TY - JOUR A1 - Hlinak, Andreas A1 - Müller, Thomas A1 - Kramer, Matthias A1 - Mühle, Ralf-Udo A1 - Liebherr, Helga A1 - Ziedler, Klaus T1 - A descriptive analysis of the potenrial association between migration patterns of bean and white-fronted geese and the occurence of newcastle disease outbreaks in domestic birds N2 - Sightings and migration patterns of 65 bean and 65 white-fronted geese are reported. These geese were tagged and serologically screened. 19 of the 53 birds sighted had serologic evidence of Newcastle Disease. The migration patterns of the wild geese provided further evidence that the main resting and wintering sites of migratory waterfowl are likely to be important for the inter- and intraspecies transmission of avian diseases. Y1 - 1999 SN - 0005-2086 ER - TY - JOUR A1 - Hlinak, Andreas A1 - Mühle, Ralf-Udo A1 - Werner, Ortrud A1 - Globig, Anja A1 - Starick, Elke A1 - Schirrmeier, Horst A1 - Hoffmann, Bernd A1 - Engelhardt, Andreas A1 - Hübner, Dagmar A1 - Conraths, Franz J. A1 - Wallschläger, Hans-Dieter A1 - Kruckenberg, Helmut A1 - Müller, Thomas T1 - A virological survey in migrating waders and other waterfowl in one of the most important resting sites of Germany N2 - Wild birds are considered a potential reservoir or a carrier of viral diseases and may therefore play a role in the epidemiology of economically important or zoonotic diseases. In 2001 and 2002, a survey with special emphasis oil virus isolation in migrating waders and some other birds were conducted. In one of the most important inland resting sites for migratory waterfowl, tracheal and cloacal swabs were collected from 465 waders representing 19 different species, and 165 other birds that were not captured on purpose. A total of 42 avian viruses were isolated, 34 of these were identified as paramyxoviruses (PMVs). The majority of isolates came from waders and wild ducks, and were characterized as PMV-1. In contrast, PMV-4 was found in wild ducks only, PMV-6 was mainly detected in wader species. Four avian influenza viruses (ATVs), belonging to H4 and H3 haemagglutinin subtype, were isolated from wild duck species. Furthermore, four reo-like viruses were isolated from one particular wader species for the first time. The majority of virus positive birds were < 1 year old and did not show any clinical symptoms. There was no evidence for the presence of West Nile virus in these birds. These results confirm that the restricted resting sites in Western Europe must be considered as important locations for the intra- and interspecies transmission of avian viruses Y1 - 2006 SN - 0931-1793 ER - TY - JOUR A1 - Schatz, Juliane A1 - Freuling, Conrad Martin A1 - Auer, Ernst A1 - Goharriz, Hooman A1 - Harbusch, Christine A1 - Johnson, Nicholas A1 - Kaipf, Ingrid A1 - Mettenleiter, Thomas Christoph A1 - Muehldorder, Kristin A1 - Muehle, Ralf-Udo A1 - Ohlendorf, Bernd A1 - Pott-Dörfer, Bärbel A1 - Prueger, Julia A1 - Ali, Hanan Sheikh A1 - Stiefel, Dagmar A1 - Teubner, Jens A1 - Ulrich, Rainer Günter A1 - Wibbelt, Gudrun A1 - Müller, Thomas T1 - Enhanced passive bat rabies surveillance in indigenous bat species from Germany - A retrospective study JF - PLoS neglected tropical diseases N2 - In Germany, rabies in bats is a notifiable zoonotic disease, which is caused by European bat lyssaviruses type 1 and 2 (EBLV-1 and 2), and the recently discovered new lyssavirus species Bokeloh bat lyssavirus (BBLV). As the understanding of bat rabies in insectivorous bat species is limited, in addition to routine bat rabies diagnosis, an enhanced passive surveillance study, i.e. the retrospective investigation of dead bats that had not been tested for rabies, was initiated in 1998 to study the distribution, abundance and epidemiology