TY - JOUR A1 - Kroeller, Katja A1 - Warschburger, Petra T1 - Problematic eating behavior in childhood do maternal feeding patterns play a role? JF - Praxis der Kinderpsychologie und Kinderpsychiatrie : Ergebnisse aus Psychotherapie, Beratung und Psychiatrie N2 - Past research indicates an association in adults and young people of emotional and contextual factors with a higher risk for the development of eating disorders or obesity. Few studies focus on problematic eating patterns in childhood, especially in association with parental feeding strategies. 482 mothers completed a questionnaire about eating behaviors and the weight status of their 1- to 10-year-old child as well as their own feeding strategies. A classification of the child's eating behavior (food responsiveness, emotional eating, external eating, eating time and meal structure) using hierarchical cluster analysis revealed a conspicuous eating pattern (10 %) showing above-average values in all eating behaviors. Controlling for weight and demographic variables mothers of children with conspicuous eating patterns were characterized by restrictive strategies and were less likely to encourage or facilitate their child to control his or her eating. Similar problematic eating patterns were also identified in early childhood. The association of maternal feeding strategies - beyond weight control issues - with conspicuous eating patterns in children might indicate a possibility of early prevention through parent training. KW - child's eating behavior KW - problematic eating behavior KW - maternal feeding behavior KW - obesity Y1 - 2011 SN - 0032-7034 VL - 60 IS - 4 SP - 253 EP - 269 PB - Vandenhoeck & Ruprecht CY - Göttingen ER - TY - INPR A1 - Warschburger, Petra A1 - Lehmkuhl, Ulrike T1 - Disturbed eating behavior and its consequences T2 - Praxis der Kinderpsychologie und Kinderpsychiatrie : Ergebnisse aus Psychotherapie, Beratung und Psychiatrie Y1 - 2011 SN - 0032-7034 VL - 60 IS - 4 SP - 249 EP - 252 PB - Vandenhoeck & Ruprecht CY - Göttingen ER - TY - JOUR A1 - Buller, Jens A1 - Laschewsky, André A1 - Lutz, Jean-Francois A1 - Wischerhoff, Erik T1 - Tuning the lower critical solution temperature of thermoresponsive polymers by biospecific recognition JF - Polymer Chemistry N2 - A thermosensitive statistical copolymer based on oligo(ethylene glycol) methacrylates incorporating biotin was synthesized by free radical copolymerisation. The influence of added avidin on its thermoresponsive behaviour was investigated. The specific binding of avidin to the biotinylated copolymers provoked a marked increase of the lower critical solution temperature. Y1 - 2011 U6 - https://doi.org/10.1039/c1py00001b SN - 1759-9954 VL - 2 IS - 7 SP - 1486 EP - 1489 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Zehm, Daniel A1 - Laschewsky, André A1 - Heunemann, Peggy A1 - Gradzielski, Michael A1 - Prevost, Sylvain A1 - Liang, Hua A1 - Rabe, Jürgen P. A1 - Lutz, Jean-Francois T1 - Synthesis and self-assembly of amphiphilic semi-brush and dual brush block copolymers in solution and on surfaces JF - Polymer Chemistry N2 - The combination of two techniques of controlled free radical polymerization, namely the reversible addition fragmentation chain transfer (RAFT) and the atom transfer radical polymerization (ATRP) techniques, together with the use of a macromonomer allowed the synthesis of symmetrical triblock copolymers, designed as amphiphilic dual brushes. One type of brush was made of poly(n-butyl acrylate) as soft hydrophobic block, i.e. characterized by a low glass transition temperature, while the other one was made of hydrophilic poly(ethylene glycol) (PEG). The new triblock polymers represent "giant surfactants" according to their molecular architecture. The hydrophobic and hydrophilic blocks microphase separate in the bulk. In aqueous solution, they aggregate into globular micellar aggregates, their size being determined by the length of the stretched polymer molecules. As determined by the combination of various scattering techniques for the dual brush copolymer, a rather compact structure is formed, which is dominated by the large hydrophobic poly(n-butyl acrylate) block. The aggregation number for the dual brush is about 10 times larger than for the "semi-brush" precursor copolymer, due to the packing requirements for the much bulkier hydrophobic core. On mica surfaces the triblock copolymers adsorb with worm-like backbones and stretched out side chains. Y1 - 2011 U6 - https://doi.org/10.1039/c0py00200c SN - 1759-9954 VL - 2 IS - 1 SP - 137 EP - 147 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Rohlfing, Anne-Katrin A1 - Miteva, Yana A1 - Moronetti, Lorenza A1 - He, Liping A1 - Lamitina, Todd T1 - The caenorhabditis elegans mucin-like protein OSM-8 negatively regulates osmosensitive physiology via the transmembrane protein PTR-23 JF - PLoS Genetics : a peer-reviewed, open-access journal N2 - The molecular mechanisms of animal cell