TY  - GEN
A1  - Awasthi, Swapnil
A1  - Kaminski, Jakob
A1  - Rapp, Michael A.
A1  - Schlagenhauf, Florian
A1  - Walter, Henrik
A1  - Ruggeri, Barbara
A1  - Ripke, Stephan
A1  - Schumann, Gunter
A1  - Heinz, Andreas
T1  - A neural signature of malleability
BT  - general intelligence correlates with ventral striatal  activation and epigenetic makers of dopamine neurotransmission
T2  - European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
N2  - General intelligence has a substantial genetic background in children, adolescents, and adults, but environmental factors also strongly correlate with cognitive performance as evidenced by a strong (up to one SD) increase in average intelligence test results in the second half of the previous century. This change occurred in a period apparently too short to accommodate radical genetic changes. It is highly suggestive that environmental factors interact with genotype by possible modification of epigenetic factors that regulate gene expression and thus contribute to individual malleability. This modification might as well be reflected in recent observations of an association between dopamine-dependent encoding of reward prediction errors and cognitive capacity, which was modulated by adverse life events.
Y1  - 2019
U6  - https://doi.org/10.1016/j.euroneuro.2017.08.139
SN  - 0924-977X
SN  - 1873-7862
VL  - 29
SP  - S858
EP  - S859
PB  - Elsevier
CY  - Amsterdam
ER  -