TY - GEN A1 - Laubrock, Jochen A1 - Engbert, Ralf A1 - Cajar, Anke T1 - Gaze-contingent manipulation of the FVF demonstrates the importance of fixation duration for explaining search behavior T2 - Behavioral and brain sciences : an international journal of current research and theory with open peer commentary N2 - Hulleman & Olivers' (H&O's) model introduces variation of the functional visual field (FVF) for explaining visual search behavior. Our research shows how the FVF can be studied using gaze-contingent displays and how FVF variation can be implemented in models of gaze control. Contrary to H&O, we believe that fixation duration is an important factor when modeling visual search behavior. Y1 - 2017 U6 - https://doi.org/10.1017/S0140525X16000145 SN - 0140-525X SN - 1469-1825 VL - 40 SP - 31 EP - 32 PB - Cambridge Univ. Press CY - New York ER - TY - JOUR A1 - Hörmann, Simon A1 - dos Santos, Luara Ferreira A1 - Morkisch, Nadine A1 - Jettkowski, Katrin A1 - Sillis, Moran A1 - Devan, Hemakumar A1 - Kanagasabai, Parimala S. A1 - Schmidt, Henning A1 - Krüger, Jörg A1 - Dohle, Christian A1 - Regenbrecht, Holger A1 - Hale, Leigh A1 - Cutfield, Nicholas J. T1 - Computerised mirror therapy with Augmented Reflection Technology for early stroke rehabilitation BT - clinical feasibility and integration as an adjunct therapy JF - Disability and rehabilitation : an international, multidisciplinary journal N2 - Purpose: New rehabilitation strategies for post-stroke upper limb rehabilitation employing visual stimulation show promising results, however, cost-efficient and clinically feasible ways to provide these interventions are still lacking. An integral step is to translate recent technological advances, such as in virtual and augmented reality, into therapeutic practice to improve outcomes for patients. This requires research on the adaptation of the technology for clinical use as well as on the appropriate guidelines and protocols for sustainable integration into therapeutic routines. Here, we present and evaluate a novel and affordable augmented reality system (Augmented Reflection Technology, ART) in combination with a validated mirror therapy protocol for upper limb rehabilitation after stroke. Results: The results showed that the combination and application of the Berlin Protocol for Mirror Therapy together with ART was feasible for clinical use. This combination was integrated into the therapeutic plan of subacute stroke patients at the two clinical locations where the second part of this research was conducted. Conclusions: Our findings pave the way for using technology to provide mirror therapy in clinical settings and show potential for the more effective use of inpatient time and enhanced recoveries for patients. IMPLICATIONS FOR REHABILITATION Computerised Mirror Therapy is feasible for clinical use Augmented Reflection Technology can be integrated as an adjunctive therapeutic intervention for subacute stroke patients in an inpatient setting Virtual Rehabilitation devices such as Augmented Reflection Technology have considerable potential to enhance stroke rehabilitation KW - Augmented reality KW - virtual reality KW - usability KW - user experience KW - upper limb KW - visual illusion Y1 - 2017 U6 - https://doi.org/10.1080/09638288.2017.1291765 SN - 0963-8288 SN - 1464-5165 VL - 39 SP - 1503 EP - 1514 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Falk, Thomas A1 - Kirk, Michael A1 - Lohmann, Dirk A1 - Kruger, Bertus A1 - Hüttich, Christian A1 - Kamukuenjandje, Richard T1 - The profits of excludability and transferability in redistributive land reform in central Namibia JF - Development Southern Africa N2 - Policies which redistribute property rights to land can improve the well-being of rural households and can have overall growth effects. In many cases, however, land reforms are driven mainly by politically justified objectives. Under such circumstances, little emphasis is placed on whether and, if so, how property rights can increase productivity. Following 18 years of land reform implementation in Namibia, we evaluated 65 beneficiaries in Namibia. We assess to which degree land rights affects their farm income. The study focuses on Namibia’s two main commercial land reform instruments, namely the Farm Unit Resettlement Scheme and the Affirmative Action Loan Scheme. We find evidence that the majority of land reform projects are not profitable. Further, our study confirms the importance of the right to restrict land access compared with the right to transfer. The long-term leasehold contract seemingly provides sufficient incentives to make productive use of the land. KW - Redistributive land reform KW - property rights KW - farm productivity KW - pastoralism KW - Namibia Y1 - 2017 U6 - https://doi.org/10.1080/0376835X.2016.1269633 SN - 0376-835X SN - 1470-3637 VL - 34 SP - 314 EP - 329 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - McElvenny, James T1 - Grammar, typology