To a first approximation, a set of fixations can be viewed as a set of points in space; this implies that fixations are spatial data and that the analysis of fixation locations can be beneficially thought of as a spatial statistics problem. We argue that thinking of fixation locations as arising from point processes is a very fruitful framework for eye-movement data, helping turn qualitative questions into quantitative ones. We provide a tutorial introduction to some of the main ideas of the field of spatial statistics, focusing especially on spatial Poisson processes. We show how point processes help relate image properties to fixation locations. In particular we show how point processes naturally express the idea that image features' predictability for fixations may vary from one image to another. We review other methods of analysis used in the literature, show how they relate to point process theory, and argue that thinking in terms of point processes substantially extends the range of analyses that can be performed and clarify their interpretation. KW - eye movements KW - fixation locations KW - saliency KW - modeling KW - point process KW - spatial statistics Y1 - 2013 U6 - https://doi.org/10.1167/13.12.1 SN - 1534-7362 VL - 13 IS - 12 PB - Association for Research in Vision and Opthalmology CY - Rockville ER - TY - JOUR A1 - Barbosa Pfannes, Eva Katharina A1 - Anielski, Alexander A1 - Gerhardt, Matthias A1 - Beta, Carsten T1 - Intracellular photoactivation of caged cGMP induces myosin II and actin responses in motile cells JF - Integrative biology N2 - Cyclic GMP (cGMP) is a ubiquitous second messenger in eukaryotic cells. It is assumed to regulate the association of myosin II with the cytoskeleton of motile cells. When cells of the social amoeba Dictyostelium discoideum are exposed to chemoattractants or to increased osmotic stress, intracellular cGMP levels rise, preceding the accumulation of myosin II in the cell cortex. To directly investigate the impact of intracellular cGMP on cytoskeletal dynamics in a living cell, we released cGMP inside the cell by laser-induced photo-cleavage of a caged precursor. With this approach, we could directly show in a live cell experiment that an increase in intracellular cGMP indeed induces myosin II to accumulate in the cortex. Unexpectedly, we observed for the first time that also the amount of filamentous actin in the cell cortex increases upon a rise in the cGMP concentration, independently of cAMP receptor activation and signaling. We discuss our results in the light of recent work on the cGMP signaling pathway and suggest possible links between cGMP signaling and the actin system. Y1 - 2013 U6 - https://doi.org/10.1039/c3ib40109j SN - 1757-9694 SN - 1757-9708 VL - 5 IS - 12 SP - 1456 EP - 1463 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Pfurtscheller, Clemens A1 - Thieken, Annegret T1 - The price of safety costs for mitigating and coping with Alpine hazards JF - Natural hazards and earth system sciences N2 - Due to limited public budgets and the need to economize, the analysis of costs of hazard mitigation and emergency management of natural hazards becomes increasingly important for public natural hazard and risk management. In recent years there has been a growing body of literature on the estimation of losses which supported to help to determine benefits of measures in terms of prevented losses. On the contrary, the costs of mitigation are hardly addressed. This paper thus aims to shed some light on expenses for mitigation and emergency services. For this, we analysed the annual costs of mitigation efforts in four regions/countries of the Alpine Arc: Bavaria (Germany), Tyrol (Austria), South Tyrol (Italy) and Switzerland. On the basis of PPP values (purchasing power parities), annual expenses on public safety ranged from EUR 44 per capita in the Free State of Bavaria to EUR 216 in the Autonomous Province of South Tyrol. To analyse the (variable) costs for emergency services in case of an event, we used detailed data from the 2005 floods in the Federal State of Tyrol (Austria) as well as aggregated data from the 2002 floods in Germany. The analysis revealed that multi-hazards, the occurrence and intermixture of different natural hazard processes, contribute to increasing emergency costs. Based on these findings, research gaps and recommendations for costing Alpine natural hazards are discussed. Y1 - 2013 U6 - https://doi.org/10.5194/nhess-13-2619-2013 SN - 1561-8633 VL - 13 IS - 10 SP - 2619 EP - 2637 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Cammerer, H. A1 - Thieken, Annegret A1 - Lammel, J. T1 - Adaptability and transferability of flood loss functions in residential areas JF - Natural hazards and earth system sciences N2 - Flood loss modeling is an important component within flood risk assessments. Traditionally, stage-damage functions are used for the estimation of direct monetary damage to buildings. Although it is known that such functions are governed by large uncertainties, they are commonly applied - even in different geographical regions - without further validation, mainly due to the lack of real damage data. Until now, little research has been done to investigate the applicability and transferability of such damage models to other regions. In this study, the last severe flood event in the Austrian Lech Valley in 2005 was simulated to test the performance of various damage functions from different geographical regions in Central Europe for the residential sector. In addition to common stage-damage curves, new functions were derived from empirical flood loss data collected in the aftermath of recent flood events in neighboring Germany. Furthermore, a multi-parameter flood loss model for the residential sector was adapted to the study area and also evaluated with official damage data. The analysis reveals that flood loss functions derived from related and more similar regions perform considerably better than those from more heterogeneous data sets of different regions and flood events. While former loss functions estimate the observed damage well, the latter overestimate the reported loss clearly. To illustrate the effect of model choice on the resulting uncertainty of damage estimates, the current flood risk for residential areas was calculated. In the case of extreme events like the 300 yr flood, for example, the range of losses to residential buildings between the highest and the lowest estimates amounts to a factor of 18, in contrast to properly validated models with a factor of 2.3. Even if the risk analysis is only performed for residential areas, our results reveal evidently that a carefree model transfer in other geographical regions might be critical. Therefore, we conclude that loss models should at least be selected or derived from related regions with similar flood and building characteristics, as far as no model validation is possible. To further increase the general reliability of flood loss assessment in the future, more loss data and more comprehensive loss data for model development and validation are needed. Y1 - 2013 U6 - https://doi.org/10.5194/nhess-13-3063-2013 SN - 1561-8633 VL - 13 IS - 11 SP - 3063 EP - 3081 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Feger, Martina A1 - Fajol, Abul A1 - Lebedeva, Aleksandra A1 - Meissner, Adrian A1 - Michael, Diana A1 - Völkl, Jakob A1 - Alesutan, Ioana A1 - Schleicher, Erwin A1 - Reichetzeder, Christoph A1 - Hocher, Berthold A1 - Qadri, Syed M. A1 - Lang, Florian T1 - Effect of Carbon Monoxide Donor CORM-2 on Vitamin D-3 Metabolism JF - Kidney & blood pressure research : official organ of the Gesellschaft für Nephrologie N2 - Background/Aims: Carbon monoxide (CO) interferes with cytochrome-dependent cellular functions and acts as gaseous transmitter. CO is released from CO-releasing molecules (CORM) including tricarbonyl-dichlororuthenium (II) dimer (CORM-2), molecules considered for the treatment of several disorders including vascular dysfunction, inflammation, tissue ischemia and organ rejection. Cytochrome P450-sensitive function include formation of 1,25-dihydroxyvitamin D-3 (1,25(OH)(2)D-3) by renal 25-hydroxyvitamin D-3 1-alpha-hydroxylase (Cyp27b1). The enzyme is regulated by PTH, FGF23 and klotho. 1,25(OH)(2)D-3 regulates Ca2+ and phosphate transport as well as klotho expression. The present study explored, whether CORM-2 influences 1,25(OH)(2)D-3 formation and klotho expression. Methods: Mice were treated with intravenous CORM-2 (20 mg/kg body weight). Plasma 1,25(OH)(2)D-3 and FGF23 concentrations were determined by ELISA, phosphate, calcium and creatinine concentrations by colorimetric methods, transcript levels by quantitative RT-PCR and protein expression by western blotting. Fgf23 mRNA transcript levels were further determined in rat osteosarcoma UMR106 cells without or with prior treatment for 24 hours with 20 mu M CORM-2. Results: CORM-2 injection within 24 hours significantly increased FGF23 plasma levels and decreased 1,25(OH)(2)D-3 plasma levels, renal Cyp27b1 gene expression as well as renal klotho protein abundance and transcript levels. Moreover, treatment of UMR106 cells with CORM-2 significantly increased Fgf23 transcript levels. Conclusion: CO-releasing molecule CORM-2 enhances FGF23 expression and release and decreases klotho expression and 1,25(OH)(2)D-3 synthesis. KW - CORM-2 KW - 1,25-Dihydroxyvitamin D-3 KW - Klotho KW - FGF23 KW - Phosphate KW - Calcium Y1 - 2013 U6 - https://doi.org/10.1159/000355730 SN - 1420-4096 SN - 1423-0143 VL - 37 IS - 4-5 SP - 496 EP - 505 PB - Karger CY - Basel ER - TY - JOUR A1 - Hocher, Berthold A1 - Oberthür, Dominik A1 - Slowinski, Torsten A1 - Querfeld, Uwe A1 - Schäfer, Franz A1 - Doyon, Anke A1 - Tepel, Martin A1 - Roth, Heinz J. A1 - Grön, Hans J. A1 - Reichetzeder, Christoph A1 - Betzel, Christian A1 - Armbruster, Franz Paul T1 - Modeling of Oxidized PTH (oxPTH) and Non-oxidized PTH (n-oxPTH) Receptor Binding and Relationship of Oxidized to Non-Oxidized PTH in Children with Chronic Renal Failure, Adult Patients on Hemodialysis and Kidney Transplant Recipients JF - Kidney & blood pressure research : official organ of the Gesellschaft für Nephrologie N2 - Background: The biological properties of oxidized and non-oxidized PTH are substantially different. Oxidized PTH (oxPTH) loses its PTH receptor-stimulating properties, whereas non-oxidized PTH (n-oxPTH) is a full agonist of the receptor. This was described in more than 20 well published studies in the 1970(s) and 80(s). However, PTH oxidation has been ignored during the development of PTH assays for clinical use so far. Even the nowadays used third generation assay systems do not consider oxidation of PTH. We recently developed an assay to differentiate between oxPTH and n-oxPTH. In the current study we established normal values for this assay system. Furthermore, we compare the ratio of oxPTH to n-oxPTH in different population with chronic renal failure: 620 children with renal failure stage 2-4 of the 4C study, 342 adult patients on dialysis, and 602 kidney transplant recipients. In addition, we performed modeling of the interaction of either oxPTH or n-oxPTH with the PTH receptor using biophysical structure approaches. Results: The children had the highest mean as well as maximum n-oxPTH concentrations as compared to adult patients (both patients on dialysis as well as kidney transplant recipients). The relationship between oxPTH and n-oxPTH of individual patients varied substantially in all three populations with renal impairment. The analysis of n-oxPTH in 89 healthy control subjects revealed that n-oxPTH concentrations in patient with renal failure were higher as compared to healthy adult controls (2.25-fold in children with renal failure, 1.53-fold in adult patients on dialysis, and 1.56-fold in kidney transplant recipients, respectively). Computer assisted biophysical structure modeling demonstrated, however, minor sterical- and/or electrostatic changes in oxPTH and n-oxPTH. This indicated that PTH oxidation may induce refolding of PTH and hence alters PTH-PTH receptor interaction via oxidation induced three-dimensional structure alteration of PTH. Conclusion: A huge proportion of circulating PTH measured by current state-of-the-art assay systems is oxidized and thus not biologically active. The relationship between oxPTH and n-oxPTH of individual patients varied substantially. Non-oxidized PTH concentrations are 1.5 - 2.25 fold higher in patients with renal failure as compared to health controls. Measurements of n-oxPTH may reflect the hormone status more precise. The iPTH measures describes most likely oxidative stress in patients with renal failure rather than the PTH hormone status. This, however, needs to be demonstrated in further clinical studies. KW - n-oxPTH KW - Chronic Renal Failure KW - Kidney Transplantation KW - Hemodialysis KW - Oxidation KW - PTH KW - Chronic Renal Failure in Children Y1 - 2013 U6 - https://doi.org/10.1159/000350149 SN - 1420-4096 SN - 1423-0143 VL - 37 IS - 4-5 SP - 240 EP - 251 PB - Karger CY - Basel ER - TY - JOUR A1 - McCurdy, Kate A1 - Kentner, Gerrit A1 - Vasishth, Shravan T1 - Implicit prosody and contextual bias in silent reading JF - Journal of Eye Movement Research N2 - Eye-movement research on implicit prosody has found effects of lexical stress on syntactic ambiguity resolution, suggesting that metrical well-formedness constraints interact with syntactic category assignment. Building on these findings, the present eyetracking study investigates whether contextual bias can modulate the effects of metrical structure on syntactic ambiguity resolution in silent reading. Contextual bias and potential stress-clash in the ambiguous region were crossed in a 2 