TY - JOUR A1 - Kietzke, Thomas A1 - Neher, Dieter A1 - Kumke, Michael Uwe A1 - Montenegro, Rivelino V. D. A1 - Landfester, Katharina A1 - Scherf, Ullrich T1 - A nanoparticle approach to control the phase separation in polyfluorene photovoltaic devices N2 - Polymer solar cell devices with nanostructured blend layers have been fabricated using single- and dual- component polymer nanospheres. Starting from an electron-donating and an electron-accepting polyfluorene derivative, PFB and F8BT, dissolved in suitable organic solvents, dispersions of solid particles with mean diameters of ca. 50 nm, containing either the pure polymer components or a mixture of PFB and F8BT in each particle, were prepared with the miniemulsion process. Photovoltaic devices based on these particles have been studied with respect to the correlation between external quantum efficiency and layer composition. It is shown that the properties of devices containing a blend of single-component PFB and F8BT particles differ significantly from those of solar cells based on blend particles, even for the same layer composition. Various factors determining the quantum efficiency in both kinds of devices are identified and discussed, taking into account the spectroscopic properties of the particles. An external quantum efficiency of ca. 4% is measured for a device made from polymer blend nanoparticles containing PFB:F8BT at a weight ratio of 1:2 in each individual nanosphere. This is among the highest values reported so far for photovoltaic cells using this material combination Y1 - 2004 ER - TY - JOUR A1 - Vorgerd, M. A1 - vanderVen, Peter F. M. A1 - Bruchertseifer, V. A1 - Lowe, T. A1 - Kley, R. A. A1 - Schröder, Rolf A1 - Lochmuller, H. A1 - Himmel, Mirko A1 - Koehler, K. A1 - Fürst, Dieter Oswald A1 - Huebner, A. T1 - A mutation in the dimerization domain of filamin C causes a novel type of autosomal dominant myofibrillar myopathy N2 - Myofibrillar myopathy (MFM) is a human disease that is characterized by focal myofibrillar destruction and pathological cytoplasmic protein aggregations. In an extended German pedigree with a novel form of MFM characterized by clinical features of a limb-girdle myopathy and morphological features of MFM, we identified a cosegregating, heterozygous nonsense mutation (8130G -> A; W2710X) in the filamin c gene ( FLNC) on chromosome 7q32.1. The mutation is the first found in FLNC and is localized in the dimerization domain of filamin c. Functional studies showed that, in the truncated mutant protein, this domain has a disturbed secondary structure that leads to the inability to dimerize properly. As a consequence of this malfunction, the muscle fibers of our patients display massive cytoplasmic aggregates containing filamin c and several Z-disk-associated and sarcolemmal proteins Y1 - 2005 SN - 0002-9297 ER - TY - JOUR A1 - Shirzadian-Khorramabad, Reza A1 - Jing, Hai-Chun A1 - Everts, Gerja E. A1 - Schippers, Jos H. M. A1 - Hille, Jacques A1 - Dijkwel, Paul P. T1 - A mutation in the cytosolic O-acetylserine (thiol) lyase induces a genome-dependent early leaf death phenotype in Arabidopsis N2 - Background: Cysteine is a component in organic compounds including glutathione that have been implicated in the adaptation of plants to stresses. O-acetylserine (thiol) lyase (OAS-TL) catalyses the final step of cysteine biosynthesis. OAS-TL enzyme isoforms are localised in the cytoplasm, the plastids and mitochondria but the contribution of individual OAS-TL isoforms to plant sulphur metabolism has not yet been fully clarified. Results: The seedling lethal phenotype of the Arabidopsis onset of leaf death3-1 (old3-1) mutant is due to a point mutation in the OAS-A1 gene, encoding the cytosolic OAS-TL. The mutation causes a single amino acid substitution from Gly(162) to Glu(162), abolishing old3-1 OAS-TL activity in vitro. The old3-1 mutation segregates as a monogenic semidominant trait when backcrossed to its wild type accession Landsberg erecta (Ler-0) and the Di-2 