of lyssavirus infections in bats from Germany. A total number of 5478 individuals representing 21 bat species within two families were included in this study. The Noctule bat (Nyctalus noctula) and the Common pipistrelle (Pipistrellus pipistrellus) represented the most specimens submitted. Of all investigated bats, 1.17% tested positive for lyssaviruses using the fluorescent antibody test (FAT). The vast majority of positive cases was identified as EBLV-1, predominately associated with the Serotine bat (Eptesicus serotinus). However, rabies cases in other species, i.e. Nathusius' pipistrelle bat (Pipistrellus nathusii), P. pipistrellus and Brown long-eared bat (Plecotus auritus) were also characterized as EBLV-1. In contrast, EBLV-2 was isolated from three Daubenton's bats (Myotis daubentonii). These three cases contribute significantly to the understanding of EBLV-2 infections in Germany as only one case had been reported prior to this study. This enhanced passive surveillance indicated that besides known reservoir species, further bat species are affected by lyssavirus infections. Given the increasing diversity of lyssaviruses and bats as reservoir host species worldwide, lyssavirus positive specimens, i.e. both bat and virus need to be confirmed by molecular techniques. Y1 - 2014 U6 - https://doi.org/10.1371/journal.pntd.0002835 SN - 1935-2735 VL - 8 IS - 5 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Jeltsch, Florian A1 - Bonte, Dries A1 - Peer, Guy A1 - Reineking, Björn A1 - Leimgruber, Peter A1 - Balkenhol, Niko A1 - Schröder-Esselbach, Boris A1 - Buchmann, Carsten M. A1 - Müller, Thomas A1 - Blaum, Niels A1 - Zurell, Damaris A1 - Böhning-Gaese, Katrin A1 - Wiegand, Thorsten A1 - Eccard, Jana A1 - Hofer, Heribert A1 - Reeg, Jette A1 - Eggers, Ute A1 - Bauer, Silke T1 - Integrating movement ecology with biodiversity research - exploring new avenues to address spatiotemporal biodiversity dynamics Y1 - 2013 UR - http://download.springer.com/static/pdf/827/art%253A10.1186%252F2051-3933-1- 6.pdf?auth66=1394891271_f1a4cb74d6be42ee3f8872ef2ca22c24&ext=.pdf U6 - https://doi.org/10.1186/2051-3933-1-6 ER - TY - JOUR A1 - Holdt, Hans-Jürgen A1 - Müller, Holger A1 - Kelling, Alexandra A1 - Drexler, Hans-Joachim A1 - Müller, Thomas A1 - Schwarze, Thomas A1 - Schilde, Uwe A1 - Starke, Ines T1 - Mercury(II) chloride and iodide complexes of dithia- and tetrathiacrown ethers N2 - The complexes [(HgCl2)(2)((ch)(2)30S(4)O(6))] (1), [HgCl,(mn21S(2)O(5))] (2), [HgCl2(ch18S(2)O(4))] (3) and [HgI(meb12S(2)O(2))](2)[Hg2I6] (4) have been synthesized, characterized and their crystal structures were determined. In [(HgCl2)(2)((ch)(2)3OS(4)O(6))] two HgCl2 units are discretely bonded within the ligand cavity of the 30-membered dichinoxaline-tetrathia-30-crown-10 ((ch)(2)30S(4)O(6)) forming a binuclear complex. HgCl2 forms I : I "in-cavity" complexes with the 21-membered maleonitrile-dithia-21-crown-7(mn21S(2)O(5)) ligand and the 18-membered chinoxaline- dithia-18-crown-6 (ch18S(2)O(4)) ligand, respectively. The 12-membered 4-methyl-benzo-dithia-12-crown-4 (meb12S(2)O(2)) ligand gave with two equivalents HgI2 the compound [HgI(meb12S(2)O(2))](2)[Hg2I6]. In the cation [HgI(meb12S(2)O(2))](+) meb12S(2)O(2) forms with the cation HgI+ a half-sandwich complex Y1 - 2006 UR - http://www3.interscience.wiley.com/cgi-bin/jhome/10005159 U6 - https://doi.org/10.1002/zaac.200500281 SN - 0044-2313 ER - TY - JOUR A1 - Kruckenberg, Helmut A1 - Müller, Thomas A1 - Freuling, Conrad A1 - Mühle, Ralf-Udo A1 - Globig, Anja A1 - Schirrmeier, Horst A1 - Buss, Melanie A1 - Harder, Timm A1 - Kramer, Matthias A1 - Teske, Kathrin A1 - Polderdijk, Kees A1 - Wallschläger, Hans-Dieter A1 - Hlinak, Andreas T1 - Serological and