x 2 design. Participants read biased context sentences followed by temporarily ambiguous test sentences. In the three-word ambiguous region, main effects of lexical stress were dominant, while early effects of context were absent. Potential stress clash yielded a significant increase in first-pass regressions and re-reading probability across the three words. In the disambiguating region, the disambiguating word itself showed increased processing difficulty (lower skipping and increased re-reading probability) when the disambiguation engendered a stress clash configuration, while the word immediately following showed main effects of context in those same measures. Taken together, effects of lexical stress upon eye movements were swift and pervasive across first-pass and second-pass measures, while effects of context were relatively delayed. These results indicate a strong role for implicit meter in guiding parsing, one that appears insensitive to higher-level constraints. Our findings are problematic for two classes of models, the two-stage garden-path model and the constraint-based competition-integration model, but can be explained by a variation on the two-stage model, the unrestricted race model. KW - silent prosody KW - stress-clash KW - implicit meter KW - context KW - reanalysis KW - gardenpath model KW - competition-integration model KW - unrestricted race model KW - re-reading probability KW - skipping rate Y1 - 2013 SN - 1995-8692 VL - 6 IS - 2 PB - International Group for Eye Movement Research CY - Bern ER - TY - JOUR A1 - Burgold, Julia A1 - Rolfes, Manfred T1 - Of voyeuristic safari tours and responsible tourism with educational value observing moral communication in slum and township tourism in Cape Town and Mumbai JF - Die Erde : journal of the Geographical Society of Berlin ; Zeitschrift der Gesellschaft für Erdkunde zu Berlin N2 - Sightseeing in the poorest quarters of southern hemisphere cities has been observed occurring in Cape Town, Rio de Janeiro, Mumbai and many other cities. The increasing global interest in touring poor urban environments is accompanied by a strong morally charged debate; so far, this debate has not been critically addressed. This article avoids asking if slum tourism is good or bad, but instead seeks a second-order observation, i.e. to investigate under what conditions the social praxis of slum tourism is considered as good or bad, by processing information on esteem or dis-esteem among tourists and tour providers. Special attention is given to any relation between morality and place, and the thesis posited is that the moral charging of slum tourism is dependent on the presence of specific preconceived notions of slums and poverty. This shall be clarified by means of references to two empirical case studies carried out in (1) Cape Town in 2007 and 2008 and (2) Mumbai in 2009. KW - Slum tourism KW - township tourism KW - morality KW - place Y1 - 2013 SN - 0013-9998 VL - 144 IS - 2 SP - 161 EP - 174 PB - Gesellschaft für Erdkunde CY - Berlin ER - TY - JOUR A1 - Wang, Jing A1 - Fritzsch, Claire A1 - Bernarding, Johannes A1 - Krause, Thomas A1 - Mauritz, Karl-Heinz A1 - Brunetti, Maddalena A1 - Dohle, Christian T1 - Cerebral activation evoked by the mirror illusion of the hand in stroke patients compared to normal subjects JF - Neurorehabilitation : an interdisciplinary journal N2 - BACKGROUND: Mirror therapy (MT) was found to improve motor function after stroke, but its neural mechanisms remain unclear, especially in single stroke patients. OBJECTIVES: The following imaging study was designed to compare brain activation patterns evoked by the mirror illusion in single stroke patients with normal subjects. METHODS: Fifteen normal volunteers and five stroke patients with severe arm paresis were recruited. Cerebral activations during movement mirroring by means of a video chain were recorded with functional magnetic resonance imaging (fMRI). Single-subject analysis was performed using SPM 8. RESULTS: For normal subjects, ten and thirteen subjects displayed lateralized cerebral activations evoked by the mirror illusion while moving their right and left hand respectively. The magnitude of this effect in the precuneus contralateral to the seen hand was not dependent on movement speed or subjective experience. Negative correlation of activation strength with age was found for the right hand only. The activation pattern in stroke patients is comparable to that of normal subjects and present in four out of five patients. CONCLUSIONS: In summary, the mirror illusion can elicit cerebral activation contralateral to the perceived hand in the majority of single normal subjects, but not in all of them. This is similar even in stroke patients with severe hemiparesis. KW - Movement KW - mirror illusion KW - imaging KW - mirror therapy KW - stroke Y1 - 2013 U6 - https://doi.org/10.3233/NRE-130999 SN - 1053-8135 SN - 1878-6448 VL - 33 IS - 4 SP - 593 EP - 603 PB - IOS Press CY - Amsterdam ER - TY - JOUR A1 - Zimmermann, B. A1 - Zimmermann, Alexander A1 - Scheckenbach, H. L. A1 - Schmid, T. A1 - Hall, Jefferson. S. A1 - van Breugel, Michiel T1 - Changes in rainfall interception along a secondary forest succession gradient in lowland Panama JF - Hydrology and earth system sciences : HESS N2 - Secondary forests are rapidly expanding in tropical regions. Yet, despite the importance of understanding the hydrological consequences of land-cover dynamics, the relationship between forest succession and canopy interception is poorly understood. This lack of knowledge is unfortunate because rainfall interception plays an important role in regional water cycles and needs to be quantified for many modeling purposes. To help close this knowledge gap, we designed a throughfall monitoring study along a secondary succession gradient in a tropical forest region of Panama. The investigated gradient comprised 20 forest patches 3 to 130 yr old. We sampled each patch with a minimum of 20 funnel-type throughfall collectors over a continuous 2month period that had nearly 900 mm of rain. During the same period, we acquired forest inventory data and derived several forest structural attributes. We then applied simple and multiple regression models (Bayesian model averaging, BMA) and identified those vegetation parameters that had the strongest influence on the variation of canopy interception. Our analyses yielded three main findings. First, canopy interception changed rapidly during forest succession. After only a decade, throughfall volumes approached levels that are typical for mature forests. Second, a parsimonious (simple linear regression) model based on the ratio of the basal area of small stems to the total basal area outperformed more complex multivariate models (BMA approach). Third, based on complementary forest inventory data, we show that the influence of young secondary forests on interception in realworld fragmented landscapes might be detectable only in regions with a substantial fraction of young forests. Our re-sults suggest that where entire catchments undergo forest regrowth, initial stages of succession may be associated with a substantial decrease of streamflow generation. Our results further highlight the need to study hydrological processes in all forest succession stages, including early ones. Y1 - 2013 U6 - https://doi.org/10.5194/hess-17-4659-2013 SN - 1027-5606 SN - 1607-7938 VL - 17 IS - 11 SP - 4659 EP - 4670 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Zaourar, N. A1 - Hamoudi, M. A1 - Mandea, M. A1 - Balasis, G. A1 - Holschneider, Matthias T1 - Wavelet-based multiscale analysis of geomagnetic disturbance JF - EARTH PLANETS AND SPACE N2 - The dynamics of external contributions to the geomagnetic field is investigated by applying time-frequency methods to magnetic observatory data. Fractal models and multiscale analysis enable obtaining maximum quantitative information related to the short-term dynamics of the geomagnetic field activity. The stochastic properties of the horizontal component of the transient external field are determined by searching for scaling laws in the power spectra. The spectrum fits a power law with a scaling exponent beta, a typical characteristic of self-affine time-series. Local variations in the power-law exponent are investigated by applying wavelet analysis to the same time-series. These analyses highlight the self-affine properties of geomagnetic perturbations and their persistence. Moreover, they show that the main phases of sudden storm disturbances are uniquely characterized by a scaling exponent varying between 1 and 3, possibly related to the energy contained in the external field. These new findings suggest the existence of a long-range dependence, the scaling exponent being an efficient indicator of geomagnetic activity and singularity detection. These results show that by using magnetogram regularity to reflect the magnetosphere activity, a theoretical analysis of the external geomagnetic field based on local power-law exponents is possible. KW - Geomagnetic field KW - magnetosphere KW - geomagnetic storm KW - multiscale analysis KW - spectral exponent Y1 - 2013 U6 - https://doi.org/10.5047/eps.2013.05.001 SN - 1343-8832 SN - 1880-5981 VL - 65 IS - 12 SP - 1525 EP - 1540 PB - TERRA SCIENTIFIC PUBL CO CY - TOKYO ER - TY - JOUR A1 - Lu, Yong-Ping A1 - Zeng, De-Ying A1 - Chen, You-Peng A1 - Liang, Xu-Jing A1 - Xu, Jie-Ping A1 - Huang, Si-Min A1 - Lai, Zhi-Wei A1 - Wen, Wang-Rong A1 - von Websky, Karoline A1 - Hocher, Berthold T1 - Low birth weight is associated with lower respiratory tract infections in children with hand, foot, and mouth disease JF - Clinical laboratory : the peer reviewed journal for clinical laboratories and laboratories related to blood transfusion N2 - Background: Low birth weight (LBW) might be a risk factor for acquiring lower respiratory tract infections (LRTIs) associated with disease related complications in early childhood. HFMD, a frequent viral infection in southern China, is a leading cause of lower respiratory tract infections in children. We analyzed whether LBW is a risk factor for children with HFMD to develop lower respiratory tract infections. Methods: A total of 298 children with HFMD, admitted to a hospital in Qingyuan city, Guangdong province, were recruited. Demographic data and clinical parameters such as serum glucose level and inflammatory markers including peripheral white blood cell count, serum C-reactive protein, and erythrocyte sedimentation rate were routinely collected on admission. Birth weight data were derived from birth records. Results: Mean birth weight (BW) was 167 g lower in patients with HFMD and LRTIs as compared to patients with solely HFMD (p = 0.022) and the frequency of birth weight below the tenth percentile was significantly higher in patients with HFMD and LRTIs (p = 0.002). Conclusions: The results of the study show that low birth weight is associated with a higher incidence of lower respiratory tract infections in young children with HFMD. KW - hand KW - foot and mouth disease (HFMD) KW - low birth weight (LBW) KW - lower respiratory tract infections (LRTIs) KW - pneumonia KW - children Y1 - 2013 U6 - https://doi.org/10.7754/Clin.Lab.2012.120725 SN - 1433-6510 VL - 59 IS - 9-10 SP - 985 EP - 992 PB - Clin Lab Publ., Verl. Klinisches Labor CY - Heidelberg ER - TY - JOUR A1 - May, Felix A1 - Giladi, Itamar A1 - Ristow, Michael A1 - Ziv, Yaron A1 - Jeltsch, Florian T1 - Plant functional traits and community assembly along interacting gradients of productivity and fragmentation JF - Perspectives in plant ecology, evolution and systematics N2 - Quantifying the association of plant functional traits to environmental gradients is a promising approach for understanding and projecting community responses to land use and climatic changes. Although habitat fragmentation and climate are expected to affect plant communities interactively, there is a lack of empirical studies addressing trait associations to fragmentation in different climatic regimes. In this study, we analyse data on the key functional traits: specific leaf area (SLA), plant height, seed mass and seed number. First, we assess the evidence for the community assembly mechanisms habitat filtering and competition at different spatial scales, using several null-models and a comprehensive set of community-level trait convergence and divergence indices. Second, we analyse the association of community-mean traits with patch area and connectivity along a south-north productivity gradient. We found clear evidence for trait convergence due to habitat filtering. In contrast, the evidence for trait divergence due to competition fundamentally depended on the null-model used. When the null-model controlled for habitat filtering, there was only evidence for trait divergence at the smallest sampling scale (0.25 m x 0.25 m). All traits varied significantly along the S-N productivity gradient. While plant height and SLA were consistently associated with fragmentation, the association of seed mass and seed number with fragmentation changed along the S-N gradient. Our findings indicate trait convergence due to drought stress in the arid sites and due to higher productivity in the mesic sites. The association of plant traits to fragmentation is likely driven by increased colonization ability in small and/or isolated patches (plant height, seed number) or increased persistence ability in isolated patches (seed mass). Our study provides the first empirical test of trait associations with fragmentation along a productivity gradient. We conclude that it is crucial to study the interactive effects of different ecological drivers on plant functional traits. KW - Connectivity KW - Drought-stress KW - Habitat