accession. Consistent with its semi- dominant behaviour, wild type Ler-0 plants transformed with the mutated old3-1 gene, displayed the early leaf death phenotype. However, the old3-1 mutation segregates in an 11: 4: 1 (wild type: semi-dominant: mutant) ratio when backcrossed to the Colombia-0 and Wassilewskija accessions. Thus, the early leaf death phenotype depends on two semi- dominant loci. The second locus that determines the old3-1 early leaf death phenotype is referred to as odd-ler (for old3 determinant in the Ler accession) and is located on chromosome 3. The early leaf death phenotype is temperature dependent and is associated with increased expression of defence-response and oxidative-stress marker genes. Independent of the presence of the odd-ler gene, OAS-A1 is involved in maintaining sulphur and thiol levels and is required for resistance against cadmium stress. Conclusions: The cytosolic OAS-TL is involved in maintaining organic sulphur levels. The old3-1 mutation causes genome-dependent and independent phenotypes and uncovers a novel function for the mutated OAS- TL in cell death regulation. Y1 - 2010 UR - http://www.biomedcentral.com/1471-2229/ U6 - https://doi.org/10.1186/1471-2229-10-80 SN - 1471-2229 ER - TY - JOUR A1 - Weilbacher, Peter Michael A1 - Monreal-Ibero, Ana A1 - Kollatschny, Wolfram A1 - Ginsburg, Adam A1 - McLeod, Anna F. A1 - Kamann, Sebastian A1 - Sandin, Christer A1 - Palsa, Ralf A1 - Wisotzki, Lutz A1 - Bacon, Roland A1 - Selman, Fernando A1 - Brinchmann, Jarle A1 - Caruana, Joseph A1 - Kelz, Andreas A1 - Martinsson, Thomas A1 - Pecontal-Rousset, Arlette A1 - Richard, Johan A1 - Wendt, Martin T1 - A MUSE map of the central Orion Nebula (M 42) JF - Astronomy and astrophysics : an international weekly journal N2 - We present a new integral field spectroscopic dataset of the central part of the Orion Nebula (M 42), observed with the MUSE instrument at the ESO VLT. We reduced the data with the public MUSE pipeline. The output products are two FITS cubes with a spatial size of similar to 5'9 x 4'9 (corresponding to similar to 0.76 x 0.63 pc(2)) and a contiguous wavelength coverage of 4595 ... 9366 angstrom, spatially sampled at 0 ''.2. We provide two versions with a sampling of 1.25 angstrom and 0.85 angstrom in dispersion direction. Together with variance cubes these files have a size of 75 and 110 GiB on disk. They are the largest integral field mosaics to date in terms of information content. We make them available for use in the community. To validate this dataset, we compare world coordinates, reconstructed magnitudes, velocities, and absolute and relative emission line fluxes to the literature values and find excellent agreement. We derive a 2D map of extinction and present de-reddened flux maps of several individual emission lines and of diagnostic line ratios. We estimate physical properties of the Orion Nebula, using the emission line ratios [N II] and [S III] (for the electron temperature T-e) and [S II] and [Cl III] (for the electron density N-e), and show 2D images of the velocity measured from several bright emission lines. KW - H II regions KW - ISM: individual objects: M 42 KW - open clusters and associations: individual: Trapezium cluster Y1 - 2015 U6 - https://doi.org/10.1051/0004-6361/201526529 SN - 1432-0746 VL - 582 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - González-Galán, Ana A1 - Oskinova, Lida A1 - Popov, Sergei B. A1 - Haberl, F. A1 - Kühnel, M. A1 - Gallagher, John S. A1 - Schurch, Matthew A1 - Guerrero, Martín A. T1 - A multiwavelength study of SXP 1062, the long-period X-ray pulsar associated with a supernova remnant JF - Monthly notices of the Royal Astronomical Society N2 - SXP 1062 is a Be X-ray binary (BeXB) located in the Small Magellanic Cloud. It hosts a long-period X-ray pulsar and is likely associated with the supernova remnant MCSNR J0127−7332. In this work we present a multiwavelength view on SXP 1062 in different luminosity regimes. We consider monitoring campaigns in optical (OGLE survey) and X-ray (Swift telescope). During these campaigns a tight coincidence of X-ray and optical outbursts is observed. We interpret this as typical Type I outbursts as often detected in BeXBs at periastron passage of the neutron star (NS). To study different X-ray luminosity regimes in depth, during the source quiescence we observed it with XMM–Newton while Chandra observations followed an X-ray outburst. Nearly simultaneously with Chandra observations in X-rays, in optical the RSS/SALT telescope obtained spectra of SXP 1062. On the basis of our multiwavelength campaign we propose a simple scenario where the disc of the Be star is observed face-on, while the orbit of the NS is inclined with respect to the disc. According to the model of quasi-spherical settling accretion our estimation of the magnetic field of the pulsar in SXP 1062 does not require an extremely strong magnetic field at the present time. KW - stars: neutron KW - pulsars: individual: SXP 1062 KW - galaxies: individual: Small Magellanic Cloud KW - X-rays: binaries Y1 - 2017 U6 - https://doi.org/10.1093/mnras/stx3127 SN - 0035-8711 SN - 1365-2966 VL - 475 IS - 2 SP - 2809 EP - 2821 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Plessner, Henning A1 - Schweizer, Geoffrey A1 - Brand, Ralf A1 - O'Hare, David T1 - A multiple-cue learning approach as the basis for understanding and improving soccer referees' decision making Y1 - 2009 SN - 978-0-444-53356-2 ER - TY - JOUR A1 - Logacev, Pavel A1 - Vasishth, Shravan T1 - A Multiple-Channel Model of Task-Dependent Ambiguity Resolution in Sentence Comprehension JF - Cognitive science : a multidisciplinary journal of anthropology, artificial intelligence, education, linguistics, neuroscience, philosophy, psychology ; journal of the Cognitive Science Society N2 - Traxler, Pickering, and Clifton (1998) found that ambiguous sentences are read faster than their unambiguous counterparts. This so-called ambiguity advantage has presented a major challenge to classical theories of human sentence comprehension (parsing) because its most prominent explanation, in the form of the unrestricted race model (URM), assumes that parsing is non-deterministic. Recently, Swets, Desmet, Clifton, and Ferreira (2008) have challenged the URM. They argue that readers strategically underspecify the representation of ambiguous sentences to save time, unless disambiguation is required by task demands. When disambiguation is required, however, readers assign sentences full structure—and Swets et al. provide experimental evidence to this end. On the basis of their findings, they argue against the URM and in favor of a model of task-dependent sentence comprehension. We show through simulations that the Swets et al. data do not constitute evidence for task-dependent parsing because they can be explained by the URM. However, we provide decisive evidence from a German self-paced reading study consistent with Swets et al.'s general claim about task-dependent parsing. Specifically, we show that under certain conditions, ambiguous sentences can be read more slowly than their unambiguous counterparts, suggesting that the parser may create several parses, when required. Finally, we present the first quantitative model of task-driven disambiguation that subsumes the URM, and we show that it can explain both Swets et al.'s results and our findings. KW - Sentence processing KW - Ambiguity KW - Parallel processing KW - Cognitive modeling KW - Unrestricted race model KW - URM KW - Underspecification KW - Good-enough processing Y1 - 2016 U6 - https://doi.org/10.1111/cogs.12228 SN - 0364-0213 SN - 1551-6709 VL - 40 SP - 266 EP - 298 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Hatzichristou, C. A1 - Hopf, Diether T1 - A multiperspective comparison of peer sociometric status groups in childhood and adolescence Y1 - 1996 ER - TY - JOUR A1 - Schwarzenthal, Miriam A1 - Juang, Linda P. A1 - Schachner, Maja Katharina A1 - van de Vijver, Fons J. R. T1 - A multimodal measure