TY - JOUR A1 - Mell, Thomas A1 - Heekeren, Hauke R. A1 - Marschner, Alexander A1 - Wartenburger, Isabell A1 - Villringer, Arno A1 - Reischies, Friedel M. T1 - Effect of aging on stimulus-reward association learning N2 - The flexible learning of stimulus-reward associations when required by situational context is essential for everyday behavior. Older adults experience a progressive decline in several cognitive functions and show deficiencies in neuropsychological tasks requiring flexible adaptation to external feedback, which could be related to impairments in reward association learning. To study the effect of aging on stimulus-reward association learning 20 young and 20 older adults performed a probabilistic object reversal task (pORT) along with a battery of tests assessing executive functions and general intellectual abilities. The pORT requires learning and reversing associations between actions and their outcomes. Older participants collected fewer points, needed more trials to reach the learning criterion, and completed less blocks successfully compared to young adults. This difference remained statistically significant after correcting for the age effect of other tests assessing executive functions. This suggests that there is an age-related difference in reward association learning as measured using the pORT, which is not closely related to other executive functions with respect to the age effect. In human aging, structural alterations of reward detecting structures and functional changes of the dopaminergic as well as the serotonergic system might contribute to the deficit in reward association learning observed in this study. (C) 2004 Elsevier Ltd. All rights reserved Y1 - 2005 SN - 0028-3932 ER - TY - JOUR A1 - Marschner, Alexander A1 - Mell, Thomas A1 - Wartenburger, Isabell A1 - Villringer, Arno A1 - Reischies, Friedel M. A1 - Heekeren, Hauke R. T1 - Reward-based decision-making and aging Y1 - 2005 SN - 0361-9230 ER -