filtering KW - Limiting similarity KW - Null models KW - Plant height KW - Seed mass KW - Seed number KW - Specific leaf area (SLA) Y1 - 2013 U6 - https://doi.org/10.1016/j.ppees.2013.08.002 SN - 1433-8319 VL - 15 IS - 6 SP - 304 EP - 318 PB - Elsevier CY - Jena ER - TY - JOUR A1 - Menon, Arathy A1 - Levermann, Anders A1 - Schewe, Jacob A1 - Lehmann, J. A1 - Frieler, Katja T1 - Consistent increase in Indian monsoon rainfall and its variability across CMIP-5 models JF - Earth system dynamics N2 - The possibility of an impact of global warming on the Indian monsoon is of critical importance for the large population of this region. Future projections within the Coupled Model Intercomparison Project Phase 3 (CMIP-3) showed a wide range of trends with varying magnitude and sign across models. Here the Indian summer monsoon rainfall is evaluated in 20 CMIP-5 models for the period 1850 to 2100. In the new generation of climate models, a consistent increase in seasonal mean rainfall during the summer monsoon periods arises. All models simulate stronger seasonal mean rainfall in the future compared to the historic period under the strongest warming scenario RCP-8.5. Increase in seasonal mean rainfall is the largest for the RCP-8.5 scenario compared to other RCPs. Most of the models show a northward shift in monsoon circulation by the end of the 21st century compared to the historic period under the RCP-8.5 scenario. The interannual variability of the Indian monsoon rainfall also shows a consistent positive trend under unabated global warming. Since both the long-term increase in monsoon rainfall as well as the increase in interannual variability in the future is robust across a wide range of models, some confidence can be attributed to these projected trends. Y1 - 2013 U6 - https://doi.org/10.5194/esd-4-287-2013 SN - 2190-4979 SN - 2190-4987 VL - 4 IS - 2 SP - 287 EP - 300 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Van Bel, Michiel A1 - Proost, Sebastian A1 - Van Neste, Christophe A1 - Deforce, Dieter A1 - Van de Peer, Yves A1 - Vandepoele, Klaas T1 - TRAPID - an efficient online tool for the functional and comparative analysis of de novo RNA-Seq transcriptomes JF - Genome biology : biology for the post-genomic era N2 - Transcriptome analysis through next-generation sequencing technologies allows the generation of detailed gene catalogs for non-model species, at the cost of new challenges with regards to computational requirements and bioinformatics expertise. Here, we present TRAPID, an online tool for the fast and efficient processing of assembled RNA-Seq transcriptome data, developed to mitigate these challenges. TRAPID offers high-throughput open reading frame detection, frameshift correction and includes a functional, comparative and phylogenetic toolbox, making use of 175 reference proteomes. Benchmarking and comparison against state-of-the-art transcript analysis tools reveals the efficiency and unique features of the TRAPID system. Y1 - 2013 U6 - https://doi.org/10.1186/gb-2013-14-12-r134 SN - 1465-6906 SN - 1474-760X VL - 14 IS - 12 PB - BioMed Central CY - London ER - TY - JOUR A1 - Rüder, Constantin A1 - Sauter, Tilman A1 - Kratz, Karl A1 - Haase, Tobias A1 - Peter, Jan A1 - Jung, Friedrich A1 - Lendlein, Andreas A1 - Zohlnhöfer, Dietlind T1 - Influence of fibre diameter and orientation of electrospun copolyetheresterurethanes on smooth muscle and endothelial cell behaviour JF - Clinical hemorheology and microcirculation : blood flow and vessels N2 - Polymers exhibiting cell-selective effects represent an extensive research field with high relevance for biomedical applications e.g. in the cardiovascular field supporting re-endothelialization while suppressing smooth muscle cell overgrowth. Such an endothelial cell-selective effect could be recently demonstrated for a copolyetheresterurethane (PDC) containing biodegradable poly(p-dioxanone) and poly(epsilon-caprolactone) segments, which selectively enhanced the adhesion of human umbilical vein endothelial cells (HUVEC) while suppressing the attachment of smooth muscle cells (SMC). In this study we investigated the influence of the fibre orientation (random and aligned) and fibre diameter (2 mu m and 500 nm) of electrospun PDC scaffolds on the adhesion, proliferation and apoptosis of HUVEC and SMC. Adhesion, viability and proliferation of HUVEC was diminished when the fibre diameter was reduced to a submicron scale, while the orientation of the microfibres did only slightly influence the cellular behaviour. In contrast, a submicron fibre diameter improved SMC viability. In conclusion, PDC scaffolds with micron-sized single fibres could be promising candidate materials for cell-selective stent coatings. KW - Endothelialization KW - drug eluting stent KW - degradable polymer KW - electrospinning KW - cell selectivity Y1 - 2013 U6 - https://doi.org/10.3233/CH-131787 SN - 1386-0291 SN - 1875-8622 VL - 55 IS - 4 SP - 513 EP - 522 PB - IOS Press CY - Amsterdam ER - TY - JOUR A1 - Drygala, Frank A1 - Werner, Ulrike A1 - Zoller, Hinrich T1 - Diet composition of the invasive raccoon dog (Nyctereutes procyonoides) and the native red fox (Vulpes vulpes) in north-east Germany JF - Hystrix : the Italian journal of mammalogy N2 - Invasive alien species pose a great threat to the integrity of natural communities by competition with and predation on native species. In Germany the invasive raccoon dog (Nyctereutes procyonoides) and the native red fox (Vulpes vulpes) occupy a similar ecological niche. Therefore, the aim of our study was to discover the extent of exploitative diet competition between these two generalist carnivores. Carcasses of red foxes (n=256) and raccoon dogs (n=253) were collected throughout Mecklenburg Western-Pomerania (north-east Germany) and stomachs contains were analysed. Frequency of occurrence and biomass share indicate that both canids are omnivorous and pursue opportunistic feeding strategies. Small mammals and edible plant material were the most important food resources for red foxes and raccoon dogs. Nonetheless, interspecies differences were recorded for edible plant material, small mammals and insects. While red foxes mostly feed on voles, raccoon dogs consumed mice and shrews as often as voles. Only raccoon dogs preyed on amphibians. There were no differences in carrion consumption, both species scavenged on wild boar and we found clear competition for carrion year-round. Moreover, there was evidence that two red foxes foraged on raccoon dogs and vice versa. The mean annual interspecies diet overlap index was relatively high. The diets determined for raccoon dogs and red foxes were quite similar and a similar food niche breadth was recorded. However, only minor competition is assumed to take place since differences in feeding habits do exist. KW - Nyctereutes procyonoides KW - Vulpes vulpes KW - invasive species KW - diet competition KW - feeding strategies Y1 - 2013 U6 - https://doi.org/10.4404/hystrix.-24.2-8867 SN - 0394-1914 SN - 1825-5272 VL - 24 IS - 2 SP - 190 EP - 194 PB - Associazione Teriologica Romana CY - Roma ER - TY - JOUR A1 - Mahler, B. A1 - Schneider, A. R. R. A1 - Di Giacomo, A. S. A1 - Di Giacomo, A. G. A1 - Reboreda, Juan C. A1 - Tiedemann, Ralph T1 - Microsatellite usefulness is independent of phylogenetic distance in Tyrant flycatchers (Aves: Tyrannidae) - a test using two globally threatened species JF - Genetics and molecular research N2 - Tyrant flycatchers (Aves: Tyrannidae) are endemic to the New World, and many species of this group are threatened or near-threatened at the global level. The aim of this study was to test the 18 microsatellite markers that have been published for other Tyrant flycatchers in the Strange-tailed Tyrant (Alectrurus risora) and the Sharp-tailed Tyrant (Culicivora caudacuta), two endemic species of southern South American grasslands that are classified as vulnerable. We also analyzed the usefulness of loci in relation to phylogenetic distance to the source species. Amplification success was high in both species (77 to 83%) and did not differ between the more closely and more distantly related species to the source species. Polymorphism success was also similar for both species, with 9 and 8 loci being polymorphic, respectively. An increased phylogenetic distance thus does not gradually lead to allelic or locus dropouts, implying that in Tyrant flycatchers, the published loci are useful independent of species relatedness. KW - Alectrurus risora KW - Culicivora caudacuta KW - Microsatellites KW - Tyrannidae Y1 - 2013 U6 - https://doi.org/10.4238/2013.August.12.12 SN - 1676-5680 VL - 12 IS - 3 SP - 2966 EP - 2972 PB - FUNPEC CY - Ribeirao Preto ER - TY - JOUR A1 - Debussche, Arnaud A1 - Hoegele, Michael A1 - Imkeller, Peter T1 - The source of stochastic models in conceptual climate dynamics JF - Lecture notes in mathematics : a collection of informal reports and seminars JF - Lecture Notes in Mathematics Y1 - 2013 SN - 978-3-319-00828-8; 978-3-319-00827-1 U6 - https://doi.org/10.1007/978-3-319-00828-8 SN - 0075-8434 VL - 2085 IS - 3 SP - 151 EP - 157 PB - Springer CY - Berlin ER - TY - JOUR A1 - Debussche, Arnaud A1 - Högele, Michael A1 - Imkeller, Peter T1 - Localization and metastability JF - Lecture notes in mathematics : a collection of informal reports and seminars JF - Lecture Notes in Mathematics N2 - In this chapter, equipped with our previously obtained knowledge of exit and transition times in the limit of small noise amplitude ??0 , we shall investigate the global asymptotic behavior of our jump diffusion process in the time scale in which transitions occur, i.e. in the scale given by ?0(?)=?(1?Bc?(0)),?,?>0 . It turns out that in this time scale, the switching of the diffusion between neighborhoods of the stable solutions ? ± can be well described by a Markov chain jumping back and forth between two states with a characteristic Q-matrix determined by the quantities ?((D±0)c)?(Bc?(0)) as jumping rates. Y1 - 2013 SN - 978-3-319-00828-8; 978-3-319-00827-1 U6 - https://doi.org/10.1007/978-3-319-00828-8_7 SN - 0075-8434 VL - 2085 SP - 131 EP - 149 PB - Springer CY - Berlin ER - TY - JOUR A1 - Debussche, Arnaud A1 - Hoegele, Michael A1 - Imkeller, Peter T1 - Asymptotic transition times JF - Lecture notes in mathematics : a collection of informal reports and seminars JF - Lecture Notes in Mathematics Y1 - 2013 SN - 978-3-319-00828-8; 978-3-319-00827-1 U6 - https://doi.org/10.1007/978-3-319-00828-8_6 SN - 0075-8434 VL - 2085 SP - 121 EP - 130 PB - Springer CY - Berlin ER - TY - JOUR A1 - Debussche, Arnaud A1 - Hoegele, Michael A1 - Imkeller, Peter T1 - Asymptotic exit times JF - Lecture notes in mathematics : a collection of informal reports and seminars JF - Lecture Notes in Mathematics Y1 - 2013 SN - 978-3-319-00828-8; 978-3-319-00827-1 U6 - https://doi.org/10.1007/978-3-319-00828-8_5 SN - 0075-8434 VL - 2085 SP - 87 EP - 120 PB - Springer CY - Berlin ER - TY - JOUR A1 - Debussche, Arnaud A1 - Hoegele, Michael A1 - Imkeller, Peter T1 - The small deviation of the small noise solution JF - Lecture notes in mathematics : a collection of informal reports and seminars JF - Lecture Notes in Mathematics Y1 - 2013 SN - 978-3-319-00828-8; 978-3-319-00827-1 U6 - https://doi.org/10.1007/978-3-319-00828-8_4 SN - 0075-8434 VL - 2085 SP - 69 EP - 85 PB - Springer CY - Berlin ER - TY - JOUR A1 - Debussche, Arnaud A1 - Högele, Michael A1 - Imkeller, Peter T1 - The stochastic chafee-infante equation JF - Lecture notes in mathematics : a collection of informal reports and seminars JF - Lecture Notes in Mathematics N2 - In this preparatory chapter, the tools of stochastic analysis needed for the investigation of the asymptotic behavior of the stochastic Chafee-Infante equation are provided. In the first place, this encompasses a recollection of basic facts about Lévy processes with values in Hilbert spaces. Playing the role of the additive noise processes perturbing the deterministic Chafee-Infante equation in the systems the stochastic dynamics of which will be our main interest, symmetric ?