and the Humboldtian tradition in the work of Georg von der Gabelentz JF - Language & history : journal of the Henry Sweet Society for the History of Linguistic Ideas N2 - A frequently mentioned if somewhat peripheral figure in the historiography of late nineteenth-century linguistics is the German sinologist and general linguist Georg von der Gabelentz (1840–1893). Today Gabelentz is chiefly remembered for several insights that proved to be productive in the development of subsequent schools and subdisciplines. In this paper, we examine two of these insights, his analytic and synthetic systems of grammar and his foundational work on typology. We show how they were intimately connected within his conception of linguistic research, and how this was in turn embedded in the tradition established by Wilhelm von Humboldt (1767–1835), especially as it was further developed by H. Steinthal (1823–1899). This paper goes beyond several previous works with a similar focus by drawing on a wider range of Gabelentz’ writings, including manuscript sources that have only recently been published, and by examining specific textual connections between Gabelentz and his predecessors. KW - History of linguistics KW - typology KW - language description KW - grammar KW - Humboldtian linguistics KW - Georg von der Gabelentz KW - H . Steinthal KW - Wilhelm von Humboldt Y1 - 2017 U6 - https://doi.org/10.1080/17597536.2016.1212580 SN - 1759-7536 SN - 1759-7544 VL - 60 SP - 1 EP - 20 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Prieto, Julio T1 - From blind shorthand T1 - de la ciega taquigrafía BT - the elusive erudition of Luis Chitarroni BT - la elusiva erudición de Luis Chitarroni JF - Cahiers de LIRICO N2 - This essay explores the poetics of obscurity that informs Luis Chitarroni’s « unfinished novel » The No Variations. Focusing on the « reticent » erudition that distinguishes this text, my analysis examines its dialogue with the paradigm of Borges’ erudition and narrative poetics, as well as with certain « counter-Borgesian » constellations in recent Argentine literature. My reading aims to show how Chitarroni’s anti-novel reactivates a specific Argentinean tradition of productive illegibility while considering how it relates to the practices of « impediment » and « aesthetic reduction » that pervade modern art and literature. N2 - Este ensayo explora la poética de la opacidad en la escritura de Luis Chitarroni y en particular en su « novela inconclusa » Peripecias del no. El análisis se enfoca en la erudición « denegante » que distingue a este texto, y en su diálogo con el modelo de la erudición borgiana y con su poética narrativa, así como con una serie de líneas « contraborgianas » en la literatura argentina reciente. Mi lectura se orienta a mostrar cómo la anti-novela de Chitarroni reactiva una específica tradición literaria argentina de poéticas de lo ilegible a la vez que enlaza con las prácticas del « impedimento » y de la « reducción estética » que recorren la modernidad artística y literaria. N2 - Cet article explore la poétique de la opacité mise en jeu par Luis Chitarroni dans son « roman inachevé » Aventures du Non. À partir d’une analyse de l’érudition « reticente » inhérente à ce texte, j’examine le dialogue que Chitarroni établit avec le modèle de l’érudition borgésienne et sa poétique du récit, ainsi qu’avec une série de lignes narratives « post-borgésiennes » dans la littérature argentine récente. Ma lecture vise à montrer comment l’« anti-roman » de Chitarroni réactive une particulière tradition littéraire argentine relative aux poétiques de l’illisible tout en se liant à la fois avec les pratiques de l’« empêchement » narratif et de la « réduction esthétique » qui traversent la modernité artistique et littéraire. KW - poetics of the illegible KW - hermeticism KW - Chitarroni KW - Borges KW - modern art Y1 - 2017 UR - http://journals.openedition.org/lirico/3807 U6 - https://doi.org/10.4000/lirico.3807 SN - 2263-2158 SN - 2262-8339 PB - Universität de Paris CY - Saint-Denis ER - TY - GEN A1 - Fabian, Benjamin A1 - Baumann, Annika A1 - Ehlert, Mathias A1 - Ververis, Vasilis A1 - Ermakova, Tatiana T1 - CORIA - Analyzing internet connectivity risks using network graphs T2 - 2017 IEEE International Conference on Communications (ICC) N2 - The Internet can be considered as the most important infrastructure for modern society and businesses. A loss of Internet connectivity has strong negative financial impacts for businesses and economies. Therefore, assessing Internet connectivity, in particular beyond their own premises and area of direct control, is of growing importance in the face of potential failures, accidents, and malicious attacks. This paper presents CORIA, a software framework for an easy analysis of connectivity risks based on large network graphs. It provides researchers, risk analysts, network managers and security consultants with a tool to assess an organization's connectivity