osmoregulation are poorly understood. Genetic studies of osmoregulation in yeast have identified mucin-like proteins as critical regulators of osmosensitive signaling and gene expression. Whether mucins play similar roles in higher organisms is not known. Here, we show that mutations in the Caenorhabditis elegans mucin-like gene osm-8 specifically disrupt osmoregulatory physiological processes. In osm-8 mutants, normal physiological responses to hypertonic stress, such as the accumulation of organic osmolytes and activation of osmoresponsive gene expression, are constitutively activated. As a result, osm-8 mutants exhibit resistance to normally lethal levels of hypertonic stress and have an osmotic stress resistance (Osr) phenotype. To identify genes required for Osm-8 phenotypes, we performed a genome-wide RNAi osm-8 suppressor screen. After screening,18,000 gene knockdowns, we identified 27 suppressors that specifically affect the constitutive osmosensitive gene expression and Osr phenotypes of osm-8 mutants. We found that one suppressor, the transmembrane protein PTR-23, is co-expressed with osm-8 in the hypodermis and strongly suppresses several Osm-8 phenotypes, including the transcriptional activation of many osmosensitive mRNAs, constitutive glycerol accumulation, and osmotic stress resistance. Our studies are the first to show that an extracellular mucin-like protein plays an important role in animal osmoregulation in a manner that requires the activity of a novel transmembrane protein. Given that mucins and transmembrane proteins play similar roles in yeast osmoregulation, our findings suggest a possible evolutionarily conserved role for the mucin-plasma membrane interface in eukaryotic osmoregulation. Y1 - 2011 U6 - https://doi.org/10.1371/journal.pgen.1001267 SN - 1553-7390 VL - 7 IS - 1 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Pilz, Marco A1 - Parolai, Stefano A1 - Picozzi, Matteo A1 - Zschau, Jochen T1 - Evaluation of proxies for seismic site conditions in large urban areas the example of Santiago de Chile JF - Physics and chemistry of the earth N2 - Characterizing the local site response in large cities is an important step towards seismic hazard assessment. To this regard, single station seismic noise measurements were carried out at 146 sites in the northern part of Santiago de Chile. This extensive survey allowed the fundamental resonance frequency of the sedimentary cover, derived from horizontal-to-vertical (H/V) spectral ratios, to be mapped. By inverting the spectral ratios under the constraint of the thickness of the sedimentary cover, known from previous gravimetric measurements, local S-wave velocity profiles have been retrieved. After interpolation between the individual profiles, the resulting high resolution 3D S-wave velocity model allows the entire area, as well as deeper parts of the basin, to be represented in great detail. Since one lithology shows a great scatter in the velocity values only a very general correlation between S-wave velocity in the uppermost 30 m (v(s)(30)) and local geology is found. Local S-wave velocity profiles can serve as a key factor in seismic hazard assessment, since they allow an estimate of the amplification potential of the sedimentary cover. Mapping the intensity distribution of the 27 February 2010 Maule, Chile, event (Mw = 8.8) the results indicate that local amplification of the ground motion might partially explain the damage distribution and encourage the use of the low cost seismic noise techniques for the study of seismic site effects. KW - Ambient seismic noise KW - H/V ratio KW - Inversion KW - S-wave velocity KW - Site effects Y1 - 2011 U6 - https://doi.org/10.1016/j.pce.2011.01.007 SN - 1474-7065 VL - 36 IS - 16 SP - 1259 EP - 1266 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Utecht, Manuel Martin A1 - Klamroth, Tillmann A1 - Saalfrank, Peter T1 - Optical absorption and excitonic coupling in azobenzenes forming self-assembled monolayers a study based on density functional theory JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - Based on the analysis of optical absorption spectra, it has recently been speculated that the excitonic coupling between individual azobenzene-functionalized alkanethiols arranged in a self-assembled monolayer (SAM) on a gold surface could be strong enough to hinder collective trans-cis isomerization-on top of steric hindrance [Gahl et al., J. Am. Chem. Soc., 2010, 132, 1831]. Using models of SAMs of increasing complexity (dimer, linear N-mers, and two-dimensionally arranged N-mers) and density functional theory on the (TD-) B3LYP/6-31G* level, we determine optical absorption spectra, the nature and magnitude of excitonic couplings, and the corresponding spectral shifts. It is found that at inter-monomer distances of about 20 angstrom and above, TD-B3LYP excitation frequencies (and signal intensities) can be well described by the frequently used point-dipole approximation. Further, calculated