-stable Lévy processes are in the focus of our investigation (Sect. 3.1). Y1 - 2013 SN - 978-3-319-00828-8; 978-3-319-00827-1 U6 - https://doi.org/10.1007/978-3-319-00828-8_3 SN - 0075-8434 VL - 2085 SP - 45 EP - 68 PB - Springer CY - Berlin ER - TY - JOUR A1 - Debussche, Arnaud A1 - Högele, Michael A1 - Imkeller, Peter T1 - The Fine Dynamics of the Chafee-Infante Equation JF - Lecture notes in mathematics : a collection of informal reports and seminars JF - Lecture Notes in Mathematics N2 - In this chapter, we introduce the deterministic Chafee-Infante equation. This equation has been the subject of intense research and is very well understood now. We recall some properties of its longtime dynamics and in particular the structure of its attractor. We then define reduced domains of attraction that will be fundamental in our study and give a result describing precisely the time that a solution starting form a reduced domain of attraction needs to reach a stable equilibrium. This result is then proved using the detailed knowledge of the attractor and classical tools such as the stable and unstable manifolds in a neighborhood of an equilibrium. Y1 - 2013 SN - 978-3-319-00828-8; 978-3-319-00827-1 U6 - https://doi.org/10.1007/978-3-319-00828-8_2 SN - 0075-8434 VL - 2085 SP - 11 EP - 43 PB - Springer CY - Berlin ER - TY - JOUR A1 - Li, Jian A1 - Chen, You-Peng A1 - Wang, Zi-Neng A1 - Liu, Tie-Bin A1 - Chen, Dan A1 - Dong, Yun-Peng A1 - Hocher, Berthold T1 - A functional fetal HSD11B2[CA]n microsatellite polymorphism is associated with maternal serum cortisol concentrations in pregnant women JF - Kidney & blood pressure research : official organ of the Gesellschaft für Nephrologie N2 - Background/Aims: Cortisol plays an important role during pregnancy. It controls maternal glucose metabolism and fetal development. Cortisol metabolism is partially controlled by the 11b-HSD2. This enzyme is expressed in the kidney and human placenta. The activity of the enzyme is partially controlled by functional polymorphisms: the HSD11B2[CA]n microsatellite polymorphism. The impact of this functional gene polymorphism on cortisol metabolism and potential effects on the newborn's is unknown so far. Methods: In the current prospective birth cohort study in southern Asia, we analyzed the association of the HSD11B2[CA]n microsatellite polymorphisms in 187 mothers and their newborn's on maternal and newborn's serum cortisol concentrations. Results: Using multivariable regression analyses considering known confounding ( gestational age, newborn's gender, the labor uterine contraction states and the timing during the day of blood taking), we showed that the fetal HSD11B2[CA]n microsatellite polymorphisms in the first intron was related to maternal cortisol concentration ( R2=0.26, B=96.27, p=0.007), whereas as the newborn's cortisol concentrations were independent of fetal and maternal HSD11B2[CA] n microsatellite polymorphism. Conclusions: Our study showed for the first time that the fetal HSD11B2[CA]n microsatellite polymorphism of the HSD11B2 gene in healthy uncomplicated human pregnancy is associated with maternal cortisol concentration. This indicates that fetal genes controlling cortisol metabolism may affect maternal cortisol concentration and hence physiology in healthy pregnant women. KW - Pregnancy KW - Placenta KW - Cortisol vertical bar metabolism KW - 11 beta-hydroxysteroid dehydrogenase 2 KW - HSD11B2[CA]n polymorphism Y1 - 2013 U6 - https://doi.org/10.1159/000355761 SN - 1420-4096 SN - 1423-0143 VL - 38 IS - 1 SP - 132 EP - 141 PB - Karger CY - Basel ER - TY - JOUR A1 - Warditz, Vladislava Maria T1 - The linguistic Reception of the French Novel in Russia the Phenomenon of the Argot in Hugo's Les Miserables and in Krestovskij's Peterburgskie truscoby JF - Zeitschrift für Slawistik Y1 - 2013 U6 - https://doi.org/10.1524/slaw.2013.58.4.391 SN - 0044-3506 VL - 58 IS - 4 SP - 391 EP - 416 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Kosta, Peter T1 - Ambiguity and humor in translation JF - Zeitschrift für Slawistik Y1 - 2013 U6 - https://doi.org/10.1524/slaw.2013.58.3.297 SN - 0044-3506 VL - 58 IS - 3 SP - 297 EP - 324 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Goppelsroeder, Fabian T1 - Bloom and the metabolism of modern JF - Poetica : Zeitschrift für Sprach- und Literaturwissenschaft Y1 - 2013 SN - 0303-4178 VL - 45 IS - 3-4 SP - 377 EP - 389 PB - Fink CY - Paderborn ER - TY - JOUR A1 - Oberhänsli, Roland A1 - Koralay, E. A1 - Candan, Osman A1 - Pourteau, Amaury A1 - Bousquet, Romain T1 - Late cretaceous eclogitic high-pressure relics in the Bitlis Massif JF - Geodinamica acta : revue de géologie dynamique et de géographie physique N2 - A new occurrence of eclogites was found in the Kesandere valley in the eastern most part of the Bitlis complex, SE Anatolia. These high-pressure (HP) relics were preserved in calc-arenitic metasediments within the high-grade metamorphic basement of the Bitlis complex. The eclogitic parageneses were strongly overprinted during decompression and heating. These new eclogites locality complements the evidence of blueschist-facies metamorphism documented recently in the meta-sedimentary cover sequence of this part of the Bitlis complex. Thermodynamic calculations suggest peak conditions of ca. 480-540 degrees C/1.9-2.4GPa. New U/Pb dates of 84.4 +/-.9 and 82.4 +/-.9Ma were obtained on zircons from two Kesandere eclogite samples. On the basis of geochemical criteria, these dates are interpreted to represent zircon crystallization during the eclogitic peak stage. Kesandere eclogites differ from those previously described in the western Bitlis complex (Mt. Gablor locality) in terms of lithologic association, protolithic origin, and peak P-T conditions (600-650 degrees C/1.0-2.0GPa, respectively). On the other hand, eclogitic metamorphism of Kesandere metasediments occurred shortly before blueschist-facies metamorphism of the sedimentary cover (79-74Ma Ar-40/Ar-39 white mica). Therefore, the exhumation of Kesandere eclogites started between ca. 82 and 79Ma, while the meta-sedimentary cover was being buried. During this short time span, Kesandere eclogite were likely uplifted from similar to 65 to 35km depth, indicating a syn-subduction exhumation rate of similar to 4.3mm/a. Subsequently, eclogite- and blueschist-facies rocks were likely retrogressed contemporarily during collision-type metamorphism (around 72-69Ma). The Bitlis HP rocks thus sample a subduction zone that separated the Bitlis-Puturge (Bistun?) block from the South-Armenian block, further north. To the south, Eocene metasediments of the Urse formation are imbricated below the Bitlis complex. They contain (post Eocene) blueschists, testifying separation from the Arabian plate and southward migration of the subduction zone. The HT overprint of Kesandere eclogites can be related to the asthenospheric flow provoked by subducting slab retreat or break off. KW - eclogites KW - zircon KW - U KW - Pb ages KW - E Anatolia KW - subduction-collision Y1 - 2013 U6 - https://doi.org/10.1080/09853111.2013.858951 SN - 0985-3111 SN - 1778-3593 VL - 26 IS - 3-4 SP - 175 EP - 190 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Vöth, Markus A1 - Herbst, Uta A1 - Liess, Frank T1 - We know exactly what you want the development of a completely individualised conjoint analysis JF - International journal of market research N2 - Improving the predictive validity of conjoint analysis has been an important research objective for many years. Whereas the majority of attempts have been different approaches to preference modelling, data collection or product presentation, only a few scholars have tried to improve predictive validity by individualising conjoint designs. This comes as a surprise because many markets have observed an augmented demand for customised products and highly heterogeneous customers' preferences. Against this background, the authors develop a conjoint variant based on a completely individualised conjoint design. More concretely, the new approach not only individualises the attributes, but also the attribute levels. The results of a comprehensive empirical study yield a significantly higher validity than existing standardised-level conjoint approaches. Consequently, they help marketers to gain deeper insights into their customers' preferences. Y1 - 2013 U6 - https://doi.org/10.2501/IJMR-2013-038 SN - 1470-7853 VL - 55 IS - 3 SP - 437 EP - 458 PB - Market Research Society CY - London ER - TY - JOUR A1 - Basso, Heitor Cury A1 - Qiu, Xunlin A1 - Wirges, Werner A1 - Gerhard, Reimund T1 - Temporal evolution of the re-breakdown voltage in small gaps from nanoseconds to milliseconds JF - Applied physics letters N2 - A detailed understanding of electric breakdown in dielectrics is of scientific and technological interest. In gaseous dielectrics, a so-called re-breakdown is sometimes observed after extinction of the previous discharge. Although time-dependent re-breakdown voltage is essentially known, its behavior immediately after the previous discharge is not precisely understood. We present an electronic circuit for accurate measurements of the time-dependent re-breakdown voltage in small gaps from tens of nanoseconds to several milliseconds after the previous spark. Results from such experiments are compared with earlier findings, and relevant physical mechanisms such as heating of the gas, decay of the plasma, and ionization of excited atoms and molecules are discussed. It is confirmed that the thermal model is not valid at times below several microseconds. Y1 - 2013 U6 - https://doi.org/10.1063/1.4773518 SN - 0003-6951 VL - 102 IS - 1 PB - American Institute of Physics CY - Melville ER - TY - JOUR A1 - Schulz, Johannes H. P. A1 - Barkai, Eli A1 - Metzler, Ralf T1 - Aging effects and population splitting in single-particle trajectoryaverages JF - Physical review letters N2 - We study time averages of single particle trajectories in scale-free anomalous diffusion processes, in which the measurement starts at some time t(a) > 0 after initiation of the process at t = 0. Using aging renewal theory, we show that for such nonstationary processes a large class of observables are affected by a unique aging function, which is independent of boundary conditions or the external forces. Moreover, we discuss the implications of aging induced population splitting: with growing age ta of the process, an increasing fraction of particles remains motionless in a measurement of fixed duration. Consequences for single biomolecule tracking in live cells are discussed. Y1 - 2013 U6 - https://doi.org/10.1103/PhysRevLett.110.020602 SN - 0031-9007 SN - 1079-7114 VL - 110 IS - 2 PB - American Physical Society CY - College Park ER - TY - JOUR A1 - von der Lippe, Moritz A1 - Bullock, James M. A1 - Kowarik, Ingo A1 - Knopp, Tatjana A1 - Wichmann, Matthias T1 - Human-mediated dispersal of seeds by the airflow of vehicles JF - PLoS one N2 - Human-mediated dispersal is known as an important driver of long-distance dispersal for plants but underlying mechanisms have rarely been assessed. Road corridors function as routes of secondary dispersal for many plant species but the extent to which vehicles support this process remains unclear. In this paper we quantify dispersal distances and seed deposition of plant species moved over the ground by the slipstream of passing cars. We exposed marked seeds of four species on a section of road and drove a car along the road at a speed of 48 km/h. By tracking seeds we quantified movement parallel as well as lateral to the road, resulting dispersal kernels, and the effect of repeated vehicle passes. Median distances travelled by seeds along the road were about eight meters for species with wind dispersal morphologies and one meter for species without such adaptations. Airflow created by the car lifted seeds and resulted in longitudinal dispersal. Single seeds reached our maximum measuring distance of 45 m and for some species exceeded distances under primary dispersal. Mathematical models were fit to dispersal kernels. The incremental effect of passing vehicles on longitudinal dispersal decreased with increasing number of passes as seeds accumulated at road verges. We conclude that dispersal by vehicle airflow facilitates seed movement along roads and accumulation of seeds in roadside habitats. Dispersal by vehicle airflow can aid the spread of plant species and thus has wide implications for roadside ecology, invasion biology and nature conservation. Y1 - 2013 U6 - https://doi.org/10.1371/journal.pone.0052733 SN - 1932-6203 VL - 8 IS - 1 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Arlen, T. A1 - Aune, T. A1 - Beilicke, M. A1 - Benbow, W. A1 - Bouvier, A. A1 - Buckley, J. H. A1 - Bugaev, V. A1 - Cesarini, A. A1 - Ciupik, L. A1 - Connolly, M. P. A1 - Cui, W. A1 - Dickherber, R. A1 - Dumm, J. A1 - Errando, M. A1 - Falcone, A. A1 - Federici, S. A1 - Feng, Q. A1 - Finley, J. P. A1 - Finnegan, G. A1 - Fortson, L. A1 - Furniss, A. A1 - Galante, N. A1 - Gall, D. A1 - Griffin, S. A1 - Grube, J. A1 - Gyuk, G. A1 - Hanna, D. A1 - Holder, J. A1 - Humensky, T. B. A1 - Kaaret, P. A1 - Karlsson, N. A1 - Kertzman, M. A1 - Khassen, Y. A1 - Kieda, D. A1 - Krawczynski, H. A1 - Krennrich, F. A1 - Maier, G. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Nelson, T. A1 - de Bhroithe, A. O'Faolain A1 - Ong, R. A. A1 - Orr, M. A1 - Park, N. A1 - Perkins, J. S. A1 - Pichel, A. A1 - Pohl, Martin A1 - Prokoph, H. A1 - Quinn, J. A1 - Ragan, K. A1 - Reyes, L. C. A1 - Reynolds, P. T. A1 - Roache, E. A1 - Saxon, D. B. A1 - Schroedter, M. A1 - Sembroski, G. H. A1 - Staszak, D. A1 - Telezhinsky, Igor O. A1 - Tesic, G. A1 - Theiling, M. A1 - Tsurusaki, K. A1 - Varlotta, A. A1 - Vincent, S. A1 - Wakely, S. P. A1 - Weekes, T. C. A1 - Weinstein, A. A1 - Welsing, R. A1 - Williams, D. A. A1 - Zitzer, B. A1 - Jorstad, S. G. A1 - MacDonald, N. R. A1 - Marscher, A. P. A1 - Smith, P. S. A1 - Walker, R. C. A1 - Hovatta, T. A1 - Richards, J. A1 - Max-Moerbeck, W. A1 - Readhead, A. A1 - Lister, M. L. A1 - Kovalev, Y. Y. A1 - Pushkarev, A. B. A1 - Gurwell, M. A. A1 - Lahteenmaki, A. A1 - Nieppola, E. A1 - Tornikoski, M. A1 - Jarvela, E. T1 - Rapid TeV Gamma-Ray flaring of bl lacertae JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We report on the detection of a very rapid TeV gamma-ray flare from BL Lacertae on 2011 June 28 with the Very Energetic Radiation Imaging Telescope Array System (VERITAS). The flaring activity was observed during a 34.6 minute exposure, when the integral flux above 200 GeV reached (3.4 +/- 0.6) x 10(-6) photons m(-2) s(-1), roughly 125% of the Crab Nebula flux measured by VERITAS. The light curve indicates that the observations missed the rising phase of the flare but covered a significant portion of the decaying phase. The exponential decay time was determined to be 13 +/- 4 minutes, making it one of the most rapid gamma-ray flares seen from a TeV blazar. The gamma-ray spectrum of BL Lacertae during the flare was soft, with a photon index of 3.6 +/- 0.4, which is in agreement with the measurement made previously by MAGIC in a lower flaring state. Contemporaneous radio observations of the source with the Very Long Baseline Array revealed the emergence of a new, superluminal component from the core around the time of the TeV gamma-ray flare, accompanied by changes in the optical polarization angle. Changes in flux also appear to have occurred at