TY  - GEN
A1  - Prinz, Julia
A1  - Heck, Christian
A1  - Ellerik, Lisa
A1  - Merk, Virginia
A1  - Bald, Ilko
T1  - DNA origami based Au–Ag-core–shell nanoparticle dimers with single-molecule SERS sensitivity
N2  - DNA origami nanostructures are a versatile tool to arrange metal nanostructures and other chemical entities with nanometer precision. In this way gold nanoparticle dimers with defined distance can be constructed, which can be exploited as novel substrates for surface enhanced Raman scattering (SERS). We have optimized the size, composition and arrangement of Au/Ag nanoparticles to create intense SERS hot spots, with Raman enhancement up to 1010, which is sufficient to detect single molecules by Raman scattering. This is demonstrated using single dye molecules (TAMRA and Cy3) placed into the center of the nanoparticle dimers. In conjunction with the DNA origami nanostructures novel SERS substrates are created, which can in the future be applied to the SERS analysis of more complex biomolecular targets, whose position and conformation within the SERS hot spot can be precisely controlled.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 221 
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-89714
SP  - 5612
EP  - 5620
ER  - 
TY  - JOUR
A1  - Prinz, Julia
A1  - Heck, Christian
A1  - Ellerik, Lisa
A1  - Merk, Virginia
A1  - Bald, Ilko
T1  - DNA origami based Au-Ag-core-shell nanoparticle dimers with single-molecule SERS sensitivity
JF  - Nanoscale
N2  - DNA origami nanostructures are a versatile tool to arrange metal nanostructures and other chemical entities with nanometer precision. In this way gold nanoparticle dimers with defined distance can be constructed, which can be exploited as novel substrates for surface enhanced Raman scattering (SERS). We have optimized the size, composition and arrangement of Au/Ag nanoparticles to create intense SERS hot spots, with Raman enhancement up to 10(10), which is sufficient to detect single molecules by Raman scattering. This is demonstrated using single dye molecules (TAMRA and Cy3) placed into the center of the nanoparticle dimers. In conjunction with the DNA origami nanostructures novel SERS substrates are created, which can in the future be applied to the SERS analysis of more complex biomolecular targets, whose position and conformation within the SERS hot spot can be precisely controlled.
Y1  - 2016
U6  - https://doi.org/10.1039/c5nr08674d
SN  - 2040-3364
SN  - 2040-3372
VL  - 8
SP  - 5612
EP  - 5620
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Prinz, Julia
A1  - Heck, Christian
A1  - Ellerik, Lisa
A1  - Merk, Virginia
A1  - Bald, Ilko
T1  - DNA origami based Au–Ag-core–shell nanoparticle dimers with single-molecule SERS sensitivity
JF  - Nanoscale
N2  - DNA origami nanostructures are a versatile tool to arrange metal nanostructures and other chemical entities with nanometer precision. In this way gold nanoparticle dimers with defined distance can be constructed, which can be exploited as novel substrates for surface enhanced Raman scattering (SERS). We have optimized the size, composition and arrangement of Au/Ag nanoparticles to create intense SERS hot spots, with Raman enhancement up to 1010, which is sufficient to detect single molecules by Raman scattering. This is demonstrated using single dye molecules (TAMRA and Cy3) placed into the center of the nanoparticle dimers. In conjunction with the DNA origami nanostructures novel SERS substrates are created, which can in the future be applied to the SERS analysis of more complex biomolecular targets, whose position and conformation within the SERS hot spot can be precisely controlled.
Y1  - 2016
U6  - https://doi.org/10.1039/C5NR08674D
IS  - 8
SP  - 5612
EP  - 5620
PB  - RSC Publishing
CY  - Cambridge
ER  -