and paths options through the Internet backbone, including a user-friendly and insightful visual representation of results. CORIA is flexibly extensible in terms of novel data sets, graph metrics, and risk scores that enable further use cases. The performance of CORIA is evaluated by several experiments on the Internet graph and further randomly generated networks. KW - risk analysis KW - connectivity KW - graph analysis KW - complex networks KW - Internet Y1 - 2017 SN - 978-1-4673-8999-0 SN - 978-1-4673-9000-2 U6 - https://doi.org/10.1109/ICC.2017.7996828 SN - 1550-3607 PB - IEEE CY - Piscataway ER - TY - GEN A1 - Grossi, Giuseppe A1 - Reichard, Christoph A1 - Thomasson, Anna A1 - Vakkuri, Jarmo T1 - Editorial T2 - Public money & management : integrating theory and practice in public management Y1 - 2017 U6 - https://doi.org/10.1080/09540962.2017.1344007 SN - 0954-0962 SN - 1467-9302 VL - 37 SP - 379 EP - 386 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - GEN A1 - Hass, Roland A1 - Sandmann, Michael A1 - Reich, Oliver T1 - Photonic sensing in highly concentrated biotechnical processes by photon density wave spectroscopy T2 - Proceedings SPIE 10323, 25th International Conference on Optical Fiber Sensors N2 - Photon Density Wave (PDW) spectroscopy is introduced as a new approach for photonic sensing in highly concentrated biotechnical processes. It independently quantifies the absorption and reduced scattering coefficient calibration-free and as a function of time, thus describing the optical properties in the vis/NIR range of the biomaterial during their processing. As examples of industrial relevance, enzymatic milk coagulation, beer mashing, and algae cultivation in photo bioreactors are discussed. KW - Photon Density Wave Spectroscopy KW - multiple light scattering KW - fermentation KW - algae cultivation KW - process analytical technology KW - fiber spectroscopy Y1 - 2017 SN - 978-1-5090-4850-2 U6 - https://doi.org/10.1117/12.2263617 SN - 0277-786X SN - 1996-756X VL - 10323 PB - IEEE CY - New York ER - TY - JOUR A1 - Schmidt, Marco F. T1 - miRNA Targeting Drugs BT - the next blockbusters? JF - Drug Target miRNA: Methods and Protocols N2 - Only 20 years after the discovery of small non-coding, single-stranded ribonucleic acids, so-called microRNAs (miRNAs), as post-transcriptional gene regulators, the first miRNA-targeting drug Miravirsen for the treatment of hepatitis C has been successfully tested in clinical Phase II trials. Addressing miRNAs as drug targets may enable the cure, or at least the treatment of diseases, which presently seems impossible. However, due to miRNAs’ chemical structure, generation of potential drug molecules with necessary pharmacokinetic properties is still challenging and requires a re-thinking of the drug discovery process. Therefore, this chapter highlights the potential of miRNAs as drug targets, discusses the challenges, and tries to give a complete overview of recent strategies in miRNA drug discovery. KW - miRNA KW - Drug discovery KW - microRNA-induced silencing complex KW - Antisense agents KW - Small-molecule miRNA modulators KW - Argonaute 2 protein Y1 - 2016 SN - 978-1-4939-6563-2 SN - 978-1-4939-6561-8 U6 - https://doi.org/10.1007/978-1-4939-6563-2_1 SN - 1064-3745 SN - 1940-6029 VL - 1517 SP - 3 EP - 22 PB - Springer CY - New York ER - TY - JOUR A1 - Atilaw, Yoseph A1 - Duffy, Sandra A1 - Heydenreich, Matthias A1 - Muiva-Mutisya, Lois A1 - Avery, Vicky M. A1 - Erdelyi, Mate A1 - Yenesew, Abiy T1 - Three Chalconoids and a Pterocarpene from the Roots of Tephrosia aequilata JF - Molecules N2 - In our search for new antiplasmodial agents, the CH2Cl2/CH3OH (1:1) extract of the roots of Tephrosia aequilata was investigated, and observed to cause 100% mortality of the chloroquine-sensitive (3D7) strain of Plasmodium falciparum at a 10 mg/mL concentration. From this extract three new chalconoids, E-2,6-dimethoxy-3,4-(2,2-dimethyl)pyranoretrochalcone (1, aequichalcone A), Z-2,6-dimethoxy-3,4-(2,2-dimethyl)pyranoretrochalcone (2, aequichalcone B), 4-ethoxy-3-hydroxypraecansone B (3, aequichalcone C) and a new pterocarpene, 3,4:8,9-dimethylenedioxy-6a,11a-pterocarpene (4), along with seven known compounds were isolated. The purified compounds were characterized by NMR spectroscopic and mass spectrometric analyses. Compound 1 slowly converts into 2 in solution, and thus the latter may have been enriched, or formed, during the extraction and separation process. The isomeric compounds 1 and 2 were both observed in the crude extract. Some of the isolated constituents showed good to moderate antiplasmodial activity against the chloroquine-sensitive (3D7) strain of Plasmodium falciparum. KW - Tephrosia aequilata KW - chalcone KW - retrochalcone KW - aequichalcone A KW - aequichalcone B KW - aequichalcone C KW - pterocarpene KW - antiplasmodial Y1 - 2017 U6 - https://doi.org/10.3390/molecules22020318 SN - 1420-3049 VL - 22 IS - 2 PB - MDPI CY - Basel ER -