optical, UV, and GeV gamma-ray wavelengths at the time of the flare, although they are difficult to quantify precisely due to sparse coverage. A strong flare was seen at radio wavelengths roughly four months later, which might be related to the gamma-ray flaring activities. We discuss the implications of these multiwavelength results. KW - galaxies: active KW - galaxies: individual (BL Lacertae, VER J2202+422) KW - gamma rays: galaxies Y1 - 2013 U6 - https://doi.org/10.1088/0004-637X/762/2/92 SN - 0004-637X VL - 762 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Godec, Aljaz A1 - Metzler, Ralf T1 - Finite-Time effects and ultraweak ergodicity breaking in superdiffusive dynamics JF - Physical review letters N2 - We study the ergodic properties of superdiffusive, spatiotemporally coupled Levy walk processes. For trajectories of finite duration, we reveal a distinct scatter of the scaling exponents of the time averaged mean squared displacement (delta x(2)) over bar around the ensemble value 3 - alpha (1 < alpha < 2) ranging from ballistic motion to subdiffusion, in strong contrast to the behavior of subdiffusive processes. In addition we find a significant dependence of the average of (delta x(2)) over bar over an ensemble of trajectories as a function of the finite measurement time. This so-called finite-time amplitude depression and the scatter of the scaling exponent is vital in the quantitative evaluation of superdiffusive processes. Comparing the long time average of the second moment with the ensemble mean squared displacement, these only differ by a constant factor, an ultraweak ergodicity breaking. Y1 - 2013 U6 - https://doi.org/10.1103/PhysRevLett.110.020603 SN - 0031-9007 VL - 110 IS - 2 PB - American Physical Society CY - College Park ER - TY - JOUR A1 - Liu, Chun A1 - Sibly, Richard M. A1 - Grimm, Volker A1 - Thorbek, Pernille T1 - Linking pesticide exposure and spatial dynamics an individual-based model of wood mouse (Apodemus sylvaticus) populations in agricultural landscapes JF - Ecological modelling : international journal on ecological modelling and engineering and systems ecolog N2 - The wood mouse is a common and abundant species in agricultural landscape and is a focal species in pesticide risk assessment. Empirical studies on the ecology of the wood mouse have provided sufficient information for the species to be modelled mechanistically. An individual-based model was constructed to explicitly represent the locations and movement patterns of individual mice. This together with the schedule of pesticide application allows prediction of the risk to the population from pesticide exposure. The model included life-history traits of wood mice as well as typical landscape dynamics in agricultural farmland in the UK. The model obtains a good fit to the available population data and is fit for risk assessment purposes. It can help identify spatio-temporal situations with the largest potential risk of exposure and enables extrapolation from individual-level endpoints to population-level effects. Largest risk of exposure to pesticides was found when good crop growth in the "sink" fields coincided with high "source" population densities in the hedgerows. KW - Population dynamics KW - Pesticides KW - Ecological risk assessment KW - Habitat choice KW - Agent-based model KW - NetLogo Y1 - 2013 U6 - https://doi.org/10.1016/j.ecolmodel.2012.09.016 SN - 0304-3800 VL - 248 IS - 2 SP - 92 EP - 102 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Moskalik, Mikhail Yu A1 - Shainyan, Bagrat A. A1 - Astakhova, Vera V. A1 - Schilde, Uwe T1 - Oxidative addition of trifluoromethanesulfonamide to cycloalkadienes JF - Tetrahedron N2 - In the oxidative system (t-BuOCl+NaI) trifluoromethanesulfonamide is regio- and stereoselectively added to only one double bond of cyclopentadiene and 1,3-cyclohexadiene giving rise to 1,1,1-trifluoro-N-(5-iodocyclopent-2-en-1-yl)methanesulfonamide 7 and trans-N,N'-cyclohex-3-en-1,2-diylbis(1,1,1-trifluoromethanesulfonamide) 8. The structure of 7 and 8 was determined by X-ray, NMR, and MS. With 1,4-cyclohexadiene, addition to both double bonds occurs with the formation of N,N'-(4-chloro-5-iodocyclohexan-1,2-diyl)bis(1,1,1-trifluoromethanesulfonamide) 9. Under the action of sodium iodide in acetone, the latter product undergoes halogenophilic attack with the reduction of the CHI group and elimination of HCl to give trans-N,N'-cyclohex-4-en-1,2-diylbis(1,1,1-trifluoromethanesulfonamide) 10, whose structure was also determined by X-ray analysis. 1,3,5-Cycloheptatriene under these conditions is oxidized to benzaldehyde and does not react with trifluoromethanesulfonamide. KW - Trifluoromethanesulfonamide KW - Cyclodienes KW - 1,2-Disulfonamides KW - Allylamides KW - X-ray Y1 - 2013 U6 - https://doi.org/10.1016/j.tet.2012.10.099 SN - 0040-4020 VL - 69 IS - 2 SP - 705 EP - 711 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Heckmann, Tobias A1 - Schwanghart, Wolfgang T1 - Geomorphic coupling and sediment connectivity in an alpine catchment - Exploring sediment cascades using graph theory JF - Geomorphology : an international journal on pure and applied geomorphology N2 - Through their relevance for sediment budgets and the sensitivity of geomorphic systems, geomorphic coupling and (sediment) connectivity represent important topics in geomorphology. Since the introduction of the systems perspective to physical geography by Chorley and Kennedy (1971), a catchment has been perceived as consisting of landscape elements (e.g. landforms, subcatchments) that are coupled by geomorphic processes through sediment transport. In this study, we present a novel application of mathematical graph theory to explore the network structure of coarse sediment pathways in a central alpine catchment. Numerical simulation models for rockfall, debris flows, and (hillslope and channel) fluvial processes are used to establish a spatially explicit graph model of sediment sources, pathways and sinks. The raster cells of a digital elevation model form the nodes of this graph, and simulated sediment trajectories represent the corresponding edges. Model results are validated by visual comparison with the field situation and aerial photos. The interaction of sediment pathways, i.e. where the deposits of a geomorphic process form the sources of another process, forms sediment cascades, represented by paths (a succession of edges) in the graph model. We show how this graph can be used to explore upslope (contributing area) and downslope (source to sink) functional connectivity by analysing its nodes, edges and paths. The analysis of the spatial distribution, composition and frequency of sediment cascades yields information on the relative importance of geomorphic processes and their interaction (however regardless of their transport capacity). In the study area, the analysis stresses the importance of mass movements and their interaction, e.g. the linkage of large rockfall source areas to debris flows that potentially enter the channel network. Moreover, it is shown that only a small percentage of the study area is coupled to the channel network which itself is longitudinally disconnected by natural and anthropogenic barriers. Besides the case study, we discuss the methodological framework and alternatives for node and edge representations of graph models in geomorphology. We conclude that graph theory provides an excellent methodological framework for the analysis of geomorphic systems, especially for the exploration of quantitative approaches towards sediment connectivity. KW - Geomorphic coupling KW - Sediment connectivity KW - Sediment cascades KW - Graph theory Y1 - 2013 U6 - https://doi.org/10.1016/j.geomorph.2012.10.033 SN - 0169-555X VL - 182 IS - 2 SP - 89 EP - 103 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kahmen, Ansgar A1 - Schefuss, Enno A1 - Sachse, Dirk T1 - Leaf water deuterium enrichment shapes leaf wax n-alkane delta D values of angiosperm plants I experimental evidence and mechanistic insights JF - Geochimica et cosmochimica acta : journal of the Geochemical Society and the Meteoritical Society N2 - Leaf wax n-alkanes of terrestrial plants are long-chain hydrocarbons that can persist in sedimentary records over geologic timescales. Since meteoric water is the primary source of hydrogen used in leaf wax synthesis, the hydrogen isotope composition (delta D value) of these biomarkers contains information on hydrological processes. Consequently, leaf wax n-alkane delta D values have been advocated as powerful tools for paleohydrological research. The exact kind of hydrological information that is recorded in leaf wax n-alkanes remains, however, unclear because critical processes that determine their delta D values have not yet been resolved. In particular the effects of evaporative deuterium (D)-enrichment of leaf water on the delta D values of leaf wax n-alkanes have not yet been directly assessed and quantified. Here we present the results of a study where we experimentally tested if and by what magnitude evaporative D-enrichment of leaf water affects the delta D of leaf wax n-alkanes in angiosperm C3 and C4 plants. Our study revealed that n-alkane delta D values of all plants that we investigated were affected by evaporative D-enrichment of leaf water. For dicotyledonous plants we found that the full extent of leaf water evaporative D-enrichment is recorded in leaf wax n-alkane delta D values. For monocotyledonous plants we found that between 18% and 68% of the D-enrichment in leaf water was recorded in the delta D values of their n-alkanes. We hypothesize that the different magnitudes by which evaporative D-enrichment of leaf water affects the delta D values of leaf wax n-alkanes in monocotyledonous and dicotyledonous plants is the result of differences in leaf growth and development between these plant groups. Our finding that the evaporative D-enrichment of leaf water affects the delta D values of leaf wax n-alkanes in monocotyledonous and dicotyledonous plants albeit at different magnitudes - has important implications for the interpretation of leaf wax n-alkane delta D values from paleohydrological records. In addition, our finding opens the door to employ delta D values of leaf wax n-alkanes as new ecohydrological proxies for evapotranspiration that can be applied in contemporary plant and ecosystem research. Y1 - 2013 U6 - https://doi.org/10.1016/j.gca.2012.09.003 SN - 0016-7037 VL - 111 SP - 39 EP - 49 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Unuabonah, Emmanuel Iyayi A1 - Olu-Owolabi, Bamidele I. A1 - Taubert, Andreas A1 - Omolehin, Elizabeth B. A1 - Adebowale, Kayode O. T1 - SAPK a novel composite resin for water treatment with very high Zn2+, Cd2+, and Pb2+ adsorption capacity JF - Industrial & engineering chemistry research N2 - A new sulfonated aniline-modified poly(vinyl alcohol)/K-feldspar (SAPK) composite was prepared. The cation-exchange capacity of the composite was found to be S times that of neat feldspar. The specific surface area and point of zero charge also changed significantly upon modification, from 15.6 +/- 0.1 m(2)/g and 2.20 (K-feldspar) to 73.6 +/- 0.3 m(2)/g and 1.91 (SAPK). Zn2+, Cd2+, and Pb2+ adsorption was found to be largely independent of pH, and the metal adsorption rate on SAPK was higher than that on neat feldspar. This particularly applies to the initial adsorption rates. The adsorption process involves both film and pore diffusion; film diffusion initially controls the adsorption. The Freundlich and Langmuir models were found to fit metal-ion adsorption on SAPK most accurately. Adsorption on neat feldspar was best fitted with a Langmuir model, indicating the formation of adsorbate monolayers. Both pure feldspar and SAPK showed better selectivity for Pb2+ than for Cd2+ or Zn2+. Y1 - 2013 U6 - https://doi.org/10.1021/ie3024577 SN - 0888-5885 VL - 52 IS - 2 SP - 578 EP - 585 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Schubert, Marcel A1 - Preis, Eduard A1 - Blakesley, James C. A1 - Pingel, Patrick A1 - Scherf, Ullrich A1 - Neher, Dieter T1 - Mobility relaxation and electron trapping in a donor/acceptor copolymer JF - Physical review : B, Condensed matter and materials physics N2 - To address the nature of charge transport and the origin of severe (intrinsic) trapping in electron-transporting polymers, transient and steady-state charge transport measurements have been conducted on the prototype donor/acceptor copolymer poly[2,7-(9,9-dialkyl-fluorene)-alt-5,5-(4',7'-di-2-thienyl-2',1',3'-benzothiadiazole)] (PFTBTT). A charge-generation layer technique is used to selectively address transport of the desired charge carrier type, to perform time-of-flight measurements on samples with < 200 nm thickness, and to combine the time-of-flight and the photocharge extraction by linearly increasing voltage (photo-CELIV) techniques to investigate charge carrier dynamics over a wide time range. Significant trapping of free electrons is observed in the bulk of dioctyl-substituted PFTBTT (alt-PF8TBTT), introducing a strong relaxation of the charge carrier mobility with time. We used Monte-Carlo simulation to simulate the measured transient data and found that all measurements can be modeled with a single parameter set, with the charge transport behavior determined by multiple trapping and detrapping of electrons in an exponential trap distribution. The influence of the concomitant mobility relaxation on the transient photocurrent characteristics in photo-CELIV experiments is discussed and shown to explain subtle features that were seen in former publications but were not yet assigned to electron trapping. Comparable studies on PFTBTT copolymers with chemical modifications of the side chains and backbone