TY  - JOUR
A1  - Booker, Anke
A1  - Jacob, Louis E. C.
A1  - Rapp, Michael Armin
A1  - Bohlken, Jens
A1  - Kostev, Karel
T1  - Risk factors for dementia diagnosis in German primary care practices
JF  - International psychogeriatrics
N2  - Background: Dementia is a psychiatric condition the development of which is associated with numerous aspects of life. Our aim was to estimate dementia risk factors in German primary care patients.
 Methods: The case-control study included primary care patients (70-90 years) with first diagnosis of dementia (all-cause) during the index period (01/2010-12/2014) (Disease Analyzer, Germany), and controls without dementia matched (1:1) to cases on the basis of age, sex, type of health insurance, and physician. Practice visit records were used to verify that there had been 10 years of continuous follow-up prior to the index date. Multivariate logistic regression models were fitted with dementia as a dependent variable and the potential predictors.
 Conclusions: Risk factors for dementia found in this study are consistent with the literature. Nevertheless, the associations between statin, PPI and antihypertensive drug use, and decreased risk of dementia need further investigations.
KW  - dementia
KW  - Alzheimer
KW  - risk factors
KW  - statins
Y1  - 2016
U6  - https://doi.org/10.1017/S1041610215002082
SN  - 1041-6102
SN  - 1741-203X
VL  - 28
SP  - 1059
EP  - 1065
PB  - Cambridge Univ. Press
CY  - New York
ER  - 
TY  - JOUR
A1  - Konrad, Marcel
A1  - Bohlken, Jens
A1  - Rapp, Michael Armin
A1  - Kostev, Karel
T1  - Depression risk in patients with heart failure in primary care practices in Germany
JF  - International psychogeriatrics
N2  - Background: The goal of this study was to estimate the prevalence of and risk factors for diagnosed depression in heart failure (HF) patients in German primary care practices. Methods: This study was a retrospective database analysis in Germany utilizing the Disease Analyzer (R) Database (IMS Health, Germany). The study population included 132,994 patients between 40 and 90 years of age from 1,072 primary care practices. The observation period was between 2004 and 2013. Follow-up lasted up to five years and ended in April 2015. A total of 66,497 HF patients were selected after applying exclusion criteria. The same number of 66,497 controls were chosen and were matched (1:1) to HF patients on the basis of age, sex, health insurance, depression diagnosis in the past, and follow-up duration after index date. Results: HF was a strong risk factor for diagnosed depression (p < 0.0001). A total of 10.5% of HF patients and 6.3% of matched controls developed depression after one year of follow-up (p < 0.001). Depression was documented in 28.9% of the HF group and 18.2% of the control group after the five-year follow-up (p < 0.001). Cancer, dementia, osteoporosis, stroke, and osteoarthritis were associated with a higher risk of developing depression. Male gender and private health insurance were associated with lower risk of depression. Conclusions: The risk of diagnosed depression is significantly increased in patients with HF compared to patients without HF in primary care practices in Germany.
KW  - depression
KW  - primary care
KW  - risk factors
KW  - antidepressants
Y1  - 2016
U6  - https://doi.org/10.1017/S1041610216000867
SN  - 1041-6102
SN  - 1741-203X
VL  - 28
SP  - 1889
EP  - 1894
PB  - Cambridge Univ. Press
CY  - New York
ER  - 
TY  - JOUR
A1  - Krahé, Barbara
A1  - Vanwesenbeeck, Ine
T1  - Mapping an agenda for the study of youth sexual aggression in Europe: assessment, principles of good practice, and the multilevel analysis of risk factors
JF  - Journal of sexual aggression
N2  - Sexual aggression is a serious threat to young people's sexual health in Europe, but establishing the exact scale of the problem has been hampered by a variety of conceptual and methodological problems. This article presents a framework for studying youth sexual aggression that addresses both prevalence and risk factors of victimisation and perpetration. It proposes a research tool to comprehensively assess the perpetration of, and victimisation by, sexual aggression that captures different coercive strategies, sexual acts, victim–perpetrator relations, and gender constellations. The instrument is rooted in a clear conceptual definition of sexual aggression and was pilot-tested in 10 countries of the European Union (EU). Furthermore, a list of good practice criteria is proposed to promote the quality and comparability of research on youth sexual aggression in Europe. A multilevel approach combining individual-level and country-level predictors of sexual aggression is outlined and illustrated with data from the pilot study in 10 countries.
KW  - Sexual aggression
KW  - sexual victimisation
KW  - youth
KW  - measurement
KW  - risk factors
KW  - Europe
Y1  - 2016
U6  - https://doi.org/10.1080/13552600.2015.1066885
SN  - 1355-2600
SN  - 1742-6545
VL  - 22
SP  - 161
EP  - 174
PB  - Karger
CY  - Abingdon
ER  -