TY  - JOUR
A1  - Brosnan, Sarah M.
A1  - Schlaad, Helmut
T1  - Modification of polypeptide materials by Thiol-X chemistry
JF  - Polymer : the international journal for the science and technology of polymers
N2  - Thiol-X chemistry has proven to be a valuable toolbox for modification of peptides, proteins, monomers, and polymers. Recently, this has become especially true for the modification of polypeptides (monomers or polymers), which has resulted in a plethora of novel polymers and materials. With this in mind, this highlight focuses on the recent literature concerning the modification of polypeptides by the use of thiol-X chemistry, in particular to synthetic polypeptides either at the monomer or polymer stage modified by thiol-ene, -Michael addition, and -yne chemistries. (C) 2014 Published by Elsevier Ltd.
KW  - Polypeptide
KW  - Thiol-X
KW  - Click chemistry
Y1  - 2014
U6  - https://doi.org/10.1016/j.polymer.2014.08.067
SN  - 0032-3861
SN  - 1873-2291
VL  - 55
IS  - 22
SP  - 5511
EP  - 5516
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Goebel, Ronald
A1  - Hesemann, Peter
A1  - Friedrich, Alwin
A1  - Rothe, Regina
A1  - Schlaad, Helmut
A1  - Taubert, Andreas
T1  - Modular thiol-ene chemistry approach towards mesoporous silica monoliths with organically modified pore walls
JF  - Chemistry - a European journal
N2  - The surface modification of mesoporous silica monoliths through thiol-ene chemistry is reported. First, mesoporous silica monoliths with vinyl, allyl, and thiol groups were synthesized through a sol-gel hydrolysis-poly-condensation reaction from tetramethyl orthosilicate (TMOS) and vinyltriethoxysilane, allyltriethoxysilane, and (3-mercaptopropyl) trimethoxysilane, respectively. By variation of the molar ratio of the comonomers TMOS and functional silane, mesoporous silica objects containing different amounts of vinyl, allyl, and thiol groups were obtained. These intermediates can subsequently be derivatized through radical photoaddition reactions either with a thiol or an olefin, depending on the initial pore wall functionality, to yield silica monoliths with different pore-wall chemistries. Nitrogen sorption, small-angle X-ray scattering, solid-state NMR spectroscopy, elemental analysis, thermogravimetric analysis, and redox titration demonstrate that the synthetic pathway influences the morphology and pore characteristics of the resulting monoliths and also plays a significant role in the efficiency of functionalization. Moreover, the different reactivity of the vinyl and allyl groups on the pore wall affects the addition reaction, and hence, the degree of the pore-wall functionalization. This report demonstrates that thiol-ene photoaddition reactions are a versatile platform for the generation of a large variety of organically modified silica monoliths with different pore surfaces.
KW  - mesoporous materials
KW  - photochemistry
KW  - sol-gel processes
KW  - surface chemistry
Y1  - 2014
U6  - https://doi.org/10.1002/chem.201403982
SN  - 0947-6539
SN  - 1521-3765
VL  - 20
IS  - 52
SP  - 17579
EP  - 17589
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - INPR
A1  - Schlaad, Helmut
T1  - Thiol-X chemistry in polymer science
T2  - Polymer : the international journal for the science and technology of polymers
Y1  - 2014
U6  - https://doi.org/10.1016/j.polymer.2014.09.020
SN  - 0032-3861
SN  - 1873-2291
VL  - 55
IS  - 22
SP  - 5509
EP  - 5510
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Tritschler, Ulrich
A1  - Zlotnikov, Igor
A1  - Keckeis, Philipp
A1  - Schlaad, Helmut
A1  - Cölfen, Helmut
T1  - Optical properties of self-organized gold nanorod-polymer hybrid films
JF  - Langmuir
N2  - High fractions of gold nanorods were locally aligned by means of a polymeric liquid crystalline phase. The gold nanorods constituting >80 wt % of the thin organic-inorganic composite films form a network with side-by-side and end-to-end combinations. Organization into these network structures was induced by shearing gold nanorod-LC polymer dispersions via spin-coating. The LC polymer is a polyoxazoline functionalized with pendent cholesteryl and carboxyl side groups enabling the polymer to bind to the CTAB stabilizer layer of the gold nanorods via electrostatic interactions, thus forming the glue between organic and inorganic components, and to form a chiral nematic lyotropic phase. The self-assembled locally oriented gold nanorod structuring enables control over collective optical properties due to plasmon resonance coupling, reminiscent of enhanced optical properties of natural biomaterials.
Y1  - 2014
U6  - https://doi.org/10.1021/la503507u
SN  - 0743-7463
VL  - 30
IS  - 46
SP  - 13781
EP  - 13790
PB  - American Chemical Society
CY  - Washington
ER  -