suggest that the observed electron trapping is not caused by a distinct chemical species but rather is related to interchain interactions. Y1 - 2013 U6 - https://doi.org/10.1103/PhysRevB.87.024203 SN - 1098-0121 VL - 87 IS - 2 PB - American Physical Society CY - College Park ER - TY - JOUR A1 - Bauer, Maximilian A1 - Metzler, Ralf T1 - In vivo facilitated diffusion model JF - PLoS one N2 - Under dilute in vitro conditions transcription factors rapidly locate their target sequence on DNA by using the facilitated diffusion mechanism. However, whether this strategy of alternating between three-dimensional bulk diffusion and one-dimensional sliding along the DNA contour is still beneficial in the crowded interior of cells is highly disputed. Here we use a simple model for the bacterial genome inside the cell and present a semi-analytical model for the in vivo target search of transcription factors within the facilitated diffusion framework. Without having to resort to extensive simulations we determine the mean search time of a lac repressor in a living E. coli cell by including parameters deduced from experimental measurements. The results agree very well with experimental findings, and thus the facilitated diffusion picture emerges as a quantitative approach to gene regulation in living bacteria cells. Furthermore we see that the search time is not very sensitive to the parameters characterizing the DNA configuration and that the cell seems to operate very close to optimal conditions for target localization. Local searches as implied by the colocalization mechanism are only found to mildly accelerate the mean search time within our model. Y1 - 2013 U6 - https://doi.org/10.1371/journal.pone.0053956 SN - 1932-6203 VL - 8 IS - 1 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Bertz, Andreas A1 - Wöhl-Bruhn, Stefanie A1 - Miethe, Sebastian A1 - Tiersch, Brigitte A1 - Koetz, Joachim A1 - Hust, Michael A1 - Bunjes, Heike A1 - Menzel, Henning T1 - Encapsulation of proteins in hydrogel carrier systems for controlled drug delivery influence of network structure and drug size on release rate JF - Journal of biotechnology N2 - Novel hydrogels based on hydroxyethyl starch modified with polyethylene glycol methacrylate (HES-P(EG)(6)MA) were developed as delivery system for the controlled release of proteins. Since the drug release behavior is supposed to be related to the pore structure of the hydrogel network the pore sizes were determined by cryo-SEM, which is a mild technique for imaging on a nanometer scale. The results showed a decreasing pore size and an increase in pore homogeneity with increasing polymer concentration. Furthermore, the mesh sizes of the hydrogels were calculated based on swelling data. Pore and mesh size were significantly different which indicates that both structures are present in the hydrogel. The resulting structural model was correlated with release data for bulk hydrogel cylinders loaded with FITC-dextran and hydrogel microspheres loaded with FITC-IgG and FITC-dextran of different molecular size. The initial release depended much on the relation between hydrodynamic diameter and pore size while the long term release of the incorporated substances was predominantly controlled by degradation of the network of the much smaller meshes. KW - Hydrogel KW - Hydrogel microspheres KW - Network structure KW - Release studies KW - Protein delivery KW - Mesh size Y1 - 2013 U6 - https://doi.org/10.1016/j.jbiotec.2012.06.036 SN - 0168-1656 VL - 163 IS - 2 SP - 243 EP - 249 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Neigenfind, Jost A1 - Grimbs, Sergio A1 - Nikoloski, Zoran T1 - On the relation between reactions and complexes of (bio)chemical reaction networks JF - Journal of theoretical biology N2 - Robustness of biochemical systems has become one of the central questions in systems biology although it is notoriously difficult to formally capture its multifaceted nature. Maintenance of normal system function depends not only on the stoichiometry of the underlying interrelated components, but also on the multitude of kinetic parameters. Invariant flux ratios, obtained within flux coupling analysis, as well as invariant complex ratios, derived within chemical reaction network theory, can characterize robust properties of a system at steady state. However, the existing formalisms for the description of these invariants do not provide full characterization as they either only focus on the flux-centric or the concentration-centric view. Here we develop a novel mathematical framework which combines both views and thereby overcomes the limitations of the classical methodologies. Our unified framework will be helpful in analyzing biologically important system properties. KW - Metabolic network KW - Mass action system KW - Flux coupling analysis KW - Chemical reaction network theory Y1 - 2013 U6 - https://doi.org/10.1016/j.jtbi.2012.10.016 SN - 0022-5193 VL - 317 IS - 2 SP - 359 EP - 365 PB - Elsevier CY - London ER - TY - JOUR A1 - Huebener, R. A1 - Mari, Andrea A1 - Eisert, Jens T1 - Wick's theorem for matrix product states JF - Physical review letters N2 - Matrix product states and their continuous analogues are variational classes of states that capture quantum many-body systems or quantum fields with low entanglement; they are at the basis of the density-matrix renormalization group method and continuous variants thereof. In this work we show that, generically, N-point functions of arbitrary operators in discrete and continuous translation invariant matrix product states are completely characterized by the corresponding two- and three-point functions. Aside from having important consequences for the structure of correlations in quantum states with low entanglement, this result provides a new way of reconstructing unknown states from correlation measurements, e. g., for one-dimensional continuous systems of cold atoms. We argue that such a relation of correlation functions may help in devising perturbative approaches to interacting theories. Y1 - 2013 U6 - https://doi.org/10.1103/PhysRevLett.110.040401 SN - 0031-9007 VL - 110 IS - 4 PB - American Physical Society CY - College Park ER - TY - JOUR A1 - Abramowski, Attila A1 - Acero, F. A1 - Aharonian, Felix A. A1 - Akhperjanian, A. G. A1 - Anton, Gisela A1 - Balenderan, Shangkari A1 - Balzer, Arnim A1 - Barnacka, Anna A1 - Becherini, Yvonne A1 - Tjus, J. Becker A1 - Bernlöhr, K. A1 - Birsin, E. A1 - Biteau, Jonathan A1 - Bochow, A. A1 - Boisson, Catherine A1 - Bolmont, J. A1 - Bordas, Pol A1 - Brucker, J. A1 - Brun, Francois A1 - Brun, Pierre A1 - Bulik, Tomasz A1 - Carrigan, Svenja A1 - Casanova, Sabrina A1 - Cerruti, M. A1 - Chadwick, Paula M. A1 - Chaves, Ryan C. G. A1 - Cheesebrough, A. A1 - Colafrancesco, Sergio A1 - Cologna, Gabriele A1 - Conrad, Jan A1 - Couturier, C. A1 - Dalton, M. A1 - Daniel, M. K. A1 - Davids, I. D. A1 - Degrange, B. A1 - Deil, C. A1 - deWilt, P. A1 - Dickinson, H. J. A1 - Djannati-Ataï, A. A1 - Domainko, W. A1 - Drury, L. O'C. A1 - Dubus, G. A1 - Dutson, K. A1 - Dyks, J. A1 - Dyrda, M. A1 - Egberts, Kathrin A1 - Eger, P. A1 - Espigat, P. A1 - Fallon, L. A1 - Farnier, C. A1 - Fegan, S. A1 - Feinstein, F. A1 - Fernandes, M. V. A1 - Fernandez, D. A1 - Fiasson, A. A1 - Fontaine, G. A1 - Foerster, A. A1 - Fussling, Matthias A1 - Gajdus, M. A1 - Gallant, Y. A. A1 - Garrigoux, T. A1 - Gast, H. A1 - Giebels, B. A1 - Glicenstein, J. F. A1 - Glueck, B. A1 - Goering, D. A1 - Grondin, M. -H. A1 - Haeffner, S. A1 - Hague, J. D. A1 - Hahn, J. A1 - Hampf, D. A1 - Harris, J. A1 - Heinz, S. A1 - Heinzelmann, G. A1 - Henri, G. A1 - Hermann, G. A1 - Hillert, A. A1 - Hinton, James Anthony A1 - Hofmann, W. A1 - Hofverberg, P. A1 - Holler, M. A1 - Horns, D. A1 - Jacholkowska, A. A1 - Jahn, C. A1 - Jamrozy, M. A1 - Jung, I. A1 - Kastendieck, M. A. A1 - Katarzynski, K. A1 - Katz, U. A1 - Kaufmann, S. A1 - Khelifi, B. A1 - Klepser, S. A1 - Klochkov, D. A1 - Kluzniak, W. A1 - Kneiske, T. A1 - Komin, Nu A1 - Kosack, K. A1 - Kossakowski, R. A1 - Krayzel, F. A1 - Krueger, P. P. A1 - Laffon, H. A1 - Lamanna, G. A1 - Lefaucheur, J. A1 - Lemoine-Goumard, M. A1 - Lenain, J. -P. A1 - Lennarz, D. A1 - Lohse, T. A1 - Lopatin, A. A1 - Lu, C. -C. A1 - Marandon, V. A1 - Marcowith, Alexandre A1 - Masbou, J. A1 - Maurin, G. A1 - Maxted, N. A1 - Mayer, M. A1 - McComb, T. J. L. A1 - Medina, M. C. A1 - Mehault, J. A1 - Menzler, U. A1 - Moderski, R. A1 - Mohamed, M. A1 - Moulin, Emmanuel A1 - Naumann, C. L. A1 - Naumann-Godo, M. A1 - de Naurois, M. A1 - Nedbal, D. A1 - Nekrassov, D. A1 - Nguyen, N. A1 - Niemiec, J. A1 - Nolan, S. J. A1 - Ohm, S. A1 - Awilhelmi, E. de Ona A1 - Opitz, B. A1 - Ostrowski, M. A1 - Oya, I. A1 - Panter, M. A1 - Parsons, R. D. A1 - Arribas, M. Paz A1 - Pekeur, N. W. A1 - Pelletier, G. A1 - Perez, J. A1 - Petrucci, P. -O. A1 - Peyaud, B. A1 - Pita, S. A1 - Puehlhofer, G. A1 - Punch, M. A1 - Quirrenbach, A. A1 - Raue, M. A1 - Reimer, A. A1 - Reimer, O. A1 - Renaud, M. A1 - de los Reyes, R. A1 - Rieger, F. A1 - Ripken, J. A1 - Rob, L. A1 - Rosier-Lees, S. A1 - Rowell, G. A1 - Rudak, B. A1 - Rulten, C. B. A1 - Sahakian, V. A1 - Sanchez, David M. A1 - Santangelo, Andrea A1 - Schlickeiser, R. A1 - Schulz, A. A1 - Schwanke, U. A1 - Schwarzburg, S. A1 - Schwemmer, S. A1 - Sheidaei, F. A1 - Skilton, J. L. A1 - Sol, H. A1 - Spengler, G. A1 - Stawarz, L. A1 - Steenkamp, R. A1 - Stegmann, Christian A1 - Stinzing, F. A1 - Stycz, K. A1 - Sushch, Iurii A1 - Szostek, A. A1 - Tavernet, J. -P. A1 - Terrier, R. A1 - Tluczykont, M. A1 - Trichard, C. A1 - Valerius, K. A1 - van Eldik, C. A1 - Vasileiadis, G. A1 - Venter, C. A1 - Viana, A. A1 - Vincent, P. A1 - Voelk, H. J. A1 - Volpe, F. A1 - Vorobiov, S. A1 - Vorster, M. A1 - Wagner, S. J. A1 - Ward, M. A1 - White, R. A1 - Wierzcholska, A. A1 - Wouters, D. A1 - Zacharias, M. A1 - Zajczyk, A. A1 - Zdziarski, A. A. A1 - Zech, Alraune A1 - Zechlin, H. -S. T1 - Search for Photon-Linelike Signatures from Dark Matter Annihilations with H.E.S.S. JF - Physical review letters N2 - Gamma-ray line signatures can be expected in the very-high-energy (E-gamma > 100 GeV) domain due to self-annihilation or decay of dark matter (DM) particles in space. Such a signal would be readily distinguishable from astrophysical gamma-ray sources that in most cases produce continuous spectra that span over several orders of magnitude in energy. Using data collected with the H. E. S. S. gamma-ray instrument, upper limits on linelike emission are obtained in the energy range between similar to 500 GeV and similar to 25 TeV for the central part of the Milky Way halo and for extragalactic observations, complementing recent limits obtained with the Fermi-LAT instrument at lower energies. No statistically significant signal could be found. For monochromatic gamma-ray line emission, flux limits of (2 x 10(-7)-2 x 10(-5)) m(-2)s(-1)sr(-1) and (1 x 10(-8)- 2 x 10(-6)) m(-2)s(-1)sr(-1) are obtained for the central part of the Milky Way halo and extragalactic observations, respectively. For a DM particle mass of 1 TeV, limits on the velocity- averaged DM annihilation cross section (chi chi ->gamma gamma) reach similar to 10(-27)cm(3)s(-1), based on the Einasto parametrization of the Galactic DM halo density profile. DOI: 10.1103/PhysRevLett.110.041301 Y1 - 2013 U6 - https://doi.org/10.1103/PhysRevLett.110.041301 SN - 0031-9007 VL - 110 IS - 4 PB - American Physical Society CY - College Park ER - TY - JOUR A1 - Geissler, Daniel A1 - Stufler, Stefan A1 - Löhmannsröben, Hans-Gerd A1 - Hildebrandt, Niko T1 - Six-color time-resolved forster resonance energy transfer for ultrasensitive multiplexed biosensing JF - Journal of the American Chemical Society N2 - Simultaneous monitoring of multiple molecular interactions and multiplexed detection of several diagnostic biomarkers at very low concentrations have become important issues in advanced biological and chemical sensing. Here we present an optically multiplexed six-color Forster resonance energy transfer (FRET) biosensor for simultaneous monitoring of five different individual binding events. We combined simultaneous FRET from one Tb complex to five different organic dyes measured in a filter-based time-resolved detection format with a sophisticated spectral crosstalk correction, which results in very efficient background suppression. The advantages and robustness of the multiplexed FRET sensor were exemplified by analyzing a 15-component lung cancer immunoassay involving 10 different antibodies and five different tumor markers in a single 50 mu L human serum sample. The multiplexed biosensor offers clinically relevant detection limits in the low picomolar (ng/mL) concentration range for all five markers, thus providing an effective early screening tool for lung cancer with the possibility of distinguishing small-cell from non-small-cell lung carcinoma. This novel technology will open new doors for multiple biomarker diagnostics as well as multiplexed real-time imaging and spectroscopy. Y1 - 2013 U6 - https://doi.org/10.1021/ja310317n SN - 0002-7863 VL - 135 IS - 3 SP - 1102 EP - 1109 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Krause, Florian A1 - Bekkering, Harold A1 - Lindemann, Oliver T1 - A feeling for numbers shared metric for symbolic and tactile numerosities JF - Frontiers in psychology N2 - Evidence for an approximate analog system of numbers has been provided by the finding that the comparison of two numerals takes longer and is more error-prone if the semantic distance between the numbers becomes smaller (so-called numerical distance effect). Recent embodied theories suggest that analog number representations are based on previous sensory experiences and constitute therefore a common magnitude metric shared by multiple domains. Here we