blue shifts in optical absorption spectra account for the experimental observations made for azobenzene/gold SAMs, and hint to the fact that they can indeed be responsible for reduced switching probability in densely packed self-assembled structures. Y1 - 2011 U6 - https://doi.org/10.1039/c1cp22793a SN - 1463-9076 VL - 13 IS - 48 SP - 21608 EP - 21614 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Kleinpeter, Erich A1 - Koch, Andreas T1 - Chelatoaromaticity-existing: yes or no? An answer given by spatial magnetic properties (through space NMR shieldings-TSNMRS) JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - The spatial magnetic properties (through space NMR shieldings-TSNMRS) of metal complexes (with ligands such as acetylacetone, 3-hydroxy-pyran(4) one) and "metallobenzenes" have been calculated by the GIAO perturbation method and visualized as Iso-Chemical-Shielding Surfaces (ICSS) of various sizes and directions. The TSNMRS values, thus obtained, can be successfully employed to quantify and visualize partial aromaticity of the metallocyclic ring by comparison with the spatial magnetic properties of the corresponding non-complexed ligands in comparable structural and electronic situations, and benzene, respectively. Because anisotropy/ring current effects in H-1 NMR spectra proved to be the molecular response property of TSNMRS, the results obtained concerning partial "chelatoaromaticity" are experimentally ensured. Y1 - 2011 U6 - https://doi.org/10.1039/c1cp21942a SN - 1463-9076 SN - 1463-9084 VL - 13 IS - 46 SP - 20593 EP - 20601 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Tiseanu, Carmen A1 - Parvulescu, Vasile I. A1 - Boutonnet, Magali A1 - Cojocaru, Bogdan A1 - Primus, Philipp A. A1 - Teodorescu, Cristian M. A1 - Solans, Conchita A1 - Sanchez Dominguez, Margarita T1 - Surface versus volume effects in luminescent ceria nanocrystals synthesized by an oil-in-water microemulsion method JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - Pure and europium (Eu3+) doped cerium dioxide (CeO2) nanocrystals have been synthesized by a novel oil-in-water microemulsion reaction method under soft conditions. In-situ X-ray diffraction and RAMAN spectroscopy, high-resolution transmission electron microscopy, UV/Vis diffuse-reflectance and Fourier transform infrared spectroscopy as well as time-resolved photoluminescence spectroscopy were used to characterize the nanaocrystals. The as-synthesized powders are nanocrystalline and have a narrow size distribution centered on 3 nm and high surface area of similar to 250 m(2) g(-1). Only a small fraction of the europium ions substitutes for the bulk, cubic Ce4+ sites in the europium-doped ceria nanocrystals. Upon calcination up to 1000 degrees C, a remarkable high surface area of similar to 120 m(2) g (-1) is preserved whereas an enrichment of the surface Ce4+ relative to Ce3+ ions and relative strong europium emission with a lifetime of similar to 1.8 ms and FWHM as narrow as 10 cm(-1) are measured. Under excitation into the UV and visible spectral range, the europium doped ceria nanocrystals display a variable emission spanning the orange-red wavelengths. The tunable emission is explained by the heterogeneous distribution of the europium dopants within the ceria nanocrystals coupled with the progressive diffusion of the europium ions from the surface to the inner ceria sites and the selective participation of the ceria host to the emission sensitization. Effects of the bulk-doping and impregnation with europium on the ceria host structure and optical properties are also discussed. Y1 - 2011 U6 - https://doi.org/10.1039/c1cp21135h SN - 1463-9076 VL - 13 IS - 38 SP - 17135 EP - 17145 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Thiel, Kerstin A1 - Klamroth, Tillmann A1 - Strauch, Peter A1 - Taubert, Andreas T1 - On the interaction of ascorbic acid and the tetrachlorocuprate ion [CuCl4](2-) in CuCl nanoplatelet formation from an ionic liquid precursor (ILP) JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - The formation of CuCl nanoplatelets from the ionic liquid precursor (ILP) butylpyridinium tetrachlorocuprate [C4Py](2)[CuCl4] using ascorbic acid as a reducing agent was investigated. In particular, electron paramagnetic resonance (EPR) spectroscopy was used to evaluate the interaction between ascorbic acid and the Cu(II) ion before reduction to Cu(I). EPR spectroscopy suggests that the [CuCl4](2-) ion in the neat IL is a distorted tetrahedron, consistent with DFT calculations. Addition of ascorbic acid leads to the removal of one chloride from the [CuCl4](2-) anion, as shown by DFT and the loss of symmetry by EPR. DFT furthermore suggests that the most stable adduct is formed when only one hydroxyl group of the ascorbic acid coordinates to the Cu(II) ion. Y1 - 2011 U6 - https://doi.org/10.1039/c1cp20648f SN - 1463-9076 VL - 13 IS - 30 SP - 13537 EP - 13543 PB - Royal Society of Chemistry CY - Cambridge ER -