virological survey and resighting of marked wild geese in Germany JF - European journal of wildlife research N2 - In order to investigate the potential role of arctic geese in the epidemiology, the spatial and temporal spread of selected avian diseases, in autumn 2002, a virological and serological survey designed as capture-mark-resighting study was conducted in one of the most important coastal resting sites for migratory waterfowl in Germany. Orophatyngeal, cloacal swabs and blood samples were collected from a total of 147 birds comprising of three different arctic geese species including White-fronted Goose (Anser albifrons), Tundra Bean Goose (Anser fabalis rossicus), Pink-footed Goose (Anser brachyrhynchus) as well as from 29 non-migratory Canada Geese (Branta canadensis). Altogether, six adeno-like viruses (ALV; 95% CI, 1.74-9.92%) and two avian paramyxoviruses (APMV-4; 95% Cl, 0.19-5.53%) were isolated mainly from juvenile White-fronted Geese. In addition, four Canada Geese were infected with lentogenic APMV-1 (95% CI, 3.89-31.66%) at the date of sampling. No avian influenza viruses, reo-like viruses could be isolated despite serological evidence. Likewise, no evidence of current or previous infection by West Nile virus was found. Of the 147 birds tagged in the following years, 137 birds were resighted between 2002 and 2008 accumulating to 1925 sightings. About 90% of all sightings were reported from the main wintering and resting sites in Germany and The Netherlands. Eight of the resighted geese were virus positive (ALV and APMV-4) at the time point of sampling in 2002. KW - Wild geese KW - Anser albifrons KW - White-fronted goose KW - Disease KW - Spatial distribution KW - Winter KW - Distribution KW - Branta canadensis KW - Canada goose KW - Virus KW - Infection KW - Neckbanding Y1 - 2011 U6 - https://doi.org/10.1007/s10344-011-0514-1 SN - 1612-4642 VL - 57 IS - 5 SP - 1025 EP - 1032 PB - Springer CY - New York ER - TY - JOUR A1 - Hlinak, Andreas A1 - Müller, Thomas A1 - Kramer, Matthias A1 - Mühle, Ralf-Udo A1 - Liebherr, Helga A1 - Ziedler, Klaus T1 - Serological survey of viral pathogens in bean and white-fronted geese from Germany Y1 - 1998 SN - 0090-3558 ER - TY - JOUR A1 - Schwarze, Thomas A1 - Sperlich, Eric A1 - Müller, Thomas A1 - Kelling, Alexandra A1 - Holdt, Hans-Jürgen T1 - Synthesis efforts of acyclic bis(monoalkylamino)maleonitriles and macrocyclic bis(dialkylamino)maleonitriles as fluorescent probes for cations and a new colorimetric copper(II) chemodosimeter JF - Helvetica chimica acta N2 - In this article, we report on the synthesis of acyclic bis(monoalkylamino)maleonitriles and on the intended synthesis of macrocyclic bis(dialkylamino)maleonitriles to get fluorescent probes for cations. During our efforts to synthesize macrocyclic bis(dialkylamino)maleonitriles, we were only able to isolate macrocyclic bis(dialkylamino)-fumaronitriles. The synthesis of macrocyclic bis(dialkylamino)maleonitriles is challenging, due to the fact that bis-(dialkylamino)fumaronitriles are thermodynamically more stable than the corresponding bis(dialkylamino)-maleonitriles. Further, it turned out that the acyclic bis(monoalkylamino)maleonitriles and macrocyclic bis-(dialkylamino)fumaronitriles are no suitable tools to detect cations by a strong fluorescence enhancement. Further, only the bis(monoalkylamino)maleonitriles, which are bearing a 2-pyridyl unit as an additional complexing unit, are able to selectively recognize copper(II) by a color change from yellow to red. KW - copper KW - fumaronitrile KW - ligands KW - macrocycles KW - maleonitrile Y1 - 2021 U6 - https://doi.org/10.1002/hlca.202100028 SN - 1522-2675 VL - 104 IS - 6 SP - e2100028 PB - Wiley-VCH CY - Weinheim ER -