demonstrate the existence of a cross-modal semantic distance effect between symbolic and tactile numerosities. Participants received tactile stimulations of different amounts of fingers while reading Arabic digits and indicated verbally whether the amount of stimulated fingers was different from the simultaneously presented digit or not. The larger the semantic distance was between the two numerosities, the faster and more accurate participants made their judgments. This cross-modal numerosity distance effect suggests a direct connection between tactile sensations and the concept of numerical magnitude. A second experiment replicated the interaction between symbolic and tactile numerosities and showed that this effect is not modulated by the participants' finger counting habits. Taken together, our data provide novel evidence for a shared metric for symbolic and tactile numerosities as an instance of an embodied representation of numbers. KW - number cognition KW - tactile perception KW - finger counting Y1 - 2013 U6 - https://doi.org/10.3389/fpsyg.2013.00007 SN - 1664-1078 VL - 4 IS - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Klingstrom, Tomas A1 - Soldatova, Larissa A1 - Stevens, Robert A1 - Roos, T. Erik A1 - Swertz, Morris A. A1 - Müller, Kristian M. A1 - Kalas, Matus A1 - Lambrix, Patrick A1 - Taussig, Michael J. A1 - Litton, Jan-Eric A1 - Landegren, Ulf A1 - Bongcam-Rudloff, Erik T1 - Workshop on laboratory protocol standards for the molecular methods database JF - New biotechnology N2 - Management of data to produce scientific knowledge is a key challenge for biological research in the 21st century. Emerging high-throughput technologies allow life science researchers to produce big data at speeds and in amounts that were unthinkable just a few years ago. This places high demands on all aspects of the workflow: from data capture (including the experimental constraints of the experiment), analysis and preservation, to peer-reviewed publication of results. Failure to recognise the issues at each level can lead to serious conflicts and mistakes; research may then be compromised as a result of the publication of non-coherent protocols, or the misinterpretation of published data. In this report, we present the results from a workshop that was organised to create an ontological data-modelling framework for Laboratory Protocol Standards for the Molecular Methods Database (MolMeth). The workshop provided a set of short- and long-term goals for the MolMeth database, the most important being the decision to use the established EXACT description of biomedical ontologies as a starting point. Y1 - 2013 U6 - https://doi.org/10.1016/j.nbt.2012.05.019 SN - 1871-6784 VL - 30 IS - 2 SP - 109 EP - 113 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Stoyanov, Hristiyan A1 - Kollosche, Matthias A1 - Risse, Sebastian A1 - Wache, Remi A1 - Kofod, Guggi T1 - Soft conductive elastomer materials for stretchable electronics and voltage controlled artificial muscles JF - Advanced materials N2 - Block copolymer elastomer conductors (BEC) are mixtures of block copolymers grafted with conducting polymers, which are found to support very large strains, while retaining a high level of conductivity. These novel materials may find use in stretchable electronics. The use of BEC is demonstrated in a capacitive strain sensor and in an artificial muscle of the dielectric elastomer actuator type, supporting more than 100% actuation strain and capacity strain sensitivity up to 300%. KW - soft electrical connections KW - stretchable electronics KW - elastic conductor KW - compliant electrodes Y1 - 2013 U6 - https://doi.org/10.1002/adma.201202728 SN - 0935-9648 VL - 25 IS - 4 SP - 578 EP - 583 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Beyene, Yonas A1 - Katoh, Shigehiro A1 - Wolde Gabriel, Giday A1 - Hart, William K. A1 - Uto, Kozo A1 - Sudo, Masafumi A1 - Kondo, Megumi A1 - Hyodo, Masayuki A1 - Renne, Paul R. A1 - Suwa, Gen A1 - Asfaw, Berhane T1 - The characteristics and chronology of the earliest. Acheulean at Konso, Ethiopia JF - Proceedings of the National Academy of Sciences of the United States of America N2 - The Acheulean technological tradition, characterized by a large (>10 cm) flake-based component, represents a significant technological advance over the Oldowan. Although stone tool assemblages attributed to the Acheulean have been reported from as early as circa 1.6-1.75 Ma, the characteristics of these earliest occurrences and comparisons with later assemblages have not been reported in detail. Here, we provide a newly established chronometric calibration for the Acheulean assemblages of the Konso Formation, southern Ethiopia, which span the time period similar to 1.75 to <1.0 Ma. The earliest Konso Acheulean is chronologically indistinguishable from the assemblage recently published as the world's earliest with an age of similar to 1.75 Ma at Kokiselei, west of Lake Turkana, Kenya. This Konso assemblage is characterized by a combination of large picks and crude bifaces/unifaces made predominantly on large flake blanks. An increase in the number of flake scars was observed within the Konso Formation handaxe assemblages through time, but this was less so with picks. The Konso evidence suggests that both picks and handaxes were essential components of the Acheulean from its initial stages and that the two probably differed in function. The temporal refinement seen, especially in the handaxe forms at Konso, implies enhanced function through time, perhaps in processing carcasses with long and stable cutting edges. The documentation of the earliest Acheulean at similar to 1.75 Ma in both northern Kenya and southern Ethiopia suggests that behavioral novelties were being established in a regional scale at that time, paralleling the emergence of Homo erectus-like hominid morphology. KW - chronostratigraphy KW - Early Pleistocene KW - lithic technology development Y1 - 2013 U6 - https://doi.org/10.1073/pnas.1221285110 SN - 0027-8424 VL - 110 IS - 5 SP - 1584 EP - 1591 PB - National Acad. of Sciences CY - Washington ER - TY - JOUR A1 - Ohliger, Matthias A1 - Nesme, V. A1 - Eisert, J. T1 - Efficient and feasible state tomography of quantum many-body systems JF - New journal of physics : the open-access journal for physics N2 - We present a novel method for performing quantum state tomography for many-particle systems, which are particularly suitable for estimating the states in lattice systems such as of ultra-cold atoms in optical lattices. We show that the need to measure a tomographically complete set of observables can be overcome by letting the state evolve under some suitably chosen random circuits followed by the measurement of a single observable. We generalize known results about the approximation of unitary two-designs, i.e. certain classes of random unitary matrices, by random quantum circuits and connect our findings to the theory of quantum compressed sensing. We show that for ultra-cold atoms in optical lattices established experimental techniques such as optical super-lattices, laser speckles and time-of-flight measurements are sufficient to perform fully certified, assumption-free tomography. This is possible without the need to address single sites in any step of the procedure. Combining our approach with tensor network methods-in particular, the theory of matrix product states-we identify situations where the effort of reconstruction is even constant in the number of lattice sites, allowing, in principle, to perform tomography on large-scale systems readily available in present experiments. Y1 - 2013 U6 - https://doi.org/10.1088/1367-2630/15/1/015024 SN - 1367-2630 VL - 15 IS - 5 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Huang, Shaochun A1 - Hattermann, Fred A1 - Krysanova, Valentina A1 - Bronstert, Axel T1 - Projections of climate change impacts on river flood conditions in Germany by combining three different RCMs with a regional eco-hydrological model JF - Climatic change : an interdisciplinary, intern. journal devoted to the description, causes and implications of climatic change N2 - A general increase in precipitation has been observed in Germany in the last century, and potential changes in flood generation and intensity are now at the focus of interest. The aim of the paper is twofold: a) to project the future flood conditions in Germany accounting for various river regimes (from pluvial to nival-pluvial regimes) and under different climate scenarios (the high, A2, low, B1, and medium, A1B, emission scenarios) and b) to investigate sources of uncertainty generated by climate input data and regional climate models. Data of two dynamical Regional Climate Models (RCMs), REMO (REgional Model) and CCLM (Cosmo-Climate Local Model), and one statistical-empirical RCM, Wettreg (Wetterlagenbasierte Regionalisierungsmethode: weather-type based regionalization method), were applied to drive the eco-hydrological model SWIM (Soil and Water Integrated Model), which was previously validated for 15 gauges in Germany. At most of the gauges, the 95 and 99 percentiles of the simulated discharge using SWIM with observed climate data had a good agreement with the observed discharge for 1961-2000 (deviation within +/- 10 %). However, the simulated discharge had a bias when using RCM climate as input for the same period. Generalized Extreme Value (GEV) distributions were fitted to the annual maximum series of river runoff for each realization for the control and scenario periods, and the changes in flood generation over the whole simulation time were analyzed. The 50-year flood values estimated for two scenario periods (2021-2060, 2061-2100) were compared to the ones derived from the control period using the same climate models. The results driven by the statistical-empirical model show a declining trend in the flood level for most rivers, and under all climate scenarios. The simulations driven by dynamical models give various change directions depending on region, scenario and time period. The uncertainty in estimating high flows and, in particular, extreme floods remains high, due to differences in regional climate models, emission scenarios and multi-realizations generated by RCMs. Y1 - 2013 U6 - https://doi.org/10.1007/s10584-012-0586-2 SN - 0165-0009 SN - 1573-1480 VL - 116 IS - 3-4 SP - 631 EP - 663 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Gechev, Tsanko S. A1 - Benina, Maria A1 - Obata, Toshihiro A1 - Tohge, Takayuki A1 - Neerakkal, Sujeeth A1 - Minkov, Ivan A1 - Hille, Jacques A1 - Temanni, Mohamed-Ramzi A1 - Marriott, Andrew S. A1 - Bergström, Ed A1 - Thomas-Oates, Jane A1 - Antonio, Carla A1 - Müller-Röber, Bernd A1 - Schippers, Jos H. M. A1 - Fernie, Alisdair A1 - Toneva, Valentina T1 - Molecular mechanisms of desiccation tolerance in the resurrection glacial relic Haberlea rhodopensis JF - Cellular and molecular life sciences N2 - Haberlea rhodopensis is a resurrection plant with remarkable tolerance to desiccation. Haberlea exposed to drought stress, desiccation, and subsequent rehydration showed no signs of damage or severe oxidative stress compared to untreated control plants. Transcriptome analysis by next-generation sequencing revealed a drought-induced reprogramming, which redirected resources from growth towards cell protection. Repression of photosynthetic and growth-related genes during water deficiency was concomitant with induction of transcription factors (members of the NAC, NF-YA, MADS box, HSF, GRAS, and WRKY families) presumably acting as master switches of the genetic reprogramming, as well as with an upregulation of genes related to sugar metabolism, signaling, and genes encoding early light-inducible (ELIP), late embryogenesis abundant (LEA), and heat shock (HSP) proteins. At the same time, genes encoding other LEA, HSP, and stress protective proteins were constitutively expressed at high levels even in unstressed controls. Genes normally involved in tolerance to salinity, chilling, and pathogens were also highly induced, suggesting a possible cross-tolerance against a number of abiotic and biotic stress factors. A notable percentage of the genes highly regulated in dehydration and subsequent rehydration were novel, with no sequence homology to genes from other plant genomes. Additionally, an extensive antioxidant gene network was identified with several gene families possessing a greater number of antioxidant genes than most other species with sequenced genomes. Two of the transcripts most abundant during all conditions encoded catalases and five more catalases were induced in water-deficient samples. Using the pharmacological inhibitor 3-aminotriazole (AT) to compromise catalase activity resulted in increased sensitivity to desiccation. Metabolome analysis by GC or LC-MS revealed accumulation of sucrose, verbascose, spermidine, and gamma-aminobutyric acid during drought, as well as particular secondary metabolites accumulating during rehydration. This observation, together with the complex antioxidant system and the constitutive expression of stress protective genes suggests that both constitutive and inducible mechanisms contribute to the extreme desiccation tolerance of H. rhodopensis. KW - Antioxidant genes KW - Catalase KW - Desiccation tolerance KW - Drought stress KW - Metabolome analysis KW - Resurrection plants Y1 - 2013 U6 - https://doi.org/10.1007/s00018-012-1155-6 SN - 1420-682X VL - 70 IS - 4 SP - 689 EP - 709 PB - Springer CY - Basel ER - TY - JOUR A1 - Naze, Yael A1 - Oskinova, Lidia M. A1 - Gosset, Eric T1 - A detailed x-ray investigation of zeta puppis - II. the variability on short and long timescales JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - Stellar winds are a crucial component of massive