TY  - JOUR
A1  - Mariën, Peter
A1  - Abutalebi, Jubin
A1  - Engelborghs, Sebastian
A1  - De Deyn, Peter Paul
T1  - Pathophysiology of language switching and mixing in an early bilingual child with subcortical aphasia
N2  - Acquired aphasia after circumscribed vascular subcortical lesions has not been reported in bilingual children. We report clinical and neuroimaging findings in an early bilingual boy who incurred equally severe transcortical sensory aphasia in his first language (L1) and second language (L2) after a posterior left thalamic hemorrhage. Following recurrent bleeding of the lesion the aphasic symptoms substantially aggravated. Spontaneous pathological language switching and mixing were found in both languages. Remission of these phenomena was reflected on brain perfusion SPECT revealing improved perfusion in the left frontal lobe and left caudate nucleus. The parallelism between the evolution of language symptoms and the SPECT findings may demonstrate that a subcortical left frontal lobe circuity is crucially involved in language switching and mixing
Y1  - 2005
ER  -