of cultural intelligence for adolescents growing up in culturally diverse societies JF - International Journal of Intercultural Relations N2 - Adolescents growing up in culturally diverse societies need to develop intercultural competence. To better understand how to develop intercultural competence we need measures specifically relating to the everyday intercultural experiences of adolescents. However, few measures of intercultural competence are available for this target group. Based on the cultural intelligence (CQ) model (Earley & Ang, 2003), we developed a measure that combines a self-report questionnaire and situational judgment tests (SJTs). The latter comprise a brief description of intercultural situations, followed by questions asking the adolescents to interpret and provide a reaction to the situations. The reliability, factor structure, measurement equivalence, and validity of the new measure was tested in two samples of adolescents in culturally diverse regions in North Rhine-Westphalia (N = 631, 48% female, M-a(ge) = 13.69 years, SDage = 1.83) and Berlin (N = 1,335, 48% female, M-age = 14.69 years, SDage, = 0.74) in Germany. The self-report CQ scale showed good reliability and a four-dimensional factor structure with a higher-order CQ factor. The responses to the SJTs were coded based on a coding manual and the ratings loaded onto one factor. The measurement models showed metric to scalar measurement equivalence across immigrant background, gender, and grade. The CQ factor and the SJT factor were positively correlated with each other, as well as with related constructs such as openness, perspective-taking, and diversity beliefs. We conclude that the new measure offers a reliable and valid method to assess the intercultural competence of adolescents growing up in culturally diverse societies. KW - Cultural intelligence KW - Intercultural competence KW - Adolescents Y1 - 2019 U6 - https://doi.org/10.1016/j.ijintrel.2019.07.007 SN - 0147-1767 SN - 1873-7552 VL - 72 SP - 109 EP - 121 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Sarauli, David A1 - Xu, Chenggang A1 - Dietzel, Birgit A1 - Schulz, Burkhard A1 - Lisdat, Fred T1 - A multilayered sulfonated polyaniline network with entrapped pyrroloquinoline quinone-dependent glucose dehydrogenase: tunable direct bioelectrocatalysis JF - Journal of materials chemistry : B, Materials for biology and medicine N2 - A feasible approach to construct multilayer films of sulfonated polyanilines - PMSA1 and PABMSA1 containing different ratios of aniline, 2-methoxyaniline-5-sulfonic acid (MAS) and 3-aminobenzoic acid (AB), with the entrapped redox enzyme pyrroloquinoline quinone-dependent glucose dehydrogenase (PQQ-GDH) on Au and ITO electrode surfaces, is described. The formation of layers has been followed and confirmed by electrochemical impedance spectroscopy (EIS), which demonstrates that the multilayer assembly can be achieved in a progressive and uniform manner. The gold and ITO electrodes subsequently modified with PMSA1:PQQ-GDH and PABMSA1 films are studied by cyclic voltammetry (CV) and UV-Vis spectroscopy which show a significant direct bioelectrocatalytical response to the oxidation of the substrate glucose without any additional mediator. This response correlates linearly with the number of deposited layers. Furthermore, the constructed polymer/enzyme multilayer system exhibits a rather good long-term stability, since the catalytic current response is maintained for more than 60% of the initial value even after two weeks of storage. This verifies that a productive interaction of the enzyme embedded in the film of substituted polyaniline can be used as a basis for the construction of bioelectronic units, which are useful as indicators for processes liberating glucose and allowing optical and electrochemical transduction. Y1 - 2014 U6 - https://doi.org/10.1039/c4tb00336e SN - 2050-750X SN - 2050-7518 VL - 2 IS - 21 SP - 3196 EP - 3203 PB - Royal Society of Chemistry CY - Cambridge ER -