stars, but their exact properties still remain uncertain. To shed some light on this subject, we have analyzed an exceptional set of X-ray observations of zeta Puppis, one of the closest and brightest massive stars. The sensitive light curves that were derived reveal two major results. On the one hand, a slow modulation of the X-ray flux (with a relative amplitude of up to 15% over 16 hr in the 0.3-4.0 keV band) is detected. Its characteristic timescale cannot be determined with precision, but amounts from one to several days. It could be related to corotating interaction regions, known to exist in zeta Puppis from UV observations. Hour-long changes, linked to flares or to the pulsation activity, are not observed in the last decade covered by the XMM observations; the 17 hr tentative period, previously reported in a ROSAT analysis, is not confirmed either and is thus transient, at best. On the other hand, short-term changes are surprisingly small (<1% relative amplitude for the total energy band). In fact, they are compatible solely with the presence of Poisson noise in the data. This surprisingly low level of short-term variability, in view of the embedded wind-shock origin, requires a very high fragmentation of the stellar wind, for both absorbing and emitting features (>10(5) parcels, comparing with a two-dimensional wind model). This is the first time that constraints have been placed on the number of clumps in an O-type star wind and from X-ray observations. KW - stars: early-type KW - stars: individual (zeta Pup) KW - X-rays: stars Y1 - 2013 U6 - https://doi.org/10.1088/0004-637X/763/2/143 SN - 0004-637X VL - 763 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Trinh, Christopher Q. A1 - Ellis, Simon C. A1 - Bland-Hawthorn, Joss A1 - Lawrence, Jon S. A1 - Horton, Anthony J. A1 - Leon-Saval, Sergio G. A1 - Shortridge, Keith A1 - Bryant, Julia A1 - Case, Scott A1 - Colless, Matthew A1 - Couch, Warrick A1 - Freeman, Kenneth A1 - Löhmannsröben, Hans-Gerd A1 - Gers, Luke A1 - Glazebrook, Karl A1 - Haynes, Roger A1 - Lee, Steve A1 - O'Byrne, John A1 - Miziarski, Stan A1 - Roth, Martin M. A1 - Schmidt, Brian A1 - Tinney, Christopher G. A1 - Zheng, Jessica T1 - Gnosis - the first instrument to use fiber bragg gratings for OH suppression JF - The astronomical journal N2 - The near-infrared is an important part of the spectrum in astronomy, especially in cosmology because the light from objects in the early universe is redshifted to these wavelengths. However, deep near-infrared observations are extremely difficult to make from ground-based telescopes due to the bright background from the atmosphere. Nearly all of this background comes from the bright and narrow emission lines of atmospheric hydroxyl (OH) molecules. The atmospheric background cannot be easily removed from data because the brightness fluctuates unpredictably on short timescales. The sensitivity of ground-based optical astronomy far exceeds that of near-infrared astronomy because of this long-standing problem. GNOSIS is a prototype astrophotonic instrument that utilizes "OH suppression fibers" consisting of fiber Bragg gratings and photonic lanterns to suppress the 103 brightest atmospheric emission doublets between 1.47 and 1.7 mu m. GNOSIS was commissioned at the 3.9 m Anglo-Australian Telescope with the IRIS2 spectrograph to demonstrate the potential of OH suppression fibers, but may be potentially used with any telescope and spectrograph combination. Unlike previous atmospheric suppression techniques GNOSIS suppresses the lines before dispersion and in a manner that depends purely on wavelength. We present the instrument design and report the results of laboratory and on-sky tests from commissioning. While these tests demonstrated high throughput (approximate to 60%) and excellent suppression of the skylines by the OH suppression fibers, surprisingly GNOSIS produced no significant reduction in the interline background and the sensitivity of GNOSIS+IRIS2 is about the same as IRIS2. It is unclear whether the lack of reduction in the interline background is due to physical sources or systematic errors as the observations are detector noise dominated. OH suppression fibers could potentially impact ground-based astronomy at the level of adaptive optics or greater. However, until a clear reduction in the interline background and the corresponding increasing in sensitivity is demonstrated optimized OH suppression fibers paired with a fiber-fed spectrograph will at least provide a real benefit at low resolving powers. KW - atmospheric effects KW - infrared: diffuse background KW - instrumentation: miscellaneous Y1 - 2013 U6 - https://doi.org/10.1088/0004-6256/145/2/51 SN - 0004-6256 VL - 145 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Seifan, Merav A1 - Seifan, Tal A1 - Schiffers, Katja A1 - Jeltsch, Florian A1 - Tielboerger, Katja T1 - Beyond the competition-colonization trade-off - linking multiple trait response to disturbance characteristics JF - The American naturalist : a bi-monthly journal devoted to the advancement and correlation of the biological sciences N2 - Disturbances' role in shaping communities is well documented but highly disputed. We suggest replacing the overused two-trait trade-off approach with a functional group scheme, constructed from combinations of four key traits that represent four classes of species' responses to disturbances. Using model results and field observations from sites affected by two highly different disturbances, we demonstrated that popular dichotomous trade-offs are not sufficient to explain community dynamics, even if some emerge under certain conditions. Without disturbances, competition was only sufficient to predict species survival but not relative success, which required some escape mechanism (e.g., long-term dormancy). With highly predictable and large-scale disturbances, successful species showed a combination of high individual tolerance to disturbance and, more surprisingly, high competitive ability. When disturbances were less predictable, high individual tolerance and long-term seed dormancy were favored, due to higher environmental uncertainty. Our study demonstrates that theories relying on a small number of predefined trade-offs among traits (e.g., competition-colonization trade-off) may lead to unrealistic results. We suggest that the understanding of disturbance-community relationships can be significantly improved by employing sets of relevant trait assemblies instead of the currently common approach in which trade-offs are assumed in advance. KW - competition resistance trade-off KW - functional types KW - intermediate disturbance hypothesis KW - plant communities KW - species assemblies Y1 - 2013 U6 - https://doi.org/10.1086/668844 SN - 0003-0147 VL - 181 IS - 2 SP - 151 EP - 160 PB - Univ. of Chicago Press CY - Chicago ER - TY - JOUR A1 - Salert, Beatrice Ch. D. A1 - Krueger, Hartmut A1 - Bagnich, Sergey A. A1 - Unger, Thomas A1 - Jaiser, Frank A1 - Al-Sa'di, Mahmoud A1 - Neher, Dieter A1 - Hayer, Anna A1 - Eberle, Thomas T1 - New polymer matrix system for phosphorescent organic light-emitting diodes and the role of the small molecular co-host JF - Journal of polymer science : A, Polymer chemistry N2 - A new matrix system for phosphorescent organic light-emitting diodes (OLEDs) based on an electron transporting component attached to an inert polymer backbone, an electronically neutral co-host, and a phosphorescent dye that serves as both emitter and hole conductor are presented. The inert co-host is used either as small molecules or covalently connected to the same chain as the electron-transporting host. The use of a small molecular inert co-host in the active layer is shown to be highly advantageous in comparison to a purely polymeric matrix bearing the same functionalities. Analysis of the dye phosphorescence decay in pure polymer, small molecular co-host film, and their blend lets to conclude that dye molecules distribute mostly in the small molecular co-host phase, where the co-host prevents agglomeration and self-quenching of the phosphorescence as well as energy transfer to the electron transporting units. In addition, the co-host accumulates at the anode interface where it acts as electron blocking layer and improves hole injection. This favorable phase separation between polymeric and small molecular components results in devices with efficiencies of about 47 cd/A at a luminance of 1000 cd/m(2). Investigation of OLED degradation demonstrates the presence of two time regimes: one fast component that leads to a strong decrease at short times followed by a slower decrease at longer times. Unlike the long time degradation, the efficiency loss that occurs at short times is reversible and can be recovered by annealing of the device at 180 degrees C. We also show that the long-time degradation must be related to a change of the optical and electrical bulk properties. KW - charge transport KW - conducting polymer KW - degradation KW - host-guest systems KW - light-emitting diodes KW - random copolymer KW - synthesis KW - UV-vis spectroscopy Y1 - 2013 U6 - https://doi.org/10.1002/pola.26409 SN - 0887-624X VL - 51 IS - 3 SP - 601 EP - 613 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Cheng, Lisa Lai-Shen A1 - Vicente, Luis T1 - Verb doubling in Mandarin Chinese JF - Journal of East Asian linguistics N2 - This article examines two so-far-understudied verb doubling constructions in Mandarin Chinese, viz., verb doubling clefts and verb doubling lianaEuro broken vertical bar dou. We show that these constructions have the same internal syntax as regular clefts and lianaEuro broken vertical bar dou sentences, the doubling effect being epiphenomenal; therefore, we classify them as subtypes of the general cleft and lianaEuro broken vertical bar dou constructions, respectively, rather than as independent constructions. Additionally, we also show that, as in many other languages with comparable constructions, the two instances of the verb are part of a single movement chain, which has the peculiarity of allowing Spell-Out of more than one link. KW - Mandarin Chinese KW - Verb doubling KW - Verb movement KW - Cleft KW - lian ... dou Y1 - 2013 U6 - https://doi.org/10.1007/s10831-012-9095-6 SN - 0925-8558 VL - 22 IS - 1 SP - 1 EP - 37 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Niemeyer, Helen A1 - Musch, Jochen A1 - Pietrowsky, Reinhard T1 - Publication Bias in meta-analyses of the efficacy of psychotherapeutic interventions for depression JF - Journal of consulting and clinical psychology N2 - Objective: The aim of this study was to assess whether systematic reviews investigating psychotherapeutic interventions for depression are affected by publication bias. Only homogeneous data sets were included, as heterogeneous data sets can distort statistical tests of publication bias. Method: We applied Begg and Mazumdar's adjusted rank correlation test, Egger's regression analysis, and the trim and fill procedure to assess the presence and magnitude of publication bias in all homogeneous data sets of systematic reviews published up to September 2010. Results: Thirty-one data sets reported in 19 meta-analyses fulfilled our inclusion criteria. Significant bias was detected in 5 (16.13%; rank correlation test) and 6 (19.35%; Egger's regression analysis) of these data sets. Applying the trim and fill procedure to amend presumably missing studies rarely changed the assessment of the efficacy of therapeutic interventions, with 2 exceptions. In 1 data set psychotherapy was no longer found to be significantly more efficacious than pharmacotherapy in reducing dropout at posttreatment when publication bias was taken into account. In the 2nd data set, after correcting for publication bias, there was no longer evidence that depressed patients without comorbid personality disorder profited more from psychotherapy and pharmacotherapy than patients with comorbid personality disorder. Conclusions: The results suggest that taken together, psychotherapy research for depression is only marginally affected by the selective reporting of positive outcomes. With 2 notable exceptions, correcting for publication bias did not change the evaluation of the efficacy of psychotherapeutic interventions. KW - depression KW - publication bias KW - meta-analysis KW - psychotherapy research Y1 - 2013 U6 - https://doi.org/10.1037/a0031152 SN - 0022-006X VL - 81 IS - 1 SP - 58 EP - 74 PB - American Psychological Association CY - Washington ER - TY - JOUR A1 - van Leeuwen, Judith A1 - Kern, Kristine T1 - The External Dimension of European Union Marine Governance: Institutional Interplay between the EU and the International Maritime Organization JF - Global environmental politics N2 - This article focuses on the emergence of a decentralized institutional complex, interplay management, and the institutional interplay between the International Maritime Organization (IMO) and the EU in the issue area of environmental shipping policies. It shows that the synergistic relationship between both institutions has been driven primarily by commitment and compliance mechanisms. By influencing IMO decision-making and improving the implementation and effectiveness of IMO conventions, the EU has become a driving force in international environmental shipping policies, and its new initiatives may even enhance its leadership role within the IMO in the future. Despite the still-existing lack of cognitive leadership by the EU, the synergies between both institutions provide evidence for the EU's leadership capacities in global environmental politics. Y1 - 2013 U6 - https://doi.org/10.1162/GLEP_a_00154 SN - 1526-3800 SN - 1536-0091 VL - 13 IS - 1 SP - 69 EP - + PB - MIT Press CY - Cambridge ER -