TY  - JOUR
A1  - Koelman, Liselot A.
A1  - Pivovarova-Ramich, Olga
A1  - Pfeiffer, Andreas F. H.
A1  - Grune, Tilman
A1  - Aleksandrova, Krasimira
T1  - Cytokines for evaluation of chronic inflammatory status in ageing research
BT  - reliability and phenotypic characterisation
JF  - Immunity & Ageing
N2  - Background: There is a growing interest in the role of inflammageing for chronic disease development. Cytokines are potent soluble immune mediators that can be used as target biomarkers of inflammageing; however, their measurement in human samples has been challenging. This study aimed to assess the reliability of a pro- and anti-inflammatory cytokine panel in a sample of healthy people measured with a novel electrochemiluminescent multiplex immunoassay platform (Meso Scale Discovery, MSD), and to characterize their associations with metabolic and inflammatory phenotypes.
KW  - Reliability
KW  - Cytokines
KW  - Multiplex platforms
KW  - Inflammaging
KW  - Biomarkers
KW  - Ageing
KW  - BMI
Y1  - 2019
U6  - https://doi.org/10.1186/s12979-019-0151-1
SN  - 1742-4933
VL  - 16
PB  - BMC
CY  - London
ER  -