TY - JOUR A1 - Baake, Ellen A1 - Baake, Michael A1 - Bovier, Anton A1 - Klein, Markus T1 - An asymptotic maximum principle for essentially linear evolution models N2 - Recent work on mutation-selection models has revealed that, under specific assumptions on the fitness function and the mutation rates, asymptotic estimates for the leading eigenvalue of the mutation-reproduction matrix may be obtained through a low-dimensional maximum principle in the limit N --> infinity (where N, or N-d with d greater than or equal to 1, is proportional to the number of types). In order to extend this variational principle to a larger class of models, we consider here a family of reversible matrices of asymptotic dimension N-d and identify conditions under which the high-dimensional Rayleigh-Ritz variational problem may be reduced to a low-dimensional one that yields the leading eigenvalue up to an error term of order 1/N. For a large class of mutation-selection models, this implies estimates for the mean fitness, as well as a concentration result for the ancestral distribution of types Y1 - 2005 SN - 0303-6812 ER - TY - JOUR A1 - Bovier, Anton A1 - Gayrard, Veronique A1 - Klein, Markus T1 - Metastability in reversible diffusion processes : II. Precise asymptotics for small eigenvalues N2 - We continue the analysis of the problem of metastability for reversible diffusion processes, initiated in [BEGK3], with a precise analysis of the low-lying spectrum of the generator. Recall that we are considering processes with generators of the form -epsilonDelta + delF(.) del on R-d or subsets of Rd, where F is a smooth function with finitely many local minima. Here we consider only the generic situation where the depths of all local minima are different. We show that in general the exponentially small part of the spectrum is given, up to multiplicative errors tending to one, by the eigenvalues of the classical capacity matrix of the array of capacitors made of balls of radius epsilon centered at the positions of the local minima of F. We also get very precise uniform control on the corresponding eigenfunctions. Moreover, these eigenvalues can be identified with the same precision with the inverse mean metastable exit times from each minimum. In [BEGK3] it was proven that these mean times are given, again up to multiplicative errors that tend to one, by the classical Eyring- Kramers formula Y1 - 2005 SN - 1435-9855 ER - TY - JOUR A1 - Klein, Markus A1 - Korotyaev, Evgeni A1 - Pokrovski, A. T1 - Spectral asymptotics of the harmonic oscillator perturbed by bounded potentials N2 - Consider the operator T = -d(2)/dx(2) + x(2) + q(x) in L-2 (R), where q is a real function with q' and integral(0)(x) q(s) ds bounded. The spectrum of T is purely discrete and consists of simple eigenvalues. We determine their asymptotics mu(n) = (2n + 1) + (2 pi)(-1) integral(-pi)(pi) q(root 2n+1 sin theta)d theta + O(n(-1/3)) and we extend these results for complex q. Y1 - 2005 SN - 1424-0637 ER -