TY - JOUR A1 - Wartenburger, Isabell A1 - Heekeren, Hauke R. A1 - Abutalebi, Jubin A1 - Cappa, Stefano F. A1 - Villringer, Arno A1 - Perani, Daniela T1 - Early setting of grammatical processing in the bilingual brain Y1 - 2003 UR - http://www.cell.com/neuron/home SN - 0896-6273 ER - TY - JOUR A1 - Vitali, P. A1 - Abutalebi, Jubin A1 - Tettamanti, M. A1 - Rowe, J. A1 - Scifo, P. A1 - Fazio, F. A1 - Cappa, Stefano F. A1 - Perani, Daniela T1 - Generating animal and tool names : an fMRI study of effective connectivity N2 - The present fMRI study of semantic fluency for animal and tool names provides further evidence for category- specific brain activations, and reports task-related changes in effective connectivity among defined cerebral regions. Two partially segregated systems of functional integration were highlighted: the tool condition was associated with an enhancement of connectivity within left hemispheric regions, including the inferior prefrontal and premotor cortex, the inferior parietal lobule and the temporo-occipital junction; the animal condition was associated with greater coupling among left visual associative regions. These category-specific functional differences extend the evidence for anatomical specialization to lexical search tasks, and provide for the first time evidence of category-specific patterns of functional integration in word-retrieval. (c) 2004 Elsevier Inc. All rights reserved Y1 - 2005 SN - 0093-934X ER - TY - JOUR A1 - Mariƫn, Peter A1 - Abutalebi, Jubin A1 - Engelborghs, Sebastian A1 - De Deyn, Peter Paul T1 - Pathophysiology of language switching and mixing in an early bilingual child with subcortical aphasia N2 - Acquired aphasia after circumscribed vascular subcortical lesions has not been reported in bilingual children. We report clinical and neuroimaging findings in an early bilingual boy who incurred equally severe transcortical sensory aphasia in his first language (L1) and second language (L2) after a posterior left thalamic hemorrhage. Following recurrent bleeding of the lesion the aphasic symptoms substantially aggravated. Spontaneous pathological language switching and mixing were found in both languages. Remission of these phenomena was reflected on brain perfusion SPECT revealing improved perfusion in the left frontal lobe and left caudate nucleus. The parallelism between the evolution of language symptoms and the SPECT findings may demonstrate that a subcortical left frontal lobe circuity is crucially involved in language switching and mixing Y1 - 2005 ER - TY - JOUR A1 - Perani, Daniela A1 - Abutalebi, Jubin T1 - The neural basis of first and second language processing N2 - Fundamental breakthroughs in the neurosciences, combined with technical innovations for measuring brain activity, are shedding new light on the neural basis of second language (L2) processing, and on its relationship to native language processing (L1). The long-held assumption that L1 and L2 are necessarily represented in different brain regions in bilinguals has not been confirmed. On the contrary, the available evidence indicates that L1 and L2 are processed by the same neural devices. The neural differences in L1 and L2 representations are only related to the specific computational demands, which vary according to the age of acquisition, the degree of mastery and the level of exposure to each language. Finally, the acquisition of L2 could be considered as a dynamic process, requiring additional neural resources in specific circumstances Y1 - 2005 SN - 0959-4388 ER -